Clifford S. Patlak

Clifford S. Patlak's AcademicInfluence.com Rankings

Clifford S. Patlak

Physics

#3959

World Rank

#5520

Historical Rank

Biophysics

#110

World Rank

#118

Historical Rank

physics Degrees

Clifford S. Patlak

Biology

#5978

World Rank

#8590

Historical Rank

Neuroscience

#701

World Rank

#733

Historical Rank

biology Degrees

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Physics
Biology

Clifford S. Patlak's Degrees

PhD Biophysics University of California, Berkeley
Bachelors Physics University of California, Berkeley

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Clifford S. Patlak's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

THE [14C]DEOXYGLUCOSE METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE UTILIZATION: THEORY, PROCEDURE, AND NORMAL VALUES IN THE CONSCIOUS AND ANESTHETIZED ALBINO RAT 1 (1977) (5944)
Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data (1983) (3622)
Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data. Generalizations (1985) (1657)
Random walk with persistence and external bias (1953) (908)
Transport of α-Aminoisobutyric Acid across Brain Capillary and Cellular Membranes (1983) (506)
The flow of solute and solvent across a two-membrane system. (1963) (390)
Drainage of interstitial fluid from different regions of rat brain. (1984) (334)
Intrathecal chemotherapy: brain tissue profiles after ventriculocisternal perfusion. (1975) (327)
Efflux of radiolabeled polyethylene glycols and albumin from rat brain. (1981) (293)
Fate of Cerebrospinal Fluid‐Borne Amyloid β‐Peptide: Rapid Clearance into Blood and Appreciable Accumulation by Cerebral Arteries (1996) (239)
Methods for Quantifying the transport of drugs across brain barrier systems. (1981) (239)
Extracellular space of brain as determined by diffusion of inulin from the ventricular system (1962) (234)
Measurements of dog blood-brain transfer constants by ventriculocisternal perfusion. (1975) (207)
Sucrose and inulin space measurements of cerebral cortex in four mammalian species. (1970) (199)
Characteristics of p-aminohippurate transport in proximal renal tubules. (1969) (193)
Albumin outflow into deep cervical lymph from different regions of rabbit brain. (1991) (170)
Selective reduction of radiotracer trapping by deuterium substitution: comparison of carbon-11-L-deprenyl and carbon-11-deprenyl-D2 for MAO B mapping. (1995) (155)
Contributions to the theory of active transport: II. The gate type non-carrier mechanism and generalizations concerning tracer flow, efficiency, and measurement of energy expenditure (1957) (151)
Slow recovery of human brain MAO B after L‐Deprenyl (Selegeline) withdrawal (1994) (150)
Extracellular volume decreases while cell volume is maintained by ion uptake in rat brain during acute hypernatremia. (1991) (148)
Volume regulatory loss of Na, Cl, and K from rat brain during acute hyponatremia. (1987) (118)
Distribution of methotrexate in the cerebrospinal fluid and brain after intraventricular administration. (1977) (114)
Hypoxia Increases Velocity of Blood Flow through Parenchymal Microvascular Systems in Rat Brain (1993) (105)
Transport of alpha-aminoisobutyric acid across brain capillary and cellular membranes. (1983) (102)
A method to obtain infusion schedules for prescribed blood concentration time courses. (1976) (102)
Striatal 18F-DOPA Uptake: Absence of an Aging Effect (1993) (101)
The microcirculation of rat circumventricular organs and pituitary gland (1987) (100)
Ontogeny of blood-brain barrier function in ovine fetuses, lambs, and adults. (1996) (95)
Regulation of brain water and electrolytes during acute hyperosmolality in rats. (1987) (94)
Permeability limitation in estimation of local brain blood flow with [14C]antipyrine. (1975) (92)
Selection of Experimental Conditions for the Accurate Determination of Blood — Brain Transfer Constants from Single-Time Experiments: A Theoretical Analysis (1983) (92)
Dexamethasone Effects on [125I]Albumin Distribution in Experimental RG-2 Gliomas and Adjacent Brain (1987) (91)
A component of fluid absorption linked to passive ion flows in the superficial pars recta (1975) (90)
Increased blood-brain transfer in a rabbit model of acute liver failure (1983) (86)
Organic solutes in fluid absorption by renal proximal convoluted tubules. (1981) (84)
Analysis of brain uptake and loss or radiotracers after intracarotid injection. (1975) (84)
An Evaluation of Errors in the Determination of Blood Flow by the Indicator Fractionation and Tissue Equilibration (Kety) Methods (1984) (82)
Hypercapnia slightly raises blood volume and sizably elevates flow velocity in brain microvessels. (1993) (82)
Quantitative measurements of capillary transport in human brain tumors by computed tomography (1991) (78)
Volume regulatory influx of electrolytes from plasma to brain during acute hyperosmolality. (1987) (76)
Regional localization of a glioma-associated antigen defined by monoclonal antibody 81C6 in vivo: kinetics and implications for diagnosis and therapy. (1987) (75)
Effect of certain drugs on cerebrospinal fluid production in the dog (1964) (73)
The Movements of Water and Solutes in the Brains of Mammals (1976) (72)
In normal rat, intraventricularly administered insulin-like growth factor-1 is rapidly cleared from CSF with limited distribution into brain (2005) (72)
A critical evaluation of the principles governing the advantages of intra-arterial infusions (1974) (69)
Local Cerebral Glucose Utilization in Controlled Graded Levels of Hyperglycemia in the Conscious Rat (1988) (66)
Susceptibility changes following bolus injections (1993) (64)
Local cerebral glucose utilization in fetal and neonatal sheep. (1981) (64)
Exogenous and endogenous corticosteroids modulate blood-brain barrier development in the ovine fetus. (2000) (63)
Secretion and Bulk Flow of Interstitial Fluid (1992) (62)
Combined FDOPA and 3OMFD PET studies in Parkinson's disease. (1996) (60)
A mathematical contribution to the study of orientation of organisms (1953) (59)
Brain ion and volume regulation during acute hypernatremia in Brattleboro rats. (1989) (59)
THE EXCHANGE OF MATERIAL BETWEEN CEREBROSPINAL FLUID AND BRAIN (1975) (58)
Heuristic modeling of drug delivery to malignant brain tumors (1980) (58)
The Velocities of Red Cell and Plasma Flows through Parenchymal Microvessels of Rat Brain are Decreased by Pentobarbital (1993) (58)
Contributions to the theory of active transport (1956) (57)
Regional blood flow, capillary permeability, and glucose utilization in two brain tumor models: preliminary observations and pharmacokinetic implications. (1981) (56)
Increased blood-brain transfer in a rabbit model of acute liver failure. (1983) (54)
The Influence of Tissue Heterogeneity on Results of Fitting Nonlinear Model Equations to Regional Tracer Uptake Curves: With an Application to Compartmental Models Used in Positron Emission Tomography (1987) (54)
Quantitative autoradiographic studies of brain edema and a comparison of multi-isotope autoradiographic techniques. (1980) (54)
Antenatal steroids decrease blood-brain barrier permeability in the ovine fetus. (1999) (54)
Effects of insulin on hexose transport across blood-brain barrier in normoglycemia. (1987) (51)
Effects of arginine vasopressin and atriopeptin on glial cell volume measured as 3-MG space. (1993) (50)
A Spatial Analysis of the Blood—Brain Barrier Damage in Experimental Allergic Encephalomyelitis (1985) (49)
Nicotine Raises the Influx of Permeable Solutes across the Rat Blood—Brain Barrier with Little or No Capillary Recruitment (1995) (49)
Kinetic Analysis of 3-Quinuclidinyl 4-[125I]Iodobenzilate Transport and Specific Binding to Muscarinic Acetylcholine Receptor in Rat Brain in vivo: Implications for Human Studies (1990) (48)
Volume absorption in the pars recta. II. Hydraulic conductivity coefficient. (1978) (47)
Cerebral glucose utilization and blood flow in adult spontaneously hypertensive rats. (1992) (47)
3-Methoxy-4-hydroxyphenylethyleneglycol (MHPG) transport from the spinal cord during spinal subarachnoid perfusion (1976) (46)
Theoretical Analysis of Net Tracer Flux Due to Volume Circulation in a Membrane with Pores of Different Sizes (1971) (46)
Concurrent measurements of blood flow and transcapillary transport in avian sarcoma virus-induced experimental brain tumors: implications for chemotherapy. (1984) (44)
Regulation of Brain Volume Under Isosmotic and Anisosmotic Conditions (1991) (43)
Kinetic analysis of blood-brain barrier transport of D-glucose in man: quantitative evaluation in the presence of tracer backflux and capillary heterogeneity. (1990) (42)
A compartmental analysis of 24Na kinetics in rat cerebrum, sciatic nerve and cerebrospinal fluid (1972) (41)
Transport of material between brain extracellular fluid, brain cells and blood. (1974) (40)
Asymmetrical Transport of Amino Acids across the Blood—Brain Barrier in Humans (1990) (40)
Changes in blood-brain transfer parameters induced by hyperosmolar intracarotid infusion and by metastatic tumor growth. (1980) (39)
Fluid absorption and active and passive ion flows in the rabbit superficial pars recta. (1977) (39)
Variation in local cerebral blood flow response to high-dose pentobarbital sodium in the rat. (1991) (37)
Slightly altered permeability-surface area products imply some cerebral capillary recruitment during hypercapnia. (1994) (37)
Kinetic analysis of cerebrovascular transport based on indicator diffusion technique. (1989) (37)
Derivation of an Equation for the Diffusion Potential (1960) (36)
Nicotine increases microvascular blood flow and flow velocity in three groups of brain areas. (1993) (34)
Pentobarbital produces dissimilar changes in glucose influx and utilization in brain. (1991) (34)
Estimating Blood and Brain Concentrations and Blood-to-Brain Influx by Magnetic Resonance Imaging with Step-Down Infusion of Gd-DTPA in Focal Transient Cerebral Ischemia and Confirmation by Quantitative Autoradiography with Gd-[14C]DTPA (2009) (34)
Regional measurements of [14C]misonidazole distribution and blood flow in subcutaneous RT-9 experimental tumors. (1985) (33)
Technique-dependent variations in cerebral microvessel blood volumes and hematocrits in the rat. (1992) (33)
Quantitative evaluation of the loss of human platelet dense bodies following stimulation by thrombin or A23187. (1977) (33)
Potential difference of the ventricular fluid in vivo and in vitro in the dogfish (1966) (32)
The MRI‐measured arterial input function resulting from a bolus injection of Gd‐DTPA in a rat model of stroke slightly underestimates that of Gd‐[14C]DTPA and marginally overestimates the blood‐to‐brain influx rate constant determined by Patlak plots (2010) (32)
Derivation of Equations for the Steady-State Reaction Velocity of a Substance Based on the Use of a Second Substance (1981) (30)
Energy expenditure by active transport mechanisms. (1960) (30)
VENTRICULAR FLUID PRODUCTION RATES AND TURNOVER IN ELASMOBRANCHII. (1964) (29)
Exchange of inulin and dextran between blood and cerebrospinal fluid. (1961) (29)
A theoretical treatmnt for the kinetics of monolayer desorption from interfaces. (1967) (27)
Effects of postnatal dexamethasone on blood-brain barrier permeability and brain water content in newborn lambs. (2001) (27)
Effect of Vasopressin on Ependymal and Cerebral Capillary Permeability to Tritiated Water in Cat (1986) (27)
Increased peritoneal solute transport in diabetic peritoneal dialysis patients. (1995) (26)
Compartments of protein metabolism in the developing brain. (1979) (25)
Effect of vasopressin on ependymal and capillary permeability to tritiated water in cat (1986) (24)
Drug delivery to CNS tumors. (1981) (22)
Principles of Susceptibility Contrast-Based Functional MRI: The Sign of the Functional MRI Response (2000) (21)
Effects of acute hyperosmolality on blood-brain barrier function in ovine fetuses and lambs. (2006) (21)
Cerebral blood volume measurements by rapid contrast infusion and T 2* ‐weighted echo planar MRI (2002) (20)
Effects of duration of positive-pressure ventilation on blood-brain barrier function in premature lambs (2000) (20)
In situ drug delivery. (1980) (20)
Regulation of brain water during acute hyperosmolality in ovine fetuses, lambs, and adults. (2003) (17)
CNS, CSF, and extradural fluid uptake of various hydrophilic materials in the dogfish. (1977) (16)
Blood-brain barrier permeability measurements by double-indicator method using intravenous injection. (1994) (15)
Dexamethasone effects on vascular volume and tissue hematocrit in experimental RG-2 gliomas and adjacent brain (1988) (15)
The role of unstirred layers for water exchange across the blood-brain barrier. (1981) (14)
Kinetic Analysis of Transport and Opioid Receptor Binding of [3H](−)-Cyclofoxy in Rat Brain in vivo: Implications for Human Studies (1991) (14)
Transport of 5-hydroxy-3-indoleacetic acid by spinal cord during subarachnoid perfusion (1976) (14)
Effects of Multiple Courses of Antenatal Corticosteroids on Blood-Brain Barrier Permeability in the Ovine Fetus (2006) (14)
Kinetic Analysis of 3-Quinuclidinyl 4-[125] Iodobenzilate Transport and Specific Binding to Muscarinic Acetylcholine Receptor in Rat Brain In Vivo (1989) (13)
Experimental Estimates of the Constants Relating Signal Change to Contrast Concentration for Cerebral Blood Volume by T2* MRI (2006) (13)
On expectations of some functions of Poisson variates. (1968) (13)
Energy expenditure by active transport mechanisms. II. Further generalizations. (1961) (12)
Cerebrovascular transport of [125I]quinuclidinyl benzilate, [3H]cyclofoxy, and [14C]iodoantipyrine. (1990) (12)
Activity Coefficients of Monomolecular Films from Desorption Studies (1966) (12)
A contribution to the study of diffusion of neutral particles through pores (1959) (12)
Virtually Unaltered Permeability‐Surface Area Products Imply Little Capillary Recruitment in Brain with Hypoxia (1994) (11)
CHAPTER 46 – Fluorodopa Positron Emission Tomography with an Inhibitor of Catechol-O-methyltransferase: Effect of the Plasma 3-O-methyldopa Fraction on Data Analysis (1996) (10)
Effects of dexamethasone on blood flow and volume of perfused microvessels in traumatic brain edema. (1990) (10)
Quantitative autoradiographic assessment of 55Fe-RBC distribution in rat brain. (1990) (9)
Calcium Compartments in Brain (2002) (9)
Comparative Effects of Glucose- and Mannitol-Induced Osmolar Stress on Blood—Brain Barrier Function in Ovine Fetuses and Lambs (2012) (9)
Rapid dynamic CT scanning to distinguish schizophrenic from normal subjects (1987) (9)
Correlations between Plasminogen Activator Inhibitor-1 and Peritoneal Transport in Pediatric Ccpd Patients (1995) (8)
The logarithmic convexity of the washout function in tracer kinetics (1969) (8)
Potential and current distribution in nerve: The effect of the nerve sheath, the number of fibers, and the frequency of alternating current stimulation (1955) (8)
Effects of K+, pH and glutamate on 45Ca kinetics in hippocampal brain slices (1995) (8)
The Dependency of Influx Across the Blood-Brain Barrier on Blood Flow and the Apparent Flow-Independence of Glucose Influx During Stress (1995) (8)
Imaging triiodothyronine binding kinetics in rat brain: A model for studies in human subjects (2006) (8)
Analysis of the distribution of materials within the blood-brain-cerebrospinal fluid system. (1967) (7)
Correlations between Plasminogen Activator Inhibitor-1 and Peritoneal Transport in Pediatric CCPD Patients (1995) (7)
Effects of Dexamethasone on the Blood-Brain Distribution of [125I] Albumin and [14C] Alpha-Aminoisobutyric Acid in Vasogenic Cerebral Edema (1985) (7)
Apparent glucose utilization in Walker 256 metastatic brain tumors (2005) (6)
Contribution of leaked load to solute transport by renal tubules. (1978) (6)
An approximation diffusion equation for a long narrow channel with varying cross-sectional area. (1973) (5)
Determination of regional blood-tissue transfer constants and initial (plasma) volume in brain and brain tumors using 68Ga-EDTA and dynamic positron emission tomography (1984) (5)
The uptake curve in tracer kinetics (1970) (5)
COMPARISON OF METHODS FOR DETERMINING BLOOD-BRAIN BARRIER PERMEABILITY (1975) (5)
A compartmental analysis of 24 Na kinetics in rat cerebrum, sciatic nerve and cerebrospinal fluid. (1972) (4)
Controversies Arising from Recent FDOPA Articles—Reply (1997) (4)
Use of transient and steady- state measurements of the unidirectional flux ratio for the determination of the free energy change of chemical reactions and active transport systems. (1980) (4)
The Effect of the Previous Generation on the Distribution of Gene Frequencies in Populations. (1953) (4)
Volume and ion regulation in both intracellular and extracellular compartments determined by diffusion, gravimetric and ion analysis. (1989) (4)
Freeze Lesion of the Cerebrum: Local Capillary Permeability, Blood Flow and Bulk Flow of Edema Fluid (1980) (3)
An Autoradiographic Study of Capillary Permeability during Hyperosmotic Opening (1980) (3)
Regulation of brain water during acute glucose-induced hyperosmolality in ovine fetuses, lambs, and adults. (2004) (3)
Contributions to the theory of active transport: III. The effect of drugs on active transport systems (1961) (2)
Book Review:Rstrip: Polyexponential Curve Stripping/Least Squares Parameter Estimation. (1992) (2)
An approximation diffusion equation for a long narrow channel with varying cross-sectional area (1973) (2)
Estimation of blood sampling errors resulting from metabolism and solute exchange between plasma and formed elements. (1994) (1)
Evaluation of [ 125 I]HIPDM as a Potential Tracer for Quantitative Measurement of Regional Cerebral Blood Flow (1985) (1)
[Effects of dehydration of the pituitary microcirculation in rats]. (1989) (1)
Kinetic and metabolic considerations in the use of (I-125) HIPDM as a tracer for quantitative measurement of regional cerebral blood flow (1984) (1)
A note on the two-factor theory with rectification as applied to alternating current stimulation. (1949) (1)
Apparent glucose utilization in Walker 256 metastatic brain tumors (2005) (1)
Cross-flow membrane plasmapheresis technique for continuous ex vivo plasma sampling. (1994) (1)
Effect of Postnatal Steroids on Blood-Brain Barrier Permeability in Newborn Lambs. † 1150 (1998) (1)
The Duration of Positive-Pressure Ventilation Influences Blood-Brain Barrier Function in Preterm Lambs 233 (1998) (1)
Fluid absorption and active and passive ion flows in the rabbit superficial pars recta. (2000) (1)
The blood-brain uptake of 3-O-methyl D-glucose may be mainly interstitial over times less than 45 seconds (2005) (0)
Effects of Antenatal Steroids on Blood-Brain Barrier Permeability in Early and Late Gestation Ovine Fetuses (1999) (0)
Cerebrovascular transport of ( sup 125 I)quinuclidinyl benzilate, ( sup 3 H)cyclofoxy, and ( sup 14 C)iodoantipyrine (1990) (0)
Quantitative analysis of microvessels in rat circumventricular organs and pituitary gland (1986) (0)
ANTENATAL STEROIDS DECREASE BLOOD-BRAIN BARRIER PERMEABILITY IN THE OVINE FETUS • 1067 (1997) (0)
Problems for Solution: E1446-E1449 (1961) (0)
Use of transient and steady-state measurements of the unidirectional flux ratio for the determination of the free energy change of chemical reactions and active transport systems (1980) (0)
Radiotracer Labeling of Brain Slices (2020) (0)
Clearance of monoamine metabolites during spinal subarachnoid perfusion (1975) (0)
Monoclonal antibody transport across tumor and systemic tissue (1985) (0)
Osmotic Transient Phenomenon (1974) (0)
Effects of Age and Endogenous Cortisol Concentrations on Blood-Brain Barrier Development in the Ovine Fetus (1999) (0)
The Effect of Duration of Positive-Pressure Ventilation on Blood-Brain Barrier Function in Premature Lambs (1999) (0)
Antenatal steroids decrease blood-brain barrier permeability in the ovine fetus. (1999) (0)
hyperosmolality in ovine fetuses, lambs, and adults Regulation of brain water during acute (2015) (0)
Effects of Pharmacological Dose of Dexamethasone Given Postnatally on Blood-Brain Barrier Permeability and Brain Water Content (2001) (0)
EFFECT OF ACUTE GLUCOSE-INDUCED HYPEROSMOLALITY ON BRAIN VOLUME REGULATION IN OVINE FETUSES, LAMBS AND ADULTS. † 382 (1996) (0)
The Author Replies (1983) (0)
Effect of Dexamethasone on Cerebrovascular Volume in Newborn Lambs (1999) (0)

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Published Works

What Schools Are Affiliated With Clifford S. Patlak?

Clifford S. Patlak's AcademicInfluence.com Rankings