Christopher Stanislaus Potten
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Biology
Christopher Stanislaus Potten's Degrees
- Masters Biochemistry University of Oxford
- Bachelors Biotechnology Imperial College London
Why Is Christopher Stanislaus Potten Influential?
(Suggest an Edit or Addition)Christopher Stanislaus Potten's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt. (1990) (1875)
- Intestinal stem cells protect their genome by selective segregation of template DNA strands. (2002) (677)
- Dissociation between steroid receptor expression and cell proliferation in the human breast. (1997) (664)
- The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. (1994) (621)
- The intestinal epithelial stem cell. (2002) (609)
- Stem cells in gastrointestinal epithelium: numbers, characteristics and death. (1998) (544)
- Identification of a putative intestinal stem cell and early lineage marker; musashi-1. (2003) (506)
- The intestinal epithelial stem cell: the mucosal governor (1997) (497)
- THE EPIDERMAL PROLIFERATIVE UNIT: THE POSSIBLE ROLE OF THE CENTRAL BASAL CELL (1974) (452)
- Epithelial stem cells in vivo (1988) (441)
- Accelerated Intestinal Epithelial Cell Turnover: A New Mechanism of Parasite Expulsion (2005) (407)
- Gut instincts: thoughts on intestinal epithelial stem cells. (2000) (389)
- Apoptosis and cancer chemotherapy. (1994) (366)
- Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality. (1998) (364)
- Stem cells: the intestinal stem cell as a paradigm. (2000) (329)
- Differential expression of bcl-2 in intestinal epithelia. Correlation with attenuation of apoptosis in colonic crypts and the incidence of colonic neoplasia. (1995) (326)
- A putative human breast stem cell population is enriched for steroid receptor-positive cells. (2005) (323)
- The segregation of DNA in epithelial stem cells (1978) (320)
- Cell migration and organization in the intestinal crypt using a lattice‐free model (2001) (298)
- Regulation and Significance of Apoptosis in the Stem Cells of the Gastrointestinal Epithelium (1997) (296)
- A comprehensive study of the radiobiological response of the murine (BDF1) small intestine. (1990) (279)
- Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast. (1999) (279)
- What is apoptosis, and why is it important? Education and debate (2001) (275)
- Highly persistent label-retaining cells in the hair follicles of mice and their fate following induction of anagen. (1999) (269)
- Response of intestinal cells of differing topographical and hierarchical status to ten cytotoxic drugs and five sources of radiation. (1983) (242)
- Apoptosis in small intestinal epithelia from p53-null mice: evidence for a delayed, p53-indepdendent G2/M-associated cell death after γ-irradiation (1997) (235)
- The relationship between ionizing radiation-induced apoptosis and stem cells in the small and large intestine. (1998) (233)
- Measurement of in vivo proliferation in human colorectal mucosa using bromodeoxyuridine. (1992) (229)
- Radiation, the Ideal Cytotoxic Agent for Studying the Cell Biology of Tissues such as the Small Intestine1 (2004) (227)
- The similarity of action spectra for thymine dimers in human epidermis and erythema suggests that DNA is the chromophore for erythema. (1998) (227)
- Slowly cycling (label‐retaining) epidermal cells behave like clonogenic stem cells in vitro (1994) (223)
- CONTINUOUS LABELLING STUDIES ON MOUSE SKIN AND INTESTINE (1974) (215)
- Identification of epithelial gaps in human small and large intestine by confocal endomicroscopy. (2007) (209)
- Epithelial cell growth and differentiation. II. Intestinal apoptosis. (1997) (205)
- Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbation. (1997) (203)
- Extreme sensitivity of some intestinal crypt cells to X and gamma irradiation. (1977) (199)
- Characterization of radiation-induced apoptosis in the small intestine and its biological implications. (1994) (198)
- Further studies on the response of intestinal crypt cells of different hierarchical status to eighteen different cytotoxic agents. (1987) (195)
- The significance of spontaneous and induced apoptosis in the gastrointestinal tract of mice (1992) (193)
- A comparison of cell replacement in bone marrow, testis and three regions of surface epithelium. (1979) (185)
- Perspectives on mammalian cell death. (1987) (182)
- Cell replacement in epidermis (keratopoiesis) via discrete units of proliferation. (1981) (179)
- The stem cells of small intestinal crypts: where are they? (2009) (177)
- A comprehensive model of the crypts of the small intestine of the mouse provides insight into the mechanisms of cell migration and the proliferation hierarchy. (1987) (165)
- Sensitivity to Sunburn Is Associated with Susceptibility to Ultraviolet Radiation–Induced Suppression of Cutaneous Cell–Mediated Immunity (2000) (164)
- Tumor Necrosis Factor α Is a Critical Component of Interleukin 13–Mediated Protective T Helper Cell Type 2 Responses during Helminth Infection (1999) (163)
- Topical treatment with liposomes containing T4 endonuclease V protects human skin in vivo from ultraviolet-induced upregulation of interleukin-10 and tumor necrosis factor-alpha. (2000) (162)
- 1 – Stem cells and cellular pedigrees – a conceptual introduction (1997) (162)
- Apoptosis, intrinsic radiosensitivity and prediction of radiotherapy response in cervical carcinoma. (1995) (157)
- Somatic mutation, monoclonality and stochastic models of stem cell organization in the intestinal crypt. (1993) (156)
- Keratinocyte Stem Cells: a Commentary1 (2002) (154)
- Caspase activation during spontaneous and radiation‐induced apoptosis in the murine intestine (2001) (149)
- Stimulation and inhibition of proliferation in the small intestinal crypts of the mouse after in vivo administration of growth factors. (1995) (146)
- The ordered columnar structure of mouse filiform papillae. (1976) (142)
- Proliferation in human gastrointestinal epithelium using bromodeoxyuridine in vivo: data for different sites, proximity to a tumour, and polyposis coli. (1992) (142)
- The in situ repair kinetics of epidermal thymine dimers and 6-4 photoproducts in human skin types I and II. (1996) (141)
- The temporal and spatial changes in cell proliferation within the irradiated crypts of the murine small intestine. (1990) (139)
- CIRCADIAN RHYTHMS OF PRESUMPTIVE STEM CELLS IN THREE DIFFERENT EPITHELIA OF THE MOUSE (1977) (131)
- Regulation of human breast epithelial stem cells (2003) (130)
- The relationships between p53-dependent apoptosis, inhibition of proliferation, and 5-fluorouracil-induced histopathology in murine intestinal epithelia. (1998) (129)
- Oral contraceptive (OCP) use increases proliferation and decreases oestrogen receptor content of epithelial cells in the normal human breast (1991) (128)
- Age changes in stem cells of murine small intestinal crypts. (1998) (127)
- Repeated ultraviolet exposure affords the same protection against DNA photodamage and erythema in human skin types II and IV but is associated with faster DNA repair in skin type IV. (2002) (126)
- Epidermal cell production rates. (1975) (122)
- Evidence for discrete cell kinetic subpopulations in mouse epidermis based on mathematical analysis (1982) (121)
- The detection of cyclobutane thymine dimers, (6-4) photolesions and the Dewar photoisomers in sections of UV-irradiated human skin using specific antibodies, and the demonstration of depth penetration effects. (1995) (118)
- Interleukin‐11 protects the clonogenic stem cells in murine small‐intestinal crypts from impairment of their reproductive capacity by radiation (1995) (118)
- Human melanocytes and keratinocytes exposed to UVB or UVA in vivo show comparable levels of thymine dimers. (1998) (117)
- Altered stem cell regeneration in irradiated intestinal crypts of senescent mice. (1998) (116)
- The small intestine as a model for evaluating adult tissue stem cell drug targets 1 (2003) (113)
- Elevated serum insulin-like growth factor (IGF)-II and IGF binding protein-2 in patients with colorectal cancer (2000) (113)
- Damage-induced apoptosis in intestinal epithelia from bcl-2-null and bax-null mice: investigations of the mechanistic determinants of epithelial apoptosis in vivo (1999) (111)
- Keratinocyte stem cells: a commentary. (2002) (111)
- Acromegaly and colorectal cancer: a comprehensive review of epidemiology, biological mechanisms, and clinical implications. (2003) (111)
- Cell death (apoptosis) in the mouse small intestine after low doses: effects of dose-rate, 14.7 MeV neutrons, and 600 MeV (maximum energy) neutrons. (1982) (110)
- β7 integrin‐deficient mice: delayed leukocyte recruitment and attenuated protective immunity in the small intestine during enteric helminth infection (2000) (106)
- Cell Migration Velocities In the Crypts of the Small Intestine After Cytotoxic Insult Are Not Dependent On Mitotic Activity (1986) (104)
- A model of the control of cellular regeneration in the intestinal crypt after perturbation based solely on local stem cell regulation (1992) (103)
- Clonogenic Cells and Stem Cells in Epidermis (1973) (102)
- Radiation-induced p53 and p21WAF-1/CIP1 expression in the murine intestinal epithelium: apoptosis and cell cycle arrest. (1998) (101)
- Effect of epidermal growth factor receptor tyrosine kinase inhibition on epithelial proliferation in normal and premalignant breast. (2002) (99)
- Pretreatment with transforming growth factor beta-3 protects small intestinal stem cells against radiation damage in vivo. (1997) (98)
- The role of radiation-induced and spontaneous apoptosis in the homeostasis of the gastrointestinal epithelium: a brief review. (1997) (98)
- Cell cycles in cell hierarchies. (1986) (97)
- Differential regeneration of intestinal proliferative cells and cryptogenic cells after irradiation. (1975) (95)
- Clonality and life cycles of intestinal crypts explained by a state dependent stochastic model of epithelial stem cell organization. (1997) (94)
- Trichuris muris: host intestinal epithelial cell hyperproliferation during chronic infection is regulated by interferon-gamma. (1999) (94)
- Isoflavones inhibit intestinal epithelial cell proliferation and induce apoptosis in vitro (1999) (94)
- Protection of the Small Intestinal Clonogenic Stem Cells from Radiation‐Induced Damage by Pretreatment with Interleukin 11 also Increases Murine Survival Time (1996) (92)
- The differentiation and lineage development of goblet cells in the murine small intestinal crypt: experimental and modelling studies. (1993) (90)
- High‐risk colorectal adenomas and serum insulin‐like growth factors (2001) (88)
- Protection against mucosal injury by growth factors and cytokines. (2001) (88)
- Protection by ultraviolet A and B sunscreens against in situ dipyrimidine photolesions in human epidermis is comparable to protection against sunburn. (2000) (83)
- Transforming growth factor‐β3 protects murine small intestinal crypt stem cells and animal survival after irradiation, possibly by reducing stem‐cell cycling (2000) (82)
- Circulating insulin-like growth factor II and colorectal adenomas. (2000) (79)
- Tanning salon exposure and molecular alterations. (2001) (78)
- The gastrointestinal syndrome and mucosal clonogenic cells: relationships between target cell sensitivities, LD50 and cell survival, and their modification by antibiotics. (1983) (78)
- Tanning in Human Skin Types II and III Offers Modest Photoprotection Against Erythema (1998) (78)
- Bcl-w is an important determinant of damage-induced apoptosis in epithelia of small and large intestine (2000) (77)
- Regeneration and dose-response characteristics of irradiated mouse dorsal epidermal cells. (1976) (75)
- Cryptogenic cells and proliferative cells in intestinal epithelium. (1974) (74)
- Intestinal cell radiosensitivity: a comparison for cell death assayed by apoptosis or by a loss of clonogenicity. (1982) (73)
- Double Labelling With Bromodeoxyuridine and (3H)‐Thymidine of Proliferative Cells In Small Intestinal Epithelium In Steady State and After Irradiation (1988) (71)
- The number of clonogenic cells in crypts in three regions of murine large intestine. (1997) (70)
- Advances in epithelial kinetics--an oral view. (1979) (69)
- Photoprotection and 5-MOP photochemoprotection from UVR-induced DNA damage in humans: the role of skin type. (1991) (68)
- Early cellular events in colorectal carcinogenesis (2002) (67)
- Maintenance of functional stem cells in isolated and cultured adult intestinal epithelium. (1999) (66)
- The relevance of apoptosis for cellular homeostasis and tumorigenesis in the intestine. (2001) (66)
- Cell clones : manual of mammalian cell techniques (1985) (66)
- The isolation and culture of adult mouse colonic epithelium. (1995) (64)
- The crypt cycle in mouse small intestinal epithelium. (1994) (63)
- Enzyme therapy of xeroderma pigmentosum: safety and efficacy testing of T4N5 liposome lotion containing a prokaryotic DNA repair enzyme (1996) (63)
- Radiation and gut (1995) (61)
- Stem cells and tissue homeostasis (1978) (60)
- Pathbase: a database of mutant mouse pathology (2004) (60)
- Epidermal transit times (1975) (60)
- The effects of repeated doses of keratinocyte growth factor on cell proliferation in the cellular hierarchy of the crypts of the murine small intestine. (2001) (60)
- The spatial organization of the hierarchical proliferative cells of the crypts of the small intestine into clusters of ‘synchronized’ cells (1982) (60)
- Cell migration in the small and large bowel shows a strong circadian rhythm. (1994) (58)
- Estimates of the number of clonogenic cells in crypts of murine small intestine (1987) (58)
- Characterization of putative stem cells in isolated human colonic crypt epithelial cells and their interactions with myofibroblasts. (2009) (58)
- Apoptosis as predictor of response to radiotherapy in cervical carcinoma (1994) (57)
- The correction of intestinal microcolony counts for variation in size. (1981) (57)
- Deduction of the clonogen content of intestinal crypts: a direct comparison of two-dose and multiple-dose methodologies. (1995) (57)
- Keratinocyte stem cells, label-retaining cells and possible genome protection mechanisms. (2004) (57)
- Cell cycle kinetics of cultured human epidermal keratinocytes. (1983) (56)
- Measurement of the transit time for cells through the epidermis and stratum corneum of the mouse and guinea‐pig (1987) (56)
- Epithelial proliferation and hormone receptor status in the normal post-menopausal breast and the effects of hormone replacement therapy. (1998) (56)
- Circadian Variation In Migration Velocity In Small Intestinal Epithelium (1986) (55)
- 1,2-Dimethylhydrazine-induced colon carcinoma and lymphoma in msh2(-/-) mice. (2001) (54)
- The circadian rhythm for the number and sensitivity of radiation-induced apoptosis in the crypts of mouse small intestine. (1990) (54)
- Apoptosis induced by high- and low-LET radiations (1995) (53)
- The clonogen content of murine intestinal crypts: dependence on radiation dose used in its determination. (1992) (53)
- p53 deficiency sensitizes clonogenic cells to irradiation in the large but not the small intestine. (1997) (52)
- DNA damage in UV-irradiated human skin in vivo: automated direct measurement by image analysis (thymine dimers) compared with indirect measurement (unscheduled DNA synthesis) and protection by 5-methoxypsoralen. (1993) (52)
- An Increase in Epithelial Cell Apoptosis Is Associated with Chronic Intestinal Nematode Infection (2007) (51)
- Poly(ADP-ribose) polymerase-1 is a survival factor for radiation-exposed intestinal epithelial stem cells in vivo. (2003) (50)
- Assessment of hormone dependence of comedo ductal carcinoma in situ of the breast. (1997) (50)
- Effects of IL‐11 on the growth of intestinal epithelial cells in vitro (1995) (50)
- Differential Radiation Response Amongst Proliferating Epithelial Cells (1978) (49)
- HIV enteropathy: crypt stem and transit cell hyperproliferation induces villous atrophy in HIV/Microsporidia-infected jejunal mucosa (2007) (48)
- Inhibition of doxorubicin-induced apoptosis in vivo by 2-deoxy-D-glucose. (1993) (47)
- Mapping dynamic epithelial cell proliferative activity within the oral cavity of man: a new insight into carcinogenesis? (1999) (47)
- A comparison of in vivo cell proliferation measurements in the intestine of mouse and man. (1992) (46)
- Identification of Clonogenic Cells in the Epidermis and the Structural Arrangement of the Epidermal Proliferative Unit (EPU) (1976) (46)
- Radiation and skin (1985) (45)
- Circadian Rhythms In the Epithelial Cells and the Pericryptal Fibroblast Sheath In Three Different Sites In the Murine Intestinal Tract (1981) (45)
- Ageing of murine small intestinal stem cells. (2001) (44)
- Epidermal cell proliferation (1987) (44)
- Pyrrolidinedithiocarbamate increases the therapeutic index of 5-fluorouracil in a mouse model. (2000) (44)
- Effects of glycosaminoglycans on proliferation of epithelial and fibroblast human malignant mesothelioma cells: a structure–function relationship (1999) (43)
- Differential survival of murine small and large intestinal crypts following ionizing radiation. (1997) (43)
- Cytotoxic insult to tissue : effects on cell lineages (1983) (42)
- Abrogation of adriamycin toxicity in vivo by cycloheximide. (1992) (41)
- Gamma-ray-induced cell killing and chromosome abnormalities in the bone marrow of p53-deficient mice. (1996) (40)
- HIV enteropathy: HAART reduces HIV-induced stem cell hyperproliferation and crypt hypertrophy to normal in jejunal mucosa (2013) (40)
- An Introduction to Cell Population Kinetics (1978) (39)
- Evidence of significant apoptosis in poorly differentiated ductal carcinoma in situ of the breast. (1998) (39)
- Crowd control in the crypt (2002) (38)
- Biological Effects of Ultraviolet Radiation with Emphasis on Human Responses to Longwave Ultraviolet (1980) (38)
- Circadian rhythms in the incidence of apoptotic cells and number of clonogenic cells in intestinal crypts after radiation using normal and reversed light conditions. (1988) (38)
- RADIATION DEPIGMENTATION OF MOUSE HAIR: A STUDY OF FOLLICULAR MELANOCYTE POPULATIONS (1968) (37)
- The doubling time of regenerating clonogenic cells in the crypts of the irradiated mouse small intestine. (1988) (37)
- Description and basic cell kinetics of the murine pericryptal fibroblast sheath. (1981) (36)
- INCORPORATION OF TRITIATED THYMIDINE INTO THE SKIN AND HAIR FOLLICLES (1971) (35)
- P53 deficiency produces fewer regenerating spermatogenic tubules after irradiation. (1996) (35)
- Heterogeneity and cell cycle analyses from time-lapse studies of human keratinocytes in vitro. (1988) (35)
- Tritiated thymidine incorporation into hair follicle matrix and epidermal basal cells after stimulation. (1971) (34)
- Effects of a pure antiestrogen on apoptosis and proliferation within human breast ductal carcinoma in situ. (2000) (34)
- The effect of exogenous prostaglandin administration on tumor size and yield in Min/+ mice. (2000) (34)
- Stem cells : their identification and characterisation (1983) (34)
- Clonogen content of intestinal crypts: its deduction using a microcolony assay on whole mount preparations and its dependence on radiation dose. (1994) (33)
- Radiation-induced mitotic delay: duration, dose and cell position dependence in the crypts of the small intestine in the mouse. (1986) (33)
- The cell kinetic mechanism for radiation-induced cellular depletion of epithelial tissue based on hierarchical differences in radiosensitivity. (1981) (33)
- The recruitability and cell-cycle state of intestinal stem cells. (1984) (33)
- THE ACTION SPECTRUM FOR INDUCTION OF CHRONIC ACTINIC DERMATITIS IS SIMILAR TO THAT FOR SUNBURN INFLAMMATION (1995) (33)
- Kinetics and possible regulation of crypt cell populations under normal and stress conditions. (1975) (32)
- Inhibition of UV radiation-induced DNA damage by a 5-methoxypsoralen tan in human skin. (1988) (32)
- Cell death (apoptosis) in hair follicles and consequent changes in the width of hairs after irradiation of growing follicles. (1985) (32)
- Keratinocyte growth factor increases hair follicle survival following cytotoxic insult. (2000) (31)
- STEM CELLS VERSUS STEM LINES (1982) (31)
- Cell kinetic studies in the murine ventral tongue epithelium: thymidine metabolism studies and circadian rhythm determination (2002) (31)
- Intestinal crypt clonogens: a new interpretation of radiation survival curve shape and clonogenic cell number (2003) (30)
- The response of murine intestinal crypts to short-range promethium-147 beta irradiation: deductions concerning clonogenic cell numbers and positions. (1989) (29)
- Changes after irradiation in the number of mitotic cells and apoptotic fragments in growing mouse hair follicles and in the width of their hairs. (1990) (29)
- Purine nucleotides modulate proliferation of brown fat preadipocytes (1999) (29)
- Regeneration in epithelial proliferative units as exemplified by small intestinal crypts. (2007) (28)
- Tumour stem cells: the relevance of predictive assays for tumour control after radiotherapy. (1994) (28)
- A long‐lived thymidine pool in epithelial stem cells (1982) (28)
- Effects of Puromycin, Cycloheximide and Noradrenaline On Cell Migration Within the Crypts and On the Villi of the Small Intestine (1986) (27)
- A CELL KINETIC MODEL TO EXPLAIN THE TIME OF APPEARANCE OF SKIN REACTION AFTER X‐RAYS OR ULTRAVIOLET LIGHT IRRADIATION (1979) (27)
- The re-establishment of hypersensitive cells in the crypts of irradiated mouse intestine. (1984) (26)
- Crypt base columnar cells in ileum of BDF1 male mice--their numbers and some features of their proliferation. (1989) (26)
- Apoptosis in oral mucosa: lessons from the crypt. A commentary. (2001) (26)
- Growth factor regulation of proliferation in primary cultures of small intestinal epithelium (1995) (26)
- Recruitment of Cells in the Small Intestine into Rapid Cell Cycle by Small Doses of External γ or Internal β-radiation (1985) (26)
- Chemically-induced apoptosis: p21 and p53 as determinants of enterotoxin activity. (1998) (26)
- The interfollicular epidermal stem cell saga: sensationalism versus reality check (2011) (26)
- The radiosensitivity of cultured human and mouse keratinocytes. (1986) (26)
- The c‐myc gene regulates the polyamine pathway in DMSO‐induced apoptosis. (1999) (24)
- P27(KIP1) expression indicates that steroid receptor-positive cells are a non-proliferating, differentiated subpopulation of the normal human breast epithelium. (2000) (24)
- The Gastrointestinal Subsyndrome of the Acute Radiation Syndrome in Rhesus Macaques: A Systematic Review of the Lethal Dose-response Relationship With and Without Medical Management (2019) (24)
- Sombe observations on the post-plucking depression in tritiated thymidine utilization in mouse skin and some tentative cell kinetic determinations. (1972) (24)
- EARLY AND LATE INCORPORATION OF TRITIATED THYMIDINE INTO SKIN CELLS AND THE PRESENCE OF A LONG-LIVED G0-SPECIFIC PRECURSOR POOL (1971) (23)
- Heterogeneity in histone 2B-green fluorescent protein-retaining putative small intestinal stem cells at cell position 4 and their absence in the colon. (2012) (23)
- Study of the proliferation in human gastric mucosa after in vivo bromodeoxyuridine labelling. (1993) (23)
- INCORPORATION OF TRITIATED THYMIDINE INTO THE SKIN AND HAIR FOLLICLES (1971) (23)
- Radiation-hypersensitive cells in small intestinal crypts; their relationships to clonogenic cells. (1986) (22)
- Clonogenic, stem and carcinogen-target cells in small intestine. (1984) (22)
- FURTHER OBSERVATIONS ON THE LATE LABELLING ASSOCIATED WITH STIMULUS‐RESPONSIVE CELLS IN SKIN (1973) (22)
- Apoptosis: The Life and Death of Cells (2004) (21)
- Epithelial stem cell‐related alterations in Trichinella spiralis‐infected small intestine (2009) (21)
- Epidermal p53 response and repair of thymine dimers in human skin after a single dose of ultraviolet radiation: effects of photoprotection. (2001) (20)
- Cell kinetic studies in the epidermis of the mouse. I. Changes in labeling index with time after tritiated thymidine administration (1983) (20)
- A quantitative histometric murine in vivo model of radiation-induced oral mucositis. (1998) (20)
- Repeated injection (continuous labelling) experiments in mouse epidermis. (1980) (20)
- Cell kinetic studies in murine ventral tongue epithelium: cell cycle progression studies using double labelling techniques (2002) (19)
- Tritiated thymidine and bromodeoxyuridine double-labelling studies on growth factors and oral epithelial proliferation in the mouse. (1999) (19)
- Age‐Related Changes in Irradiation‐Induced Apoptosis and Expression of p21 and p53 in Crypt Stem Cells of Murine Intestine (2000) (19)
- Characterization of epithelial cell activity in patients with oral cancer. (1999) (19)
- Radiation effects on proliferation and differentiation in the rat small intestine. (1995) (19)
- Letter: Clonogenic cells and stem cells in epidermis. (1973) (19)
- Radiation depigmentation of mouse hair: the influence of local tissue oxygen tension on radiosensitivity. (1969) (19)
- Effect of bcl-2 deficiency on the radiation response of clonogenic cells in small and large intestine, bone marrow and testis. (2000) (18)
- The Proliferative Status of Microcolony‐Forming Cells In Mouse Small Intestine (1984) (18)
- Helicobacter pylori regulates the expression of inhibitors of DNA binding (Id) proteins by gastric epithelial cells. (2006) (18)
- Small Intestinal Crypt Stem Cells (1976) (18)
- A critical assessment of the intestinal proliferon hypothesis. (1981) (17)
- Radiation depigmentation of mouse hair: split-dose experiments and melanocyte precursors (amelanotic melanoblasts) in the resting hair follicle. (1970) (17)
- In vitro labelling studies and the measurement of epithelial cell proliferative activity in the human oral cavity. (2001) (17)
- Response of human hair cortical cells to fractionated radiotherapy. (1997) (16)
- The role of stem cells in the regeneration of intestinal crypts after cytotoxic exposure. (1991) (16)
- Effect of low dose ionizing radiation on the murine pericryptal fibroblast sheath: radiation damage in a mesenchymal system in vivo. (1981) (16)
- Tissue Stem cells: Biology and Applications (2006) (16)
- A topographical study of the circadian rhythm in labelling index of mouse gingival and floor-of-mouth epithelium, including changes in labelling activity with individual cell position on the epithelial ridges. (1989) (15)
- Changes in the cellularity of the cortex of human hairs as an indicator of radiation exposure (1996) (15)
- Regional differences in stem and transit cell proliferation and apoptosis in the terminal ileum and colon of mice after 12 Gy. (2012) (15)
- MIGRATION AND MITOSIS IN THE EPIDERMIS (1984) (15)
- Hair medullary cell counts: a simple and sensitive indicator of radiation exposure. (1990) (14)
- The radiosensitivity of hair follicles in mouse dorsum and tail. (1980) (14)
- The effect of repeated plucking on mouse skin cell kinetics. (1974) (14)
- Small intestinal growth regulatory factors extracted by simple diffusion from intact irradiated intestine and tested in vivo. (1994) (14)
- Tissue Stem Cells (2006) (14)
- Radiation depigmentation of mouse hair: effect of the hair growth cycle on the sensitivity. (1970) (13)
- Adult small intestinal stem cells: identification, location, characteristics, and clinical applications. (2006) (13)
- The antioxidant n-acetylcysteine increases 5-fluorouracil activity against colorectal cancer xenografts in nude mice (2001) (13)
- Expression of pokeweed lectin binding in murine intestinal Paneth cells. (1994) (13)
- The role of the E‐cadherin complex in gastrointestinal cell differentiation (1999) (12)
- Cell kinetics in rat small intestine after exposure to 3 Gy of gamma-rays at different times of the day. (1996) (12)
- Proliferation in murine epidermis after minor mechanical stimulation Part 2. Alterations in keratinocyte cell cycle fluxes (2000) (11)
- In vivo administration of genistein has no effect on small intestinal epithelial proliferation and apoptosis, but a modest effect on clonogen survival. (1999) (11)
- Recruitment of cells in the small intestine into rapid cell cycle by small doses of external gamma or internal beta-radiation. (1985) (11)
- Effect of photoreactivating light on UV radiation-induced alterations in human skin (2001) (10)
- Association of pS2 (TFF1) release with breast tumour proliferative rate: in vitro and in vivo studies (1999) (10)
- Radiosensitivity of normal human epidermal cells in culture. (1983) (10)
- The importance of p53-independent apoptosis in the intestinal toxicity induced by raltitrexed (ZD1694, Tomudex): genetic differences between BALB/c and DBA/2 mice. (2000) (10)
- The Intestine as a Model for Studying Stem-Cell Behavior (2002) (10)
- The cellular basis of skin injury after cytotoxic insult. (1986) (9)
- A potent stimulator of small intestinal cell proliferation extracted by simple diffusion from intact irradiated intestine: in vitro studies. (1994) (9)
- Apoptosis Genes (1998) (9)
- Differential influence of TGFbeta1 and TGFbeta3 isoforms on cell cycle kinetics and postirradiation recovery of normal and malignant colorectal epithelial cells. (1997) (9)
- RADIATION DEPIGMENTATION OF MOUSE HAIR: EFFECTS OF MOUSE STRAIN (1969) (9)
- Apoptosis Genes (1998) (9)
- Cell Position Dependence of Labelling Thymidine Nucleotides Using the De Novo and Salvage Pathways In the Crypt of Small Intestine (1986) (9)
- Alpha/beta ratios and the cycling status of tissue target cells. (1988) (8)
- Distribution and morphology of UV-induced epidermal cell death (1977) (8)
- LABELING OF MURINE MASTOCYTOMA CELLS IN VITRO WITH PLASMA TRITIATED THYMIDINE-LABELED ANIMALS (1971) (8)
- Some observations on melanin synthesis anomalies in mouse hair follicles after treatment with x-rays or actinomycin D. (1972) (7)
- Ultrastructural changes in mouse hair follicle pigment cells after plucking, x-rays, and actinomycin D treatment. (1971) (7)
- FIXATIVE‐SOLUBLE TRITIUM POOL SIZE AFTER TRITIATED THYMIDINE INJECTION INTO MICE WITH SKIN STIMULATED BY PLUCKING (1971) (7)
- CELL KINETICS IN THE SEBACEOUS GLANDS OF THE MOUSE. II. THE GLANDS DURING HAIR GROWTH (1974) (7)
- Lipid‐induced changes in vascular smooth muscle cell membrane fluidity are associated with DNA synthesis (1999) (7)
- Analysis of the Changes In the Proportion of Clustered Labelled Cells In Epidermis (1986) (7)
- Chapter Thirty-One – Adult Epithelial Tissue Stem Cells (2007) (7)
- Accelerated repopulation of intestine post-irradiation following intraluminal injection of a mucosal cell suspension or its supernatant. (1993) (7)
- Cyclical Activity and ‘Ageing’ of the Human Breast: Clues to Assessment of Risk and Strategies for Prevention (1994) (6)
- Proliferative Cell Populations in Surface Epithelia: Biological Models for Cell Replacement (1980) (6)
- Effects of deficiency in p53 or bcl-2 on the sensitivity of clonogenic cells in the small intestine to low dose-rate irradiation. (2000) (6)
- Biological effectiveness of high-energy protons. (1969) (6)
- Small intestinal cryptogenic cells in W/Wv mutant mice. (1978) (5)
- Salaries of Research Workers (1975) (5)
- Endothelial Cells and Radiation Gastrointestinal Syndrome (2001) (5)
- Influence of irradiation or thymidine (TdR) on the pattern of 3H-TdR incorporation at each cell position in the crypts of the small intestine of the mouse. (1987) (5)
- Immunohistochemical localization of BAX and BAD in the normal and BCL-2 null gastrointestinal tract (1996) (5)
- Hair cortical cell counts (HCCC), a new sensitive in vivo assay with possible applications for biological dosimetry. (1993) (5)
- Cell Turnover: Intestine and Other Tissues (2005) (5)
- Hair medullary cell counts following low-dose-rate γ- and high-energy neutron irradiation (1993) (5)
- Biological dosimetry of local radiation accidents of skin: possible cytological and biochemical methods. (1986) (5)
- No apoptotic endothelial cells in irradiated intestine: regarding Schuller et al. (Int J Radiat Oncol Biol Phys 2007;68:205-210). (2008) (5)
- ALX-0600, a glucagon-like peptide-2 analogue, protects small intestinal stem cells from radiation damage (2003) (4)
- Regional localisation of p53-independent apoptosis determines toxicity to 5-fluorouracil and pyrrolidinedithiocarbamate in the murine gut (2006) (4)
- Modelling of the influence of 3HTdR on cell kinetics in mouse epidermis (1987) (4)
- Pigment abnormalities in irradiated hair follicles: effects of low doses, dose rate, and LET. (1981) (4)
- The decay of autoradiographic grain number over crypt base columnar cells in murine ileum as a measure of their generation time (1991) (4)
- Pigment clumping in growing hair follicles of mice. A sensitive radiobiological model. (1972) (4)
- Wavelength Dependence for DNA Photodamage in Human Skin In Vivo (2000) (3)
- The radiosensitivity of keratinocytes from tongue and skin; enhanced radioresistance following serial cultivation (1986) (3)
- Epidermal DNA Repair Under Repeated Exposure Conditions is Complex (2002) (3)
- CELL MAINTENANCE AND STRESS RESPONSE IN AGEING AND LONGEVITY (1996) (3)
- Apoptosis induced in small intestinal crypts by low doses of radiation protects the epithelium from genotoxic damage (2002) (3)
- Epithelia of the mouse. (1977) (3)
- Cell-position-dependent mitotic inhibition in the crypt of the small intestine following irradiation (1986) (2)
- Sensitivity of follicular melanoblasts in newborn mouse skin to tritiated thymidine: Evidence for a long term retention of label (1982) (2)
- 63. Comedo DCIS is hormone independent and will not benefit from antioestrogen therapy (1995) (2)
- 0-47. Epithelial proliferation and hormone receptor status in the normal postmenopausal breast and the effects of HRT use (1997) (2)
- The Development of Epithelial Stem Cell Concepts (2014) (2)
- Phase II study of T4N5 liposome lotion for the treatment of xeroderma pigmentosum. (1995) (1)
- Repair of cyclobutyl pyrimidine dimers in skin cancer patients treated with liposomes containing T4 endonuclease V (1998) (1)
- Chapter 39 – The Development of Epithelial Stem Cell Concepts (2013) (1)
- Introduction: Epithelial stem cells. Part II. Intestinal Mucosa (1993) (1)
- Variation in tritiated thymidine uptake and incorporation into murine epidermis throughout the day and throughout the year: Evidence for a four‐monthly cycle (1987) (1)
- Hair is a viable surrogate tissue for routine measurement of gene expression in clinical studies (2007) (1)
- The Importance of Spontaneous and Radiation Induced Apoptosis for Stem Cells in the Gastrointestinal Tract (1999) (1)
- Immunolocalization of EGF receptor (EGFr) in intestinal epithelium: recognition of apoptotic cells (1996) (1)
- Comments on the paper: Cell survival in irradiated microcolonies: how influential are the neighbours? (1998) (1)
- Lack of correlation between epidermal basal cell survival and probability of healing of skin reactions in swine. (1985) (1)
- Oestrogen withdrawal reduces epithelial cell proliferation in oestrogen receptor (ER) positive but not negative ductal carcinoma in-situ (DCIS) (2001) (1)
- Radiation depigmentation of hair, dose-rsponse relationship for follicular melanocyte precursors. Abstr. (1968) (1)
- 167b Apoptosis, intrinsic radiosensitivity and prediction of radiotherapy response in cervical carcinoma (1995) (1)
- Stem cell vs. stem lines (1983) (0)
- Chalones: edited by John C. Houck, published by North-Holland/American Elsevier, Amsterdam, New York, 1976. Dfl.165.-($63.50) (xiii+510 pages) (1976) (0)
- Dramatic Type of Reprogramming Is Suggested Mammalian Neural Stem Cells (0)
- Protective effect of growth factors against intestinal radiation syndrome. (1999) (0)
- DNA Photodamage and its Repair in Human Epidermis In Vivo (1996) (0)
- Corrigendum to “Chemically-induced apoptosis: p21 and p53 as determinants of enterotoxin activity” [Toxicol. Lett. 102–103C (1998) 19–27] (2012) (0)
- Jane Mathematical Modeling of Stem Cells : A Complexity Primer for the Stem-Cell Biologist (2014) (0)
- Sharpening the focus; the business of epithelial cell biology. An interview with Chris Potten by David Pearton. (2004) (0)
- Oxygen supply to mouse hair follicles. Radiation inactivation of melanocytes. (1966) (0)
- Editorial (1991) (0)
- BCL-W expression is an important determinant of damage-induced apoptosis in murine small and large intestinal epithelium in vivo (2000) (0)
- Review article : Modelling of the influence of 3HTdR on cell kinetics in mouse epidermis (1989) (0)
- Proliferation, Spread and Reaction-Dispersal Processes (1980) (0)
- Cell and Tissue Organisation (2005) (0)
- Protective effect of TGFß3 on the irradiated small instestine of mice. (1997) (0)
- BookBook ReviewChalones, John C. Houck (Ed.), North-Holland/American Elsevier, London and Winchester (1976) (1976) (0)
- Radiation depigmentation of mouse hair, variation in sensitivity with genotype and hair growth cycle. Abstr. (1967) (0)
- Control device and method for a quick-closing valve of a steam turbine (2008) (0)
- T1748 Comparative Studies of Label-Retaining Epithelial Cells in the Small and Large Intestine: Implications for the Concept of Asymmetric Stem Cell Division in the Colon (2010) (0)
- Chapter 3 – The Development of Epithelial Stem Cell Concepts (2009) (0)
- Studies with iressa, a novel EGF receptor tyrosine kinase inhibitor on breast cancer cells and in situ cancer “in vivo” (2001) (0)
- Keratinocyte Growth Factor Protects Mice from Chemotherapy and Radiation-induced Gastrointestinal Injury and Mortality 1 (1998) (0)
- Insulin-like Growth Factor (IGF)-II Peptide Overexpression Early in the Adenoma-Carcinoma Sequence. (2001) (0)
- The antioxidant N-acetylcysteine modulates 5-Fluorouracil activity against colorectal cancer xenografts in nude mice (2000) (0)
- Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast 1–3 (1999) (0)
- 5-MOP Induced Protection Against Epidermal DNA Damage by Ultraviolet Radiation in Human Skin: The Role of the Skin Type (1991) (0)
- COX-1, COX-2 and β-Catenin in the gut. An immunohistochemical study (1999) (0)
- 5-MOP induced protection against epidermal DNA damage by ultraviolet radiation in human skin. (1990) (0)
- 0-18. Antioestrogen therapy does not affect apoptosis or mitosis in comedo ductal carcinoma in situ (DCIS) (1997) (0)
- Editorial (2002) (0)
- M1622 Investigation of Intestinal Epithelial Stem Cell Function Under Basal Conditions and Following Irradiation (2009) (0)
- Radioprotective effects of growth factors in the gastrointestinal epithelium. (2000) (0)
- 16th Paterson Symposium—Cellular mechanisms of long-term injury in tissue after radiation (1982) (0)
- Pyrrolidineditidocarbamate enhances the P53 independent apoptosis induced by 5-FU (2000) (0)
- Hair medullary cell counts following low-dose-rate gamma- and high-energy neutron irradiation. (1993) (0)
- Two-Week Dietary Soy Supplementation Has an Estrogenic Effect on Normal Premenopausal Breast (2000) (0)
- Review Series: Hyperthermia (1992) (0)
- Growth Kinetics and Regulation of Normal and Malignant Cells (1978) (0)
- Meetings Announcements Joint Meeting of the Association for Radiation Research and the Netherlands Radiobiological Society (1985) (0)
- OC-040 Comparative studies of label-retaining epithelial cells in the small and large intestine: implications for the concept of asymmetric stem cell division in the colon (2010) (0)
- 909a Doxycycline-Induced Histone 2B (H2B)-Green Fluorescent Protein (GFP)-Retaining Putative Stem Cells Participate in Small Intestinal Regeneration, but are Absent in the Colon (2012) (0)
- Proliferative cell populations in surface epithelia (1980) (0)
- Radiation depigmentation of mouse hair, the dose-response relation- ship for follicular melanocyte presursors. Abstr. (1967) (0)
- Radiation depigmentation of mouse hair, recovery between split doses. Abstr. (1967) (0)
- Introduction: Epithelial stem cells. Part I. Keratinocytes (1993) (0)
- Tenth Paterson Symposium (1976) (0)
- Apoptosis in the normal and malignant colon (2001) (0)
- Pyrrolidinedithiocarbamate (PDTC) reduces the cytotoxic action of 5-fluorouracil in normal murine small intestine: The roles of P53, P21 and C/EPBβ (1998) (0)
- Stem cells and cancer. (2008) (0)
- Obituary: Professor Christopher Stanislaus Potten BSc, PhD, DSc 1940-2012. (2014) (0)
- The Importance of p 53-Independent Apoptosis in the Intestinal Toxicity Induced by Raltitrexed ( ZD 1694 , Tomudex ) : Genetic Differences between BALB / c and DBA / 2 Mice 1 (2000) (0)
- Serum and nipple aspirate levels of vitamin A and vitamin E and lack of an association with breast cancer (1998) (0)
- Editorial (1988) (0)
- The intestinal proliferon hypothesis. (1982) (0)
- [Cell number in the medullary substance of hair: a simple and sensitive indicator of exposure to radiation]. (1991) (0)
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