Carl T. Brighton

Carl T. Brighton's AcademicInfluence.com Rankings

Carl T. Brighton

Philosophy

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#5784

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Carl T. Brighton

Biology

#10096

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#13389

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Cell Biology

#463

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#474

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Philosophy
Biology

Carl T. Brighton's Degrees

Doctorate Medicine Stanford University

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Carl T. Brighton's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The pericyte as a possible osteoblast progenitor cell. (1992) (297)
Signal Transduction in Electrically Stimulated Bone Cells (2001) (263)
A multicenter study of the treatment of non-union with constant direct current. (1981) (257)
Shear strength of the human femoral capital epiphyseal plate. (1976) (251)
Bioelectric potentials in bone. (1966) (251)
Oxygen tension in zones of the epiphyseal plate, the metaphysis and diaphysis. An in vitro and in vivo study in rats and rabbits. (1971) (249)
Oxygen tension of healing fractures in the rabbit. (1972) (234)
Real‐Time Calcium Response of Cultured Bone Cells to Fluid Flow (1995) (218)
Electrical stimulation induces the level of TGF-beta1 mRNA in osteoblastic cells by a mechanism involving calcium/calmodulin pathway. (1997) (205)
The proliferative and synthetic response of isolated calvarial bone cells of rats to cyclic biaxial mechanical strain. (1991) (200)
Intracellular Ca2+ stores and extracellular Ca2+ are required in the real-time Ca2+ response of bone cells experiencing fluid flow. (1996) (191)
Treatment of recalcitrant non-union with a capacitively coupled electrical field. A preliminary report. (1985) (163)
Healing of nonunion of the medial malleolus by means of direct current: a case report. (1971) (151)
Osteonecrosis of the femoral head. Results of core decompression and grafting with and without electrical stimulation. (1989) (142)
Early histological and ultrastructural changes in medullary fracture callus. (1991) (135)
Stimulation of fracture healing by direct current in the rabbit fibula. (1971) (133)
A double-blind study of capacitively coupled electrical stimulation as an adjunct to lumbar spinal fusions. (1999) (132)
Treatment of nonunion with constant direct current. (1977) (132)
Use of Physical Forces in Bone Healing (2003) (132)
Tibial Nonunion Treated With Direct Current, Capacitive Coupling, or Bone Graft (1995) (127)
Bone reaction to varying amounts of direct current. (1970) (123)
Mitochondrial calcium and its role in calcification. Histochemical localization of calcium in electron micrographs of the epiphyseal growth plate with K-pyroantimonate. (1974) (121)
The response of non-traumatized bone to direct current. (1974) (120)
Direct-current stimulation of non-union and congenital pseudarthrosis. Exploration of its clinical application. (1975) (117)
Bone formation and repair (1994) (114)
Cellular responses to chemical and morphologic aspects of biomaterial surfaces. II. The biosynthetic and migratory response of bone cell populations. (1995) (112)
Similarities in the phenotypic expression of pericytes and bone cells. (1998) (112)
Identification of integrin receptors on cultured human bone cells (1994) (112)
The Biochemical Pathway Mediating the Proliferative Response of Bone Cells to a Mechanical Stimulus* (1996) (108)
Pathophysiology of delayed healing. (1998) (108)
Signal transduction in electrically stimulated articular chondrocytes involves translocation of extracellular calcium through voltage-gated channels. (2009) (107)
Cytoplasmic structures of epiphyseal plate chondrocytes. Quantitative evaluation using electron micrographs of rat costochondral junctions with special reference to the fate of hypertrophic cells. (1973) (106)
Anaerobic and aerobic metabolism in articular cartilage. (1977) (106)
Fracture healing in the rabbit fibula when subjected to various capacitively coupled electrical fields (1985) (106)
The growth plate. (1984) (103)
Up-regulation of bone morphogenetic proteins in cultured murine bone cells with use of specific electric fields. (2006) (103)
The treatment of non-unions with electricity. (1981) (95)
Histochemical localization of calcium in growth plate mitochondria and matrix vesicles. (1976) (93)
Cathodic oxygen consumption and electrically induced osteogenesis. (1975) (90)
The effect of electrical fields on gene and protein expression in human osteoarthritic cartilage explants. (2008) (87)
The inositol phosphate pathway as a mediator in the proliferative response of rat calvarial bone cells to cyclical biaxial mechanical strain (1992) (83)
In vitro epiphyseal-plate growth in various oxygen tensions. (1969) (82)
In vitro bone-cell response to a capacitively coupled electrical field. The role of field strength, pulse pattern, and duty cycle. (1992) (81)
Up-regulation of Chondrocyte Matrix Genes and Products by Electric Fields (2004) (81)
Treatment of avascular necrosis of the femoral head by a combination of bone grafting, decompression, and electrical stimulation. (1984) (80)
Structure and function of the growth plate. (1978) (80)
Early histologic and ultrastructural changes in microvessels of periosteal callus. (1997) (79)
Biochemical Pathway Mediating the Response of Bone Cells to Capacitive Coupling (1998) (76)
What is the role of the convective current density in the real-time calcium response of cultured bone cells to fluid flow? (1996) (75)
Joint resurfacing in the rabbit using an autologous osteochondral graft. (1977) (74)
Mitochondrial Calcium and Its Role in Calcification (1974) (71)
Mechanical strain-induced proliferation of osteoblastic cells parallels increased TGF-beta 1 mRNA. (1996) (71)
Identification of integrin cell‐substratum adhesion receptors on cultured rat bone cells (1992) (69)
The biology of fracture repair. (1984) (66)
Early results in the treatment of avascular necrosis of the femoral head with electrical stimulation. (1984) (64)
The effect of oxygen tension on proteoglycan synthesis and aggregation in mammalian growth plate chondrocytes (1991) (63)
Articular cartilage preservation and storage (1979) (63)
In vitro growth of bovine articular cartilage chondrocytes in various capacitively coupled electrical fields (1984) (61)
Treatment of chronic osteomyelitis complicating nonunion and segmental defects of the tibia with open cancellous bone graft, posterolateral bone graft, and soft-tissue transfer. (1990) (58)
Capacitive coupling as an adjunctive treatment for avascular necrosis. (1990) (58)
Fracture healing in the presence of chronic hypoxia. (1976) (57)
ELECTRICAL STIMULATION AND OXYGEN TENSION * (1974) (56)
Response of cultured bone cells to a capacitively coupled electric field: Inhibition of cAMP response to parathyroid hormone (1988) (54)
Serum modulates the intracellular calcium response of primary cultured bone cells to shear flow. (2000) (52)
Electrical properties of bone and cartilage : experimental effects and clinical applications (1979) (52)
Histochemical localization of calcium in the fracture callus with potassium pyroantimonate. Possible role of chondrocyte mitochondrial calcium in callus calcification. (1986) (50)
Treatment of denervation/disuse osteoporosis in the rat with a capacitively coupled electrical signal: Effects on bone formation and bone resorption (1988) (50)
Adjunctive hyperbaric oxygen therapy in the treatment of chronic refractory osteomyelitis. (1986) (50)
Up-regulation of matrix in bovine articular cartilage explants by electric fields. (2006) (50)
Prevention and treatment of sciatic denervation disuse osteoporosis in the rat tibia with capacitively coupled electrical stimulation. (1985) (49)
Capacitively coupled electrical stimulation of bovine growth plate chondrocytes grown in pellet form (1988) (48)
Psychosocial, functional, and quality of life assessment of patients with posttraumatic fracture nonunion, chronic refractory osteomyelitis, and lower extremity amputation. (1991) (47)
Articular cartilage preservation and storage. II. Mechanical indentation testing of viable, stored articular cartilage. (1979) (47)
Zonal analysis of cytoplasmic components of articular cartilage chondrocytes. (1984) (46)
In vitro epiphyseal-plate growth in various constant electrical fields. (1976) (46)
Electrically induced osteogenesis: relationship between charge, current density, and the amount of bone formed: introduction of a new cathode concept. (1981) (46)
The role of mitochondria in growth plate calcification as demonstrated in a rachitic model. (1978) (46)
Microvascular pericytes express aggrecan message which is regulated by BMP-2. (2000) (46)
Antibiotic Penetration into Rabbit Nucleus Pulposus (1987) (46)
Prognostic factors in nonunion of the tibia: an evaluation of 185 cases treated with constant direct current. (1984) (45)
In vivo growth plate stimulation in various capacitively coupled electrical fields (1984) (45)
Up‐regulation of expression of selected genes in human bone cells with specific capacitively coupled electric fields (2014) (45)
Chondrolysis of the hip. (1974) (44)
Electron microscopic pyroantimonate studies of matrix vesicles and mitochondria in the rachitic growth plate (1978) (42)
Proliferation and macromolecular synthesis by rat calvarial bone cells grown in various oxygen tensions (1991) (42)
MALIGNANT HEMANGIOENDOTHELIOMA OF BONE: REPORT OF TWO CASES AND REVIEW OF THE LITERATURE. (1965) (42)
In vitro rabbit articular cartilage organ model. II. 35S incorporation in various oxygen tensions. (1974) (41)
Ultrastructure of electrically induced osteogenesis in the rabbit medullary canal (1986) (40)
Enhanced survival of rat neonatal cerebral cortical neurons at subatmospheric oxygen tensions in vitro (1986) (40)
Electrical osteogenesis by low direct current (1983) (39)
Treatment of castration-induced osteoporosis by a capacitively coupled electrical signal in rat vertebrae. (1989) (39)
Treatment of nonunion of the tibia with a capacitively coupled electrical field. (1984) (39)
Microvessel endothelial cells and pericytes increase proliferation and repress osteoblast phenotypic markers in rat calvarial bone cell cultures (1995) (39)
Iron-induced arthritis in immature rabbits. (1970) (38)
Treatment of nonunion of the tibia with constant direct current (1980 Fitts Lecture, A.A.S.T.). (1981) (37)
Nonunion of the humerus. Clinical, roentgenographic, scintigraphic, and response characteristics to treatment with constant direct current stimulation of osteogenesis. (1986) (37)
The effect of ascorbic acid on the metabolism of rat calvarial bone cells in vitro (1989) (37)
Proliferative and synthetic response of bovine growth plate chondrocytes to various capacitively coupled electrical fields (1989) (37)
Low-power electromagnetic stimulation of osteotomized rabbit fibulae. A randomized, blinded study. (1994) (37)
Characterization of growth plate mitochondria (1984) (36)
Treatment of sciatic denervation disuse osteoporosis in the rat tibia with capacitively coupled electrical stimulation. Dose response and duty cycle. (1985) (36)
Comparison of asymmetrical and symmetrical pulse waveforms in electromagnetic stimulation (1992) (35)
The cellular origin of bioelectric potentials in bone (2005) (35)
Cytosolic ionized calcium concentration in isolated chondrocytes from each zone of the growth plate (1989) (34)
Biosynthesis of a disulphide-bonded short-chain collagen by calf growth-plate cartilage. (1984) (33)
ELECTRICAL FRACTURE HEALING * (1974) (33)
Electromagnetics in Medicine and Biology (1991) (32)
Indium‐111 leukocyte scintigraphic detection of subclinical osteomyelitis complicating delayed and nonunion long bone fractures: A prospective study (1987) (32)
Articular cartilage preservation and storage. I. Application of tissue culture techniques to the storage of viable articular cartilage. (1979) (32)
Electrochemical aspects of d.c. stimulation of osteogenesis (1984) (31)
Role of bone scintigraphy in the evaluation and treatment of nonunited fractures: concise communication. (1980) (29)
The use and possible misuse of tetracycline as a vital stain. (1979) (28)
Biosynthesis of a low molecular weight collagen by rabbit growth plate cartilage organ cultures. (1983) (28)
Changes in bioelectric potentials on bone associated with direct current stimulation of osteogenesis (1988) (28)
PRIMARY ARTICULAR-CARTILAGE CALCIFICATION WITH ARTHRITIS (PSEUDOGOUT SYNDROME). (1965) (27)
Growth Plate Matrix Vesicle Biogenesis: The Role of Intracellular Calcium (1994) (26)
In vitro rabbit articular cartilage organ model. I. Morphology and glycosaminoglycan metabolism. (1974) (25)
The Required Research Rotation in Residency: The University of Pennsylvania Experience, 1978-1993 (2006) (25)
Detection of synovial pseudarthrosis by 99mTc scintigraphy: application to treatment of traumatic nonunion with constant direct current. (1981) (24)
Mechanism of action of parathyroid hormone‐induced proteoglycan synthesis in the growth plate chondrocyte (1990) (24)
Increased cAMP production after short‐term capacitively coupled stimulation in bovine growth plate chondrocytes (1988) (24)
Arthropathy, skin and bone lesions in pancreatic disease. (1975) (24)
Electro-Osteograms of Long Bones of Immature Rabbits (1971) (23)
The effects of demineralized bone matrix and direct current on an “in vivo” culture of bone marrow cells (1989) (23)
Calcium flux and endogenous calcium content in isolated mammalian growth-plate chondrocytes, hyaline-cartilage chondrocytes, and hepatocytes. (1985) (23)
Analysis of physeal growth in dogs, using biplanar radiography. (1994) (23)
Field distribution in vertebral bodies of the rat during electrical stimulation: a parameter study (1989) (21)
Atraumatic aspiration of whole blood for intraoperative autotransfusion. (1972) (21)
Electrical stimulation in the treatment of osteonecrosis of the femoral head--a 1-year follow-up. (1985) (19)
Diffusion in the various zones of the normal and the rachitic growth plate. (1980) (19)
Direct current stimulation of bone production in the horse: preliminary study with a "gap healing" model. (1985) (19)
The semi-invasive method of treating nonunion with direct current. (1984) (18)
Failure of the rabbit tibial growth plate to respond to the long‐term application of a capacitively‐coupled electrical field (1986) (17)
Sequential changes in the mechanical properties of viable articular cartilage stored in vitro (1984) (17)
Pulsing electromagnetic field stimulation of the in vitro growth plate (1988) (16)
Synovial pseudarthrosis: a clinical, roentgenographic-scintigraphic, and pathologic study. (1987) (16)
Experimental hydroxyapatite synovial and articular cartilage calcification: light and electron microscopic studies. (1982) (16)
Temporal course of bone formation in response to constant direct current stimulation (1985) (15)
Bioelectricity and fracture healing. (1981) (15)
Oxygen tension of nonunion of fractured femurs in the rabbit. (1972) (15)
Theoretical determination of the current density distributions in human vertebral bodies during electrical stimulation (1990) (14)
Morphology and biochemistry of the growth plate. (1987) (14)
The electrical treatment of scaphoid nonunion. (1981) (14)
An in vitro study of electrical osteogenesis using direct and pulsating currents. (1979) (13)
Use of constant direct current in the treatment of nonunion. (1982) (13)
The increased level of PDGF‐A contributes to the increased proliferation induced by mechanical stimulation in osteoblastic cells (1997) (12)
Alkaline phosphatase production by periosteal cells at various oxygen tensions in vitro. (1990) (11)
Radiologic evaluation of the treatment of nonunion of fractures by electrical stimulation. (1978) (11)
Treatment of nonunion of the scaphoid by direct current. (1984) (11)
The experimental induction of localised skeletal tuberculous lesions and their accessibility to streptomycin. (1974) (11)
Quantitative zonal analysis of cytoplasmic structures of growth-plate chondrocytes in vivo and in vitro. (1982) (11)
Multiple pathologic fractures of the appendicular skeleton in a patient with Cushing's disease. (1987) (10)
Fracture Healing in the Presence of Anemia (1977) (10)
Neutropenia complicating parenteral antibiotic treatment of infected nonunion of the tibia. (1989) (10)
Medullary osteogenesis with platinum cathodes (1985) (9)
Absence of the glycerol phosphate shuttle in the various zones of the growth plate. (1983) (9)
Cytosolic calcium concentration in bovine growth plate chondrocytes (1987) (9)
Subcellular regulation of the ionized calcium pool in isolated growth-plate chondrocytes. (1989) (8)
Longitudinal bone growth: the growth plate and its dysfunctions. (1987) (7)
Treatment of chronic refractory osteomyelitis with adjunctive hyperbaric oxygen. (1988) (7)
Technetium and gallium scintigraphic evaluation of patients with long bone fracture nonunion. (1984) (7)
Oxygen tension of the epiphyseal plate distal to an arteriovenous fistula. (1971) (6)
Short-term effect of guided bone regeneration and electrical stimulation on bone growth in a surgically modelled resorbed dog mandibular ridge. (1992) (6)
Results of Treatment of 111 Patients With Nonunion of Femoral Shaft Fractures (1999) (6)
The origin of resting bioelectric potentials in the rabbit tibia. (1971) (5)
Cytoplasmic Structures of Epiphyseal Plate Chondrocytes QUANTITATIVE EVALUATION USING ELECTRON MICROGRAPHS OF RAT COSTOCHONDRALJUNCTIONS WITH SPECIAL REFERENCE (2006) (5)
Field distributions in vertebral bodies of the rat during electrical stimulation: a parametric study. (1989) (5)
A Spectrophotometric Analysis of Human Osteoarthritic Cartilage Explants Subjected to Specific Capacitively Coupled Electric Fields (2013) (5)
Articular cartilage biopsy. (1967) (5)
PANEL DISCUSSION: TO WHAT EXTENT CAN ELECTRICAL STIMULATION BE USED IN THE TREATMENT OF HUMAN DISORDERS? (1974) (4)
Clinical and roentgenographic evaluation of nonunion of the forearm in relation to treatment with D.C. electrical stimulation. (1983) (4)
Breakout session. 4: Biophysical enhancement. (1998) (4)
An oxygen microelectrode suitable for cartilage and cancellous bone. (1971) (4)
Amelioration of oxygen‐induced osteoporosis in the in vitro fetal rat tibia with a capacitively coupled electrical field (1985) (4)
Direct current stimulation of bone production in the pony: observations with a diaphyseal osteotomy model. (1985) (3)
Recent advances in electrical stimulation. (1993) (3)
Electrical stimulation of onlay bone grafts. (1988) (3)
Direct extracellular electrical stimulation influences density dependent aggregation of fetal rat cerebrocortical neurons in vitro (1988) (3)
Comparison of the effects of excess vitamin A and high oxygen tension onin vitro epiphyseal plate growth (1970) (2)
Editorial: Orthopaedic Surgeons and Basic Research (1992) (2)
Electrical treatment for non-union (1982) (2)
An ultrastructural study using strontium to trace the pathway of calcium in the growth plate (1985) (1)
Resection of Clavicle Nonunions (1992) (1)
Inhibition of proteoglycan degradation in rabbit articular cartilage organ cultures by superoxide dismutase and proteolytic enzyme inhibitors (1981) (1)
A randomized, blinded study Low-power electromagnetic stimulation of osteotomized rabbit fibulae. (2006) (0)
In Vitro Calvaria Bone Cell ( Osteoblast-like cell ) (2009) (0)
EVALUATION AND MANAGEMENT OF NONUNIONS OF THE FOREARM (1982) (0)
A Tribute to the Guest Editors: Volumes 301 to 400 (2002) (0)
Biosynthesis of a Disulfide‐bonded Type X Collagen in Bovine Growth Plate Cartilage a (1985) (0)
Effects of pO2, β-glycerophosphate, and Dexamethasone on the Proliferation of In Vitro Calvaria Bone Cells (1991) (0)
Osteogenic response to low electric current and silver electrodes. (1985) (0)
Articular cartilage preservation and storage. III. Quantitative zonal analysis of cytoplasmic components of stored versus in vivo articular cartilage chondrocytes. (1990) (0)
Comparison of Bone Graft Surgery to Electricity in the Treatment of Tibial Nonunion. Direct Current and Capacitive Coupling (1989) (0)
The site of action of oxygen toxicity during in vitro epiphyseal plate growth. (1969) (0)
International Symposium on bone vascularization (1982) (0)
Fibrous dysplasia associated with sickle-cell disease. Report of a case with a discussion of the multiple factors affecting both conditions. (1967) (0)
ETIOLOGY AND RESPONSE TO TREATMENT OF SIXTY-FOUR FEMORAL NONUNIONS (1982) (0)
Portable electrotherapy system. (1987) (0)
Orthopedic surgery. (1976) (0)
PROGNOSTIC FACTORS IN NONUSION OF THE TIBIA IN AN EVALUATION OF 185 CASES (1983) (0)
ABSENCE OF THE GLYCEROL PHOSPHATE SHUTTLE IN THE VARIOUS ZONES OF THE GROWTH PLATE (1983) (0)
disulphide-bonded short-chain collagen by calf growth-plate cartilage (2005) (0)

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