Caleb Finch
#15,055
Most Influential Person Now
American scientist
Caleb Finch's AcademicInfluence.com Rankings
Caleb Finchsocial-work Degrees
Social Work
#3
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#6
Historical Rank
#3
USA Rank
Gerontology
#1
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#1
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#1
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Caleb Finchbiology Degrees
Biology
#940
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#1639
Historical Rank
#504
USA Rank
Zoology
#52
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#172
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#20
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Neuroscience
#274
World Rank
#289
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#105
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Social Work Biology
Caleb Finch's Degrees
- PhD Zoology University of California, Berkeley
- Masters Zoology University of California, Berkeley
- Bachelors Zoology University of California, Berkeley
Why Is Caleb Finch Influential?
(Suggest an Edit or Addition)According to Wikipedia, Caleb Ellicott Finch is an American academic who is a professor at the USC Davis School of Gerontology. Finch's research focuses on aging in humans, with a specialization in cell biology and Alzheimer's disease.
Caleb Finch's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Inflammation and Alzheimer’s disease (2000) (4327)
- Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. (1998) (3525)
- Longevity, senescence, and the genome (1990) (1376)
- Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase (2008) (1268)
- Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss (2003) (1081)
- Targeting small Aβ oligomers: the solution to an Alzheimer's disease conundrum? (2001) (1024)
- Synaptic Targeting by Alzheimer's-Related Amyloid β Oligomers (2004) (824)
- Inflammatory Exposure and Historical Changes in Human Life-Spans (2004) (716)
- Cytokines and Cognition—The Case for A Head‐to‐Toe Inflammatory Paradigm (2002) (605)
- Evolutionary Medicine: From Dwarf Model Systems to Healthy Centenarians? (2003) (598)
- Progesterone receptors: Form and function in brain (2008) (525)
- Evidence for Apoptotic Cell Death in Alzheimer's Disease (1995) (504)
- Synaptic targeting by Alzheimer's-related amyloid beta oligomers. (2004) (489)
- A longitudinal study of estrous cyclicity in aging C57BL/6J mice: I. Cycle frequency, length and vaginal cytology. (1982) (463)
- Self-assembly of Aβ1-42 into globular neurotoxins (2003) (456)
- Infection, inflammation, height, and longevity. (2006) (432)
- Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning. (1991) (388)
- GFAP mRNA increases with age in rat and human brain (1993) (363)
- Vascular dysfunction—The disregarded partner of Alzheimer's disease (2019) (361)
- Between Zeus and the Salmon: The Biodemography of Longevity (1998) (358)
- Catecholamine metabolism in the brains of ageing male mice. (1973) (354)
- The genetics of aging. (1997) (352)
- Hormones and the Physiological Architecture of Life History Evolution (1995) (349)
- Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat (1990) (343)
- Clusterin (apoJ) Alters the Aggregation of Amyloid β-Peptide (Aβ1-42) and Forms Slowly Sedimenting Aβ Complexes That Cause Oxidative Stress (1995) (337)
- Vaccination with soluble Aβ oligomers generates toxicity‐neutralizing antibodies (2001) (335)
- Atherosclerosis across 4000 years of human history: the Horus study of four ancient populations (2013) (325)
- Caloric restriction attenuates Aβ-deposition in Alzheimer transgenic models (2005) (320)
- Joint Genome-Wide Profiling of miRNA and mRNA Expression in Alzheimer's Disease Cortex Reveals Altered miRNA Regulation (2010) (319)
- Evolution of the human lifespan and diseases of aging: Roles of infection, inflammation, and nutrition (2009) (315)
- Chance, development, and aging (2000) (314)
- Ovarian and steroidal influences on neuroendocrine aging processes in female rodents. (1984) (305)
- Genetics of aging. (2003) (282)
- Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models (2017) (276)
- Peroxynitrite Mediates Neurotoxicity of Amyloid β-Peptide1–42- and Lipopolysaccharide-Activated Microglia (2002) (273)
- Slow mortality rate accelerations during aging in some animals approximate that of humans. (1990) (264)
- The rise and fall of excess male infant mortality (2008) (257)
- Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease. (1990) (250)
- Age-Related Activation of Microglia and Astrocytes: In Vitro Studies Show Persistent Phenotypes of Aging, Increased Proliferation, and Resistance to Down-Regulation (1998) (245)
- The Regulation of Physiological Changes During Mammalian Aging (1976) (244)
- Increased Synaptic Sprouting in Response to Estrogen via an Apolipoprotein E-Dependent Mechanism: Implications for Alzheimer’s Disease (1998) (244)
- Astrocytes and Microglia Respond to Estrogen with Increased apoE mRNAin Vivoandin Vitro (1997) (240)
- Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease. (1995) (225)
- Age‐Correlated Loss of Dopaminergic Binding Sites in Human Basal Ganglia (1982) (225)
- Coronary atherosclerosis in indigenous South American Tsimane: a cross-sectional cohort study (2017) (224)
- Extensive postmortem stability of RNA from rat and human brain (1986) (219)
- Glial Fibrillary Acidic Protein: Regulation by Hormones, Cytokines, and Growth Factors (1994) (215)
- Altered profiles of estradiol and progesterone associated with prolonged estrous cycles and persistent vaginal cornification in aging C57BL/6J mice. (1981) (208)
- Self-assembly of Abeta(1-42) into globular neurotoxins. (2003) (208)
- Reduced dopaminergic binding during aging in the rodent striatum (1980) (203)
- The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction (1999) (201)
- TGF‐β1 is an organizer of responses to neurodgeneration (1993) (187)
- Imminent oocyte exhaustion and reduced follicular recruitment mark the transition to acyclicity in aging C57BL/6J mice. (1983) (187)
- Complement mRNA in the mammalian brain: Responses to Alzheimer's disease and experimental brain lesioning (1992) (184)
- TGF-β1 mRNA Increases in Macrophage/Microglial Cells of the Hippocampus in Response to Deafferentation and Kainic Acid-Induced Neurodegeneration (1993) (184)
- Glutamatergic Neurons in Rodent Models Respond to Nanoscale Particulate Urban Air Pollutants in Vivo and in Vitro (2011) (182)
- Age-related changes in glial fibrillary acidic protein mRNA in the mouse brain (1991) (179)
- Sulfated glycoprotein 2: new relationships of this multifunctional protein to neurodegeneration (1992) (178)
- Longitudinal studies of estrous cyclicity in aging C57BL/6J mice: II. Cessation of cyclicity and the duration of persistent vaginal cornification. (1984) (175)
- Functional annotation and network reconstruction through cross-platform integration of microarray data (2005) (173)
- Systemic inflammation, infection, ApoE alleles, and Alzheimer disease: a position paper. (2007) (173)
- Dopamine and Serotonin Systems in Human and Rodent Brain: Effects of Age and Neurodegenerative Disease (1987) (173)
- The evolution of Alzheimer disease, the reproductive schedule, and apoE isoforms☆ (1999) (170)
- Meat‐Adaptive Genes and the Evolution of Slower Aging in Humans (2004) (170)
- Evidence for an interaction between apolipoprotein E genotype, gender, and Alzheimer disease. (1999) (168)
- Lingering prenatal effects of the 1918 influenza pandemic on cardiovascular disease. (2010) (168)
- The neurobiology of Alzheimer's disease. (1989) (166)
- Neurons, glia, and plasticity in normal brain aging (2003) (163)
- Estrogen Enhances Uptake of Amyloid β‐Protein by Microglia Derived from the Human Cortex (2000) (158)
- The Biology of Human Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans (2007) (156)
- Messenger RNA for glial fibrillary acidic protein is decreased in rat brain following acute and chronic corticosterone treatment. (1990) (148)
- Aging, Metabolism, and Alzheimer Disease: Review and Hypotheses (1997) (146)
- Complement C1qB and C4 mRNAs responses to lesioning in rat brain (1992) (145)
- Clusterin (SGP‐2): A multifunctional glycoprotein with regional expression in astrocytes and neurons of the adult rat brain (1994) (141)
- Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments. (2012) (138)
- What accounts for the wide variation in life span of genetically identical organisms reared in a constant environment? (2005) (137)
- Serotonin-2 binding sites in human frontal cortex and hippocampus. Selective loss of S-2A sites with age (1984) (135)
- Aging and glial responses to lipopolysaccharide in vitro: greater induction of IL-1 and IL-6, but smaller induction of neurotoxicity (2003) (133)
- Maximum life span predictions from the Gompertz mortality model. (1996) (133)
- Neuron atrophy during aging: programmed or sporadic? (1993) (130)
- Ageing and the Regulation of Cell Activities during Exposure to Cold (1969) (128)
- Bidirectional transcription regulation of glial fibrillary acidic protein by estradiol in vivo and in vitro. (1998) (127)
- Aging and inflammation in two epidemiological worlds. (2008) (126)
- Update on Slow Aging and Negligible Senescence – A Mini-Review (2009) (124)
- Next-generation sequencing in aging research: Emerging applications, problems, pitfalls and possible solutions (2010) (124)
- Purification and characterization of brain clusterin. (1994) (124)
- Increased transcription of the astrocyte gene GFAP during middle-age is attenuated by food restriction: implications for the role of oxidative stress. (1997) (123)
- Increases of glial fibrillary acidic protein in the aging female mouse brain (1995) (123)
- Ageing and dopamine uptake by subcellular fractions of the C57BL/6J male mouse brain (1975) (121)
- The glucocorticoid paradox of caloric restriction in slowing brain aging (2002) (118)
- The Evolution of the Human Life Course (1997) (118)
- Restoration of ovulatory cycles by young ovarian grafts in aging mice: potentiation by long-term ovariectomy decreases with age. (1983) (116)
- Nanoscale Particulate Matter from Urban Traffic Rapidly Induces Oxidative Stress and Inflammation in Olfactory Epithelium with Concomitant Effects on Brain (2016) (114)
- Twentieth century surge of excess adult male mortality (2015) (114)
- Castration enhances expression of glial fibrillary acidic protein and sulfated glycoprotein-2 in the intact and lesion-altered hippocampus of the adult male rat. (1990) (113)
- Complement Activation in Very Early Alzheimer Disease (2005) (111)
- Gonadal steroids regulate the expression of glial fibrillary acidic protein in the adult male rat hippocampus (1993) (110)
- Role of the gonads in the histologic aging of the hypothalamic arcuate nucleus. (1981) (108)
- Transforming growth factor-β1 induces neuronal and astrocyte genes: Tubulin α1, glial fibrillary acidic protein and clusterin (1994) (107)
- Selective expression of clusterin (SGP-2) and complement C1qB and C4 during responses to neurotoxinsin vivo andin vitro (1994) (106)
- The Demographic and Biomedical Case for Late-Life Interventions in Aging (2010) (106)
- Inflammation and Infection Do Not Promote Arterial Aging and Cardiovascular Disease Risk Factors among Lean Horticulturalists (2009) (105)
- Transforming growth factor β1 and fibronectin messenger RNA in rat brain: Responses to injury and cell-type localization (1993) (102)
- Differential contributions of ovarian and extraovarian factors to age-related reductions in plasma estradiol and progesterone during the estrous cycle of C57BL/6J mice. (1992) (102)
- Trajectories of Mortality at Advanced Ages (1997) (101)
- Prenatal Exposure to Urban Air Nanoparticles in Mice Causes Altered Neuronal Differentiation and Depression-Like Responses (2013) (100)
- Selective reduction of mRNA for the β-amyloid precursor protein that lacks a Kunitz-type protease inhibitor motif in cortex from Alzheimer brains (1988) (99)
- Reproductive aging in C57BL/6J mice: plasma progesterone, viable embryos and resorption frequency throughout pregnancy. (1979) (99)
- Anti-inflammatory mechanisms of dietary restriction in slowing aging processes. (2007) (98)
- Enzyme activities, gene function and ageing in mammals. (Review). (1972) (97)
- Estradiol (E2) enhances neurite outgrowth by repressing glial fibrillary acidic protein expression and reorganizing laminin. (2002) (97)
- The menopause and aging, a comparative perspective (2014) (96)
- Catecholamine levels and turnover during aging in brain regions of male C57BL/6J mice (1981) (95)
- Variations in senescence and longevity include the possibility of negligible senescence. (1998) (95)
- Cloning of hippocampal poly(A) RNA sequences that increase after entorhinal cortex lesion in adult rat. (1991) (94)
- BDNF and trkB mRNA expression in the hippocampal formation of aging rats (1993) (94)
- Ambient ultrafine particles alter lipid metabolism and HDL anti-oxidant capacity in LDLR-null mice[S] (2013) (92)
- Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo (2017) (91)
- Glial Fibrillary Acidic Protein Transcription Responses to Transforming Growth Factor‐β1 and Interleukin‐1β Are Mediated by a Nuclear Factor‐1‐Like Site in the Near‐Upstream Promoter (1999) (90)
- Genotypic influences on striatal dopaminergic regulation in mice (1981) (90)
- History and prospects: symposium on organisms with slow aging (2001) (89)
- Blood lipids, infection, and inflammatory markers in the Tsimane of Bolivia (2010) (87)
- Ageing: The old worm turns more slowly (2002) (87)
- Between Zeus and the Salmon (1997) (85)
- Increases in transforming growth factor‐β mRNA in hippocampus during response to entorhinal cortex lesions in intact and adrenalectomized rats (1991) (85)
- Neuroendocrine and pharmacological manipulations to assess how caloric restriction increases life span. (2001) (84)
- LHRH neurons in the female C57BL/6J mouse brain during reproductive aging: No loss up to middle age (1986) (83)
- Reproductive senescence in female C57BL/6J mice: ovarian impairments and neuroendocrine impairments that are partially reversible and delayable by ovariectomy. (1984) (83)
- NSAIDS inhibit the IL-1β-induced IL-6 release from human post-mortem astrocytes: the involvement of prostaglandin E2 (1997) (83)
- Traffic-related air pollution impact on mouse brain accelerates myelin and neuritic aging changes with specificity for CA1 neurons (2017) (82)
- The need for multiple time points in aging studies (1990) (82)
- RNA and protein metabolism in the aging brain. (1990) (82)
- Divergent changes in D-1 and D-2 dopamine binding sites in human brain during aging (1987) (81)
- Dopaminergic Changes in the Basal Ganglia A Generalized Phenomenon of Aging in Mammals a (1988) (80)
- Hereditary Deficiencies in Complement C5 Are Associated with Intensified Neurodegenerative Responses That Implicate New Roles for the C-System in Neuronal and Astrocytic Functions (1996) (80)
- Plasma testosterone levels in C57BL/6J male mice: effects of age and disease. (1975) (79)
- Aging and the regulation of striatal dopaminergic mechanisms in mice. (1981) (77)
- Glycoprotein 330/Megalin (LRP-2) Has Low Prevalence as mRNA and Protein in Brain Microvessels and Choroid Plexus (1999) (76)
- Effect of chronic adrenalectomy on neuron loss and distribution of sulfated glycoprotein-2 in the dentate gyrus of prepubertal rats (1991) (76)
- Clusterin expression by astrocytes is influenced by transforming growth factor β1 and heterotypic cell interactions (1995) (76)
- In Search of Limits (1997) (76)
- Why Men Die Younger : Causes of Mortality Differences by Sex (74)
- Sequence complexity of polyadenylated RNA obtained from rat brain regions and cultured rat cells of neural origin. (1978) (73)
- Parkinson’s Disease—II (1978) (72)
- The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity (2015) (71)
- The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice (2016) (71)
- Slow changes of tyrosine hydroxylase gene expression in dopaminergic brain neurons after neurotoxin lesioning: a model for neuron aging. (1992) (70)
- TGF-beta 1 is an organizer of responses to neurodegeneration. (1993) (68)
- Response of striatal astrocytes to neuronal deafferentation: An immunocytochemical and ultrastructural study (1994) (68)
- Macrosialin increases during normal brain aging are attenuated by caloric restriction (2005) (67)
- A critical review of assays for hazardous components of air pollution. (2018) (67)
- Developmental origins of aging in brain and blood vessels: an overview (2005) (67)
- Apolipoprotein E4 is associated with improved cognitive function in Amazonian forager‐horticulturalists with a high parasite burden (2017) (65)
- The Evolution of Senescence (1997) (65)
- Transcriptional regulation of glial fibrillary acidic protein by corticosterone in rat astrocytes in vitro is influenced by the duration of time in culture and by astrocyte-neuron interactions. (1995) (65)
- Absence of c-fos induction in neonatal rat brain after seizures (1992) (65)
- Elevated Density of [3H]Imipramine Binding in Aged Human Brain (1985) (64)
- Aging and the regulation of luteinizing hormone in C57BL/6J mice: impaired elevations after ovariectomy and spontaneous elevations at advanced ages. (1983) (64)
- Prenatal and early life exposure to air pollution induced hippocampal vascular leakage and impaired neurogenesis in association with behavioral deficits (2018) (63)
- Chronic lesions differentially decrease tyrosine hydroxylase messenger RNA in dopaminergic neurons of the substantia nigra. (1989) (63)
- Altered Gene Expression in Alzheimer's Disease Brain Tissue (1989) (63)
- Reversible age impairments in neurite outgrowth by manipulations of astrocytic GFAP (2005) (62)
- Age effects on luteinizing hormone, progesterone and prolactin in proestrous and acyclic C57BL/6j mice. (1982) (62)
- The neurobiology of middle-age has arrived (2009) (61)
- Primate aging in the mammalian scheme: the puzzle of extreme variation in brain aging (2012) (61)
- Glucocorticoid endangerment of hippocampal neurons does not involve deoxyribonucleic acid cleavage. (1989) (60)
- C1qB and clusterin mRNA increase in association with neurodegeneration in sporadic amyotrophic lateral sclerosis (1999) (60)
- APOE Alleles and Diet in Brain Aging and Alzheimer’s Disease (2020) (58)
- 17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain. (2012) (58)
- The Oxygen Paradox, the French Paradox, and age-related diseases (2017) (57)
- Urban air pollutants reduce synaptic function of CA1 neurons via an NMDA/NȮ pathway in vitro (2013) (57)
- Age-dependent increases of DNA adducts (I-compounds) in human and rat brain DNA. (1993) (57)
- Sulfated glycoprotein-2 (SGP-2) mRNA is expressed in rat striatal astrocytes following ibotenic acid lesions (1991) (56)
- Corticosterone differentially regulates the bilateral response of astrocyte mRNAs in the hippocampus to entorhinal cortex lesions in male rats. (1991) (56)
- Commentary: is Alzheimer's disease uniquely human? (2015) (56)
- Continuous versus Cyclic Progesterone Exposure Differentially Regulates Hippocampal Gene Expression and Functional Profiles (2012) (56)
- Gene Aging Nexus: a web database and data mining platform for microarray data on aging (2006) (55)
- Urban traffic-derived nanoparticulate matter reduces neurite outgrowth via TNFα in vitro (2016) (55)
- Sulfated glycoprotein-2 is increased in rat hippocampus following entorhinal cortex lesioning (1991) (55)
- Estradiol-induced adult anovulatory syndrome in female C57BL/6J mice: age-like neuroendocrine, but not ovarian, impairments. (1984) (54)
- Effective oral administration of 17 beta-estradiol to female C57BL/6J mice through the drinking water. (1986) (54)
- Age-related changes in brain catecholamines: a synopsis of findings in C57BL/6J mice and other rodent models. (1978) (54)
- Differential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17β-estradiol and progesterone in hippocampal subregions that support synaptic remodeling and neurogenesis. (2012) (53)
- Transcription supports age-related increases of GFAP gene expression in the male rat brain (1996) (53)
- Evolution of the human lifespan, past, present, and future: phases in the evolution of human life expectancy in relation to the inflammatory load. (2012) (53)
- Learning Induces a CDC2-Related Protein Kinase, KKIAMRE (1999) (52)
- Endocrine patterns during aging in the common tern (Sterna hirundo). (1999) (52)
- Tyrosine Hydroxylase mRNA Concentration in Midbrain Dopaminergic Neurons Is Differentially Regulated by Reserpine (1990) (52)
- Selective alterations of RNA in rat hippocampus after entorhinal cortex lesioning. (1990) (52)
- Brain Poly(A)RNA During Aging: Stability of Yield and Sequence Complexity in Two Rat Strains (1980) (51)
- Food restriction delays the age-related increase in GFAP mRNA in rat hypothalamus (1995) (50)
- Cardiovascular disease and type 2 diabetes in evolutionary perspective: A critical role for helminths? (2016) (50)
- APP-695 transcript prevalence is selectively reduced during Alzheimer's disease in cortex and hippocampus but not in cerebellum (1989) (50)
- Life-Long Dietary Restriction Attenuates Age-Related Increases in Hippocampal Glial Fibrillary Acidic Protein mRNA (1997) (50)
- Traffic-related air pollutants (TRAP-PM) promote neuronal amyloidogenesis through oxidative damage to lipid rafts. (2019) (50)
- Glial fibrillary acidic protein mRNA increases at proestrus in the arcuate nucleus of mice (1995) (49)
- Hormone production by the pituitary and testes of male C57BL/6J mice during aging. (1977) (49)
- Inflammation in Alzheimer’s Disease (2001) (49)
- Toxicity of urban air pollution particulate matter in developing and adult mouse brain: Comparison of total and filter-eluted nanoparticles. (2020) (49)
- Age-correlated and ovary-dependent changes in relationships between plasma estradiol and luteinizing hormone, prolactin, and growth hormone in female C57BL/6J mice. (1985) (49)
- Early cohort mortality predicts the rate of aging in the cohort: a historical analysis (2012) (48)
- Effect of APOE ε4 allele on survival and fertility in an adverse environment (2017) (48)
- Transcriptional control of glial fibrillary acidic protein and glutamine synthetase in vivo shows opposite responses to corticosterone in the hippocampus. (1994) (48)
- :Evolution of the Human Diet: The Known, the Unknown, and the Unknowable (2008) (47)
- Apolipoprotein J (clusterin) activates rodent microglia in vivo and in vitro (2005) (47)
- Studies on ovarian-hypothalamic-pituitary interactions during reproductive aging in C57BL/6J mice (1980) (47)
- Contamination of serotonin-2 binding sites by an alpha-1 adrenergic component in assays with (3H)spiperone. (1984) (47)
- Glial gene expression during aging in rat striatum and in long‐term responses to 6‐OHDA lesions (1999) (47)
- Prolongation and cessation of estrous cycles in aging C57BL/6J mice are differentially regulated events. (1986) (46)
- THE EFFECT OF AGEING ON RNA/DNA RATIOS IN BRAIN REGIONS OF THE C57BL/6J MALE MOUSE (1973) (46)
- The Alzheimer's Disease Exposome (2019) (46)
- Changes in gene expression in hippocampus in response to glucocorticoids and stress (1990) (45)
- Effects of Age on Gene Expression during Estrogen-Induced Synaptic Sprouting in the Female Rat (2000) (45)
- Kainic Acid and Decorticating Lesions Stimulate the Synthesis of C1q Protein in Adult Rat Brain (1997) (45)
- Can Estrogens Prevent Neurodegeneration? (1997) (44)
- The relationships of aging changes in the basal ganglia to manifestations of Huntington's chorea (1980) (44)
- Methylation of the glial fibrillary acidic protein gene shows novel biphasic changes during brain development (1996) (43)
- APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice (2019) (43)
- Reversible Inactivation of Superoxide‐Sensitive Aconitase in Aβ1‐42‐Treated Neuronal Cell Lines (2000) (42)
- Aging and Reproduction: Comparative Endocrinology of the Common Tern and Japanese Quail (1995) (42)
- Ovarian aging in developmental and evolutionary contexts (2010) (42)
- Differential patterns of age-related mortality increase in middle age and old age. (2003) (42)
- Neuroendocrine mechanisms and aging. (1979) (42)
- Microglia and Aging in the Brain (2002) (41)
- Astrocytic messenger RNA responses to striatal deafferentation in male rat (1993) (40)
- Impact papers on aging in 2009 (2010) (40)
- Why did ancient people have atherosclerosis?: from autopsies to computed tomography to potential causes. (2014) (39)
- Traffic-related air pollution and brain development (2015) (39)
- Glycine N-Methyltransferase is a Regulatory Enzyme which Increases in Ageing Animals (1973) (39)
- Pituitary tumorigenesis in aging female C57BL/6J mice: A light and electron microscopic study (1981) (38)
- Prolonged gestation, elevated preparturitional plasma progesterone and reproductive aging in C57BL/6J mice. (1978) (38)
- The regulation of luteinizing hormone and prolactin in C57BL/6J mice: effects of estradiol implant size, duration of ovariectomy, and aging. (1984) (37)
- Inflammatory Gene Variants in the Tsimane, an Indigenous Bolivian Population with a High Infectious Load (2011) (36)
- Aging and unusual catecholamine-containing structures in the mouse brain (1979) (36)
- Progesterone antagonism of neurite outgrowth depends on microglial activation via Pgrmc1/S2R. (2013) (35)
- Hematologic and serum electrolyte values of the C57BL-6J male mouse in maturity and senescence. (1973) (35)
- Spontaneous pituitary tumorigenesis and plasma oestradiol in ageing female C57BL/6J mice (1980) (35)
- Amyloid precursor protein mRNA encoding the Kunitz protease inhibitor domain is increased by kainic acid-induced seizures in rat hippocampus (1992) (35)
- Perforant Path Transection Induces Complement C9 Deposition in Hippocampus (1996) (34)
- Rapid corticosterone-induced changes in gene expression in rat hippocampus display type II glucocorticoid receptor specificity. (1988) (34)
- Nanoparticulate matter exposure results in neuroinflammatory changes in the corpus callosum (2018) (34)
- COMMITTEE ON POPULATION (1997) (34)
- Disappearance of GAD-mRNA and tyrosine hydroxylase in substantia nigra following striatal ibotenic acid lesions: Evidence for transneuronal regression (1991) (33)
- Age-related changes in the decidual response of the C57BL/6J mouse uterus. (1977) (33)
- Combined in situ hybridization and immunocytochemistry in the assay of pharmacological effects on tyrosine hydroxylase mRNA concentration. (1989) (33)
- The Exposome in Human Evolution: From Dust to Diesel (2019) (33)
- Variations of Synaptotagmin I, Synaptotagmin IV, and Synaptophysin mRNA Levels in Rat Hippocampus during the Estrous Cycle (1999) (33)
- Inflammatory mechanisms and anti-inflammatory therapy in Alzheimer's disease (1996) (33)
- Gene Products of Corticosteroid Action in Hippocampus a (1994) (32)
- The use of ammonium acetate in the precipitation of ribonucleic acid. (1975) (32)
- Is atherosclerosis fundamental to human aging? Lessons from ancient mummies. (2014) (31)
- Oral administration of estradiol to young C57BL/6J mice induces age-like neuroendocrine dysfunctions in the regulation of estrous cycles. (1989) (31)
- Scavenger receptor mRNAs in rat brain microglia are induced by kainic acid lesioning and by cytokines (1997) (31)
- Aging attenuates redox adaptive homeostasis and proteostasis in female mice exposed to traffic‐derived nanoparticles (‘vehicular smog’) (2018) (31)
- Enlarged seminal vesicles of senescent C57BL-6J mice. (1974) (31)
- Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction☆ (2013) (31)
- Cell resilience in species life spans: a link to inflammation? (2010) (31)
- Neuroendocrine and autonomic functions in aging mammals (1985) (30)
- Relevance of 'adaptive' mutations arising in non-dividing cells of microorganisms to age-related changes in mutant phenotypes of neurons. (1997) (30)
- Equine estrogens induce apolipoprotein E and glial fibrillary acidic protein in mixed glial cultures (2002) (30)
- Intergenerational Relations and the Elderly (1997) (30)
- Expression of complement C1gB and C4 mRNAs during rat brain development (1994) (30)
- Evolutionary perspectives on amyloid and inflammatory features of Alzheimer disease (1996) (29)
- Senescent change in tissue weight and immunoreactive β-endorphin, enkephalin, and vasopressin in eight regions of C57BL/6J mouse brain and pituitary (1985) (29)
- THE SEQUENCE COMPLEXITY OF BRAIN RIBONUCLEIC ACIDS (1982) (27)
- Expression of vimentin increases in the hippocampus and cerebral cortex after entorhinal cortex lesioning and in response to transforming growth factor β 1 (1995) (27)
- Age increase of estrogen receptor-α (ERα) in cortical astrocytes impairs neurotrophic support in male and female rats. (2013) (27)
- Methylation of the rat glial fibrillary acidic protein gene shows tissue‐specific domains (1994) (26)
- Progesterone influence on neurite outgrowth involves microglia. (2009) (26)
- Transforming growth factor-beta 1 induces neuronal and astrocyte genes: tubulin alpha 1, glial fibrillary acidic protein and clusterin. (1994) (26)
- Caliban's heritance and the genetics of neuronal aging (2004) (26)
- The ApoE Locus and COVID-19: Are We Going Where We Have Been? (2020) (25)
- Atherosclerotic cardiovascular disease in Egyptian women: 1570 BCE-2011 CE. (2013) (25)
- Delayed anovulatory syndrome induced by estradiol in female C57BL/6J mice: age-like neuroendocrine, but not ovarian, impairments. (1985) (25)
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- A CROSS-SPECIES AND CROSS-NATIONAL EXAMINATION OF SEX DIFFERENCES IN HEALTHY AGING (2017) (0)
- A NOVEL PHARMACOLOGICAL INTERVENTION TO NEUROINFLAMMATORY OUTCOMES OF AIR POLLUTION: THE GAMMA SECRETASE MODULATOR BPN-15606 ATTENUATED MICROGLIAL AND AMYLOID INDUCTION BY URBAN NANO-PARTICULATE (NPM) IN YOUNG MALE C57BL/6J MICE (2019) (0)
- Plasticity and Aging (1999) (0)
- Proposal to Sequence Genomes of Unique Interest for Research on Aging: Heterocephalus glaber, Cebus capucinus, and Balaena mysticetus (2007) (0)
- Studies on the biochemistry of the brain during aging. (1980) (0)
- The 15th Annual RAND Summer Institute Video (2009) (0)
- Dining with Roy (2004) (0)
- Air Pollution, Aging and Lifespan: Air Pollution Inside and Out Accelerates Aging (2019) (0)
- ApoE4 is associated with lower antioxidant levels and increased oxidative damage in human and mouse brain (2022) (0)
- Short-term Diesel Exhaust Exposure Results in Neuroinflammation and White Matter Injury (2021) (0)
- Book Review:Aging and Cell Function. John E. Johnson, Jr. (1985) (0)
- Bluegrass from the Blue Ridge: Country Band Music of Virginia (1970) (0)
- Evolutionary Biology and Age-Related Mortality (1997) (0)
- AIR POLLUTION IN BRAIN AGING AND DEMENTIA (2017) (0)
- 2018 RAND Summer Institute Lecture Series (2018) (0)
- Introduction: Collecting Biological Indicators in Household Surveys (2000) (0)
- Alzheimer brains: increased soluble amyloid peptides, but decreased lipid rafts (2022) (0)
- Protection against APOE4-associated aging phenotypes with a longevity-promoting intervention (2021) (0)
- Commentary (1994) (0)
- Air pollution nanoparticle exposure reduces neurotrophin signaling and causes hippocampal neural stem cell quiescence in mouse brain (2022) (0)
- Binding of toxic aoligomers to neuronal cell surface proteins (1997) (0)
- Changes in alpha-macroglobulin during malaria in the duckling. (1966) (0)
- The Genetic Background of Atherosclerosis in Ancient Mummies (2015) (0)
- Abstract W P239: Exposure to Airborne Particulate Matter from Vehicular Exhaust Results in Progression of Brain Injury Following Experimental Stroke (2015) (0)
- RAND Summer Institute Lecture Series 2015 (2016) (0)
- Neurotransmitters and Receptors (2003) (0)
- Glen Neaves & the Virginia Mountain Boys, Country Blue Grass from South-West Virginia (1976) (0)
- NEURODEGENERATIVE EFFECT OF NANOSIZED URBAN AIRBORNE PARTICULATE MATERIAL (NPM) (2017) (0)
- Abstract TMP54: Carotid Artery Inflammation Following Air Pollution Exposure (2019) (0)
- Nutrition and Infection in the Developmental Influences on Aging (2007) (0)
- Abstract WP18: Nanoparticulate Matter Exposure Induces Mature Oligodendrocyte Cell Death And Promotes Oligodendrocyte Precursor Cell Proliferation (2022) (0)
- Aging Pigments and Membranes (1999) (0)
- NOVEL GAMMA-SECRETASE MODULATOR REGULATES APP PROCESSING AND INFLAMMATORY RESPONSES IN NPM-EXPOSED MICE (2019) (0)
- Age Increase of Estrogen Receptor- (cid:1) (ER (cid:1) ) in Cortical Astrocytes Impairs Neurotrophic Support in Male and Female Rats (2013) (0)
- Airborne Pollutants as Triggers of Parkinson's Disease via the Olfactory System (2018) (0)
- Neural regulatory mechanisms during ageing: R.C. Adelman, J. Roberts, G.T. Baker, III, S.I. Baskin and V.J. Christofalo (Eds.) (Liss, New York, 1981, 230 p., U.S. $ 21.00) (1982) (0)
- Neuroendocrinology and Sleep During Aging (1999) (0)
- Corrigendum to “Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments” (2014) (0)
- Atherosclerosis in contemporary preindustrial populations: does it exist and is it clinically relevant? (2017) (0)
- The Long Thread of GFAP in Aging, Steroids, and Synaptic Plasticity (2004) (0)
- Instability in the Nuclear and Mitochondrial Genomes (1999) (0)
- Aging, Inflammation & the Body Electric (2006) (0)
- Modification of hair regrowth in aging mice. Abstr. (1970) (0)
- Aging in the brain: Evolutionary perspectives (2000) (0)
- Title : Cardiac antioxidant response to air pollution in mice is altered by ApoE alleles and sex (2019) (0)
- Special Report from the Challenging Views of Alzheimer ’ s Disease What is aging ? What is its role in Alzheimer ’ s disease ? What can we do about it ? (2005) (0)
- DEAFFERENTATION IN THE RAT AND IN ALZHEIMER'S DISEASE (1990) (0)
- Globular structure of the amyloid beta protein and their uses (2000) (0)
- Brain slices in vitro. (1975) (0)
- Short-term Diesel Exhaust Exposure Results in Neuroinflammation and White Matter Injury (2021) (0)
- Discussion to ‘Sex differences in the hypothalamus in the different stages of human life’ by Dick F. Swaab et al. (2003) (0)
- P2-201 FLOW CYTOMETRY DETECTION OF MULTIPLE CELLTYPES AND EXOSOMAL ISOLATION FROM AD CORTEX (2019) (0)
- Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity (2023) (0)
- Air Pollution and Cigarettes Cloud Development (2018) (0)
- Porotic cranial lesions in living forager-horticulturalists: theoretical pathways and preliminary evidence (2019) (0)
- Immunolocalization of oligomeric Abeta42 binding to primary mouse hippocampal cells and B103 rat neuroblastoma cells (1999) (0)
- Preface (2004) (0)
- Abstracts of papers presented at the 1992 Meeting on Molecular Biology of Aging, April 22-April 26, 1992 (1992) (0)
- Abstract TP438: Nanoparticulate Matter Exposure Mediates White Matter Changes in a Murine Model (2017) (0)
- ATHEROSCLEROSIS AS MANIFEST BY THORACIC AORTIC CALCIUM: INSIGHTS FROM A REMOTE NATIVE POPULATION WITH EXTREMELY LOW LEVELS OF CORONARY ATHEROSCLEROSIS AND TRADITIONAL CV RISK FACTORS (2018) (0)
- Susan L. Prescott, Origins: Early Life Solutions to the Modern Health Crisis . University of Western Australia Press, Crawley, Western Australia, 379 pages, ISBN: 9781742586700, 2015 (2015) (0)
- Recently decreased association of air pollution with cognitive impairment in a population‐based aging cohort and in a mouse model (2021) (0)
- Urban traffic-derived nanoparticulate matter reduces neurite outgrowth via TNFα in vitro (2016) (0)
- Childhood Obesity in America: Biography of an Epidemic. By Laura Dawes. Cambridge (Massachusetts): Harvard University Press. $45.00. ix + 305 p.; ill.; index. ISBN: 978-0-674-28144-8. 2014. (2015) (0)
- USING COMPUTED TOMOGRAPHY TO ASSESS BRAIN VOLUMETRICS IN AGING (2019) (0)
- Absence of high affinity steroid binding proteins in plasma of mature and old male c57bl/6j mice. Abstr. (1973) (0)
- Alzheimer’s Disease associations of ferritin and glutathione with oxidative damage and neuronal loss (2023) (0)
- Author response: APOE4 is associated with elevated blood lipids and lower levels of innate immune biomarkers in a tropical Amerindian subsistence population (2021) (0)
- Protection against APOE4-associated aging phenotypes with a longevity-promoting intervention (2021) (0)
- MICROGLIAL INTERACTIONS WITH AMYLOID PLAQUES ARE MODULATED BY SEX AND APOE GENOTYPE IN EFAD MICE (2019) (0)
- Foreword (2001) (0)
- Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo (2017) (0)
- 739 Inflammation and Alzheimer's disease. The role of the complement derived anaphylatoxin C5a (1996) (0)
- Reduction of lipid peroxidase levels in EFAD mouse model (2020) (0)
- Cell Differentiation, Extrinsic Factors, and Aging1 (1976) (0)
- CT Evidence of Atherosclerosis in Ancient Mummies: The Horus Study of 220 Mummies from 5 Continents (2015) (0)
- AIR POLLUTION NANOPARTICULATE MATTER CAUSES WHITE MATTER DAMAGE AND MICROGLIAL ACTIVATION IN A MOUSE MODEL (2019) (0)
- Proposal to Sequence an Organism of Unique Interest for Research on Aging : Heterocephalus glaber , the Naked Mole-Rat (2008) (0)
- TRANSCRIPTOMIC PROFILING OF MICROGLIA FROM AN ALZHEIMER'S DISEASE MOUSE MODEL AND FROM HUMAN INDUCED PLURIPOTENT STEM CELLS REVEALS EFFECTS OF THE APOE4 GENOTYPE (2019) (0)
- Particulate matter exposure and chronic cerebral hypoperfusion promote oxidative stress and induce neuronal and oligodendrocyte apoptosis in male mice (2022) (0)
- The Toxic Nature of the Three Smokes (2018) (0)
- Nathan Shock's pioneering analysis of physiological mechanisms in aging (1987) (0)
- β-Amyloid precursor protein (APP) and APP-RNA are rapidly affected by glutamate in cultured neurons (2007) (0)
- Discussion to “Stress and the brain” by Isabella Heuser and Claas-Hinrich Lammers and “Stress and aging: theoretical and empirical challenges for interdisciplinary research” by Jacqui Smith (2003) (0)
- The Nature of Nutrition: A Unifying Framework from Animal Adaptation to Human Obesity. By Stephen J. Simpson and David Raubenheimer. Princeton (New Jersey): Princeton University Press. $49.50. xi + 239 p. + 8 pl.; ill.; index. ISBN: 978-0-691-14565-5. 2012. (2013) (0)
- Comments on review by gash et al. applications of recombinant DNA techniques (1985) (0)
- APOE GENOTYPE AND COGNITIVE PERFORMANCE IN TSIMANE AND MOSETEN OF BOLIVIA (2019) (0)
- Assemblage de protéine amyloide beta globulaire et ses utilisations (2000) (0)
- NSAIDs inhibit the IL-1β-induced IL-6 secretion from human postmortem astrocytes: The involvement of prostaglandin E2 (1997) (0)
- Subject Index Vol. 46, 1987 (1987) (0)
- Eyeblink conditioning induces RNA encoding a CDC2-related kinase, KKIAMRE in the deep cerebellar nuclei (1998) (0)
- P2-081 Caloric restriction slows Aβ-plaque deposition in APPSWE/IND mice (2004) (0)
- The Evolution of Aging: Empirical and Theoretical Perspectives@@@Between Zeus and the Salmon: The Biodemography of Iongevity (1998) (0)
- Decision letter: Comment on 'Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age' (2019) (0)
- Nutrition, Inflammation, and Infection in the Genomics of Lifespan (2019) (0)
- Air Pollution Neurotoxicity in the Adult Brain: Emerging Concepts from Experimental Findings (0)
- Atherosclerosis in ancient mummified human remains: Linking genetic predisposition with the occurrence of calcified plaques (2015) (0)
- Stem cells for all ages, yet hostage to aging. (2016) (0)
- Developmental origins of aging in the brain and blood vessels (2005) (0)
- Imaging Atherosclerosis in Great Apes. (2020) (0)
- Early developmental exposure to air pollution increases the risk of Alzheimers disease and amyloid production: Studies in mouse and Caenorhabditis elegans (2020) (0)
- APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice (2019) (0)
- The Rise and Fall of Excess Male Infant Mortality Extended (2006) (0)
- The age-old problem of mortality (2004) (0)
- Eric Davidson's early years in development. (2016) (0)
- Years of Research Lead to Future Treatments for Alzheimer Disease (2003) (0)
- 805 The regulation of GFAP transcription by estrogens in primary cultured astrocytes as a model for estrogen-glucocorticoid interactions with brain responses to injury during aging and Alzheimer disease (1996) (0)
- TABLE 7-2, A Lexicon of QTL Terminology (1997) (0)
- Brain volume, energy balance, and cardiovascular health in two nonindustrial South American populations. (2023) (0)
- Experimental Manipulations of Brain Aging (1999) (0)
- DOES HYPERTENSION CONTRIBUTE TO CEREBRAL MICROBLEEDS IN ALZHEIMER TRANSGENIC MICE? (2019) (0)
- Gene Activity and Neurodegeneration in the Extrapyramidal System: A Progress Report on Molecular and Morphological Correlates (1990) (0)
- Overview on Aging (1999) (0)
- Book Review:The Physiology and Pathology of Human Aging. Ralph Goldman, Morris Rockstein, Marvin L. Sussman (1976) (0)
- Longevity: The Biology and Demography of Life Span.ByJames R Carey.Princeton (New Jersey): Princeton University Press. $75.00 (hardcover); $29.95 (paper). xxv + 278 p; ill.; index. ISBN: 0–691–08848–9 (hc); 0–691–08849–7 (pb). 2003. (2003) (0)
- CAENORHABDITIS ELEGANS AS A MODEL OF AIR POLLUTION TOXICITY DURING DEVELOPMENT AND LIFESPAN (2019) (0)
- The J aniform genetics of aging (1994) (0)
- Cerebral cortex and blood transcriptome changes in mouse neonates prenatally exposed to air pollution particulate matter (2021) (0)
- Pathway‐based genome analysis of cognitive impairment in a forager‐horticulturalist South American population (2022) (0)
- Figure 10-6, Ache children's food acquisition by age and the availability of fruits (1997) (0)
- HYPERTENSION DOES NOT CONTRIBUTE TO MICROBLEEDS ONSET IN FEMALE EFAD MICE (2019) (0)
- Life course of the brain during normal aging and Alzheimer's disease (2016) (0)
- Third Annual Leonard Berg Symposium: Final Thoughts and Future Directions (2003) (0)
- Reductions in ApoE and GPx4 highlight the Alzheimer’s disease lipid raft vulnerability (2021) (0)
- Discussion to ‘Neurons, glia, and plasticity in normal brain aging’ by Caleb E. Finch and ‘Normal brain aging: a commentary’ by Olivier Toussaint (2003) (0)
- Author response: Mouse brain transcriptome responses to inhaled nanoparticulate matter differed by sex and APOE in Nrf2-Nfkb interactions (2020) (0)
- Amyloid beta-protein (glubulær collection and uses thereof) (1998) (0)
- Ovarian and Steroidal Influences on Neuroendocrine Aging Processes in Female Rodents (2002) (0)
- Impact papers on aging in 2009 Citation (2022) (0)
- SHORT-TERM DIESEL EXHAUST PARTICLE NEUROTOXICITY MEDIATED BY TLR4 ACROSS AGE AND SEX (2022) (0)
- Discussion to ‘Imaging methods for evaluating brain function in man’ by Robert M. Kessler (2003) (0)
- Inhibiting Bach1 enhanced the activation of Nrf2 signaling and the degradation of HNE in response to oxidative stress (2020) (0)
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