Carl F. Nathan
#20,474
Most Influential Person Now
American microbiologist and immunologist
Carl F. Nathan's AcademicInfluence.com Rankings
Carl F. Nathanbiology Degrees
Biology
#887
World Rank
#1552
Historical Rank
#474
USA Rank
Immunology
#23
World Rank
#26
Historical Rank
#10
USA Rank
Microbiology
#17
World Rank
#28
Historical Rank
#12
USA Rank
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Biology
Carl F. Nathan's Degrees
- Bachelors Biochemistry University of California, Berkeley
- Masters Medicine Harvard University
Why Is Carl F. Nathan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Carl F. Nathan is the chair of the department of microbiology and immunology at Weill Cornell Medicine and a former dean of the Weill Graduate School of Medical Sciences at Cornell University. Some of his most notable work has been in the characterization of IFNγ, TGF-β, and TNFα in immunology. The Nathan lab studies the immune response to M. tuberculosis.
Carl F. Nathan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Nitric oxide and macrophage function. (1997) (4151)
- Nitric oxide synthases: Roles, tolls, and controls (1994) (2979)
- Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. (1988) (2910)
- Neutrophils and immunity: challenges and opportunities (2006) (2700)
- Secretory products of macrophages. (1987) (2684)
- Points of control in inflammation (2002) (2566)
- Nitric oxide as a secretory product of mammalian cells (1992) (2565)
- Production of large amounts of hydrogen peroxide by human tumor cells. (1991) (2325)
- Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. (1994) (2218)
- Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. (1992) (1904)
- Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells (1989) (1769)
- Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity (1983) (1730)
- Regulation of biosynthesis of nitric oxide. (1994) (1713)
- Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase (1995) (1544)
- Role of nitric oxide synthesis in macrophage antimicrobial activity. (1991) (1525)
- Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. (2000) (1436)
- Nonresolving Inflammation (2010) (1365)
- Macrophage deactivation by interleukin 10 (1991) (1302)
- Identification of nitric oxide synthase as a protective locus against tuberculosis. (1997) (1156)
- Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide (1993) (1140)
- Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages (2003) (1083)
- Beyond oxidative stress: an immunologist's guide to reactive oxygen species (2013) (1076)
- Inducible nitric oxide synthase: what difference does it make? (1997) (958)
- Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase. (1993) (854)
- Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes. (1987) (841)
- Cytokines in context (1991) (840)
- Deactivation of macrophages by transforming growth factor-β (1988) (838)
- Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein. (1991) (794)
- Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta (1993) (713)
- Suppression of arthritis by an inhibitor of nitric oxide synthase (1993) (691)
- Peroxynitrite reductase activity of bacterial peroxiredoxins (2000) (671)
- Calmodulin is a subunit of nitric oxide synthase from macrophages (1992) (642)
- The macrophage as an effector cell. (1980) (629)
- Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins (1989) (602)
- Conversion of Proepithelin to Epithelins Roles of SLPI and Elastase in Host Defense and Wound Repair (2002) (595)
- Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10. (1992) (570)
- Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties (1988) (568)
- Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase. (1999) (560)
- Gram‐negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction 1 (1991) (552)
- N omega-hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine. (1991) (543)
- Extracellular cytolysis by activated macrophages and granulocytes. II. Hydrogen peroxide as a mediator of cytotoxicity (1979) (537)
- Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages. (1989) (529)
- The high‐output nitric oxide pathway: role and regulation (1994) (528)
- dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway (2012) (526)
- Role of interferon regulatory factor 1 in induction of nitric oxide synthase (1994) (521)
- Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis (1996) (520)
- Glutathione metabolism as a determinant of therapeutic efficacy: a review. (1984) (520)
- Hydrogen peroxide release from mouse peritoneal macrophages: dependence on sequential activation and triggering (1977) (500)
- The Proteasome of Mycobacterium tuberculosis Is Required for Resistance to Nitric Oxide (2003) (491)
- Essential Role of Induced Nitric Oxide in the Initiation of the Inflammatory Response after Hemorrhagic Shock (1998) (489)
- ALTERATIONS OF MACROPHAGE FUNCTIONS BY MEDIATORS FROM LYMPHOCYTES (1971) (488)
- Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide (1991) (451)
- Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide (1989) (451)
- Macrophage Microbicidal Mechanisms In Vivo: Reactive Nitrogen versus Oxygen Intermediates in the Killing of Intracellular Visceral Leishmania donovani (1999) (444)
- Shedding of tumor necrosis factor receptors by activated human neutrophils (1990) (439)
- Modulation of Macrophage Function by Transforming Growth Factor β, Interleukin‐4, and Interleukin‐10 a (1993) (439)
- Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide (1979) (438)
- Reprogramming of the Macrophage Transcriptome in Response to Interferon-γ and Mycobacterium tuberculosis (2001) (437)
- Macrophage deactivating factor and transforming growth factors-beta 1 -beta 2 and -beta 3 inhibit induction of macrophage nitrogen oxide synthesis by IFN-gamma. (1990) (418)
- Secretory Leukocyte Protease Inhibitor: A Macrophage Product Induced by and Antagonistic to Bacterial Lipopolysaccharide (1997) (410)
- Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs 1 (1991) (400)
- Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice (2010) (399)
- Identification of arginine as a precursor of endothelium-derived relaxing factor. (1988) (399)
- Antibiotic resistance--problems, progress, and prospects. (2014) (391)
- Periplasmic superoxide dismutase protects Salmonella from products of phagocyte NADPH-oxidase and nitric oxide synthase. (1997) (385)
- Antibiotics at the crossroads (2004) (385)
- Metabolic Enzymes of Mycobacteria Linked to Antioxidant Defense by a Thioredoxin-Like Protein (2002) (377)
- Hydrogen peroxide metabolism in human monocytes during differentiation in vitro. (1981) (371)
- Deactivation of macrophages by transforming growth factor-beta. (1988) (366)
- Activation of human macrophages. Comparison of other cytokines with interferon-gamma (1984) (363)
- Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells (1995) (359)
- Reprogramming of the macrophage transcriptome in response to interferon-gamma and Mycobacterium tuberculosis: signaling roles of nitric oxide synthase-2 and phagocyte oxidase. (2001) (346)
- Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma. (1985) (345)
- Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages. (1998) (340)
- Activation of macrophages in vivo and in vitro. Correlation between hydrogen peroxide release and killing of Trypanosoma cruzi (1979) (336)
- Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond (2016) (324)
- Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment (2003) (316)
- Local and systemic effects of intradermal recombinant interferon-gamma in patients with lepromatous leprosy. (1986) (315)
- Shared actions of endotoxin and taxol on TNF receptors and TNF release. (1990) (313)
- Inducible nitric oxide synthase‐deficient mice have enhanced leukocyte–endothelium interactions in endotoxemia (1997) (304)
- A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis (2008) (302)
- A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity. (1999) (302)
- Bacterial infection induces nitric oxide synthase in human neutrophils. (1997) (299)
- Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates. (2010) (298)
- Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease (1996) (290)
- Peptide methionine sulfoxide reductase: structure, mechanism of action, and biological function. (2002) (285)
- Secretion of pyruvate. An antioxidant defense of mammalian cells (1987) (274)
- Antibiotic proteins of human polymorphonuclear leukocytes. (1989) (272)
- Mechanism of suppression of nitric oxide synthase expression by interleukin‐4 in primary mouse macrophages (1994) (268)
- Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates (1979) (248)
- Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling. (2003) (242)
- Acid Resistance in Mycobacterium tuberculosis (2009) (226)
- Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha. (1995) (225)
- Respiratory burst in adherent human neutrophils: triggering by colony- stimulating factors CSF-GM and CSF-G (1989) (223)
- L-citrulline production from L-arginine by macrophage nitric oxide synthase. The ureido oxygen derives from dioxygen. (1990) (222)
- CHARACTERIZATION OF A LYMPHOCYTE FACTOR WHICH ALTERS MACROPHAGE FUNCTIONS (1973) (221)
- Isocitrate lyase mediates broad antibiotic tolerance in Mycobacterium tuberculosis (2014) (219)
- Glutathione depletion sensitizes tumor cells to oxidative cytolysis. (1982) (217)
- Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide. (1999) (215)
- Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates (2001) (212)
- Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma (1987) (212)
- Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties. (1990) (208)
- MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival (2007) (204)
- Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor necrosis factor (TNF) receptor. Comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils. (1991) (204)
- SnapShot: Reactive Oxygen Intermediates (ROI) (2010) (197)
- Experimental visceral leishmaniasis: production of interleukin 2 and interferon-gamma, tissue immune reaction, and response to treatment with interleukin 2 and interferon-gamma. (1987) (197)
- Role of oxygen-dependent mechanisms in antibody-induced lysis of tumor cells by activated macrophages (1980) (196)
- Inhibitors Selective for Mycobacterial versus Human Proteasomes (2009) (196)
- Rapid Interferon γ–dependent Clearance of Influenza A Virus and Protection from Consolidating Pneumonitis in Nitric Oxide Synthase 2–deficient Mice (1998) (194)
- Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase. (2005) (193)
- Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase (2005) (189)
- Identification of a copper-binding metallothionein in pathogenic mycobacteria. (2008) (187)
- Macrophage activation revisited. (1994) (184)
- Reactive nitrogen intermediates and the pathogenesis of Salmonella and mycobacteria. (2000) (177)
- FAD and GSH participate in macrophage synthesis of nitric oxide. (1990) (174)
- A simple method for counting adherent cells: application to cultured human monocytes, macrophages and multinucleated giant cells. (1983) (173)
- Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils (1990) (169)
- MyD88 Primes Macrophages for Full-Scale Activation by Interferon-γ yet Mediates Few Responses to Mycobacterium tuberculosis (2003) (167)
- Mycobacterium tuberculosis and the host response (2005) (164)
- Selective killing of nonreplicating mycobacteria. (2008) (161)
- A glutamate‐alanine‐leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP (2005) (157)
- Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia. (2010) (156)
- S-nitroso proteome of Mycobacterium tuberculosis: Enzymes of intermediary metabolism and antioxidant defense. (2005) (156)
- A semi-automated micro-assay for H2O2 release by human blood monocytes and mouse peritoneal macrophages. (1985) (156)
- Transcription and translation of inducible nitric oxide synthase in the pancreas of prediabetic BB rats (1993) (156)
- Tumor necrosis factor and CD11/CD18 (beta 2) integrins act synergistically to lower cAMP in human neutrophils (1990) (153)
- Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates (1985) (151)
- Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. (2011) (151)
- Secretion of oxygen intermediates: role in effector functions of activated macrophages. (1982) (150)
- Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF. (1999) (148)
- Molecular mechanisms in tumor-cell killing by activated macrophages. (1983) (145)
- Fresh Approaches to Anti-Infective Therapies (2012) (143)
- Vesicle membrane association of nitric oxide synthase in primary mouse macrophages. (1995) (143)
- Inactivation of nitric oxide synthase after prolonged incubation of mouse macrophages with IFN-gamma and bacterial lipopolysaccharide. (1994) (142)
- Synthesis of nitrogen oxides from L-arginine by macrophage cytosol: requirement for inducible and constitutive components. (1989) (140)
- Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin) (1993) (140)
- Acid-Susceptible Mutants of Mycobacterium tuberculosis Share Hypersusceptibility to Cell Wall and Oxidative Stress and to the Host Environment (2008) (137)
- Role of nitric oxide in antagonistic effects of transforming growth factor-beta and interleukin-1 beta on the beating rate of cultured cardiac myocytes. (1992) (135)
- Mechanisms of macrophage antimicrobial activity. (1983) (135)
- Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue (2004) (125)
- Enzymatic basis of macrophage activation. Kinetic analysis of superoxide production in lysates of resident and activated mouse peritoneal macrophages and granulocytes. (1984) (123)
- Phase I trial of recombinant interferon gamma in cancer patients. (1986) (123)
- Epidemic Inflammation: Pondering Obesity (2008) (122)
- Induction of ER Stress in Macrophages of Tuberculosis Granulomas (2010) (121)
- Downregulation of tumor necrosis factor receptors on macrophages and endothelial cells by microtubule depolymerizing agents (1990) (121)
- Macrophages rapidly internalize their tumor necrosis factor receptors in response to bacterial lipopolysaccharide. (1989) (121)
- Role for Nucleotide Excision Repair in Virulence of Mycobacterium tuberculosis (2005) (121)
- Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate (2006) (120)
- Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon-gamma and bacterial lipopolysaccharide. (1993) (119)
- Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes. (2011) (119)
- A Novel Antioxidant Gene from Mycobacterium tuberculosis (1997) (118)
- Evaluation of bacterial survival and phagocyte function with a fluorescence-based microplate assay (1997) (117)
- Liver macrophages in murine listeriosis. Cell-mediated immunity is correlated with an influx of macrophages capable of generating reactive oxygen intermediates (1985) (116)
- Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistance. (2009) (115)
- Lipopolysaccharide-Related Stimuli Induce Expression of the Secretory Leukocyte Protease Inhibitor, a Macrophage-Derived Lipopolysaccharide Inhibitor (1998) (114)
- Administration of recombinant interferon gamma to cancer patients enhances monocyte secretion of hydrogen peroxide. (1985) (114)
- Taxol shares the ability of bacterial lipopolysaccharide to induce tyrosine phosphorylation of microtubule-associated protein kinase. (1993) (114)
- Role of iNOS in Human Host Defense (2006) (110)
- Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase. (2010) (108)
- Role of activated macrophages in antibody-dependent lysis of tumor cells (1980) (104)
- Lymphokines enhance the capacity of human monocytes to secret reactive oxygen intermediates. (1982) (103)
- Beta 2 integrin-dependent tyrosine phosphorylation of paxillin in human neutrophils treated with tumor necrosis factor (1994) (103)
- TREM-1: A new regulator of innate immunity in sepsis syndrome (2001) (101)
- Mycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificity (2006) (100)
- Peroxide and pteridine: a hypothesis on the regulation of macrophage antimicrobial activity by interferon gamma. (1986) (98)
- Mycobacterium tuberculosis appears to lack α‐ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes (2005) (95)
- Respiratory burst in adherent human neutrophils: triggering by colony-stimulating factors CSF-GM and CSF-G. (1989) (94)
- In vitro differentiation of human macrophages with enhanced antimycobacterial activity. (2011) (94)
- Inducible Nitric Oxide Synthase Requires Both the Canonical Calmodulin-binding Domain and Additional Sequences in Order to Bind Calmodulin and Produce Nitric Oxide in the Absence of Free Ca2+* (1996) (94)
- Putting the brakes on innate immunity: a regulatory role for CD200? (2001) (91)
- Nitazoxanide Disrupts Membrane Potential and Intrabacterial pH Homeostasis of Mycobacterium tuberculosis. (2011) (91)
- Elevation of IL-18 in Human Sepsis (2000) (90)
- Does endothelium-derived nitric oxide have a role in cytokine-induced hypotension? (1990) (90)
- Macrophage oxygen-dependent antimicrobial activity. IV. Role of endogenous scavengers of oxygen intermediates (1980) (90)
- Targeting Phenotypically Tolerant Mycobacterium tuberculosis. (2017) (86)
- Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells. (2015) (83)
- Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials (2012) (82)
- Trace levels of bacterial lipopolysaccharide prevent interferon-gamma or tumor necrosis factor-alpha from enhancing mouse peritoneal macrophage respiratory burst capacity. (1987) (80)
- Mechanisms and modulation of macrophage activation. (1991) (80)
- Mycobacterium tuberculosis expresses methionine sulphoxide reductases A and B that protect from killing by nitrite and hypochlorite (2009) (79)
- Differential stimulation of murine lymphoma growth in vitro by normal and BCG-activated macrophages (1975) (79)
- Functional channel formation associated with cytotoxic T-cell granules. (1986) (78)
- Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta (1988) (78)
- Characterization of the nonphagocytic adherent cell from the peritoneal cavity of normal and BCG-treated mice. (1977) (77)
- Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis (2013) (76)
- Secretion of toxic oxygen products by macrophages: regulatory cytokines and their effects on the oxidase. (1986) (76)
- Nitrite produced by Mycobacterium tuberculosis in human macrophages in physiologic oxygen impacts bacterial ATP consumption and gene expression (2013) (75)
- N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis (2016) (75)
- Hydrogen peroxide release by alveolar macrophages from sarcoid patients and by alveolar macrophages from normals after exposure to recombinant interferons alpha A, beta, and gamma and 1,25-dihydroxyvitamin D3. (1987) (74)
- Identification of Nitric Oxide Synthase 2 as an Innate Resistance Locus against Ectromelia Virus Infection (1998) (73)
- Complementation analysis of mutants of nitric oxide synthase reveals that the active site requires two hemes. (1996) (72)
- noxR3, a Novel Gene fromMycobacterium tuberculosis, Protects Salmonella typhimurium from Nitrosative and Oxidative Stress (1999) (71)
- Resistance of human tumor cells in vitro to oxidative cytolysis. (1985) (70)
- Lung surfactant and reactive oxygen-nitrogen species: antimicrobial activity and host-pathogen interactions. (2001) (70)
- Carboxyl terminus of inducible nitric oxide synthase. Contribution to NADPH binding and enzymatic activity. (1994) (70)
- Inducible nitric oxide synthase: identification of amino acid residues essential for dimerization and binding of tetrahydrobiopterin. (1995) (70)
- Suppression of macrophage oxidative metabolism by products of malignant and nonmalignant cells (1982) (70)
- Activation of mouse peritoneal macrophages by monoclonal antibodies to Mac-1 (complement receptor type 3) (1987) (69)
- Cellular responses to the intradermal injection of recombinant human gamma-interferon in lepromatous leprosy patients. (1987) (69)
- Secretory leukocyte protease inhibitor, an inhibitor of neutrophil activation, is elevated in serum in human sepsis and experimental endotoxemia (2000) (69)
- Resisting antimicrobial resistance (2020) (68)
- Biology of antimicrobial resistance and approaches to combat it (2020) (67)
- Immunology: Oxygen and the inflammatory cell (2003) (67)
- Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils (2005) (67)
- Structural insights on the Mycobacterium tuberculosis proteasomal ATPase Mpa. (2009) (67)
- Killing of non-replicating Mycobacterium tuberculosis by 8-hydroxyquinoline. (2010) (66)
- Traces of bacterial lipopolysaccharide suppress IFN-gamma-induced nitric oxide synthase gene expression in primary mouse macrophages. (1993) (66)
- Inducible nitric oxide synthase in the tuberculous human lung. (2002) (65)
- Adenosine regulates the respiratory burst of cytokine-triggered human neutrophils adherent to biologic surfaces. (1989) (65)
- Critical Role of the Carboxyl Terminus of Proline-rich Tyrosine Kinase (Pyk2) in the Activation of Human Neutrophils by Tumor Necrosis Factor (2003) (62)
- ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB (2018) (61)
- Synthetic calanolides with bactericidal activity against replicating and nonreplicating Mycobacterium tuberculosis. (2014) (59)
- Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations (2017) (59)
- Complementary DNA sequence of human neutrophil azurocidin, an antibiotic with extensive homology to serine proteases. (1991) (58)
- Metchnikoff's Legacy in 2008 (2008) (58)
- Fellutamide B is a potent inhibitor of the Mycobacterium tuberculosis proteasome. (2010) (56)
- A philosophy of anti-infectives as a guide in the search for new drugs for tuberculosis. (2008) (55)
- Hydrogen peroxide and cytolytic factor can interact synergistically in effecting cytolysis of neoplastic targets. (1981) (54)
- Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance (2018) (53)
- Isolation of a complementary DNA clone encoding a precursor to human eosinophil major basic protein (1988) (53)
- E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress (2015) (53)
- Inhibition of glutathione synthesis augments lysis of murine tumor cells by sulfhydryl-reactive antineoplastics. (1983) (53)
- Interactions of bacterial lipopolysaccharide with microtubule proteins. (1992) (52)
- Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis (2013) (52)
- Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice (2016) (51)
- Subcellular location and properties of bactericidal factors from human neutrophils (1986) (50)
- Aligning pharmaceutical innovation with medical need (2007) (50)
- The profit problem in antibiotic R&D (2005) (49)
- Distinct Specificities of Mycobacterium tuberculosis and Mammalian Proteasomes for N-Acetyl Tripeptide Substrates* (2008) (49)
- Identification of Mycobacterium tuberculosis Counterimmune (cim) Mutants in Immunodeficient Mice by Differential Screening (2004) (49)
- Macrophage deactivation. Altered kinetic properties of superoxide- producing enzyme after exposure to tumor cell-conditioned medium (1986) (48)
- N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets. (2013) (48)
- Decreased phagocytosis by peritoneal macrophages from BCG-treated mice: induction of the phagocytic defect in normal macrophages with BCG in vitro. (1977) (48)
- SARM Is Required for Neuronal Injury and Cytokine Production in Response to Central Nervous System Viral Infection (2013) (47)
- Nonredundant Antioxidant Defense by Multiple Two-Cysteine Peroxiredoxins in Human Prostate Cancer Cells (2002) (47)
- Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition (2019) (46)
- A multi-stress model for high throughput screening against non-replicating Mycobacterium tuberculosis. (2015) (45)
- Hemorrhagic tumor necrosis during a pilot trial of tumor necrosis factor-alpha and anti-GD3 ganglioside monoclonal antibody in patients with metastatic melanoma (1994) (44)
- Taming tuberculosis: a challenge for science and society. (2009) (44)
- Release of arachidonate and reduction of oxygen. Independent metabolic bursts of the mouse peritoneal macrophage. (1986) (43)
- Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes (2017) (43)
- Isolation of a subpopulation of adherent peritoneal cells with anti-tumour activity (1976) (42)
- Man is not a mouse: reply (2007) (42)
- Treatment of patients with chronic granulomatous disease with recombinant human interferon‐gamma does not improve neutrophil oxidative metabolism, cytochrome b558 content or levels of four anti‐microbial proteins (1992) (42)
- Lethality of endotoxin in mice genetically deficient in the respiratory burst oxidase, inducible nitric oxide synthase, or both. (1999) (41)
- The Moving Frontier in Nitric Oxide–Dependent Signaling (2004) (41)
- Peptidomimetic Fluoromethylketone Rescues Mice from Lethal Endotoxic Shock (1999) (40)
- TB drug development: immunology at the table (2015) (39)
- Improved Control of Tuberculosis and Activation of Macrophages in Mice Lacking Protein Kinase R (2012) (39)
- Oxathiazolones Selectively Inhibit the Human Immunoproteasome over the Constitutive Proteasome. (2014) (39)
- Suppression of macrophage responses to bacterial lipopolysaccharide by a non-secretory form of secretory leukocyte protease inhibitor. (1999) (39)
- Nitrite production by stimulated human polymorphonuclear leukocytes supplemented with azide and catalase. (1993) (38)
- Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis (2017) (38)
- Analysis of the nonfunctional respiratory burst in murine Kupffer cells (1988) (38)
- Suppression of macrophage antimicrobial activity by a tumor cell product. (1983) (37)
- Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis (2016) (37)
- Cytokine regulation of nitric oxide synthase in mouse retinal pigment epithelial cells in culture. (1994) (37)
- Comparison of transforming growth factor-beta and a macrophage- deactivating polypeptide from tumor cells. Differences in antigenicity and mechanism of action. (1989) (37)
- Identification of Novel Anti-mycobacterial Compounds by Screening a Pharmaceutical Small-Molecule Library against Nonreplicating Mycobacterium tuberculosis. (2015) (36)
- Effect of recombinant interferon-gamma on hydrogen peroxide-releasing capacity of monocyte-derived macrophages from patients with lepromatous leprosy. (1986) (36)
- Antimicrobial mechanisms of macrophages (1992) (34)
- Type I interferon signaling mediates Mycobacterium tuberculosis–induced macrophage death (2020) (34)
- Role of oxygen in T cell-mediated cytolysis. (1982) (34)
- Plague prevention and politics in Manchuria, 1910-1931 (1967) (33)
- Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK (2016) (33)
- Neutrophils and COVID-19: Nots, NETs, and knots (2020) (33)
- Efficacy of Nitazoxanide against Clinical Isolates of Mycobacterium tuberculosis (2013) (32)
- Rapid, Semiquantitative Assay To Discriminate among Compounds with Activity against Replicating or Nonreplicating Mycobacterium tuberculosis (2015) (32)
- Benzimidazole-based compounds kill Mycobacterium tuberculosis. (2014) (32)
- Dependence on Sequential Activation and Triggering (1977) (32)
- New Approaches to Filling the Gap in Tuberculosis Drug Discovery (2007) (32)
- Crystal Structure and Functional Analysis of Lipoamide Dehydrogenase from Mycobacterium tuberculosis* (2005) (31)
- Catalytic Antibody Bridges Innate and Adaptive Immunity (2002) (31)
- Widespread intradermal accumulation of mononuclear leukocytes in lepromatous leprosy patients treated systemically with recombinant interferon gamma (1990) (31)
- Phase I trial of recombinant interferon gamma by 1-hour i.v. infusion. (1986) (31)
- Cooperative development of antimicrobials: looking back to look ahead (2015) (30)
- Effects of reagent and cell-generated hydrogen peroxide on the properties of low density lipoprotein. (1986) (30)
- Identification of a Chemical That Inhibits the Mycobacterial UvrABC Complex in Nucleotide Excision Repair† (2011) (29)
- Mobilizable intracellular pool of p55 (type I) tumor necrosis factor receptors in human neutrophils (1992) (29)
- Target-Based Screen Against a Periplasmic Serine Protease That Regulates Intrabacterial pH Homeostasis in Mycobacterium tuberculosis (2014) (28)
- Inducible nitric oxide synthase: regulation subserves function. (1995) (28)
- Paradoxical preservation of a lipopolysaccharide response in C3H/HeJ macrophages: induction of matrix metalloproteinase-9. (1999) (26)
- Fatal Cytomegalovirus Infection in an Adult with Inherited NOS2 Deficiency. (2020) (26)
- The Release of Hydrogen Peroxide from Mononuclear Phagocytes and its Role in Extracellular Cytolysis (1980) (26)
- Immunoproteasome β5i‐Selective Dipeptidomimetic Inhibitors (2016) (26)
- Genome-Wide Screen for Mycobacterium tuberculosis Genes That Regulate Host Immunity (2010) (26)
- Hydrogen peroxide from cellular metabolism of cystine. A requirement for lysis of murine tumor cells by vernolepin, a glutathione-depleting antineoplastic. (1985) (25)
- Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase . (2010) (24)
- Coordinate Actions of Growth Factors in Monocytes/Macrophages (1990) (24)
- Secretory products of macrophages: twenty-five years on. (2012) (23)
- Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment (2018) (22)
- New Evidence for the Complexity of the Population Structure of Mycobacterium tuberculosis Increases the Diagnostic and Biologic Challenges. (2016) (22)
- Relationship between extracellular stimulation of intracellular killing and oxygen-dependent microbicidal systems of monocytes (1985) (22)
- Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis (2018) (21)
- Influence of Allosteric Regulators on Individual Steps in the Reaction Catalyzed by Mycobacterium tuberculosis 2-Hydroxy-3-oxoadipate Synthase* (2013) (21)
- The Tuberculosis Drug Accelerator at year 10: what have we learned? (2021) (20)
- Identification of new inhibitors of protein kinase R guided by statistical modeling. (2011) (19)
- Nitrite impacts the survival of Mycobacterium tuberculosis in response to isoniazid and hydrogen peroxide (2013) (19)
- Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis (2021) (19)
- Hemorrhagic tumor necrosis during a pilot trial of tumor necrosis factor-alpha and anti-GD3 ganglioside monoclonal antibody in patients with metastatic melanoma. (1994) (19)
- RELEASE OF HYDROGEN PEROXIDE (1981) (18)
- Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome. (2017) (18)
- Making space for anti-infective drug discovery. (2011) (18)
- Nitric oxide and biopterin: a study in Chiaroscuro. (1994) (18)
- An Antibiotic Mimics Immunity (2008) (18)
- Echocardiographic and survival studies in mice undergoing endotoxic shock: effects of genetic ablation of inducible nitric oxide synthase and pharmacologic antagonism of platelet-activating factor. (1999) (17)
- Hydrogen Peroxide Release by Alveolar Macrophages from Sarcoid Patients and by Alveolar Macrophages from Normals after Exposure to Recombinant Interferons aA, fl, and y and 1 ,25-Dihydroxyvitamin D3 (17)
- Cryptococcal osteomyelitis treated with 5-fluorocytosine. (1974) (16)
- Is iNOS Beginning to Smoke? (2011) (16)
- Ceramide selectively inhibits early events in the response of human neutrophils to tumor necrosis factor (1996) (16)
- Bacillus Calmette-Guerin-activated murine macrophages kill syngeneic melanoma cells under strict anaerobic conditions (1984) (16)
- Cytosolic Phospholipase A2 Enzymes Are Not Required by Mouse Bone Marrow-Derived Macrophages for the Control of Mycobacterium tuberculosis In Vitro (2006) (16)
- Early Bactericidal Activity Trial of Nitazoxanide for Pulmonary Tuberculosis (2020) (16)
- Macrophage activation: some questions. (1986) (16)
- Multiform antimicrobial resistance from a metabolic mutation (2021) (15)
- Progress and new directions in genetics of tuberculosis: an NHLBI working group report. (2005) (15)
- The measurement of cytochrome b559 in polymorphonuclear leukocytes and macrophages in the presence of hemoglobin or mitochondrial cytochromes. (1988) (15)
- Selective Phenylimidazole-based Inhibitors of the Mycobacterium tuberculosis Proteasome. (2019) (15)
- Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase. (2013) (15)
- Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome. (2017) (15)
- Inhibition of Glutathione Synthesis (1983) (14)
- Nonresolving inflammation redux (2022) (14)
- N-iminoethyl-l-lysine improves memory and reduces amyloid pathology in a transgenic mouse model of amyloid deposition (2010) (13)
- Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis (2015) (13)
- Chemical inhibitors of TNF signal transduction in human neutrophils point to distinct steps in cell activation (2006) (13)
- Development of a highly selective Plasmodium falciparum proteasome inhibitor with anti-malaria activity in humanized mice. (2021) (13)
- In vivo killing of intracellular visceral Leishmania donovani by a macrophage-targeted hydrogen peroxide-generating system. (1988) (13)
- Macrophages' Choice: Take It In or Keep It Out. (2016) (11)
- Inducible Nitric Oxide Synthase Requires Both the Canonical Calmodulin-binding Domain and Additional Sequences in Order to Bind Calmodulin and Produce Nitric Oxide in the Absence of Free Ca 2 (1996) (11)
- Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis (2018) (11)
- Visualization of the Charcoal Agar Resazurin Assay for Semi-quantitative, Medium-throughput Enumeration of Mycobacteria (2016) (10)
- From transient infection to chronic disease (2015) (10)
- Characterization of Differentially Detectable Mycobacterium tuberculosis in the Sputum of Subjects with Drug-Sensitive or Drug-Resistant Tuberculosis before and after Two Months of Therapy (2021) (10)
- Immune response during HIV and tuberculosis co-infection. (1998) (9)
- Immunology. Catalytic antibody bridges innate and adaptive immunity. (2002) (9)
- A Macrophage Product Responsible for Cytostasis and Respiratory (1989) (9)
- Nonredundant functions of Mycobacterium tuberculosis chaperones promote survival under stress (2020) (9)
- Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis. (2019) (9)
- Evidence for dispensability of protein kinase R in host control of tuberculosis (2018) (9)
- Rethinking immunology (2021) (9)
- Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in Mycobacterium tuberculosis. (2019) (8)
- AGONIST AND ANTAGONIST EFFECTS OF INTERFERON a AND # ON ACTIVATION OF HUMAN MACROPHAGES Two Classes of Interferon y Receptors and Blockade of the High-Affinity Sites by Interferon a or (8)
- Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected (2021) (8)
- Inducible Nitric Oxide Synthase Requires Both the Canonical Calmodulin-binding Domain and Additional Sequences in Order to Bind Calmodulin and Produce Nitric Oxide in the Absence of Free Ca* (1996) (8)
- A protecting group-free synthesis of deazathiamine: a step toward inhibitor design. (2010) (8)
- Correction: Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis (2013) (8)
- Drug-resistant tuberculosis: a new shot on goal (2014) (7)
- Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions (2022) (7)
- Grobmyer, S. R. et al. Peptidomimetic fluoromethylketone rescues mice from lethal endotoxic shock: Paradoxical increase in products of caspase 1 (ICE). Mol. Med. 5, 585−594 (1999) (7)
- Regulation of macrophage oxidative metabolism and antiparasitic activity (1985) (7)
- Mycobacterium tuberculosis gene Rv2136c is dispensable for acid resistance and virulence in mice. (2011) (7)
- Kunkel Lecture: Fundamental immunodeficiency and its correction (2017) (7)
- Structure-Activity Relationships of Noncovalent Immunoproteasome β5i-Selective Dipeptides. (2020) (7)
- Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA (2019) (6)
- Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome. (2021) (6)
- Identification of genes involved in innate responsiveness to bacterial products by differential display. (1998) (6)
- Activity-Based Protein Profiling Reveals That Cephalosporins Selectively Active on Non-replicating Mycobacterium tuberculosis Bind Multiple Protein Families and Spare Peptidoglycan Transpeptidases (2020) (6)
- Comparison of transposon and deletion mutants in Mycobacterium tuberculosis: The case of rv1248c, encoding 2-hydroxy-3-oxoadipate synthase. (2015) (6)
- NHLBI Working Group: Progress and New Directions in Genetics of Tuberculosis (2005) (5)
- Cytostasis from nitrite a product of activated macrophages (1988) (5)
- Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB (2020) (5)
- Noncytotoxic Inhibition of the Immunoproteasome Regulates Human Immune Cells In Vitro and Suppresses Cutaneous Inflammation in the Mouse (2021) (5)
- A commentary: inducible nitric oxide synthase. (1991) (5)
- What can immunology contribute to the control of the world's leading cause of death from bacterial infection? (2015) (5)
- HYDROGEN PEROXIDE SECRETION BY MACROPHAGES AS A MARKER OF ACTIVATION AND A MEDIATOR OF CYTOLYSIS: ROLE OF TUMOR CELL ANTIOXIDANT DEFENSES (1982) (4)
- Hydrogen Peroxide Metabolism in Human (1981) (4)
- Regulation of macrophage functions by macrophage deactivating factor, a tumor cell-derived cytokine (1992) (4)
- Biological activities of a human pluripotent hemopoietic colony-stimulating factor. (1985) (4)
- A Multistress Model for High Throughput Screening Against Nonreplicating Mycobacterium tuberculosis. (2021) (4)
- Remembering Ralph Steinman (2011) (4)
- A time of change. (2017) (3)
- SECRETORY PRODUCTS IN CYTOTOXICITY (1983) (3)
- Perspective: Graduation time (2013) (3)
- Properties of resident and inflammatory macrophages in mouse liver (1985) (3)
- Rapid Interferon (cid:103) –dependent Clearance of Influenza A Virus and Protection from Consolidating Pneumonitis in Nitric Oxide Synthase 2–deficient Mice (1998) (3)
- CHAPTER 9 – Macrophage-Derived Nitric Oxide: Generation and Consequences (1992) (3)
- Structural insights into phosphopantetheinyl hydrolase PptH from Mycobacterium tuberculosis (2019) (3)
- Antibiotic proteins of human polymorphonuclear leukocytes ( bacteria / lysosomes / neutrophils ) (3)
- Advances in Brief A Novel Synthetic Oleanane Triterpenoid , 2-Cyano-3 , 12-dioxoolean-1 , 9-dien-28-oic Acid , with Potent Differentiating , Antiproliferative , and Anti-Inflammatory Activity 1 (1999) (2)
- Anti-inflammatory function of secretory leukocyte protease inhibitor (1999) (2)
- Physicochemical characteristics of several mediators from stimulated guinea pig and human lymphocytes. (1972) (2)
- Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease: (Journal of Neurochemistry (2009) 109 (502-512)) (2009) (2)
- Human studies at JEM: Immunology and beyond (2016) (2)
- Correction: Improved Control of Tuberculosis and Activation of Macrophages in Mice Lacking Protein Kinase R (2018) (2)
- In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas (2022) (2)
- Pulmonary Nodules in an Infliximab-Treated Rheumatoid Arthritis Patient (2007) (2)
- USE OF LIDOCAINE FOR DETACHMENT OF ADHERENT MONONUCLEAR PHAGOCYTES (1981) (2)
- Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors. (2022) (2)
- Abrupt Expression of TLR4 in TLR4-Deficient Macrophages Imposes a Selective Disadvantage: Genetic Evidence for TLR4-Dependent Responses to Endogenous, Nonmicrobial Stimuli1 (2006) (2)
- AGONIST AND ANTAGONIST EFFECTS OF INTERFERON a AND # ON ACTIVATION OF HUMAN MACROPHAGES Two Classes of Interferon y Receptors and Blockade ofthe (1988) (1)
- Phenotypic Tolerance and Bacterial Persistence (2018) (1)
- Participation of the cytoskeleton in macrophage responses to LPS (1992) (1)
- Glutathione depletion sensitizes tumor cells to peroxid- -mediated lysis by activated macrophages and granulocytes. Abstr. (1981) (1)
- JEM Advisory Editorial Board: Increasing diversity (2017) (1)
- A Journey in Science: Promise, Purpose, Privilege (2013) (1)
- Surmounting structural barriers to tackle endemic infectious diseases (2021) (1)
- Crystal Structure of Lipoamide Dehydrogenase from Mycobacterium tuberculosis (2005) (1)
- Artemisinin-based hybrids produce intracellular proteasome inhibitors that overcome resistance in Plasmodium falciparum (2021) (1)
- Immigration in science (2020) (1)
- Tuberculosis and the Tubercle Bacillus.Edited byStewart T Cole, Kathleen Davis Eisenach, David N McMurray, and, William R Jacobs, Jr.Washington (DC): ASM Press. $125.95. xii + 584 p + 13 pl; ill.; index. ISBN: 1–55581–295–3. 2005. (2005) (1)
- Generation of nitrogen oxides by murine macrophages: Replacement of low molecular weight factors in cytosol with reduced biopterins (1990) (1)
- human neutrophils to tumor necrosis factor (1996) (0)
- Properties of Transmembrane Channels Induced by Cytolytic Lymphocytes (2018) (0)
- Structural insights into phosphopantetheinyl hydrolase PptH from <fc><fi>Mycobacterium tuberculosis</fi></fc> (2020) (0)
- Treatment of Lepromatous Leprosy with Recombinant Interferon-Gamma (2020) (0)
- Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma (2019) (0)
- Transcriptional Biomarkers of Differentially Detectable Mycobacterium tuberculosis in Patient Sputum (2022) (0)
- Thymidine uptake by leukemia cells is stimulated by normal peritoneal cells and by mercaptoethanol but not by peritoneal cells from bcg- -infected mice. Abstr. (1975) (0)
- Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Citation (2016) (0)
- Introduction of Laurie H. Glimcher, MD. (2017) (0)
- Role of inducible nitric oxide synthase (iNOS) in endotoxin-induced leukocyte recruitment (1997) (0)
- United States Patent ( 19 ) Stuehr et al . ( 54 ) PURIFIED INDUCIBLE NITRICOXIDE SYNTHASE FLAVOPROTEIN (2017) (0)
- (lymphocytes/cell-mediated cytolysis/transmembrane channels/plan (2016) (0)
- Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2144 (2017) (0)
- Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II. (2023) (0)
- of the Macrophage Transcriptome in Response to Interferon- (cid:2) and Mycobacterium tuberculosis : Signaling Roles of Nitric Oxide Synthase-2 and Phagocyte Oxidase (2001) (0)
- Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes (2017) (0)
- Peripheral inflammatory response in human tuberculosis treatment is predicted by a combination of pathogen sterilization and microbiome dysbiosis (2020) (0)
- CHARACTERIZATION OF A LYMPHOCYTE FACTOR W H I C H ALTERS MACROPHAGE FUNCTIONS* BY CARL F. NATHAN, HEINZ G. REMOLD,~ AND JOHN R. DAVID (2003) (0)
- Cytokine Production in Response to Central SARM Is Required for Neuronal Injury and (2013) (0)
- Nitric Oxide and Inflammatory Response (2014) (0)
- Characterization of Phosphopantetheinyl Hydrolase from Mycobacterium tuberculosis (2021) (0)
- Acid Resistance in Mycobacterium tuberculosis (cid:1) (2009) (0)
- JEM Editorial Board: Expanding on the basis of cancer (2019) (0)
- Intestinal microbiome composition influences the peripheral inflammatory state during treatment of human tuberculosis (2020) (0)
- Synthesis of L-Arginine-Derived Nitrogen Oxides by Macrophage Cytosol: Partial Characterization of the Enzyme System (1990) (0)
- EB2001 symposium report Lung surfactant and reactive oxygen-nitrogen species: antimicrobial activity and host-pathogen interactions (2001) (0)
- Crystal Structure of Mycobacterial Tuberculosis Proteasome (2006) (0)
- MACROPHAGE OXYGEN-DEPENDENT ANTIMICROBIAL ACTIVITY Assay for 1-1202 Generation (2003) (0)
- PS-1 Chemical Biology of Non-replicating Mycobacterium tuberculosis (2009) (0)
- Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance (2023) (0)
- Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma (2019) (0)
- TLR4-Dependent Responses to Endogenous, Selective Disadvantage: Genetic Evidence for TLR4-Deficient Macrophages Imposes a Abrupt Expression of TLR4 in (2013) (0)
- Identification of Mycobacterium tuberculosis Counterimmune (cim) Mutants in Immunodeficient Mice by Differential Screening (2009) (0)
- Lung surfactant and reactive oxygen-nitrogen species (2001) (0)
- Secretory Leukocyte Protease Inhibitor, an Inhibitor of Neutrophil Activation, Is Elevated in Serum in Human Sepsis and Correlates With Severity of Organ Dysfunction: (1999) (0)
- Inhibition of Tumor Cell Ribonucleotide Reductase by Macrophage-derived Nitric Oxide By Nyoun (2003) (0)
- We are here for you and ready to hear from you (2020) (0)
- JEM goes viral (2020) (0)
- The Plague Prevention Service in Epidemics (1967) (0)
- [Antenatal diagnosis and fetal surgery]. (1984) (0)
- Nonmicrobial Stimuli TLR 4-Dependent Responses to Endogenous , Selective Disadvantage : Genetic Evidence for TLR 4-Deficient Macrophages Imposes a Abrupt Expression of TLR 4 in (2005) (0)
- Ethical Decisions: Stress and Distress in Medicine (2014) (0)
- A time of change (2017) (0)
- Antimicrobial proteins, compositions containing the same and their applications (1987) (0)
- Letter from Carl F. Nathan to Jean Pierre Poirier, Institut de Recherches Servier (France) (1979) (0)
- Lps-induced glucose utilization in c3h/hen and c3h/hej macrophages. Abstr. (1977) (0)
- Mitochondrial division/mitophagy inhibitor (Mdivi-1) protects right ventricle from severe failure (2012) (0)
- Behavioral deficits and progressive neuropathology in progranulin‐deficient mice: a mouse model of frontotemporal dementia (2010) (0)
- Title : Identification of a PptT Inhibitor that Kills M . tuberculosis and a Novel Mechanism of Resistance Author Block : (2017) (0)
- DEFICIENCY OF PHAGOCYTE OXIDASE CONFERS NO SURVIVAL BENEFIT IN A MOUSE MODEL OF SEPTIC SHOCK.: 80 (1998) (0)
- Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions (2021) (0)
- NHLBI Workshop Progress and New Directions in Genetics of Tuberculosis An NHLBI Working Group Report (2005) (0)
- ANTI-OX IDANT/ANTI-NITROSATIVE GENE FROM MYCOBACTERIUM TUBERCULOSIS: FUNCTIONAL CHARACTERIZATION IN E. COLI AND S. TYPHIMURIUM (1997) (0)
- E. coli expression of highly active recombinant murine interleukin-10 (1993) (0)
- The new face of JEM (2017) (0)
- JEM Advisory Editorial Board: Increasing diversity. (2017) (0)
- Structure of AhpD from Mycobacterium tuberculosis, a novel enzyme with thioredoxin-like activity. (2002) (0)
- Characterization of an NOS2 heterodimer comprised of an inactive and non-dimerizing mutant subunit (G450A) and a wild-type oxygenase domain subunit (1997) (0)
- The North Manchurian Plague Prevention Service, 1911-1931 (1967) (0)
- Acetyl Tripeptide Substrates N for and Mammalian Proteasomes tuberculosis Mycobacterium Distinct Specificities of Enzyme Catalysis and Regulation : (2008) (0)
- MACROPHAGES K ILL S YNGENEIC M ELANOMA C ELLS UNDER S TRICT A NAEROBIC C ONDITIONS (1984) (0)
- Correction to "Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis". (2019) (0)
- Contest between host and pathogen over reactive nitrogen intermediates (RNI) (2003) (0)
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