Carlos Cruchaga
#158,977
Most Influential Person Now
Researcher
Carlos Cruchaga's AcademicInfluence.com Rankings
Carlos Cruchagaengineering Degrees
Engineering
#7735
World Rank
#9149
Historical Rank
Biomedical Engineering
#783
World Rank
#795
Historical Rank
Carlos Cruchagabiology Degrees
Biology
#13045
World Rank
#16568
Historical Rank
Genetics
#1568
World Rank
#1673
Historical Rank
Neuroscience
#2448
World Rank
#2513
Historical Rank
Download Badge
Engineering Biology
Why Is Carlos Cruchaga Influential?
(Suggest an Edit or Addition)According to Wikipedia, Carlos Cruchaga is a human genomicist with expertise in multi-omics, informatics, and neurodegeneration, with a focus on Alzheimer's and Parkinson's Disease. He is a Professor of Psychiatry, Neurology and Genetics and Washington University School of Medicine. He is founding director of the Neurogenomics and Informatic center at Washington University School of Medicine.
Carlos Cruchaga's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease (2013) (3484)
- TREM2 variants in Alzheimer's disease. (2013) (2173)
- Common variants in ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer’s disease (2011) (1701)
- Common variants in MS4A4/MS4A6E, CD2uAP, CD33, and EPHA1 are associated with late-onset Alzheimer’s disease (2011) (1656)
- Letter abstract - Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's Disease (2009) (1644)
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease, and shows evidence for additional susceptibility genes (2009) (1441)
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (2013) (1388)
- Analysis of shared heritability in common disorders of the brain (2016) (1385)
- Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease (2014) (1230)
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (1073)
- Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance (2011) (997)
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease (2017) (693)
- ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy (2017) (676)
- Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease (2010) (587)
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2018) (578)
- Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease (2019) (487)
- Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease (2013) (418)
- Alzheimer’s Disease Genetics: From the Bench to the Clinic (2014) (383)
- GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease (2013) (332)
- Common polygenic variation enhances risk prediction for Alzheimer's disease. (2015) (316)
- Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis (2012) (308)
- A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease (2017) (288)
- Common variants at MS 4 A 4 / MS 4 A 6 E , CD 2 AP , CD 33 and EPHA 1 are associated with late-onset Alzheimer ’ s disease (2011) (274)
- Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families (2012) (270)
- Expression of Novel Alzheimer’s Disease Risk Genes in Control and Alzheimer’s Disease Brains (2012) (266)
- Frontotemporal dementia and its subtypes: a genome-wide association study (2014) (262)
- Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status (2016) (252)
- A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease (2020) (252)
- A NOVEL ALZHEIMER DISEASE LOCUS LOCATED NEAR THE GENE ENCODING TAU PROTEIN (2015) (246)
- Coding variants in TREM2 increase risk for Alzheimer's disease. (2014) (245)
- Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers II: Sigma-2/PGRMC1 Receptors Mediate Abeta 42 Oligomer Binding and Synaptotoxicity (2014) (239)
- Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence (2009) (230)
- TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis. (2014) (225)
- Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. (2009) (205)
- Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study (2019) (194)
- Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease. (2012) (187)
- An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations (2019) (182)
- Assessment of Racial Disparities in Biomarkers for Alzheimer Disease (2019) (173)
- Convergent genetic and expression data implicate immunity in Alzheimer's disease (2014) (172)
- TREM2 is associated with the risk of Alzheimer's disease in Spanish population (2013) (171)
- Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation (2018) (171)
- Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels. (2011) (154)
- Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer’s disease (2019) (150)
- Transethnic genome-wide scan identifies novel Alzheimer's disease loci (2017) (149)
- Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology (2019) (141)
- Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. (2014) (140)
- TARDBP 3′-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy (2009) (135)
- Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms (2016) (134)
- The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk (2019) (131)
- SNPs Associated with Cerebrospinal Fluid Phospho-Tau Levels Influence Rate of Decline in Alzheimer's Disease (2010) (128)
- Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease. (2016) (118)
- TREM2 Variants in Alz hei mer's Disease (2012) (118)
- Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers (2017) (117)
- TREM2 is associated with increased risk for Alzheimer’s disease in African Americans (2015) (116)
- Missense variant in TREML2 protects against Alzheimer's disease (2014) (115)
- Genome-Wide Association Study of CSF Levels of 59 Alzheimer's Disease Candidate Proteins: Significant Associations with Proteins Involved in Amyloid Processing and Inflammation (2014) (114)
- A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death (2014) (114)
- A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease (2021) (113)
- Association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer disease. (2011) (113)
- TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis (2020) (111)
- A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain (2019) (106)
- C9orf72 hexanucleotide repeat expansions in clinical Alzheimer disease. (2013) (105)
- Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy (2021) (103)
- Exome-Sequencing Confirms DNAJC5 Mutations as Cause of Adult Neuronal Ceroid-Lipofuscinosis (2011) (103)
- Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American cohort (2012) (102)
- Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis. (2014) (98)
- The epigenetic landscape of Alzheimer's disease (2014) (98)
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes (2018) (98)
- Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition (2008) (94)
- Variants in GBA, SNCA, and MAPT influence Parkinson disease risk, age at onset, and progression (2016) (92)
- A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease (2016) (92)
- Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms (2018) (89)
- Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study (2018) (83)
- Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. (2018) (81)
- APOE genotype regulates pathology and disease progression in synucleinopathy (2020) (78)
- Lack of C9ORF72 coding mutations supports a gain of function for repeat expansions in amyotrophic lateral sclerosis (2013) (77)
- Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease (2011) (75)
- Pathogenic cysteine mutations affect progranulin function and production of mature granulins (2010) (74)
- Longitudinal brain imaging in preclinical Alzheimer disease: impact of APOE &egr;4 genotype (2018) (71)
- Phosphorylated Tau-Aβ42 Ratio as a Continuous Trait for Biomarker Discovery for Early-Stage Alzheimer’s Disease in Multiplex Immunoassay Panels of Cerebrospinal Fluid (2014) (71)
- TYROBP genetic variants in early-onset Alzheimer's disease (2016) (67)
- Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (2009) (64)
- Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD (2019) (63)
- The PSEN1, p.E318G Variant Increases the Risk of Alzheimer's Disease in APOE-ε4 Carriers (2013) (62)
- Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience (2017) (61)
- The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. (2012) (61)
- Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease (2019) (61)
- Rs5848 variant influences GRN mRNA levels in brain and peripheral mononuclear cells in patients with Alzheimer's disease. (2009) (59)
- Genetic variants and functional pathways associated with resilience to Alzheimer’s disease (2020) (59)
- BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease. (2016) (59)
- CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline (2018) (59)
- A missense variant in SLC39A8 is associated with severe idiopathic scoliosis (2018) (58)
- Characterizing the Role of Brain Derived Neurotrophic Factor Genetic Variation in Alzheimer’s Disease Neurodegeneration (2013) (58)
- Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson’s Disease (2016) (58)
- A polygenic burden of rare variants across extracellular matrix genes among individuals with adolescent idiopathic scoliosis. (2016) (56)
- Shared genetic contribution to ischemic stroke and Alzheimer's disease (2016) (55)
- Palmitoylation-induced Aggregation of Cysteine-string Protein Mutants That Cause Neuronal Ceroid Lipofuscinosis* (2012) (55)
- Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism (2016) (55)
- Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer’s disease pathogenesis (2020) (53)
- Cortical atrophy and language network reorganization associated with a novel progranulin mutation. (2009) (53)
- Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation (2020) (52)
- Polygenic risk scores in familial Alzheimer disease (2017) (52)
- TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers (2019) (51)
- Sex differences in the genetic predictors of Alzheimer's pathology. (2019) (51)
- Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease (2009) (51)
- TREM2 and neurodegenerative disease. (2013) (50)
- Validating predicted biological effects of Alzheimer's disease associated SNPs using CSF biomarker levels. (2010) (49)
- Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels (2017) (49)
- Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure (2018) (47)
- The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease. (2016) (46)
- Parkinson disease is not associated with C9ORF72 repeat expansions (2013) (45)
- A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin (2016) (45)
- Age-at-Onset in Late Onset Alzheimer Disease is Modified by Multiple Genetic Loci (2014) (44)
- Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP (2018) (43)
- The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion (2019) (42)
- Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline. (2018) (41)
- Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders (2021) (41)
- Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease. (2021) (41)
- SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. (2014) (41)
- Frontobasal gray matter loss is associated with the TREM2 p.R47H variant (2014) (40)
- Sex-specific genetic predictors of Alzheimer’s disease biomarkers (2018) (40)
- Rarity of the Alzheimer disease-protective APP A673T variant in the United States. (2015) (39)
- PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome: A Genome-Wide Meta-Analysis (2019) (39)
- ABCA7 p.G215S as potential protective factor for Alzheimer's disease (2016) (38)
- Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing (2018) (36)
- Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging (2018) (35)
- Caspase-8, association with Alzheimer’s Disease and functional analysis of rare variants (2017) (34)
- Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase Inhibit Phosphorolysis and Resensitize the 3′-Azido-3′-deoxythymidine (AZT)-resistant Polymerase to AZT-5′-triphosphate* (2003) (34)
- Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network (2019) (33)
- Different MAPT haplotypes are associated with Parkinson's disease and progressive supranuclear palsy (2011) (33)
- A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains. (2017) (33)
- Alzheimer's disease: rare variants with large effect sizes. (2015) (33)
- Variants in PPP3R1 and MAPT are associated with more rapid functional decline in Alzheimer's disease: The Cache County Dementia Progression Study (2014) (33)
- Identification of rare variants in Alzheimer’s disease (2014) (33)
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3 (2018) (31)
- Whole genome sequencing of Caribbean Hispanic families with late‐onset Alzheimer's disease (2018) (31)
- A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers (2018) (30)
- 5′-upstream variants of CRHR1 and MAPT genes associated with age at onset in progressive supranuclear palsy and cortical basal degeneration (2009) (29)
- The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease (2015) (29)
- Socioeconomic Status Mediates Racial Differences Seen Using the AT(N) Framework (2020) (29)
- Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS (2017) (29)
- Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study (2022) (29)
- Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits (2016) (28)
- Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease (2017) (28)
- Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer’s Disease (2016) (27)
- Triggering receptor expressed on myeloid cells 2 (TREM2): a potential therapeutic target for Alzheimer disease? (2018) (26)
- A rare mutation in UNC 5 C predisposes to late-onset Alzheimer ’ s disease and increases neuronal cell death (2014) (26)
- Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European–Americans (2015) (26)
- Stroke genetics informs drug discovery and risk prediction across ancestries (2022) (26)
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2018) (26)
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2018) (26)
- Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (26)
- OASIS-3: LONGITUDINAL NEUROIMAGING, CLINICAL, AND COGNITIVE DATASET FOR NORMAL AGING AND ALZHEIMER’S DISEASE (2018) (26)
- Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (2018) (25)
- Inhibition of phosphorolysis catalyzed by HIV-1 reverse transcriptase is responsible for the synergy found in combinations of 3'-azido-3'-deoxythymidine with nonnucleoside inhibitors. (2005) (25)
- Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer’s Disease Sequencing Project (2018) (25)
- Discovery and validation of autosomal dominant Alzheimer’s disease mutations (2018) (25)
- Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease (2021) (25)
- TMEM106B: a strong FTLD disease modifier (2014) (24)
- Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease (2018) (24)
- Genetic variation of the retromer subunits VPS26A/B-VPS29 in Parkinson's disease (2014) (23)
- Rare variants in FBN 1 and FBN 2 are associated with severe adolescent idiopathic scoliosis (2014) (23)
- TREM 2 is associated with increased risk for Alzheimer ' s disease in African Americans (23)
- Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid (2022) (22)
- Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer's disease (2019) (22)
- Sequence of Alzheimer disease biomarker changes in cognitively normal adults (2020) (22)
- Prospective natural history study of C9orf72 ALS clinical characteristics and biomarkers (2019) (22)
- Effect of BDNFVal66Met on disease markers in dominantly inherited Alzheimer's disease (2018) (21)
- Clinical Variables and Genetic Risk Factors Associated with the Acute Outcome of Ischemic Stroke: A Systematic Review (2019) (21)
- Identification of plexin A4 as a novel clusterin receptor links two Alzheimer’s disease risk genes (2016) (21)
- Early Neurological Change After Ischemic Stroke Is Associated With 90-Day Outcome (2020) (21)
- A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease (2018) (20)
- Alzheimer's disease alters oligodendrocytic glycolytic and ketolytic gene expression (2021) (19)
- African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants (2021) (18)
- Selective Excision of Chain-terminating Nucleotides by HIV-1 Reverse Transcriptase with Phosphonoformate as Substrate* (2006) (18)
- SORL1 variants across Alzheimer’s disease European American cohorts (2016) (18)
- Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease (2020) (18)
- Pleiotropic Effects of Variants in Dementia Genes in Parkinson Disease (2018) (18)
- Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network (2018) (18)
- Overlapping genetic architecture between Parkinson disease and melanoma (2019) (17)
- Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study (2022) (17)
- Biphasic cortical macro‐ and microstructural changes in autosomal dominant Alzheimer's disease (2020) (17)
- CCL23: A Chemokine Associated with Progression from Mild Cognitive Impairment to Alzheimer's Disease. (2020) (17)
- Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke (2020) (17)
- Genome‐wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways (2020) (16)
- The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease (2013) (16)
- Missense variant in TREML 2 protects against Alzheimer ’ s Disease (2013) (15)
- Correction: Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families (2012) (15)
- Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease (2018) (15)
- Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss (2015) (15)
- Overlap in the Genetic Architecture of Stroke Risk, Early Neurological Changes, and Cardiovascular Risk Factors. (2019) (14)
- Neuronal VCP loss of function recapitulates FTLD-TDP pathology (2021) (14)
- Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels (2018) (13)
- Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40 (2016) (13)
- Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes. (2020) (12)
- Genetic high throughput screening in Retinitis Pigmentosa based on high resolution melting (HRM) analysis. (2013) (12)
- Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome‐wide association study in over 12,000 non‐demented participants (2021) (12)
- Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2019) (12)
- TREM 2 brain transcript-specific studies in AD and TREM 2 mutation carriers (2019) (12)
- Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease (2022) (12)
- Sharper in the morning: Cognitive time of day effects revealed with high-frequency smartphone testing (2021) (12)
- Higher Body Mass Index Is Associated with Lower Cortical Amyloid-β Burden in Cognitively Normal Individuals in Late-Life. (2019) (12)
- Cell specific peripheral immune responses predict survival in critical COVID-19 patients (2022) (12)
- The MS4A gene cluster is a key regulator of soluble TREM2 and Alzheimer disease risk (2018) (11)
- Modeling autosomal dominant Alzheimer's disease with machine learning (2021) (11)
- An APOE-independent cis-eSNP on chromosome 19q13.32 influences tau levels and late-onset Alzheimer's disease risk (2018) (11)
- Rare and de novo coding variants in chromodomain genes in Chiari I malformation. (2020) (11)
- Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease (2018) (11)
- Autosomal dominantly inherited alzheimer disease: Analysis of genetic subgroups by machine learning (2020) (11)
- The Dystonia Coalition: A Multicenter Network for Clinical and Translational Studies (2021) (11)
- Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease (2021) (10)
- SUCLG 2 identified as both a determinator of CSF A b 1 – 42 levels and an attenuator of cognitive decline in Alzheimer ’ s disease (2014) (10)
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (vol 41, pg 1088, 2009) (2013) (10)
- Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers (2022) (10)
- Phenotypic Similarities Between Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease: A Single-Family Case-Control Study. (2016) (10)
- Genomic and multi-tissue proteomic integration for understanding the biology of disease and other complex traits (2020) (10)
- Validation of a clinical-genetics score to predict hemorrhagic transformations after rtPA (2019) (9)
- Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease (2022) (9)
- Association of Acquired and Heritable Factors With Intergenerational Differences in Age at Symptomatic Onset of Alzheimer Disease Between Offspring and Parents With Dementia (2019) (9)
- Genetic Discoveries in AD Using CSF Amyloid and Tau (2014) (9)
- Exome-wide rare variant analysis in familial essential tremor. (2020) (9)
- Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke (2022) (9)
- Remote cognitive assessment approaches in the Dominantly Inherited Alzheimer Network (DIAN) (2020) (9)
- Biobank-wide association scan identifies risk factors for late-onset Alzheimer’s disease and endophenotypes (2018) (9)
- A common haplotype lowers SPI1 (PU.1) expression in myeloid cells and delays age at onset for Alzheimer’s disease (2017) (9)
- Physical Exercise and Longitudinal Trajectories in Alzheimer Disease Biomarkers and Cognitive Functioning (2020) (9)
- Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer’s disease (2020) (8)
- Novel progranulin variants do not disrupt progranulin secretion and cleavage (2013) (8)
- Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease (2021) (8)
- PHENOTYPIC SIMILARITIES BETWEEN LATE-ONSET AUTOSOMAL DOMINANT AND SPORADIC ALZHEIMER DISEASE: A SINGLE-FAMILY CASE-CONTROL STUDY (2016) (8)
- Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke. (2022) (8)
- Relationships between big‐five personality factors and Alzheimer's disease pathology in autosomal dominant Alzheimer's disease (2020) (8)
- Gene Expression Imputation Across Multiple Tissue Types Provides Insight Into the Genetic Architecture of Frontotemporal Dementia and Its Clinical Subtypes (2021) (8)
- as potential protective factor for Alzheimer’s disease (2016) (7)
- Paving the road for the study of epigenetics in neurodegenerative diseases (2016) (7)
- MULTI-ANCESTRY GENETIC STUDY IN 5,876 PATIENTS IDENTIFIES AN ASSOCIATION BETWEEN EXCITOTOXIC GENES AND EARLY OUTCOMES AFTER ACUTE ISCHEMIC STROKE. (2020) (7)
- Causal Effect of MMP-1 (Matrix Metalloproteinase-1), MMP-8, and MMP-12 Levels on Ischemic Stroke (2021) (7)
- A landscape of the genetic and cellular heterogeneity in Alzheimer disease (2021) (7)
- 122nd annual meeting american neurological association (1997) (7)
- CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN (2017) (7)
- Validating predicted biological effects of Alzheimer's disease associated SNPs using cerebrospinal fluid biomarker levels (2010) (7)
- Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN) (2020) (7)
- Precision genome-editing with CRISPR/Cas9 in human induced pluripotent stem cells (2017) (6)
- Association of BDNF Val66Met With Tau Hyperphosphorylation and Cognition in Dominantly Inherited Alzheimer Disease. (2022) (6)
- Nonnucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3’-azido-3’-deoxythymidine (AZT)-resistant polymerase to AZTTP (6)
- Pooled-DNA target sequencing of Parkinson genes reveals novel phenotypic associations in Spanish population (2018) (6)
- Comparative Analysis of Alzheimer's Disease Cerebrospinal Fluid Biomarkers Measurement by Multiplex SOMAscan Platform and Immunoassay-Based Approach. (2022) (6)
- TMEM230 in Parkinson's disease (2017) (6)
- Advances in Genetic and Molecular Understanding of Alzheimer’s Disease (2021) (6)
- Autosomal dominant and sporadic late onset Alzheimer disease share a common in vivo pathophysiology. (2022) (6)
- Whole exome sequencing analysis reveals TRPV3 as a risk factor for cardioembolic stroke/subtitle (2016) (6)
- Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25 (2020) (6)
- Baseline Microglial Activation Correlates With Brain Amyloidosis and Longitudinal Cognitive Decline in Alzheimer Disease (2022) (6)
- Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience (2017) (6)
- Network dysfunction in cognitively normal APOE ε4 carriers is related to subclinical tau (2021) (5)
- Single nucleotide variations in ZBTB46 are associated with post-thrombolytic parenchymal haematoma. (2021) (5)
- Pooled-DNA Sequencing for Elucidating New Genomic Risk Factors, Rare Variants Underlying Alzheimer's Disease. (2016) (5)
- Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease (2022) (5)
- Cruchaga & Goate reply (2015) (5)
- Genome-Wide Association Study of White Blood Cell Counts in Patients With Ischemic Stroke. (2019) (5)
- Synchronized genetic activities in Alzheimer’s brains revealed by heterogeneity-capturing network analysis (2020) (5)
- A Multi‐center Genome‐wide Association Study of Cervical Dystonia (2021) (5)
- Correction to: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience (2018) (5)
- Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease (2022) (5)
- Genetic highthroughput screening in retinitis pigmentosa based on high resolution melting (HRM) analysis. (2013) (5)
- COMPARING SMARTPHONE-ADMINISTERED COGNITIVE ASSESSMENTS WITH CONVENTIONAL TESTS AND BIOMARKERS IN SPORADIC AND DOMINANTLY INHERITED ALZHEIMER DISEASE (2018) (5)
- A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain (2019) (5)
- Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer’s disease (2020) (4)
- Gantenerumab in‐depth outcomes: Results of the DIAN‐TU prevention trial of solanezumab and gantenerumab in dominantly inherited AD (2020) (4)
- RP11-362K2.2:RP11-767I20.1 Genetic Variation Is Associated with Post-Reperfusion Therapy Parenchymal Hematoma. A GWAS Meta-Analysis (2021) (4)
- SNPs in catalytic and regulatory subunits of calcineurin are associated with CSF tau levels and mRNA levels (2009) (4)
- Overview of dominantly inherited AD and top‐line DIAN‐TU results of solanezumab and gantenerumab (2020) (4)
- Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer disease brains (2021) (4)
- C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts (2020) (4)
- Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease (2020) (4)
- TMEM 106 B gene polymorphism is associated with age at onset in granulin mutation carriers and plasma granulin protein levels (2011) (4)
- A COMMON ALLELE IN SPI1 LOWERS RISK AND DELAYS AGE AT ONSET FOR ALZHEIMER'S DISEASE (2016) (4)
- Cruchaga & Goate reply (2015) (4)
- Long runs of homozygosity are associated with Alzheimer’s disease (2021) (4)
- Preclinical Alzheimer's disease biomarkers accurately predict cognitive and neuropathological outcomes. (2022) (3)
- Functional brain age prediction suggests accelerated aging in preclinical familial Alzheimer’s disease, irrespective of fibrillar amyloid-beta pathology (2020) (3)
- Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network (2018) (3)
- Association and expression analyses with SNPs in TOMM40 in Alzheimer's disease (2011) (3)
- THE MS4A GENE CLUSTER IS A KEY MODULATOR OF SOLUBLE TREM2 AND ALZHEIMER DISEASE RISK (2019) (3)
- Ptau-Aβ42 ratio as a continuous trait for biomarker discovery for early stage Alzheimer’s disease in multiplex immunoassay panels of Cerebrospinal fluid (2014) (3)
- Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains (2022) (3)
- Common polygenic variation can predict risk of Alzheimer ’ s disease (2016) (3)
- Single- nuclei RNA sequencing from human brain to study for Mendelian and sporadic AD (2019) (3)
- A rare coding variant alters UNC5C function and predisposes to Alzheimer's disease (2013) (3)
- Deep resequencing of GWAS loci associated with Alzheimer's disease (2012) (3)
- Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke (2022) (3)
- Rare and de novo coding variants in chromodomain genes in Chiari I malformation. (2021) (3)
- Chronic neuropsychiatric sequelae of SARS‐CoV‐2: Protocol and methods from the Alzheimer's Association Global Consortium (2022) (3)
- Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis (2020) (3)
- Neuroimaging within the Dominantly Inherited Alzheimer’s Network (DIAN): PET and MRI (2022) (3)
- Association of genetic variants with cerebrospinal fluid protein levels of ACE, MMP3 and other proteins and risk for Alzheimer's disease (2013) (2)
- Correction: Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease (2011) (2)
- Gantenerumab in‐depth outcomes (2020) (2)
- Large-scale proteome analysis of CSF implicates altered glucose metabolism in Alzheimer's disease (2021) (2)
- Exome sequencing identifies rare damaging variants in the ATB8B4 and ABCA1 genes as novel risk factors for Alzheimer’s disease (2021) (2)
- Sharper in the morning: Cognitive sundowning revealed with high‐frequency smartphone testing (2021) (2)
- Undetected Neurodegenerative Disease Biases Estimates of Cognitive Change in Older Adults (2021) (2)
- Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan. (2022) (2)
- Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study (2023) (2)
- Proteinopathy and Longitudinal Cognitive Decline in Parkinson Disease (2022) (2)
- Multi-tissue proteomics identifies molecular signatures for sporadic and genetically defined Alzheimer disease cases (2021) (2)
- Is the Arg5His MAPT variant pathogenic for dementia and motor neuron disease? (2011) (2)
- An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations (2019) (2)
- Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study (2022) (2)
- Rare and de novo coding variants in chromodomain genes in Chiari I malformation. (2021) (2)
- The TMEM106B rs1990621 protective variant is also associated with increased neuronal proportion (2019) (2)
- An atlas of cortical circular RNA expression demonstrates clinical and pathological 1 associations with Alzheimer disease 2 3 (2019) (2)
- A new strategy to inhibit the excision reaction catalysed by HIV-1 reverse transcriptase: compounds that compete with the template-primer. (2007) (2)
- A Polygenic Risk Score Based on a Cardioembolic Stroke Multitrait Analysis Improves a Clinical Prediction Model for This Stroke Subtype (2022) (2)
- Protracted course progressive supranuclear palsy (2022) (2)
- Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk (2021) (2)
- Author Correction: Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS (2018) (2)
- Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer and coronary disease pathways (2022) (2)
- Weakly activated core inflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer’s disease (2021) (2)
- Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer’s disease in the European American population (2021) (2)
- Correction: Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation (2019) (2)
- Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure (2018) (2)
- Transferability of Alzheimer Disease Polygenic Risk Score Across Populations and Its Association With Alzheimer Disease-Related Phenotypes (2022) (1)
- A comparison of the Montreal Cognitive Assessment and standard cognitive measures in the National Alzheimer’s Coordinating Center and Knight Alzheimer’s Disease Research Center cohorts (2020) (1)
- Solanezumab in‐depth outcomes (2020) (1)
- GWAS for CSF TREM2 levels identify new variants implicated on TREM2 biology and Alzheimer disease (2022) (1)
- Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes (2022) (1)
- CELL-TYPE PROFILING TO IDENTIFY THE TRANSCRIPTOMIC DOWNSTREAM EVENTS TRIGGERED BY EARLY-ONSET AUTOSOMAL DOMINANT AD MUTATIONS (2017) (1)
- Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Aβ-PET, neurodegeneration, and cognition. (2022) (1)
- CEREBROSPINAL FLUID LEVELS OF AMYLOID BETA AND TAU AS ENDOPHENOTYPES REVEAL NOVEL VARIANTS POTENTIALLY INFORMATIVE FOR ALZHEIMER'S DISEASE (2016) (1)
- Discovery and validation of dominantly inherited Alzheimer’s disease mutations in populations from Latin America (2022) (1)
- Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries (2022) (1)
- Genome-wide Association Study Links APOEɛ4 and BACE1 Variants with Plasma Amyloid β Levels (2017) (1)
- Support for Genetic Association Between Variants in PPP3R1 and MAPT and Rate of Progression of Alzheimer’s Disease (2011) (1)
- Rare variants in APP and PSEN1 genes associated with extreme levels of beta-amyloid 42 and tau protein in cerebrospinal fluid (2013) (1)
- Exome-sequencing in a large dataset of late-onset families with Alzheimer’s disease (2015) (1)
- ABCA7 and MS4A6A expression are upregulated in Alzheimer's disease brains (2012) (1)
- Protective genetic variants in the MS4A gene cluster modulate microglial activity (2020) (1)
- Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease (2021) (1)
- Quantitative endophenotypes as an alternative approach to understanding genetic risk in neurodegenerative diseases (2021) (1)
- Lack of C 9 ORF 72 coding mutations supports a gain of function for repeat expansions in ALS (2013) (1)
- MULTITRAIT ANALYSIS EXPANDS GENETIC RISK FACTORS IN CARDIOEMBOLIC STROKE (2021) (1)
- A failure of forward translation? The case of neuroprotection (2021) (1)
- Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease (2022) (1)
- Immune-related genetic enrichment in frontotemporal dementia (2017) (1)
- CSF polygenic risk AD biomarkers predict brain amyloid and free recall (2021) (1)
- TREM2 is associated with increased risk for Alzheimer’s disease in African Americans (2015) (1)
- Brain network decoupling with increased serum neurofilament and reduced cognitive function in Alzheimer's disease. (2023) (1)
- EXOME ARRAY ANALYSIS IDENTIFIES NOVEL RISK VARIANTS FOR ALZHEIMER'S DISEASE WITH ONSET BEFORE 65 YEARS (2014) (1)
- CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer disease (2022) (1)
- Defining the role of PLD3 in Alzheimer’s disease pathology (2021) (1)
- The National Institute on Aging Late‐Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery (2022) (1)
- Severe acute neurotoxicity reflects absolute intra-carotid 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine dose in non-human primates (2021) (1)
- Polygenic Risk Score of Sporadic late Onset Alzheimer Disease Reveals a Shared Architecture with the Familial and Early Onset Forms (2017) (1)
- WHOLE EXOME SEQUENCING ANALYSIS IN EARLY ONSET ALZHEIMER REVEALS NOVEL CANDIDATE GENES (2019) (1)
- Proteomic clusters underlie heterogeneity in preclinical Alzheimer's disease progression. (2022) (1)
- Alzheimer's Disease Alters Oligodendrocytic Glycolytic and Ketolytic Gene Expression (2021) (1)
- Novel CYP1B1-RMDN2 Alzheimers disease locus identified by genome-wide association analysis of cerebral tau deposition on PET (2023) (1)
- The TREM2 Variant p.R47H is a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis (I5-2.002) (2014) (1)
- Weakly activated core neuroinflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer’s disease (2022) (1)
- BDNF VAL66MET MODERATES COGNITIVE IMPAIRMENT, NEURONAL DYSFUNCTION AND TAU IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE (2016) (1)
- Exome array analysis identifies novel risk variants for non-familial early-onset Alzheimer’s disease (2013) (1)
- Genetic and glial heterogeneity in Alzheimer disease (2022) (0)
- Two Novel PDE11A Genetic Variants Increase Tau Phosphorylations in Early-onset Alzheimer's Disease (2020) (0)
- Functional exploration of AGFG2, a novel player in the pathology of Alzheimer disease (2021) (0)
- Alzheimer’s disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals (2023) (0)
- Single nuclei RNA‐sequencing of GWAS loci variant carriers elucidates cell‐types and transcriptional profile alterations associated with Alzheimer disease (2021) (0)
- AD‐causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains. (2022) (0)
- Replication study of AD‐associated rare variants (2022) (0)
- Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains (2022) (0)
- Multi‐omics approaches reveal a link between the MS4A gene loci, TREM2, and microglia function (2021) (0)
- Axonal damage and astrocytosis are biological correlates of grey matter network integrity loss: a cohort study in autosomal dominant Alzheimer disease (2023) (0)
- APOE ε4 genotype, amyloid-β, and sex interact to predict tau in regions of high APOE mRNA expression (2022) (0)
- Phospholipase D3 contributes to Alzheimer's disease risk via disruption of Aβ clearance and microglia response to amyloid plaques (2022) (0)
- The interaction of APOE genotype and amyloid‐β PET predicts PET but not CSF measures of tauopathy in regions of high APOE mRNA expression (2021) (0)
- Characterizing Disrupted Cellular Crosstalk Signaling Networks in Alzheimer’s Disease Using Single‐Nuclei Transcriptomics (2022) (0)
- Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease (2019) (0)
- Defining the role of PLD3 in Alzheimer disease pathology (2021) (0)
- Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease (2023) (0)
- P430: Application of ACMG/AMP variant classification guidelines to Alzheimer’s disease-associated genetic variation (2023) (0)
- Genome‐wide scan of Alzheimer disease cohort identifies genetic loci associated with human brain metabolite levels (2021) (0)
- Post-GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease implicates mediation through GPX3 (2022) (0)
- Progressive white matter injury in autosomal dominant Alzheimer’s disease is strongly associated with cerebral microbleeds and neurodegeneration (2022) (0)
- Longitudinal cascades of Alzheimer disease biomarkers across the entire adult lifespan among cognitively normal adults (2021) (0)
- 400. An Alzheimer’s Disease-Associated circRNA Regulates Long App and MAPT mRNA Isoform Expression (2023) (0)
- Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss (2015) (0)
- A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease (2020) (0)
- Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer’s and coronary disease pathways (2023) (0)
- Differential impact of APOE genetic variants on autosomal dominant‐ and sporadic‐ Alzheimer disease (2022) (0)
- Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease (2018) (0)
- Profiling the metabolic landscape of AD (2021) (0)
- PS1 mutation position influences regional PiB‐uptake and white matter lesion volume (2021) (0)
- Prediction of Alzheimer disease using plasma RNA sequences from dementia genes (2021) (0)
- Comparison of amyloid accumulation between Down syndrome and autosomal‐dominant Alzheimer disease (2022) (0)
- AD‐causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains (2022) (0)
- Impact of MAPT mutations on transcriptomic signatures of FTLD brains and patient‐derived pluripotent cell models (2021) (0)
- Longitudinal cerebrospinal fluid phosphorylated tau181 and total tau do not reflect tau PET retention in dominantly inherited Alzheimer disease (2022) (0)
- Discovery and validation of dominantly inherited Alzheimer’s disease mutations in populations from Latin America (2022) (0)
- Biomarker clustering in autosomal dominant Alzheimer's disease (2022) (0)
- A large‐scale genome‐wide association study of early‐onset Alzheimer disease (2022) (0)
- Using amyloid PET as a biomarker to detect progression of early Alzheimer’s disease (2021) (0)
- A flexible modeling approach for biomarker‐based computation of absolute risk of Alzheimer's disease dementia (2022) (0)
- Multi‐omics data integration reveals clinically meaningful molecular profiles of Alzheimer disease (2021) (0)
- Comparison of amyloid accumulation between Down syndrome and autosomal‐dominant Alzheimer disease (2022) (0)
- Loss of estrogen unleashing neuro-inflammation increases the risk of Alzheimer’s disease in women (2022) (0)
- TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers (2019) (0)
- Pleiotropic effect of LRRK2 on Parkinson‐associated proteins and processing of pathological alpha‐synuclein in myeloid cells (2022) (0)
- Development of an App-Based Patient-Centered Outcome (PCO) Measure for Dystonia (2022) (0)
- P3-214: Cerebrospinal fluid tau levels, an endophenotype for genetic studies of Alzheimer's disease (2008) (0)
- HIGH-THROUGHPUT OMICS EXPLORER FOR ALZHEIMER'S DISEASE AND COMPLEX TRAITS GENETIC ANALYSIS (2019) (0)
- Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2019) (0)
- Stem cell models of primary tauopathies reveal defects in synaptic function (2021) (0)
- Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2019) (0)
- A common haplotype lowers SPI1 expression in myeloid cells and delays age at onset for Alzheimer’s disease of Alzheimer's Alzheimer's Disease Neuroimaging Initiative (2022) (0)
- Proceedings of the 26th International Stroke Genetics Consortium Workshop: St. Louis, MO (2019) (0)
- Genome-Wide Association Analyses Using Cerebrospinal Fluid Tau and Phospho-Tau Levels As An Endophenotype for Alzheimer’s Disease (2011) (0)
- ALZHEIMER'S DISEASE RISK VARIANTS IN PHOSPHOLIPASE D3 ALTER APP METABOLISM BY GAMMA-DEPENDENT AND GAMMA-INDEPENDENT MECHANISMS (2014) (0)
- The clinical phenotype of late-onset autosomal dominant Alzheimer disease due to a PSEN1 mutation resembles sporadic Alzheimer disease: A single-family case-control study (P2.237) (2016) (0)
- Erratum: Author Correction: Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS (Scientific reports (2017) 7 1 (8899)) (2018) (0)
- IDENTIFICATION OF DIFFERENTIALLY EXPRESSED GENES AND POTENTIALLY NOVEL DRUGS FOR FRONTOTEMPORAL LOBAR DEMENTIA WITH TAU INCLUSIONS BY A DEPENDABLE ANALYSIS APPROACH (2018) (0)
- Correction to: Overlapping genetic architecture between Parkinson disease and melanoma (2020) (0)
- AN E-QTL META-ANALYSIS OF BRAIN CORTICAL TISSUE ACROSS FIVE CONSORTIUM-BASED STUDIES (2019) (0)
- Association study of recently reported AD risk variants with cerebrospinal fluid AD biomarker levels (2011) (0)
- Systematic validation of variants of unknown significance in PSEN1 (2021) (0)
- EXAMINING THE INFLUENCE OF UNDETECTED ATN NEUROPATHOLOGY ON COGNITIVE AGING TRAJECTORIES (2006) (0)
- Genome-wide screen for variants that modify the known relationship between cerebrospinal fluid Beta-Amyloid 42 and ptau levels (2012) (0)
- Heritability analyses show partial genetic overlap between (non‐Mendelian) early and late onset Alzheimer disease due to an intriguing APOE effect (2021) (0)
- Identification of multi‐issue protein quantitative trait loci (pQTLs) for Alzheimer disease (2020) (0)
- A rare coding variant in PLD3 confers high risk for Alzheimer's disease (2013) (0)
- Polygenic risk score penetrance & recurrence risk in familial Alzheimer disease. (2023) (0)
- The effects of Alzheimer's disease associated transferrin variants on APP metabolism (2010) (0)
- Abstract WMP113: Genetic Influences on Early Neurological Instability After Acute Ischemic Stroke (2016) (0)
- NOMINATION OF NOVEL CANDIDATE GENES FOR FAMILIAL LATE ONSET ALZHEIMER DISEASE AFTER EVALUATION OF GENE-BASED FAMILY-BASED METHODS (2018) (0)
- CLINICAL RISK RELATED TO CEREBRAL MICROHEMORRHAGES IN AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE: LONGITUDINAL RESULTS FROM THE DIAN STUDY (2017) (0)
- Prediction of Alzheimer’s disease using plasma RNA sequences (2020) (0)
- Peripheral blood mononuclear cell tissue factor (F3 gene) transcript levels and circulating extracellular vesicles are elevated in severe coronavirus 2019 (COVID-19) disease (2022) (0)
- Phospholipase d3 contributes to Alzheimer’s disease risk via disruption in app trafficking and Aβ generation (2015) (0)
- Multiomics approaches reveal a link between the MS4A gene loci, TREM2, and microglia function (2020) (0)
- STOP-GAIN VARIANT IN MICROGLIA-EXPRESSED GENE GMIP IS ASSOCIATED WITH EARLY-ONSET ALZHEIMER’S DISEASE (2018) (0)
- Title Association between genetic traits for immune-mediated diseases and Alzheimer disease Permalink (2016) (0)
- Abstract WMP6: Genetic Variation In KLF5 Is Associated With Initial Stress Glucose Ratio In Acute Ischemic Stroke (2023) (0)
- O2-06-06: SNPS in MAPT are associated with cerebrospinal fluid Tau levels, MAPT mRNA levels, and age at onset of late-onset Alzheimer's disease (2008) (0)
- Genetic Associations with Age at Dementia Onset in the PSEN1 E280A Colombian Kindred (2020) (0)
- THE EMERGING CEREBROSPINAL FLUID BIOMARKER SNAP-25 IS ELEVATED IN APOEε4 CARRIERS IN COGNITIVELY NORMAL INDIVIDUALS (2006) (0)
- Orderings of biomarker changes for Alzheimer disease in cognitively normal individuals from 18 to 101 years of age (2020) (0)
- Identification of blood eQTLs for AD risk loci (2020) (0)
- Epistatic Features and Machine Learning Improve Alzheimer’s Risk Prediction Over Polygenic Risk Scores (2023) (0)
- Genome-wide association analysis using cerebrospinal fluid Abeta42 levels as an endophenotype for Alzheimer's disease (2011) (0)
- rs5848 variant influences GRN mRNA levels in patients with Alzheimer's Disease. (2009) (0)
- DECODING VARIABILITY IN AGE-AT-SYMPTOMATIC-ONSET BETWEEN PARENTS AND CHILDREN WITH SPORADIC ALZHEIMER DISEASE DEMENTIA (2017) (0)
- La luz y nuestro concepto de causalidad. (2017) (0)
- Ascertaining perturbations in microglial expression profiles using single‐nuclei RNA‐seq from human brains (2020) (0)
- Impact of MAPT mutations on transcriptomic signatures of FTLD brains and patient‐derived pluripotent cell models (2021) (0)
- APOE Genotype is Associated with Cerebrospinal Fluid and Plasma APOE Levels But Not with APOE Expression Levels (2011) (0)
- NOVEL CODING VARIANTS IN TREM2 INCREASE RISK FOR ALZHEIMER'S DISEASE (2014) (0)
- Genetic Overlap Between Immune-Mediated Diseases and Alzheimer’s Disease (S21.004) (2016) (0)
- QUANTIFYING THE CONTRIBUTIONS OF HERITABLE AND NON-HERITABLE FACTORS TO AGE-AT-ONSET OF ALZHEIMER DEMENTIA IN ADULT CHILDREN OF AFFECTED PARENTS (2018) (0)
- Correction to: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience (2018) (0)
- Single‐nuclei RNA‐seq of brains carriers of high‐risk variants and Mendelian mutations (2020) (0)
- A Mendelian randomization approach to characterize overlap in the pathophysiology of neurological disorders (2020) (0)
- CEREBROSPINAL FLUID ENDOPHENOTYPES PROVIDE INSIGHT INTO BIOLOGY UNDERLYING ALZHEIMER'S DISEASE (2017) (0)
- NUCLEOSKELETON DYSREGULATION IS MEDIATED BY LMNA IN ALZHEIMER’S DISEASE (2018) (0)
- ALZHEIMER'S DISEASE SEQUENCING PROJECT: SEARCH FOR ALZHEIMER'S DISEASE RESILIENCE GENES THAT MAY MODIFY DISEASE SUSCEPTIBILITY IN SPECIFIC APOE GENOTYPE BACKGROUNDS (2016) (0)
- Novel genetic risk factor for Alzheimer's disease progression [abstract] (2010) (0)
- UTILITY OF PERFUSION PET MODELS AS MEASURE OF NEURODEGENERATION IN AN AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE POPULATION: REPORT FROM THE DIAN STUDY (2017) (0)
- Alzheimer‐associated circular RNA circHOMER1 regulates synaptic gene expression and cognition (2020) (0)
- Sex differences in genetic predictors of resilience to Alzheimer’s disease (2020) (0)
- Late‐onset Alzheimer's disease‐associated gene, CPAMD8, increases B‐CTF and affects APP processing through regulation of the autophagy‐lysosome pathway (2020) (0)
- EMF-3 Genetic Architecture of Human Ischemic Stroke (2014) (0)
- RESOURCE OF MULTIPLEX AFRICAN AMERICAN FAMILIES FOR WHOLE-GENOME SEQUENCING (2017) (0)
- A potential endophenotype for Alzheimer’s disease: Cerebrospinal fluid clusterin (2015) (0)
- Polygenic risk scores can predict AD‐related pathologies (2020) (0)
- Proteome Wide Association Studies of LRRK2 variants identify novel causal and druggable for Parkinsons disease (2023) (0)
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes (2018) (0)
- CLINICAL RISK RELATED TO CEREBRAL MICROHEMORRHAGES IN AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE: LONGITUDINAL RESULTS FROM THE DIAN STUDY (2017) (0)
- EARLY RESTING-STATE NETWORK DYSFUNCTION IN APOE ε4 CARRIERS WITHOUT BIOMARKER EVIDENCE OF ALZHEIMER’S DISEASE IS RELATED TO SUBCLINICAL TAU CHANGES (2019) (0)
- BDNF VAL66MET INCREASES RATE OF MEMORY DECLINE, HIPPOCAMPAL VOLUME LOSS AND TAU ACCUMULATION IN AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE (2017) (0)
- Cerebrospinal heart fatty-acid–binding protein as a biomarker for Alzheimer's disease (2013) (0)
- Sex‐specific genetic predictors of memory, executive function, and language performance (2022) (0)
- A large‐scale, whole genome sequencing study of unexplained early‐onset Alzheimer disease (2021) (0)
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (0)
- Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia (2018) (0)
- App processing genes case-control screening and functional analysis in Alzheimer’s disease (2015) (0)
- THE ATN FRAMEWORK AND POLYGENIC SCORES OF AD ENDOPHENOTYPES (2019) (0)
- JAMA Neurology Peer Reviewers in 2016. (2017) (0)
- Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels (2018) (0)
- The National Institute on Aging Late Onset Alzheimer's Disease Family Based Study: A Critical Component of the International Effort to Understand Alzheimer's Disease (2021) (0)
- INTEGRATIVE ANALYSIS POINTS TO AGFG2 AS A NOVEL PLAYER IN THE PATHOLOGY OF ALZHEIMER DISEASE (2019) (0)
- Genome-wide association, Mendelian Randomization and polygenic risk score studies converge on a role of beta-amyloid and APOE locus in Parkinson disease (2020) (0)
- MAPT haplotypes modify the association between head injury and risk of Alzheimer’s disease (2015) (0)
- Castellano 2011 Sci Transl Med-1 (2015) (0)
- SNPs associated with CSF tau levels modify rate of progression in Alzheimer's disease (2010) (0)
- DIAGNOSTIC GROUPS TOWARDS P1-265 RATES OF PROGRESSION BETWEEN ALZHEIMER’S DISEASE: COMPARISON BETWEEN COHORT STUDIES (2017) (0)
- BRAIN TRANSCRIPTOMICS STUDY REVEALS DIFFERENTIAL EXPRESSION OF THE THREE TREM2 TRANSCRIPT IN AD AND TREM2 MUTATION CARRIERS (2018) (0)
- Identification of genetic variants associated with Alzheimer's disease: Progression rate (2015) (0)
- NOVEL RARE VARIANTS IN KNOWN GENES, A LOOK INTO THE FAMILIAL ALZHEIMER SEQUENCING (FASE) PROJECT (2016) (0)
- Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European–Americans (2015) (0)
- P1-054 AN EXPLORATION OFA FUNCTIONAL UNIT OF DNA METHYLATION IN THE AGING BRAIN (2013) (0)
- NOVEL CANDIDATE VARIANTS IN LOAD DETECTED BY THE FAMILIAL ALZHEIMER SEQUENCING (FASE) PROJECT (2017) (0)
- Relationships between hourly cognitive variability and risk of Alzheimer's disease revealed with mixed-effects location scale models. (2023) (0)
- TMEM106B gene polymorphism is associated with age at onset in granulin mutation carriers and plasma granulin protein levels in healthy individuals (2010) (0)
- Abstract 76: Genome Wide Association Study of Early Neurological Deterioration after Acute Ischemic Stroke Defines the Interferon-Stimulated Gene IFIT1 as a Neuroprotective Factor (2014) (0)
- Cell specific peripheral immune responses predict survival in critical COVID-19 patients (2022) (0)
- Multimodal genome‐wide meta‐analysis of brain amyloidosis reveals heterogeneity across CSF, PET, and pathological amyloid measures (2020) (0)
- LINKAGE AND WHOLE GENOME SEQUENCE ANALYSIS OF ALZHEIMER'S DISEASE RESILIENCE AND RISK (2016) (0)
- UTILITY OF PERFUSION PET MODELS AS MEASURES OF NEURODEGENERATION IN AN AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE POPULATION: REPORT FROM THE DIAN STUDY (2017) (0)
- Autosomal Recessive Alzheimer’s disease (arAD): homozygosity mapping of genomic regions containing arAD loci (2020) (0)
- Amyloid load increase and cerebral microbleed prevalence differ as a function of the position of the mutation within the PSEN1 coding sequence (2015) (0)
- Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (2019) (0)
- Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American cohort (2012) (0)
- Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study (2020) (0)
- BRAIN SOMATIC MOSAICISM IN 17Q21.31 MAPT H1-ASSOCIATED ALZHEIMER’S DISEASE (2019) (0)
- APOE4 EFFECT ON LONGITUDINAL VOLUMETRICS AND PIB ACCUMULATION IN PRECLINICAL ALZHEIMER DISEASE (2017) (0)
- DYNAMIC RELATIONSHIPS BETWEEN “BIG FIVE” PERSONALITY TRAITS, ALZHEIMER’S DISEASE BIOMARKERS, AND COGNITION IN AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE (2016) (0)
- Cross‐modal associations between traditional and emerging CSF biomarkers and grey matter network disruption in autosomal dominant Alzheimer disease (2020) (0)
- A comprehensive analysis of dementia cerebrospinal fluid biomarkers using GWAs, polygenic risk scores and Mendelian randomization in Parkinson’s disease (2020) (0)
- PHOSPHOLIPASE D3 CONTRIBUTES TO ALZHEIMER’S DISEASE RISK VIA DISRUPTION OF Aβ CLEARANCE THROUGH THE LYSOSOME (2017) (0)
- Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity (2020) (0)
- APOE4 EFFECT ON LONGITUDINAL VOLUMETRICS AND PIB ACCUMULATION IN PRECLINICAL ALZHEIMER DISEASE (2017) (0)
- Sex differences in APOE effects on cognition are domain‐specific (2022) (0)
- REPLICATION OF RARE VARIANTS IN PLCG2, ABI3 AND TREM2 FOR ALZHEIMER DISEASE IN A EUROPEAN AMERICAN COHORT (2019) (0)
- A missense variant in SLC39A8 is associated with severe idiopathic scoliosis (2018) (0)
- ALZHEIMER'S DISEASE SEQUENCING PROJECT: SEARCH FOR ALZHEIMER'S DISEASE RESILIENCE GENES THAT MAY MODIFY DISEASE SUSCEPTIBILITY IN SPECIFIC APOE GENOTYPE BACKGROUNDS (2016) (0)
- CIRCULAR RNAS IN ALZHEIMER'S DISEASE BRAIN TISSUES (2018) (0)
- Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation (vol 25, pg 1859, 2018) (2020) (0)
- Effect of BDNFVal66Met on disease markers in dominantly inherited AD (2018) (0)
- Proteogenomic analysis of cerebrospinal fluid reveals causal role of proteins from the autophagy‐lysosome pathway in Parkinson’s disease (2020) (0)
- Amyloid load increase and cerebral microbleed prevalence differ as a function of the position of the mutation within the PSEN1 coding sequence (2015) (0)
- EXOME-SEQUENCING IN LATE-ONSET FAMILIES IDENTIFIED ADDITIONAL CANDIDATES GENES FOR ALZHEIMER'S DISEASE (2014) (0)
- Role of genetic variation on longitudinal imaging measures of Alzheimer's disease in the ADNI Cohort (2013) (0)
- ADSP Functional Genomics: from gene, to function to mechanisms and targets (2022) (0)
- Rare Genetic Variants in APP, PSEN1, PSEN2, GRN, APOE and MAPT Associated with CSF Aß and tau/ptau181 Levels in Patients with Late-Onset Alzheimer’s Disease (2011) (0)
- P4-084 GENOME-WIDE ASSOCIATION STUDY USING CEREBROSPINAL FLUID BIOMARKERS BETA- AMYLOID-42 AND PTAU181 IN GERMAN SAMPLES OFALZHEIMER’S DISEASE (2012) (0)
- Data Descriptor: Human whole exome genotype data for Alzheimer’s Disease (2022) (0)
- Implications and frequency of APP, PSEN1, PSEN2, GRN and MAPT mutation in a well-characterized series of late-onset Alzheimer families (2010) (0)
- Gantnerumab In-depth Outcomes (2020) (0)
- Author Correction: Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS (2018) (0)
- Pathogenic mechanism of Alzheimer?s disease (2014) (0)
- An APOE-independent cis-eSNP on chromosome 19q13.32 influences hippocampal structure, tau levels, and late-onset Alzheimer’s disease risk (2018) (0)
- LYSOSOMAL DYSFUNCTION IN STEM CELL MODELS OF TAUOPATHY (2019) (0)
- INCREASED CSF SOLUBLE TREM2 IS ASSOCIATED WITH AMELIORATED LONGITUDINAL COGNITIVE AND CLINICAL DECLINE IN ALZHEIMER'S DISEASE (2019) (0)
- TMEM106B PROTECTIVE VARIANT ASSOCIATED WITH INCREASED NEURONAL PROPORTION (2019) (0)
- Research Article Variants in PPP3R1 and MAPTare associated with more rapid functional decline inAlzheimer's disease: TheCache County Dementia Progression Study (2013) (0)
- O2-17-06 SAFETYAND TOLERABILITY OF CRENEZUMAB IN MILD-TO-MODERATE AD PATIENTS TREATEDWITH ESCALATING DOSES FOR UP TO 25 MONTHS (2017) (0)
- Sex differences in the genetic architecture underlying resilience in AD (2021) (0)
- REVIEW OF GWAS GENES AND POLYGENIC RISK SCORES (2018) (0)
- IMPACT OF REFERENCE REGION USED TO QUANTIFY AMYLOID BURDEN ON INTERPRETING THE RELATIONSHIP BETWEEN AMYLOID BURDEN AND GENETIC RISK FACTORS OF AD (2019) (0)
- DPP6 gene in European American Alzheimer s Disease (2020) (0)
- Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson’s Disease (2016) (0)
- Genome-wide association studies using cerebrospinal fluid biomarkers as an endophenotype for Alzheimer's disease (2012) (0)
- Genome-wide association studies of CSF biomarkers (2011) (0)
- SORL1 VARIANTS ACROSS ALZHEIMER’S DISEASE COHORTS IN EUROPEAN AMERICANS (2016) (0)
- Global system segregation enhances reserve in normal aging and Alzheimer’s disease (2020) (0)
- Abstract T P72: Baseline Variables Have Little Influence on Early Change in Neurological Status (ΔNIHSS) After Acute Ischemic Stroke: Basis For a Genetic Study (2015) (0)
- Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS (2017) (0)
- Multi‐tissue proteomic profiling for genetically defined Alzheimer disease cases (2021) (0)
- Genome‐wide DNA methylation analysis of autosomal dominantly inherited and sporadic Alzheimer disease brains (2021) (0)
- THE CONTRIBUTION OF SEX-SPECIFIC ASSOCIATIONS IN GENETIC STUDIES OF ALZHEIMER’S DISEASE PATHOLOGY (2018) (0)
- First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer’s disease: the Dominantly Inherited Alzheimer’s Network Study (2022) (0)
- Identification of genetic modifiers for Alzheimer disease: The Familial Alzheimer Sequencing (FASe) project (2021) (0)
- Proteomic Clusters Underlie Heterogeneity in Preclinical AD Progression (2022) (0)
- Discovery and validation of autosomal dominant Alzheimer’s disease mutations (2018) (0)
- Genetic Contributions to Early and Late Onset Ischemic Stroke (2021) (0)
- Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease. (2023) (0)
- Sex‐specific molecular profiling to understand pathology and identify causal genes and drug targets for Alzheimer’s disease (2022) (0)
- An enrichment of rare variants and the lysosomal pathways are important contributors to early onset Alzheimer disease (2021) (0)
- Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer's disease. (2023) (0)
- Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology (2019) (0)
- Amyloid‐Related Imaging Abnormalities in the DIAN‐TU‐001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease (2022) (0)
- LMNA‐mediated nucleoskeleton dysregulation in Alzheimer disease (2021) (0)
- Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease (2020) (0)
- Integrating functional genomics with genetics to understand the biology of ALS and FTD. (2022) (0)
- Cross-Sectional and Longitudinal Comparisons of Biomarkers and Cognition Among Asymptomatic Middle-Aged Individuals with a Parental History of Either Autosomal Dominant or Late Onset Alzheimer Disease (2021) (0)
- Polygenic risk scores for Alzheimer’s disease predict MMSE decline in APOE4 carriers and noncarriers and the impact of sample overlap with GWAS summary statistics (2021) (0)
- The location of PSEN1 pathogenic variants in transmembrane vs. cytoplasmic domains may alter neurodegenerative and cognitive trajectories: Findings from the DIAN study (2021) (0)
This paper list is powered by the following services:
Other Resources About Carlos Cruchaga
What Schools Are Affiliated With Carlos Cruchaga?
Carlos Cruchaga is affiliated with the following schools:
