Carlos Martı́nez-a.

Carlos Martı́nez-a.'s AcademicInfluence.com Rankings

Carlos Martı́nez-a.

Biology

#10280

World Rank

#13593

Historical Rank

Developmental Biology

#127

World Rank

#135

Historical Rank

Cell Biology

#479

World Rank

#491

Historical Rank

Molecular Biology

#1481

World Rank

#1508

Historical Rank

biology Degrees

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Biology

Carlos Martı́nez-a.'s Degrees

PhD Molecular Biology University of California, San Francisco
Bachelors Biochemistry University of California, Berkeley

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Carlos Martı́nez-a.'s Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7 (2007) (625)
The Coordinated Action of CC Chemokines in the Lung Orchestrates Allergic Inflammation and Airway Hyperresponsiveness (1998) (594)
Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization (2001) (520)
Pathogens: raft hijackers (2003) (487)
T Cell‐Dependent B Cell Activation (1984) (479)
Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors. (1996) (473)
Chemokine receptor homo‐ or heterodimerization activates distinct signaling pathways (2001) (459)
The chemokine SDF‐lα triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway (1999) (431)
Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation. (2001) (415)
Membrane raft microdomains mediate lateral assemblies required for HIV‐1 infection (2000) (367)
T cell costimulation by chemokine receptors (2005) (359)
Membrane raft microdomains mediate front–rear polarity in migrating cells (1999) (333)
Conserved regulation of proximodistal limb axis development by Meis1/Hth (1999) (332)
PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus (2005) (332)
Cc Chemokine Receptor (Ccr)3/Eotaxin Is Followed by Ccr4/Monocyte-Derived Chemokine in Mediating Pulmonary T Helper Lymphocyte Type 2 Recruitment after Serial Antigen Challenge in Vivo (2000) (326)
Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. (2000) (318)
Statins Inhibit HIV-1 Infection by Down-regulating Rho Activity (2004) (294)
Forkhead transcription factors contribute to execution of the mitotic programme in mammals (2001) (293)
APRIL modulates B and T cell immunity. (2002) (288)
DNA polymerase mu (Pol μ), homologous to TdT, could act as a DNA mutator in eukaryotic cells (2000) (273)
Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3‐kinase (1998) (264)
Concerted Activity of Tyrosine Phosphatase SHP-2 and Focal Adhesion Kinase in Regulation of Cell Motility (1999) (263)
Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I (2001) (259)
The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism (2001) (252)
Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing. (2004) (251)
The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2. (1999) (244)
Dynamic redistribution of raft domains as an organizing platform for signaling during cell chemotaxis (2004) (242)
CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses. (2001) (242)
The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo. (2005) (240)
Role of the Pi3k Regulatory Subunit in the Control of Actin Organization and Cell Migration (2000) (237)
The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptor. (1998) (233)
Polarization of Chemokine Receptors to the Leading Edge during Lymphocyte Chemotaxis (1997) (231)
Identification of Insulin-like Growth Factor-binding Protein-1 as a Potential Physiological Substrate for Human Stromelysin-3* (1997) (225)
The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development (2000) (223)
CD69 downregulates autoimmune reactivity through active transforming growth factor-beta production in collagen-induced arthritis. (2003) (203)
The Matrix Metalloproteinase-9 Regulates the Insulin-like Growth Factor-triggered Autocrine Response in DU-145 Carcinoma Cells* (1999) (196)
Identification of amino acid residues crucial for chemokine receptor dimerization (2004) (186)
Implication of calpain in caspase activation during B cell clonal deletion (1999) (185)
Increased phosphoinositide 3‐kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo (2000) (184)
Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis. (1999) (183)
Enhanced Antitumor Immunity in Mice Deficient in CD69 (2003) (182)
The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression. (2002) (182)
APRIL promotes B-1 cell-associated neoplasm. (2004) (180)
Filamin-A regulates actin-dependent clustering of HIV receptors (2007) (177)
Influence of the CCR2-V64I Polymorphism on Human Immunodeficiency Virus Type 1 Coreceptor Activity and on Chemokine Receptor Function of CCR2b, CCR3, CCR5, and CXCR4 (1998) (174)
Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2. (1998) (173)
Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells. (1997) (169)
Antagonism between extradenticle function and Hedgehog signalling in the developing limb (1998) (164)
Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface (2004) (162)
An endogenous hybrid mRNA encodes TWE‐PRIL, a functional cell surface TWEAK–APRIL fusion protein (2002) (160)
A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate–mediated egress (2007) (158)
CXCR3 Chemokine Receptor Distribution in Normal and Inflamed Tissues: Expression on Activated Lymphocytes, Endothelial Cells, and Dendritic Cells (2001) (157)
STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3‐related genes flanking the Williams‐Beuren syndrome deletion (2000) (155)
Impaired germinal center reaction in mice with short telomeres (2000) (154)
CCR5 Expression Influences the Progression of Human Breast Cancer in a p53-dependent Manner (2003) (147)
Protein phosphatase 1α is a Ras‐activated Bad phosphatase that regulates interleukin‐2 deprivation‐induced apoptosis (2000) (141)
Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus (1990) (140)
Ligand stabilization of CXCR4/δ‐opioid receptor heterodimers reveals a mechanism for immune response regulation (2008) (138)
HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization. (2000) (137)
Chemokine control of HIV-1 infection (1999) (135)
Similarities and Differences in RANTES- and (AOP)-RANTES–triggered Signals: Implications for Chemotaxis (1999) (132)
Notch activation stimulates migration of breast cancer cells and promotes tumor growth (2013) (130)
Chemokines integrate JAK/STAT and G‐protein pathways during chemotaxis and calcium flux responses (2003) (127)
CCR6 regulates EAE pathogenesis by controlling regulatory CD4+ T‐cell recruitment to target tissues (2009) (124)
Chemokine receptor dimerization: two are better than one. (2001) (124)
The amino-terminal domain of the CCR2 chemokine receptor acts as coreceptor for HIV-1 infection. (1997) (119)
Phosphatidic Acid Generation through Interleukin 2 (IL-2)-induced -Diacylglycerol Kinase Activation Is an Essential Step in IL-2-mediated Lymphocyte Proliferation (*) (1996) (119)
Functionally distinct subsets of human γ/δ T cells (1991) (118)
Cohesin component dynamics during meiotic prophase I in mammalian oocytes (2004) (117)
Roles of chemokines and receptor polarization in NK-target cell interactions. (1998) (115)
Inhibition of programmed cell death impairs in vitro vascular‐like structure formation and reduces in vivo angiogenesis (2002) (112)
Expression of CCR9 beta-chemokine receptor is modulated in thymocyte differentiation and is selectively maintained in CD8(+) T cells from secondary lymphoid organs. (2001) (112)
Bcl-3 Expression Promotes Cell Survival following Interleukin-4 Deprivation and Is Controlled by AP1 and AP1-Like Transcription Factors (2000) (111)
CCR7-mediated physiological lymphocyte homing involves activation of a tyrosine kinase pathway. (2003) (109)
The chemokine SDF‐1α triggers a chemotactic response and induces cell polarization in human B lymphocytes (1998) (107)
Calcium Influx through Receptor-operated Channel Induces Mitochondria-triggered Paraptotic Cell Death* 210 (2003) (107)
A Suggested Mechanism for T Lymphocyte Activation: Implications on the Acquisition of Functional Reactivities (1980) (103)
From rafts to crafts: membrane asymmetry in moving cells. (2003) (103)
Ras proteins: recent advances and new functions. (1999) (102)
Phenotypic and functional characteristics of hematopoietic cell lineages in CD69-deficient mice. (2000) (102)
Control of T helper 2 cell function and allergic airway inflammation by PKCzeta. (2005) (102)
Blocking of HIV-1 Infection by Targeting CD4 to Nonraft Membrane Domains (2002) (102)
Absence of CCR8 Does Not Impair the Response to Ovalbumin-Induced Allergic Airway Disease 1 (2003) (101)
Nanomechanics of the formation of DNA self-assembled monolayers and hybridization on microcantilevers. (2004) (101)
Leukocyte attraction through the CCR5 receptor controls progress from insulitis to diabetes in non‐obese diabetic mice (2004) (99)
lnterleukin-2-dependent autocrine proliferation in T-cell development (1989) (96)
CCR6 has a non‐redundant role in the development of inflammatory bowel disease (2003) (96)
Aiolos transcription factor controls cell death in T cells by regulating Bcl‐2 expression and its cellular localization (1999) (95)
T Cell Activation In Vivo Targets Diacylglycerol Kinase α to the Membrane: A Novel Mechanism for Ras Attenuation1 (2003) (95)
STAG2 and Rad21 mammalian mitotic cohesins are implicated in meiosis (2002) (94)
Specific SHP-2 partitioning in raft domains triggers integrin-mediated signaling via Rho activation (2002) (92)
A role for chemokine receptor transactivation in growth factor signaling (2001) (92)
CCR6 regulates CD4+ T-cell-mediated acute graft-versus-host disease responses. (2005) (91)
c-Myc regulates cell size and ploidy but is not essential for postnatal proliferation in liver. (2005) (90)
Statins Induce Regulatory T Cell Recruitment via a CCL1 Dependent Pathway1 (2008) (89)
Distinct expression and function of the novel mouse chemokine monocyte chemotactic protein-5 in lung allergic inflammation (1996) (88)
Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle (2010) (87)
Blocking HIV‐1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor (2004) (86)
Autocrine Production of IFN-γ by Macrophages Controls Their Recruitment to Kidney and the Development of Glomerulonephritis in MRL/lpr Mice1 (2002) (85)
GH3, a novel proapoptotic domain in Drosophila Grim, promotes a mitochondrial death pathway (2002) (85)
PTEN regulates motility but not directionality during leukocyte chemotaxis (2004) (83)
Establishment of idiotypic helper T-cell repertoires early in life (1985) (83)
Lck is necessary and sufficient for Fas-ligand expression and apoptotic cell death in mature cycling T cells. (1997) (83)
Coordinated Involvement of Mast Cells and T Cells in Allergic Mucosal Inflammation: Critical Role of the CC Chemokine Ligand 1:CCR8 Axis (2007) (81)
Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice (1991) (79)
Functional Inactivation of CXC Chemokine Receptor 4–mediated Responses through SOCS3 Up-regulation (2002) (78)
A highly sensitive microsystem based on nanomechanical biosensors for genomics applications (2006) (78)
Drosophila grim induces apoptosis in mammalian cells (1998) (77)
Cell-cycle regulation in immunity, tolerance and autoimmunity. (2000) (77)
B-cell activation by helper cells is a two-step process (1981) (76)
Bcl-2 differentially targets K-, N-, and H-Ras to mitochondria in IL-2 supplemented or deprived cells: Implications in prevention of apoptosis (1999) (76)
Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement (2007) (75)
Dido gene expression alterations are implicated in the induction of hematological myeloid neoplasms. (2005) (74)
Pyrrolidine dithiocarbamate protects mice from lethal shock induced by LPS or TNF‐α (1999) (74)
A potential immune escape mechanism by melanoma cells through the activation of chemokine-induced T cell death (2001) (72)
Membrane raft microdomains in chemokine receptor function. (2001) (72)
Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor (1999) (71)
Ceramide-induced cell death is independent of the Fas/Fas ligand pathway and is prevented by Nur77 overexpression in A20 B cells (2000) (71)
Analysis of G-protein-coupled receptor dimerization following chemokine signaling. (2002) (71)
Expansion and clonal deletion of peripheral T cells induced by bacterial superantigen is independent of the interleukin‐2 pathway (1992) (70)
Phosphatidylinositol 3-Kinase Regulates the CD4/CD8 T Cell Differentiation Ratio1 (2003) (70)
Intermediate Affinity Interleukin-2 Receptor Mediates Survival via a Phosphatidylinositol 3-Kinase-dependent Pathway* (1997) (70)
Linomide, a novel immunomodulator that prevents death in four models of septic shock (1993) (70)
Conformational Changes Required in the Human Growth Hormone Receptor for Growth Hormone Signaling* (1997) (69)
Degradation of cellular mRNA is a general early apoptosis‐induced event (2002) (66)
Characterization of RANTES- and aminooxypentane-RANTES-triggered desensitization signals reveals differences in recruitment of the G protein-coupled receptor complex. (1999) (66)
Further evidence for coelomic‐associated b lymphocytes (1989) (66)
Regulation of macrophage activation and septic shock susceptibility via p21(WAF1/CIP1) (2009) (66)
Rho prevents apoptosis through Bcl‐2 expression: Implications for interleukin‐2 receptor signal transduction (1997) (65)
IL-2 signaling controls actin organization through Rho-like protein family, phosphatidylinositol 3-kinase, and protein kinase C-zeta. (1997) (64)
DIO-1 is a gene involved in onset of apoptosis in vitro, whose misexpression disrupts limb development. (1999) (63)
p21CIP1/WAF1 Controls Proliferation of Activated/Memory T Cells and Affects Homeostasis and Memory T Cell Responses1 (2007) (62)
p21 mediates macrophage reprogramming through regulation of p50-p50 NF-κB and IFN-β. (2016) (61)
Increased responsiveness of murine eosinophils to MIP‐1β (CCL4) and TCA‐3 (CCL1) is mediated by their specific receptors, CCR5 and CCR8 (2002) (60)
Human T‐Cell Precursors: Involvement of the IL‐2 Pathway in the Generation of Mature T Cells (1988) (59)
Co‐expression of Mac‐1 and p150,95 on CD5+ B cells. Structural and functional characterization in a human chronic lymphocytic leukemia (1988) (59)
Ras Proteins: Recent Advances and New Functions (1999) (56)
Characterization of the Immunostimulatory Properties of Leishmania infantum HSP70 by Fusion to theEscherichia coli Maltose-Binding Protein in Normal andnu/nu BALB/c Mice (1998) (56)
Bcl-2 Targets Protein Phosphatase 1α to Bad1 (2001) (56)
Caspase activation by BCR cross‐linking in immature B cells: differential effects on growth arrest and apoptosis (1999) (56)
The Identification of Phosphatidylinositol 3,5-bisphosphate in T-lymphocytes and Its Regulation by Interleukin-2* (1999) (55)
B cell participation in the recursive selection of T cell repertoires (1988) (55)
Down‐regulation of the β‐chemokine receptor CCR6 in dendritic cells mediated by TNF‐α and IL‐4 (1999) (55)
A “Trans” Perspective on the Control of Immunoglobulin C Gene Expression (1982) (53)
Role of Akt and c-Jun N-terminal kinase 2 in apoptosis induced by interleukin-4 deprivation. (1998) (51)
ACRATA: a novel electron transfer domain associated to apoptosis and cancer (2004) (51)
Dynamic Regulation of CXCR1 and CXCR2 Homo- and Heterodimers1 (2009) (50)
Ras activation leads to cell proliferation or apoptotic cell death upon interleukin‐2 stimulation or lymphokine deprivation, respectively (1997) (50)
Signal Transduction Pathways Involved in B‐Cell Induction (1993) (49)
B cell receptor cross-linking prevents Fas-induced cell death by inactivating the IL-1 beta-converting enzyme protease and regulating Bcl-2/Bcl-x expression. (1997) (48)
Mastering time and space: immune cell polarization and chemotaxis. (2005) (48)
Tumor Suppressor p53 Mediates Apoptotic Cell Death Triggered by Cyclosporin A* (2002) (48)
Regulation of Diacylglycerol Kinase α by Phosphoinositide 3-Kinase Lipid Products* (2003) (48)
IL-2-induced cellular events. (1998) (47)
Cells on the Move: A Dialogue Between Polarization and Motility (2000) (47)
Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability (2007) (47)
Dido3 PHD modulates cell differentiation and division. (2013) (46)
Linomide inhibits programmed cell death of peripheral T cells in vivo (1994) (46)
Centromere fission, not telomere erosion, triggers chromosomal instability in human carcinomas (2011) (46)
c-Myc is essential for hematopoietic stem cell differentiation and regulates Lin(-)Sca-1(+)c-Kit(-) cell generation through p21. (2007) (45)
c-Myc-deficient B lymphocytes are resistant to spontaneous and induced cell death (2004) (44)
Inhibition of dynamin prevents CCL2-mediated endocytosis of CCR2 and activation of ERK1/2. (2009) (44)
The Bcl-2 gene is differentially regulated by IL-2 and IL-4: role of the transcription factor NF-AT (1998) (43)
The Participation of B Cells and Antibodies in the Selection and Maintenance of T Cell Repertoires (1988) (43)
Analysis of Post-translational CCR8 Modifications and Their Influence on Receptor Activity* (2004) (43)
In vivo administration of interleukin‐2 turns on anergic self‐reactive T cells and leads to autoimmune disease (1992) (43)
The Transient Expression of C-C Chemokine Receptor 8 in Thymus Identifies a Thymocyte Subset Committed to Become CD4+ Single-Positive T Cells1 (2001) (43)
Dido3-dependent HDAC6 targeting controls cilium size (2014) (42)
CD69 limits early inflammatory diseases associated with immune response to Listeria monocytogenes infection (2010) (42)
From Apoptosis to Autoimmunity: Insights from the Signaling Pathways Leading to Proliferation or to Programmed Cell Death (1994) (41)
Dual role of Ras and Rho proteins: At the cutting edge of life and death (1998) (40)
Maternal transmission of idiotypic network interactions selecting available T cell repertoires (1986) (40)
Chemokine receptor oligomerization: a further step toward chemokine function. (2012) (39)
Death Inducer-Obliterator 1 Triggers Apoptosis after Nuclear Translocation and Caspase Upregulation (2003) (39)
Critical role of Ras in the proliferation and prevention of apoptosis mediated by IL-2. (1996) (39)
Decreased TcR‐CD3+ T cell numbers in healthy aged humans. Evidence that T cell defects are masked by a reciprocal increase of TcR‐CD3−CD2+ natural killer cells (1988) (38)
Chromothripsis: Breakage-fusion-bridge over and over again (2013) (37)
Identification on Mouse Chromosome 8 of New β-Defensin Genes with Regionally Specific Expression in the Male Reproductive Organ* (2004) (37)
The chemokine SDF-1alpha triggers a chemotactic response and induces cell polarization in human B lymphocytes. (1998) (36)
Merotelic attachments and non-homologous end joining are the basis of chromosomal instability (2010) (36)
The Prokaryotic β-Recombinase Catalyzes Site-specific Recombination in Mammalian Cells* (1999) (36)
Cell surface CD28 levels define four CD4+ T cell subsets: abnormal expression in rheumatoid arthritis. (2001) (35)
Nuclear Apaf‐1 and cytochrome c redistribution following stress‐induced apoptosis (2002) (35)
Cholesterol domains regulate the actin cytoskeleton at the leading edge of moving cells. (2004) (34)
Lessons from immunological, biochemical, and molecular pathways of the activation mediated by IL-2 and IL-4. (1996) (34)
SPOC: A widely distributed domain associated with cancer, apoptosis and transcription (2004) (33)
The Association of Aiolos Transcription Factor and Bcl-xL Is Involved in the Control of Apoptosis (2001) (33)
IMMUNOLOGICAL CONSEQUENCES OF HIV INFECTION: ADVANTAGE OF BEING LOW RESPONDER CASTS DOUBTS ON VACCINE DEVELOPMENT (1988) (33)
Are aneuploidy and chromosome breakage caused by a CINgle mechanism? (2010) (32)
Dual role of ceramide in the control of apoptosis following IL-2 withdrawal. (1998) (32)
Signaling through CD43 induces natural killer cell activation, chemokine release, and PYK-2 activation. (1999) (32)
Isolation and characterization of (gamma, delta) CD4+ T cell clones derived from human fetal liver cells (1989) (32)
A Bax/Bak-independent Mitochondrial Death Pathway Triggered by Drosophila Grim GH3 Domain in Mammalian Cells* (2004) (32)
Chemokine Receptor 2 Blockade Prevents Asthma in a Cynomolgus Monkey Model (2008) (32)
Lck Unique Domain Influences Lck Specificity and Biological Function (*) (1995) (31)
Diminished Natural Killer Activity in Pregnancy: Modulation by Interleukin 2 and Interferon γ (1987) (31)
The Role of IFN-β during the Course of Sepsis Progression and Its Therapeutic Potential (2017) (31)
Linomide prevents the lethal effect of anti-Fas antibody and reduces Fas-mediated ceramide production in mouse hepatocytes. (1996) (31)
Cross‐linking of surface IgM or IgD causes differential biological effects in spite of overlap in tyrosine (de)phosphorylation profile (1992) (31)
A generalized caspase inhibitor disrupts early mammalian development. (2005) (31)
Selective expansion of T cells bearing the γ/δ receptor and expressing an unusual repertoire in the synovial membrane of patients with rheumatoid arthritis (1991) (31)
Death inducer obliterator protein 1 in the context of DNA regulation (2005) (31)
A functional idiotypic network of T helper cells and antibodies, limited to the compartment of “naturally” activated lymphocytes in normal mice (1987) (31)
Membrane Translocation of Protein Kinase Cθ during T Lymphocyte Activation Requires Phospholipase C-γ-generated Diacylglycerol* (2003) (30)
Activation of the epidermal growth factor signalling pathway by tissue plasminogen activator in pancreas cancer cells (2007) (30)
Ontogenic characterization of thymic B lymphocytes. Analysis in different mouse strains (1990) (29)
9 – The Protein A Plaque Assay for the Detection of Immunoglobulin-Secreting Cells (1981) (29)
Domain architecture of the bacteriophage phi29 connector protein. (1999) (28)
Detection of apoptosis and apoptosis-associated alterations (1996) (28)
Role of the PI 3 K Regulatory Subunit in the Control of Actin Organization and Cell Migration (2000) (28)
New Insights into Host Factor Requirements for Prokaryotic β-Recombinase-mediated Reactions in Mammalian Cells* (2001) (28)
Immune networks. Frequencies of antibody- and idiotype-producing B cell clones in various steady states (1981) (28)
Linomide administration to mice attenuates the induction of nitric oxide synthase elicited by lipopolysaccharide-activated macrophages and prevents nephritis in MRL/Mp-lpr/lpr mice. (1997) (28)
Idiotypic Multireactivity of ‘Natural’ Antibodies (1987) (27)
Molecular analysis of HIV‐1 gp120 antibody response using isotype IgM and IgG phage display libraries from a long‐term non‐progressor HIV‐1‐infected individual (1999) (27)
Antitumor effects of a monoclonal antibody to human CCR9 in leukemia cell xenografts (2014) (27)
Ipr T cells vaccinate against lupus in MRL/lpr mice (1992) (26)
Sequential Loading of Cohesin Subunits during the First Meiotic Prophase of Grasshoppers (2007) (26)
Immunological Self‐Tolerance: An Analysis Employing Cytokines or Cytokine Receptors Encoded by Transgenes or a Recombinant Vaccinia Virus (1991) (26)
Transplanted Long-Term Cultured Pre-Bi Cells Expressing Calpastatin Are Resistant to B Cell Receptor–Induced Apoptosis (2001) (25)
Distribution and characteristics of betaII tubulin-enriched microtubules in interphase cells. (1999) (25)
Identification and Characterization of a Potent, Selective Nonpeptide Agonist of the CC Chemokine Receptor CCR8 (2006) (25)
Association of phosphatidylinositol 3 kinase to protein kinase C ζ during interleukin‐2 stimulation (1996) (25)
The fail-safe paradigm of immunological self-tolerance (1991) (24)
Synaptonemal complex assembly and H3K4Me3 demethylation determine DIDO3 localization in meiosis (2009) (24)
Selection of antibody probes to correlate protein sequence domains with their structural distribution (2008) (24)
CD69 targeting differentially affects the course of collagen‐induced arthritis (2006) (24)
CXCR4-mediated Suppressor of Cytokine Signaling Up-regulation Inactivates Growth Hormone Function* (2004) (23)
Polymerase μ is up‐regulated during the T cell‐dependent immune response and its deficiency alters developmental dynamics of spleen centroblasts (2005) (22)
Growth hormone prevents the development of autoimmune diabetes (2013) (22)
Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-γ production (2015) (22)
CCR6 regulates the function of alloreactive and regulatory CD4+ T cells during acute graft-versus-host disease (2006) (22)
Human cord blood CD34+Pax-5+ B-cell progenitors: single-cell analyses of their gene expression profiles. (2003) (21)
Opioids Trigger α5β1 Integrin-Mediated Monocyte Adhesion1 (2006) (21)
Diacylglycerol kinase α activity promotes survival of CD4+ 8+ double positive cells during thymocyte development (2002) (21)
Vaccinia virus-induced apoptosis in immature B lymphocytes: role of cellular Bcl-2. (1998) (21)
Modification of Emerging Repertoires by Immunosuppression in Immunodeficient Mice Results in Autoimmunity (1986) (21)
Low IgG2 and polysaccharide response in a T cell receptor expression defect (1990) (21)
A human immunodeficiency virus type 1 Env-granulocyte-macrophage colony-stimulating factor fusion protein enhances the cellular immune response to Env in a vaccinia virus-based vaccine. (1999) (21)
Distinctive patterns of naïve/memory subset distribution and cytokine expression in CD4 T lymphocytes in ZAP‐70 B‐chronic lymphocytic patients (2013) (21)
Activation of the interleukin 2 pathway precedes CD3‐T cell receptor expression in thymic development. Differential growth requirements of early and mature intrathymic subpopulations (1989) (21)
Interleukin 2 pathway is autonomously activated in human T11+3−4−6−8− thymocytes (1987) (21)
Ablation of Dido3 compromises lineage commitment of stem cells in vitro and during early embryonic development (2011) (21)
CD2‐CD48 interaction prevents apoptosis in murine B lymphocytes by up‐regulating bcl‐2 expression (1994) (20)
Dido3-dependent SFPQ recruitment maintains efficiency in mammalian alternative splicing (2019) (20)
Involvement of the interleukin 4 pathway in the generation of functional gamma delta T cells from human pro-T cells. (1991) (20)
IL-2 deprivation triggers apoptosis which is mediated by c-Jun N-terminal kinase 1 activation and prevented by Bcl-2 (1999) (20)
Regulation of diacylglycerol kinase alpha by phosphoinositide 3-kinase lipid products. (2003) (19)
CD 69 downregulates autoimmune reactivity through active transforming growth factor-β production in collagen-induced arthritis (2003) (19)
Drosophila cohesins DSA1 and Drad21 persist and colocalize along the centromeric heterochromatin during mitosis (2004) (19)
Enterotoxin septic shock protection and deficient T helper 2 cytokine production in growth hormone transgenic mice. (1996) (19)
Age-dependent changes in the response to staphylococcal enterotoxin B. (1994) (19)
Differential Growth Requirements and Effector Functions of α/β and γ/δ Human T Cells (1989) (18)
DIDO as a Switchboard that Regulates Self-Renewal and Differentiation in Embryonic Stem Cells (2017) (18)
Role of NF-kappaB in the control of apoptotic and proliferative responses in IL-2-responsive T cells. (1997) (17)
Tyr³²³-dependent p38 activation is associated with rheumatoid arthritis and correlates with disease activity. (2011) (17)
Absence of peripheral clonal deletion and anergy in immune responses of T cell‐reconstituted athymic mice (1994) (17)
Expression analysis of the thyrotropin‐releasing hormone receptor (TRHR) in the immune system using agonist anti‐TRHR monoclonal antibodies (1999) (17)
An IL‐2 receptor β subdomain that controls Bcl‐XL expression and cell survival (1999) (17)
Insulin-like growth factor I-triggered cell migration and invasion are mediated by matrix metalloproteinase-9. (1999) (17)
Functional Epitope Mapping of Insulin-Like Growth Factor I (IGF-I) by Anti-IGF-I Monoclonal Antibodies. (1997) (16)
Functional double‐negative T cells in the periphery express T cell receptor Vβ gene products that cause deletion of single‐positive T cells (1993) (16)
Apoptosis in Immunology (1995) (15)
The role of IL‐4 in the staphylococcal enterotoxin B‐triggered immune response: increased susceptibility to shock and deletion of CD8Vβ8+ T cells in IL‐4 knockout mice (1999) (15)
Apaf‐1 localization is modulated indirectly by Bcl‐2 expression (2001) (15)
A framework for computational and experimental methods: Identifying dimerization residues in CCR chemokine receptors (2005) (13)
Nitric oxide regulates clonal expansion and activation-induced cell death triggered by staphylococcal enterotoxin B (1997) (13)
Expression of the p75 interleukin 2‐binding protein on CD34‐8‐Tac‐ cells from autoimmune MRL/MP‐lpr/lpr mice (1989) (13)
Highly Efficient Expression of Proteins Encoded by Recombinant Vaccinia Virus in Lymphocytes (1991) (12)
Chemokines: the times they are a-changin'. (2001) (12)
Decrease in cAMP Levels Promoted by CD48–CD2 Interaction Correlates with Inhibition of Apoptosis in B Cells (1996) (12)
Suppression of HIV‐1 infection in linomide‐treated SCID‐hu‐PBL mice (1998) (12)
Inside the thymus, Mls antigen is exclusively presented by B lymphocytes. (1990) (11)
Interleukin‐2 stimulates a late increase in phosphatidic acid production in the absence of phospholipase D activation (1998) (11)
Developmental Expression of IL-2-Receptor Light Chain (CD25) in the Chicken Embryo (1991) (11)
Clonal deletion and anergy: from models to reality. 42nd forum in immunology. (1992) (11)
On How Fas Apoptosis-Independent Pathways Drive T Cell Hyperproliferation and Lymphadenopathy in lpr Mice (2017) (11)
Acquisition of CD40 Expression During Murine B‐Cell Differentiation (1996) (11)
Chemokine signaling defines novel targets for therapeutic intervention. (2005) (11)
Selective Expansion of a CD3+CD4‐CD8‐ Subpopulation in Clinical Groups Associated with Human Immunodeficiency Virus Infection (1987) (11)
p38α regulates cytokine‐induced IFNγ secretion via the Mnk1/eIF4E pathway in Th1 cells (2017) (11)
Co-regulation analysis of closely linked genes identifies a highly recurrent gain on chromosome 17q25.3 in prostate cancer (2008) (10)
Anti‐Vβ8 antibodies induce and maintain staphylococcal enterotoxin B‐triggered Vβ8+ T cell anergy (1999) (10)
Cell death during lymphocyte development and activation. (2003) (10)
Identity of PB76 differentiation antigen and lymphocyte alkaline phosphatase (1990) (10)
Waves of B‐Lymphopoiesis in the Establishment of the Mouse B‐Cell Compartment (1991) (10)
Inhibitor of Apoptosis Protein from Orgyia pseudotsugata Nuclear Polyhedrosis Virus Provides a Costimulatory Signal Required for Optimal Proliferation of Developing Thymocytes1 (2002) (9)
A Hypothesis for the Selection of Available Repertoires: T‐Cell Network Early in the Intrathymic Differentiation (1986) (8)
Inhibitory Role of Growth Hormone in the Induction and Progression Phases of Collagen-Induced Arthritis (2018) (8)
Inducible model for β-six-mediated site-specific recombination in mammalian cells (2006) (8)
Apoptosis as a Scaffold for Building up the B Cell Repertoire (2000) (7)
The role of immunoglobulin receptors in “cognate” T‐B cell collaboration (1986) (7)
Early T-cell development (1993) (7)
Growth Hormone Reprograms Macrophages toward an Anti-Inflammatory and Reparative Profile in an MAFB-Dependent Manner (2020) (7)
A common idiotope on T cell receptors and antibodies expressed in the absence of network selection (1987) (7)
Effect of Anti-δ Antibodies on Clonal Expansion and Maturation of B Lymphocytes (1981) (7)
Activation of Helper T Cells for B Lymphocytes in Primary Mixed Lymphocyte Cultures (1983) (7)
Impact of the Innate Inflammatory Response on ICU Admission and Death in Hospitalized Patients with COVID-19 (2021) (6)
Coelomic and Bone Marrow‐Derived B Cells (1992) (6)
Identification and Characterization of a Potent , Selective Nonpeptide Agonist of the CC Chemokine Receptor CCR 8 (2005) (6)
The expression of Death Inducer-Obliterator (DIDO) variants in Myeloproliferative Neoplasms. (2016) (6)
In Vivo Activation of T‐Cell Induction into the Primed Phenotype and Programmed Cell Death by Staphylococcal Enterotoxin B (1996) (6)
An IL-2 receptor beta subdomain that controls Bcl-X(L) expression and cell survival. (1999) (6)
Membrane translocation of protein kinase Ctheta during T lymphocyte activation requires phospholipase C-gamma-generated diacylglycerol. (2003) (5)
Dido mutations trigger perinatal death and generate brain abnormalities and behavioral alterations in surviving adult mice (2015) (5)
Mitochondrial reactive oxygen is critical for IL-12/IL-18-induced IFN-γ production by CD4+ T cells and is regulated by Fas/FasL signaling (2022) (5)
Impaired stem cell differentiation and somatic cell reprogramming in DIDO3 mutants with altered RNA processing and increased R-loop levels (2021) (5)
ZAP-70 upregulation in transformed B cells after early pre-BI cell transplant into NOD/SCID mice (2005) (5)
Hapten specific helper T cells restricted by theI-E(C) subregion of the MHC (1980) (5)
Interplay between splicing and transcriptional pausing exerts genome-wide control over alternative polyadenylation (2021) (5)
In vivo site-specific recombination using the β-rec/six system six system six (2008) (5)
In vivo site-specific recombination using the beta-rec/six system. (2008) (4)
Distinctive patterns of naïve/memory subset distribution and cytokine expression in CD4 T lymphocytes in ZAP-70 B-chronic lymphocytic patients. (2013) (4)
Linking stem cells to chromosomal instability (2012) (4)
Still waiting for the end (2002) (4)
DNA microarrays: a bridge between genome sequence information and biological understanding (2002) (4)
Response to "On the dimerization of CCR5" (2005) (4)
Interactions of small B lymphocytes with unprimed noncytolytic T cells: dissociation between “presentation” and growth induction (1985) (4)
DeltahGHR, a novel biosafe cell surface-labeling molecule for analysis and selection of genetically transduced human cells. (2000) (4)
The identification of phosphatidylinositol-3,5 bisphosphate in T-lymphocytes and its regulation by interleukin-2 (1999) (4)
Back‐stimulation of B lymphocytes binding to helper T cell surface antigens (1988) (3)
The catalytic domain of pp56(lck), but not its regulatory domain, is sufficient for inducing IL-2 production. (1996) (3)
Exacerbated inflammatory responses in transgenic mice expressing an inhibitor of apoptosis protein (OpIAP) (2003) (3)
Role of Innate and Adaptive Cytokines in the Survival of COVID-19 Patients (2022) (3)
The role of I-A/E molecules in B-lymphocyte activation. II. Mechanism of inhibition of the responses to lipopolysaccharide by anti-I-A/E antibodies. (1987) (3)
Polyethylene glycol-modified IL-2 abrogates superantigen-induced anergy without affecting peripheral clonal deletion in vivo. (1996) (3)
Drug Testing in Cellular Chemotaxis Assays (2008) (3)
p21 Controls Proliferation of Activated/Memory T Cells and Affects Homeostasis and Memory T Cell Responses (2007) (3)
Meeting report: Mechanisms of cell death 2000 (2001) (2)
Corrigendum to "The expression of Death Inducer-Obliterator (DIDO) variants in Myeloproliferative Neoplasms" [Blood Cells Mol. Dis. 59 (2016) 25-30]. (2017) (2)
Ras-mediated cell proliferation and cell death: some clues from the interleukin-2 receptor system (1996) (2)
Mechanisms of Cell Death 2000 (2000) (2)
Abnormal Chemokine Receptor Profile on Circulating T Lymphocytes from Nonallergic Asthma Patients (2014) (2)
11 – A Helper Cell Assay of Cellular Antigens and Its Applications to Hapten-Specific T Cells (1981) (2)
Notch activation stimulates migration of breast cancer cells and promotes tumor growth (2013) (1)
A Model System for the Analysis of B‐Cell Activation and Effector T‐Cell Functions (1989) (1)
Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing (2022) (1)
G PROTEIN-COUPLED-RECEPTOR MEDIATED STAT ACTIVATION (2003) (1)
Tocilizumab efficacy in COVID-19 patients is associated with respiratory severity-based stages (2021) (1)
The original sin of T cells: Constitutive activation of the IL-2/IL-2R pathway early in intrathymic development (1990) (1)
Breakage-fusion-bridge over and over again (2016) (1)
Experimental Models of Septic Shock in the Mouse: The Effect of Linomide (1995) (1)
Mechanisms of cell death II : the Third Annual Conference of the International Cell Death Society (2000) (1)
DIDO3 acts at the interface of RNAPII transcription and chromatin structure regulation (2021) (1)
Mitochondrial oxidative stress drives IL-12/IL-18-induced IFN-γ production by CD4+ T cells and is controlled by Fas (2021) (1)
Chemokine receptor-mediated signal transduction (2006) (1)
Polarization in NK-Target Cell Interactions Roles of Chemokines and Receptor (2013) (0)
LPS-induced p21 is required for M2 polarization of endotoxin- tolerant macrophages and controls the accumulation of inhibitory p50/p50 NF-κB (INC6P.317) (2015) (0)
Leukocyte migration is guided by polarization of the chemokine receptors that act as sensors during lymphocyte chemotaxis (1997) (0)
High Aurora Kinase and Low Dido Levels Characterizes a Sub-Group of Chronic Lymphocytic Leukemia with Chromosomal Gains and High White Blood Cell Counts: Potential Inter-Regulatory Role of E2F1 and Mir-17-92 Cluster (2016) (0)
Frequencies ofAntibody- and Idiotype-producing B Cell Clones in Various Steady States* (1981) (0)
The Impact of Dido on the Epithelial-Mesenchymal Transition (2021) (0)
Use of retroviral vectors in lymphohemato-poietic lineage analysis (1996) (0)
Meeting on Signalling Networks in Immunity and Inflammation (2006) (0)
Questions on the Emergence of T-cell Repertoires (2020) (0)
G Protein-Coupled Receptors: Functional consequences of chemokine receptor dimerization (2010) (0)
Preface: Mechanisms of Cell Death 2000 (2000) (0)
Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing (2022) (0)
Antibody repertoire against HIV-1 gp120 triggered in nude and normal mice by GM-CSF/gp120 immunization. (1999) (0)
Correction to: Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing (2022) (0)
Use of delta opioid receptor agonists in the preparation of pharmaceutical compositions, pharmaceutical compositions containing them and their applications in treating tumors. (2006) (0)
Bioinformatic Analyses of the Dio Family of Proteins (2004) (0)
Salamanca, Spain Symposium (2005) (0)
CBA / N MICE BriefDefinitive Report DEVELOPMENT OF Ly-1 + B CELLS IN IMMUNODEFICIENT (2003) (0)
Correction to: Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing (2022) (0)
Insulin-like Growth Factor Axis Elements in Breast Cancer Progression (2001) (0)
Brains, cytokines and nightmares (1996) (0)
CD2 ligation abrogates antigen-independent apoptosis in B cells. (1996) (0)
Chromatin reader Dido3 regulates the genetic network of B cell differentiation (2021) (0)
Commentaryattachments and non-homologous end joining are the basis of chromosomal instability (2010) (0)
1093 Enhanced Antitumor Immunity in Mice Deﬁcient in (2003) (0)
MRL/lpr mice as a model of autoimmune diseases: mutiple strategies for immune intervention (1994) (0)
p21 suppresses autoimmunity by regulating ERK1/2 phosphorylation, NF-κB activation and IFNγ production in hyperactivated T cells (BA4P.141) (2015) (0)
Apoptosis in the Immune System (2005) (0)
Indications for an internal regulation in the immune system. (1980) (0)
Chemokine Signaling: The Functional Importance of Stabilizing Receptor Conformations (2005) (0)
Erratum: c-Myc-deficient B lymphocytes are resistant to spontaneous and induced cell death (2004) (0)
General Principles of Complex Biological Systems Operating in Immunology. Self-Responses Might Define the Boundaries of the Developing Immune System (1988) (0)
Contents, Vol. 97, 1992 (1992) (0)
2012 Landes Bioscience. Do not distribute. Linking stem cells to chromosomal instability (2012) (0)
Spain calls attention to EMBL (1993) (0)
Use of DNA priming and vaccinia virus boosting to trigger an efficient immune response to HIV-1 gp 120 Research (2001) (0)
Mother-Derived Selection of Immune Repertoires (2020) (0)

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