Carol J. Thiele
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American microbiologist
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Why Is Carol J. Thiele Influential?
(Suggest an Edit or Addition)According to Wikipedia, Carol Jeanne Thiele is an American microbiologist and cancer researcher specialized in the development of novel therapeutic strategies for pediatric tumors. She is chief of the cell and molecular biology section at the National Cancer Institute. She is a founding editor of the journal Cell Death & Differentiation.
Carol J. Thiele's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma (1985) (648)
- Adrenomedullin Expression in Human Tumor Cell Lines ITS POTENTIAL ROLE AS AN AUTOCRINE GROWTH FACTOR* (1996) (322)
- Repression of the gene encoding the TGF-β type II receptor is a major target of the EWS-FLI1 oncoprotein (1999) (318)
- The MYCN oncogene is a direct target of miR-34a (2008) (306)
- Glycogen synthase kinase 3β (GSK3β) mediates 6‐ hydroxydopamine‐induced neuronal death (2004) (287)
- MYCN and the epigenome (2013) (280)
- Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation (1984) (276)
- MS-27-275, an inhibitor of histone deacetylase, has marked in vitro and in vivo antitumor activity against pediatric solid tumors. (2002) (236)
- On Trk—The TrkB Signal Transduction Pathway Is an Increasingly Important Target in Cancer Biology (2009) (230)
- Expression of brain-derived neurotrophic factor and p145TrkB affects survival, differentiation, and invasiveness of human neuroblastoma cells. (1995) (214)
- Brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from chemotherapy-induced apoptosis via phosphatidylinositol 3'-kinase pathway. (2002) (195)
- The role of INI1 and the SWI/SNF complex in the development of rhabdoid tumors: meeting summary from the workshop on childhood atypical teratoid/rhabdoid tumors. (2002) (188)
- Neuroblastoma cells isolated from bone marrow metastases contain a naturally enriched tumor-initiating cell. (2007) (188)
- Brain-Derived Neurotrophic Factor Activation of TrkB Induces Vascular Endothelial Growth Factor Expression via Hypoxia-Inducible Factor-1α in Neuroblastoma Cells (2006) (185)
- Effect of imatinib mesylate on neuroblastoma tumorigenesis and vascular endothelial growth factor expression. (2004) (160)
- EZH2 Mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3, and NGFR. (2012) (155)
- Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine-induced neuronal death. (2004) (119)
- Differential protooncogene expression characterizes histopathologically indistinguishable tumors of the peripheral nervous system. (1987) (112)
- Induction of caspase 8 by interferon gamma renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB. (2003) (112)
- Indistinguishable patterns of protooncogene expression in two distinct but closely related tumors: Ewing's sarcoma and neuroepithelioma. (1988) (111)
- Credentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis. (2007) (111)
- Brain-derived neurotrophic factor activation of TrkB induces vascular endothelial growth factor expression via hypoxia-inducible factor-1alpha in neuroblastoma cells. (2006) (109)
- Topotecan blocks hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression induced by insulin-like growth factor-I in neuroblastoma cells. (2005) (105)
- Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma. (2007) (101)
- Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation (1988) (100)
- p27Kip1: a key mediator of retinoic acid induced growth arrest in the SMS–KCNR human neuroblastoma cell line (1998) (95)
- CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression (2011) (92)
- CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2 (2017) (89)
- Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo (2013) (89)
- Novel mutations in the p16/CDKN2A binding region of the cyclin-dependent kinase-4 gene. (1998) (86)
- Biologically relevant orthotopic neuroblastoma xenograft models: primary adrenal tumor growth and spontaneous distant metastasis. (2002) (85)
- Epigenetic Changes in Pediatric Solid Tumors: Promising New Targets (2012) (79)
- Neuroblastoma Cell Lines (1998) (76)
- retSDR1, a short-chain retinol dehydrogenase/reductase, is retinoic acid-inducible and frequently deleted in human neuroblastoma cell lines. (2002) (76)
- Combination of an Allosteric Akt Inhibitor MK-2206 with Etoposide or Rapamycin Enhances the Antitumor Growth Effect in Neuroblastoma (2012) (73)
- Induction of transforming growth factor beta 1 and its receptors during all-trans-retinoic acid (RA) treatment of RA-responsive human neuroblastoma cell lines. (1995) (72)
- Brain-derived neurotrophic factor protects neuroblastoma cells from vinblastine toxicity. (1996) (72)
- Potential Use of Imatinib in Ewing’s Sarcoma: Evidence for In Vitro and In Vivo Activity (2002) (70)
- Interferon γ Enhances the Effectiveness of Tumor Necrosis Factor-Related Apoptosis–Inducing Ligand Receptor Agonists in a Xenograft Model of Ewing’s Sarcoma (2004) (69)
- In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine. (2010) (68)
- Activation of Three Distinct RXR/RAR Heterodimers Induces Growth Arrest and Differentiation of Neuroblastoma Cells* (1997) (67)
- Retinoids and the control of growth/death decisions in human neuroblastoma cell lines (2004) (67)
- Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death (2007) (67)
- Genetic and pharmacologic identification of Akt as a mediator of brain-derived neurotrophic factor/TrkB rescue of neuroblastoma cells from chemotherapy-induced cell death. (2005) (66)
- NGF activation of TrkA induces vascular endothelial growth factor expression via induction of hypoxia-inducible factor-1α (2011) (64)
- Identification and Characterization of a Retinoic Acid-regulated Human Homologue of the unc-33-like Phosphoprotein Gene (hUlip) from Neuroblastoma Cells* (1997) (64)
- Regulation of N-myc expression is a critical event controlling the ability of human neuroblasts to differentiate. (1988) (63)
- Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma. (2017) (62)
- Selective Regulation of TrkA and TrkB Receptors by Retinoic Acid and Interferon-γ in Human Neuroblastoma Cell Lines (*) (1995) (61)
- Essential Role of the Zinc Finger Transcription Factor Casz1 for Mammalian Cardiac Morphogenesis and Development* (2014) (60)
- Molecular cloning and characterization of human Castor, a novel human gene upregulated during cell differentiation. (2006) (60)
- Molecular markers of neuroendocrine development and evidence of environmental regulation. (1987) (58)
- Inactivation of glycogen synthase kinase-3β contributes to brain-derived neutrophic factor/TrkB-induced resistance to chemotherapy in neuroblastoma cells (2007) (54)
- Inflammatory cytokines and HIV-1-associated neurodegeneration: oncostatin-M produced by mononuclear cells from HIV-1-infected individuals induces apoptosis of primary neurons. (1999) (54)
- TrkA Induces Apoptosis of Neuroblastoma Cells and Does So via a p53-dependent Mechanism*[boxs] (2005) (52)
- Activation of trk-A but not trk-B signal transduction pathway inhibits growth of neuroblastoma cells. (1997) (51)
- Neuropeptide Y expression in the developing adrenal gland and in childhood neuroblastoma tumors. (1990) (51)
- Ethanol inhibits brain-derived neurotrophic factor-mediated intracellular signaling and activator protein-1 activation in cerebellar granule neurons (2004) (48)
- Inhibition of STAT3 with the Generation 2.5 Antisense Oligonucleotide, AZD9150, Decreases Neuroblastoma Tumorigenicity and Increases Chemosensitivity (2016) (48)
- Increased N-myc expression following progressive growth of human neuroblastoma. (1986) (48)
- Perifosine‐induced inhibition of akt attenuates brain‐derived neurotrophic factor/TrkB‐induced chemoresistance in neuroblastoma in vivo (2011) (47)
- Biology of pediatric peripheral neuroectodermal tumors (1991) (47)
- Retinoic acid decreases targeting of p27 for degradation via an N-myc-dependent decrease in p27 phosphorylation and an N-myc-independent decrease in Skp2 (2003) (47)
- Targeting Akt to increase the sensitivity of neuroblastoma to chemotherapy: lessons learned from the brain-derived neurotrophic factor/TrkB signal transduction pathway (2007) (45)
- Potential use of imatinib in Ewing's Sarcoma: evidence for in vitro and in vivo activity. (2003) (45)
- HIV-1 infection of primary human neuroblasts. (1995) (43)
- Up-regulation of insulin-like growth factor-II expression is a feature of TrkA but not TrkB activation in SH-SY5Y neuroblastoma cells. (1999) (43)
- Identification, characterization, and biological activity of somatostatin receptors in human neuroblastoma cell lines. (1994) (43)
- Modulation of N-myc expression alters the invasiveness of neuroblastoma (1997) (42)
- Use of RNA interference to elucidate the effect of MYCN on cell cycle in neuroblastoma (2008) (41)
- PI3K and MAPK pathways mediate the BDNF/TrkB-increased metastasis in neuroblastoma (2016) (40)
- Interferon gamma enhances the effectiveness of tumor necrosis factor-related apoptosis-inducing ligand receptor agonists in a xenograft model of Ewing's sarcoma. (2004) (40)
- Cisplatin-induced cytotoxicity is blocked by brain-derived neurotrophic factor activation of TrkB signal transduction path in neuroblastoma. (2003) (40)
- CASZ1b, the Short Isoform of CASZ1 Gene, Coexpresses with CASZ1a during Neurogenesis and Suppresses Neuroblastoma Cell Growth (2011) (39)
- Fibroblast growth factor 2 induces differentiation and apoptosis of Askin tumour cells (2004) (38)
- Pediatric peripheral neuroectodermal tumors, oncogenes, and differentiation. (1990) (37)
- Expression of class I histocompatibility antigens in neuroectodermal tumors is independent of the expression of a transfected neuroblastoma myc gene. (1989) (35)
- Brain-derived neurotrophic factor modulates expression of chemokine receptors in the brain (2008) (33)
- MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma. (2016) (33)
- Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma (2015) (33)
- Antineoplastic effects of rosiglitazone and PPARγ transactivation in neuroblastoma cells (2006) (32)
- Collapsin response mediator proteins: Potential diagnostic and prognostic biomarkers in cancers (Review) (2014) (32)
- Targeting MYCN in Pediatric and Adult Cancers (2021) (32)
- Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells. (2010) (31)
- HIV-1 gene expression and replication in neuronal and glial cell lines with immature phenotype: effects of nerve growth factor. (1994) (31)
- Basic fibroblast growth factor supports human olfactory neurogenesis by autocrine/paracrine mechanisms (1998) (31)
- NGF activation of TrkA decreases N-myc expression via MAPK path leading to a decrease in neuroblastoma cell number (2004) (30)
- Interferon-γ–Dependent Infiltration of Human T Cells into Neuroblastoma Tumors In vivo (2009) (29)
- Peripheral neuroepithelioma: genetic analysis of tumor derived cell lines. (1985) (29)
- The production of a soluble human T-lymphocyte derived factor which substitutes for helper T lymphocytes in the in vitro production of immunoglobulin. (1979) (28)
- Multiple subsets of anti-tetanus toxoid antibody-producing cells in human peripheral blood differ by size, expression of membrane receptors, and mitogen reactivity. (1981) (28)
- The expression of multiple proto-oncogenes is differentially regulated during retinoic acid induced maturation of human neuroblastoma cell lines. (1988) (27)
- CASZ1 inhibits cell cycle progression in neuroblastoma by restoring pRb activity (2013) (27)
- Targeting Histone Deacetylase Activity to Arrest Cell Growth and Promote Neural Differentiation in Ewing Sarcoma (2018) (26)
- Pediatric cancer research: Surviving COVID‐19 (2020) (25)
- HIV-1 infection and the developing nervous system: lineage-specific regulation of viral gene expression and replication in distinct neuronal precursors. (1997) (25)
- Trk inhibitor attenuates the BDNF/TrkB-induced protection of neuroblastoma cells from etoposide in vitro and in vivo (2015) (25)
- Targeting the tumor necrosis factor-related apoptosis-inducing ligand path in neuroblastoma. (2003) (25)
- Structure and promoter analysis of the human unc-33-like phosphoprotein gene. E-box required for maximal expression in neuroblastoma and myoblasts. (2000) (24)
- CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG (2020) (24)
- The anti-tumor growth effect of a novel agent DMAMCL in rhabdomyosarcoma in vitro and in vivo (2019) (24)
- Characterization of Critical Domains within the Tumor Suppressor CASZ1 Required for Transcriptional Regulation and Growth Suppression (2012) (23)
- Glycogen synthase kinase 3 β ( GSK 3 β ) mediates 6-hydroxydopamine-induced neuronal death (2004) (22)
- Increased expression of p27Kip1 arrests neuroblastoma cell growth. (2001) (21)
- Targeting caspase 8 to reduce the formation of metastases in neuroblastoma (2006) (21)
- Cancer Stem Cells and Neuroblastoma: Characteristics and Therapeutic Targeting Options (2019) (20)
- Zinc finger transcription factor CASZ1 interacts with histones, DNA repair proteins and recruits NuRD complex to regulate gene transcription (2015) (20)
- Dihydropyrimidinase‐like protein 3 expression is negatively regulated by MYCN and associated with clinical outcome in neuroblastoma (2013) (19)
- Antibody potential of human peripheral blood lymphocytes differentially expressing surface membrane IgM. (1980) (19)
- Translocation of c-sis protooncogene in peripheral neuroepithelioma. (1987) (19)
- Pediatric pancreatoblastoma: histopathologic and cytogenetic characterization of tumor and derived cell line. (2005) (18)
- Lack of phospholipase A2 mutations in neuroblastoma, melanoma and colon‐cancer cell lines (1997) (18)
- Combination of Rapamycin and MK-2206 Induced Cell Death via Autophagy and Necroptosis in MYCN-Amplified Neuroblastoma Cell Lines (2020) (15)
- Differentiate or Die: the View from Montreal (2000) (15)
- Identification of Casz1 as a Regulatory Protein Controlling T Helper Cell Differentiation, Inflammation, and Immunity (2018) (15)
- Proteome and Acetylome Analysis Identifies Novel Pathways and Targets Regulated by Perifosine in Neuroblastoma (2017) (15)
- Single-cell detection of ets-1 transcripts in human neuroectodermal cells. (1991) (15)
- EZH 2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor Genes CASZ 1 , CLU , RUNX 3 , and NGFR (2011) (14)
- Novel Mutations in the p 16 / CDKN 2 A Binding Region of the Cyclin-dependent Kinase-4 Gene 1 (14)
- High-SETD8 inactivates p53 in neuroblastoma (2017) (13)
- Regulation of the in vitro monoclonal immunoglobulin production in cultures of peripheral blood mononuclear cells and bone marrow cells from myeloma patients mediated by T cell dependent mitogens. (1986) (13)
- ALK and MYCN: when two oncogenes are better than one. (2012) (12)
- Identification of CASZ1 nuclear export signal (NES) reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma (2016) (12)
- CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice (2021) (12)
- Neurotrophin Signaling in Cancer (2014) (11)
- New insights into the causes of cancer. (1991) (11)
- Matrix proteins induce neuroblastoma cell differentiation without altering cell growth. (1991) (10)
- New insight on the biology of neuroectodermal tumors. Workshop report from the University of Rome Tor Vergata and the IDI-IRCCS on the genetics and control of growth, differentiation, and programmed cell death. (1993) (10)
- Quantitative ubiquitylome analysis and crosstalk with proteome/acetylome analysis identified novel pathways and targets of perifosine treatment in neuroblastoma. (2018) (8)
- Combining selinexor with alisertib to target the p53 pathway in neuroblastoma (2022) (7)
- P53/PUMA are potential targets that mediate the protection of brain-derived neurotrophic factor (BDNF)/TrkB from etoposide-induced cell death in neuroblastoma (NB) (2018) (7)
- Novel agent DMAMCL suppresses osteosarcoma growth and decreases the stemness of osteosarcoma stem cell (2020) (7)
- HUlip, a human homologue of unc-33-like phosphoprotein of Caenorhabditis elegans; Immunohistochemical localization in the developing human brain and patterns of expression in nervous system tumors (2005) (7)
- Targeting the chromosomal passenger complex subunit INCENP induces polyploidization, apoptosis and senescence in neuroblastoma. (2019) (7)
- The Role of INI 1 and the SWI / SNF Complex in the Development of Rhabdoid Tumors : Meeting Summary from the Workshop on Childhood Atypical Teratoid / Rhabdoid Tumors 1 (2001) (6)
- Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma (2015) (6)
- Genetically InFormed Therapies—A “GIFT” for Children with Cancer (2012) (6)
- When LMO1 Meets MYCN, Neuroblastoma Is Metastatic. (2017) (5)
- Targeting a noncanonical, hairpin-containing G-quadruplex structure from the MYCN gene. (2021) (5)
- Unraveling the Enigmatic Origin of Neuroblastoma. (2020) (4)
- GENETIC ASPECTS OF IgD EXPRESSION: II. MULTIPLE FORMS OF δ CHAIN mRNA IN NORMAL MOUSE SPLEEN, MOUSE B‐CELL LYMPHOMAS AND MOUSE AND HUMAN MYELOMAS * (1982) (4)
- Patterns of regulation of nuclear proto-oncogenes MYCN and MYB in retinoic acid treated neuroblastoma cells. (1991) (4)
- Insulin-like growth factor-II expression is down-regulated in TrkA-transfected SK-N-AS neuroblastoma cells. (1999) (4)
- A Role for Differentiation Arrest in the Development of Neural Crest Tumors (1986) (4)
- Immunotherapy approaches targeting neuroblastoma (2020) (4)
- Structure and Promoter Analysis of the Humanunc-33-like Phosphoprotein Gene (2000) (4)
- Expression of surface membrane IgG on pokeweed mitogen-reactive anti-tetanus toxoid antibody-producing cells (1981) (3)
- Lineage specific transcription factor waves reprogram neuroblastoma from self-renewal to differentiation (2020) (3)
- BDNF/TrkB pathway upregulates PTHrP in neuroblastoma (2006) (3)
- Anti-GD2 antibodies conjugated to IL15 and IL21 mediate potent anti-tumor cytotoxicity against neuroblastoma. (2022) (3)
- Antitumor effects of the small molecule DMAMCL in neuroblastoma via suppressing aerobic glycolysis and targeting PFKL (2021) (3)
- Human IgA antibody and immunoglobulin production afterin vivo tetanus toxoid immunization: Size and surface membrane phenotype analysis (1982) (3)
- Developmentally regulated genes in neuroblastoma. (1988) (2)
- EZH2 Mediates Epigenetic Silencing of Neuroblastoma (2012) (2)
- Downregulation of ATXN3 Enhances the Sensitivity to AKT Inhibitors (Perifosine or MK-2206), but Decreases the Sensitivity to Chemotherapeutic Drugs (Etoposide or Cisplatin) in Neuroblastoma Cells (2021) (2)
- Differentiation and Retinoids (2005) (2)
- Abstract 4342: The allosteric Akt inhibitor MK-2206 inhibits neuroblastoma tumor cell growth in vitro and in vivo (2011) (1)
- Meeting report: death and differentiation in erice. (1994) (1)
- P53/PUMA are potential targets that mediate the protection of brain-derived neurotrophic factor (BDNF)/TrkB from etoposide-induced cell death in neuroblastoma (NB) (2018) (1)
- Preclinical testing of chimeric antigen receptor T cells in neuroblastoma mouse models (2021) (1)
- Abstract 5040: CASZ1 haploinsufficiency in murine embryonic stem cells causes increased MYC expression, aberrant lineage commitment, and prevents neurogenesis. (2013) (1)
- Development of a minimal residual disease assay for anaplastic lymphoma kinase mutations using digital droplet polymerase chain reaction (2018) (1)
- Genetic Evaluation of Ontologically Related Neural Crest Tumors (1989) (1)
- A “cooperative collaboration” between HAND2 and MYCN shapes neuroblastoma cell identity (2022) (1)
- Abstract 18962: The Epithelial-Mesenchymal Master Regulator Zeb1 Orchestrates the Cardiac Determinant Transcription Factor Castor Zinc Finger Protein 1 (casz1) Expression and Function in Heart Regeneration (2016) (1)
- Molecular Genetics of Neuroblastoma (2017) (1)
- Mouse IgD half molecules with shortened IgD heavy chain result from alterations within C delta locus. (1985) (1)
- Abstract 3872: Retinoic acid (RA) relieves EZH2-mediated epigenetic suppression in high-risk neuroblastoma (HR-NB) (2017) (1)
- Abstract 5447: Phosphorylation status of Ascl1 regulates neuroblastoma self-renewal and differentiation. (2013) (0)
- in Vitro and i n Vivo i nhibition of Neuroblastoma t umor c ell Growth by AK t i nhibitor Perifosine (2010) (0)
- Abstract 2537: Targeting chromosomal passenger complex by disruption of INCENP function inhibits tumor progression in neuroblastoma (2019) (0)
- Identification of a role for Casz1 in the control of T helper differentiation and inflammation (2017) (0)
- Abstract 5014: Identification and analysis of critical domains within the neuroblastoma tumor suppressor gene CASZ1 (2010) (0)
- Loss of PRC2 Enforces a Mesenchymal Neural Crest Stem Cell Phenotype in NF1-Deficient Cancer Through Activation of Core Transcription Factors (2021) (0)
- Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma (2023) (0)
- Castor Expression in Ocular Lens (2008) (0)
- Adenosine receptor lymphocytes in humoral immunodeficiency (1981) (0)
- Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor (2022) (0)
- Abstract 2630: Tumor suppressor CASZ1 inhibits normal myoblast and rhabdomyosarcoma (RMS) migration. (2013) (0)
- Hypoxia-Inducible Factor-1 Induces Vascular Endothelial Growth Factor Expression via Brain-Derived Neurotrophic Factor Activation of TrkB (2006) (0)
- Abstract 5248: Neuroblastoma tumors with different ALK mutations are sensitive to Perifosine (2010) (0)
- The sensitivity of TNF-related apoptosis-inducing ligand in neuroblastoma is increased by higher N-myc level but not blocked by BDNF/TrkB activation (2006) (0)
- Zinc finger transcription factor CASZ1b is involved in the DNA damage response in live cells. (2023) (0)
- Differentiation or Death: The View from Versailles (1998) (0)
- Mechanisms of Retinoid Inhibition of Cell Proliferation in Neuroblastoma (1999) (0)
- Molecular Genetics of Pediatric Solid Tumors: Basic Concepts and Recent Advances (1992) (0)
- Targeting Histone Deacetylase Activity to Arrest Cell Growth and Promote Neural Differentiation in Ewing Sarcoma (2018) (0)
- Abstract 3170: AKT/mTOR pharmacologic inhibition sensitizes RAS/MAPK-activated neuroblastoma cells to MEK1/2 inhibitors (2018) (0)
- Abstract A46: Charting the synthetic lethality landscape in pediatric cancer to advance whole-exome precision-based treatments (2020) (0)
- Cells from Vinblastine Toxicity Brain-derived Neurotrophic Factor Protects Neuroblastoma (2006) (0)
- Abstract 4880: CASZ1, a neuroblastoma tumor suppressor gene, is epigenetically silenced by EZH2 (2010) (0)
- Abstract 4736: Inhibition of STAT3 sensitizes neuroblastoma xenografts cells to Etoposide (2014) (0)
- Abstract 12: Metastatic neuroblastoma cancer stem cells display a mixed phenotype of tumor and niche origin required for survival (2010) (0)
- Corrigendum: Downregulation of ATXN3 enhances the sensitivity to AKT inhibitors (Perifosine or MK-2206), but decreases the sensitivity to chemotherapeutic drugs (etoposide or cisplatin) in neuroblastoma cells (2022) (0)
- Subject Index, Vol. 56, 1988 (1988) (0)
- Abstract 2115: CASZ1 suppresses neuroblastoma cell growth by restoring Rb activity in G1 and regulating kinases involved in G2/M progression (2011) (0)
- Abstract 2439: Inhibition of STAT3 with the generation 2.5 antisense oligonucleotide, AZD9150 increases the chemosensitivity and decreases tumor-initiating potential of neuroblastoma cells (2016) (0)
- Antitumor effects of the small molecule DMAMCL in neuroblastoma via suppressing aerobic glycolysis and targeting PFKL (2021) (0)
- Loss of CASZ1 tumor suppressor linked to oncogenic subversion of neuroblastoma core regulatory circuitry (2022) (0)
- Abstract 5522: Novel myogenic differentiation transcription factor CASZ1 suppresses rhabdomyosarcoma tumor growth (2017) (0)
- NGFR , and RUNX 3 , CLU , CASZ 1 Genes EZH 2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor (2011) (0)
- HAND2 assists MYCN enhancer invasion to regulate a noradrenergic neuroblastoma phenotype. (2023) (0)
- - Kinase Pathway ′ via Phosphatidylinositol 3 Neuroblastoma Cells from Chemotherapy-induced Apoptosis Brain-derived Neurotrophic Factor Activation of TrkB Protects (2002) (0)
- Abstract 5015: Hcasz5, CASZ1 gene transcript variant 2 with 5 zinc fingers functions as a tumor suppressor in Neuroblastoma (2010) (0)
- Preface: The Status of Pediatric Solid Tumors in 2015. (2015) (0)
- Abstract 3161: Massively parallel transcriptome sequencing in neuroblastoma reveals specific mRNA splicing patterns controlled by RNA binding splicing factors. (2013) (0)
- Abstract 1440: Validation of potential therapeutic targeting of IL-6/JAK/STAT3 pathway by AZD1480 in neuroblastoma and other pediatric tumors (2012) (0)
- Abstract B42: Mutant RAS represses CASZ1, a novel regulator of MYOD and MYOG, to inhibit embryonal rhabdomyosarcoma differentiation (2020) (0)
- CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG (2020) (0)
- Abstract 3898: Loss of polycomb repressive complex 2 activates HOXB8 and remodels super enhancers in malignant peripheral nerve sheath tumors (2020) (0)
- The anti-tumor growth effect of a novel agent DMAMCL in rhabdomyosarcoma in vitro and in vivo (2019) (0)
- Contents, Vol. 56, 1988 (1988) (0)
- Abstract 3867: Epigenetic siRNA and chemical screens identify SETD8 inhibition as a therapeutic strategy to reactivate p53 in high-risk neuroblastoma (2017) (0)
- Abstract P164: Identification of the p53 negative feedback loop as a target for enhancing selinexor activity in neuroblastoma (2021) (0)
- Abstract 487: Whole genome screen to identify genes targeting MYCN-driven embryonal tumors (2015) (0)
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