Carol Tamminga
American psychiatrist and neuroscientist
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(Suggest an Edit or Addition)According to Wikipedia, Carol A. Tamminga is an American psychiatrist and neuroscientist, focusing in treating psychotic illnesses, such as schizophrenia, psychotic bipolar disorder, and schizoaffective disorder, currently the Lou and Ellen McGinley Distinguished Chair in Psychiatric Research and the Chief of the Translational Neuroscience Division in Schizophrenia at University of Texas Southwestern Medical Center. She has been Chair of the Department of Psychiatry at UTSW since 2008. She is an Elected Fellow of the National Academy of Medicine. She serves on the advisory boards of the Brain and Behavioral Research Foundation and of the National Institute of Mental Health . In 2011 she was awarded the Lieber Prize for Outstanding Achievement in Schizophrenia Research. Tamminga led a study examining whether giving Prozac to fetuses with Down syndrome would improve the functioning of their brains. In her attempt to confirm psychiatric diagnoses biologically, she found "biotypes" or "clusters." Her current research involves mechanisms underlying schizophrenia, especially its most prominent symptoms, psychosis and memory dysfunction.
Carol Tamminga's Published Works
Published Works
- Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions (2007) (1824)
- Positron emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics. (1986) (922)
- Subanesthetic Doses of Ketamine Stimulate Psychosis in Schizophrenia (1995) (901)
- Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. (2003) (794)
- Effects of Ketamine in Normal and Schizophrenic Volunteers (2001) (625)
- Antidepressant Actions of Histone Deacetylase Inhibitors (2009) (547)
- Limbic system abnormalities identified in schizophrenia using positron emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome. (1992) (542)
- Increased cortical kynurenate content in schizophrenia (2001) (540)
- Antidepressant Effect of Optogenetic Stimulation of the Medial Prefrontal Cortex (2010) (539)
- The hippocampal formation in schizophrenia. (2010) (512)
- Social stress induces neurovascular pathology promoting depression (2017) (493)
- ΔFosB in brain reward circuits mediates resilience to stress and antidepressant responses (2010) (457)
- Ketamine activates psychosis and alters limbic blood flow in schizophrenia (1995) (440)
- Sex-specific transcriptional signatures in human depression (2017) (427)
- Identification of Distinct Psychosis Biotypes Using Brain-Based Biomarkers. (2016) (404)
- Schizophrenia and glutamatergic transmission. (1998) (393)
- Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. (2000) (376)
- Human postmortem tissue: What quality markers matter? (2006) (335)
- Neuropsychological impairments in schizophrenia and psychotic bipolar disorder: findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study. (2013) (318)
- Controlled, dose-response study of sertindole and haloperidol in the treatment of schizophrenia. Sertindole Study Group. (1997) (310)
- Reduced activation and expression of ERK1/2 MAP kinase in the post‐mortem brain of depressed suicide subjects (2001) (301)
- Gender and schizophrenia. (1997) (295)
- Higher expression of serotonin 5-HT(2A) receptors in the postmortem brains of teenage suicide victims. (2002) (267)
- Clinical phenotypes of psychosis in the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP). (2013) (266)
- A Role for Repressive Histone Methylation in Cocaine-Induced Vulnerability to Stress (2011) (252)
- Phenotype of schizophrenia: a review and formulation (2005) (251)
- Probing the human hippocampus using rCBF: Contrasts in schizophrenia (2001) (239)
- Differences in Resting-State Functional Magnetic Resonance Imaging Functional Network Connectivity Between Schizophrenia and Psychotic Bipolar Probands and Their Unaffected First-Degree Relatives (2012) (239)
- The initial field trials of DSM-5: new blooms and old thorns. (2013) (231)
- 2016 in Review. (2016) (222)
- Functional sites of neuroleptic drug action in the human brain: PET/FDG studies with and without haloperidol. (1996) (222)
- Schizophrenic symptoms improve with apomorphine. (1978) (222)
- Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression (2013) (218)
- Critical Role of Histone Turnover in Neuronal Transcription and Plasticity (2015) (217)
- Olanzapine compared with chlorpromazine in treatment-resistant schizophrenia. (1998) (210)
- Is Aberrant Functional Connectivity A Psychosis Endophenotype? A Resting State Functional Magnetic Resonance Imaging Study (2013) (201)
- Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia (2014) (200)
- Schizophrenia: Scientific Progress (1989) (197)
- Identification of Distinct Psychosis Biotypes Using Brain-Based Biomarkers. (2018) (193)
- Practice guideline for the treatment of patients with substance use disorders: alcohol, cocaine, opioids. American Psychiatric Association. (1995) (190)
- Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors (2014) (184)
- A dimensional approach to the psychosis spectrum between bipolar disorder and schizophrenia: The Schizo-Bipolar Scale (2011) (182)
- Abnormal expression and functional characteristics of cyclic adenosine monophosphate response element binding protein in postmortem brain of suicide subjects. (2003) (174)
- β-catenin mediates behavioral resilience through Dicer1/microRNA regulation (2014) (167)
- Medial temporal lobe structures and hippocampal subfields in psychotic disorders: findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study. (2014) (166)
- AKT Signaling within the Ventral Tegmental Area Regulates Cellular and Behavioral Responses to Stressful Stimuli (2008) (165)
- Diffusion tensor imaging white matter endophenotypes in patients with schizophrenia or psychotic bipolar disorder and their relatives. (2013) (164)
- Clozapine in tardive dyskinesia: observations from human and animal model studies. (1994) (163)
- A Novel Role of the WNT-Dishevelled-GSK3β Signaling Cascade in the Mouse Nucleus Accumbens in a Social Defeat Model of Depression (2011) (161)
- Patient response and resource management: another view of clozapine treatment of schizophrenia. (1995) (161)
- Insight and frontal cortical function in schizophrenia: A review (2006) (153)
- Long‐term Psychiatric Outcomes Following Traumatic Brain Injury: A Review of the Literature (2009) (151)
- The neurobiology of cognition in schizophrenia. (2006) (150)
- Strong inference, theory testing, and the neuroanatomy of schizophrenia. (1993) (148)
- The role of negative symptoms and cognitive dysfunction in schizophrenia outcome (1998) (145)
- Sequential Regional Cerebral Blood Flow Brain Scans Using PET with H215O Demonstrate Ketamine Actions in CNS Dynamically (2001) (144)
- Clonazepam treatment of tardive dyskinesia: a practical GABAmimetic strategy. (1990) (143)
- Gray matter volume as an intermediate phenotype for psychosis: Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP). (2013) (142)
- Expression of acidic and basic fibroblast growth factors in the substantia nigra of rat, monkey, and human. (1991) (141)
- Genetics and intermediate phenotypes of the schizophrenia—bipolar disorder boundary (2010) (139)
- Bipolar and schizophrenia network for intermediate phenotypes: outcomes across the psychosis continuum. (2014) (135)
- Partial dopamine agonists in the treatment of psychosis (2002) (134)
- Chromatin alterations associated with down-regulated metabolic gene expression in the prefrontal cortex of subjects with schizophrenia. (2005) (133)
- Molecular adaptations of the blood–brain barrier promote stress resilience vs. depression (2020) (132)
- Correlations Between rCBF and Symptoms in Two Independent Cohorts of Drug-Free Patients with Schizophrenia (2006) (132)
- Functional effects of antipsychotic drugs: comparing clozapine with haloperidol (2003) (126)
- Glutamatergic aspects of schizophrenia (1999) (123)
- Reversal of Depressed Behaviors in Mice by p11 Gene Therapy in the Nucleus Accumbens (2010) (122)
- Improvement in tardive dyskinesia after muscimol therapy. (1979) (120)
- Partial dopamine agonists and dopaminergic stabilizers, in the treatment of psychosis. (2002) (117)
- Brain Structure Biomarkers in the Psychosis Biotypes: Findings From the Bipolar-Schizophrenia Network for Intermediate Phenotypes (2017) (114)
- Muscimol: GABA agonist therapy in schizophrenia. (1978) (113)
- D2-Family receptor distribution in human postmortem tissue: an autoradiographic study (1995) (111)
- Treatment-resistant schizophrenic patients respond to clozapine after olanzapine non-response (1999) (111)
- Resting-state brain function in schizophrenia and psychotic bipolar probands and their first-degree relatives (2014) (110)
- Glutamate dysfunction in hippocampus: relevance of dentate gyrus and CA3 signaling. (2012) (110)
- Are structural brain abnormalities associated with suicidal behavior in patients with psychotic disorders? (2013) (106)
- Cerebrospinal fluid levels of quinolinic acid in Huntington's disease and schizophrenia (1988) (106)
- Striatal enlargement in rats chronically treated with neuroleptic (1998) (104)
- Effects of Noncompetitive NMDA Receptor Blockade on Anterior Cingulate Cerebral Blood Flow in Volunteers with Schizophrenia (2005) (104)
- Time to clozapine response in a standardized trial. (1997) (103)
- Modulation of limbic circuitry predicts treatment response to antipsychotic medication: a functional imaging study in schizophrenia (2009) (102)
- Abnormal patterns of regional cerebral blood flow in schizophrenia with primary negative symptoms during an effortful auditory recognition task. (2001) (102)
- Persistent β2*-nicotinic acetylcholinergic receptor dysfunction in major depressive disorder. (2012) (100)
- Increased saccadic distractibility in tardive dyskinesia: Functional evidence for subcortical GABA dysfunction (1989) (100)
- Antipsychotic Properties of the Partial Dopamine Agonist (−)-3-(3-Hydroxyphenyl)-N-n-Propylpiperidine (Preclamol) in Schizophrenia (1998) (99)
- The limbic cortex in schizophrenia: focus on the anterior cingulate (2000) (96)
- Brain activity in adolescent major depressive disorder before and after fluoxetine treatment. (2012) (96)
- Postsynaptic supersensitivity in schizophrenia. (1977) (95)
- Direct determination of dopamine D4 receptors in normal and schizophrenic postmortem brain tissue: a [3H]NGD-94-1 study (1998) (95)
- Transdiagnostic Associations Between Functional Brain Network Integrity and Cognition (2017) (95)
- Brain gamma-aminobutyric acid abnormality in tardive dyskinesia. Reduction in cerebrospinal fluid GABA levels and therapeutic response to GABA agonist treatment. (1987) (94)
- Correlations between brain structure and symptom dimensions of psychosis in schizophrenia, schizoaffective, and psychotic bipolar I disorders. (2015) (94)
- Differential expression of metabotropic glutamate receptors 2 and 3 in schizophrenia: a mechanism for antipsychotic drug action? (2009) (93)
- Placebo-controlled study of the D4/5-HT2A antagonist fananserin in the treatment of schizophrenia. (1999) (92)
- Developing novel treatments for mood disorders: accelerating discovery (2002) (92)
- Resting State Electroencephalogram Oscillatory Abnormalities in Schizophrenia and Psychotic Bipolar Patients and Their Relatives from the Bipolar and Schizophrenia Network on Intermediate Phenotypes Study (2014) (92)
- Phenomenological Psychopathology and Schizophrenia: Contemporary Approaches and Misunderstandings (2011) (92)
- Regional alterations in RGS4 protein in schizophrenia (2006) (91)
- Hippocampal volume is reduced in schizophrenia and schizoaffective disorder but not in psychotic bipolar I disorder demonstrated by both manual tracing and automated parcellation (FreeSurfer). (2015) (90)
- Fluoxetine Epigenetically Alters the CaMKIIα Promoter in Nucleus Accumbens to Regulate ΔFosB Binding and Antidepressant Effects (2014) (90)
- Frequency-Specific Neural Signatures of Spontaneous Low-Frequency Resting State Fluctuations in Psychosis: Evidence From Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) Consortium. (2015) (89)
- Cholecystokinin-octapeptide effects on conditioned-avoidance behavior, stereotypy and catalepsy. (1982) (89)
- 2017 in Review. (2017) (89)
- Oculomotor abnormalities and their clinical correlates in schizophrenia. (1989) (88)
- Ultrastructural correlates of haloperidol‐induced oral dyskinesias in rat striatum (1995) (88)
- Alzheimer's disease (1987) (88)
- VGF function in depression and antidepressant efficacy (2017) (87)
- Effects of dopamine agonists in tardive dyskinesia. (1977) (86)
- Loss of pattern separation performance in schizophrenia suggests dentate gyrus dysfunction (2014) (86)
- Identifying dynamic functional connectivity biomarkers using GIG‐ICA: Application to schizophrenia, schizoaffective disorder, and psychotic bipolar disorder (2017) (84)
- Induction of Activating Transcription Factors (ATFs) ATF2, ATF3, and ATF4 in the Nucleus Accumbens and Their Regulation of Emotional Behavior (2008) (84)
- 2018 in Review. (2018) (84)
- White matter abnormalities across the lifespan of schizophrenia: a harmonized multi-site diffusion MRI study (2019) (83)
- Reduced levels of vasopressin and reduced behavioral modulation of oxytocin in psychotic disorders. (2014) (82)
- Cholinergic influences in tardive dyskinesia. (1977) (81)
- Clozapine but not Haloperidol Re-establishes Normal Task-Activated rCBF Patterns in Schizophrenia within the Anterior Cingulate Cortex (2004) (81)
- Serum Response Factor Promotes Resilience to Chronic Social Stress through the Induction of ΔFosB (2010) (80)
- Schizophrenia: moving beyond monoamine antagonists. (2008) (80)
- [(3)H]cAMP binding sites and protein kinase a activity in the prefrontal cortex of suicide victims. (2002) (79)
- Transdiagnostic dimensions of psychosis in the Bipolar‐Schizophrenia Network on Intermediate Phenotypes (B‐SNIP) (2019) (79)
- Elevated antisaccade error rate as an intermediate phenotype for psychosis across diagnostic categories. (2014) (78)
- Dopamine D3 receptor gene: organization, transcript variants, and polymorphism associated with schizophrenia. (1996) (78)
- A neuroendocrine study of supersensitivity in tardive dyskinesia. (1977) (77)
- Differential olanzapine plasma concentrations by sex in a fixed-dose study (1999) (77)
- Ketamine Effects on Eye Movements (2000) (76)
- Regional expression of RGS4 mRNA in human brain † (2004) (75)
- The GABAB receptor as a target for antidepressant drug action (2011) (75)
- Protein kinase C in the postmortem brain of teenage suicide victims (1997) (75)
- Emotion recognition deficits in schizophrenia-spectrum disorders and psychotic bipolar disorder: Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study (2014) (74)
- Prefrontal brain network connectivity indicates degree of both schizophrenia risk and cognitive dysfunction. (2013) (74)
- Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression (2020) (73)
- Conserved Higher-Order Chromatin Regulates NMDA Receptor Gene Expression and Cognition (2014) (73)
- Cerebral blood flow relationships associated with a difficult tone recognition task in trained normal volunteers. (1998) (73)
- Pathological gambling: focusing on the addiction, not the activity. (2006) (73)
- Glutamate pharmacology and the treatment of schizophrenia: current status and future directions (1995) (72)
- Neurobiological underpinnings of insight deficits in schizophrenia (2007) (71)
- Alterations in hippocampal connectivity across the psychosis dimension (2015) (71)
- ACF chromatin remodeling complex mediates stress–induced depressive–like behavior (2015) (70)
- Reimagining psychoses: An agnostic approach to diagnosis (2013) (70)
- Local Gyrification Index in Probands with Psychotic Disorders and Their First-Degree Relatives (2014) (69)
- The Effect of Chronic Haloperidol Treatment on Dendritic Spines in the Rat Striatum (1997) (68)
- Divalproex ER Combined with Olanzapine or Risperidone for Treatment of Acute Exacerbations of Schizophrenia (2009) (68)
- The efficacy of high-dose olanzapine versus clozapine in treatment-resistant schizophrenia: a double-blind crossover study. (2003) (68)
- Functional effects of single dose first- and second-generation antipsychotic administration in subjects with schizophrenia (2005) (67)
- Behavioral, physiological, and neuroendocrine responses to arecoline in normal twins and “well state” bipolar patients (1983) (67)
- Delayed regional metabolic actions of phencyclidine. (1993) (67)
- Regulator of G protein signaling 4 is a crucial modulator of antidepressant drug action in depression and neuropathic pain models (2013) (67)
- Magnetic resonance spectroscopy and tissue protein concentrations together suggest lower glutamate signaling in dentate gyrus in schizophrenia (2014) (66)
- Synaptic proteins in the hippocampus indicative of increased neuronal activity in CA3 in schizophrenia. (2015) (66)
- Event-Related Potential and Time-Frequency Endophenotypes for Schizophrenia and Psychotic Bipolar Disorder (2015) (66)
- Cognitive burden of anticholinergic medications in psychotic disorders (2017) (66)
- Phencyclidine (PCP) and dizocilpine (MK801) exert time‐dependent effects on the expression of immediate early genes in rat brain (1998) (66)
- DEPRESSION ASSOCIATED WITH ORAL CHOLINE (1976) (65)
- Dopamine agonist treatment of schizophrenia with N-propylnorapomorphine. (1986) (64)
- Schizophrenia: treatment targets beyond monoamine systems. (2011) (62)
- Basal Ganglia GABAA and Dopamine D1 Binding Site Correlates of Haloperidol-Induced Oral Dyskinesias in Rat (1994) (62)
- Effect of dopamine system activation on substantia nigra pars reticulata output neurons: variable single-unit responses in normal rats and inhibition in 6-hydroxydopamine-lesioned rats (1984) (61)
- Kv3.1-containing K+ channels are reduced in untreated schizophrenia and normalized with antipsychotic drugs (2014) (61)
- Neural Activations During Auditory Oddball Processing Discriminating Schizophrenia and Psychotic Bipolar Disorder (2012) (60)
- Brain activation patterns in schizophrenic and comparison volunteers during a matched-performance auditory recognition task. (2000) (60)
- Amygdala Hyperactivity at Rest in Paranoid Individuals With Schizophrenia. (2015) (60)
- ITI-007 for the Treatment of Schizophrenia: A 4-Week Randomized, Double-Blind, Controlled Trial (2016) (59)
- mRNA and Protein Expression of Selective Alpha Subunits of G Proteins are Abnormal in Prefrontal Cortex of Suicide Victims (2002) (59)
- Effects of lithium on cortical thickness and hippocampal subfield volumes in psychotic bipolar disorder. (2015) (59)
- Evaluating Glutamatergic Transmission in Schizophrenia (2003) (58)
- Measurement and treatment research to improve cognition in schizophrenia: neuropharmacological aspects (2004) (58)
- Effects of ketamine on leading saccades during smooth-pursuit eye movements may implicate cerebellar dysfunction in schizophrenia. (2002) (58)
- Tone discrimination performance in schizophrenic patients and normal volunteers: impact of stimulus presentation levels and frequency differences (1995) (58)
- Sex and diagnosis specific associations between DNA methylation of the oxytocin receptor gene with emotion processing and temporal-limbic and prefrontal brain volumes in psychotic disorders. (2016) (57)
- An important role for Cholecystokinin, a CLOCK target gene, in the development and treatment of manic-like behaviors (2013) (57)
- Neuroleptic-induced vacuous chewing movements as an animal model of tardive dyskinesia: a study in three rat strains (2005) (56)
- Phosphorylation of the tubulin‐binding protein, stathmin, by Cdk5 and MAP kinases in the brain (2006) (55)
- Comparing genes and phenomenology in the major psychoses: schizophrenia and bipolar 1 disorder. (2007) (55)
- Strategies for Advancing Disease Definition Using Biomarkers and Genetics: The Bipolar and Schizophrenia Network for Intermediate Phenotypes. (2017) (54)
- Cognitive endophenotypes of psychosis within dimension and diagnosis (2012) (54)
- Stimulation of Prolactin and Growth Hormone Secretion by Muscimol, a γ-Aminobutyric Acid Agonist (1978) (53)
- Functional Connectivity of Brain Structures Correlates with Treatment Outcome in Major Depressive Disorder (2011) (53)
- Brain gray matter phenotypes across the psychosis dimension (2012) (53)
- Behavioral response inhibition in psychotic disorders: Diagnostic specificity, familiality and relation to generalized cognitive deficit (2014) (52)
- Deficits in Syntaxin 1 Phosphorylation in Schizophrenia Prefrontal Cortex (2010) (52)
- Traditional and new antipsychotic drugs differentially alter neurotransmission markers in basal ganglia‐thalamocortical neural pathways (2001) (52)
- PCP‐induced alterations in cerebral glucose utilization in rat brain: Blockade by metaphit, a PCP‐receptor‐acylating agent (1987) (50)
- Des-tyrosine-γ-endorphin administration in chronic schizophrenics. A preliminary report (1981) (50)
- Association of Choroid Plexus Enlargement With Cognitive, Inflammatory, and Structural Phenotypes Across the Psychosis Spectrum. (2019) (50)
- The Maryland Psychiatric Research Center scale and the characterization of involuntary movements (1997) (50)
- Hippocampal function, declarative memory, and schizophrenia: Anatomic and functional neuroimaging considerations (2005) (50)
- Frontal cortex function. (2004) (49)
- Abnormal smooth pursuit eye movements in schizophrenic patients are associated with cerebral glucose metabolism in oculomotor regions (1995) (49)
- Benzodiazepine receptors in the post-mortem brain of suicide victims and schizophrenic subjects (1997) (49)
- Positron emission tomographic studies of regional cerebral glucose metabolism in idiopathic dystonia. (1988) (48)
- Spatiotemporal and frequency domain analysis of auditory paired stimuli processing in schizophrenia and bipolar disorder with psychosis. (2012) (48)
- Pursuit eye movements as an intermediate phenotype across psychotic disorders: Evidence from the B-SNIP study (2015) (48)
- Entorhinal cortex in temporal lobe epilepsy. (1995) (48)
- Multivariate Relationships Between Peripheral Inflammatory Marker Subtypes and Cognitive and Brain Structural Measures in Psychosis (2020) (47)
- Images in neuroscience (2004) (47)
- Muscarinic Agonists for the Treatment of Cognition in Schizophrenia (2008) (47)
- The relationship between affective state and the rhythmicity of activity in bipolar disorder. (2014) (47)
- Adverse Effects and Laboratory Parameters of High-Dose Olanzapine vs. Clozapine in Treatment-Resistant Schizophrenia (2003) (46)
- Efficacy and Safety of Lumateperone for Treatment of Schizophrenia (2020) (46)
- D2-type dopamine receptors in postmortem human brain sections from normal and schizophrenic subjects. (1996) (46)
- Serotonin and schizophrenia. (1998) (46)
- The neurobiology of cognition in schizophrenia. (2006) (45)
- Brain choline acetyltransferase activity and neuropeptide Y concentrations in Alzheimer's disease (1986) (45)
- Long-term outcome of patients who receive ketamine during research (2001) (44)
- GABA-agonist therapy for Alzheimer's disease. (1986) (44)
- Epigenetic regulation of synaptic remodeling in stress disorders (2013) (44)
- Low phosphoinositide-specific phospholipase C activity and expression of phospholipase C beta1 protein in the prefrontal cortex of teenage suicide subjects. (1999) (44)
- Social memory in mice: Disruption with an NMDA antagonist and attenuation with antipsychotic drugs (2009) (43)
- Racial disparities in bipolar disorder treatment and research: a call to action (2018) (43)
- GABA AGONIST TREATMENT IMPROVES TARDIVE DYSKINESIA (1983) (42)
- Co-administration of progabide inhibits haloperidol-induced oral dyskinesias in rats. (1992) (42)
- Lysine vasopressin in Alzheimer disease (1982) (42)
- Neurobiology of self-awareness in schizophrenia: An fMRI study (2012) (42)
- Neuroplasticity and schizophrenia (2004) (42)
- Polygenic risk for schizophrenia and measured domains of cognition in individuals with psychosis and controls (2018) (42)
- Deconstructing psychosis. (2007) (41)
- Cell type-specific epigenetic links to schizophrenia risk in the brain (2019) (41)
- 2015 in Review. (2015) (41)
- Sertindole in the treatment of psychosis in schizophrenia: efficacy and safety (1997) (40)
- Neural complexity as a potential translational biomarker for psychosis. (2017) (39)
- Effects of the D3 and autoreceptor-preferring dopamine antagonist (+)-UH232 in schizophrenia (1998) (38)
- Smooth pursuit eye movement, prepulse inhibition, and auditory paired stimuli processing endophenotypes across the schizophrenia-bipolar disorder psychosis dimension. (2014) (38)
- Altered expression and phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) in postmortem brain of suicide victims with or without depression. (2003) (38)
- Treating impaired cognition in schizophrenia. (2012) (37)
- Does Biology Transcend the Symptom-based Boundaries of Psychosis? (2016) (37)
- Localization of NAAG-related gene expression deficits to the anterior hippocampus in schizophrenia (2009) (37)
- Diverse Non-genetic, Allele-Specific Expression Effects Shape Genetic Architecture at the Cellular Level in the Mammalian Brain (2017) (36)
- THIP treatment of Huntington's disease (1983) (36)
- Impulsivity across the psychosis spectrum: Correlates of cortical volume, suicidal history, and social and global function (2016) (36)
- Comparison of objective and subjective assessments of sleep time in subjects with bipolar disorder. (2013) (36)
- Dr. Pandey and Associates Reply (1977) (36)
- Sleep polygraphy in schizophrenia: Methodological issues (1990) (35)
- Cholecystokinin-octapeptide fragments: binding to brain cholecystokinin receptors. (1984) (35)
- Regression dynamic causal modeling for resting‐state fMRI (2020) (34)
- Unitary construct of generalized cognitive ability underlying BACS performance across psychotic disorders and in their first-degree relatives (2016) (34)
- Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior (2016) (34)
- Learning and Generalization in Schizophrenia: Effects of Disease and Antipsychotic Drug Treatment (2010) (34)
- Changes in psychopathology and dyskinesia after neuroleptic withdrawal in a double-blind design (1993) (33)
- [3H]Neurotensin receptor densities in human postmortem brain tissue obtained from normal and schizophrenic persons. An autoradiographic study (1998) (33)
- Dr. Tamminga and Associates Reply (1978) (33)
- Mixture in the distribution of haloperidol-induced oral dyskinesias in the rat supports an animal model of tardive dyskinesia (1998) (33)
- VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine (2018) (32)
- In vivo detection of serine in the human brain by proton magnetic resonance spectroscopy (1H‐MRS) at 7 Tesla (2009) (32)
- NMDA-Sensitive Glutamate Antagonism: A Human Model for Psychosis (1999) (32)
- Auditory steady-state EEG response across the schizo-bipolar spectrum (2019) (32)
- Chronic Olanzapine or Sertindole Treatment Results in Reduced Oral Chewing Movements in Rats Compared to Haloperidol (1998) (32)
- Absence of ketamine effects on memory and other cognitive functions in schizophrenia patients. (1996) (31)
- Hippocampal Volume in Healthy Controls Given 3-Day Stress Doses of Hydrocortisone (2015) (31)
- The interactive effects of ketamine and nicotine on human cerebral blood flow (2010) (30)
- Psychiatric morbidity in research volunteers. (1990) (30)
- Huntington's disease (1986) (30)
- Increased cardiometabolic dysfunction in first-degree relatives of patients with psychotic disorders (2015) (30)
- The promise of new drugs for schizophrenia treatment. (1997) (29)
- Diagnostic specificity and familiality of early versus late evoked potentials to auditory paired stimuli across the schizophrenia-bipolar psychosis spectrum. (2014) (29)
- Schizophrenia: new phenes and new genes. (1999) (29)
- Novel transcriptional networks regulated by CLOCK in human neurons (2017) (29)
- Callosal Abnormalities Across the Psychosis Dimension: Bipolar Schizophrenia Network on Intermediate Phenotypes (2016) (29)
- Multivariate genetic determinants of EEG oscillations in schizophrenia and psychotic bipolar disorder from the BSNIP study (2015) (29)
- The Wechsler ACS Social Perception Subtest (2012) (29)
- Welcome (2018) (28)
- Accelerated evolution of oligodendrocytes in the human brain (2019) (28)
- Impaired Context Processing is Attributable to Global Neuropsychological Impairment in Schizophrenia and Psychotic Bipolar Disorder (2016) (28)
- Cognitive Function in Individuals With Psychosis: Moderation by Adolescent Cannabis Use. (2016) (28)
- Testing Psychosis Phenotypes From Bipolar-Schizophrenia Network for Intermediate Phenotypes for Clinical Application: Biotype Characteristics and Targets. (2020) (28)
- The new generation of antipsychotic drugs (1996) (28)
- Alterations in sleep polygraphy after neuroleptic withdrawal: A putative supersensitive dopaminergic mechanism (1989) (27)
- Separate mechanisms for behavioral, cardiovascular, and hormonal responses to dextroamphetamine in man (2004) (27)
- The Promise of New Drugs for Schizophrenia Treatment (1997) (27)
- Hippocampal novelty activations in schizophrenia: Disease and medication effects (2012) (27)
- The neuropharmacology of psychosis. (2007) (27)
- Risk factors for schizophrenia. Follow-up data from the Northern Finland 1966 Birth Cohort Study. (2006) (27)
- Shared Genetic Risk of Schizophrenia and Gray Matter Reduction in 6p22.1 (2017) (27)
- Negative Symptoms: A Critique of Current Approaches (1991) (26)
- An increase in NMDA-sensitive [3H]glutamate and [3H]kainate binding in hippocampus 24 hours after PCP (1994) (26)
- Increased Protein Insolubility in Brains From a Subset of Patients With Schizophrenia. (2019) (26)
- Characterizing functional regional homogeneity (ReHo) as a B-SNIP psychosis biomarker using traditional and machine learning approaches (2020) (26)
- CHOLECYSTOKININ: POTENTIAL PEPTIDERGIC ANTIPSYCHOTIC (1984) (26)
- Examining Functional Resting-State Connectivity in Psychosis and Its Subgroups in the Bipolar-Schizophrenia Network on Intermediate Phenotypes Cohort. (2016) (26)
- CCK26–33 Degrading Activity in Brain and Nonneural Tissue: A Metalloendopeptidase (1985) (25)
- Reduced brain somatostatin levels in Alzheimer's disease. (1985) (25)
- Vasopressin studies in Alzheimer's disease (1982) (25)
- Sex differences in associations of arginine vasopressin and oxytocin with resting‐state functional brain connectivity (2017) (25)
- Brain gray matter network organization in psychotic disorders (2019) (25)
- Bromocriptine and CF 25-397 in the treatment of tardive dyskinesia. (1980) (24)
- Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study (2017) (23)
- 2011 in Review (2011) (23)
- Working memory impairment in probands with schizoaffective disorder and first degree relatives of schizophrenia probands extend beyond deficits predicted by generalized neuropsychological impairment (2015) (23)
- Pharmacologic properties of (−)-3PPP (preclamol) in man (2005) (23)
- Cooperative synaptic and intrinsic plasticity in a disynaptic limbic circuit drive stress-induced anhedonia and passive coping in mice (2020) (23)
- Retinal layer abnormalities and their association with clinical and brain measures in psychotic disorders: A preliminary study (2020) (23)
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- 92. Peripheral Oxytocin and Vasopressin Modulates Regional Brain Activity Differently in Men and Women With Schizophrenia (2017) (0)
- White matter abnormalities in persons with schizophrenia and psychotic bipolar disorder and their relatives (2011) (0)
- S.11.04 Are endophenotypes a useful concept? (2015) (0)
- Brief Report: Insight into Illness and Social Attributional Style in Asperger’s Syndrome (2012) (0)
- C.06.02 Predictors of individual response and long-term compliance in schizophrenia treatment (2007) (0)
- 197. Inflammatory Differences in Multilayer Functional Network Topology Impacts Cognition in Psychosis (2023) (0)
- T22. PITUITARY GLAND VOLUME DIFFERENCES IN INDIVIDUALS WITH PSYCHOSIS: RESULTS FROM THE BIPOLAR-SCHIZOPHRENIA NETWORK ON INTERMEDIATE PHENOTYPES (B-SNIP) STUDY (2018) (0)
- Novel Allele‐Specific Epigenetic Effects Shape Genetic Architecture in the Brain (2017) (0)
- rCBF pattern differences in trained normal volunteers and schizophrenic patients performing effortful tone recognition tasks (1995) (0)
- Oculomotor studies in schizophrenic patients with and without tardive dyskinesia (1991) (0)
- Neuronal gamma aminobutyric acid hypofunction in tardive dyskinesia cerebrospinal fluid gamma aminobutyric acid levels and saccadic eye movements (1986) (0)
- Dopamine agonist therapy of naturally occurring and drug-induced hyperkinetic extrapyramidal disorders (1979) (0)
- Reduced task-evoked pupillary response in preparation for an executive cognitive control response among individuals across the psychosis spectrum (2022) (0)
- An FMRI study of language organization in schizophrenia (2003) (0)
- Glutamate, glutamine, NAA, and GABA levels in hippocampus in schizophrenia as measured by 1H-MRS at 3T (2010) (0)
- Measures of Social Cognition The Wechsler ACS Social Perception Subtest : A Preliminary Comparison With Other (2012) (0)
- Ketamine Dose Response of Cortical rCBF (1998) (0)
- Deficit and non-deficit schizophrenia: Sleep, occulomotor amd MRI studies (1990) (0)
- 3.2 Can Neurobiological Subgroups in Psychotic Illness Advantage Drug DISCOVERY (2017) (0)
- NDT_A_308615 1621..1631 (2021) (0)
- 469 Ketamine induced cerebellarcingulate rCBF correlations and rCBF patterns in normal volunteers (NV) and schizophrenic patients (SZ) (1997) (0)
- 350 Implicit motor learning and memory in schizophrenia (1997) (0)
- Introduction: evaluating clinical trial data from schizophrenia research. (2001) (0)
- The genomic underpinnings of oscillatory biomarkers supporting successful memory encoding in humans (2019) (0)
- Factors predicting patient withdrawal from long-term treatment of schizophrenia (2007) (0)
- Schizophrenia, VII (2003) (0)
- The human genome sequence: the human genome ii: sources of genetic variation. (2001) (0)
- 5 – Neurophysiological and cognitive phenotypes across the schizophrenia–bipolar disorder boundary (2008) (0)
- 63 Symptoms cluster analysis on and off neuroleptic medication (1997) (0)
- Images in neuroscience. Cognition: interference. (2000) (0)
- Peripheral Inflammatory Markers Are Associated With Neural Activity During the Auditory Oddball Task (2021) (0)
- A-38Exploratory and Confirmatory Factor Analysis Converge on a Unitary Construct Underlying BACS Performance Across Psychotic Disorders, Their First-Degree Relatives, and Healthy Volunteers (2015) (0)
- Social recognition in mice: Behavioral disruption with ketamine and blockade with antipsychotic drug (2003) (0)
- Images in neuroscience. In vivo visualization of the cortical surface. (1994) (0)
- Brain development, VIII (1998) (0)
- CPNP 2019 Annual Meeting Poster Abstracts (2019) (0)
- P555. Early and Steady-State Visual Neuro-Oscillations Across the Psychosis Spectrum (2022) (0)
- Pharmacologic characterization of parallel cortical-subcortical circuits in schizophrenics with tardive dyskinesia (1993) (0)
- O11.4. DIAGNOSIS AND BIOTYPE COMPARISON ACROSS THE PSYCHOSIS SPECTRUM: INVESTIGATING WHITE MATTER MICROSTRUCTURAL DIFFERENCES FROM THE BIPOLAR-SCHIZOPHRENIA NETWORK ON INTERMEDIATE PHENOTYPES (B-SNIP) STUDY USING FREE-WATER IMAGING (2019) (0)
- Inter-Device Reliability of Swept Source and Spectral Domain Optical Coherence Tomography Retinal Structure Measurements in Schizophrenia (2021) (0)
- 108. Consolidation Across Multiple Levels of Analysis for Parsing Biological Heterogeneity in Psychosis (2018) (0)
- Drs. Tamminga and Chase Reply (1979) (0)
- Cortex, VII: The hippocampus in epilepsy (1995) (0)
- 493 Ketamine induced time effect by principal component analysis (1997) (0)
- 292 Response Time (RT) and the odds of making a correcf choice (1997) (0)
- Brain Development, III: Cerebral Cortex (1998) (0)
- 2010 in Review. (2010) (0)
- TOWARDS PERSONALIZED MEDICATION IN SCHIZOPHRENIA: HYPOTHESIS-GENERATING FINDINGS ON PREDICTORS OF TREATMENT RESPONSE AND WITHDRAWAL (2008) (0)
- B-SNIP Psychosis Biotypes: Replication and Validation (2021) (0)
- Genetic Topography of Cortical thickness: A BSNIP Study (2020) (0)
- 965. Investigating Brain Structure Across Bipolar Disorder Subtypes: Findings from the Psychosis Affective Research Domain Intermediate Phenotypes (PARDIP) Study (2017) (0)
- 572. Cannabis Use and Matrix Metalloproteases in Schizophrenia (2017) (0)
- Longitudinal Stability of Psychosis Biomarkers: Findings From the Bipolar-Schizophrenia Network for Intermediate Phenotypes (B-SNIP) (2021) (0)
- Remoxipride therapy in poorly responsive schizophrenics (1991) (0)
- Serotonin binding sites in the brain of schizophrenic suicide victims (1993) (0)
- Intrinsic activity of dopamine agonists and partial agonists at the cloned dopamine D4.4 receptor (1995) (0)
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