Carole LaBonne
Developmental and Stem Cell Biologist
Carole LaBonne's AcademicInfluence.com Rankings
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Biology
Carole LaBonne's Degrees
- PhD Developmental Biology Stanford University
Why Is Carole LaBonne Influential?
(Suggest an Edit or Addition)According to Wikipedia, Carole LaBonne is a Developmental and Stem Cell Biologist at Northwestern University. She is the Erastus O. Haven Professor of Life Sciences, and Chair of the Department of Molecular Biosciences. Education and early career LaBonne received her bachelor's degree from the University of Rochester, doing research with Sayeeda Zain on the molecular basis of Alzheimer's disease. Inspired by the work of famed embryologist and Rochester emeritus professor Johannes Holtfreter, LaBonne pursued doctoral work at Harvard University studying germ layer formation using Xenopus as a model. As a National Science Foundation pre-doctoral Fellow working with Malcolm Whitman, LaBonne characterized the role of FGF signaling in formation of the mesendoderm. During her doctoral study, LaBonne discovered that activin-mediated mesoderm induction required FGF signaling and elucidated the role of RAS-Map Kinase signaling in this process.
Carole LaBonne's Published Works
Published Works
- Neural crest induction in Xenopus: evidence for a two-signal model. (1998) (517)
- Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migration. (2000) (254)
- Mesoderm induction by activin requires FGF-mediated intracellular signals. (1994) (250)
- Molecular mechanisms of neural crest formation. (1999) (240)
- The protooncogene c-myc is an essential regulator of neural crest formation in xenopus. (2003) (204)
- Role of MAP kinase in mesoderm induction and axial patterning during Xenopus development. (1995) (170)
- Tumor Metastasis: A New Twist on Epithelial–Mesenchymal Transitions (2004) (162)
- SoxE factors function equivalently during neural crest and inner ear development and their activity is regulated by SUMOylation. (2005) (160)
- Noelin-1 is a secreted glycoprotein involved in generation of the neural crest (2000) (135)
- Setting appropriate boundaries: fate, patterning and competence at the neural plate border. (2014) (132)
- The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1 (2011) (130)
- Induction of the neural crest state: control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions. (2012) (115)
- Shared regulatory programs suggest retention of blastula-stage potential in neural crest cells (2015) (110)
- Xenopus Id3 is required downstream of Myc for the formation of multipotent neural crest progenitor cells (2005) (107)
- Localization of MAP kinase activity in early Xenopus embryos: implications for endogenous FGF signaling. (1997) (106)
- Induction and patterning of the neural crest, a stem cell-like precursor population. (1998) (100)
- SoxE factors as multifunctional neural crest regulatory factors. (2010) (89)
- X-ray phase-contrast in vivo microtomography probes new aspects of Xenopus gastrulation (2013) (87)
- Slug stability is dynamically regulated during neural crest development by the F-box protein Ppa (2006) (85)
- Time-lapse X-ray phase-contrast microtomography for in vivo imaging and analysis of morphogenesis (2014) (80)
- Targeted inhibition of Snail family zinc finger transcription factors by oligonucleotide-Co(III) Schiff base conjugate (2009) (74)
- Interactions between Twist and other core epithelial–mesenchymal transition factors are controlled by GSK3-mediated phosphorylation (2013) (69)
- Neural induction in Xenopus requires inhibition of Wnt-β-catenin signaling (2006) (64)
- Targeted Inactivation of Snail Family EMT Regulatory Factors by a Co(III)-Ebox Conjugate (2012) (58)
- SUMOylated SoxE factors recruit Grg4 and function as transcriptional repressors in the neural crest (2012) (42)
- Neural induction in Xenopus requires inhibition of Wnt-beta-catenin signaling. (2006) (41)
- A slug, a fox, a pair of sox: transcriptional responses to neural crest inducing signals. (2004) (37)
- A Drosophila single-strand DNA/RNA-binding factor contains a high-mobility-group box and is enriched in the nucleolus. (1993) (34)
- Modulating the activity of neural crest regulatory factors. (2007) (32)
- Sox5 Is a DNA-binding cofactor for BMP R-Smads that directs target specificity during patterning of the early ectoderm. (2014) (29)
- The LIM adaptor protein LMO4 is an essential regulator of neural crest development. (2012) (27)
- FGF mediated MAPK and PI3K/Akt Signals make distinct contributions to pluripotency and the establishment of Neural Crest (2018) (27)
- Histone deacetylase activity has an essential role in establishing and maintaining the vertebrate neural crest (2018) (26)
- Sorting Sox: Diverse Roles for Sox Transcription Factors During Neural Crest and Craniofacial Development (2020) (20)
- Vertebrate Development: Wnt Signals at the Crest (2002) (20)
- Overexpression of amyloid precursor protein A4 (beta-amyloid) immunoreactivity in genetically transformed cells: implications for a cellular model of Alzheimer amyloidosis. (1989) (17)
- Preface: the neural crest--from stem cell formation to migration and differentiation. (2012) (15)
- Metal Ion Fluxes Controlling Amphibian Fertilization (2021) (12)
- Wnt Signaling: A Shaggy Dogma Tale (2006) (12)
- Modeling human development and disease in Xenopus. Preface. (2015) (7)
- A transition from SoxB1 to SoxE transcription factors is essential for progression from pluripotent blastula cells to neural crest cells (2018) (7)
- Multiple roles for Wnt signaling in the development of the vertebrate neural crest (2007) (3)
- Program/Abstract # 167The role of snail family transcription factors in neural crest development and tumor progression (2009) (2)
- SUMO weighs in on a photoreceptor finish. (2009) (1)
- The developmental and evolutionary origins of cellular pluripotency in the vertebrate neural crest. (2022) (1)
- SUMO regulation of SoxE factors during neural crest development (2011) (1)
- LMO4 modulates slug/snail function in neural crest development (2011) (1)
- Wrestling with melanocyte development (2008) (0)
- The role of slug in neural crest (2008) (0)
- Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions (2022) (0)
- The role of LMO4 in neural crest development (2009) (0)
- Trap230 and neural crest development (2008) (0)
- Program/Abstract # 154Context-dependent regulation of SoxE activity (2009) (0)
- Micron resolved in vivo tomographic time-lapse series of early neurulation in Xenopus laevis acquired by X-ray propagation based phase-contrast imaging (2016) (0)
- Production and Characterization of Monoclonal antibodies to Xenopus proteins (2022) (0)
- Regulating the function of Twist, an essential factor in neural crest development and tumor progress (2011) (0)
- Role of SoxD proteins in regulating SoxE function during neural crest development (2011) (0)
- SoxE factors can function as SUMO-dependent transcriptional repressors by recruiting transcriptional co-repressor Grg4 (2009) (0)
- Dynamics of a single cell fate decision (2020) (0)
- REALISATION DE CAPSULES EN GADOLINIUM POUR DETECTEURS-DOSIMETRES. (Development of Gadolinium Capsules for Detectors and Dosimeters. Technical Note AME 65-17). (1965) (0)
- Production and characterization of monoclonal antibodies to Xenopus proteins. (2023) (0)
- COORDINATE REGULATION OF CORE EMT REGULTORY FACTORS IS ESSENTIAL FOR MIGRATORY AND INVASIVE BEHAVIOR (2013) (0)
- Regulation of twist function in developmental and pathological epithelial-mesenchymal transitions (2008) (0)
- Corrigendum to "A transition from SoxB1 to SoxE transcription factors is essential for progression from pluripotent blastula cells to neural crest cells" [Dev Biol. 2018 Dec 15 444(2):50-61]. (2022) (0)
- Impact of the Xenopus system on the missions of the NCI (2009) (0)
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