Carolyn Calfee
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American physician
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Philosophy
Carolyn Calfee's Degrees
- Doctorate Medicine University of California, San Francisco
- Masters Public Health University of California, Berkeley
Why Is Carolyn Calfee Influential?
(Suggest an Edit or Addition)According to Wikipedia, Carolyn S. Calfee is a Professor of Medicine and Anaesthesia at the University of California, San Francisco. She works in intensive care at the UCSF Medical Center where she specialises in acute respiratory distress syndrome. During the COVID-19 pandemic Calfee studied why SARS-CoV-2 patients experienced such different symptoms.
Carolyn Calfee's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. (2014) (837)
- A living WHO guideline on drugs for covid-19 (2020) (627)
- Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial. (2015) (598)
- Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes (2020) (583)
- Is a "Cytokine Storm" Relevant to COVID-19? (2020) (528)
- Acute Respiratory Distress Syndrome Subphenotypes Respond Differently to Randomized Fluid Management Strategy (2016) (482)
- Acute respiratory distress syndrome (1996) (449)
- Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial. (2019) (369)
- Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial. (2018) (355)
- COVID-19-associated acute respiratory distress syndrome: is a different approach to management warranted? (2020) (333)
- Acute respiratory distress syndrome (2019) (324)
- Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury (2008) (295)
- Critical Role of Activated Protein C in Early Coagulopathy and Later Organ Failure, Infection and Death in Trauma Patients (2012) (260)
- Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury. (2018) (257)
- Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion (2009) (256)
- Distinct molecular phenotypes of direct vs indirect ARDS in single-center and multicenter studies. (2014) (256)
- Toward Smarter Lumping and Smarter Splitting: Rethinking Strategies for Sepsis and Acute Respiratory Distress Syndrome Clinical Trial Design. (2016) (231)
- Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS (2018) (227)
- Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders* (2007) (216)
- Pulmonary toxicity of e-cigarettes. (2017) (214)
- Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults (2018) (211)
- Plasma angiopoietin-2 predicts the onset of acute lung injury in critically ill patients. (2013) (205)
- Plasma angiopoietin-2 in clinical acute lung injury: Prognostic and pathogenetic significance* (2012) (194)
- Nonventilatory treatments for acute lung injury and ARDS. (2007) (184)
- Identification and validation of distinct biological phenotypes in patients with acute respiratory distress syndrome by cluster analysis (2017) (180)
- Update: Interim Guidance for Health Care Providers Evaluating and Caring for Patients with Suspected E-cigarette, or Vaping, Product Use Associated Lung Injury — United States, October 2019 (2019) (175)
- Biomarkers of lung epithelial injury and inflammation distinguish severe sepsis patients with acute respiratory distress syndrome (2013) (173)
- Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis. (2010) (172)
- Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study (2018) (172)
- Therapeutic potential of mesenchymal stem cells for severe acute lung injury. (2010) (170)
- Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis. (2010) (159)
- Therapeutic strategies for severe acute lung injury (2010) (154)
- Physiologic Analysis and Clinical Performance of the Ventilatory Ratio in Acute Respiratory Distress Syndrome (2019) (149)
- Active and passive cigarette smoking and acute lung injury after severe blunt trauma. (2011) (143)
- Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome* (2016) (143)
- Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study (2020) (143)
- One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome (2014) (140)
- Clara cell protein (CC16), a marker of lung epithelial injury, is decreased in plasma and pulmonary edema fluid from patients with acute lung injury. (2009) (123)
- Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS. (2015) (123)
- ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio. (2011) (122)
- FLASH: a next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences (2018) (120)
- Development and validation of parsimonious algorithms to classify acute respiratory distress syndrome phenotypes: a secondary analysis of randomised controlled trials. (2020) (118)
- Soluble intercellular adhesion molecule-1 and clinical outcomes in patients with acute lung injury (2009) (111)
- Fibrinogen and platelet contributions to clot formation: Implications for trauma resuscitation and thromboprophylaxis (2014) (110)
- Use of risk reclassification with multiple biomarkers improves mortality prediction in acute lung injury (2011) (106)
- Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19 (2021) (104)
- ARDS Subphenotypes: Understanding a Heterogeneous Syndrome (2020) (103)
- Global absence and targeting of protective immune states in severe COVID-19 (2021) (100)
- Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury. (2014) (99)
- Global Absence and Targeting of Protective Immune States in Severe COVID-19 (2020) (99)
- Elevated levels of the receptor for advanced glycation end products, a marker of alveolar epithelial type I cell injury, predict impaired alveolar fluid clearance in isolated perfused human lungs. (2009) (98)
- Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses (2020) (97)
- Phenotypes in acute respiratory distress syndrome: moving towards precision medicine (2019) (96)
- Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome* (2015) (95)
- Clinical Predictors of Hospital Mortality Differ Between Direct and Indirect ARDS (2017) (93)
- Stability of ARDS subphenotypes over time in two randomised controlled trials (2018) (89)
- Diagnostic workup for ARDS patients (2016) (88)
- Acute respiratory distress syndrome (2021) (88)
- Genome Wide Association Identifies PPFIA1 as a Candidate Gene for Acute Lung Injury Risk Following Major Trauma (2012) (87)
- Lung Microbiota Is Related to Smoking Status and to Development of Acute Respiratory Distress Syndrome in Critically Ill Trauma Patients (2017) (85)
- Subphenotypes in critical care: translation into clinical practice. (2020) (81)
- Plasma receptor for advanced glycation end-products predicts duration of ICU stay and mechanical ventilation in patients after lung transplantation. (2007) (78)
- Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis (2018) (75)
- Identification of Acute Kidney Injury Subphenotypes with Differing Molecular Signatures and Responses to Vasopressin Therapy (2019) (75)
- Early Acute Lung Injury: Criteria for Identifying Lung Injury Prior to the Need for Positive Pressure Ventilation* (2013) (74)
- Identification of early acute lung injury at initial evaluation in an acute care setting prior to the onset of respiratory failure. (2009) (74)
- Phenotypes and personalized medicine in the acute respiratory distress syndrome (2020) (72)
- Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data (2018) (69)
- The influence of perceived control of asthma on health outcomes. (2006) (68)
- Characterizing the gut microbiome in trauma: significant changes in microbial diversity occur early after severe injury (2017) (67)
- Plasma angiopoietin-2 outperforms other markers of endothelial injury in prognosticating pediatric ARDS mortality. (2016) (66)
- The Association Between Physiologic Dead-Space Fraction and Mortality in Subjects With ARDS Enrolled in a Prospective Multi-Center Clinical Trial (2014) (66)
- Clinical immunology: Culprits with evolutionary ties (2010) (64)
- Determining the aetiology of pulmonary oedema by the oedema fluid-to-plasma protein ratio (2009) (64)
- FGF-23 and PTH levels in patients with acute kidney injury: A cross-sectional case series study (2011) (63)
- Acute Respiratory Distress Syndrome Phenotypes (2019) (63)
- The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury. (2012) (62)
- Is there still a role for the lung injury score in the era of the Berlin definition ARDS? (2014) (62)
- Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome (2017) (61)
- Personalized medicine for ARDS: the 2035 research agenda (2016) (60)
- Biomarkers increase detection of active smoking and secondhand smoke exposure in critically ill patients* (2011) (59)
- Gender Parity in Critical Care Medicine. (2017) (59)
- Assessment of industry data on pulmonary and immunosuppressive effects of IQOS (2018) (58)
- Practitioner's Guide to Latent Class Analysis: Methodological Considerations and Common Pitfalls. (2020) (58)
- Latent Class Analysis Reveals COVID-19–related Acute Respiratory Distress Syndrome Subgroups with Differential Responses to Corticosteroids (2021) (57)
- Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome (2014) (57)
- Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome (2015) (57)
- Mesenchymal stromal cell extracellular vesicles rescue mitochondrial dysfunction and improve barrier integrity in clinically relevant models of ARDS (2020) (55)
- Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death (2016) (54)
- Update: Interim Guidance for Health Care Providers for Managing Patients with Suspected E-cigarette, or Vaping, Product Use–Associated Lung Injury — United States, November 2019 (2019) (54)
- Redefining critical illness (2022) (52)
- Long-Term Ozone Exposure Increases the Risk of Developing the Acute Respiratory Distress Syndrome. (2016) (52)
- Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis (2020) (51)
- Early release of soluble receptor for advanced glycation endproducts after severe trauma in humans. (2010) (50)
- Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation (2016) (50)
- The acute respiratory distress syndrome following isolated severe traumatic brain injury (2016) (49)
- Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial (2021) (48)
- Fluid administration and monitoring in ARDS: which management? (2020) (46)
- Sepsis Subclasses: A Framework for Development and Interpretation. (2021) (45)
- Beyond Low Tidal Volume Ventilation: Treatment Adjuncts for Severe Respiratory Failure in Acute Respiratory Distress Syndrome (2018) (44)
- Silencing Bruton's tyrosine kinase in alveolar neutrophils protects mice from LPS/immune complex-induced acute lung injury. (2014) (43)
- Update: Interim Guidance for Health Care Professionals Evaluating and Caring for Patients with Suspected E-cigarette, or Vaping, Product Use–Associated Lung Injury and for Reducing the Risk for Rehospitalization and Death Following Hospital Discharge — United States, December 2019 (2020) (43)
- Prevalence and Impact of Active and Passive Cigarette Smoking in Acute Respiratory Distress Syndrome (2014) (42)
- Interstitial lung diseases in the hospitalized patient (2015) (41)
- Upper airway gene expression differentiates COVID-19 from other acute respiratory illnesses and reveals suppression of innate immune responses by SARS-CoV-2 (2020) (41)
- Elevated soluble thrombomodulin is associated with organ failure and mortality in children with acute respiratory distress syndrome (ARDS): a prospective observational cohort study (2015) (41)
- Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma (2019) (39)
- Possible hepatotoxicity of IQOS (2018) (38)
- Machine Learning Classifier Models Can Identify ARDS Phenotypes Using Readily Available Clinical Data. (2020) (37)
- Plasma interleukin-8 is not an effective risk stratification tool for adults with vasopressor-dependent septic shock* (2010) (37)
- Estimated dead space fraction and the ventilatory ratio are associated with mortality in early ARDS (2019) (37)
- Advancing precision medicine for acute respiratory distress syndrome (2021) (36)
- Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01 (2021) (36)
- Donor Smoking Is Associated With Pulmonary Edema, Inflammation and Epithelial Dysfunction in Ex Vivo Human Donor Lungs (2014) (35)
- Gender Differences in Authorship of Critical Care Literature. (2019) (34)
- Differences in degree, differences in kind: Characterizing lung injury in trauma (2015) (33)
- Dose-Dependent Pulmonary Toxicity of Aerosolized Vitamin E Acetate. (2020) (33)
- Comparison of thermodilution measured extravascular lung water with chest radiographic assessment of pulmonary oedema in patients with acute lung injury (2013) (33)
- Erratum to: Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome (2015) (32)
- Metagenomic comparison of tracheal aspirate and mini-bronchial alveolar lavage for assessment of respiratory microbiota. (2019) (31)
- Recent advances in mechanical ventilation. (2005) (30)
- Incorporating Inflammation into Mortality Risk in Pediatric Acute Respiratory Distress Syndrome (2017) (30)
- A simple classification model for hospital mortality in patients with acute lung injury managed with lung protective ventilation* (2011) (29)
- Environmental risk factors for acute respiratory distress syndrome. (2014) (29)
- Effect of Simvastatin on Physiological and Biological Outcomes in Patients Undergoing Esophagectomy: A Randomized Placebo-Controlled Trial (2014) (29)
- Early Plasma Matrix Metalloproteinase Profiles. A Novel Pathway in Pediatric Acute Respiratory Distress Syndrome (2019) (29)
- A Simple and Robust Bedside Model for Mortality Risk in Pediatric Patients With Acute Respiratory Distress Syndrome* (2016) (28)
- Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care: NHLBI Working Group Report. (2020) (28)
- A living WHO guideline on drugs for covid-19 (2022) (28)
- Performance of interleukin-27 as a sepsis diagnostic biomarker in critically ill adults. (2014) (28)
- Precision medicine in acute respiratory distress syndrome: workshop report and recommendations for future research (2020) (27)
- Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS (2021) (26)
- Positive Cumulative Fluid Balance Is Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome in the Setting of Acute Kidney Injury (2019) (26)
- Cigarette Smoke Exposure Worsens Endotoxin-Induced Lung Injury and Pulmonary Edema in Mice (2017) (26)
- Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS (2021) (26)
- Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome (2016) (26)
- Intensive care unit scoring systems outperform emergency department scoring systems for mortality prediction in critically ill patients: a prospective cohort study (2014) (26)
- The relationship between plasma lipid peroxidation products and primary graft dysfunction after lung transplantation is modified by donor smoking and reperfusion hyperoxia. (2016) (26)
- Machine Learning Classi fi er Models Can Identify Acute Respiratory Distress Syndrome Phenotypes Using Readily Available Clinical Data (2020) (25)
- Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19 (2021) (24)
- Plasma sRAGE Acts as Genetically Regulated Causal Intermediate in Sepsis-Associated ARDS. (2019) (24)
- External validation of a biomarker and clinical prediction model for hospital mortality in acute respiratory distress syndrome (2017) (24)
- Rural Social Service Disparities and Creative Social Work Solutions for Rural Families Across the Life Span (2013) (24)
- COVID-19 ARDS is characterized by a dysregulated host response that differs from cytokine storm and is modified by dexamethasone (2021) (23)
- Plasma granulocyte colony-stimulating factor levels correlate with clinical outcomes in patients with acute lung injury* (2009) (23)
- Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report (2022) (23)
- Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis (2022) (23)
- NIH Workshop Report: E-cigarette or Vaping Product Use Associated Lung Injury (EVALI): Developing a Research Agenda. (2020) (23)
- Biomarkers of ARDS: what’s new? (2016) (23)
- Peripheral blood leukocyte telomere length is associated with survival of sepsis patients (2020) (22)
- Perhaps it's not the platelet: Ristocetin uncovers the potential role of von Willebrand factor in impaired platelet aggregation following traumatic brain injury (2018) (22)
- Building A Full-Service School: A Step-by-Step Guide (1998) (22)
- Biomarkers and Precision Medicine: State of the Art. (2020) (22)
- Derivation and validation of a two-biomarker panel for diagnosis of ARDS in patients with severe traumatic injuries (2017) (21)
- Prospective Assessment of the Feasibility of a Trial of Low‐Tidal Volume Ventilation for Patients with Acute Respiratory Failure (2018) (21)
- Comparison of chest radiograph scoring to lung weight as a quantitative index of pulmonary edema in organ donors (2012) (21)
- Plasma sRAGE Acts as a Genetically Regulated Causal Intermediate in Sepsis-associated Acute Respiratory Distress Syndrome : Plasma sRAGE as a Causal Intermediate in ARDS Risk (2019) (20)
- Latent Class Analysis-Derived Subphenotypes are Generalizable to Observational Cohorts of Acute Respiratory Distress Syndrome: A Prospective Study (2021) (20)
- Clinically Relevant Model of Pneumococcal Pneumonia, ARDS, and Non-Pulmonary Organ Dysfunction in Mice. (2019) (20)
- Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study (2019) (20)
- Cigarette smoke exposure worsens acute lung injury in antibiotic-treated bacterial pneumonia in mice. (2018) (20)
- Characterization of distinct coagulopathic phenotypes in injury: Pathway-specific drivers and implications for individualized treatment (2017) (19)
- Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs (2022) (18)
- Identification of phenotypes in paediatric patients with acute respiratory distress syndrome: a latent class analysis. (2021) (18)
- The ABO Histo-Blood Group, endothelial activation, and acute respiratory distress syndrome risk in critical illness. (2020) (17)
- A Research Agenda for Precision Medicine in Sepsis and Acute Respiratory Distress Syndrome: An Official American Thoracic Society Research Statement (2021) (17)
- COVID-19-Associated Lung Microvascular Endotheliopathy: A "From the Bench" Perspective. (2022) (17)
- Higher mini-BAL total protein concentration in early ARDS predicts faster resolution of lung injury measured by more ventilator-free days. (2017) (16)
- Prone Positioning in Awake, Nonintubated Patients With COVID-19: Necessity Is the Mother of Invention. (2020) (16)
- Promises and challenges of personalized medicine to guide ARDS therapy (2021) (15)
- Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial. (2022) (15)
- Health care utilization and the cost of posttraumatic acute respiratory distress syndrome care. (2018) (14)
- Human pulmonary endothelial cell permeability after exposure to LPS-stimulated leukocyte supernatants derived from patients with early sepsis. (2018) (14)
- E-Cigarette or Vaping Product Use–associated Lung Injury: Developing a Research Agenda. An NIH Workshop Report (2020) (14)
- Severe COVID-19 Infections-Knowledge Gained and Remaining Questions. (2020) (14)
- Fixing the leak: targeting the vascular endothelium in sepsis (2012) (14)
- Accuracy of the Radiographic Assessment of Lung Edema Score for the Diagnosis of ARDS (2021) (14)
- Towards a biological definition of ARDS: are treatable traits the solution? (2022) (13)
- Exposing the bidirectional effects of alcohol on coagulation in trauma: Impaired clot formation and decreased fibrinolysis in rotational thromboelastometry (2018) (13)
- Opening the Debate on the New Sepsis Definition. Precision Medicine: An Opportunity to Improve Outcomes of Patients with Sepsis. (2016) (13)
- Clearing the air. Smoking and incident asthma in adults. (2015) (12)
- Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19 (2021) (12)
- Immunophenotyping assessment in a COVID-19 cohort (IMPACC): A prospective longitudinal study (2021) (12)
- Detection of Pneumonia Pathogens from Plasma Cell-Free DNA. (2020) (11)
- The radiographic assessment of lung edema (RALE) score has excellent diagnostic accuracy for ARDS (2019) (11)
- Clinical trial design during and beyond the pandemic: the I-SPY COVID trial (2022) (11)
- The search for diagnostic markers in sepsis: many miles yet to go. (2012) (11)
- ECMO During Respiratory Pandemics: Past, Present, and Future. (2022) (11)
- Misclassification of acute respiratory distress syndrome after traumatic injury: The cost of less rigorous approaches (2015) (10)
- Machine Learning Classifier Models Can Identify ARDS Phenotypes Using Readily Available Clinical Data (2019) (10)
- Long-term ozone exposure is positively associated with telomere length in critically ill patients. (2020) (10)
- ARDS in 2015: new clinical directions, new biological insights. (2015) (9)
- Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis (2020) (9)
- Clinician Recognition of the Acute Respiratory Distress Syndrome: Risk Factors for Under-Recognition and Trends Over Time* (2020) (9)
- Six-month and 12-month patient outcomes based on inflammatory subphenotypes in sepsis-associated ARDS: secondary analysis of SAILS-ALTOS trial (2021) (9)
- A new frontier in ARDS trials: phenotyping before randomisation. (2019) (9)
- PREDICTORS OF POST-INJURY ARDS: LUNG INJURY PERSISTS IN THE ERA OF HEMOSTATIC RESUSCITATION. (2019) (9)
- Comparison of machine learning clustering algorithms for detecting heterogeneity of treatment effect in acute respiratory distress syndrome: A secondary analysis of three randomised controlled trials (2021) (9)
- Therapeutic value of a lung protective ventilation strategy in acute lung injury. (2005) (8)
- Association between pre-operative biological phenotypes and postoperative pulmonary complications: An unbiased cluster analysis (2018) (8)
- Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of Systemic Inflammatory Response Syndrome, Sequential Organ Failure Assessment, and Quick Sequential Organ Failure Assessment. (2019) (8)
- Impaired antibacterial immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19 (2021) (8)
- The Canary in the Coal Mine Is Coughing: Electronic Cigarettes and Respiratory Symptoms in Adolescents. (2017) (7)
- Twenty‐Four‐Hour Cardiovascular Effects of Electronic Cigarettes Compared With Cigarette Smoking in Dual Users (2020) (7)
- A Neutrophil Subset Defined by Intracellular Olfactomedin 4 is Associated with Mortality in Sepsis. (2020) (7)
- Phenotyping in acute respiratory distress syndrome: state of the art and clinical implications (2021) (7)
- Clinical problem-solving. Anchors away. (2007) (7)
- Plasma Metabolites in Early Sepsis Identify Distinct Clusters Defined by Plasma Lipids (2021) (7)
- Elevated plasma levels of TIMP-3 are associated with a higher risk of acute respiratory distress syndrome and death following severe isolated traumatic brain injury (2018) (6)
- A manifesto for the future of ICU trials (2020) (6)
- Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of Systemic Inflammatory Response Syndrome, Sequential Organ Failure Assessment, and Quick Sequential Organ Failure Assessment. (2020) (6)
- Using Best Subsets Regression to Identify Clinical Characteristics and Biomarkers Associated with Sepsis-Associated Acute Kidney Injury. (2020) (6)
- Peeking under the Hood of Acute Respiratory Distress Syndrome Phenotypes: Deeper Insights into Biological Heterogeneity (2019) (6)
- Cigarette Smoking and ARDS After Blunt Trauma: The Influence of Changing Smoking Patterns and Resuscitation Practices. (2020) (6)
- Acute Respiratory Distress Syndrome Subphenotypes beyond the Syndrome: A Step toward Treatable Traits? (2021) (6)
- I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations (2022) (6)
- Clinical Evidence of Early Acute Lung Injury Often Precedes the Diagnosis of ALI (2013) (6)
- Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults (2022) (5)
- Strengthening Connections Between Schools and Afterschool Programs (2006) (5)
- Reply to "Letter to the Editor: Pulmonary toxicity of electronic cigarettes: more doubts than certainties". (2017) (5)
- Metagenomic prediction of antimicrobial resistance in critically ill patients with lower respiratory tract infections (2022) (5)
- Prognostic factors for development of acute respiratory distress syndrome following traumatic injury: a systematic review and meta-analysis (2021) (5)
- Immediate myeloid depot for SARS-CoV-2 in the human lung (2022) (5)
- Aerosolized beta-adrenergic agonist therapy reduces pulmonary edema following lung surgery. (2008) (5)
- Mass cytometry reveals a conserved immune trajectory of recovery in hospitalized COVID-19 patients (2022) (5)
- Lack of Clinical Benefit of Interferon β-1a Among Patients With Severe Acute Respiratory Distress Syndrome: Time to Overhaul Drug Trials in ARDS? (2020) (5)
- Plasma SARS-CoV-2 nucleocapsid antigen levels are associated with progression to severe disease in hospitalized COVID-19 (2022) (4)
- Pulmonary Dead Space Monitoring: Identifying Subjects With ARDS at Risk of Developing Right Ventricular Dysfunction (2019) (4)
- Consistent Ards Endotypes Are Identified Using Minimal Data From A United Kingdom Clinical Trial (2017) (4)
- Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome (2016) (4)
- Aerosolized Vitamin E Acetate Causes Oxidative Injury in Mice and in Alveolar Macrophages. (2022) (4)
- Quantification of Pulmonary Edema on Chest Radiograph Compared with Direct Measurements of Extravascular Lung Water in Humans. (2009) (3)
- Focusing on the alveolar epithelium: Alveolar fluid clearance in diffuse versus focal acute respiratory distress syndrome. (2016) (3)
- Genome-Wide Association Study Of Acute Lung Injury Risk Loci In The Ispaar Consortium (2011) (3)
- Hospital trajectories and early predictors of clinical outcomes differ between SARS-CoV-2 and influenza pneumonia (2022) (3)
- Sonographic B-Lines, Fluid Resuscitation, and Hypoxemia in Malawian Patients with Suspected Sepsis (2020) (3)
- Updates in the Management of Acute Lung Injury (2012) (3)
- Assessing the importance of interleukin-6 in COVID-19 – Authors' reply (2021) (3)
- "Pulmonary and Critical Care Considerations for E-cigarette, or Vaping, Product Use-Associated Lung Injury (EVALI)". (2022) (3)
- Defining phenotypes and treatment effect heterogeneity to inform acute respiratory distress syndrome and sepsis trials: secondary analyses of three RCTs (2021) (3)
- Immunotherapy in COVID-19: why, who, and when? (2021) (3)
- Health Care Utilization and the Cost of Post-Traumatic ARDS Care. (2018) (3)
- Global Absence and Targeting of Protective Immune States in Severe COVID-19. (2020) (3)
- Titrating Oxygen Therapy in Critically Ill Patients. (2021) (3)
- 18: Pulmonary Edema in Organ Donors: Comparison of Chest Radiograph Scoring to Lung Weight as a Quantitative Index of Lung Water (2009) (2)
- COVID-19 ARDS is characterized by a dysregulated host response that differs from cytokine storm and may be modified by dexamethasone (2021) (2)
- Inflammasomes Assemble: Cytoplasmic Guardians or Fallen Heroes? (2019) (2)
- Research Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue (2009) (2)
- Cigarette Smoke Exposure and ARDS in Sepsis: Epidemiology, Clinical Features, and Biologic Markers. (2022) (2)
- Immune Modulation in Sepsis, ARDS, and Covid-19 — The Road Traveled and the Road Ahead (2022) (2)
- Strengthening Connections between Schools and Afterschool Programs. Revised Edition. (2006) (2)
- Building a Full Service School: Florida's Model of Collaboration for School-Based and School-Linked Services. (1995) (2)
- KGF Enhances The Pulmonary Production Of Epithelial Repair Factors Following Endotoxin Induced Lung Inflammation And Injury In Human Volunteers (2011) (2)
- Active And Passive Cigarette Smoking Are Associated With Acute Lung Injury Following Severe Blunt Trauma (2011) (2)
- Impact of E-Cigarette Aerosol on Primary Human Alveolar Epithelial Type 2 Cells. (2022) (2)
- Development and Validation of Parsimonious Algorithms to Classify ARDS Phenotypes: Secondary Analyses of Randomised Controlled Trials (2019) (2)
- New Insights into Clinical and Mechanistic Heterogeneity of the Acute Respiratory Distress Syndrome: Summary of the Aspen Lung Conference 2021. (2022) (2)
- Biomarkers of lung injury in primary graft dysfunction following lung transplantation. (2007) (2)
- Comprehensive Program Planning for the Integration of 21st Century Learning Center After-School Programs with Regular Day Programs and Community Partners. (1999) (2)
- Platelet aggregation after blunt trauma is associated with the acute respiratory distress syndrome and altered by cigarette smoke exposure (2017) (2)
- Ventilatory Ratio Is a Valuable Prognostic Indicator in an Observational Cohort of Patients With ARDS (2022) (2)
- Environmental Risk Factors for ARDS (2014) (2)
- Plasma Receptor for Advanced Glycation Endproducts Predicts Duration of ICU Stay and Mechanical Ventilation in Patients Following Lung Transplantation (2009) (2)
- Extracorporeal Membrane Oxygenation during Respiratory Pandemics: Past, Present, and Future (2022) (2)
- Reply: Next Step to Understanding Subphenotypes of Acute Respiratory Distress Syndrome. (2017) (2)
- Plasma IL-8 As A Risk Stratification Tool For Adults With Septic Shock (2010) (2)
- Latent Class Models Identify Two Subphenotypes in Respiratory Distress Syndrome with Differential Response to Positive End-Expiratory Pressure (2015) (1)
- Precision medicine for cell therapy in acute respiratory distress syndrome - Authors' reply. (2019) (1)
- Implications of ECMO Bridging and Salvage Strategies on Mortality and PGD. (2020) (1)
- The attributable mortality of acute respiratory distress syndrome (2020) (1)
- Contemporary trends in PGD incidence, outcomes, and therapies. (2022) (1)
- Alternative Tobacco Product Use in Critically Ill Patients (2020) (1)
- A Metagenomic Comparison of Tracheal Aspirate and Mini-Bronchial Alveolar Lavage for Assessment of Respiratory Microbiota (2018) (1)
- Functional Transcriptomic Studies of Immune Responses and Endotoxin Tolerance in Early Human Sepsis (2022) (1)
- Early Acute Lung Injury: Criteria For Identifying Lung Injury Prior To The Need For Mechanical Ventilation (2012) (1)
- Effect Of Conservative Fluid Management On Endothelial Inflammation (Angiopoietin-2) In Patients With Acute Lung Injury (2011) (1)
- Publisher Correction: Global absence and targeting of protective immune states in severe COVID-19 (2021) (1)
- Plasma metabolic profiling implicates dysregulated lipid metabolism and glycolytic shift in hyperinflammatory ARDS. (2023) (1)
- Single Nucleotide Variant in FAS Associates With Organ Failure and Soluble Fas Cell Surface Death Receptor in Critical Illness (2021) (1)
- Biological Phenotyping in Sepsis and Acute Respiratory Distress Syndrome. (2022) (1)
- Combining Multiple Biomarkers Improves Risk Prediction in Patients with ALI in Both Derivation and Replication Cohorts. (2009) (1)
- ARDS: new mechanistic insights, new therapeutic directions. (2014) (1)
- Informed consent process in the ISPY COVID trial is ethically acceptable. (2022) (1)
- Baseline Plasma Soluble Thrombomodulin And Thrombomodulin Gene Polymorphisms Are Associated With Clinical Outcomes In Acute Lung Injury (2011) (1)
- Non-Invasive Diagnosis of the Etiology of Acute Pulmonary Edema Using the Edema Fluid-to-Plasma Protein Ratio. (2009) (1)
- Transepithelial nasal potential difference in patients with, and at risk of acute respiratory distress syndrome (2021) (1)
- ARDS Subphenotypes Beyond the Syndrome: A Step Towards Treatable Traits? (2021) (1)
- Public Comment submitted to FDA on Nicotine Exposure Warnings and Child-Resistant Packaging for Liquid Nicotine, Nicotine- Containing E-Liquid(s), and Other Tobacco Products; Request for Comments (2015) (1)
- Transepithelial Nasal Potential Difference Measurement Predicts The Development Of Acute Lung Injury (2012) (1)
- Nicotine-Containing E-cigarette Aerosol Increases Influenza-Induced Lung Protein Permeability and Impairs Viral Clearance in Mice (2020) (1)
- The Sonographic B-Line Score Is Associated with the Volume of Intravenous Fluid Given to Malawian Patients with Suspected Sepsis (2019) (1)
- To Catch a Fish (2012) (1)
- Genome Wide Association (GWA) Identifies Functional Susceptibility Loci For Trauma-Associated Acute Lung Injury (2010) (1)
- Plasma Levels Of The Receptor For Advanced Glycation End Products (RAGE) Are Elevated In Early Acute Lung Injury But Not In Severe Sepsis (2012) (1)
- Analysis of Immunoparalysis (2012) (1)
- Elevated ferritin is associated with systemic inflammation, inflammasome activation and mortality in Acute Respiratory Distress Syndrome (ARDS) (2022) (1)
- Therapeutic strategies for severe acute lung injury: Erratum (2010) (1)
- Pulmonary Edema and Biomarkers of Inflammation and Lung Epithelial Dysfunction Are Associated with Donor Smoking in the Ex Vivo Donor Lung (2013) (1)
- Impact of Popular E Cigarette Pods on Human Alveolar Epithelial Type 2 Cells: Implications for Long Term Use (2022) (0)
- Title: Integrating Host Response and Unbiased Microbe Detection for Lower Respiratory Tract Infection Diagnosis in Critically Ill Adults Running Title: Host-Microbe Sequencing for Critical LRTI Diagnosis (2018) (0)
- Alveolar Epithelial And Lung Endothelial Activation/Injury After Inhaled Lipopolysaccharide In Healthy Human Volunteers (2010) (0)
- The authors reply. (2019) (0)
- Biomarkers of Tobacco Exposure Are More Sensitive Than Smoking History in Critically Ill Adults. (2009) (0)
- Metagenomic prediction of antimicrobial resistance in critically ill patients with lower respiratory tract infections (2022) (0)
- NHLBI WORKSHOP Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care NHLBI Working Group Report (2020) (0)
- Focusing on the alveolar epithelium: Alveolar fluid clearance in ciffuse versus focal ARDS (2021) (0)
- Increased Expression Of Neutrophil-Related Genes In Patients With Early Sepsis-Induced 1 ARDS 2 3 (2015) (0)
- ASSOCIATION OF ANGIOPOIETIN-2 AND ATRIAL FIBRILLATION BURDEN IN CRITICALLY ILL PATIENTS (2019) (0)
- Stirrings in the Graveyard (2012) (0)
- Predicting PGD after Lung Transplantation (2021) (0)
- Reply to Kuindersma and Spronk: Time to Tailor the One-Size-Fits-All Approach? (2021) (0)
- Title Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome (2015) (0)
- Elevated Plasma Levels Of Soluble Endothelial Protein C Receptor (sEPCR) Are Associated With Increased Mortality And Longer Duration Of Organ Failure Among Patients With Acute Lung Injury (2012) (0)
- Nebulised aviptadil “futile” in I-SPY COVID-19 trial (2022) (0)
- Latent Class Analysis Identifies Novel Phenotypes of Severe COVID-19 Pneumonia (2023) (0)
- and PTH levels in patients with acute kidney injury: A cross-sectional case series study. (2011) (0)
- Latent Class Analysis-Derived Phenotypes Are Generalizable to Observational Cohorts of Acute Respiratory Distress Syndrome (ARDS) (2020) (0)
- Simple Prediction Rule For Hospital Mortality In Patients With Acute Lung Injury (2011) (0)
- Short and Long Term Exposure to Ambient Air Pollutants and Increased Risk of Acute Respiratory Distress Syndrome in Sepsis (2021) (0)
- Immediate myeloid depot for SARS-CoV-2 in the human lung (2022) (0)
- Genetic Inference Implicates the FAS Pathway in Systemic Organ Failure (2020) (0)
- The authors reply. (2016) (0)
- Prevention Of Pulmonary Inflammation And Cellular Injury By Simvastatin In A One Lung Ventilation Model Of ALI In Patients Undergoing Oesophagectomy (2012) (0)
- Molecular Phenotypes of Frailty in Lung Transplant Candidates (2022) (0)
- Novel Approach to Identifying Leukocyte Functional Heterogeneity in Patients with Early Sepsis Based on Endotoxin Tolerance (2019) (0)
- Smog Signals (2012) (0)
- You Want To Give Me WHAT? (2013) (0)
- Tracheal Aspirate Sequencing Identifies Unique Features of Dysregulated Host Response in SARS-CoV2 Associated Acute Respiratory Distress Syndrome (2021) (0)
- 28: SHORT STATURE IS ASSOCIATED WITH INCREASED RISK OF MORTALITY IN ACUTE RESPIRATORY DISTRESS SYNDROME (2019) (0)
- Metagenomic Sequencing in the ICU for Precision Diagnosis of Critical Infectious Illnesses (2023) (0)
- A Breath of Fresh Alveoli (2012) (0)
- From One Stem Cell to Another (2012) (0)
- Hyperinflammatory ARDS Is Characterized by Interferon-High, Neutrophil-Predominant Inflammation in the Lower Respiratory Tract (2022) (0)
- Plasma TNF-a Levels Are Elevated Early In Acute Lung Injury Prior To Onset Of Respiratory Failure (2011) (0)
- Necrosome Complex Release and Necroinflammation in Hyper-Inflammatory ARDS (2020) (0)
- Absolute Level Versus Rate of Lactate Change in Predicting In-Hospital Mortality in Sepsis (2020) (0)
- Plasma Metabolic Profiles of Hyperinflammatory and Hypoinflammatory ARDS May Implicate Glycolytic Shift (2022) (0)
- Sepsis Phenotyping Using Clinical and Biomarker Data in the ProCESS Randomized Trial (2019) (0)
- Serum Tumor Necrosis Factor Receptor 1 Is Associated with Acute Kidney Injury in Acute Respiratory Distress Syndrome Patients (2019) (0)
- 1 Cigarette smoke exposure worsens acute lung (2018) (0)
- Nicotine in E-cigarette Aerosols Alters Pulmonary Gene Expression, Increases Lung Protein Permeability, and Impairs Virus Clearance During Influenza Infection in Mice (2023) (0)
- Rising PGD Incidence Parallels Increased Recipient Disease Severity (2021) (0)
- Levels Of Plasma Interleukin-8 May Mediate Higher Severity Of Illness In African American Patients With Acute Lung Injury (2012) (0)
- Metabolic signatures of ARDS and ARDS heterogeneity. (2021) (0)
- Ventilatory Ratio is a Valuable Prognostic Indicator in a Representative Observational Cohort of Patients with Acute Respiratory Distress Syndrome (2021) (0)
- CALL FOR PAPERS Translational Research in Acute Lung Injury and Pulmonary Fibrosis Silencing Bruton’s tyrosine kinase in alveolar neutrophils protects mice from LPS/immune complex-induced acute lung injury (2014) (0)
- A Polymorphism In The Duffy Antigen Receptor For Chemokines Gene (Duffy Null State) Predicts Increased Mortality In African Americans With Acute Lung Injury (2010) (0)
- Common Genetic Variants in the Protein C, Endothelial Protein C Receptor and Thrombomodulin Genes Are Associated with Outcomes in Acute Lung Injury. (2009) (0)
- Long Term Mortality In Clinical Acute Lung Injury Is Dramatically Higher Than Hospital Mortality (2012) (0)
- Acute respiratory distress syndrome phenotypes with distinct clinical outcomes in PHARLA trial cohort (2021) (0)
- 493 GREATER PERCEIVED CONTROL OF ASTHMA IS ASSOCIATED WITH DECREASED ASTHMA-RELATED EMERGENCY HEALTH CARE UTILIZATION. (2006) (0)
- 681: PROGNOSTIC VALUE OF PRE-HOSPITAL CRITICAL ILLNESS SCORE COMPARED TO EMERGENCY DEPARTMENT AND INTENSIVE CARE UNIT SCORING SYSTEMS (2012) (0)
- A conserved immune trajectory of recovery in hospitalized COVID-19 patients (2022) (0)
- Revisiting The Acute Lung Injury Score: Prognostic Value For Clinical Outcomes In A Broad Sample Of Patients With Acute Lung Injury (2011) (0)
- Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of SIRS, SOFA, and qSOFA (2020) (0)
- Title Subphenotypes in acute respiratory distress syndrome : latent class analysis of data from two randomised controlled trials (2014) (0)
- NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes (2022) (0)
- Comparison of Clustering Methods for Identifying Heterogeneity of Treatment Effect in Acute Respiratory Distress Syndrome (2021) (0)
- Smoke Exposure and the Acute Respiratory Distress Syndrome. (2015) (0)
- Clinical Evidence of Early Acute Lung Injury Often Precedes the Diagnosis of ALI. (2009) (0)
- Differences in Demographics and the Timing of Treatment of Sepsis Based on Sepsis-2 Versus Sepsis-3 Criteria in the Emergency Department (2019) (0)
- Mesenchymal stem cells for treatment of ARDS: a phase 1 clinical trial (2015) (0)
- Comparison Of Intensive Care Unit And Emergency Department Based Scoring Systems For Prediction Of Mortality In Critically Ill Patients (2012) (0)
- Subphenotypes of frailty in lung transplant candidates. (2023) (0)
- Cigarette Smoking and ARDS After Blunt Trauma (0)
- The authors reply [21] (2007) (0)
- Report of the first seven agents in the I-SPY COVID trial: a phase 2, open label, adaptive platform randomised controlled trial (2023) (0)
- Physiologically Derived Transcriptional Signature of Endotoxin Tolerance Identifies Immune Suppression in Early Sepsis (2020) (0)
- Aerosolized nicotine from e-cigarettes alters gene expression, increases lung protein permeability, and impairs viral clearance in murine influenza infection (2023) (0)
- Cells for Severe Acute Lung Injury Therapeutic Potential of Mesenchymal Stem (2010) (0)
- Latent Class Analysis-Derived Hypoinflammatory and Hyperinflammatory Phenotypes Are Generalisable to Sepsis Patients Requiring Intensive Care (2022) (0)
- Your Cells or Mine? (2012) (0)
- Nonventilatory Treatments for ARDS (2008) (0)
- Prevalence of type-1 interferon autoantibodies in adults with non-COVID-19 acute respiratory failure (2022) (0)
- Another Smoking Gun (2012) (0)
- Corticosteroids in ARDS (2007) (0)
- Division of Allergy, Pulmonary & Critical Care Medicine Newsletter (2016) (0)
- Revisiting the ROSE Trial - Why Did Participants with ARDS Identified as Hispanic/Latino Have Lower Mortality When Randomized to Receive Early Neuromuscular Blockade? (2022) (0)
- From Contagion to Outbreak: Host Susceptibility in Viral Pneumonia (2012) (0)
- Long-Term Ozone and PM 2.5 Exposure Is Positively Associated with Telomere Length in Critically Ill Patients (2019) (0)
- Brother, Can You Spare Some Mitochondria? (2012) (0)
- Title Intensive care unit scoring systems outperform emergency department scoring systems for mortality prediction in critically ill patients : a prospective cohort study (2014) (0)
- Quantitative Severity Scoring of Pulmonary Edema on the Chest Radiograph with the RALE Score May Have Predictive Value for All-Cause 28-Day Mortality in ARDS Patients (2020) (0)
- The authors reply. (2016) (0)
- 28 (2017) (0)
- The authors reply. (2019) (0)
- Patients Point the Way (2012) (0)
- The Hyperinflammatory and Hypoinflammatory Phenotypes Have Divergent Clinical Outcomes in Sepsis and Differential Response to Activated Protein C (2023) (0)
- Cigarette Smoking Is Associated with Clinical and Biological Heterogeneity in Patients with the Acute Respiratory Distress Syndrome (2019) (0)
- The relationship between plasma cystatin C, mortality and acute respiratory distress syndrome subphenotype in the HARP-2 trial (2022) (0)
- Smoking and the risk of acute lung injury in patients undergoing oesophagectomy (2014) (0)
- Antimicrobial Effects of Stem Cells (2013) (0)
- 100 Serial lung ultrasonography in Malawian patients with suspected sepsis and haemodynamic compromise: findings change with intravenous fluid treatment and predict hypoxia (2020) (0)
- Immunosuppression May Modify Performance of Biomarker-Based ARDS Phenotype Classifiers (2022) (0)
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