Casper G. Schalkwijk

Casper G. Schalkwijk's AcademicInfluence.com Rankings

Computer Science

#5767

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#6087

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Artificial Intelligence

#1885

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#1917

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#2897

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#3022

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computer-science Degrees

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Computer Science

Casper G. Schalkwijk's Degrees

PhD Computer Science University of Amsterdam
Masters Artificial Intelligence University of Amsterdam
Bachelors Computer Science University of Amsterdam

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Casper G. Schalkwijk's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) (815)
Diastolic Stiffness of the Failing Diabetic Heart: Importance of Fibrosis, Advanced Glycation End Products, and Myocyte Resting Tension (2008) (658)
Associations of C-reactive protein with measures of obesity, insulin resistance, and subclinical atherosclerosis in healthy, middle-aged women. (1999) (542)
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis. (2002) (444)
Disease variants alter transcription factor levels and methylation of their binding sites (2015) (341)
Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian. (2003) (339)
Identification of context-dependent expression quantitative trait loci in whole blood (2016) (332)
Plasma concentration of C-reactive protein is increased in Type I diabetic patients without clinical macroangiopathy and correlates with markers of endothelial dysfunction: evidence for chronic inflammation (1999) (319)
Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes—the EURODIAB Prospective Complications Study (2005) (269)
Genetic and environmental influences interact with age and sex in shaping the human methylome (2016) (260)
Vascular risk factors and markers of endothelial function as determinants of inflammatory markers in type 1 diabetes: the EURODIAB Prospective Complications Study. (2003) (242)
Humoral markers of inflammation and endothelial dysfunction in relation to adiposity and in vivo insulin action in Pima Indians. (2002) (225)
Obesity-associated low-grade inflammation in type 2 diabetes mellitus: causes and consequences. (2013) (216)
The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases. (2015) (215)
Higher Plasma Levels of Advanced Glycation End Products Are Associated With Incident Cardiovascular Disease and All-Cause Mortality in Type 1 Diabetes (2011) (213)
Methylglyoxal, a highly reactive dicarbonyl compound, in diabetes, its vascular complications and other age-related diseases. (2019) (211)
A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells. (1997) (209)
Cytokine-stimulated secretion of group II phospholipase A2 by rat mesangial cells. Its contribution to arachidonic acid release and prostaglandin synthesis by cultured rat glomerular cells. (1993) (205)
Effects of short‐term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo‐controlled trial (2005) (202)
Diabetes Mellitus Worsens Diastolic Left Ventricular Dysfunction in Aortic Stenosis Through Altered Myocardial Structure and Cardiomyocyte Stiffness (2011) (201)
Overexpression of Glyoxalase-I Reduces Hyperglycemia-induced Levels of Advanced Glycation End Products and Oxidative Stress in Diabetic Rats* (2010) (198)
Long-term exposure to new peritoneal dialysis solutions: Effects on the peritoneal membrane. (2004) (198)
Fructose‐mediated non‐enzymatic glycation: sweet coupling or bad modification (2004) (193)
Vascular complications in diabetes mellitus: the role of endothelial dysfunction. (2005) (188)
Impaired renal function is associated with markers of endothelial dysfunction and increased inflammatory activity. (2003) (186)
Analysis of advanced glycation endproducts in selected food items by ultra-performance liquid chromatography tandem mass spectrometry: Presentation of a dietary AGE database. (2016) (171)
Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress (2010) (170)
Advanced glycation end products and diabetic foot disease (2008) (169)
Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients (2011) (168)
Phospholipase A2 levels in acute chest syndrome of sickle cell disease. (1996) (168)
Citrate anticoagulation abolishes degranulation of polymorphonuclear cells and platelets and reduces oxidative stress during haemodialysis. (2006) (161)
In vivo effects of sex steroids on lymphocyte responsiveness and immunoglobulin levels in humans. (2000) (157)
Blood lipids influence DNA methylation in circulating cells (2016) (156)
Renal Effects of Aliskiren Compared With and in Combination With Irbesartan in Patients With Type 2 Diabetes, Hypertension, and Albuminuria (2009) (153)
Inflammation and premature aging in advanced chronic kidney disease. (2017) (146)
Amadori albumin in type 1 diabetic patients: correlation with markers of endothelial function, association with diabetic nephropathy, and localization in retinal capillaries. (1999) (145)
Parinaric acid as a sensitive fluorescent probe for the determination of lipid peroxidation. (1987) (141)
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits (2018) (139)
Induction of 1,2-Dicarbonyl Compounds, Intermediates in the Formation of Advanced Glycation End-Products, during Heat-Sterilization of Glucose-Based Peritoneal Dialysis Fluids (1999) (137)
Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype. (2014) (136)
Cytokine activation during attacks of the hyperimmunoglobulinemia D and periodic fever syndrome. (1995) (136)
Time course of the antiproteinuric and antihypertensive effects of direct renin inhibition in type 2 diabetes. (2008) (135)
Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology (2012) (134)
Abdominal subcutaneous and visceral adipocyte size, lipolysis and inflammation relate to insulin resistance in male obese humans (2018) (133)
Supplementation of the Pure Flavonoids Epicatechin and Quercetin Affects Some Biomarkers of Endothelial Dysfunction and Inflammation in (Pre)Hypertensive Adults: A Randomized Double-Blind, Placebo-Controlled, Crossover Trial. (2015) (131)
Endothelial Dysfunction and Low-Grade Inflammation Are Associated With Greater Arterial Stiffness Over a 6-Year Period (2011) (130)
Adapted dietary inflammatory index and its association with a summary score for low-grade inflammation and markers of glucose metabolism: the Cohort study on Diabetes and Atherosclerosis Maastricht (CODAM) and the Hoorn study. (2013) (129)
Advanced glycation endproducts and its receptor for advanced glycation endproducts in obesity (2013) (125)
Markers of Endothelial Dysfunction and Inflammation in Type 1 Diabetic Patients With or Without Diabetic Nephropathy Followed for 10 Years (2008) (120)
Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations (2015) (120)
Plasma Advanced Glycation End Products Are Associated With Incident Cardiovascular Events in Individuals With Type 2 Diabetes: A Case-Cohort Study With a Median Follow-up of 10 Years (EPIC-NL) (2014) (120)
N&egr;-(Carboxymethyl)lysine-Receptor for Advanced Glycation End Product Axis Is a Key Modulator of Obesity-Induced Dysregulation of Adipokine Expression and Insulin Resistance (2014) (117)
Measurement of Nε-(Carboxymethyl)lysine and Nε-(Carboxyethyl)lysine in Human Plasma Protein by Stable-Isotope-Dilution Tandem Mass Spectrometry (2004) (117)
Quantification of glyoxal, methylglyoxal and 3-deoxyglucosone in blood and plasma by ultra performance liquid chromatography tandem mass spectrometry: evaluation of blood specimen (2014) (117)
Higher Plasma Soluble Receptor for Advanced Glycation End Products (sRAGE) Levels Are Associated With Incident Cardiovascular Disease and All-Cause Mortality in Type 1 Diabetes (2010) (116)
Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics (2010) (114)
Association between mannose-binding lectin and vascular complications in type 1 diabetes. (2004) (114)
Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes (2013) (113)
Increased accumulation of the glycoxidation product Nepsilon-(carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody. (2004) (112)
Low‐grade inflammation can partly explain the association between the metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease: the CODAM study (2009) (111)
Advanced Glycation End Products Are Associated With Pulse Pressure in Type 1 Diabetes: The EURODIAB Prospective Complications Study (2005) (110)
Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus. (2003) (108)
Plasma asymmetric dimethylarginine (ADMA) concentration is independently associated with carotid intima-media thickness and plasma soluble vascular cell adhesion molecule-1 (sVCAM-1) concentration in patients with mild-to-moderate renal failure. (2005) (107)
Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms (2016) (106)
Endothelial dysfunction in (pre)diabetes: Characteristics, causative mechanisms and pathogenic role in type 2 diabetes (2013) (105)
Current therapeutic interventions in the glycation pathway: evidence from clinical studies (2013) (104)
Plasma levels of advanced glycation endproducts Nε-(carboxymethyl)lysine, Nε-(carboxyethyl)lysine, and pentosidine are not independently associated with cardiovascular disease in individuals with or without type 2 diabetes: the Hoorn and CODAM studies. (2013) (103)
Advanced Glycation End Products in Human Cancer Tissues: Detection of Nε‐(Carboxymethyl)lysine and Argpyrimidine (2005) (102)
Associations of low grade inflammation and endothelial dysfunction with depression – The Maastricht Study (2016) (100)
Long‐term effects of metformin on endothelial function in type 2 diabetes: a randomized controlled trial (2014) (100)
Association of polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating RAGE levels. (2009) (99)
Long-term effects of combined hormone replacement therapy on markers of endothelial function and inflammatory activity in healthy postmenopausal women. (1999) (98)
Interleukin-1β, tumor necrosis factor and forskolin stimulate the synthesis and secretion of group II phospholipase A2 in rat mesangial cells (1991) (97)
Adiponectin is inversely associated with renal function in type 1 diabetic patients. (2006) (95)
Dietary intake of advanced glycation endproducts is associated with higher levels of advanced glycation endproducts in plasma and urine: The CODAM study. (2017) (94)
Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis. (2012) (94)
Altered expression of genes related to blood-retina barrier disruption in streptozotocin-induced diabetes. (2009) (92)
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis (2016) (91)
Impact of metformin versus repaglinide on non-glycaemic cardiovascular risk markers related to inflammation and endothelial dysfunction in non-obese patients with type 2 diabetes. (2008) (91)
Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice (2017) (90)
Development of sulfasalazine resistance in human T cells induces expression of the multidrug resistance transporter ABCG2 (BCRP) and augmented production of TNFα (2004) (89)
Clinical and prognostic value of advanced glycation end-products in chronic heart failure. (2007) (88)
Mannose-binding lectin and mortality in type 2 diabetes. (2006) (85)
Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: a double-blind, randomized, crossover trial. (2016) (84)
Increased levels of Nϵ-(carboxymethyl)lysine and Nϵ-(carboxyethyl)lysine in type 1 diabetic patients with impaired renal function: correlation with markers of endothelial dysfunction (2004) (81)
Endothelial dysfunction and inflammation predict development of diabetic nephropathy in the Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria (IRMA 2) study (2008) (81)
Single Exposure of Mesothelial Cells to Glucose Degradation Products (GDPs) Yields Early Advanced Glycation End-Products (AGEs) and a Proinflammatory Response (2003) (80)
Effects of rosuvastatin and atorvastatin on glycaemic control in Type 2 diabetes—the CORALL study (2012) (80)
Soluble vascular cell adhesion molecule-1 and soluble E-selectin are associated with micro- and macrovascular complications in Type 1 diabetic patients. (2006) (80)
Endoplasmic reticulum stress-induced apoptosis in the development of diabetes: is there a role for adipose tissue and liver? (2009) (79)
Plasmalogen biosynthesis in peroxisomal disorders: fatty alcohol versus alkylglycerol precursors. (1988) (77)
Irbesartan Treatment Reduces Biomarkers of Inflammatory Activity in Patients With Type 2 Diabetes and Microalbuminuria (2006) (76)
Contribution of lactate buffer, glucose and glucose degradation products to peritoneal injury in vivo. (2003) (76)
MicroRNA-126 and micro-/macrovascular complications of type 1 diabetes in the EURODIAB Prospective Complications Study (2017) (75)
Skewed X-inactivation is common in the general female population (2018) (75)
Iron Metabolism Is Associated With Adipocyte Insulin Resistance and Plasma Adiponectin (2013) (75)
Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease. (2016) (75)
Heat‐shock protein 27 is a major methylglyoxal‐modified protein in endothelial cells (2006) (72)
C-reactive protein in type 1 diabetes and its relationship to coronary artery calcification. (2002) (71)
Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina (2007) (71)
Studies on the acyl-chain selectivity of cellular phospholipases A2. (1990) (70)
L(+) and D(−) Lactate Are Increased in Plasma and Urine Samples of Type 2 Diabetes as Measured by a Simultaneous Quantification of L(+) and D(−) Lactate by Reversed-Phase Liquid Chromatography Tandem Mass Spectrometry (2012) (70)
The cross‐sectional association between insulin resistance and circulating complement C3 is partly explained by plasma alanine aminotransferase, independent of central obesity and general inflammation (the CODAM study) (2011) (70)
Severe Hypoglycemia and Cardiovascular Disease Incidence in Type 1 Diabetes (2012) (68)
Levels of soluble receptor for AGE are cross-sectionally associated with cardiovascular disease in type 1 diabetes, and this association is partially mediated by endothelial and renal dysfunction and by low-grade inflammation: the EURODIAB Prospective Complications Study (2009) (68)
Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis. (2006) (68)
Complement Factor 3 Is Associated With Insulin Resistance and With Incident Type 2 Diabetes Over a 7-Year Follow-up Period: The CODAM Study (2014) (67)
Interleukin-1 beta- and forskolin-induced synthesis and secretion of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by transforming growth factor-beta 2. (1992) (67)
Interleukin‐1β and transforming growth factor‐β2 enhance cytosolic high‐molecular‐mass phospholipase A2 activity and induce prostaglandin E2 formation in rat mesangial cells (1992) (66)
Fish consumption in healthy adults is associated with decreased circulating biomarkers of endothelial dysfunction and inflammation during a 6-year follow-up. (2011) (66)
Serum Heat Shock Protein 27 and Diabetes Complications in the EURODIAB Prospective Complications Study (2008) (66)
Circulating classical monocytes are associated with CD11c+ macrophages in human visceral adipose tissue (2017) (65)
High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling. (2017) (65)
Measurement of pentosidine in human plasma protein by a single-column high-performance liquid chromatography method with fluorescence detection. (2009) (64)
Novel Biomarkers to Improve the Prediction of Cardiovascular Event Risk in Type 2 Diabetes Mellitus (2016) (62)
Vascular AGE-ing by methylglyoxal: the past, the present and the future (2015) (61)
Epidermal growth factor (EGF) induces serine phosphorylation-dependent activation and calcium-dependent translocation of the cytosolic phospholipase A2. (1995) (61)
Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians. (2007) (60)
Cytokine- and forskolin-induced synthesis of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by dexamethasone. (1991) (59)
The role of advanced glycation end-products and their receptor on outcome in heart failure patients with preserved and reduced ejection fraction. (2012) (59)
Vitamin E inhibits lipid peroxidation-induced adhesion molecule expression in endothelial cells and decreases soluble cell adhesion molecules in healthy subjects. (2003) (58)
Obesity-induced chronic inflammation in high fat diet challenged C57BL/6J mice is associated with acceleration of age-dependent renal amyloidosis (2015) (58)
Reversal of Hypoxia in Murine Atherosclerosis Prevents Necrotic Core Expansion by Enhancing Efferocytosis (2014) (57)
Maximal epidermal growth-factor-induced cytosolic phospholipase A2 activation in vivo requires phosphorylation followed by an increased intracellular calcium concentration. (1996) (57)
A healthy diet is associated with less endothelial dysfunction and less low-grade inflammation over a 7-year period in adults at risk of cardiovascular disease. (2015) (57)
Effects of tumour necrosis factor-alpha in the human forearm: blood flow and endothelin-1 release. (2002) (57)
Capillary Rarefaction Associates with Albuminuria: The Maastricht Study. (2016) (56)
Endothelial dysfunction is associated with a greater depressive symptom score in a general elderly population: the Hoorn Study (2013) (56)
Maternal diet, gestational weight gain, and inflammatory markers during pregnancy (2016) (56)
The association between the metabolic syndrome and alanine amino transferase is mediated by insulin resistance via related metabolic intermediates (the Cohort on Diabetes and Atherosclerosis Maastricht [CODAM] study). (2011) (55)
Advanced Glycation End Products Accumulate in Vascular Smooth Muscle and Modify Vascular but Not Ventricular Properties in Elderly Hypertensive Canines (2008) (55)
Association of Type D personality with increased vulnerability to depression: Is there a role for inflammation or endothelial dysfunction? - The Maastricht Study. (2016) (55)
Delayed Intervention With Pyridoxamine Improves Metabolic Function and Prevents Adipose Tissue Inflammation and Insulin Resistance in High-Fat Diet–Induced Obese Mice (2015) (55)
Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease in Individuals With Type 1 Diabetes: A 12-Year Follow-up Study (2017) (54)
Associations of advanced glycation end-products with cognitive functions in individuals with and without type 2 diabetes: the maastricht study. (2015) (54)
Markers of inflammation and endothelial dysfunction are associated with incident cardiovascular disease, all-cause mortality, and progression of coronary calcification in type 2 diabetic patients with microalbuminuria. (2016) (54)
Aggressive antihypertensive therapy based on hydrochlorothiazide, candesartan or lisinopril as initial choice in hypertensive type II diabetic individuals: effects on albumin excretion, endothelial function and inflammation in a double-blind, randomized clinical trial (2005) (54)
Indian Asian men have less peripheral arterial disease than European men for equivalent levels of coronary disease. (2007) (53)
Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis (2020) (53)
Effects of Transdermal and Oral Oestrogen Replacement Therapy on C-Reactive Protein Levels in Postmenopausal Women: A Randomised, Placebo-Controlled Trial (2002) (53)
Impaired HDL cholesterol efflux in metabolic syndrome is unrelated to glucose tolerance status: the CODAM study (2016) (53)
Post–Glucose Load Plasma α-Dicarbonyl Concentrations Are Increased in Individuals With Impaired Glucose Metabolism and Type 2 Diabetes: The CODAM Study (2015) (53)
Diet-induced weight loss improves not only cardiometabolic risk markers but also markers of vascular function: a randomized controlled trial in abdominally obese men. (2017) (53)
Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease and Mortality in Individuals With Type 2 Diabetes (2018) (52)
Methylglyoxal-derived stress: An emerging biological factor involved in the onset and progression of cancer. (2017) (52)
Circulating and urinary transforming growth factor beta1, Amadori albumin, and complications of type 1 diabetes: the EURODIAB prospective complications study. (2002) (50)
Amadori‐albumin correlates with microvascular complications and precedes nephropathy in type 1 diabetic patients (2002) (50)
Skin-autofluorescence, a measure of tissue advanced glycation end-products (AGEs), is related to diastolic function in dialysis patients. (2008) (50)
Plasma levels of advanced glycation endproducts are associated with type 1 diabetes and coronary artery calcification (2013) (50)
Functioning of oxidative phosphorylation in liver mitochondria of high-fat diet fed rats. (2007) (50)
Extracellular overhydration linked with endothelial dysfunction in the context of inflammation in haemodialysis dependent chronic kidney disease (2017) (49)
Structural and enzymological properties of cellular phospholipases A2. (1990) (49)
Protein-bound uraemic toxins, dicarbonyl stress and advanced glycation end products in conventional and extended haemodialysis and haemodiafiltration. (2015) (49)
The Role of Hyperglycemia, Insulin Resistance, and Blood Pressure in Diabetes-Associated Differences in Cognitive Performance—The Maastricht Study (2017) (48)
Plasma advanced glycation end-products and skin autofluorescence are increased in COPD (2013) (48)
Unhealthy dietary patterns associated with inflammation and endothelial dysfunction in type 1 diabetes: the EURODIAB study. (2013) (48)
Plasma matrix metalloproteinases are associated with incident cardiovascular disease and all-cause mortality in patients with type 1 diabetes: a 12-year follow-up study (2017) (48)
Advanced glycation end products in human cancer tissues: detection of Nepsilon-(carboxymethyl)lysine and argpyrimidine. (2005) (48)
The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1 (2013) (47)
Impact of type 2 diabetes and the metabolic syndrome on myocardial structure and microvasculature of men with coronary artery disease (2011) (47)
Methylglyoxal-Derived Advanced Glycation Endproducts in Multiple Sclerosis (2017) (47)
Amadori Albumin and Advanced Glycation End-Product Formation in Peritoneal Dialysis using Icodextrin (2001) (47)
Diastolic Dysfunction of Aging Is Independent of Myocardial Structure but Associated with Plasma Advanced Glycation End-Product Levels (2012) (46)
Iron metabolism is prospectively associated with insulin resistance and glucose intolerance over a 7-year follow-up period: the CODAM study (2015) (46)
Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study (2015) (46)
Low-grade inflammation and insulin resistance independently explain substantial parts of the association between body fat and serum C3: the CODAM study. (2012) (45)
Improved biocompatibility of bicarbonate/lactate-buffered PDF is not related to pH. (2006) (45)
N ϵ-(carboxymethyl)lysine, N ϵ-(carboxyethyl)lysine and vascular cell adhesion molecule-1 (VCAM-1) in relation to peritoneal glucose prescription and residual renal function; a study in peritoneal dialysis patients (2004) (44)
Distinct associations of complement C3a and its precursor C3 with atherosclerosis and cardiovascular disease (2014) (44)
Interleukin‐1β‐induced cytosolic phospholipase A2 activity and protein synthesis is blocked by dexamethasone in rat mesangial cells (1993) (43)
Modulation of insulin action by advanced glycation endproducts: a new player in the field. (2008) (43)
Dose-Finding Study of the Multitargeted Tyrosine Kinase Inhibitor SU6668 in Patients with Advanced Malignancies (2005) (43)
Association of plasma sRAGE, but not esRAGE with lung function impairment in COPD (2014) (43)
Effect of Benfotiamine on Advanced Glycation Endproducts and Markers of Endothelial Dysfunction and Inflammation in Diabetic Nephropathy (2012) (43)
Measurement of Nepsilon-(carboxymethyl)lysine and Nepsilon-(carboxyethyl)lysine in human plasma protein by stable-isotope-dilution tandem mass spectrometry. (2004) (43)
Skin Autofluorescence and Pentosidine Are Associated With Aortic Stiffening: The Maastricht Study (2016) (43)
Abdominal Fat Mass Is Associated With Adaptive Immune Activation: The CODAM Study (2011) (43)
Increased α3-fucosylation of α1-acid glycoprotein in Type I diabetic patients is related to vascular function (2001) (42)
Quantification of dicarbonyl compounds in commonly consumed foods and drinks; presentation of a food composition database for dicarbonyls. (2021) (42)
Plasma homocysteine is weakly correlated with plasma endothelin and von Willebrand factor but not with endothelium-dependent vasodilatation in healthy postmenopausal women. (1999) (41)
Plasma levels of advanced glycation end products are associated with haemolysis‐related organ complications in sickle cell patients (2010) (41)
Stability of soluble adhesion molecules, selectins, and C-reactive protein at various temperatures: implications for epidemiological and large-scale clinical studies. (2007) (40)
Hypertension Is a Conditional Factor for the Development of Cardiac Hypertrophy in Type 2 Diabetic Mice (2014) (40)
ACE‐inhibition modulates some endothelial functions in healthy subjects and in normotensive type 1 diabetic patients (2000) (40)
Reduced 1,2-Dicarbonyl Compounds in Bicarbonate/Lactate-Buffered Peritoneal Dialysis (PD) Fluids and PD Fluids Based on Glucose Polymers or Amino Acids (2000) (40)
BclI glucocorticoid receptor polymorphism is associated with greater body fatness: the Hoorn and CODAM studies. (2013) (39)
Renal inflammatory markers during the onset of hypertension in spontaneously hypertensive rats (2014) (39)
DNA methylation signatures of educational attainment (2018) (39)
Targeting hyperglycaemia with either metformin or repaglinide in non‐obese patients with type 2 diabetes: results from a randomized crossover trial (2007) (39)
Increased levels of N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine in type 1 diabetic patients with impaired renal function: correlation with markers of endothelial dysfunction. (2004) (38)
Platelet and leukocyte activation, atherosclerosis and inflammation in European and South Asian men (2007) (38)
The EURODIAB Prospective Complications Study (2012) (38)
Methylglyoxal and glyoxalase I in atherosclerosis. (2014) (38)
N(omega)-(carboxymethyl)lysine depositions in human aortic heart valves: similarities with atherosclerotic blood vessels. (2004) (37)
ANTI‐HSP60 and ANTI‐HSP70 antibody levels and micro/ macrovascular complications in type 1 diabetes: the EURODIAB Study (2009) (37)
Immunopathological changes in a uraemic rat model for peritoneal dialysis. (2005) (37)
Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals. (2019) (36)
Optimal antiproteinuric dose of aliskiren in type 2 diabetes mellitus: a randomised crossover trial (2010) (36)
Low 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 levels are independently associated with macroalbuminuria, but not with retinopathy and macrovascular disease in type 1 diabetes: the EURODIAB prospective complications study (2015) (36)
Human plasma complement C3 is independently associated with coronary heart disease, but only in heavy smokers (the CODAM study). (2012) (36)
Palmitate and oleate have distinct effects on the inflammatory phenotype of human endothelial cells. (2007) (35)
Reducing sitting time versus adding exercise: differential effects on biomarkers of endothelial dysfunction and metabolic risk (2018) (35)
Modulation of plasma endothelin levels by the menstrual cycle. (2000) (35)
Distinct Associations of HbA1c and the Urinary Excretion of Pentosidine, an Advanced Glycosylation End-product, with Markers of Endothelial Function in Insulin-dependent Diabetes mellitus (1998) (35)
Activated complement factor 3 is associated with liver fat and liver enzymes: the CODAM study (2013) (35)
EURODIAB Prospective Complications Study Group. Adiponectin is inversely associated with renal function in type 1 diabetic patients. (2006) (34)
Homocysteine‐lowering treatment with folic acid plus vitamin B6 lowers urinary albumin excretion but not plasma markers of endothelial function or C‐reactive protein: further analysis of secondary end‐points of a randomized clinical trial (2003) (34)
Protein-Bound Plasma N&egr;-(Carboxymethyl)lysine Is Inversely Associated With Central Obesity and Inflammation and Significantly Explain a Part of the Central Obesity–Related Increase in Inflammation: The Hoorn and CODAM Studies (2015) (34)
Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer (2019) (34)
Quercetin, but Not Epicatechin, Decreases Plasma Concentrations of Methylglyoxal in Adults in a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial with Pure Flavonoids. (2018) (34)
Multiple Inflammatory Biomarker Detection in a Prospective Cohort Study: A Cross-Validation between Well-Established Single-Biomarker Techniques and an Electrochemiluminescense-Based Multi-Array Platform (2013) (34)
Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly: the Hoorn Study (2012) (33)
Beneficial effects of aminoguanidine on peritoneal microcirculation and tissue remodelling in a rat model of PD. (2005) (33)
Discriminatory ability of simple OGTT-based beta cell function indices for prediction of prediabetes and type 2 diabetes: the CODAM study (2016) (33)
Associations Between the Ankle-Brachial Index and Cardiovascular and All-Cause Mortality Are Similar in Individuals Without and With Type 2 Diabetes (2012) (32)
Effects of transdermal and oral postmenopausal hormone therapy on vascular function: a randomized, placebo-controlled study in healthy postmenopausal women (2005) (32)
Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults (2019) (32)
Effect of atorvastatin on C-reactive protein and benefits for cardiovascular disease in patients with type 2 diabetes: analyses from the Collaborative Atorvastatin Diabetes Trial (2015) (32)
Effects of sodium and potassium supplementation on endothelial function: a fully controlled dietary intervention study (2015) (32)
Pathophysiological role of Amadori-glycated proteins in diabetic microangiopathy. (2002) (31)
Black Tea Increases Circulating Endothelial Progenitor Cells and Improves Flow Mediated Dilatation Counteracting Deleterious Effects from a Fat Load in Hypertensive Patients: A Randomized Controlled Study (2016) (31)
TNF-receptor levels in preeclampsia--results of a longitudinal study in high-risk women. (2003) (31)
Plasma Levels of AGE Peptides in Type 1 Diabetic Patients Are Associated with Serum Creatinine and Not with Albumin Excretion Rate: Possible Role of AGE Peptide‐Associated Endothelial Dysfunction (2005) (31)
Methylglyoxal stress, the glyoxalase system, and diabetic chronic kidney disease (2019) (31)
Phospholipase A2 is a circulating mediator in typhoid fever. (1995) (30)
Higher plasma high-mobility group box 1 levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12 year follow-up study (2012) (30)
Interaction of Nepsilon(carboxymethyl)lysine- and methylglyoxal-modified albumin with endothelial cells and macrophages. Splice variants of RAGE may limit the responsiveness of human endothelial cells to AGEs. (2006) (30)
Nepsilon-(carboxymethyl)lysine, Nepsilon-(carboxyethyl)lysine and vascular cell adhesion molecule-1 (VCAM-1) in relation to peritoneal glucose prescription and residual renal function; a study in peritoneal dialysis patients. (2004) (30)
The alternative complement pathway is longitudinally associated with adverse cardiovascular outcomes (2016) (30)
Dysfunctional adipose tissue and low-grade inflammation in the management of the metabolic syndrome: current practices and future advances (2016) (30)
Dietary advanced glycation endproducts (AGEs) increase their concentration in plasma and tissues, result in inflammation and modulate gut microbial composition in mice; evidence for reversibility. (2021) (30)
Circulating matrix metalloproteinases are associated with arterial stiffness in patients with type 1 diabetes: pooled analysis of three cohort studies (2017) (30)
Angiotensin II blockade is associated with decreased plasma leukocyte adhesion molecule levels in diabetic nephropathy. (2000) (30)
Biomarkers for post thrombotic syndrome: a case-control study. (2014) (30)
Mild Oxidative Damage in the Diabetic Rat Heart Is Attenuated by Glyoxalase-1 Overexpression (2013) (30)
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour (2021) (29)
A potential role for glycated cross‐links in abdominal aortic aneurysm disease (2017) (29)
Levels and localization of group II phospholipase A2 and annexin I in interleukin- and dexamethasone-treated rat mesangial cells: evidence against annexin mediation of the dexamethasone-induced inhibition of group II phospholipases A2. (1994) (28)
Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies (2009) (28)
Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: association study in 2000 Dutch Caucasians. (2008) (28)
Methylglyoxal-Derived Advanced Glycation Endproducts Accumulate in Multiple Sclerosis Lesions (2019) (27)
Energy restriction and Roux-en-Y gastric bypass reduce postprandial α-dicarbonyl stress in obese women with type 2 diabetes (2016) (27)
The association between the −374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: the Hoorn and CoDAM studies (2010) (27)
Impaired microcirculatory perfusion in a rat model of cardiopulmonary bypass: the role of hemodilution. (2016) (27)
Increased Nepsilon-(carboxymethyl)-lysine levels in cerebral blood vessels of diabetic patients and in a (streptozotocin-treated) rat model of diabetes mellitus. (2008) (26)
Alcohol and red wine consumption, but not fruit, vegetables, fish or dairy products, are associated with less endothelial dysfunction and less low-grade inflammation: the Hoorn Study (2017) (26)
Advanced Glycation End Product (AGE) Accumulation in the Skin is Associated with Depression: The Maastricht Study (2017) (26)
Up-regulation of the complement system in subcutaneous adipocytes from nonobese, hypertriglyceridemic subjects is associated with adipocyte insulin resistance. (2012) (26)
Intimal and medial calcification in relation to cardiovascular risk factors (2020) (26)
Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease (2019) (26)
The induction of cellular group II phospholipase A2 by cytokines and its prevention by dexamethasone. (1992) (25)
Phospholipase A 2 Levels in Acute Chest Syndrome of Sickle Cell Disease (2002) (25)
Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans (2019) (25)
Independent tissue contributors to obesity-associated insulin resistance. (2017) (25)
Atrial fibrillation coincides with the advanced glycation end product N(ε)-(carboxymethyl)lysine in the atrium. (2015) (25)
Dietary intake of advanced glycation end products (AGEs) and changes in body weight in European adults (2019) (25)
The ATF6-Met[67]Val Substitution Is Associated With Increased Plasma Cholesterol Levels (2009) (24)
Effects of fructose restriction on liver steatosis (FRUITLESS); a double-blind randomized controlled trial (2020) (24)
Levels of NT-proBNP, markers of low-grade inflammation, and endothelial dysfunction during spironolactone treatment in patients with diabetic kidney disease (2013) (24)
The cross-sectional association between uric acid and atherosclerosis and the role of low-grade inflammation: the CODAM study. (2014) (24)
Increased alpha3-fucosylation of alpha1-acid glycoprotein in Type I diabetic patients is related to vascular function. (2001) (24)
The association between the metabolic syndrome and peripheral, but not coronary, artery disease is partly mediated by endothelial dysfunction: the CODAM study (2011) (24)
Nɛ‐(Carboxymethyl)lysine during the Early Development of Hypertension (2008) (24)
Association of common gene variants in glucokinase regulatory protein with cardiorenal disease: A systematic review and meta-analysis (2018) (23)
Specific Local Cardiovascular Changes of Nɛ-(Carboxymethyl)lysine, Vascular Endothelial Growth Factor, and Smad2 in the Developing Embryos Coincide With Maternal Diabetes–Induced Congenital Heart Defects (2009) (23)
Nitric Oxide Dysregulation in Patients With Heart Failure: The Association of Depressive Symptoms With L-Arginine, Asymmetric Dimethylarginine, Symmetric Dimethylarginine, and Isoprostane (2015) (23)
Effects of dexamethasone and transforming growth factor-beta 2 on group II phospholipase A2 mRNA and activity levels in interleukin 1 beta- and forskolin-stimulated mesangial cells. (1996) (23)
Advanced glycation end‐products, anti‐hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction (2010) (23)
Higher central fat mass and lower peripheral lean mass are independent determinants of endothelial dysfunction in the elderly: the Hoorn study. (2014) (22)
Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity (2016) (22)
Complement activation products C5a and sC5b-9 are associated with low-grade inflammation and endothelial dysfunction, but not with atherosclerosis in a cross-sectional analysis: the CODAM study. (2014) (22)
Patients with aldolase B deficiency are characterized by an increased intrahepatic triglyceride content. (2019) (22)
Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab. (2020) (22)
Systemic stiffening of mouse tail tendon is related to dietary advanced glycation end products but not high-fat diet or cholesterol. (2014) (22)
The effect of calcium dobesilate on vascular endothelial function, blood pressure, and markers of oxidation in obese male smokers: a placebo-controlled randomised clinical trial. (2003) (22)
Advanced glycation end-product peptides are associated with impaired renal function, but not with biochemical markers of endothelial dysfunction and inflammation, in non-diabetic individuals. (2006) (21)
Microvascular dysfunction is associated with worse cognitive performance: the Maastricht study (2019) (21)
A linear mixed-model approach to study multivariate gene–environment interactions (2018) (21)
TNF-receptor levels in preeclampsia—results of a longitudinal study in high-risk women (2005) (21)
Higher dietary salt intake is associated with microalbuminuria, but not with retinopathy in individuals with type 1 diabetes: the EURODIAB Prospective Complications Study (2014) (21)
Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study (2019) (21)
Anti–Heat Shock Protein 27 Antibody Levels and Diabetes Complications in the EURODIAB Study (2009) (21)
Effect of methylglyoxal on the physico-chemical and biological properties of low-density lipoprotein. (1998) (21)
Type 2 diabetes is not associated with an altered plaque phenotype among patients undergoing carotid revascularization. A histological analysis of 1455 carotid plaques. (2014) (21)
Associations of Arterial Stiffness With Cognitive Performance, and the Role of Microvascular Dysfunction (2020) (21)
Continuing smoking between adolescence and young adulthood is associated with higher arterial stiffness in young adults: the Northern Ireland Young Hearts Project (2011) (21)
An advanced glycation endproduct (AGE)‐rich diet promotes accumulation of AGEs in Achilles tendon (2017) (20)
Patient characteristics rather than the type of dialyser predict the variability of endothelial derived surface molecules in chronic haemodialysis patients. (2005) (20)
Glyoxalase 1 overexpression does not affect atherosclerotic lesion size and severity in ApoE-/- mice with or without diabetes. (2014) (20)
Early Glycated Albumin, but Not Advanced Glycated Albumin, Methylglyoxal, or 3-Deoxyglucosone Increases the Expression of Pai-1 in Human Peritoneal Mesothelial Cells (2001) (20)
Microvascular Dysfunction Is Associated With Worse Cognitive Performance: The Maastricht Study. (2019) (20)
Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes (2018) (20)
Higher plasma soluble receptor for advanced glycation endproducts (sRAGE) levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-yr follow-up study (2010) (20)
High dietary glycemic load is associated with higher concentrations of urinary advanced glycation endproducts: the Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study. (2019) (19)
Postprandial Glucose Spikes, an Important Contributor to Cardiovascular Disease in Diabetes? (2020) (19)
Hypothesis-free identification of modulators of genetic risk factors (2015) (19)
Biomarkers of inflammation and endothelial dysfunction as predictors of pulse pressure and incident hypertension in type 1 diabetes: a 20 year life-course study in an inception cohort (2017) (19)
Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes. (2011) (19)
NH2-Terminal Probrain Natriuretic Peptide Is Associated With Diabetes Complications in the EURODIAB Prospective Complications Study (2012) (19)
A Control Systems Approach to Quantify Wall Shear Stress Normalization by Flow-Mediated Dilation in the Brachial Artery (2015) (19)
The association of hyperglycaemia and insulin resistance with incident depressive symptoms over 4 years of follow-up: The Maastricht Study (2020) (19)
Plasma PAI-1 levels are independently related to fatty liver and hypertriglyceridemia in familial combined hyperlipidemia, involvement of apolipoprotein E. (2008) (18)
More Fibrosis and Thrombotic Complications but Similar Expression Patterns of Markers for Coagulation and Inflammation in Symptomatic Plaques from DM2 Patients (2004) (18)
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS (2022) (18)
Antiangiogenic factors and maternal hemodynamics during intensive hemodialysis in pregnancy (2013) (18)
Calibrated integrated backscatter and myocardial fibrosis in patients undergoing cardiac surgery (2015) (18)
RAGE deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in Western type diet-fed Ldlr−/− mice (2018) (18)
PAI-1 inhibition in obesity and the metabolic syndrome: A promising therapeutic strategy (2006) (18)
Microvascular Phenotyping in the Maastricht Study: Design and Main Findings, 2010–2018 (2020) (18)
Depression and markers of inflammation as predictors of all-cause mortality in heart failure (2016) (18)
Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima–Media Thickness: The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study (2016) (17)
Bone markers and cardiovascular risk in type 2 diabetes patients (2018) (17)
Receptor for Advanced Glycation End Product Polymorphisms and Type 2 Diabetes (2008) (17)
Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects (2018) (16)
A comparison of dicarbonyl stress and advanced glycation endproducts in lifelong endurance athletes vs. sedentary controls. (2017) (16)
Distinct accumulation patterns of soluble forms of E-selectin, VCAM-1 and ICAM-1 upon infusion of TNFα in tumor patients (2003) (15)
Vitreous advanced glycation endproducts and α-dicarbonyls in retinal detachment patients with type 2 diabetes mellitus and non-diabetic controls (2017) (15)
Raloxifene, conjugated oestrogen and endothelial function in postmenopausal women (2003) (15)
The Course of Skin and Serum Biomarkers of Advanced Glycation Endproducts and Its Association with Oxidative Stress, Inflammation, Disease Severity, and Mortality during ICU Admission in Critically Ill Patients: Results from a Prospective Pilot Study (2016) (15)
Complement C3 and C4, but not their regulators or activated products, are associated with incident metabolic syndrome: the CODAM study (2018) (15)
A Common Gene Variant in Glucokinase Regulatory Protein Interacts With Glucose Metabolism on Diabetic Dyslipidemia: the Combined CODAM and Hoorn Studies (2016) (15)
HDL cholesterol efflux capacity and cholesteryl ester transfer are associated with body mass, but are not changed by diet-induced weight loss: A randomized trial in abdominally obese men. (2018) (15)
The tumour suppressor CDKN2A/p16INK4a regulates adipogenesis and bone marrow-dependent development of perivascular adipose tissue (2017) (15)
Methylglyoxal and Methylglyoxal‐arginine Adducts Do Not Directly Inhibit Endothelial Nitric Oxide Synthase (2008) (14)
Association of tear fluid amyloid and tau levels with disease severity and neurodegeneration (2021) (14)
Hyperglycemia Is the Main Mediator of Prediabetes- and Type 2 Diabetes–Associated Impairment of Microvascular Function: The Maastricht Study (2017) (14)
Serum high-mobility group box-1 levels are positively associated with micro- and macroalbuminuria but not with cardiovascular disease in type 1 diabetes: the EURODIAB Prospective Complications Study. (2012) (14)
Cardiometabolic risk factors as determinants of peripheral nerve function: the Maastricht Study (2020) (14)
Erratum to: “Heat‐shock protein 27 is a major methylglyoxal‐modified protein in endothelial cells” [FEBS Lett. 580 (2006) 1565–1570] (2006) (14)
High-density lipoprotein cholesterol efflux capacity is not associated with atherosclerosis and prevalence of cardiovascular outcome: The CODAM study. (2019) (14)
“NEPP” Peritoneal Dialysis Regimen Has Beneficial Effects on Plasma CEL and 3-DG, But Not Pentosidine, CML, and MGO (2012) (14)
A characterization of cis- and trans-heritability of RNA-Seq-based gene expression (2019) (14)
Subclinical inflammation during third trimester of pregnancy was not associated with markers of the metabolic syndrome in young adult offspring (2014) (13)
BclI glucocorticoid receptor polymorphism in relation to cardiovascular variables: the Hoorn and CODAM studies. (2015) (13)
Advanced Glycation Endproducts Are Increased in the Animal Model of Multiple Sclerosis but Cannot Be Reduced by Pyridoxamine Treatment or Glyoxalase 1 Overexpression (2018) (13)
No increase in C-reactive protein levels during intranasal compared to oral hormone therapy in healthy post-menopausal women. (2006) (13)
Diverging effects of diabetes mellitus in patients with peripheral artery disease and abdominal aortic aneurysm and the role of advanced glycation end-products: ARTERY study — protocol for a multicentre cross-sectional study (2017) (13)
Classical Pathway of Complement Activation: Longitudinal Associations of C1q and C1-INH With Cardiovascular Outcomes The CODAM Study (Cohort on Diabetes and Atherosclerosis Maastricht)—Brief Report (2018) (13)
Associations between advanced glycation endproducts and matrix metalloproteinases and its inhibitor in individuals with type 1 diabetes. (2018) (13)
The endothelial function biomarker soluble E‐selectin is associated with nonalcoholic fatty liver disease (2020) (12)
Influence of Icodextrin on Plasma and Dialysate Levels of N∊-(Carboxymethyl)Lysine and N∊-(Carboxyethyl)Lysine (2005) (12)
Serum advanced glycation endproducts are associated with left ventricular dysfunction in normal glucose metabolism but not in type 2 diabetes: The Hoorn Study (2016) (12)
Endothelial dysfunction and low-grade inflammation in the transition to renal replacement therapy (2019) (12)
Hepatic Fat Content and Liver Enzymes Are Associated with Circulating Free and Protein-Bound Advanced Glycation End Products, Which Are Associated with Low-Grade Inflammation: The CODAM Study (2019) (12)
High density lipoproteins exert pro-inflammatory effects on macrophages via passive cholesterol depletion and PKC-NF-kB/STAT1-IRF1 signaling. (2017) (12)
Prospective associations of dietary carbohydrate, fat, and protein intake with β-cell function in the CODAM study (2018) (11)
Aberration in de novo ether lipid biosynthesis in peroxisomal disorders. (1988) (11)
Purification and Characterization of Ca2+-Dependent Phospholipases A2from Rat Kidney (1996) (11)
Longitudinal associations of the alternative and terminal pathways of complement activation with adiposity: The CODAM study. (2017) (11)
Myocardial infarction induces atrial inflammation that can be prevented by C1-esterase inhibitor (2016) (11)
Refining Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Genetic Loci by Integrating Summary Data From Genome-wide Association, Gene Expression, and DNA Methylation Studies (2020) (11)
Higher Plasma Concentrations of the Methylglyoxal Metabolite D-lactate are Independently Associated with Insulin Resistance: The CODAM Study (2014) (11)
Irreversible Renal Damage after Transient Renin-Angiotensin System Stimulation: Involvement of an AT1-Receptor Mediated Immune Response (2013) (11)
Fasting and post-oral-glucose-load levels of methylglyoxal are associated with microvascular, but not macrovascular, disease in individuals with and without (pre)diabetes: The Maastricht Study. (2020) (11)
In vitro and in vivo models for peritonitis demonstrate unchanged neutrophil migration after exposure to dialysis fluids. (2004) (11)
Therapeutic Interventions in the Glyc(oxid)ation Pathway (2007) (11)
Higher habitual intake of dietary dicarbonyls is associated with higher corresponding plasma dicarbonyl concentrations and skin autofluorescence: The Maastricht Study. (2021) (10)
The Nε-(carboxymethyl)lysine–RAGE axis: putative implications for the pathogenesis of obesity-related complications (2010) (10)
Complement c3 is inversely associated with habitual intake of provitamin A but not with dietary fat, fatty acids, or vitamin E in middle-aged to older white adults and positively associated with intake of retinol in middle-aged to older white women. (2014) (10)
Low-grade inflammation and endothelial dysfunction explain the association between retinopathy and left ventricular ejection fraction in men: an 8-year follow-up of the Hoorn Study. (2014) (10)
Effect of HMR 3339, a novel selective estrogen receptor modulator, on C-reactive protein levels in healthy postmenopausal women. (2004) (10)
X-linked adrenoleukodystrophy: Identification of the primary defect at the level of a deficient peroxisomal very long chain fatty acyl-CoA synthetase using a newly developed method for the isolation of peroxisomes from skin fibroblasts (1988) (10)
Influence of Different Haemodialysis Modalities on AGE Peptide Levels: Intradialytic versus Long-Term Results (2005) (10)
The effect of Mindfulness-Based Stress Reduction on wound healing: a preliminary study (2018) (10)
Dietary intake of advanced glycation endproducts and risk of hepatobiliary cancers: A multinational cohort study (2021) (9)
Sedentary behaviour and physical activity are associated with biomarkers of endothelial dysfunction and low-grade inflammation—relevance for (pre)diabetes: The Maastricht Study (2022) (9)
Regional collagen turnover and composition of the human patellar tendon. (2020) (9)
Dietary proteins improve endothelial function under fasting conditions but not in the postprandial state, with no effects on markers of low-grade inflammation (2015) (9)
Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial. (2011) (9)
Contribution of Liver Fat to Weight Loss-Induced Changes in Serum Hepatokines: A Randomized Controlled Trial. (2019) (9)
Circulating Advanced Glycation Endproducts and Long-Term Risk of Cardiovascular Mortality in Kidney Transplant Recipients. (2019) (9)
The detection of multimeric forms of phospholipase A2 upon sodium dodecylsulfate-polyacrylamide electrophoresis. (1991) (9)
NK cells in human visceral adipose tissue contribute to obesity‐associated insulin resistance through low‐grade inflammation (2020) (8)
The Effect of Sulforaphane on Glyoxalase I Expression and Activity in Peripheral Blood Mononuclear Cells (2018) (8)
Glyoxalase-1 overexpression partially prevents diabetes-induced impaired arteriogenesis in a rat hindlimb ligation model (2016) (8)
Increased Dicarbonyl Stress as a Novel Mechanism of Multi-Organ Failure in Critical Illness (2017) (8)
Effects of tumour necrosis factor-α in the human forearm : blood flow and endothelin-1 release (8)
Association of changes in inflammation with variation in glycaemia, insulin resistance and secretion based on the KORA study (2018) (8)
An integrated set-up for ex vivo characterisation of biaxial murine artery biomechanics under pulsatile conditions (2021) (8)
Low-grade inflammation and endothelial dysfunction predict four-year risk and course of depressive symptoms: The Maastricht study (2021) (8)
Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry (2018) (8)
Effect of a plant sterol-enriched spread on biomarkers of endothelial dysfunction and low-grade inflammation in hypercholesterolaemic subjects (2016) (8)
Metformin use in type 2 diabetic patients is not associated with lower arterial stiffness: the Maastricht Study (2019) (8)
Inflammatory and Angiogenic Factors Linked to Longitudinal Microvascular Changes in Hemodialysis Patients Irrespective of Treatment Dose Intensity (2017) (8)
Mevastatin increases eNO synthase expression and inhibits lipid peroxidation in human endothelial cells. (2007) (8)
Dietary Advanced Glycation End-Products and Colorectal Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study (2021) (8)
Fructose Intake From Fruit Juice and Sugar-Sweetened Beverages Is Associated With Higher Intrahepatic Lipid Content: The Maastricht Study. (2022) (7)
Relationship between de novo lipogenesis and serum sex hormone binding globulin in humans (2021) (7)
Serum Matrix Metalloproteinases and Left Atrial Remodeling—The Hoorn Study (2020) (7)
Habitual Intake of Dietary Advanced Glycation End Products Is Not Associated with Arterial Stiffness of the Aorta and Carotid Artery in Adults: The Maastricht Study (2021) (7)
Altered hepatic sphingolipid metabolism in insulin resistant mice: role of advanced glycation endproducts. (2021) (7)
Response to Comment on: Hanssen et al. Associations Between the Ankle-Brachial Index and Cardiovascular and All-Cause Mortality Are Similar in Individuals Without and With Type 2 Diabetes: Nineteen-Year Follow-Up of a Population-Based Cohort Study. Diabetes Care 2012;35:1731–1735 (2013) (7)
Erythropoietin and vascular endothelial growth factor as risk markers for severe hypoglycaemia in type 1 diabetes. (2010) (7)
C3 and alternative pathway components are associated with an adverse lipoprotein subclass profile: The CODAM study. (2021) (7)
Comment on: Selvin et al. sRAGE and Risk of Diabetes, Cardiovascular Disease, and Death. Diabetes 2013;62:2116–2121 (2013) (7)
The Putative Role of Methylglyoxal in Arterial Stiffening: A Review. (2021) (7)
The Glyoxalase System in Age-Related Diseases: Nutritional Intervention as Anti-Ageing Strategy (2021) (7)
Diet-induced weight loss reduces postprandial dicarbonyl stress in abdominally obese men: Secondary analysis of a randomized controlled trial. (2021) (6)
A 4-Week Diet Low or High in Advanced Glycation Endproducts Has Limited Impact on Gut Microbial Composition in Abdominally Obese Individuals: The deAGEing Trial (2022) (6)
Plasma Methylglyoxal Levels Are Associated With Amputations and Mortality in Severe Limb Ischemia Patients With and Without Diabetes. (2020) (6)
Preparation of advanced glycation end products in vitro. (2007) (6)
Influence of icodextrin on plasma and dialysate levels of N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine. (2005) (6)
Higher Plasma Levels of von Willebrand Factor and C-Reactive Protein During a Peritoneal Dialysis Regimen with Less Glucose and Glucose Degradation Products (2013) (6)
Endothelial Function and Dysfunction (2003) (6)
Dietary Advanced Glycation End Products Consumption as a Direct Modulator of Insulin Sensitivity in Overweight Humans: A Study Protocol for a Double-Blind, Randomized, Two Period Cross-Over Trial (2015) (6)
Kidney and vascular function in adult patients with hereditary fructose intolerance (2020) (5)
Habitual intake of dietary advanced glycation end products is not associated with generalized microvascular function—the Maastricht Study (2021) (5)
The hypoxia-sensor carbonic anhydrase IX affects macrophage metabolism, but is not a suitable biomarker for human cardiovascular disease (2021) (5)
The systolic–diastolic difference in carotid stiffness is increased in type 2 diabetes: The Maastricht Study (2017) (5)
Interleukin-1 beta and transforming growth factor-beta 2 enhance cytosolic high-molecular-mass phospholipase A2 activity and induce prostaglandin E2 formation in rat mesangial cells. (1992) (5)
Soluble Receptor for Advanced Glycation End-products (sRAGE) and Colorectal Cancer Risk: A Case–Control Study Nested within a European Prospective Cohort (2020) (5)
Glucocorticoids affect metabolic but not muscle microvascular insulin sensitivity following high versus low salt intake. (2020) (5)
Cardiac inflammation and microvascular procoagulant changes are decreased in second wave compared to first wave deceased COVID-19 patients (2021) (5)
Comparing inflammatory cell density in the myocardium and coronary arteries in rheumatoid arthritis patients versus controls with myocardial infarction: A post-mortem case-control study. (2016) (5)
Advanced glycation endproducts and dicarbonyls in end-stage renal disease: associations with uraemia and courses following renal replacement therapy (2019) (5)
Blood pressure variability and microvascular dysfunction: the Maastricht Study. (2020) (5)
Interleukin-1 beta-induced cytosolic phospholipase A2 activity and protein synthesis is blocked by dexamethasone in rat mesangial cells. (1993) (4)
Interleukin-1 beta, tumor necrosis factor and forskolin stimulate the synthesis and secretion of group II phospholipase A2 in rat mesangial cells. (1991) (4)
Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression (2019) (4)
THE INFLUENCE OF BICARBONATE/LACTATE-BUFFERED PD FLUIDS ON Nε-(CARBOXYETHYL)LYSINE AND Nε-(CARBOXYMETHYL)LYSINE IN PERITONEAL EFFLUENT (2011) (4)
PS18 - 84. Expression of the complement system is upregulated in subcutaneous adipocytes from non-obese hypertriglyceridemic subjects and is associated with local insulin resistance (2012) (4)
Deletion of RAGE fails to prevent hepatosteatosis in obese mice due to impairment of other AGEs receptors and detoxifying systems (2021) (4)
Plasma concentrations of advanced glycation end-products and colorectal cancer risk in the EPIC study. (2021) (4)
Detection of amyloid-beta and tau in tear fluid of patients with Alzheimer’s disease (2020) (4)
Circulating Polyunsaturated Fatty Acids as Biomarkers for Dietary Intake across Subgroups: The CODAM and Hoorn Studies (2018) (4)
Is skin autofluorescence (SAF) representative of dermal advanced glycation endproducts (AGEs) in dark skin? A pilot study (2020) (4)
Cardiovascular and Patient Phenotype of Extended Haemodialysis: A Critical Analysis of Studying a Unique Patient Population (2018) (4)
Quantification of the B6 vitamers in human plasma and urine in a study with pyridoxamine as an oral supplement; pyridoxamine as an alternative for pyridoxine. (2021) (4)
Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells (2022) (4)
Development and validation of a UPLC-MS/MS method to quantify fructose in serum and urine. (2020) (4)
Blood pressure variability and microvascular dysfunction: The Maastricht Study (2019) (4)
Adipose Tissue Macrophages Induce Hepatic Neutrophil Recruitment And Macrophage Accumulation Without Affecting Atherosclerosis Development In Mice. (2019) (4)
The Increase in Plasma Levels of Nε-(Carboxymethyl)lysine During Icodextrin Treatment of Peritoneal Dialysis Patients Is Not Associated with Increased Plasma Levels of Vascular Cell Adhesion Molecule-1 (2006) (4)
Habitual intake of dietary methylglyoxal is associated with less low-grade inflammation: the Maastricht Study (2022) (3)
Associations of cells from both innate and adaptive immunity with lower nerve conduction velocity: the Maastricht Study (2021) (3)
Liraglutide treatment attenuates inflammation markers in the cardiac, cerebral and renal microvasculature in streptozotocin‐induced diabetic rats (2022) (3)
Genome-wide analysis of constitutional DNA methylation in familial melanoma (2020) (3)
Adipose tissue macrophages do not affect atherosclerosis development in mice. (2019) (3)
Extracerebral microvascular dysfunction is related to brain MRI markers of cerebral small vessel disease: The Maastricht Study (2021) (3)
Purification and characterization of Ca(2+)-dependent phospholipases A2 from rat kidney. (1996) (3)
Associations of dicarbonyl stress with complement activation: the CODAM study (2020) (3)
Lactate Are Increased in Plasma and Urine Samples of Type 2 Diabetes as Measured by a Simultaneous Quantification of L(+) and D(−) Lactate by Reversed-Phase Liquid Chromatography Tandem Mass Spectrometry (2014) (3)
Downregulation of Cytokine-Induced Synthesis and Secretion of Group II Phospholipase A2 (1997) (3)
Physical activity and markers of glycation in older individuals: data from a combined cross-sectional and randomized controlled trial (EXAMIN AGE). (2020) (3)
Association between bone metabolism regulators and arterial stiffness in type 2 diabetes patients. (2018) (3)
Metformin and N-terminal pro B-type natriuretic peptide in type 2 diabetes patients, a post-hoc analysis of a randomized controlled trial (2021) (3)
Carotid stiffness is associated with retinal microvascular dysfunction—The Maastricht study (2019) (3)
Prevention of age‐induced N(ε)‐(carboxymethyl)lysine accumulation in the microvasculature (2016) (3)
Comment on "AGEs mediated expression and secretion of TNF alpha in rat retinal microglia" by Dr Wang et al. (2007) (3)
Is AGE accumulation a therapeutic target for diabetic complications? (2006) (3)
High density lipoproteins exert pro-inflammatory effects on macrophages via passive cholesterol depletion and PKC-NF-kb/stat1-irf1 signaling (2016) (2)
Effects of diet-induced weight loss on postprandial vascular function after consumption of a mixed meal: Results of a randomized controlled trial with abdominally obese men. (2020) (2)
Abstract 2389: Clinical and Prognostic Value of Advanced Glycation End-products (AGEs) in Chronic Heart Failure (2007) (2)
Intrahepatic lipid content is independently associated with soluble E-selectin levels: The Maastricht study. (2022) (2)
Immunometabolism and the modulation of immune responses and host defense: A role for methylglyoxal? (2022) (2)
Effects of diet-induced weight loss on postprandial vascular function after consumption of a mixed meal: results of a randomized controlled trial in abdominally obese men (2018) (2)
Author response: Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis (2016) (2)
Dose-Finding Study of theMultitargeted Tyrosine Kinase Inhibitor SU 6668 in Patients with AdvancedMalignancies (2005) (2)
Advanced glycation endproducts in diabetes-related macrovascular complications: focus on methylglyoxal (2022) (2)
Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity (2017) (2)
Short Duration Alagebrium Chloride Therapy Prediabetes Does Not Inhibit Progression to Autoimmune Diabetes in an Experimental Model (2021) (2)
Endothelial dysfunction and low-grade inflammation are associated with arterial stiffness in healthy adults over a 6-year period (2011) (2)
Clinical and prognostic value of advanced glycation end-products (AGEs) in chronic heart failure (2007) (2)
Comparative studies on plasmalogen biosynthesis in rat brain homogenates and isolated oligodendroglial cells during development (1991) (2)
Myocardial infarction coincides with increased NOX2 and Nε-(carboxymethyl) lysine expression in the cerebral microvasculature (2021) (2)
Effects of dexamethasone and transforming growth factor-β 2 on group II phospholipase A 2 mRNA and activity levels in interleukin 1 β-and forskolin-stimulated mesangial cells (1996) (2)
Serum sex hormone-binding globulin levels are reduced and inversely associated with intrahepatic lipid content and saturated fatty acid fraction in adult patients with glycogen storage disease type 1a (2022) (2)
Greater central-to-peripheral pulse pressure amplification in diabetes and obesity: the relative mediating role of arterial stiffness, heart rate and wave reflection: The CODAM study (2014) (1)
Aldosterone Is Not Associated With Metabolic and Microvascular Insulin Sensitivity in Abdominally Obese Men (2018) (1)
Abstract 1565: Nϵ-(carboxymethyl)lysine Trapping in Adipose Tissue: Implications for Obesity-associated Changes in Adipokine Expression (2009) (1)
Comment on Lee et al. Relation of Change or Substitution of Low- and No-Calorie Sweetened Beverages With Cardiometabolic Outcomes: A Systematic Review and Meta-analysis of Prospective Cohort Studies. Diabetes Care 2022;45:1917-1930. (2023) (1)
IMPACT OF TRANSCRIPTION-FACTOR 7-LIKE (TCF7L2) GENE-VARIANTS ON THE RESPONSE TO ANTI-HYPERGLYCAEMIC TREATMENT IN NON-OBESE PATIENTS WITH TYPE-2 DIABETES (T2DM) (2008) (1)
Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics (2010) (1)
The role of serum and dietary advanced glycation endproducts in relation to cardiac function and structure: The Hoorn Study. (2021) (1)
Skewed X-inactivation is common in the general female population (2018) (1)
Effect of metformin on arginine and dimethylarginines in patients with advanced type 2 diabetes: A post hoc analysis of a randomized trial (2022) (1)
Exercise SBP response and incident depressive symptoms: The Maastricht Study (2020) (1)
Effects of Diet-Induced Weight Loss on Plasma Markers for Cholesterol Absorption and Synthesis: Secondary Analysis of a Randomized Trial in Abdominally Obese Men (2022) (1)
Associations between plasma sRAGE, esRAGE and AGEs in COPD (2013) (1)
Association of variants in upstream transcription factor I (USF1) with type 2 diabetes in the Dutch population (2007) (1)
Effect of increased convective clearance by on-line hemodiafiltration on all-cause cardiovascular mortality in chronic hemodialysis patients (2004) (1)
Effects of fructose restriction on blood pressure: Secondary analysis of a double-blind randomized controlled trial. (2022) (1)
Higher plasma advanced glycation endproducts levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study (2010) (1)
Polymorphisms in Glyoxalase I Gene Are Not Associated with Glyoxalase I Expression in Whole Blood or Markers of Methylglyoxal Stress: The CODAM Study (2021) (1)
LB-PO-865 ASSOCIATION OF VARIANTS IN UPSTREAM TRANSCRIPTION FACTOR 1 (USF1) WITH TYPE 2 DIABETES IN THE DUTCH POPULATION (2007) (1)
Dimorphic Mechanisms of Fragility in Diabetes Mellitus: the Role of Reduced Collagen Fibril Deformation (2022) (1)
Phospholipases A2 and Prostaglandin Formation in Rat Glomerular Mesangial Cells (1994) (1)
Abstract P324: Effects of Sodium and Potassium Supplementation on Endothelial Function and Inflammation in Untreated (Pre)Hypertensives: A Fully Controlled Dietary Intervention Study (2015) (1)
Corrigendum to "Quantification of dicarbonyl compounds in commonly consumed foods and drinks; presentation of a food composition database for dicarbonyls" [Food Chemistry, 339 (2020) 128063]. (2020) (1)
CD11c−MHC2low Macrophages Are a New Inflammatory and Dynamic Subset in Murine Adipose Tissue (2020) (1)
The GLP-1 analogue liraglutide decreases the pro-inflammatory status of the heart in diabetes (2013) (1)
Associations between plasma sulfur amino acids and specific fat depots in two independent cohorts: CODAM and The Maastricht Study (2022) (1)
Regulation of 14 kDa Group II PLA2 in Rat Mesangial Cells (1995) (1)
Erratum to: Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study (2015) (1)
Tu-W19:4 Impact of metformin versus repaglinide on glycemic regulation and non-glycemic cardiovascular risk-markers in non-obese patients with type-2 diabetes (2006) (1)
Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer (2019) (1)
Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3‐deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub‐study (2020) (1)
Plasma advanced glycation end products are not associated with cardiovascular disease in individuals with or without type 2 diabetes: the Hoorn and CODAM studies (2012) (1)
Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference (2020) (1)
Serum sex hormone-binding globulin is a mediator of the association between intrahepatic lipid content and type 2 diabetes: the Maastricht Study (2022) (1)
BclI Glucocorticoid Receptor Polymorphism in Relation to Arterial Stiffening and Cardiac Structure and Function: The Hoorn and CODAM Studies (2017) (1)
5D.06: EFFECTS OF SODIUM AND POTASSIUM SUPPLEMENTATION ON ENDOTHELIAL FUNCTION AND INFLAMMATION IN UNTREATED (PRE)HYPERTENSIVES A FULLY CONTROLLED DIETARY INTERVENTION STUDY (2015) (1)
Expansion of Functional Regulatory T Cells Using Soluble RAGE Prevents Type 1 Diabetes (2020) (1)
PS3 - 18. Advanced glycation endproducts in atherosclerotic plaques: no further increase in patients with diabetes (2011) (0)
[PP.29.05] ALDOSTERONE IS NOT ASSOCIATED WITH INSULIN-MEDIATED MICROVASCULAR RECRUITMENT AND INSULIN SENSITIVITY IN ABDOMINALLY OBESE, BUT OTHERWISE HEALTY MEN (2016) (0)
Advanced glycation endproducts and vascular ageing (2015) (0)
1377 ACTIVATED COMPLEMENT FACTOR 3 IS ASSOCIATED WITH LIVER FAT AND LIVER ENZYMES: THE CODAM STUDY (2012) (0)
SP473THE DEMOGRAPHIC AND CARDIOVASCULAR PHENOTYPE OF EXTENDED AND CONVENTIONAL HAEMODIALYSIS PATIENTS (2017) (0)
A randomized diet‐induced weight‐loss intervention reduces plasma complement C3: Possible implication for endothelial dysfunction (2022) (0)
Pulse pressure partially explains the increased incident cardiovascular disease associated with inflammation in type 1 diabetes: a 12-yr follow-up study (2010) (0)
The Alternative Complement Pathway Is Associated With An Adverse Lipid Profile: The Codam Study (2019) (0)
Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms (2016) (0)
Publisher Correction: Identification of 371 genetic variants for age at first sex and birth linked to externalising behavior (2021) (0)
Chronic low-grade inflammation mediates the association between body mass index and pulse pressure in women with type 1 diabetes: a 20-yr longitudinal study (2008) (0)
The relationship between soluble E-selectin and microvascular complications in type 1 diabetic patients (2001) (0)
Clinical evaluation of a new high-efficiency super flux dialyser in routine bicarbonate hemodialysis: acute phase response, oxidative stress and endothelial dysfunction (2001) (0)
University of Groningen Surface Area of Detachment , Proliferative Vitreoretinopathy , and Pulse Pressure , but not AGEs , are Associated With Retinal (2017) (0)
Re: Adiponectin and renal function: pitfalls of renal function estimates and corrections for BSA (2006) (0)
Higher plasma sRAGE levels are associated with incident cardiovascular morbidity and mortality as well as all-cause mortality in type 1 diabetes: a 12-yr follow-up study (2009) (0)
PS9 - 8. Skin autofluorescence and plasma pentosidine are associated with higher pulse wave velocity in individuals with different glucose metabolism status: preliminary results from the Maastricht Study (2013) (0)
UvA-DARE ( Digital Academic Repository ) Coagulation and inflammation in diabetes mellitus (2007) (0)
Low-grade inflammation and endothelial dysfunction precede the increase in pulse pressure in type 1 diabetes: a 20-yr longitudinal study (2009) (0)
Association of the alternative pathway of complement activation with incident cardiovascular diseases: the CODAM study (2014) (0)
RAGE deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in Western type diet-fed Ldlr−/− mice (2018) (0)
Corrigendum to "The cardiometabolic depression subtype and its association with clinical characteristics: The Maastricht Study" [J. Affect. Disord. 313 (2022) 110-117]. (2023) (0)
Correction for both common and rare cell types in blood is important to identify genes that correlate with age (2021) (0)
Soluble C5b-9, a marker for terminal complement activation, is not associated with markers of atherosclerosis or prevalent cardiovascular disease: The CODAM study (2013) (0)
Type 2 diabetes is associated with altered carotid artery mechanics independently of ageing and mean arterial pressure–The Maastricht study (2014) (0)
Diets poor in fibre, vegetable protein and polyunsaturated fat are associated with inflammation and endothelial dysfunction in type 1 diabetes mellitus: the EURODIAB study (2011) (0)
Specific local cardiovascular changes of Nε-( carboxymethyl ) lysine , VEGF , and Smad 2 in the developing embryos coincide with maternal diabetes induced Congenital Heart Defects (2009) (0)
Advanced Glycation End Products Accumulate in Vascular Smooth Muscle and Modify Vascular but Not Ventricular Properties in Elderly Hypertensive Canines Heart Failure (2008) (0)
Activated complement C3 (C3a) is cross-sectionally associated with carotid intima-media thickness and inversely with the ankle-arm blood pressure index: the CODAM study (2012) (0)
IMPACT OF CHANGES IN SMOKING BEHAVIOUR BETWEEN ADOLESCENCE AND YOUNG ADULTHOOD ON ARTERIAL STIFFNESS IN YOUNG ADULTS. THE NORTHERN IRELAND YOUNG HEARTS PROJECT (2009) (0)
Extracerebral microvascular dysfunction is related to brain MRI markers of cerebral small vessel disease: The Maastricht Study (2021) (0)
increased cytosolic expression of glucokinase in aldo B -/- mouse livers (2020) (0)
The terminal complement complex C5b-9, but not the anaphylatoxin C5a, is cross-sectionally associated with fatty liver disease: the codam study (2015) (0)
PS1 - 6. Pyridoxamine improves adiposity and insulin resistance in high-fed diet induced obese mice (2013) (0)
The effect of atorvastatin therapy on tumour necrosis factor-α and vascular adhesion molecules in patients with type 2 diabetes mellitus with no prior history of coronary heart disease (2011) (0)
An interferon-related signature characterizes the whole blood transcriptome profile of insulin-resistant individuals—the CODAM study (2021) (0)
Increase in the levels of matrix metalloproteinases 3 and 9 is associated with increase in pulse pressure and incident hypertension: 7-year longitudinal study (2013) (0)
High-dose methylprednisolone-induced hepatitis in a patient with multiple sclerosis : A case report and brief review of literature 199 (2013) (0)
Associations of visceral vs. subcutaneous abdominal fat with central vs. peripheral arterial stiffness and the mediating role of low-grade inflammation herein (2014) (0)
PS1 - 2. Plasma levels of Nε-(carboxymethyl)lysine and pentosidine are higher in type 1 diabetes but are not associated with coronary artery calcification (2012) (0)
Alcohol consumption and microvascular dysfunction: a J-shaped association: The Maastricht Study (2023) (0)
Advanced Glycation End Product and Amadori Product Are Increased and Related to Apoptosis in the Human Diabetic Retina. (2004) (0)
Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease (2019) (0)
Higher serum high-mobility group box 1 levels are cross-sectionally associated with micro- and macroalbuminuria, but not with cardiovascular disease in type 1 diabetes: the EURODIAB PCS (2011) (0)
Higher leptin-to-adiponectin ratio is associated with carotid and femoral stiffening in young adults : a 6-yr longitudinal study (2012) (0)
Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation (2018) (0)
517 Skin-autofluorescence, a measure of tissue advanced glycation end-products (AGEs), is related to Diastolic Function in Dialysis Patients (2008) (0)
Modification of Low-Density Lipoprotein by Methylglyoxal Alters its Physico-Chemical and Biological Properties (2005) (0)
Metformin Treatment Is Associated With Increased Serum Levels of Methylmalonic Acid in Patients With Type 2 Diabetes Treated With Insulin: A Placebo-Controlled 4-Year Trial (2013) (0)
The Role Of Low-Grade Inflammation In The Association Between Uric Acid and Atherosclerosis: The Codam Study (2013) (0)
Skin Autofluorescence And Plasma Advanced Glycation End Products Are Increased In Chronic Obstructive Pulmonary Disease (2012) (0)
Abstract 15806: The Glp-1 Analogue Liraglutide Inhibits the Advanced Glycation End-Product Cml and Nox2 in the Diabetic Heart and Brain (2013) (0)
Cytokine Act ivat ion During Attacks of the H yper im m unog lobu l inem ia D and Periodic Fever Syndrome (2017) (0)
T-cell infiltration as determined by CD3 immunohistochemistry. (2013) (0)
Complement factors D and C3 cross-sectionally associate with arterial stiffness, but not independently of metabolic risk factors: The Maastricht Study (2022) (0)
Plasma levels of MMP-2,-3 and-10, and of TIMP-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB prospective complications study (2014) (0)
Abdominal subcutaneous and visceral adipocyte size, lipolysis and inflammation relate to insulin resistance in male obese humans (2018) (0)
3.7 Exercise Systolic Blood Pressure Response And Incident Depressive Symptoms – The Maastricht Study (2020) (0)
704 IS THERE AN ESSENTIAL ROLE FOR ADAPTIVE IMMUNITY UNDERLYING RENIN-ANGIOTENSIN-INDUCED RENAL DAMAGE? (2012) (0)
Activation of the alternative pathway of complement, represented by factor Bb, is longitudinally associated with late beta-cell conservation in type 2 diabetes : The CODAM study (2017) (0)
Liraglutide treatment attenuates dysfunction-related changes in the cardiac and cerebral microvasculature in streptozotocin-induced diabetic rats (2022) (0)
Polymorphisms in glyoxalase 1 gene are not associated with markers of atherosclerosis and arterial stiffness: the Hoorn and CoDAM studies (2008) (0)
Lower heart rate variability, an index of worse autonomic function, is associated with worse beta cell response to a glycemic load in vivo—The Maastricht Study (2023) (0)
PS4 - 22. Endogenous formation of Nε-(Carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis (2011) (0)
Low-grade inflammation mediates the association between the metabolic syndrome and the ankle-arm index (The CODAM study) (2008) (0)
SP291SKIN AUTOFLUORESCENCE LEVELS AND BIOMARKERS OF ENDOTHELIAL DYSFUNCTION AND LOW-GRADE INFLAMMATION ARE HIGHER IN END-STAGE RENAL DISEASE, BUT ARE NOT CONSISTENTLY AFFECTED BY DIALYSIS INITIATION (2018) (0)
University of Groningen Dietary proteins improve endothelial function under fasting conditions but not in the postprandial state, with no effects on markers of low-grade inflammation Teunissen-Beekman, (2015) (0)
(Pre)diabetes, glycemia, and daily glucose variability are associated with retinal nerve fiber layer thickness in The Maastricht Study (2022) (0)
Association of α-Dicarbonyls and Advanced Glycation End Products with Insulin Resistance in Non-Diabetic Young Subjects: A Case-Control Study (2022) (0)
PS1 - 1. Levels of Advanced Glycation Endproducts in carotid atherosclerotic plaques of individuals with and without diabetes correlate with characteristics of rupture-prone lesions (2012) (0)
Plasma advanced glycation end-products predicts outcome in patients with heart failure (2010) (0)
P5.08: NORMALISATION FOR WALL SHEAR STRESS STIMULUS IMPROVES ACCURACY IN THE ASSESSMENT OF GLUCOSE-INDUCED CHANGES IN FLOW-MEDIATED DILATION FOR WALL ACCURACY IN THE ASSESSMENT OF GLUCOSE-INDUCED (0)
Urinary D-lactate levels are increased in type 2 diabetic patients and are inversely associated with ankle arm index: The CODAM study (2010) (0)
patellar tendon in old and young men Mechanical properties and collagen cross-linking of the (2015) (0)
glucose uptake in the Achilles tendon Low-intensity tensile loading increases intratendinous (2015) (0)
patella tendon Region-specific mechanical properties of the human (2013) (0)
Moree fibrosis and thrombotic complications butt similar expression patterns of markers for coagulationn and inflammation in symptomaticc plaques from patients withh type 2 diabetes (2007) (0)
DNA methylation signatures of educational attainment (2018) (0)
Endothelial dysfunction and low-grade inflammation precede the increase in urinary albumin excretion in type 1 diabetes: a 20-yr longitudinal study (2008) (0)
P11.02: BRAIN WHITE MATTER LESIONS AND ARTERIAL WALL PARAMETERS IN MIGRAINE PATIENTS (0)
PS6 - 31. Plasma levels of Nε-(carboxymethyl)lysine are lower in impaired glucose metabolism and type 2 diabetes, and this is partly explained by central obesity: The Hoorn and CODAM studies (2011) (0)
Contribution of group II phospholipase A2 to arachidonic acid release and prostaglandin synthesis by mesangial cells (1994) (0)
A SNP panel for identification of DNA and RNA specimens (2018) (0)
The inverse association between alcohol intake and complement C3 can be attributed to wine consumption and is explained by inflammation, HDL and insulin resistance, the CODAM study (2010) (0)
Habitual intake of dietary dicarbonyls is associated with greater insulin sensitivity and lower prevalence of type 2 diabetes: The Maastricht Study. (2023) (0)
ε ε -(CARBOXYMETHYL)LYSINE AND N ε -(CARBOXYETHYL)LYSINE (2005) (0)
University of Groningen Vitreous advanced glycation endproducts and alpha-dicarbonyls in retinal detachment patients with type 2 diabetes mellitus and non-diabetic controls Fokkens, (2017) (0)
PS7 - 5. Complement factor 3 is longitudinally associated with insulin resistance, glucose tolerance, and incident type 2 diabetes mellitus over a 7-year follow-up period: the CODAM study. (2013) (0)
ISP13: Advanced glycation endproducts in food and medicine (2012) (0)
Poster Session 3 (2012) (0)
PS1 - 2. Role of the tumour suppressor CDKN2A/p16INK4a in the development of perivascular adipose tissue (2013) (0)
First results on the Effects of metformin on endothelial function and inflammatory activity in type 2 diabetes mellitus: the HOME study, a randomized placebo-controlled trial (2004) (0)
PS11 - 2. Higher urinary sodium excretion is weakly associated with albuminuria, but not with retinopathy in type 1 diabetes: the EURODIAB Study (2013) (0)
In the Elderly, Endothelial Dysfunction and Low-grade Inflammation do not Play A Prominent Role in Local Arterial Stiffening – The Hoorn Study - (2010) (0)
Complement Factor 3 Is Associated With Insulin Resistance and With Incident Type 2 Diabetes Mellitus Over a 7-Year Follow-up Period: The CODAM Study (2014) (0)
Circulating and adipose tissue immune cells in tissue‐specific insulin resistance in humans with overweight and obesity (2023) (0)
The cardiometabolic depression subtype and its association with clinical characteristics: The Maastricht Study. (2022) (0)
Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects (2018) (0)
University of Groningen The Course of Skin and Serum Biomarkers of Advanced Glycation Endproducts and Its Association with Oxidative Stress , Inflammation , Disease Severity , and Mortality during ICU Admission in Critically Ill Patients (2017) (0)
ACCUMULATION RATE OF AGEs IN THE SKIN BIOPSY TISSUE OF DIALYSIS PATIENTS (2011) (0)
Genome-wide identification of directed gene networks using large-scale population genomics data (2018) (0)
Cholesterol Levels The ATF6-Met(67)Val Substitution Is Associated With Increased Plasma (2012) (0)
P151 Microvascular Dysfunction is Associated with Impaired Beta-cell Function: The Maastricht Study (2020) (0)
Plasma Advanced Glycation Endproducts and Dicarbonyl Compounds Are Not Associated with Coronary Atherosclerosis in Athletes. (2023) (0)
Plasma levels of N-epsilon-(Carboxymethyl)lysine are inversely associated with BMI and inflammation, and explain a part of the obesity-related increases in inflammation (2013) (0)
Increased Transcription of Connective Tissue Growth Factor in Daibetic Rat Retina: Attenuation With Aminoguanidine (2005) (0)
DELAYED INTERVENTION WITH PYRIDOXAMINE IMPROVES METABOLIC FUNCTION AND PREVENTS ADIPOSE TISSUE INFLAMMATION AND INSULIN RESISTANCE (2016) (0)
YI 2.3 Methylglyoxal, 3-Deoxyglucosone, and Glyoxal – Precursors of Advanced Glycation Endproducts – are not Independently Associated with Indices of Carotid Stiffness: The Maastricht Study (2020) (0)
Abstract 388: High-density Lipoprotein Cholesterol Efflux Capacity is not associated with Atherosclerosis and Cardiovascular Events: the CODAM Study (2018) (0)
THE IMPACT OF MATERNAL DIABETES ON HEART AND VASSCULAR DEVELOPMENT; A POSSIBLE ROLE FOR GLYCATION (2004) (0)
4.P.98 Effect of methylglyoxal on the physico-chemical and biological properties of low density lipoprotein (1997) (0)
PS3 - 17. The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1 (2011) (0)
Association between the metabolic syndrome and coronary artery disease or ankle-arm index: mediation by low-grade inflammation and/or endothelial dysfunction (the CODAM study) (2009) (0)
The hypoxia-sensor carbonic anhydrase IX affects macrophage metabolism, but is not a suitable biomarker for human cardiovascular disease (2021) (0)
disease Phospholipase A 2 levels in acute chest syndrome of sickle cell (2002) (0)
Advanced Glycation Endproduct “AGE” Accumulation in Elderly Hypertensive Canines: Correlation with Effects of AGE Crosslink Breaker (2008) (0)
Glyoxalase-1 Over-expression in Retina Attenuates AGE Formation and Protects Against Diabetes-linked Pathology (2009) (0)
Is the hyperglycemia-induced formation of methylglyoxal the initial inducer of oxidative stress in endothelial cells? (2002) (0)
Plasma concentrations of the methylglyoxal metabolite D-lactate are independently associated with insulin resistance: the CODAM study (2013) (0)
New results in the study of Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized placebo-controlled trial (2004) (0)
PS3 - 14. Glyoxalase-I overexpression partially prevents diabetes-induced impaired arteriogenesis in a rat hind limb ischemia model (2011) (0)
Pyridoxamine prevents increased atherosclerosis by intermittent methylglyoxal spikes in the aortic arches of ApoE-/- mice. (2023) (0)
Complement C3, but not C4, is independently associated with the metabolic syndrome and prevalent cardiovascular disease: the CODAM study (2008) (0)
AGEs induce alterations of sphingolipids metabolism in the liver of genetically- and diet-induced diabetic mice (2018) (0)
Effects of sodium and potassium supplementation on endothelial function (2015) (0)
EP-1088: EGFR as blood biomarker improves prognostic value of nomogram for survival in laryngeal carcinoma (2017) (0)
Genome-wide analysis of constitutional DNA methylation in familial melanoma (2020) (0)
Associations between components of the metabolic syndrome and fatty liver are mediated by insulin resistance and endothelial dysfunction, but not by inflammation (the CODAM study) (2009) (0)
Surface Area of Detachment, Proliferative Vitreoretinopathy, and Pulse Pressure, but not AGEs, are Associated With Retinal Redetachment. (2016) (0)
The Intake of Dicarbonyls and Advanced Glycation Endproducts as Part of the Habitual Diet Is Not Associated with Intestinal Inflammation in Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients (2022) (0)
Circulating TGF-B1 and complications of type 1 diabetes (2000) (0)
Expression of the complement system is upregulated in subcutaneous adipocytes from non-obese hypertriglyceridemic subjects and is associated with local insulin resistance (2012) (0)
PS7 - 4. Complement activation products C5a and sC5b-9 are in a cross-sectional study associated with low-grade inflammation, but not with atherosclerosis: The CODAM study (2013) (0)
Title : Inflammation and premature aging in advanced chronic kidney disease 1 (2017) (0)
Myocardial infarction coincides with increased expression of NO2X2 and the advanced glycation end product N-e-(carboxymethyl) lysine in the microvasculature of the brain (2020) (0)
Higher levels of complement C3a (activated C3) are cross-sectionally associated with higher carotid media thickness and lower ankle-arm blood pressure index: The CODAM study (2012) (0)
Blood lipids influence DNA methylation in circulating cells (2016) (0)
Abstract P307: The Incremental Value of Fourteen Novel Biomarkers for the Prediction of Cardiovascular Risk in Patients with Type 2 Diabetes (2015) (0)
Plasma levels of N epsilon-(carboxymethyl)lysine (CML) are lower in impaired glucose metabolism and type 2 diabetes and this is partly explained by obesity: the Hoorn and CODAM studies (2011) (0)
Association of the alternative pathway of complement activation with inflammation, endothelial dysfunction and carotid intima-media thickness: The codam study (2015) (0)
Normalisation for wall shear stress stimulus improves accuracy in the assessment of glucose-induced changes in flow-mediated dilation (2011) (0)
Serum levels of autoantibodies against the angiotensin II type I receptor are not associated with serum dicarbonyl or AGE levels in patients with an aldosterone-producing adenoma. (2022) (0)
Poster session 3 (2001) (0)
Pyridoxamine reduces methylglyoxal and markers of glycation and endothelial dysfunction, but does not improve insulin sensitivity or vascular function in abdominally obese individuals: A randomized double‐blind placebo‐controlled trial (2023) (0)
Inflammation and Type 2 Diabetes (2017) (0)
Reducing sitting time versus adding exercise: differential effects on biomarkers of endothelial dysfunction and metabolic risk (2018) (0)
Endothelial Dysfunction and Low-grade Inflammation Are Associated With Greater Arterial Stiffness: The Amsterdam Growth and Health Longitudinal Study (AGAHLS) (2009) (0)
P11.06: FIBRONECTIN, BUT NOT LAMININ CONTENT IS INCREASED IN THE TUNICA MEDIA OF SUBCUTANEOUS SMALL RESISTANCE ARTERIES OF PATIENTS WITH ESSENTIAL HYPERTENSION (0)
PS8 - 39. Bcll glucocorticoid receptor polymorphism is associated with greater body fatness and higher insulin resistance: The Hoorn and CODAM Studies (2012) (0)
Associations of the alternative pathway and classical pathway of complement activation with incident metabolic syndrome : The CODAM study (2017) (0)
The association between body fat and circulating complement C3 is largely explained by low-grade inflammation and insulin resistance: the CODAM study (2011) (0)
An interferon-related signature characterizes the whole blood transcriptome profile of insulin-resistant individuals—the CODAM study (2021) (0)
Phospholipases A2 and the Production of Bioactive Lipids (1996) (0)
PS3 - 4. Advanced glycation endproducts are associated with higher ambulatory 24-hour pulse pressure: preliminary results from the Maastricht Study (2013) (0)
Soluble E-Selectin Is A Liver-Derived Endothelial Marker That Is Associated With Nonalcoholic Fatty Liver Disease (2019) (0)
PS1 - 10. Obesity induces CD11c+ macrophages in murine adipose tissue which are distinctive from, but resemble, dendritic cells (2013) (0)
Alternative quantification of flow-mediated dilation provides more specific detection of glucose-induced changes at brachial artery level (2013) (0)
IN-VITRO CHARACTERIZATION OF MOUSE CAROTID ARTERY MECHANICS BY DYNAMIC BIAXIAL PRESSURE-MYOGRAPHY (2019) (0)
cardiac surgery myocardial fibrosis in patients undergoing Calibrated integrated backscatter and and (2017) (0)
Human complement C3 as a risk factor for coronary artetry disease: relation with insulin, but not inflammation (the CODAM study) (2007) (0)
Barcoding in obese: who’s at increased risk for the development of cardiovascular disease? (2019) (0)
PS8 - 36. Higher levels of complement C3a (activated C3) are cross-sectionally associated with higher carotid media thickness and lower ankle-arm blood pressure index: the CODAM Study (2012) (0)
The association between the-374T/A polymorphism of the RAGE gene and blood pressure and arterial stiffness is modified by glucose metabolism status. The Hoorn and CoDAM studies (2009) (0)
Fish consumption is assiociated with improved endothelial function and inflammation scores; prospective results from 'The Amsterdam Growth and Health Longitudinal Study' (2010) (0)
Endothelial dysfunction and inflammation partially explain the association between soluble RAGE and cardiovascular disease and albuminuria in type 1 diabetes: The EURODIAB Study (2008) (0)
Irbesartan treatment does not influence plasma levels of the advanced glycation end products CML and CEL in patients with type 2 diabetes and microalbuminuria. An IRMA2 substudy (2010) (0)
SKIN MICROVASCULAR FLOWMOTION IS UNALTERED IN ABDOMINALLY OBESE MEN (2022) (0)
Genetic deletion of RAGE in Dbdb mice interferes with AGEs receptors and detoxifying systems in liver (2018) (0)
Prevention of dialysis and inflammation induced peritoneal damage by (non-coagulant) heparinoids and suppletion of mesothelial cells (2000) (0)
(Pre)Diabetes, Greater Glycemia, and Greater Daily Glucose Variability are Associated with Lower Retinal Nerve Fiber Layer Thickness, an Index of Neurodegeneration and Precursor of Diabetic Retinopathy– The Maastricht Study (2021) (0)

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