Celia Greenwood
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Canadian biostatistician
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Why Is Celia Greenwood Influential?
(Suggest an Edit or Addition)According to Wikipedia, Celia Margaret Theodora Greenwood is a Canadian biostatistician specializing in statistical genetics. She is a James McGill Professor of Oncology at McGill University. Greenwood was born in Victoria, British Columbia and attended universities in Ontario and Quebec. Greenwood earned a doctorate in biostatistics from the University of Toronto in 1998. She was affiliated with The Hospital for Sick Children and the Dalla Lana School of Public Health before joining the McGill University faculty and the Lady Davis Institute for Medical Research in 2010.
Celia Greenwood's Published Works
Published Works
- The UK10K project identifies rare variants in health and disease (2015) (926)
- Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24 (2007) (757)
- Functional normalization of 450k methylation array data improves replication in large cancer studies (2014) (637)
- Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 (2008) (629)
- Effect of reduced dietary sodium on blood pressure: a meta-analysis of randomized controlled trials. (1996) (594)
- Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals (2012) (459)
- Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture (2015) (399)
- Control genes and variability: absence of ubiquitous reference transcripts in diverse mammalian expression studies. (2002) (373)
- Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study (2015) (355)
- Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis (2017) (323)
- Genetic architecture: the shape of the genetic contribution to human traits and disease (2017) (298)
- Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel (2015) (296)
- Linkage of tuberculosis to chromosome 2q35 loci, including NRAMP1, in a large aboriginal Canadian family. (2000) (220)
- VEGF, FGF1, FGF2 and EGF gene polymorphisms and psoriatic arthritis (2007) (179)
- Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes. (2002) (169)
- Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas (2015) (164)
- The validity of circulating microRNAs in oncology: Five years of challenges and contradictions (2014) (156)
- Data Integration in Genetics and Genomics: Methods and Challenges (2009) (147)
- Germ-line DNA copy number variation frequencies in a large North American population (2007) (146)
- Corrigendum: TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport (2016) (131)
- The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population. (2002) (129)
- Association between the interleukin-1 family gene cluster and psoriatic arthritis. (2006) (128)
- Germline and somatic FGFR1 abnormalities in dysembryoplastic neuroepithelial tumors (2016) (128)
- A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity (2021) (122)
- The Empirical Power of Rare Variant Association Methods: Results from Sanger Sequencing in 1,998 Individuals (2012) (115)
- An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies (2016) (112)
- Phase 2 study of panobinostat with or without rituximab in relapsed diffuse large B-cell lymphoma. (2016) (110)
- A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease (2015) (110)
- Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits (2017) (110)
- On the origin and diffusion of BRCA1 c.5266dupC (5382insC) in European populations (2011) (107)
- A modified score function estimator for multinomial logistic regression in small samples (2002) (104)
- Chromosome 3 Anomalies Investigated by Genome Wide SNP Analysis of Benign, Low Malignant Potential and Low Grade Ovarian Serous Tumours (2011) (98)
- SHLD2/FAM35A co‐operates with REV7 to coordinate DNA double‐strand break repair pathway choice (2018) (95)
- Whole-genome sequence-based analysis of thyroid function (2015) (89)
- Association of LY9 in UK and Canadian SLE families (2008) (88)
- Biopsies: next-generation biospecimens for tailoring therapy (2013) (86)
- Estimating Genome-Wide Significance for Whole-Genome Sequencing Studies (2014) (82)
- Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11 q 23 and replicates risk loci at 8 q 24 and 18 q 21 (2009) (80)
- Measuring and Estimating the Effect Sizes of Copy Number Variants on General Intelligence in Community-Based Samples (2018) (72)
- A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans (2014) (69)
- Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis. (2017) (66)
- Somatic point mutations occurring early in development: a monozygotic twin study (2013) (63)
- The Causal Effect of Vitamin D Binding Protein (DBP) Levels on Calcemic and Cardiometabolic Diseases: A Mendelian Randomization Study (2014) (63)
- Analysis of affected sib pairs, with covariates--with and without constraints. (1999) (62)
- Integrative analysis of multiple gene expression profiles with quality-adjusted effect size models (2005) (61)
- Differential gene profiling in acute lung injury identifies injury-specific gene expression* (2008) (57)
- Adjusted Sequence Kernel Association Test for Rare Variants Controlling for Cryptic and Family Relatedness (2013) (57)
- Association of toll-like receptor 4 variants and ankylosing spondylitis: a case-control study. (2007) (55)
- Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides. (2018) (55)
- The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trial. (2013) (53)
- Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis. (2018) (52)
- Opioid receptor mu 1 gene, fat intake and obesity in adolescence (2014) (52)
- Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status (2013) (51)
- Variants of the SFTPA1 and SFTPA2 genes and susceptibility to tuberculosis in Ethiopia (2006) (50)
- IL-23R Polymorphisms in Patients with Ankylosing Spondylitis in Korea (2009) (50)
- Heritability of neurocognitive traits in familial schizophrenia (2009) (49)
- The Genomic Landscape of TP53 and p53 Annotated High Grade Ovarian Serous Carcinomas from a Defined Founder Population Associated with Patient Outcome (2012) (48)
- Chromosome-breakage genomic instability and chromothripsis in breast cancer (2014) (47)
- The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer (2010) (47)
- Association between Allergies and Risk of Pancreatic Cancer (2014) (45)
- Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity (2017) (43)
- Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity (2008) (43)
- Significant proportion of breast and/or ovarian cancer families of French Canadian descent harbor 1 of 5 BRCA1 and BRCA2 mutations (2004) (42)
- Specific Variants in the MLH1 Gene Region May Drive DNA Methylation, Loss of Protein Expression, and MSI-H Colorectal Cancer (2010) (40)
- Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study (2020) (36)
- Imprinting and deviation from Mendelian transmission ratios. (2001) (36)
- Effect of genome-wide genotyping and reference panels on rare variants imputation. (2012) (36)
- Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time (2018) (35)
- Association of apolipoprotein E polymorphisms and dietary factors in colorectal cancer (2009) (34)
- General psychopathology, internalising and externalising in children and functional outcomes in late adolescence (2019) (34)
- Toward Precision Medicine: TBC1D4 Disruption Is Common Among the Inuit and Leads to Underdiagnosis of Type 2 Diabetes (2016) (32)
- High Systolic Blood Pressure at Hospital Admission Is an Important Risk Factor in Models Predicting Outcome of COVID-19 Patients (2021) (32)
- Association between Variants in Atopy-Related Immunologic Candidate Genes and Pancreatic Cancer Risk (2015) (31)
- Effect Sizes of Deletions and Duplications on Autism Risk Across the Genome. (2020) (31)
- Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis (2019) (31)
- Association between serum total cholesterol level and renal outcome in systemic lupus erythematosus. (2006) (30)
- Interleukin 1 polymorphisms in patients with ankylosing spondylitis in Korea. (2008) (30)
- Incorporation of covariates into genome scanning using sib‐pair analysis in bipolar affective disorder (1997) (29)
- Statistical Issues in a Metaregression Analysis of Randomized Trials: Impact on the Dietary Sodium Intake and Blood Pressure Relationship (1999) (29)
- Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors (2018) (29)
- Maternal Prenatal Mood, Pregnancy-Specific Worries, and Early Child Psychopathology: Findings From the DREAM BIG Consortium. (2020) (28)
- Gene networks show associations with seed region connectivity (2017) (28)
- Statistical Methods for Meta-Analysis of Microarray Data: A Comparative Study (2006) (27)
- Jackknife bias reduction for polychotomous logistic regression. (1997) (27)
- Association of functional variants of PTPN22 and tp53 in psoriatic arthritis: a case-control study (2006) (27)
- Haplotype inference using a Bayesian Hidden Markov model (2007) (25)
- How old is this mutation? - a study of three Ashkenazi Jewish founder mutations (2010) (24)
- Understanding the impact of preprocessing pipelines on neuroimaging cortical surface analyses (2020) (24)
- funtooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types (2015) (24)
- MDiNE: a model to estimate differential co-occurrence networks in microbiome studies (2019) (23)
- Gene Coexpression Analyses Differentiate Networks Associated with Diverse Cancers Harboring TP53 Missense or Null Mutations (2016) (23)
- A hierarchical clustering method for estimating copy number variation. (2007) (23)
- Constitutive Differences in Gene Expression Profiles Parallel Genetic Patterns of Susceptibility to Tuberculosis in Mice (2006) (22)
- Genome-wide analysis of gene dosage in 24,092 individuals estimates that 10,000 genes modulate cognitive ability (2021) (22)
- Association of nuclear factor-kappaB in psoriatic arthritis. (2005) (22)
- Biopsies: next-generation biospecimens for tailoring therapy (2013) (22)
- Low-frequency variation in TP53 has large effects on head circumference and intracranial volume (2018) (22)
- A method for analyzing multiple continuous phenotypes in rare variant association studies allowing for flexible correlations in variant effects (2016) (22)
- Mapping cis-acting regulatory variation in recombinant congenic strains. (2006) (21)
- The HNPCC associated MSH2*1906G→C founder mutation probably originated between 1440 CE and 1715 CE in the Ashkenazi Jewish population (2005) (21)
- Elevated rates of schizophrenia in a familial sample with mental illness and intellectual disability. (2004) (21)
- Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening (2020) (21)
- Down-weighting of multiple affected sib pairs leads to biased likelihood-ratio tests, under the assumption of no linkage. (1999) (21)
- The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene (2016) (21)
- Early or Late Gestational Exposure to Maternal Immune Activation Alters Neurodevelopmental Trajectories in Mice: An Integrated Neuroimaging, Behavioral, and Transcriptional Study (2021) (20)
- Distinguishing differential susceptibility, diathesis-stress, and vantage sensitivity: Beyond the single gene and environment model (2017) (20)
- Optimal selection of markers for validation or replication from genome‐wide association studies (2007) (20)
- Carcinoembryonic Antigen Cell Adhesion Molecule 1 long isoform modulates malignancy of poorly differentiated colon cancer cells (2015) (19)
- Microarray Meta-Analysis Identifies Acute Lung Injury Biomarkers in Donor Lungs That Predict Development of Primary Graft Failure in Recipients (2012) (19)
- Improved prediction of fracture risk leveraging a genome-wide polygenic risk score (2021) (19)
- Multiple Regression Methods Show Great Potential for Rare Variant Association Tests (2012) (19)
- High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis (2011) (19)
- X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells (2018) (19)
- Inheritance patterns of maternal alleles in imprinted regions of the mouse genome at different stages of development (2001) (19)
- PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores (2017) (17)
- Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes (2020) (17)
- Distinct homologous recombination gene expression profiles after neoadjuvant chemotherapy associated with clinical outcome in patients with ovarian cancer. (2018) (16)
- An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies (2015) (16)
- Constrained instruments and their application to Mendelian randomization with pleiotropy (2017) (16)
- The impact of transmission-ratio distortion on allele sharing in affected sibling pairs. (2000) (15)
- An effector index to predict target genes at GWAS loci (2021) (15)
- Correction: Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study (2016) (15)
- A genome-wide linkage study of mammographic density, a risk factor for breast cancer (2011) (15)
- A genome scan for parent-of-origin linkage effects in alcoholism (2005) (15)
- Novel insights into systemic autoimmune rheumatic diseases using shared molecular signatures and an integrative analysis (2017) (14)
- A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination–deficient Pancreatic Cancer (2020) (14)
- Parental Effect of DNA (Cytosine-5) Methyltransferase 1 on Grandparental-Origin-Dependent Transmission Ratio Distortion in Mouse Crosses and Human Families (2008) (13)
- Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer (2021) (13)
- Using the ratio of means as the effect size measure in combining results of microarray experiments (2009) (13)
- WAO International Scientific Conference (WISC 2016) Abstracts (2017) (12)
- Identification of a Radiosensitivity Molecular Signature Induced by Enzalutamide in Hormone-sensitive and Hormone-resistant Prostate Cancer Cells (2019) (12)
- Weighted kernel Fisher discriminant analysis for integrating heterogeneous data (2012) (12)
- A Set-Based Mixed Effect Model for Gene-Environment Interaction and Its Application to Neuroimaging Phenotypes (2017) (12)
- Empirical power of very rare variants for common traits and disease: results from sanger sequencing 1998 individuals (2013) (12)
- Design considerations for association studies of candidate genes in families (2001) (12)
- Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencing (2019) (12)
- Tests for differential gene expression using weights in oligonucleotide microarray experiments (2006) (12)
- Heritability of schizophrenia and major affective disorder as a function of age, in the presence of strong cohort effects (2006) (12)
- Principal component of explained variance: An efficient and optimal data dimension reduction framework for association studies (2016) (10)
- A hidden markov model for identifying differentially methylated sites in bisulfite sequencing data (2018) (10)
- Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis (2019) (10)
- Lack of association of SLC22A4, SLC22A5, SLC9A3R1 and RUNX1 variants in psoriatic arthritis. (2005) (10)
- Analysis of genomic abnormalities in tumors: a review of available methods for Illumina two-color SNP genotyping and evaluation of performance. (2013) (10)
- Machine Learning to Predict Osteoporotic Fracture Risk from Genotypes (2018) (10)
- Combined polygenic risk scores of different psychiatric traits predict general and specific psychopathology in childhood (2020) (10)
- Alternating Optimization for G × E Modelling With Weighted Genetic and Environmental Scores: Examples From the MAVAN Study (2017) (10)
- A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene (2019) (9)
- Pedigree Selection and Tests of Linkage in a Hutterite Asthma Pedigree (2001) (9)
- An Effector Index to Predict Causal Genes at GWAS Loci (2020) (9)
- Bayesian Hyper-LASSO Classification for Feature Selection with Application to Endometrial Cancer RNA-seq Data (2020) (9)
- Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer (2019) (9)
- Regression models for allele sharing: analysis of accumulating data in affected sib pair studies (2002) (9)
- Two-step jackknife bias reduction for logistic regression mles (1994) (9)
- Continuous Covariates in Genetic Association Studies of Case-Parent Triads: Gene and Gene-Environment Interaction Effects, Population Stratification, and Power Analysis (2005) (8)
- Integrative Analysis of Gene Expression Data Including an Assessment of Pathway Enrichment for Predicting Prostate Cancer (2006) (8)
- Joint analysis of multiple blood pressure phenotypes in GAW19 data by using a multivariate rare-variant association test (2016) (8)
- Neuropsychiatric symptoms are early indicators of an upcoming metabolic decline in Alzheimer’s disease (2020) (8)
- Proceedings of the Canadian society of allergy and clinical immunology annual scientific meeting 2015 (2016) (8)
- Exploring the potential benefits of stratified false discovery rates for region-based testing of association with rare genetic variation (2014) (8)
- Early or late gestational exposure to maternal immune activation alters neurodevelopmental trajectories in mice: an integrated neuroimaging, behavioural, and transcriptional study (2020) (8)
- A sequence of methodological changes due to sequencing (2013) (8)
- Genetic Analysis Workshop 19: methods and strategies for analyzing human sequence and gene expression data in extended families and unrelated individuals (2016) (7)
- Evaluation of genetic and environmental effects using GEE and APM methods (1995) (7)
- A rare variant association test in family‐based designs and non‐normal quantitative traits (2016) (7)
- An analytic approach for interpretable predictive models in high‐dimensional data in the presence of interactions with exposures (2018) (7)
- A Polygenic Risk Score to Predict Future Adult Short Stature Among Children (2021) (7)
- A functionally impaired missense variant identified in French Canadian families implicates FANCI as a candidate ovarian cancer-predisposing gene (2021) (6)
- Identifying cis- and trans-acting single-nucleotide polymorphisms controlling lymphocyte gene expression in humans (2007) (6)
- A smoothed EM-algorithm for DNA methylation profiles from sequencing-based methods in cell lines or for a single cell type (2017) (6)
- Prednisone in the treatment of idiopathic membranous nephropathy. (1989) (6)
- Association of Nuclear Factor- κ B in Psoriatic Arthritis (2005) (6)
- A sparse additive model for high-dimensional interactions with an exposure variable (2018) (6)
- Epigenetics and Complex Traits (2013) (6)
- A tree‐based model for allele‐sharing‐based linkage analysis in human complex diseases (2006) (6)
- Integration of “omics” Data and Phenotypic Data Within a Unified Extensible Multimodal Framework (2018) (5)
- The rise to power of the microbiome: power and sample size calculation for microbiome studies (2022) (5)
- Successful treatment of steroid-resistant Weber – Christian disease with biliary ductopenia using cyclosporin (5)
- A Neanderthal OAS1 isoform Protects Against COVID-19 Susceptibility and Severity: Results from Mendelian Randomization and Case-Control Studies (2020) (5)
- Efficiency of reduced logistic regression models (1994) (5)
- Circulating proteins to predict adverse COVID-19 outcomes (2021) (5)
- Dietary Sodium and Blood Pressure-Reply (1996) (5)
- Statistical power in COVID-19 case-control host genomic study design (2020) (5)
- Breast and Ovarian Cancer: The Forgotten Paternal Contribution (2011) (5)
- Detecting cord blood cell type-specific epigenetic associations with gestational diabetes mellitus and early childhood growth (2021) (5)
- Combining Whole-Genome Sequencing and Multimodel Phenotyping To Identify Genetic Predictors of Salmonella Virulence (2020) (5)
- FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice (2018) (5)
- Integrating Affymetrix microarray data sets using probe-level test statistic for predicting prostate cancer (2006) (4)
- Polygenic risk score as a possible tool for identifying familial monogenic causes of complex diseases. (2022) (4)
- Recursive partitioning models for linkage in COGA data (2005) (4)
- Model-Free Linkage Analysis of a Binary Trait. (2017) (4)
- A 10-color flow cytometry panel for diagnosis and minimal residual disease in chronic lymphocytic leukemia (2021) (4)
- The performance of a new local false discovery rate method on tests of association between coronary artery disease (CAD) and genome-wide genetic variants (2017) (4)
- Candidate Markers of Olaparib Response from Genomic Data Analyses of Human Cancer Cell Lines (2021) (4)
- Effects-sizes of deletions and duplications on autism risk across the genome (2020) (4)
- Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models (2018) (4)
- Using Gene Genealogies to Detect Rare Variants Associated with Complex Traits (2014) (4)
- Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases (2023) (3)
- CpG-set association assessment of lipid concentration changes and DNA methylation (2018) (3)
- Outcome-Related Differences in Gene Expression Profiles of High-Grade Serous Ovarian Cancers Following Neoadjuvant Chemotherapy (2019) (3)
- Beta-diversity distance matrices for microbiome sample size and power calculations — How to obtain good estimates (2022) (3)
- A Polygenic Risk Score as a Risk Factor for Medication‐Associated Fractures (2019) (3)
- VEGF , FGF 1 , FGF 2 and EGF gene polymorphisms and psoriatic arthritis (2007) (3)
- Estimating the effect-size of gene dosage on cognitive ability across the coding genome (2020) (3)
- Investigating potential causal relationships between SNPs, DNA methylation and HDL (2018) (3)
- The Genetic and Molecular Analyses of RAD51C and RAD51D Identifies Rare Variants Implicated in Hereditary Ovarian Cancer from a Genetically Unique Population (2022) (3)
- Efficient p-value estimation in massively parallel testing problems (2008) (3)
- Intergenerational Transmission of Well Being–Genetic and Epigenetic Mechanisms (2017) (3)
- EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner (2017) (3)
- Heritable contributions versus genetic architecture (2018) (3)
- New insights into the role of intra-tumor genetic heterogeneity in carcinogenesis: identification of complex single gene variance within tumors (2018) (3)
- Gene genealogies for genetic association mapping, with application to Crohn's disease (2013) (3)
- A flexible copula‐based approach for the analysis of secondary phenotypes in ascertained samples (2019) (2)
- Exome-wide rare variant analyses of two bone mineral density phenotypes: the challenges of analyzing rare genetic variation (2018) (2)
- The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals (2022) (2)
- Evidence of linkage to chromosome 1 for early age of onset of rheumatoid arthritis and HLA marker DRB1 genotype in NARAC data (2007) (2)
- Software Application Profile: RVPedigree: a suite of family-based rare variant association tests for normally and non-normally distributed quantitative traits. (2016) (2)
- A Bayesian nonparametric method for model evaluation: application to genetic studies (2009) (2)
- Multivariate association test for rare variants controlling for cryptic and family relatedness (2019) (2)
- Significance Thresholds for Rare Variant Signals (2015) (2)
- A Tracy-Widom Empirical Estimator For Valid P-values With High-Dimensional Datasets. (2018) (2)
- Sparse Additive Interaction Learning (2018) (2)
- Novel Approaches to Discovery of Biomarkers in Rheumatoid Arthritis: Comment on the Article by Oswald et al (2015) (2)
- Corrections to the parameterization of constraints on allele sharing in sibling pairs alter covariate-parameter estimates but not sharing-probability estimates or power of tests for linkage. (2005) (2)
- Identifying Causes of Fracture Beyond Bone Mineral Density: Evidence From Human Genetics (2022) (2)
- Model-free linkage analysis of a binary trait. (2012) (2)
- RE: Familial aggregation of clinical and neurocognitive features in sibling pairs with and without schizophrenia (2010) (2)
- Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity (2017) (2)
- The genetic analysis of a founder Northern American population of European descent identifies FANCI as a candidate familial ovarian cancer risk gene (2020) (2)
- Germline Missense Variants in CDC20 Result in Aberrant Mitotic Progression and Familial Cancer (2021) (2)
- On Statistical Power for Case-Control Host Genomic Studies of COVID-19 (2020) (2)
- Block coordinate descent algorithm improves variable selection and estimation in error‐in‐variables regression (2021) (2)
- Breast and ovarian cancer: Y do we forget about dad? (2010) (2)
- Models for variable and age-dependent penetrances in genetic linkage analysis (1998) (2)
- Corrigendum: Exploring the potential benefits of stratified false discovery rates for region-based testing of association with rare genetic variation (2014) (2)
- Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer (2021) (2)
- Pathway analysis for genetic association studies: to do, or not to do? That is the question (2014) (2)
- Asymmetric influence measure for high dimensional regression (2020) (2)
- Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis (2019) (2)
- A novel statistical method for modeling covariate effects in bisulfite sequencing derived measures of DNA methylation (2020) (2)
- Microbial community modelling and diversity estimation using the hierarchical Pitman-Yor process (2020) (1)
- Salt, blood pressure, and cointervention. (1997) (1)
- Detecting differentially methylated regions in bisulfite sequencing data using quasi-binomial mixed models with smooth covariate effect estimates (2021) (1)
- Abstract 1977: The protein phosphatase 2 subunit PR48 is a novel melanoma tumor suppressor gene. (2013) (1)
- Measuring and Estimating the Effect Size of Rare Non-Recurrent Deletions and Duplications on General Intelligence (2020) (1)
- Improved prediction of fracture risk leveraging a genome-wide polygenic risk score (2021) (1)
- The General Impact of Haploinsufficiency on Brain Connectivity Underlies the Pleiotropic Effect of Neuropsychiatric CNVS (2020) (1)
- Identifying Differential Methylation in Cancer Epigenetics via a Bayesian Functional Regression Model (2021) (1)
- START: Susceptibility to Food Allergies in a Registry of Twins (2016) (1)
- Response to: Correcting for cell-type effects in DNA methylation studies: reference-based method outperforms latent variable approaches in empirical studies (2017) (1)
- Author response: Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer (2021) (1)
- Correction: Multiple Regression Methods Show Great Potential for Rare Variant Association Tests (2013) (1)
- Single base-pair resolution analysis of DNA binding motif with MoMotif reveals an oncogenic function of CTCF zinc-finger 1 mutation (2022) (1)
- ARRm : Adaptive Robust Regression method for normalization of methylation data (2013) (1)
- KSPM: A Package For Kernel Semi-Parametric Models (2020) (1)
- Low-frequency variation in TP53 has large effects on head circumference and intracranial volume (2019) (1)
- Thousands of CpGs Show DNA Methylation Differences in ACPA-Positive Individuals (2021) (1)
- Estimating the effects of copy‐number variants on intelligence using hierarchical Bayesian models (2020) (1)
- Translational and HIF1α-dependent metabolic reprograming underpin oncometabolome plasticity and synergy between oncogenic kinase inhibitors and biguanides (2017) (1)
- A 10-Color Flow Cytometry Panel for Both Diagnosis and Minimal Residual Disease Measurement in Chronic Lymphocytic Leukemia (2019) (1)
- Microbial community modelling and diversity estimation using the hierarchical Pitman-Yor process (2020) (1)
- Identity-by-descent sharing using Markov chain Monte Carlo in subsets of the asthma Hutterite pedigree (2001) (1)
- Statistical power in COVID-19 case-control host genomic study design (2020) (1)
- Analysis 4: Genetic analysis of the role of the HLA region in inflammatory bowel disease (2002) (1)
- Erratum: Whole-genome sequence-based analysis of thyroid function (2015) (1)
- Statistical power in COVID-19 case-control host genomic study design (2020) (1)
- Genome wide analysis of gene dosage in 24,092 individuals shows that 10,000 genes modulate cognitive ability (2020) (1)
- 6 DIFFERENTIAL EFFECTS OF DELETIONS AND DUPLICATIONS ON AUTISM RISK ACROSS THE GENOME (2019) (1)
- Assessing transmission ratio distortion in extended families: a comparison of analysis methods (2016) (1)
- Linkage and association analysis in pedigrees from different populations (2005) (1)
- More on Dietary Sodium and Blood Pressure-Reply (1997) (1)
- Low Frequency Coding Variation in CYP2R1 has Large Effects on Vitamin D Level and Risk of Multiple Sclerosis (2017) (1)
- Genetic determinants of polygenic prediction accuracy within a population (2022) (1)
- Abstract B24: Using a unique genetically modified ovarian cancer cell line model to identify the targets for siRNA directed therapies (2013) (0)
- Exome-wide rare variant analyses of two bone mineral density phenotypes: the challenges of analyzing rare genetic variation (2018) (0)
- Universitet Low-frequency variation in TP 53 has large effects on head circumference and intracranial (2019) (0)
- Chromosomal Clustering of Periodically Expressed Genes in Plasmodium falciparum (2007) (0)
- An analytic approach for interpretable predictive models in high dimensional data, in the presence of interactions with exposures (2017) (0)
- A novel immune cell signature predicts pathological complete response to neoadjuvant chemotherapy in triple negative breast cancer patients in the Q-CROC3 trial. (2022) (0)
- Cumulative impact of 10 common genetic variants on colorectal cancer risk in 42,333 individuals from eight populations (2013) (0)
- Meta-analysis is Consistent With Dopaminergic Perceptual and Cognitive Prediction Errors (2020) (0)
- 40 MAPPING THE EFFECT-SIZE OF GENE DOSAGE ON GENERAL INTELLIGENCE ACROSS THE GENOME (2019) (0)
- F72MEASURING AND ESTIMATING THE EFFECT SIZE OF RARE NON-RECURRENT DELETIONS AND DUPLICATIONS ON GENERAL INTELLIGENCE (2019) (0)
- Correction: The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals (2022) (0)
- Methods for Family-Based Rare-Variant Genetic Association Tests (2016) (0)
- GD2 and GD3 gangliosides as diagnostic biomarkers for all stages and subtypes of epithelial ovarian cancer (2023) (0)
- Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencing (2019) (0)
- A phase IV study using multi-omics to identify mechanisms of response and resistance to crizotinib in ALK+ advanced non-small cell lung cancer (NSCLC) patients with distinct progression free survival outcomes. (2017) (0)
- Biopsies: next-generation biospecimens for tailoring therapy (vol 10, pg 437, 2013) (2013) (0)
- Value of homogenous populations for gene identification in complex rheumatic diseases. (2005) (0)
- Mixture of Extended Linear Mixed-Effects Models for Clustering of Longitudinal Data (2014) (0)
- A General Framework for Variable Selection in Linear Mixed Models with Applications to Genetic Studies with Structured Populations (2018) (0)
- Bayesian Hyper-LASSO Classification for Feature Selection with Application to Endometrial Cancer RNA-seq Data (2020) (0)
- Whole-genome sequencing and deep imputation identifies non-coding variants near Engrailed-1 with large effects on bone mineral density and fracture (2015) (0)
- Molecular Genetic Characteristics of FANCI, a Proposed New Ovarian Cancer Predisposing Gene (2023) (0)
- Circulating proteins to predict COVID-19 severity. (2023) (0)
- At the interface (2020) (0)
- Abstract 5528: The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene (2017) (0)
- Abstract 117: Genetic landscapes of relapsed and refractory diffuse large B cell lymphomas (2016) (0)
- Capturing additional genetic risk from family history for improved polygenic risk prediction (2022) (0)
- Variable Selection in Linear Mixed Models for SNP Data [R package ggmix version 0.0.1] (2020) (0)
- (2017). Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis. Nature Genetics , , 1468–1475. (2017) (0)
- Detecting cord blood cell type-specific epigenetic associations with gestational diabetes mellitus and early childhood growth (2021) (0)
- Abstract 3888: Molecular profiling of sequential biopsies in patients with metastatic colorectal cancer identifies genomic alterations that evolve during first-line therapy and could have therapeutic implications: A prospective study to identify molecular mechanisms of clinical resistance (QCROC-01: (2015) (0)
- A Randomized, Phase II Study with Biomarker Analysis of Panobinostat with or without Rituximab in Relapsed Diffuse Large B Cell Lymphoma (2015) (0)
- (2017). Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis. (2), 227-238. (2017) (0)
- DRAFT ONLY. NOT FOR CIRCULATION 2006-753-1 Association of Toll-like Receptor 4 Variants and Ankylosing Spondylitis: A Case-Control Study (2007) (0)
- Identification of a Radiosensitivity Molecular Signature Induced by Enzalutamide in Hormone-sensitive and Hormone-resistant Prostate Cancer Cells (2019) (0)
- Sparse Additive Interaction Learning [R package sail version 0.1.0] (2019) (0)
- Whole-genome sequence-based analysis of thyroid function (vol 6, 5681, 2015) (2015) (0)
- An algorithm-based multiple detection influence measure for high dimensional regression using expectile (2021) (0)
- Genetic analyses of DNA repair pathway associated genes implicate new candidate cancer predisposing genes in ancestrally defined ovarian cancer cases (2023) (0)
- P145 INACTIVATION OF IRF1 CAUSES SUSCEPTIBILITY TO COLITIS-ASSOCIATED COLORECTAL CANCER (2019) (0)
- Genetic and Epigenetic Variation at the H19 Imprinted Region and Its Effect on Birth Weight (2017) (0)
- Abstract LB-019: FGFR1 abnormalities in seizure-associated familial and sporadic dysembryoplastic neuroepithelial tumors (2016) (0)
- Suicidal ideation is common in autosomal dominant Alzheimer's disease at‐risk persons (2020) (0)
- Normalizing Illumina Infinium Human Methylation 450 k for multiple cell types with funtooNorm (2017) (0)
- Simulated data for testing cell type adjustment methods (2015) (0)
- Whole-genome sequencing identifies non-coding variants near EN 1 with large effects on bone mineral density (2014) (0)
- Microbial diversity estimation and hill number calculation using the hierarchical Pitman-Yor process (2022) (0)
- Genomic Prediction of Osteoporosis Using 426,000 Individuals from UK Biobank (2018) (0)
- A functionally impaired missense variant identified in French Canadian families implicates FANCI as a candidate ovarian cancer-predisposing gene (2021) (0)
- Statistical Modeling of GxE (2021) (0)
- Common functional polymorphisms in toll-like receptor 4 (TLR4) are not associated with asthma or atopy-related phenotypes. (2002) (0)
- 251. Measuring and Estimating the Effects of Rare Variants, Genome-Wide, on Cognition (2019) (0)
- Cross-Species, Cross-Platform, Meta-Analysis of Acute Lung Injury (ALI) and Ventilator Induced Lung Injury (VILI) Microarrays. (2009) (0)
- Chromosome-breakage genomic instability and chromothripsis in breast cancer (2014) (0)
- SA47 QUANTIFYING THE EFFECT OF COPY-NUMBER VARIANTS ON GENERAL INTELLIGENCE IN UNSELECTED POPULATIONS (2019) (0)
- Transmission Ratio Distortion in Extended Families (2015) (0)
- Abstract POSTER-TECH-1101: Characterization of genomic landscapes of BRCA1 and BRCA2 implicated ovarian cancer specimens from a founder french canadian population (2015) (0)
- X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells (2018) (0)
- Integrating DNA Methylation and Gene Expression data in Placenta Tissue to Predict Childhood Obesity (2015) (0)
- Genetic predisposition to depression and inflammation impacts symptom burden and survival in patients with head and neck cancer: A longitudinal study. (2023) (0)
- Neuropsychiatric symptoms are early indicators of an upcoming metabolic decline in Alzheimer’s disease (2021) (0)
- Considering strategies for SNP selection in genetic and polygenic risk scores (2022) (0)
- SUICIDAL IDEATION IS PREVALENT IN BOTH ASYMPTOMATIC AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE MUTATION AND NON-MUTATION CARRIERS (2018) (0)
- Statistical Genetic Modeling and Analysis of Complex Traits (2014) (0)
- MORE ON DIETARY SODIUM AND BLOOD PRESSURE. AUTHORS' REPLY (1997) (0)
- Dementia with Lewy bodies post-mortem brains reveal differentially methylated CpG sites with biomarker potential (2022) (0)
- Neuropsychiatric symptoms herald metabolic decline in Alzheimer’s disease (2020) (0)
- Genetic and environmental factors predict multivariate trajectories of maternal distress after birth (2021) (0)
- Abstract 2056: The genomic landscape of carriers of rare variants in FANCI, a new candidate ovarian cancer predisposing gene (2021) (0)
- The 2020 Annual Meeting of the International Genetic Epidemiology Society. (2020) (0)
- Circulating Proteins Influencing Psychiatric Disease: A Mendelian Randomization Study (2022) (0)
- Validation of linkage by sampling based on environmental exposures (1999) (0)
- A Bayesian hierarchical model for improving measurement of 5mC and 5hmC levels: Toward revealing associations between phenotypes and methylation states (2022) (0)
- Asthma, Gender and the Epigenetic Clock (2020) (0)
- Response to: Correcting for cell-type effects in DNA methylation studies: reference-based method outperforms latent variable approaches in empirical studies (2017) (0)
- LIST AND AFFILIATIONS (2017) (0)
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