Charles Auffray
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Biology
Charles Auffray's Degrees
- PhD Biomedical Engineering Université Paris Cité
- Bachelors Biology University of Oxford
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(Suggest an Edit or Addition)Charles Auffray's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. (2005) (2214)
- The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression. (1996) (1211)
- F1000Prime recommendation of An index to quantify an individual's scientific research output. (2005) (1129)
- A Gene Map of the Human Genome (1996) (1080)
- A physical map of 30,000 human genes. (1998) (670)
- DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis. (2016) (627)
- The chicken B locus is a minimal essential major histocompatibility complex (1999) (614)
- The class II molecules of the human and murine major histocompatibility complex (1984) (614)
- Towards standardization of RNA quality assessment using user-independent classifiers of microcapillary electrophoresis traces (2005) (540)
- A radiation hybrid map of the human genome. (1996) (467)
- Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort (2015) (400)
- Systems medicine: the future of medical genomics and healthcare (2009) (375)
- Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004) (346)
- Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens (1992) (331)
- A molecular map of the chicken major histocompatibility complex: the class II beta genes are closely linked to the class I genes and the nucleolar organizer. (1988) (263)
- T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED (2017) (246)
- Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia. (2005) (245)
- Application of ’omics technologies to biomarker discovery in inflammatory lung diseases (2013) (236)
- Systems medicine and integrated care to combat chronic noncommunicable diseases (2011) (230)
- Revolutionizing medicine in the 21st century through systems approaches. (2012) (227)
- Isotypic and allotypic variation of human class II histocompatibility antigen α-chain genes (1984) (212)
- U‐BIOPRED clinical adult asthma clusters linked to a subset of sputum omics (2017) (210)
- Making sense of big data in health research: Towards an EU action plan (2016) (205)
- Novel gene transcripts preferentially expressed in human muscles revealed by quantitative hybridization of a high density cDNA array. (1996) (189)
- The P4 Health Spectrum – A Predictive, Preventive, Personalized and Participatory Continuum for Promoting Healthspan (2017) (170)
- MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine (2011) (166)
- Dopaminergic neurons of the substantia nigra modulate preproenkephalin A gene expression in rat striatal neurons (1988) (162)
- Two Mhc class I and two Mhc class II genes map to the chicken Rfp-Y system outside the B complex. (1994) (160)
- Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure (2016) (156)
- An integrative systems biology approach to understanding pulmonary diseases. (2010) (154)
- DNA methylation in childhood asthma: an epigenome-wide meta-analysis. (2018) (153)
- Predictive, preventive, personalized and participatory medicine: back to the future (2010) (153)
- Assignment of Rfp-Y to the chicken major histocompatibility complex/NOR microchromosome and evidence for high-frequency recombination associated with the nucleolar organizer region. (1996) (150)
- A Transcriptome‐driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U‐BIOPRED (2017) (149)
- Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes (2017) (147)
- Sputum transcriptomics reveal upregulation of IL‐1 receptor family members in patients with severe asthma (2017) (135)
- A Severe Asthma Disease Signature from Gene Expression Profiling of Peripheral Blood from U‐BIOPRED Cohorts (2017) (135)
- Participatory medicine: a driving force for revolutionizing healthcare (2013) (134)
- cDNA clone for the heavy chain of the human B cell alloantigen DC1: strong sequence homology to the HLA-DR heavy chain. (1982) (131)
- HNF1α Inactivation Promotes Lipogenesis in Human Hepatocellular Adenoma Independently of SREBP-1 and Carbohydrate-response Element-binding Protein (ChREBP) Activation* (2007) (131)
- Deciphering cellular states of innate tumor drug responses (2006) (130)
- Gene organization of DC and DX subregions of the human major histocompatibility complex. (1985) (129)
- A program for prediction of protein secondary structure from nucleotide sequence data: application to histocompatibility antigens (1984) (122)
- From functional genomics to systems biology: concepts and practices. (2003) (121)
- Physical linkage of a guanine nucleotide-binding protein-related gene to the chicken major histocompatibility complex. (1989) (118)
- A polymorphic system related to but genetically independent of the chicken major histocompatibility complex (2004) (115)
- Chicken major histocompatibility complex class II B genes: analysis of interallelic and inter‐locus sequence variance (1993) (109)
- COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (107)
- Characterization of avian natural killer cells and their intracellular CD3 protein complex (1994) (107)
- Isolation of chicken major histocompatibility complex class II (B‐L) beta chain sequences: comparison with mammalian beta chains and expression in lymphoid organs. (1988) (106)
- Concerted evolution of two Mhc class II B loci in pheasants and domestic chickens. (1999) (103)
- “T2-high” in severe asthma related to blood eosinophil, exhaled nitric oxide and serum periostin (2019) (95)
- The Genexpress Index: a resource for gene discovery and the genic map of the human genome. (1995) (94)
- Severe Chronic Allergic (and Related) Diseases: A Uniform Approach – A MeDALL – GA2LEN – ARIA Position Paper (2012) (93)
- Are allergic multimorbidities and IgE polysensitization associated with the persistence or re‐occurrence of foetal type 2 signalling? The MeDALL hypothesis (2015) (93)
- Genome‐Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow‐up (2017) (91)
- Pathway discovery using transcriptomic profiles in adult‐onset severe asthma (2017) (91)
- The beta-catenin pathway is activated in focal nodular hyperplasia but not in cirrhotic FNH-like nodules. (2008) (91)
- The road from systems biology to systems medicine (2013) (91)
- Enabling multiscale modeling in systems medicine (2014) (90)
- Coordination of intrinsic, extrinsic, and endoplasmic reticulum-mediated apoptosis by imatinib mesylate combined with arsenic trioxide in chronic myeloid leukemia. (2005) (90)
- Genetic mapping of a human class II antigen beta-chain cDNA clone to the SB region of the HLA complex. (1983) (89)
- At Least One Class I Gene in Restriction Fragment Pattern-Y (Rfp-Y), the Second MHC Gene Cluster in the Chicken, Is Transcribed, Polymorphic, and Shows Divergent Specialization in Antigen Binding Region1 2 (2001) (88)
- The amino acid sequence and gene organization of the heavy chain of the HLA-DR antigen: homology to immunoglobulins. (1982) (87)
- Drug specific resistance to oxaliplatin is associated with apoptosis defect in a cellular model of colon carcinoma (2002) (83)
- Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar. (2012) (82)
- Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story (2016) (80)
- Scale relativity theory and integrative systems biology: 1. Founding principles and scale laws. (2008) (79)
- Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis (2019) (79)
- The major histocompatibility complex in the chicken. (1989) (79)
- Molecular genetics of the human major histocompatibility complex. (1986) (79)
- Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms (2018) (78)
- Representing and querying disease networks using graph databases (2016) (78)
- 'The 39 steps' in gene expression profiling: critical issues and proposed best practices for microarray experiments. (2005) (74)
- Personalized respiratory medicine: exploring the horizon, addressing the issues. Summary of a BRN-AJRCCM workshop held in Barcelona on June 12, 2014. (2015) (74)
- Primary structure and ontogeny of an avian CD3 transcript. (1991) (72)
- Sequence of rat intestinal vitamin D-dependent calcium-binding protein derived from a cDNA clone. Evolutionary implications. (1983) (71)
- The Genexpress IMAGE knowledge base of the human brain transcriptome: a prototype integrated resource for functional and computational genomics. (1999) (68)
- Mitochondria-cytoskeleton interaction: distribution of β-tubulins in cardiomyocytes and HL-1 cells. (2011) (68)
- SB subregion of the human major histocompatibility complex: gene organization, allelic polymorphism and expression in transformed cells. (1985) (67)
- Specific gene expression signature associated with development of autoimmune type-I diabetes using whole-blood microarray analysis (2010) (66)
- The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts* (2007) (66)
- Bridging the gap between systems biology and medicine (2009) (66)
- A minimum of four human class II α-chain genes are encoded in the HLA region of chromosome 6 (1983) (65)
- Systems medicine approaches for the definition of complex phenotypes in chronic diseases and ageing. From concept to implementation and policies. (2014) (64)
- Organization of a functional chicken class II B gene (2004) (64)
- Identification and prospective stability of electronic nose (eNose)–derived inflammatory phenotypes in patients with severe asthma (2019) (64)
- Isolation and characterization of three class II MHC genomic clones from the chicken. (1989) (63)
- Mapping of the genetically independent chicken major histocompatibility complexes B@ and RFP-Y@ to the same microchromosome by two-color fluorescent in situ hybridization. (1996) (62)
- IL-17-high asthma with features of a psoriasis immunophenotype. (2019) (62)
- Mouse immunoglobulin genes: a bacterial plasmid containing the entire coding sequence for a pre-gamma 2a heavy chain. (1980) (60)
- Identification of altered gene expression in skeletal muscles from Duchenne muscular dystrophy patients (2001) (58)
- Structure, biosynthesis, and polymorphism of chicken MHC class II (B-L) antigens and associated molecules. (1986) (57)
- Mouse heavy chain variable regions: nucleotide sequence of a germ-line VH gene segment. (1981) (57)
- Finding new genes faster than ever (1993) (57)
- The rat vitamin-D-dependent calcium-binding protein (9-kDa CaBP) gene. Complete nucleotide sequence and structural organization. (1988) (57)
- Scale relativity theory and integrative systems biology: 2. Macroscopic quantum-type mechanics. (2008) (57)
- Exposure to Traffic-Related Air Pollution and Serum Inflammatory Cytokines in Children (2016) (56)
- Polymorphism and complexity of the human DC and murine I‐A alpha chain genes. (1983) (55)
- Molecular Genetics of the Chicken MHC: Current Status and Evolutionary Aspects (1990) (54)
- Biochemical and transcriptomic analyses of two bovine skeletal muscles in Charolais bulls divergently selected for muscle growth. (2005) (53)
- Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis (2018) (52)
- The genexpress IMAGE knowledge base of the human muscle transcriptome: a resource of structural, functional, and positional candidate genes for muscle physiology and pathologies. (1999) (52)
- Community-driven roadmap for integrated disease maps (2018) (51)
- HLA DR, DQ, and DP antigen expression in rheumatoid synovial cells: a biochemical and quantitative study. (1987) (51)
- Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens (1988) (50)
- Regulation of T helper‐B lymphocyte adhesion through CD4‐HLA class II interaction (1990) (48)
- Identification of a cDNA clone coding for the acetylcholine binding subunit of Torpedo marmorata acetylcholine receptor. (1982) (47)
- Airway microbiota signals anabolic and catabolic remodeling in the transplanted lung (2017) (47)
- Computational disease modeling – fact or fiction? (2009) (47)
- Identification of 16 Chicken Microchromosomes by Molecular Markers Using Two-colour Fluorescence In Situ Hybridization (FISH) (1998) (46)
- Transcriptome analysis of two bovine muscles during ontogenesis. (2003) (46)
- Speculations on sequence homologies between the fibronectin cell-attachment site, major histocompatibility antigens, and a putative AIDS virus polypeptide. (1986) (46)
- Gene expression profiling of human satellite cells during muscular aging using cDNA arrays. (2003) (45)
- Stratification of asthma phenotypes by airway proteomic signatures. (2019) (44)
- DNA sequences (1992) (44)
- Report on EU–USA Workshop: How Systems Biology Can Advance Cancer Research (27 October 2008) (2009) (43)
- HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4. (1994) (42)
- Protein subnetwork markers improve prediction of cancer outcome (2007) (41)
- Complementary DNA Arrays Identify CD63 Tetraspanin and α3 Integrin Chain as Differentially Expressed in Low and High Metastatic Human Colon Carcinoma Cells (2002) (41)
- Structure of the constant and 3' untranslated regions of the murine Balb/c gamma 2a heavy chain messenger RNA. (1980) (41)
- Severe asthma exists despite suppressed tissue inflammation: findings of the U-BIOPRED study (2016) (40)
- Self–organized living systems: conjunction of a stable organization with chaotic fluctuations in biological space–time (2003) (39)
- A primary expression map of the chromosome 15q15 region containing the recessive form of limb-girdle muscular dystrophy (LGMD2A) gene. (1995) (38)
- Systems biologists seek fuller integration of systems biology approaches in new cancer research programs. (2010) (37)
- Synthetic CD4 exocyclic peptides antagonize CD4 holoreceptor binding and T cell activation (1996) (37)
- Traditional Knowledge-based Medicine: A Review of History, Principles, and Relevance in the Present Context of P4 Systems Medicine (2017) (36)
- The cytoskeleton-associated PDZ-LIM protein, ALP, acts on serum response factor activity to regulate muscle differentiation. (2007) (36)
- A systems medicine clinical platform for understanding and managing non- communicable diseases. (2014) (36)
- Identification of the Tapasin gene in the chicken major histocompatibility complex (1999) (36)
- P4 medicine needs P4 education. (2014) (35)
- Molecular cloning of the avian β‐nerve growth factor gene: transcription in brain (1986) (35)
- Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma (2017) (35)
- Editorial: Systems biology and personalized medicine – the future is now (2012) (35)
- ALP and MLP distribution during myofibrillogenesis in cultured cardiomyocytes. (2003) (34)
- Isotypic and allotypic variation of human class II histocompatibility antigen alpha-chain genes. (1984) (34)
- From genomic medicine to precision medicine: highlights of 2015 (2016) (33)
- Sequence of a Complete Chicken BG Haplotype Shows Dynamic Expansion and Contraction of Two Gene Lineages with Particular Expression Patterns (2014) (33)
- A Functional and Regulatory Network Associated with PIP Expression in Human Breast Cancer (2009) (33)
- Longitudinally Stable, Clinically Defined Clusters of Patients with Asthma Independently Identified in the ADEPT and U-BIOPRED Asthma Studies. (2016) (32)
- Contribution of airway eosinophils in airway wall remodeling in asthma: Role of MMP‐10 and MET (2019) (32)
- Systems Medicine: The Future of Medical Genomics, Healthcare, and Wellness. (2016) (32)
- Structure and expression of HLA-DQα and -DXα genes: interallelic alternate splicing of the HLA-DQα gene and functional splicing of the HLA-DXα gene using a retroviral vector (2004) (32)
- Host Transcription Profile in Nasal Epithelium and Whole Blood of Hospitalized Children Under 2 Years of Age With Respiratory Syncytial Virus Infection (2017) (31)
- Mouse immunoglobulin A: nucleotide sequence of the structural gene for the alpha heavy chain derived from cloned cDNAs. (1981) (30)
- Characterization of a new human isoform of the enigma homolog family specifically expressed in skeletal muscle. (2004) (30)
- Origins of Systems Biology in William Harvey’s Masterpiece on the Movement of the Heart and the Blood in Animals (2009) (30)
- Comparison of mouse immunoglobulin gamma 2a and gamma 2b chain genes suggests that exons can be exchanged between genes in a multigenic family. (1981) (30)
- Attempt to detect recombination between B-F and B-L genes within the chicken B complex by serological typing, in vitro MLR, and RFLP analyses (2004) (29)
- Towards a European health research and innovation cloud (HRIC) (2020) (29)
- Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays (2002) (27)
- Bridging Systems Medicine and Patient Needs (2015) (27)
- Correlation between D region structure and antigen-binding specificity: evidences from the comparison of closely related immunoglobulin VH sequences. (1981) (26)
- Transforming Growth Factor-β1—Modulated Cerebral Gene Expression (2002) (26)
- Exclusion of muscle specific actinin-associated LIM protein (ALP) gene from 4q35 facioscapulohumeral muscular dystrophy (FSHD) candidate genes (1999) (26)
- Regional assignment of 64 human gene transcripts on chromosome 8. (1997) (26)
- Molecular characterization of three Mhc class II B haplotypes in the ring-necked pheasant (2004) (25)
- Structure and expression of a chicken MHC class I gene (2005) (25)
- Rapid and high efficiency site-directed mutagenesis by improvement of the homologous recombination technique. (1995) (24)
- COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms (2021) (24)
- Integration of chicken cytogenetic and genetic maps: 18 new polymorphic markers isolated from BAC and PAC clones. (1998) (24)
- Genome Medicine: past, present and future (2011) (24)
- Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma (2019) (24)
- Reverse transcription in the presence of dideoxynucleotides to increase the sensitivity of expression monitoring with cDNA arrays. (1999) (24)
- Computational analysis of multimorbidity between asthma, eczema and rhinitis (2017) (23)
- STON: exploring biological pathways using the SBGN standard and graph databases (2016) (23)
- Novel genes mapping to the critical region of the 5q- syndrome. (1997) (23)
- Molecular cloning and functional expression of a novel human gene encoding two 41-43 kDa skeletal muscle internal membrane proteins. (1998) (23)
- Histamine‐producing cell‐stimulating activity. A biological activity shared by interleukin 3 and granulocyte‐macrophage colony‐stimulating factor (1987) (23)
- A computational framework for complex disease stratification from multiple large-scale datasets (2018) (23)
- Rfp-Y-like sequences assort independently of pheasant Mhc genes (2004) (22)
- Restriction fragment length polymorphism analysis of major histocompatibility complex class II genes from inbred chicken lines. (2009) (22)
- [IMAGE: molecular integration of the analysis of the human genome and its expression]. (1995) (22)
- Nucleotide sequence of a cloned cDNA corresponding to secreted mu chain of mouse immunoglobulin. (1980) (21)
- Sequence analysis of the human major histocompatibility gene SX alpha (1985) (21)
- Exuberant restriction fragment length polymorphism associated with the DQ alpha-chain gene and the DX alpha-chain gene. (1985) (21)
- Prediction of chronic lung allograft dysfunction: a systems medicine challenge (2014) (20)
- The Human Anatomic Gene Expression Library (H-ANGEL), the H-Inv integrative display of human gene expression across disparate technologies and platforms (2004) (20)
- Analysis of the sheep MHC using HLA class I, II, and C4 cDNA probes (2004) (19)
- Genetic organization of the chicken MHC (1990) (19)
- Nucleotide sequence of constant and 3' untranslated regions of a kappa immunoglobulin light chain mRNA of a homozygous b4 rabbit. (1981) (19)
- Communicating in a public health crisis (2020) (19)
- Mutations in the D strand of the human CD4 V1 domain affect CD4 interactions with the human immunodeficiency virus envelope glycoprotein gp120 and HLA class II antigens similarly. (1991) (19)
- P 4 Medicine needs P 4 Education (2014) (19)
- Linkage of the chicken MHC to the nucleolus organizer region visualized using non-isotopic in situ hybridization. (1991) (19)
- New chicken Rfp-Y haplotypes on the basis of MHC class II RFLP and MLC analyses (1997) (18)
- Integration of Myeloblastosis Associated Virus proviral sequences occurs in the vicinity of genes encoding signaling proteins and regulators of cell proliferation (2006) (17)
- AsthmaMap: An expert‐driven computational representation of disease mechanisms (2018) (17)
- A 1.7-Mb YAC contig around the human BDNF gene (11p13): integration of the physical, genetic, and cytogenetic maps in relation to WAGR syndrome. (1994) (17)
- EpiGeNet: A Graph Database of Interdependencies Between Genetic and Epigenetic Events in Colorectal Cancer (2017) (17)
- Newt: a comprehensive web-based tool for viewing, constructing and analyzing biological maps (2020) (17)
- Mapping of 59 EST gene markers in 31 intervals spanning the human X chromosome. (1997) (16)
- Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort (2018) (16)
- Assignment of the chicken tyrosine hydroxylase gene to chromosome 6 by FISH. (1992) (16)
- Rat immunoglobulin delta heavy chain gene: nucleotide sequence derived from cloned cDNA. (1982) (16)
- Sputum proteomic signature of gastro-oesophageal reflux in patients with severe asthma. (2019) (15)
- Modifications in the myogenic program induced by in vivo and in vitro aging. (2005) (15)
- Introducing PIONEER: a project to harness big data in prostate cancer research (2020) (15)
- Molecular genotyping of four chicken B-complex haplotypes with B-Lβ, B-F, and B-G probes (2004) (14)
- Linkage of a new member of the lectin supergene family to chicken Mhc genes (2004) (14)
- Type 2‐low asthma phenotypes by integration of sputum transcriptomics and serum proteomics (2020) (14)
- Analysis of B complex polymorphism in Rous sarcoma progressor and regressor chickens with B-G, B-F, and B-L beta probes. (1990) (14)
- A prioritization analysis of disease association by data-mining of functional annotation of human genes. (2012) (13)
- Navigating the disease landscape: knowledge representations for contextualizing molecular signatures (2018) (13)
- Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome. (2018) (13)
- Progress in integrative systems biology, physiology and medicine: towards a scale-relative biology (2020) (13)
- Functional Genomics, Proteomics, Metabolomics and Bioinformatics for Systems Biology (2013) (13)
- Regions of homology shared by Rfp-Y and major histocompatibility B complex genes (2004) (13)
- M19 Modulates Skeletal Muscle Differentiation and Insulin Secretion in Pancreatic β-Cells through Modulation of Respiratory Chain Activity (2012) (13)
- Looking back at genomic medicine in 2011 (2012) (13)
- Erratum to: Making sense of big data in health research: towards an EU action plan (2016) (12)
- Are chicken Rfp-Y class I genes classical or non-classical? (2000) (12)
- Alternative usage of 5' exons in the chicken nerve growth factor gene: refined characterization of a weakly expressed gene. (2004) (12)
- Construction of an integrated physical and gene map of human chromosome 20p12 providing candidate genes for Alagille syndrome. (1997) (12)
- A transgenic mouse model engineered to investigate human brain-derived neurotrophic factor in vivo (2007) (12)
- The Evolution and Development of the Universe (2009) (12)
- Chicken Tyrosine Hydroxylase Gene: Isolation and Functional Characterization of the 5′ Flanking Region (1993) (12)
- The Role of Artificial Intelligence in Managing Multimorbidity and Cancer (2021) (12)
- Mapping the βNGF gene in situ to a microchromosome in chicken (1992) (11)
- Sharing knowledge: a new frontier for public-private partnerships in medicine (2009) (11)
- COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (11)
- Instability of sputum molecular phenotypes in U-BIOPRED severe asthma (2020) (11)
- Strategies in cDNA programs. (1993) (10)
- Viva Europa, a Land of Excellence in Research and Innovation for Health and Wellbeing (2017) (10)
- Molecular analysis of chicken immune response genes. (1988) (10)
- Detailed transcript map of a 810-kb region at 11p14 involving identification of 10 novel human 3′ exons (1999) (9)
- Construction of chain- and locus-specific HLA class II DNA probes. Study of HLA-class II transcripts in leukemias. (1986) (9)
- Ten years of Genome Medicine (2019) (9)
- Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux (2019) (9)
- 3.2 A molecular map of the chicken major histocompatibility complex (1989) (9)
- Asthma similarities across ProAR (Brazil) and U-BIOPRED (Europe) adult cohorts of contrasting locations, ethnicity and socioeconomic status. (2019) (8)
- A molecular map of the chicken B complex. (1989) (8)
- Regional assignment of 68 new human gene transcripts on chromosome 11. (1995) (8)
- COVID‐19 Disease Map, a computational knowledge repository of virus‐host interaction mechanisms (2021) (8)
- DNA arrays: methods and applications: report on HUGO Meeting, Tartu, Estonia, 23–26 May, 1999 (2000) (8)
- Global analysis of gene expression in cells of the immune system II. Cell‐free translation products and high‐density filter hybridization data (2000) (8)
- Foreword: from the TRANSCRIPTOME conferences to the SYSTEMOSCOPE international consortium. (2003) (8)
- Cloning and mapping of 5' exons from the gene encoding chicken beta nerve growth factor. (1992) (7)
- Systems medicine, personalized health and therapy. (2015) (7)
- Special Notice to Contributors (1996) (7)
- 2012 highlights in translational 'omics (2013) (7)
- Personalized Clinical Phenotyping through Systems Medicine and Artificial Intelligence (2021) (7)
- Human lymphocyte cDNA ordered library analyzed by 2D gel electrophoresis. 1. Pooling strategy and matching of gel patterns. (1995) (7)
- Functional Annotation: Extracting functional and regulatory order from microarrays (2005) (7)
- Systematic review protocol to define classical IgE-associated diseases from birth to adolescence: the MeDALL study (2012) (7)
- Integrated physical, genetic, and genic map covering 3 Mb around the human NGF gene (NGFB) at 1p13. (1996) (7)
- Automatic quantitation of hybridization signals on cDNA arrays. (2002) (7)
- Competition of HLA-DR and a beta 2 domain peptide for HIV envelope glycoprotein gp120 binding to CD4. (1995) (7)
- Matching Gene Expression with Hypometabolism after Cerebral Ischemia in the Nonhuman Primate (2002) (7)
- Systems Biology (2013) (7)
- Human-like layout algorithms for signalling hypergraphs: outlining requirements (2018) (7)
- Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (7)
- Evolutionary relationship between human and mouse immunoglobulin kappa light chain variable region genes (2004) (7)
- Regional localization of 192 genic markers on human chromosome 1. (1996) (6)
- Characterization of tissue expression and full-length coding sequence of a novel human gene mapping at 3q12.1 and transcribed in oligodendrocytes. (2002) (6)
- Zyxin is up-regulated during megakaryocytic differentiation of human UT-7/c-mpl cells. (2004) (6)
- A minimum of four human class II alpha-chain genes are encoded in the HLA region of chromosome 6. (1983) (6)
- Fem1a is a mitochondrial protein up‐regulated upon ischemia–reperfusion injury (2009) (6)
- Typing of MHC haplotypes in OS chicken by means of RFLP analysis. (1989) (6)
- Clinical and transcriptomic features of persistent exacerbation‐prone severe asthma in U‐BIOPRED cohort (2022) (6)
- On different aspects of network analysis in systems biology (2013) (5)
- Inter-Locus and intea-allelic polymorphisms of HLA class I antigen gene mRNA (2004) (5)
- Human lymphocyte cDNA ordered library analyzed by 2D gel electrophoresis. 3. Analysis of individual clones. (1995) (5)
- INCONSISTENCIES BETWEEN MAPS OF HUMAN CHROMOSOME 22 CORRELATE WITH INCREASED FREQUENCY OF DISEASE-RELATED LOCI (2002) (5)
- Scale Relativity: an Extended Paradigm for Physics and Biology? (2011) (5)
- Molecular basis of T lymphocyte CD4 antigen functions. (1996) (5)
- Sex-linked recombination variation and distribution of disease-related genes. (2005) (5)
- A Topological Data Analysis Network Model of Asthma Based on Blood Gene Expression Profiles (2019) (5)
- Immunohistochemical localisation of nerve growth factor in a subpopulation of chick spinal ganglion neurons (1990) (5)
- Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation (2021) (5)
- The first U-BIOPRED blood handprint of severe asthma (2015) (4)
- Author Correction: Introducing PIONEER: a project to harness big data in prostate cancer research (2020) (4)
- Computational Infrastructures for Data and Knowledge Management in Systems Biology (2013) (4)
- Faculty Opinions recommendation of ARACNE: an algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context. (2006) (4)
- A multi-omics data integration approach to identify a predictive molecular signature of CLAD (2015) (4)
- Autism cornered: network analyses reveal mechanisms of autism spectrum disorders (2014) (4)
- Incorporation of 35 novel gene transcripts into the physical and genetic map of human chromosome 13. (1996) (4)
- COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight (2020) (4)
- Brief Gene Mapping Reports A / B / C / D / E / F / G (2002) (3)
- eTRIKS IT platfroms for large-scale biomedical research (2015) (3)
- The Hallmarks of Cancer Revisited Through Systems Biology and Network Modelling (2011) (3)
- Cohort characteristics and chronic lung allograft dysfunction (CLAD) adjudication in a FP-7 funded project, systems prediction of CLAD (SysCLAD) (2014) (3)
- Issues in Computational Methods for Functional Genomics and Systems Biology (2003) (3)
- The SysCLAD- Systems Prediction of Chronic Lung Allograft Dysfunction Study: Aims, Strategy and First Data (2013) (3)
- AsthmaMap: an interactive knowledge repository for mechanisms of asthma. (2020) (3)
- Sputum transcriptomics reveal up-regulation of IL-1 receptor family members in severe asthma. (2017) (3)
- The Selected Papers of Denis Noble CBE FRS: A Journey in Physiology Towards Enlightenment (2012) (3)
- Clustering analysis of clinical variables in U-BIOPRED adult asthma cohort (2014) (3)
- Analysis of human class II antigen α chain genes: a summary (1983) (3)
- Molecular cloning of the avian beta-nerve growth factor gene: transcription in brain. (1986) (3)
- Late Breaking Abstract - Comparison of the blood transcriptomic profiles of adults and children from the U-BIOPRED asthma study (2017) (2)
- Integrative systems medicine approaches to identify molecular targets in lymphoid malignancies (2016) (2)
- Affinity analysis of differentially expressed genes in hepatocytes expressing HCV core genotype 1b or 3a (2013) (2)
- LSC Abstract – The AsthmaMap: Towards a community-driven reconstruction of asthma-relevant pathways and networks (2016) (2)
- Polymorphism of class II MHC genes in the domestic fowl (1993) (2)
- Correction: Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004) (2)
- Informing epidemic (research) responses in a timely fashion by knowledge management - a Zika virus use case (2020) (2)
- Interaction of CD4 with HLA class II antigens and HIV gp120 (2004) (2)
- Translating systems biology into medical applications : Report of the 3rd Bertinoro Systems Biology Workshop (2009) (2)
- Subject Index, Vol. 77, 1997 (1997) (2)
- Volatile Organic Compounds Breathprinting of U-BIOPRED Severe Asthma smokers/ex-smokers cohort (2017) (2)
- Enabling multiscale modeling in systems medicine: From reactions in cells to organ physiology (2014) (2)
- Assignment of the chicken NOV gene (alias CCN3) to chromosome 2q34-->q36: Conserved and compared synteny between avian, mouse and human. (2002) (2)
- U-BIOPRED accessible handprint: combining omics platforms to identify stable asthma subphenotypes (2018) (2)
- Faculty of 1000 evaluation for Visualization of omics data for systems biology. (2012) (2)
- Extracting functional and regulatory order from microarrays (2005) (2)
- LATE-BREAKING ABSTRACT: Transcriptomic fingerprinting in severe adult-onset asthma shows type2-high and inflammatory-cell gene signatures in the U-BIOPRED cohort (2015) (2)
- Molecular evidence of Group 1 innate lymphoid cell activation in the U-BIOPRED cohort (2017) (2)
- Sequence Analysis of the Human Major Histocompatibility Gene SXa (2003) (1)
- Analysis of five B complex haplotypes with class I (B-F), class II (B-L) and class IV (B-G) probes. (1989) (1)
- Assignment1 of the chicken NOV gene (alias CCN3) to chromosome 2q34→q36: Conserved and compared synteny between avian, mouse and human (2002) (1)
- Analysis of human class II antigen alpha chain genes: a summary. (1983) (1)
- PIONEER: European Commission Innovative Medicines Initiative funded BD4BO (Big data for better outcome) project on prostate cancer (2020) (1)
- Faculty Opinions recommendation of A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome. (2009) (1)
- Fem 1 a is a mitochondrial protein up-regulated upon ischemia – reperfusion injury (2009) (1)
- Molecular Anatomy of the Chicken Major Histocompatibilty B Complex (1989) (1)
- Systems biologists hope for a full integration of their field into cancer research. (2010) (1)
- Effect of thyroliberin on the biosynthesis of poly(A)‐mRNA species in GH3 cells (1981) (1)
- Informing epidemic (research) responses in a timely fashion by knowledge management - a Zika virus use case. (2020) (1)
- Faculty Opinions recommendation of Performance comparison of benchtop high-throughput sequencing platforms. (2012) (1)
- Topological data analysis (TDA) of U-BIOPRED paediatric peripheral blood gene expression identified asthma phenotypes characterised by alternative splicing of glucocorticoid receptor (GR) mRNA (2018) (1)
- Erratum to: Progress in integrative systems biology, physiology and medicine: towards a scale-relative biology (2020) (1)
- Interview with a Thought Leader on Systems Medicine—Charles Auffray, PhD (2018) (1)
- An integrative genomics approach identifies new asthma pathways related to air pollution exposure (2015) (1)
- Participatory medicine: a driving force for revolutionizing healthcare (2013) (1)
- Refined localization of twenty-one genes in subregion p13.1 of human chromosome 1 (2001) (1)
- Unsupervised and externally validated clinical cluster analysis from the U-BIOPRED paediatric cohorts (2018) (1)
- Faculty Opinions recommendation of A comparative study of topology-based pathway enrichment analysis methods. (2020) (1)
- [Molecular models of the interaction between T4 antigen and HLA class II antigens or the LAV virus]. (1986) (1)
- DNA polymorphisms associated with HLA-B-like genes and evidence for a duplication of B40 genes detected with an HLA-B-specific DNA probe. (1987) (1)
- Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms (2018) (1)
- Faculty Opinions recommendation of Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems. (2017) (1)
- Weighted Gene Co-expression Network Analysis of blood paediatric samples from the U-BIOPRED study identifies oxidative stress association with asthma severity (2018) (1)
- Looking back at genomic medicine in 2011 (2012) (1)
- A multi-omics approach to delineate sputum microbiome-associated asthma inflammatory phenotypes (2021) (1)
- Faculty Opinions recommendation of Relationship between clinical signs and transmission of an infectious disease and the implications for control. (2011) (1)
- A versatile and interoperable computational framework for the analysis and modeling of COVID-19 disease mechanisms (2022) (1)
- Informing epidemic (research) responses in a timely fashion by knowledge management – a Zika virus use case (2020) (0)
- From genomic medicine to precision medicine: highlights of 2015 (2016) (0)
- Faculty Opinions recommendation of Identifying a gene expression signature of frequent COPD exacerbations in peripheral blood using network methods. (2015) (0)
- Subject Index Vol. 92, 2001 (2001) (0)
- Geneorganization ofDC andDX subregions ofthehumanmajor histocompatibili ty complex (1985) (0)
- chronic myeloid leukemia apoptosis by imatinib mesylate combined with arsenic trioxide in Coordination of intrinsic, extrinsic, and endoplasmic reticulum-mediated (2008) (0)
- Werner Schmid, 1930–2002 (2002) (0)
- complex mixtures of production method cDNA and applications of these mixtures (1999) (0)
- Faculty Opinions recommendation of The control systems structures of energy metabolism. (2011) (0)
- Systems prediction of chronic lung allograft dysfunction: Results and perspectives from the Cohort of Lung Transplantation and Systems prediction of Chronic Lung Allograft Dysfunction cohorts (2023) (0)
- Erratum to: On Different Aspects of Network Analysis in Systems Biology (2013) (0)
- Distinct pathways underlying neutrophilic inflammation in smoking-associated severe asthma in U-BIOPRED (2017) (0)
- Year : 2009 Computational disease modeling-fact or fiction ? (2010) (0)
- Faculty Opinions recommendation of Integrating personalized gene expression profiles into predictive disease-associated gene pools. (2019) (0)
- Non-invasive urinary lipid mediator excretion profiles identify sub-phenotypes of asthma in the U-BIOPRED study (2016) (0)
- Faculty Opinions recommendation of Differential network biology. (2012) (0)
- PREFACE: INTEGRATIVE STATISTICAL AND COMPUTATIONAL METHODS FOR GENOMICS STUDIES (2002) (0)
- Corrigendum to “Gene expression profiling of human satellite cells during muscular aging using cDNA arrays” [Gene 321 (2003) 145–154] (2004) (0)
- Gregor Mendel at the source of genetics and systems biology (2022) (0)
- Introducing PIONEER : a project to harness big data in prostate cancer 2 research 3 4 (2019) (0)
- The first U-BIOPRED sputum handprint of severe asthma (2015) (0)
- Subtypes of eosinophilic asthma with discrete gene pathway phenotypes (2019) (0)
- Enabling multiscale modeling in systems medicine (2014) (0)
- Progress in integrative systems biology, physiology and medicine: towards a scale-relative biology (2019) (0)
- Faculty Opinions recommendation of DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. (2008) (0)
- Faculty Opinions recommendation of An atlas of gene regulatory networks reveals multiple three-gene mechanisms for interpreting morphogen gradients. (2010) (0)
- COVID-19 and Beyond: A Call for Action and Audacious Solidarity to All the Citizens and Nations, It Is Humanity’s Fight (2020) (0)
- Faculty Opinions recommendation of Identification of highly related references about gene-disease association. (2014) (0)
- Faculty of 1000 evaluation for Leveraging models of cell regulation and GWAS data in integrative network-based association studies. (2012) (0)
- Faculty Opinions recommendation of Dissecting cancer through mathematics: from the cell to the animal model. (2010) (0)
- Faculty Opinions recommendation of Modeling precision treatment of breast cancer. (2014) (0)
- ANALYSIS OF THE RAT 9K VITAMIN D–DEPENDENT CaBP GENE (1987) (0)
- 2012 highlights in translational 'omics (2013) (0)
- Late Breaking Abstract - Longitudinal analysis of variation in clinical features from the U-BIOPRED severe asthma cohort (2018) (0)
- Faculty Opinions recommendation of Integration of multi-omics datasets enables molecular classification of COPD. (2019) (0)
- Combined analysis of gene expression and clinical data in the severe asthma U-BIOPRED cohorts (2014) (0)
- Integration of whole blood genome-wide DNA methylation and gene expression identifies epigenetically controlled modules in relation to NO2 air pollution exposure (2019) (0)
- [Polymorphism of the B locus and capacity for resistance to tumor development]. (1989) (0)
- Gene organization of DC and DX si histocompatibility complex (gene sequences/promoters/DNA-DNA hybridization/HLA antigens (2016) (0)
- The role of inflammation in anxiety and depression in the European U-BIOPRED asthma cohorts (2023) (0)
- Genetic mappingofahumanclass IIantigen ft-chain cDNAclone to theSBregion oftheHLAcomplex (1983) (0)
- Faculty Opinions recommendation of Reductionism and complexity in molecular biology. Scientists now have the tools to unravel biological and overcome the limitations of reductionism. (2005) (0)
- Asthma and Wheeze Severity and the Oropharyngeal Microbiota in Children and Adolescents. (2022) (0)
- Erratum to: Making sense of big data in health research: towards an EU action plan (2016) (0)
- Faculty Opinions recommendation of Interactome networks and human disease. (2011) (0)
- Molecular biology and genetics From functional genomics to systems biology: concepts and practices (2003) (0)
- COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (0)
- Ten years of Genome Medicine (2019) (0)
- Molecular biology and genetics Foreword: from the TRANSCRIPTOMEconferences to the SYSTEMOSCOPEInternational Consortium (2003) (0)
- Faculty Opinions recommendation of Assessing natural variations in gene expression in humans by comparing with monozygotic twins using microarrays. (2005) (0)
- Peptides capable of inhibiting the interactions between viruses and t4 washed cells, products derived therefrom and their applications (1985) (0)
- Faculty Opinions recommendation of Handling missing rows in multi-omics data integration: multiple imputation in multiple factor analysis framework. (2017) (0)
- Mapping the beta NGF gene in situ to a microchromosome in chicken. (1992) (0)
- Theaminoacidsequence andgeneorganization oftheheavychain oftheHLA-DRantigen: Homology toimmunoglobulins (1982) (0)
- Further resolution of non-T2 asthma subtypes from high-throughput sputum transciptomics data in U-BIOPRED (2018) (0)
- HLA-DR Region Proteins and Genes* (1983) (0)
- Faculty Opinions recommendation of Multi-view based integrative analysis of gene expression data for identifying biomarkers. (2020) (0)
- Metagenomic Analysis of Sputum in the U-Biopred Cohort Shows Reduced Diversity in Asthmatics (2019) (0)
- Faculty Opinions recommendation of Prediction of the P. falciparum target space relevant to malaria drug discovery. (2013) (0)
- ADEPT-derived, U-BIOPRED validated asthma clinical clusters with Th2 and non-Th2 phenotypes (2014) (0)
- Integrative systems medicine approaches to identify molecular targets in lymphoid malignancies (2016) (0)
- Computational Methods and Bioinformatic Tools (2004) (0)
- Towards a systems approach for chronic diseases, based on (2017) (0)
- The Class II Molecules of the Review Human and Murine Major Histocompatibility Complex (2004) (0)
- Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers (2018) (0)
- Faculty Opinions recommendation of Towards a proteome-scale map of the human protein-protein interaction network. (2006) (0)
- LSC Abstract – Eicosanoids in asthma: Multi-omics data interpretation (2016) (0)
- Faculty Opinions recommendation of Multi-omic tumor data reveal diversity of molecular mechanisms that correlate with survival. (2018) (0)
- COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight [version 1; peer review: 3 approved with reservations] (2021) (0)
- The electron as a self-organising entity in physics and biology. (2022) (0)
- Primary transcription map of the critical region of the 5q-syndrome. (1996) (0)
- Characterization of the Lymphocyte Activation Gene 3Encoded 3Encoded 3Encoded Protein . A New Ligand for Human Leukoc 3 ~ Antigen Class H Antigens By (2003) (0)
- Faculty Opinions recommendation of Tumour evolution inferred by single-cell sequencing. (2011) (0)
- GraphML-SBGN bidirectional converter for metabolic networks (2022) (0)
- Faculty Opinions recommendation of A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model. (2007) (0)
- Major histocompatibility complex class II antigens: genes and proteins. (1986) (0)
- Faculty Opinions recommendation of Data integration in the era of omics: current and future challenges. (2019) (0)
- Polymorphism andcomplexity ofthehumanDC andmurine I-Acxchain genes (1983) (0)
- Gene set variation analysis of mRNA expression in bronchial biopsies from the U-BIOPRED asthma study (2014) (0)
- TRACE: Tennessee Research and Creative TRACE: Tennessee Research and Creative Exchange Exchange Bridging the gap between systems biology and medicine Bridging the gap between systems biology and medicine (2022) (0)
- Understanding Pulmonary Diseases An Integrative Systems Biology Approach to (2010) (0)
- Making sense of big data in health research: Towards an EU action plan (2016) (0)
- Morse-clustering of a Topological Data Analysis Network Identifies Phenotypes of Asthma Based on Blood Gene Expression Profiles (2019) (0)
- Faculty Opinions recommendation of An integrative genomics approach to infer causal associations between gene expression and disease. (2007) (0)
- Nucleotide sequence of constant and 3 ' untranslated regions of a Kc immunoglobulin light chain mRNA of a homozygous b 4 rabbit ( hyperimmunization / spleen / in vitro translation / gene cloning (0)
- Erratum to: Progress in integrative systems biology, physiology and medicine: towards a scale-relative biology (2020) (0)
- Region Divergent Specialization in Antigen Binding Transcribed , Polymorphic , and Shows Gene Cluster in the Chicken , Is MHC ) , the Second Rfp-Y Fragment Pattern-Y ( At Least One Class I Gene in Restriction (2001) (0)
- Faculty Opinions recommendation of g:Profiler-a web server for functional interpretation of gene lists (2016 update). (2016) (0)
- Faculty Opinions recommendation of Identification of aberrant pathways and network activities from high-throughput data. (2012) (0)
- Faculty Opinions recommendation of Next-Generation Machine Learning for Biological Networks. (2019) (0)
- COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight [version 1; peer review: awaiting peer review] (2020) (0)
- Welcome to Progress in Preventive Medicine from the Editorial Board (2016) (0)
- Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (0)
- F1000Prime recommendation of How to make more published research true. (2014) (0)
- Research Repor t Automatic Quantitation of Hybridization Signals on cDNA Array s (2002) (0)
- Faculty Opinions recommendation of Statistical Modeling: The Two Cultures (with comments and a rejoinder by the author). (2017) (0)
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What Schools Are Affiliated With Charles Auffray?
Charles Auffray is affiliated with the following schools:
