Charles Frederick George

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#10437

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#14300

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#7341

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#9072

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Philosophy

Why Is Charles Frederick George Influential?

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According to Wikipedia, Sir Charles Frederick George is an English physician and academic. George was born in Birmingham to William Hubert George and Evelyn Pryce, and was educated in Oundle. He graduated from Birmingham University with an Intercalated BSc in Anatomy in 1962, and a MBChB in Medicine in 1965.

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Charles Frederick George's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Absorption and metabolism of nicotine from cigarettes. (1975) (322)
Increased sensitivity to nitrazepam in old age. (1977) (311)
SLEEP APNOEA PATIENTS HAVE MORE AUTOMOBILE ACCIDENTS (1987) (289)
The effect of ageing on the hepatic clearance of propranolol. (1979) (244)
Resistance to β‐adrenoceptor stimulants (a possible explanation for the rise in asthma deaths) (1971) (199)
Compliance with tricyclic antidepressants: the value of four different methods of assessment. (2000) (184)
The benefits of prescription information leaflets (1). (1989) (164)
Factors affecting the absolute bioavailability of nifedipine. (1995) (138)
Age-related changes in the pharmacokinetics and pharmacodynamics of nifedipine. (1988) (130)
Drug-induced rhabdomyolysis--mechanisms and management. (1993) (119)
The first pass metabolism of nifedipine in man. (1984) (111)
The effect of age on the pharmacokinetics of levodopa administered alone and in the presence of carbidopa. (1989) (110)
Prescription information leaflets: a pilot study in general practice. (1983) (110)
Intravenously administered isoproterenol sulfate dose-response curves in man. (1972) (107)
Quercetin, an in vitro inhibitor of CYP3A, does not contribute to the interaction between nifedipine and grapefruit juice. (1993) (103)
Prescription Information Leaflets: A National Survey (1990) (97)
Drug Metabolism by the Gastrointestinal Mucosa (1981) (92)
Imipramine--a possible alternative to current therapy for urinary incontinence in the elderly. (1981) (83)
Knowledge of and attitudes to medicines in the Southampton community. (1986) (74)
Drug Kinetics and Hepatic Blood Flow (1979) (73)
The influence of levodopa on gastric emptying in man. (1990) (72)
The influences of dose and ethnic origins on the pharmacokinetics of nifedipine (1993) (62)
Ethnic differences in the pharmacokinetics of oral nifedipine. (1991) (62)
Metabolism of isoprenaline in the intestine (1974) (61)
Sulindac metabolism: The importance of an intact colon (1985) (59)
The reduction of sulphinpyrazone and sulindac by intestinal bacteria. (1987) (59)
The Teratogenic Metabolites of Vitamin A in Women Following Supplements and Liver (1994) (59)
The benefits of prescription information leaflets (2). (1989) (57)
Assessment of selective β‐adrenoceptor blockade in man (1973) (55)
The pharmacokinetics of oral nifedipine--a population study. (1988) (49)
The influence of protein containing meals on the pharmacokinetics of levodopa in healthy volunteers. (1991) (47)
The role of the gut flora in the reduction of sulphinpyrazone in the rat. (1982) (44)
A SECOND LOOK AT EMEPRONIUM BROMIDE IN URINARY INCONTINENCE (1977) (44)
Metabolism of terbutaline in man and dog. (1974) (44)
The effect of monoamine oxidase inhibitors on 'first-pass' metabolism of tyramine in dog intestine. (1980) (40)
The influence of levodopa on gastric emptying in healthy elderly volunteers (1992) (40)
The trans-hepatic extraction of nifedipine. (1987) (36)
The influence of posture on the pharmacokinetics of orally administered nifedipine. (1992) (35)
Comparison of the potassium- retaining effects of amiloride and spironolactone in hypertensive patients with thiazide-induced hypokalaemia. (1973) (35)
Pharmacology of propranolol in patients with cirrhosis and portal hypertension. (1985) (35)
Reduced respiratory responses to carbon dioxide after propranolol: a central action. (1976) (33)
Value of routine electrocardiography in hypertensive patients. (1972) (33)
Practolol in Treatment of Angina Pectoris. A Double-blind Trial (1970) (32)
Role of the gut flora in the reduction of sulfinpyrazone in humans. (1984) (31)
Elimination of drugs by active intestinal transport (1979) (29)
Anticholinergic drugs in the treatment of airways disease. (1985) (28)
The metabolism of cyclamate to cyclohexylamine and its cardiovascular consequences in human volunteers. (1992) (27)
The role of the gut flora in the reduction of sulphoxide containing drugs. (1986) (26)
The effects of food and posture on the pharmacokinetics of a biphasic release preparation of nifedipine. (1986) (25)
Cardiovascular reflexes in Parkinsonism. (1971) (25)
Clinical Consequences of Abrupt Drug Withdrawal (1987) (24)
ALLERGY TO AMINOPHYLLINE (1983) (23)
Trial of combination of guanethidine and oxprenolol in hypertension. (1976) (23)
The site of reduction of sulphinpyrazone in the rabbit. (1984) (21)
Medication for the Elderly (1984) (21)
A comparison of once and twice daily atenolol in hypertension. (1977) (21)
Food and nifedipine pharmacokinetics. (1987) (20)
The action of L(-)-dopa on baroreflexes in Parkinsonism. (1972) (19)
Amiloride handling in renal failure. (1980) (19)
Gastric emptying in healthy volunteers after multiple doses of levodopa. (1991) (19)
The electrocardiographic and anticholinergic effects of trazodone and imipramine in man (2004) (18)
Pharmacokinetics of dextro-, leavo- and racemic propranolol in man (1972) (18)
Salmonella meningitis following treatment of enteritis with neomycin. (1984) (17)
The design of prescription information leaflats and feasibility of their use in general practice (1987) (16)
The assessment of potential drug interactions with a new tricyclic antidepressant drug. (1974) (16)
The effect of an hypnotic with a short half-life on hangover effect in old patients. (1978) (16)
Drug therapy in old age (1998) (15)
Contribution of individual differences in gastric emptying to variability in plasma propranolol concentrations. (1978) (14)
Microbial Amino Acid Metabolites and Bladder Cancer: No Evidence of Promoting Activity in Man (1988) (13)
Drugs Causing Intestinal Obstruction: A Review 1 (1980) (13)
Slow release nifedipine plus atenolol in chronic stable angina pectoris. (1989) (13)
Acebutolol pharmacokinetics in renal failure. (1983) (13)
Assessment of selective beta-adrenoceptor blockade in man. (1973) (13)
Food, drugs, and bioavailability. (1984) (12)
PORTAL HYPERTENSION, PROPRANOLOL, AND HEPATIC ENCEPHALOPATHY (1982) (12)
A Trial of the Combination of Guanethidine and Oxprenolol in Hypertension (1974) (12)
Medicine taking in Southampton: a second look. (1996) (12)
Digitalis intoxication: a new approach to an old problem. (1983) (12)
Problems in assessing beta-adrenoceptor antagonism in man. (1975) (11)
Clinical pharmacology. Drug development. (1980) (11)
The absorption and conjugation of methyldopa in patients with coeliac and Crohn's diseases during treatment. (1983) (10)
Increased sensitivity to benzodiazepines in the elderly (1979) (10)
Acquired resistance to beta stimulants: a possible explantion for the rise in the asthma death rate in Britain. (1973) (10)
Pharmacology of M & B 17803A in man and dog. (1971) (10)
Ampoules, infusions, and filters. (1986) (10)
Telling patients about their medicines. (1987) (10)
Drug and therapeutics committees and information pharmacy services: The United Kingdom (1983) (9)
Hypotension in response to iloprost, a prostacyclin analogue. (1986) (9)
Oral amino acids and gastric emptying: an investigation of the mechanism of levodopa-induced gastric stasis. (1991) (9)
Interactions with digoxin: more problems. (1982) (9)
Hypocretin (orexin) pathway to sleep (2000) (9)
Intravenous propranolol in patients with inflammation. (1982) (8)
Factors affecting the pharmacokinetics of nifedipine (2004) (8)
Class II antiarrhythmic agents. (1988) (8)
Diseases of the alimentary system. Absorption, distribution, and metabolism of drugs; effects of disease of the gut. (1976) (8)
Quinidine and the non‐renal elimination of digoxin (1982) (7)
Hemodynamic responses of trazodone and impramine (1982) (7)
Are Hypnotics Helpful or Harmful to Elderly Patients? (1979) (7)
A crossover comparison of clonidine and methyldopa in hypertension (1972) (6)
CAN ADVERSE DRUG REACTIONS BE PREVENTED? (1980) (6)
Adverse drug reactions and secrecy. (1992) (6)
Effects of Ischaemic Heart Disease, Crohn’s Disease and Antimicrobial Therapy on the Pharmacokinetics of Sulphinpyrazone (1986) (5)
Bradyarrhythmia complicating myocardial infarction. (1968) (5)
EMEPRONIUM BROMIDE IN URINARY INCONTINENCE (1977) (5)
A comparison of propranolol and compound RO3-4787 in the treatment of arterial hypertension in man. (1975) (5)
Contribution of the liver to overall elimination of propranolol (1976) (5)
Levodopa and pressor amine sensitivity in parkinsonism (1972) (5)
Topics in Clinical Pharmacology (1980) (5)
Bronchiolitis Obliterans Secondary to Amiodarone (1993) (5)
Report on Round Table on renin suppression and the hypotensive action of beta-adrenergic-blocking drugs. (1975) (5)
Chlormethiazole--no hangover effect but not an ideal hypnotic for the young. (1979) (4)
Adrenergic blockade in hypertension. (1972) (4)
Clinical evaluation of indoramin, a new antihypertensive agent (1973) (4)
Circulatory effects of intravenous tyramine and noradrenalin in Parkinsonism. (1972) (4)
Propranolol absorption. (1977) (4)
Clinical Pharmacy and Hospital Drug Management (1982) (4)
Oxprenolol in Parkinsonism (1975) (4)
Drugs in old age: new perspectives. (1990) (4)
Presystemic drug metabolism in the liver (1982) (4)
Pharmacokinetics of methyldopa in gastrointestinal disease [proceedings]. (1980) (3)
The importance of clinical pharmacology in drug development. (1981) (3)
The effect of selective cardiac adrenergicβ-blockade on the hypotensive effect of hydrallazine (1971) (3)
Beta-adrenoceptor antagonists plus nifedipine in the treatment of chronic stable angina pectoris (1989) (3)
TELLING PATIENTS ABOUT THEIR MEDICINES (1987) (3)
Resistance to beta-adrenoceptor stimulants and death from bronchial asthma. (1971) (2)
Education of medical students in relation to drug development, safety and efficacy (1985) (2)
Cardiovascular reflex activity in Parkinsonism. (1971) (2)
First-pass metabolism by the lung: introduction (1982) (2)
Cardiac rehabilitation : results of a national survey (2005) (2)
Hepatic clearance of propranolol in dogs. (1973) (2)
Induction of bronchial beta-adrenergic receptor resistance in normal man [proceedings]. (1977) (1)
Methods for distinguishing between the various sites of first-pass metabolism in man (1982) (1)
A comparison of isoxicam pharmacokinetics in young and elderly subjects. (1986) (1)
Comparison of the effects of atenolol and practolol on exercise tachycardia in normal subjects. (1976) (1)
BJCP 25th anniversary (2001) (1)
Nifedipine: a calcium channel blocking drug. (1987) (1)
Package inserts. (1992) (1)
Effect of β‐adrenoceptor antagonists on the decline of the chronotropic response to isoprenaline (1972) (1)
The effect of selective cardiac beta adrenergic blockade on the hypotensive effect of hydralazine (1970) (1)
The clinical effects and cost-avoidance of a change in perioperative bronchodilator use. (1994) (1)
Drugs causing gastrointestinal obstruction. (1993) (1)
Textbook of Adverse Drug Reactions. Fourth Edition: Edited by D. M. Davies Published 1991 Oxford University Press, Oxford 879 pages ISBN 0 19 262045 2 £95.00 (1992) (1)
Advertising Medicines to the Public (1996) (1)
Isoxicam: the evolving perspective. Papers presented at a symposium. Sydney, NSW, Australia, 19 May 1985. (1986) (0)
A method for studying drug metabolism in the canine intestine (T) (1974) (0)
Pharmacology ofpropranolol inpatients withcirrhosis andportal hypertension (1985) (0)
Inter-individual differences in response to cardiovascular drug therapy. (1988) (0)
S. R. Moore and T. W. Teal (eds), Geriatric Drug Use – Clinical and Social Perspectives , Pergamon Press, Oxford, 1985, 222 pp., $35, ISBN 0 08 031 939 4. (1986) (0)
Rapid identification of drugs in cases of self poisoning by means of combined GC-MS-Computer system (T). (1972) (0)
Risk-benefit decisions in human administration (1987) (0)
Atlas of Drug Reactions (1987) (0)
Textbook of Adverse Drug Reactions (1992) (0)
Changes in baroreflexes induced by L-dopa. (1972) (0)
Lithium and the kidney. (1984) (0)
A comparison ofonceandtwice daily atenolol inhypertension (1977) (0)
Medicines: Regulation, Research and Risk (1993) (0)
LOW-DOSE ORAL PROPRANOLOL (1978) (0)
Treatment of insomnia (2002) (0)
Theinfluence ofposture on thepharmacokinetics oforally administered nifedipine (1992) (0)
Prescriptions: Placebo, Poison or Panacea? (1979) (0)
Propranolol (1972) (0)
2298 – ALTERED PHARMACOKINETICS OF PROPRANOLOL IN OLD AGE (1978) (0)
Therapeutic focus, Nifedipine: a calcium channel blocking drug (1987) (0)
Treatment of insomnia. Author's reply (2002) (0)
Chlormethiazole - nohangover effect butnotanideal hypnotic fortheyoung (1979) (0)
Printed in the U . S . A . BETA-ADRENOCEPTOR ANTAGONISTS PLUS NIFEDIPINE IN THE TREATMENT OF CHRONIC STABLE ANGINA PECTORIS (0)
ACEBUTOLOL PHARMACOKINETICSINRENAL FAILURE (1983) (0)
Clinics in Obstetrics and Gynaecology. Vol. 13, no. 2, June 1986. Prescribing in Pregnancy (1987) (0)
Adverse effects of beta-adrenoceptor antagonists on the kidney. (1985) (0)
Ethnic differences inthepharmacokinetics oforalnifedipine (1991) (0)
ADVERSE DRUG REACTIONS AND SECRECY : KNOWLEDGE IS POWER; DOCTORS SHOULD CEDE SOME OF BOTH TO THEIR PATIENTS (1992) (0)
Sulphinpyrazone Metabolism: A Gut Reaction (1983) (0)

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