Charles G. Glabe
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Charles G. Glabebiology Degrees
Biology
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Biochemistry
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Biology
Charles G. Glabe's Degrees
- PhD Biochemistry University of California, Irvine
- Bachelors Biochemistry University of California, Davis
Why Is Charles G. Glabe Influential?
(Suggest an Edit or Addition)Charles G. Glabe's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis (2003) (3868)
- A specific amyloid-β protein assembly in the brain impairs memory (2006) (2572)
- Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo* (2005) (2042)
- Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state (1993) (1436)
- A specific amyloid-beta protein assembly in the brain impairs memory. (2006) (1267)
- Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers*♦ (2005) (979)
- Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs. (1992) (977)
- Permeabilization of Lipid Bilayers Is a Common Conformation-dependent Activity of Soluble Amyloid Oligomers in Protein Misfolding Diseases* (2004) (856)
- In vitro aging of ß-amyloid protein causes peptide aggregation and neurotoxicity (1991) (812)
- Structural Classification of Toxic Amyloid Oligomers* (2008) (755)
- Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder. (1996) (723)
- Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers (2007) (709)
- Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction. (1999) (708)
- Small Molecule Inhibitors of Aggregation Indicate That Amyloid β Oligomerization and Fibrillization Pathways Are Independent and Distinct* (2007) (678)
- Structure‐Activity Analyses of β‐Amyloid Peptides: Contributions of the β25–35 Region to Aggregation and Neurotoxicity (1995) (646)
- Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril (2016) (625)
- Common mechanisms of amyloid oligomer pathogenesis in degenerative disease (2006) (576)
- Atomic View of a Toxic Amyloid Small Oligomer (2012) (514)
- Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis (2006) (371)
- Temporal Profile of Amyloid-β (Aβ) Oligomerization in an in Vivo Model of Alzheimer Disease (2006) (348)
- Structural and Dynamic Features of Alzheimer's Aβ Peptide in Amyloid Fibrils Studied by Site-directed Spin Labeling* (2002) (345)
- A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric Aβ, and Frank Neuronal Loss (2013) (344)
- Annular Protofibrils Are a Structurally and Functionally Distinct Type of Amyloid Oligomer* (2009) (334)
- Prion-Like Behavior and Tau-dependent Cytotoxicity of Pyroglutamylated β-Amyloid (2012) (329)
- beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain. (1994) (327)
- Acceleration of Amyloid Fibril Formation by Specific Binding of Aβ-(1–40) Peptide to Ganglioside-containing Membrane Vesicles* (1997) (315)
- Heat‐shock protein 70 modulates toxic extracellular α‐synuclein oligomers and rescues trans‐synaptic toxicity (2011) (299)
- Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures. (1991) (291)
- Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis. (2004) (277)
- Accumulation of Toxic α-Synuclein Oligomer within Endoplasmic Reticulum Occurs in α-Synucleinopathy In Vivo (2012) (268)
- Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity. (1995) (247)
- Surfactant properties of Alzheimer's A beta peptides and the mechanism of amyloid aggregation. (1994) (243)
- Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/beta protein. (1992) (236)
- Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology. (2006) (232)
- In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. (1991) (229)
- Tau-dependent microtubule disassembly initiated by prefibrillar β-amyloid (2006) (226)
- Methylene blue inhibits amyloid Abeta oligomerization by promoting fibrillization. (2007) (218)
- Biosynthetic site-specific incorporation of a non-natural amino acid into a polypeptide (1989) (218)
- Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid (2008) (217)
- Soluble Amyloid Oligomers Increase Bilayer Conductance by Altering Dielectric Structure (2006) (217)
- In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor (1993) (211)
- Single Particle Characterization of Iron-induced Pore-forming α-Synuclein Oligomers* (2008) (206)
- Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer’s disease (2001) (204)
- Soluble Amyloid Aβ-(1–40) Exists as a Stable Dimer at Low Concentrations* (1997) (201)
- β-Amyloid protein promotes neuritic branching in hippocampal cultures (1990) (196)
- Metabolite-initiated protein misfolding may trigger Alzheimer's disease. (2004) (192)
- Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers. (2006) (192)
- Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer’s disease (2018) (190)
- Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway. (2010) (188)
- Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity. (2014) (187)
- Distinct Early Folding and Aggregation Properties of Alzheimer Amyloid-β Peptides Aβ40 and Aβ42 (2006) (181)
- Protein misfolding, congophilia, oligomerization, and defective amyloid processing in preeclampsia (2014) (176)
- Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-b (2012) (173)
- Amyloid-peptide vaccinations reduce {beta}-amyloid plaques but exacerbate vascular deposition and inflammation in the retina of Alzheimer's transgenic mice. (2009) (172)
- Toxic Human Islet Amyloid Polypeptide (h-IAPP) Oligomers Are Intracellular, and Vaccination to Induce Anti-Toxic Oligomer Antibodies Does Not Prevent h-IAPP–Induced β-Cell Apoptosis in h-IAPP Transgenic Mice (2007) (168)
- Conformation-dependent antibodies target diseases of protein misfolding. (2004) (167)
- Conformation-dependent anti-amyloid oligomer antibodies. (2006) (167)
- Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates (2012) (165)
- ERK1/2 Activation Mediates Aβ Oligomer-induced Neurotoxicity via Caspase-3 Activation and Tau Cleavage in Rat Organotypic Hippocampal Slice Cultures* (2006) (164)
- Inhibition of human IAPP fibril formation does not prevent beta-cell death: evidence for distinct actions of oligomers and fibrils of human IAPP. (2006) (161)
- The species-specific egg receptor for sea urchin sperm adhesion is EBR1,a novel ADAMTS protein. (2003) (154)
- Fibrillar Oligomers Nucleate the Oligomerization of Monomeric Amyloid β but Do Not Seed Fibril Formation* (2009) (150)
- Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers (2010) (146)
- Carbohydrate specificity of sea urchin sperm bindin: a cell surface lectin mediating sperm-egg adhesion (1982) (144)
- Soluble and mature amyloid fibrils in drusen deposits. (2010) (141)
- Preparation and properties of fluorescent polysaccharides. (1983) (139)
- Egg surface glycoprotein receptor for sea urchin sperm bindin. (1978) (134)
- Species specific agglutination of eggs by bindin isolated from sea urchin sperm (1977) (134)
- Intracellular Aβ1-42 Aggregates Stimulate the Accumulation of Stable, Insoluble Amyloidogenic Fragments of the Amyloid Precursor Protein in Transfected Cells (*) (1995) (128)
- Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid‐β oligomers (2010) (126)
- Binding of Zn(II), Cu(II), and Fe(II) ions to Alzheimer's A beta peptide studied by fluorescence. (1999) (126)
- Amyloid-β Annular Protofibrils Evade Fibrillar Fate in Alzheimer Disease Brain*♦ (2011) (124)
- Preferential adsorption, internalization and resistance to degradation of the major isoform of the Alzheimer's amyloid peptide, Aβ1–42, in differentiated PC12 cells (1997) (112)
- Cell surface APP751 forms complexes with protease nexin 2 ligands and is internalized via the low density lipoprotein receptor-related protein (LRP) (1996) (110)
- Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy. (2005) (108)
- Soluble Aβ oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in Alzheimer's disease brain (2005) (104)
- Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model (2013) (103)
- Monoclonal Antibodies against Aβ42 Fibrils Distinguish Multiple Aggregation State Polymorphisms in Vitro and in Alzheimer Disease Brain* (2014) (97)
- Protective Effect of Geranylgeranylacetone via Enhancement of HSPB8 Induction in Desmin-Related Cardiomyopathy (2009) (96)
- Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity (1999) (92)
- Methylene Blue Modulates Huntingtin Aggregation Intermediates and Is Protective in Huntington's Disease Models (2012) (92)
- Site-specific incorporation of nonnatural residues during in vitro protein biosynthesis with semisynthetic aminoacyl-tRNAs. (1991) (90)
- Glycosylation of ovalbumin nascent chains. The spatial relationship between translation and glycosylation. (1980) (90)
- Anti-Aβ1–11 Antibody Binds to Different β-Amyloid Species, Inhibits Fibril Formation, and Disaggregates Preformed Fibrils but Not the Most Toxic Oligomers* (2007) (86)
- Hsp70 and Hsp40 Functionally Interact with Soluble Mutant Huntingtin Oligomers in a Classic ATP-dependent Reaction Cycle* (2010) (86)
- Multivalent Binding of Complement Protein C1q to the Amyloid β-Peptide (Aβ) Promotes the Nucleation Phase of Aβ Aggregation (1995) (84)
- Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity (2016) (84)
- Synaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases. (2016) (83)
- The contribution of orchid mycorrhizal fungi to seed germination: a speculative review. (1990) (79)
- CD45 Deficiency Drives Amyloid-β Peptide Oligomers and Neuronal Loss in Alzheimer's Disease Mice (2011) (78)
- Isolation and characterization of the vitelline layer of sea urchin eggs (1977) (78)
- Pore-Forming Proteins Share Structural and Functional Homology with Amyloid Oligomers (2007) (77)
- Liposomes containing colloidal gold are a useful probe of liposome-cell interactions. (1983) (76)
- Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer’s pathology (2017) (75)
- Familial Alzheimer's Disease Mutations within the Amyloid Precursor Protein Alter the Aggregation and Conformation of the Amyloid-β Peptide* (2017) (75)
- Exercise reverses preamyloid oligomer and prolongs survival in αB-crystallin-based desmin-related cardiomyopathy (2007) (73)
- Distinct early folding and aggregation properties of Alzheimer amyloid-beta peptides Abeta40 and Abeta42: stable trimer or tetramer formation by Abeta42. (2006) (71)
- Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix. (1999) (70)
- Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques (2014) (69)
- Amyloid-beta peptide and oligomers in the brain and cerebrospinal fluid of aged canines. (2010) (68)
- Membrane Fusion Is Induced by a Distinct Peptide Sequence of the Sea Urchin Fertilization Protein Bindin* (1998) (66)
- Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes (2013) (65)
- Oxidation of Aβ and Plaque Biogenesis in Alzheimer's Disease and Down Syndrome (2001) (61)
- Structure/function analysis of the sea urchin sperm adhesive protein bindin. (1993) (58)
- Structural differences between amyloid beta oligomers. (2016) (57)
- Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin (2008) (57)
- Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro. (2006) (57)
- Structure-based inhibitors of amyloid beta core suggest a common interface with tau (2019) (53)
- Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces behavioral and Aβ pathology and modulates Aβ oligomerization (2015) (53)
- Toxicity of Pyroglutaminated Amyloid β‐Peptides 3(pE)‐40 and ‐42 Is Similar to That of Aβ1‐40 and ‐42 (1999) (53)
- Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse (2014) (51)
- Anti-A beta 1-11 antibody binds to different beta-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils but not the most toxic oligomers. (2007) (50)
- A Conformation Change in the Carboxyl Terminus of Alzheimer's Aβ(1–40) Accompanies the Transition from Dimer to Fibril as Revealed by Fluorescence Quenching Analysis* (2000) (47)
- Soluble Abeta oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in Alzheimer's disease brain. (2005) (44)
- Huntington's disease cerebrospinal fluid seeds aggregation of mutant huntingtin (2015) (44)
- Isolation of a high molecular weight glycoconjugate derived from the surface of S purpuratus eggs that is implicated in sperm adhesion. (1981) (42)
- Transgenic mice as a model of pre-clinical Alzheimer's disease. (2011) (41)
- Effect of Synthetic Aβ Peptide Oligomers and Fluorinated Solvents on Kv1.3 Channel Properties and Membrane Conductance (2012) (40)
- Does Alzheimer disease tilt the scales of amyloid degradation versus accumulation? (2000) (39)
- Reversible disruption of cultured endothelial monolayers by sulphated fucans. (1983) (39)
- Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors (2017) (39)
- Amyloid beta protein is internalized selectively by hippocampal field CA1 and causes neurons to accumulate amyloidogenic carboxyterminal fragments of the amyloid precursor protein. (1998) (38)
- Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice (2012) (38)
- A fucan specific lectin on teratocarcinoma stem cells. (1981) (36)
- Effective anti-Alzheimer Aβ therapy involves depletion of specific Aβ oligomer subtypes (2016) (36)
- Dityrosine Cross-Linked Aβ Peptides: Fibrillar β-Structure in Aβ(1-40) Is Conducive to Formation of Dityrosine Cross-Links but a Dityrosine Cross-Link in Aβ(8-14) Does Not Induce β-Structure (2003) (35)
- The sequence of the Arbacia punctulata bindin cDNA and implications for the structural basis of species-specific sperm adhesion and fertilization. (1991) (34)
- A rapidly diverging EGF protein regulates species-specific signal transduction in early sea urchin development. (2000) (33)
- Evidence for Proteotoxicity in Cells in Type 2 Diabetes (2010) (33)
- Oxidation of Abeta and plaque biogenesis in Alzheimer's disease and Down syndrome. (2001) (33)
- Novel Aβ peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease (2005) (32)
- Epitomic Characterization of the Specificity of the Anti-Amyloid Aβ Monoclonal Antibodies 6E10 and 4G8 (2018) (32)
- Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules. (2012) (32)
- Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure (2018) (30)
- THE EFFECT OF SOLUBLE EGG JELLY ON THE FERTILIZABILITY OF ACID‐DEJELLIED SEA URCHIN EGGS * (1979) (30)
- Identification of a 97-kDa heat shock protein from S. franciscanus ovaries with 94% amino acid identity to the S. purpuratus egg surface receptor for sperm. (1997) (30)
- Studies on the interactions of sperm with the surface of the sea urchin egg. (1981) (30)
- Amyloid Beta Annular Protofibrils in Cell Processes and Synapses Accumulate with Aging and Alzheimer-Associated Genetic Modification (2009) (29)
- Presenilin-1 Immunoreactivity Is Localized Intracellularly in Alzheimer's Disease Brain, but Not Detected in Amyloid Plaques (1997) (28)
- Cultured cell and transgenic mouse models for tau pathology linked to β-amyloid (2005) (27)
- Poloxamer 188 copolymer membrane sealant rescues toxicity of amyloid oligomers in vitro. (2009) (27)
- Reactive γ-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells. (2015) (26)
- Bindin, a multifunctional sperm ligand and the evolution of new species (1994) (26)
- CNI-1493 inhibits Aβ production, plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease (2008) (25)
- Aβ aggregation profiles and shifts in APP processing favor amyloidogenesis in canines (2012) (24)
- Multivalent binding of complement protein C1Q to the amyloid beta-peptide (A beta) promotes the nucleation phase of A beta aggregation. (1995) (24)
- Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4. (2019) (23)
- Glycosylation of Ovalbumin Nascent Chains (1980) (22)
- Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers. (2012) (22)
- Toxicity of pyroglutaminated amyloid beta-peptides 3(pE)-40 and -42 is similar to that of A beta1-40 and -42. (1999) (20)
- Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer’s APP/PSEN1 mice by gene targeting of diabetes/Alzheimer’s-related Sorcs1 (2016) (20)
- A sparse matrix screen to establish initial conditions for protein renaturation. (1995) (19)
- Heterodivalent linked macrocyclic β-sheets with enhanced activity against Aβ aggregation: two sites are better than one. (2012) (19)
- Hypertension Is Associated With Preamyloid Oligomers in Human Atrium: A Missing Link in Atrial Pathophysiology? (2014) (18)
- Age-Related Intraneuronal Aggregation of Amyloid-β in Endosomes, Mitochondria, Autophagosomes, and Lysosomes (2019) (18)
- The influence of the carboxyl terminus of the Alzheimer Aβ peptide on its conformation, aggregation, and neurotoxic properties (2002) (17)
- Oligomeric proteins ultrastructurally localize to cell processes, especially to axon terminals with higher density, but not to lipid rafts in Tg2576 mouse brain (2005) (17)
- Amyloid Oligomer Structures and Toxicity (2009) (17)
- Cultured cell and transgenic mouse models for tau pathology linked to beta-amyloid. (2005) (14)
- Nonhuman Amyloid Oligomer Epitope Reduces Alzheimer’s-Like Neuropathology in 3xTg-AD Transgenic Mice (2013) (13)
- Dityrosine cross-linked Abeta peptides: fibrillar beta-structure in Abeta(1-40) is conducive to formation of dityrosine cross-links but a dityrosine cross-link in Abeta(8-14) does not induce beta-structure. (2003) (13)
- Quantitative Imaging of Preamyloid Oligomers, a Novel Structural Abnormality, in Human Atrial Samples (2014) (13)
- Amyloid Oligomer Structures and Toxicity~!2009-04-30~!2009-07-07~!2010-01-02~! (2010) (13)
- Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus (2019) (11)
- Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease (2020) (11)
- DISTINCT EARLY FOLDING AND AGGREGATION PROPERTIES OF ALZHEIMER AMYLOID-ß PEPTIDE Aß40 AND Aß42: STABLE TRIMER OR TETRAMER FORMATION BY Aß42. (2006) (10)
- SPERM‐EGG BINDING EVENTS DURING SEA URCHIN FERTILIZATION * (1982) (9)
- Conformation-Dependent Oligomers in Cerebrospinal Fluid of Presymptomatic Familial Alzheimer's Disease Mutation Carriers (2012) (9)
- Improved synthesis and purification of Alzheimer's Aβ 1–42 and analogs (1999) (9)
- Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer’s disease (2021) (8)
- Chemical synthesis of biologically active tat trans-activating protein of human immunodeficiency virus type 1 (1990) (8)
- Toxic Human IAPP Oligomers are Intracellular , and Vaccination to Induce Anti-toxic Oligomer Antibodies Does not Prevent Human IAPP Induced Beta-Cell Apoptosis in Human IAPP Transgenic Mice (2007) (7)
- In vitro study of the mechanism of intraneuronal β-amyloid aggregation in Alzheimer’s disease (2020) (7)
- An “epitomic” analysis of the specificity of conformation-dependent, anti-Aß amyloid monoclonal antibodies (2020) (6)
- Avoiding Collateral Damage in Alzheimer's Disease Treatment (2006) (5)
- O4-02-02 Common structure and mechanism of soluble amyloid oligomer pathogenesis in degenerative diseases (2004) (4)
- C1 activation by amyloid β fibrils. Evidence for a binding site for Aβ on the C1q globular regions (2000) (4)
- Antibodies Against b-Amyloid Reduce Ab Oligomers, Glycogen Synthase Kinase-3b Activation and s Phosphorylation In Vivo and In Vitro (2006) (3)
- Structural Diversity of Amyloid Oligomers (2010) (3)
- Synthesis of Alzheimer's (1–42) Aβ-amyloid peptide with preformed Fmoc-aminoacyl fluorides (1997) (2)
- When Sperm Meets Egg (1991) (2)
- Identification of amyloid antibodies for Alzheimer disease – immunotherapy (2020) (2)
- Aβ Structure and Aggregation (2007) (2)
- Biomedicine. Avoiding collateral damage in Alzheimer's disease treatment. (2006) (1)
- Abstract 16499: Preamyloid Oligomers are Present in Human Atrium and Are Associated With Post-Operative Atrial Fibrillation (2011) (1)
- Conformation-dependent anti-Aβ monoclonal antibody signatures of disease status and severity in urine of women with preeclampsia. (2022) (1)
- VITELLINE LAYER OF SEA URCHIN EGGS (1977) (1)
- P1-172 Annular protofibrils, formation, stability and toxicity: new insights into the pore-like mechanism for amyloid toxicity (2004) (1)
- Amyloid β Immunotherapy (2017) (1)
- Multiple Effects of Soluble Amyloid Peptide Oligomers on Human Potassium Channels (2007) (1)
- Abstract 13925: Reactive ?-Ketoaldehyde Products of Lipid Peroxidation Promote Protein Misfolding and Preamyloid Oligomer Formation in Experimental Atrial Fibrillation (2013) (1)
- 43 – AN ENDOGENOUS BACTERIAL PROTEASE SPECIFICALLY CLEAVES A FUSION PROTEIN JUNCTION CONSISTING OF CONSECUTIVE BASIC AMINO ACIDS TO GENERATE A BIOLOGICALLY-ACTIVE EUKARYOTIC ADHESIVE PROTEIN, BINDIN1 (1989) (1)
- Species specific gamete adhesion in sea urchins a quantitative assay for agglutination of eggs by bindin from sperm (1978) (1)
- Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques (2014) (1)
- Subtractive analysis of S. franciscanus and S. purpuratus ovary mRNA: what kinds of genes determine species-specificity? (1999) (1)
- g-Secretase Cleavage Is Distinct from Endoplasmic Reticulum Degradation of the Transmembrane Domain of the Amyloid Precursor Protein * (1998) (1)
- Specific rosette formation between fibroblasts and erythrocytes. (1981) (1)
- P2-356: Vaccination against generic prefibrillar amyloid oligomer antigens is effective in protecting cognitive function in Tg2576 mice (2008) (0)
- Amyloid Oligomers Alter The Conductance Of The Gramicidin Channel (2009) (0)
- Abstract 65: Desmin Preamyloid Oligomers in Experimental Heart Failure and Cultured Cardiac Myocytes (2015) (0)
- Modified desmin pre-amyloid oligomers are increased in experimental heart failure (2015) (0)
- Erratum: (Journal of General Physiology (2006) 128, 6 (637-647)) (2006) (0)
- New therapeutic modalities for Alzheimers disease (2017) (0)
- Improved synthesis and purification of Alzheimer's Aβ 1–42 and analogs (2004) (0)
- “Dementia Biomarker Discovery Through Differential Immune Response Analysis” (2020) (0)
- Detection of Amyloid-β Variants Using Electrochemically Grown Polymer Nanowires Modified with Conformation Dependant Antibodies (2010) (0)
- Fusion of Sperm and Egg Plasma Membranes During Fertilization (2019) (0)
- Nonhuman Amyloid Oligomer Epitope Reduces Alzheimer’s-Like Neuropathology in 3xTg-AD Transgenic Mice (2013) (0)
- Carbohydrate Specificity of Sea a Cell Surface Lectin Mediating Urchin Sperm Bindin: Sperm-Egg Adhesion (2003) (0)
- Cellular mechanisms of amylod accumulation & pathogenesis (2000) (0)
- O2-02-07: Neuronal activity promotes oligomer formation and accumulation at excitatory synapses (2008) (0)
- The Effects of Salts and Sugars on the Plasma Membrane Permeabilizing Activity of Polycationic Peptides Derived from Protoxins (2011) (0)
- S2-02-06: Immunological analysis of Aβ oligomer diversity using conformation-dependent antibodies (2008) (0)
- Fluorinated General Anesthetics Modulate Kv1.3 Potassium Channels and Interact With β-Amyloid Peptide: Is there a Link? (2010) (0)
- PROFESSIONAL, RESEARCH, AND TEACHING EXPERIENCE: (2012) (0)
- Immunogens and corresponding antibodies, which are specific for frequent high molecular weight aggregation intermediates of amyloid proteins from different sequence (2003) (0)
- An "epitomic" analysis of the specificity of conformation-dependent, anti-Aß amyloid monoclonal antibodies. (2020) (0)
- Effect of immunization with the oligomeric form of the Aβ peptide: Reduction of senile plaque area, decreased complement C3 deposition and synthesis, and decline in behavioral function in a murine model of Alzheimer's disease (2007) (0)
- X-Ray Structure of an Amyloid-Oligomer-Specific Monoclonal Antibody Fab (2010) (0)
- Do Not Seed Fibril Formation β Oligomerization of Monomeric Amyloid Fibrillar Oligomers Nucleate the Protein Structure and Folding (2010) (0)
- Vaccination with a non-human sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition in Tg2576 mice (2011) (0)
- ATOMIC STRUCTURES OF A SINGLE CHAIN ANTIBODY THAT BINDS AND INHIBITS SEEDING BY TAU OLIGOMERS (2019) (0)
- Differentially Modulated by C1q -Peptide in Microglia Is b Amyloid Antibody-Mediated Phagocytosis of the (2001) (0)
- P4-417 The phenolic antioxidant compound curcumin (CURC), and one of its metabolite tetrahydrocurcumin (THC) prevent Aβ oligomer formation, de-aggregate previously formed oligomers and are neuroprotective against oligomer toxicity (2004) (0)
- Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice (2012) (0)
- Isolation of VLs from Unfertilized Eggs (2003) (0)
- Dependence of Amyloid-β Oligomer (AβO) Interaction with Membranes on Preparation Method (2010) (0)
- ASSESSMENT OF POSSIBLE ASSOCIATION BETWEEN ANTIOXIDANT LEVELS AND APOE GENE POLYMORPHISM IN DEMENTED SAUDI POPULATION (2018) (0)
- Cellular Membranes as Targets in Amyloid Oligomer Disease Pathogenesis (2008) (0)
- P3-430 Conformation-dependent antibodies reveal the complexity of amyloid formation via seeding and cross-seeding (2006) (0)
- Amyloid Oligomers Increase the Lifetime and Single Channel Conductance of Gramicidin Channels (2010) (0)
- Decoding Darkness: The Search for the Genetic Causes of Alzheimer's Disease, by Rudolph E. Tanzi and Ann B. Parson, eds. (2001) (0)
- Desmin Preamyloid Oligomers in Experimental Heart Failure and CulturedCardiac Myocytes (2015) (0)
- The Oncogenic Jaagsiekte Sheep Retrovirus Cytoplasmic Tail Adopts a Unique Conformation on a Phosphocholine Surface (2012) (0)
- Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing beta-amyloid deposition and tau pathology in 3xTg-AD mice (2012) (0)
- Protective role of BDNF in amyloid-β-induced neurodegeneration of presynaptic axon arbors: in vivo imaging studies (2008) (0)
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