Charles G. Mullighan
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(Suggest an Edit or Addition)Charles G. Mullighan's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia (2007) (1753)
- The genetic basis of early T-cell precursor acute lymphoblastic leukaemia (2012) (1437)
- Somatic Histone H3 Alterations in Paediatric Diffuse Intrinsic Pontine Gliomas and Non-Brainstem Glioblastomas (2012) (1327)
- Acute Lymphoblastic Leukemia in Children. (2015) (1287)
- Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. (2009) (1048)
- BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros (2008) (1031)
- Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. (2014) (1029)
- Analysis of the Coding Genome of Diffuse Large B-Cell Lymphoma (2011) (929)
- Inactivating mutations of acetyltransferase genes in B-cell lymphoma (2010) (855)
- Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia (2008) (819)
- Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. (2009) (790)
- Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer (2013) (699)
- Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. (2012) (661)
- Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas (2013) (655)
- Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration. (2015) (644)
- Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation (2011) (643)
- The genomic landscape of hypodiploid acute lymphoblastic leukemia (2013) (585)
- Rearrangement of CRLF2 in B-progenitor– and Down syndrome–associated acute lymphoblastic leukemia (2009) (574)
- THE GENOMIC LANDSCAPE OF PEDIATRIC AND YOUNG ADULT T-LINEAGE ACUTE LYMPHOBLASTIC LEUKEMIA (2017) (569)
- JAK mutations in high-risk childhood acute lymphoblastic leukemia (2009) (569)
- CREBBP mutations in relapsed acute lymphoblastic leukaemia (2011) (562)
- Acute lymphoblastic leukaemia (2013) (515)
- Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia. (2010) (512)
- Pediatric acute lymphoblastic leukemia: where are we going and how do we get there? (2012) (498)
- CREST maps somatic structural variation in cancer genomes with base-pair resolution (2011) (487)
- A Novel Retinoblastoma Therapy from Genomic and Epigenetic Analyses (2011) (462)
- Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome. (2010) (390)
- The landscape of somatic mutations in Infant MLL rearranged acute lymphoblastic leukemias (2015) (371)
- Lin28 Enhances Tumorigenesis and is Associated With Advanced Human Malignancies (2009) (349)
- The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes (2014) (345)
- Genetic Basis of Acute Lymphoblastic Leukemia. (2017) (315)
- Contrasting roles for histone 3 lysine 27 demethylases in acute lymphoblastic leukemia (2014) (311)
- Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome (2017) (302)
- Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. (2011) (286)
- High Frequency and Poor Outcome of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Adults. (2017) (281)
- Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia (2015) (276)
- Mutations in CBL occur frequently in juvenile myelomonocytic leukemia. (2009) (275)
- PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia (2019) (274)
- Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia. (2012) (270)
- Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility (2000) (268)
- Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse (2013) (257)
- Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults. (2017) (253)
- A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia (2013) (253)
- Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome (2013) (250)
- International Consensus Classification of Myeloid Neoplasms and Acute Leukemia: Integrating Morphological, Clinical, and Genomic Data. (2022) (249)
- A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403. (2019) (239)
- Molecular genetics of B-precursor acute lymphoblastic leukemia. (2012) (231)
- Genomics in acute lymphoblastic leukaemia: insights and treatment implications (2015) (227)
- Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine. (2015) (226)
- Outcomes of children with BCR-ABL1–like acute lymphoblastic leukemia treated with risk-directed therapy based on the levels of minimal residual disease. (2014) (220)
- Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells (2010) (220)
- Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group. (2017) (214)
- Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia (2013) (214)
- Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. (2013) (212)
- Mannose-binding lectin gene polymorphisms are associated with major infection following allogeneic hemopoietic stem cell transplantation. (2002) (211)
- Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors. (2015) (210)
- Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells (2011) (210)
- Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting. (2016) (209)
- Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia. (2012) (207)
- A Children's Oncology Group and TARGET Initiative Exploring the Genetic Landscape of Wilms Tumor (2017) (201)
- Deregulation of DUX4 and ERG in acute lymphoblastic leukemia (2016) (197)
- The molecular genetic makeup of acute lymphoblastic leukemia. (2012) (195)
- Tyrosine kinase inhibitor therapy induces remission in a patient with refractory EBF1-PDGFRB-positive acute lymphoblastic leukemia. (2013) (195)
- The genomic landscape of core-binding factor acute myeloid leukemias (2016) (187)
- Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia. (2015) (185)
- Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia (2009) (182)
- Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia (2016) (181)
- Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study. (2012) (181)
- Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group. (2014) (181)
- Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. (2010) (180)
- The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy. (2012) (178)
- Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias (2007) (172)
- The genetic basis and cell of origin of mixed phenotype acute leukaemia (2018) (171)
- The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia. (2011) (167)
- Interleukins-1, -4, -6, -10, tumor necrosis factor, transforming growth factor-beta, FAS, and mannose-binding protein C gene polymorphisms in Australian women: Risk of preterm birth. (2004) (162)
- Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project. (2013) (159)
- Genome-wide profiling of genetic alterations in acute lymphoblastic leukemia: recent insights and future directions (2009) (149)
- Small molecule inhibition of CBP/catenin interactions eliminates drug resistant clones in acute lymphoblastic leukemia (2013) (148)
- Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia. (2010) (143)
- Germline Genetic Variation in ETV6 and Risk of Childhood Acute Lymphoblastic Leukemia: a Systematic Genetic Study (2015) (139)
- Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia. (2013) (133)
- Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia. (2015) (131)
- Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia (2015) (125)
- Pediatric acute lymphoblastic leukemia (2020) (125)
- Cyclin C is a haploinsufficient tumour suppressor (2014) (124)
- Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia. (2018) (121)
- Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma. (2019) (120)
- Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis (2017) (119)
- Improved CNS Control of Childhood Acute Lymphoblastic Leukemia Without Cranial Irradiation: St Jude Total Therapy Study 16. (2019) (116)
- NALP3 inflammasome up-regulation and CASP1 cleavage of the glucocorticoid receptor causes glucocorticoid resistance in leukemia cells (2015) (116)
- The genomic landscape of pediatric myelodysplastic syndromes (2016) (115)
- Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells (2011) (112)
- Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia. (2016) (108)
- Combined Targeting of JAK2 and Bcl-2/Bcl-xL to Cure Mutant JAK2-Driven Malignancies and Overcome Acquired Resistance to JAK2 Inhibitors (2013) (108)
- TP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children. (2018) (106)
- Favorable Outcomes for Older Adolescents and Young Adults (AYA) with Acute Lymphoblastic Leukemia (ALL): Early Results of U.S. Intergroup Trial C10403 (2014) (105)
- Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential (2014) (99)
- Failure of CDKN2A/B (INK4A/B-ARF)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL. (2008) (95)
- A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults. (2014) (95)
- IDH1 and IDH2 mutations in pediatric acute leukemia (2011) (93)
- Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia. (2010) (91)
- Human Gastrointestinal Neoplasia‐Associated Myofibroblasts Can Develop from Bone Marrow‐Derived Cells Following Allogeneic Stem Cell Transplantation (2009) (91)
- Non-HLA immunogenetic polymorphisms and the risk of complications after allogeneic hemopoietic stem-cell transplantation (2004) (90)
- Oncogenic role and therapeutic targeting of ABL-class and JAK-STAT activating kinase alterations in Ph-like ALL. (2017) (89)
- Cell of origin strongly influences genetic selection in a mouse model of T-ALL. (2011) (87)
- Genomic characterization of childhood acute lymphoblastic leukemia. (2013) (87)
- Emergence of Polyclonal FLT3 Tyrosine Kinase Domain Mutations during Sequential Therapy with Sorafenib and Sunitinib in FLT3-ITD–Positive Acute Myeloid Leukemia (2013) (87)
- Replicative potential of human natural killer cells (2009) (85)
- Clonal evolution mechanisms in NT5C2 mutant relapsed acute lymphoblastic leukemia (2017) (84)
- Genome-wide single-nucleotide polymorphism analysis in juvenile myelomonocytic leukemia identifies uniparental disomy surrounding the NF1 locus in cases associated with neurofibromatosis but not in cases with mutant RAS or PTPN11 (2007) (84)
- Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice. (2011) (83)
- RB1 gene inactivation by chromothripsis in human retinoblastoma (2014) (83)
- Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia (2013) (83)
- The genomic landscape of acute lymphoblastic leukemia in children and young adults. (2014) (81)
- Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia. (2020) (80)
- Genomic and outcome analyses of Ph-like ALL in NCI standard-risk patients: a report from the Children's Oncology Group. (2018) (79)
- Venetoclax and Navitoclax in Combination with Chemotherapy in Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma. (2021) (78)
- Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability (2018) (77)
- Outcome of children with hypodiploid ALL treated with risk-directed therapy based on MRD levels. (2015) (74)
- Genomic subtyping and therapeutic targeting of acute erythroleukemia (2019) (73)
- Global genomic characterization of acute lymphoblastic leukemia. (2009) (73)
- PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia. (2015) (72)
- CONSERTING: integrating copy-number analysis with structural-variation detection (2015) (71)
- Improving outcomes for high‐risk ALL: Translating new discoveries into clinical care (2011) (70)
- Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children (2015) (67)
- Genome-wide analysis links NFATC2 with asparaginase hypersensitivity. (2015) (67)
- Mutational landscape and patterns of clonal evolution in relapsed pediatric acute lymphoblastic leukemia. (2020) (67)
- Donor mannose-binding lectin deficiency increases the likelihood of clinically significant infection after liver transplantation. (2009) (67)
- Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors (2014) (66)
- TET2 mutations in myelodysplasia and myeloid malignancies (2009) (66)
- Genome sequencing of lymphoid malignancies. (2013) (65)
- Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group (2016) (65)
- Tissue Plasminogen Activator −7351C/T Enhancer Polymorphism Is a Risk Factor for Lacunar Stroke (2004) (64)
- Reference alignment of SNP microarray signals for copy number analysis of tumors (2009) (64)
- Philadelphia Chromosome–like Acute Lymphoblastic Leukemia (2017) (63)
- Notch/HES1-mediated PARP1 activation: a cell type-specific mechanism for tumor suppression. (2011) (61)
- Abstract 4869: Whole genome sequence analysis of MLL rearranged infant acute lymphoblastic leukemias reveals remarkably few somatic mutations: A Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project (2012) (61)
- Relapse fated latent diagnosis subclones in acute B lineage leukaemia are drug tolerant and possess distinct metabolic programs. (2020) (59)
- Development and Validation Of a Highly Sensitive and Specific Gene Expression Classifier To Prospectively Screen and Identify B-Precursor Acute Lymphoblastic Leukemia (ALL) Patients With a Philadelphia Chromosome-Like (“Ph-like” or “BCR-ABL1-Like”) Signature For Therapeutic Targeting and Clinical In (2013) (59)
- Integration of Next-Generation Sequencing to Treat Acute Lymphoblastic Leukemia with Targetable Lesions: The St. Jude Children’s Research Hospital Approach (2017) (58)
- Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia. (2009) (57)
- St. Jude Cloud—a Pediatric Cancer Genomic Data Sharing Ecosystem (2020) (57)
- Germline SAMD9 and SAMD9L mutations are associated with extensive genetic evolution and diverse hematologic outcomes. (2018) (57)
- Genomic profiling of B-progenitor acute lymphoblastic leukemia. (2011) (56)
- Rearrangement of CRLF 2 is associated with mutation of JAK kinases , alteration of IKZF 1 , Hispanic / Latino ethnicity , and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia * (2010) (55)
- Characterization of leukemias with ETV6-ABL1 fusion (2015) (55)
- Rearrangement of CRLF 2 in B-progenitor – and Down syndrome – associated acute lymphoblastic leukemia (2009) (54)
- MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours (2015) (53)
- Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses (2019) (53)
- Rare allelic forms of PRDM9 associated with childhood leukemogenesis (2013) (50)
- Genomic profiling of high-risk acute lymphoblastic leukemia (2010) (49)
- Advances in germline predisposition to acute leukaemias and myeloid neoplasms (2020) (49)
- Clinical efficacy of ruxolitinib and chemotherapy in a child with Philadelphia chromosome-like acute lymphoblastic leukemia with GOLGA5-JAK2 fusion and induction failure (2018) (48)
- Fas gene promoter polymorphisms in primary Sjögren’s syndrome (2003) (48)
- Lmo2 Induces Hematopoietic Stem Cell‐Like Features in T‐Cell Progenitor Cells Prior to Leukemia (2013) (48)
- PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia (2016) (48)
- Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma. (2018) (48)
- Advances in the Genetics of High-Risk Childhood B-Progenitor Acute Lymphoblastic Leukemia and Juvenile Myelomonocytic Leukemia: Implications for Therapy (2012) (48)
- LIM Domain Only-2 (LMO2) Induces T-Cell Leukemia by Two Distinct Pathways (2014) (47)
- New Strategies in Acute Lymphoblastic Leukemia: Translating Advances in Genomics into Clinical Practice (2010) (47)
- CICERO: a versatile method for detecting complex and diverse driver fusions using cancer RNA sequencing data (2020) (47)
- New directions in the genomics of allogeneic hematopoietic stem cell transplantation. (2007) (47)
- Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia (2021) (47)
- Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing (2021) (46)
- Bcl-2 Is a Therapeutic Target for Hypodiploid B-Lineage Acute Lymphoblastic Leukemia. (2019) (46)
- Mannose-binding lectin status is associated with risk of major infection following myeloablative sibling allogeneic hematopoietic stem cell transplantation. (2006) (46)
- Genomic analysis of acute leukemia (2009) (46)
- Synergism of FAK and tyrosine kinase inhibition in Ph+ B-ALL. (2016) (45)
- High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment (2017) (45)
- Evaluation of the In Vitro and In Vivo Efficacy of the JAK Inhibitor AZD1480 against JAK-Mutated Acute Lymphoblastic Leukemia (2014) (45)
- Polymorphisms in immunoregulatory genes and the risk of histologic chorioamnionitis in Caucasoid women: a case control study (2005) (43)
- Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk (2019) (43)
- Clinical impact of ABL1 kinase domain mutations and IKZF1 deletion in adults under age 60 with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL): molecular analysis of CALGB (Alliance) 10001 and 9665 (2016) (42)
- Shared acquired genomic changes in zebrafish and human T-ALL (2011) (41)
- TCF21 hypermethylation in genetically quiescent clear cell sarcoma of the kidney (2015) (41)
- TP53 Mutations in Hypodiploid Acute Lymphoblastic Leukemia. (2017) (41)
- CRLF2-Positive B-Cell Acute Lymphoblastic Leukemia in Adult Patients: A Single-Institution Experience (2017) (41)
- Tumor intrinsic and extrinsic determinants of response to blinatumomab in adults with B-ALL. (2020) (41)
- Novel susceptibility variants at the ERG locus for childhood acute lymphoblastic leukemia in Hispanics. (2019) (40)
- ETV6-NTRK3 induces aggressive acute lymphoblastic leukemia highly sensitive to selective TRK inhibition. (2018) (40)
- Ikaros: Exploiting and targeting the hematopoietic stem cell niche in B-progenitor acute lymphoblastic leukemia. (2017) (37)
- Highly sensitive MRD tests for ALL based on the IKZF1 Δ3–6 microdeletion (2011) (35)
- VPREB1 deletions occur independent of lambda light chain rearrangement in childhood acute lymphoblastic leukemia (2014) (35)
- Drugging DNA repair to target T-ALL cells (2018) (35)
- Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosome–like acute B-cell lymphoblastic leukemia (2018) (35)
- MLL Rearrangements Impact Outcome in HOXA-deregulated T-lineage Acute Lymphoblastic Leukemia: A Children's Oncology Group Study (2016) (35)
- Clinical significance of novel subtypes of acute lymphoblastic leukemia in the context of minimal residual disease-directed therapy. (2021) (35)
- Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data (2012) (33)
- Outcome modeling with CRLF 2 , IKZF 1 , JAK , and minimal residual disease in pediatric acute lymphoblastic leukemia : a Children ’ s Oncology Group Study (2012) (33)
- Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia (2020) (33)
- Genomic polymorphism and allogeneic hematopoietic transplantation outcome. (2006) (32)
- Ikaros and acute leukemia (2008) (32)
- ERG Deletions Define a Novel Subtype of B-Progenitor Acute Lymphoblastic Leukemia. (2007) (32)
- The Biology of B-Progenitor Acute Lymphoblastic Leukemia. (2019) (32)
- Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts (2014) (31)
- The genomic landscape of pediatric acute lymphoblastic leukemia (2022) (31)
- Discovery of Novel Recurrent Mutations in Childhood Early T-Cell Precursor Acute Lymphoblastic Leukemia by Whole Genome Sequencing - a Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project (2011) (31)
- Genome-wide association study of susceptibility loci for T-cell acute lymphoblastic leukemia in children. (2019) (31)
- Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome (2017) (31)
- Inherited genetic susceptibility of acute lymphoblastic leukemia in Down syndrome. (2019) (31)
- Targeting JAK 1 / 2 and mTOR in Murine Xenograft Models of Ph-like Acute Lymphoblastic Leukemia ( ALL ) (2012) (30)
- Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias. (2015) (30)
- Hyper-CVAD regimen in combination with ofatumumab as frontline therapy for adults with Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia: a single-arm, phase 2 trial. (2020) (29)
- Safety and Efficacy of Venetoclax in Combination with Navitoclax in Adult and Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (2019) (29)
- Enhancer hijacking drives oncogenic BCL11B expression in lineage ambiguous stem cell leukemia. (2021) (29)
- Defective K-Ras oncoproteins overcome impaired effector activation to initiate leukemia in vivo. (2013) (28)
- Molecular role of the PAX5‐ETV6 oncoprotein in promoting B‐cell acute lymphoblastic leukemia (2017) (28)
- YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway (2015) (28)
- Molecular Classification Improves Risk Assessment in Adult BCR-ABL1-negative B-ALL. (2021) (28)
- Variation in immune response genes and chronic Q fever. Concepts: preliminary test with post-Q fever fatigue syndrome (2003) (28)
- New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment (2018) (28)
- Mannose-binding Lectin and Infection Following Allogeneic Hemopoietic Stem Cell Transplantation (2004) (27)
- How new advances in genetic analysis are influencing the understanding and treatment of childhood acute leukemia (2011) (27)
- Clinical characteristics and outcomes of B-ALL with ZNF384 rearrangements: a retrospective analysis by the Ponte di Legno Childhood ALL Working Group (2021) (26)
- Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation (2021) (26)
- Genomic Assessment of Pediatric Acute Leukemia (2005) (25)
- Mechanistic insights and potential therapeutic targets for NUP98-rearranged hematologic malignancies. (2020) (25)
- Tumor-specific genetic lesions and their influence on therapy in pediatric acute lymphoblastic leukemia. (2006) (24)
- How advanced are we in targeting novel subtypes of ALL? (2019) (24)
- Molecular Basis of ETV6-Mediated Predisposition to Childhood Acute Lymphoblastic Leukemia. (2020) (24)
- Next Generation Transcriptomic Resequencing Identifies Novel Genetic Alterations in High-Risk (HR) Childhood Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group (COG) HR ALL TARGET Project. (2009) (24)
- Relapse of BCR-ABL1-like ALL mediated by the ABL1 kinase domain mutation T315I following initial response to dasatinib treatment (2014) (23)
- Modulation of Navitoclax Sensitivity by Dihydroartemisinin-Mediated MCL-1 Repression in BCR-ABL+ B-Lineage Acute Lymphoblastic Leukemia (2017) (23)
- The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms (2021) (23)
- Advances in the Genetics and Therapy of Acute Lymphoblastic Leukemia. (2016) (23)
- Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers. (2020) (22)
- Acquired isolated factor VII deficiency associated with severe bleeding and successful treatment with recombinant FVIIa (NovoSeven) (2004) (22)
- Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators (2021) (22)
- Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia. (2021) (22)
- Mixed‐phenotype acute leukemia: A cohort and consensus research strategy from the Children’s Oncology Group Acute Leukemia of Ambiguous Lineage Task Force (2020) (21)
- Aberrant STAT 5 and PI 3 K / mTOR pathway signaling occurs in human CRLF 2-rearranged B-precursor acute lymphoblastic leukemia (2012) (21)
- Advances in the Biology of Acute Lymphoblastic Leukemia-From Genomics to the Clinic. (2011) (21)
- OBI-3424, a Novel AKR1C3-Activated Prodrug, Exhibits Potent Efficacy against Preclinical Models of T-ALL (2019) (21)
- St. Jude Cloud-a Pediatric Cancer Genomic Data Sharing Ecosystem. (2021) (21)
- Biologic and Therapeutic Implications of Genomic Alterations in Acute Lymphoblastic Leukemia (2021) (20)
- Outcomes of paediatric patients with B-cell acute lymphocytic leukaemia with ABL-class fusion in the pre-tyrosine-kinase inhibitor era: a multicentre, retrospective, cohort study. (2021) (20)
- Mannose-binding lectin and maladies of the bowel and liver. (2006) (19)
- Cotargeting BCL-2 and MCL-1 in high-risk B-ALL. (2020) (19)
- Molecular markers in ALL: Clinical implications. (2020) (19)
- Epigenetic silencing of SOCS5 potentiates JAK‐STAT signaling and progression of T‐cell acute lymphoblastic leukemia (2019) (19)
- The role of TET2 in hematologic neoplasms. (2011) (19)
- Single nucleotide polymorphism microarray analysis of genetic alterations in cancer. (2011) (18)
- Germline deletion of ETV6 in familial acute lymphoblastic leukemia. (2019) (18)
- Pax5 Haploinsufficiency Cooperates with BCR-ABL1 to Induce Acute Lymphoblastic Leukemia (2008) (18)
- JAK2—a new player in acute lymphoblastic leukaemia (2008) (18)
- Clinical utility of whole-genome sequencing in precision oncology. (2021) (18)
- Association of Genetic Ancestry With the Molecular Subtypes and Prognosis of Childhood Acute Lymphoblastic Leukemia. (2022) (17)
- A genomic random interval model for statistical analysis of genomic lesion data (2013) (17)
- Modeling and targeting of erythroleukemia by hematopoietic genome editing. (2021) (16)
- Genomic Profiling for Clinical Decision Making in Myeloid Neoplasms and Acute Leukemia. (2022) (16)
- Lack of association between mannose-binding lectin gene polymorphisms and primary Sjögren's syndrome. (2000) (16)
- Novel ALK fusion in anaplastic large cell lymphoma involving EEF1G, a subunit of the eukaryotic elongation factor-1 complex (2017) (15)
- Genetic variation and the risk of acute lymphoblastic leukemia. (2010) (14)
- Cytochrome P450 1A2 is a target antigen in hepatitic graft-versus-host disease (2006) (14)
- Loss of p19Arf in a Rag1(-/-) B-cell precursor population initiates acute B-lymphoblastic leukemia. (2011) (14)
- Ruxolitinib or Dasatinib in Combination with Chemotherapy for Patients with Relapsed/Refractory Philadelphia (Ph)-like Acute Lymphoblastic Leukemia: A Phase I-II Trial (2017) (14)
- Mutant PRPS1: a new therapeutic target in relapsed acute lymphoblastic leukemia (2015) (13)
- Noncoding genetic variation in GATA3 increases acute lymphoblastic leukemia risk through local and global changes in chromatin conformation (2022) (13)
- Mutations of NOTCH1, FBXW7, and prognosis in T-lineage acute lymphoblastic leukemia (2009) (13)
- Deregulation of kinase signaling and lymphoid development in EBF1-PDGFRB ALL leukemogenesis (2017) (13)
- Whole Genome Sequence Analysis of 22 MLL Rearranged Infant Acute Lymphoblastic Leukemias Reveals Remarkably Few Somatic Mutations: A Report From the St Jude Children‘s Research Hospital - Washington University Pediatric Cancer Genome Project (2011) (13)
- Ikzf1 Haploinsufficiency Contributes to the Pathogenesis of BCR-ABL1 Positive Acute Lymphoblastic Leukemia. (2009) (13)
- Retroviral and Chemical Mutagenesis Identifies Pax5 as a Tumor Suppressor in B-Progenitor Acute Lymphoblastic Leukemia (2008) (13)
- LOHAS: loss‐of‐heterozygosity analysis suite (2011) (13)
- Genetic alterations targeting lymphoid development in acute lymphoblastic leukemia. (2011) (12)
- CREBBP Mutations In Relapsed Acute Lymphoblastic Leukemia (2010) (12)
- Pax 5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia (2014) (12)
- Absence of Biallelic TCR (cid:1) Deletion Predicts Early Treatment Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia (2010) (12)
- Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia (2022) (12)
- A BCR-ABL1-Like Gene Expression Profile Confers a Poor Prognosis In Patients with High-Risk Acute Lymphoblastic Leukemia (HR-ALL): A Report From Children's Oncology Group (COG) AALL0232 (2011) (12)
- Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia (2021) (11)
- Co-occurrence of CRLF2-rearranged and Ph+ acute lymphoblastic leukemia: a report of four patients (2017) (11)
- report from The Children's Oncology Group TARGET Project Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a (2012) (11)
- RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia. (2021) (11)
- Integrated Genomic and Mutational Profiling Of Adolescent and Young Adult ALL Identifies a High Frequency Of BCR-ABL1-Like ALL with Very Poor Outcome (2013) (11)
- Emergence of polyclonal FLT 3 tyrosine kinase domain mutations during sequential therapy with sorafenib and sunitinib in FLT 3-ITD-positive acute myeloid leukemia (2013) (11)
- Association of GATA3 polymorphisms with minimal residual disease and relapse risk in childhood acute lymphoblastic leukemia. (2020) (11)
- The age of the bone marrow microenvironment influences B-cell acute lymphoblastic leukemia progression via CXCR5-CXCL13. (2021) (10)
- Advances in the genomics of allogeneic haemopoietic stem cell transplantation (2004) (10)
- Philadelphia chromosome – like acute lymphoblastic leukemia in adults have frequent IGH-CRLF 2 and JAK 2 mutations , persistence of minimal residual disease and poor prognosis (2016) (10)
- Advances in the Genetics and Therapy of Acute Lymphoblastic Leukemia. (2016) (10)
- High Frequency and Poor Outcome of Ph-like Acute Lymphoblastic Leukemia in Adults (2015) (9)
- Leukemic presentation of ALK-positive anaplastic large cell lymphoma with a novel partner, poly(A) binding protein cytoplasmic 1 (PABPC1), responding to single-agent crizotinib (2019) (9)
- Inotuzumab Ozogamicin (Ino) May Overcome the Impact of Philadelphia Chromosome (Ph)-like Phenotype in Adult Patients (pts) with Relapsed/Refractory (R/R) Acute Lymphoblastic Leukemia (ALL) (2019) (9)
- Mannose-binding lectin deficiency does not increase the prevalence of Helicobacter pylori seropositivity (2007) (9)
- Germline RUNX1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia (2021) (9)
- LYMPHOID NEOPLASIA Genome-wide analysis links NFATC 2 with asparaginase hypersensitivity (2015) (9)
- Analytical Demands to Use Whole-Genome Sequencing in Precision Oncology. (2021) (9)
- Genetic characterization and therapeutic targeting of MYC‐rearranged T cell acute lymphoblastic leukaemia (2018) (8)
- Acute lymphoblastic leukemia displays a distinct highly methylated genome (2022) (8)
- Novel Chromosomal Rearrangements and Sequence Mutations in High-Risk Ph-Like Acute Lymphoblastic Leukemia (2011) (8)
- At three years, patients with acute lymphoblastic leukaemia are still at risk for relapse. Results of the international MRC UKALLXII/ECOG E2993 trial (2020) (8)
- Incidence of Germline Mutations in Cancer-Predisposition Genes in Children with Hematologic Malignancies: a Report from the Pediatric Cancer Genome Project (2014) (8)
- Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemia. (2022) (8)
- Genomic Characterization and Experimental Modeling Of BCR-ABL1 -Like Acute Lymphoblastic Leukemia (2013) (8)
- Mutations in the RAS Signaling, B-Cell Development, TP53/RB1, and JAK Signaling Pathways Are Common in High Risk B-Precursor Childhood Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group (COG) High-Risk (HR) ALL TARGET Project. (2009) (8)
- Therapeutic potential of ruxolitinib and ponatinib in patients with EPOR-rearranged Philadelphia chromosome-like acute lymphoblastic leukemia (2021) (8)
- Antileukemia Effects of Notch-Mediated Inhibition of Oncogenic PLK1 in B-Cell Acute Lymphoblastic Leukemia (2019) (8)
- Engineering naturally occurring CD7− T cells for the immunotherapy of hematological malignancies (2022) (8)
- International Consensus Classification of acute lymphoblastic leukemia/lymphoma (2022) (8)
- Constitutive Ras signaling and Ink4a/Arf inactivation cooperate during the development of B-ALL in mice. (2017) (8)
- RNAseqCNV: analysis of large-scale copy number variations from RNA-seq data (2022) (7)
- ShinyCNV: a Shiny/R application to view and annotate DNA copy number variations (2018) (7)
- Mutations in the B-Cell Transcription Factor PAX5 Found in B-Progenitor Acute Lymphoblastic Leukemia Impair Normal PAX5 Activity. (2006) (7)
- A Tumor Suppressor Enhancer of PTEN in T-cell development and leukemia. (2020) (7)
- Development of Potent and Selective Janus Kinase 2/3 Directing PG-PROTACs. (2022) (7)
- Activating killer‐cell immunoglobulin‐like receptor haplotype influences clinical outcome following HLA‐matched sibling haematopoietic stem cell transplantation (2018) (7)
- Clinical interpretation of whole-genome and whole-transcriptome sequencing for precision oncology. (2021) (7)
- Pharmacogenomics of intracellular methotrexate polyglutamates in patients' leukemia cells in vivo. (2020) (7)
- The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics (2020) (7)
- Genome-Wide Analysis of Genetic Alterations In Hypodiploid Acute Lymphoblastic Leukemia Identifies a High Frequency of Mutations Targeting the IKAROS Gene Family and Ras Signaling (2010) (6)
- Genome-wide association study of susceptibility loci for TCF3-PBX1 acute lymphoblastic leukemia in children. (2020) (6)
- Genome-Wide Analysis of Genetic Alterations in Chronic Myelogenous Leukemia. (2008) (6)
- CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk (2022) (6)
- Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma (2021) (6)
- Comparison Of Mutational Profiles Of Diagnosis and Relapsed Pediatric B-Acute Lymphoblastic Leukemia: A Report From The COG ALL Target Project (2013) (6)
- EARLY T-CELL PRECURSOR LEUKEMIA: A SUBTYPE OF VERY HIGH-RISK ACUTE LYMPHOBLASTIC LEUKEMIA IDENTIFIED IN TWO INDEPENDENT COHORTS (2010) (6)
- The PAX5‐JAK2 translocation acts as dual‐hit mutation that promotes aggressive B‐cell leukemia via nuclear STAT5 activation (2022) (6)
- Outcomes of Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia Based on Blast Genotype at Diagnosis: A Report from the Children's Oncology Group (2016) (6)
- Structure–function relationships explain CTCF zinc finger mutation phenotypes in cancer (2021) (5)
- ACUTE LYMPHOBLASTIC LEUKEMIA Rede fi ning ALL classi fi cation : toward detecting high-risk ALL and implementing precision medicine (2015) (5)
- Thymic Stromal Lymphopoietin Stimulation of Pediatric Acute Lymphoblastic Leukemias with CRLF2 Alterations Induces JAK/STAT and PI3K Phosphosignaling (2010) (5)
- Abstract 5173: Genetic profiling of central nervous system dissemination of B-acute lymphoblastic leukemia reveals clonal selection and therapeutic vulnerability (2018) (5)
- Non-coding germline GATA3 variants alter chromatin topology and contribute to pathogenesis of acute lymphoblastic leukemia (2020) (5)
- Acute Lymphoblastic Leukemia in Children with Down Syndrome: A Report From the Ponte Di Legno Study Group (2011) (5)
- Development of Mast Cell and Eosinophil Hyperplasia and HLH/MAS-Like Disease in NSG-SGM3 Mice Receiving Human CD34+ Hematopoietic Stem Cells or Patient-Derived Leukemia Xenografts (2020) (5)
- Erratum to Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors [Cancer Cell., 27, 286-297 (2015)] DOI: 10.1016/j.ccell.2015.02.008 (2015) (5)
- BCL-2, a Therapeutic Target for High Risk Hypodiploid B-Cell Acute Lymphoblastic Leukemia (2016) (5)
- Safety and Efficacy of the BCL Inhibitors Venetoclax and Navitoclax in Combination with Chemotherapy in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma: ALL‐131 (2018) (5)
- Targeting mTOR and JAK2 in Xenograft Models of CRLF2-Overexpressing Acute Lymphoblastic Leukemia (ALL) (2011) (5)
- The ASH Agenda for Hematology Research: a roadmap for advancing scientific discovery and cures for hematologic diseases. (2018) (5)
- The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment (2021) (5)
- NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia (2022) (5)
- Association of Combined Focal 22q11.22 Deletion and IKZF1 Alterations With Outcomes in Childhood Acute Lymphoblastic Leukemia. (2021) (5)
- Generation of Human Acute Lymphoblastic Leukemia Xenografts for Use in Oncology Drug Discovery (2015) (5)
- Venetoclax and Navitoclax in Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (2018) (5)
- The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia (2019) (5)
- The Genomic Landscape of Childhood T-Lineage Acute Lymphoblastic Leukemia (2015) (5)
- Integrated Transcriptomic and Genomic Sequencing Identifies Prognostic Constellations of Driver Mutations in Acute Myeloid Leukemia and Myelodysplastic Syndromes (2019) (4)
- ZNF384 fusion oncoproteins drive lineage aberrancy in acute leukemia. (2022) (4)
- CytofIn enables integrated analysis of public mass cytometry datasets using generalized anchors (2022) (4)
- High-Risk Subtype of Ph-like Acute Lymphoblastic Leukemia (ALL) in Adults: Dismal Outcomes of CRLF2+ ALL Patients Treated with Intensive Chemotherapy (2016) (4)
- Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia (2016) (4)
- Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia (2021) (4)
- Molecular genetics in children, adolescents and young adults with acute lymphoblastic leukemia and acute myeloid leukemia (2012) (4)
- Cytogenetics and Molecular Genetics (2017) (4)
- Genomic Determinants of Response to Blinatumomab in Relapsed/Refractory (R/R) B-Cell Precursor Acute Lymphoblastic Leukemia in Adults (2018) (4)
- Vitamin D receptor gene polmorphism further evidence for an association with Crohn's disease (1998) (4)
- Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia with kinase fusions in Taiwan (2021) (4)
- Somatic mutations in CTCF zinc fingers produce cellular phenotypes explained by structure-function relationships (2021) (4)
- Pediatric Acute Myeloid Leukemia with Nucleophosmin Mutations Is Characterized by a Gene Expression Signature with Dysregulated HOX Gene Expression Distinct from MLL-Rearranged Leukemias. (2005) (4)
- The Frequency and Outcome of Ph-like ALL Associated Abnormalities in Childhood Acute Lymphoblastic Leukaemia Treated on MRC UKALL2003 (2016) (4)
- Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target. (2021) (4)
- Outcomes of Patients with CRLF2-Overexpressing Acute Lymphoblastic Leukemia without Down Syndrome: A Report from the Children's Oncology Group (2020) (4)
- Lack of Somatic Sequence Mutations In Protein Tyrosine Kinase Genes Other Than the JAK Kinase Family In High Risk B-Precursor Childhood Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group (COG) High-Risk (HR) ALL TARGET Project (2010) (4)
- High-Resolution SNP Array Profiling of Relapsed Acute Leukemia Identifies Genomic Abnormalities Distinct from Those Present at Diagnosis. (2007) (4)
- Mixed Lineage Leukemia Rearrangements (MLL-R) Are Determinants of High Risk Disease in Homeobox A (HOXA)-deregulated T-Lineage Acute Lymphoblastic Leukemia: A Children's Oncology Group Study (2015) (3)
- A Tumor Suppressor Enhancer of PTEN in T-cell Development and Leukemia. (2021) (3)
- The Genomic Landscape of Childhood and Adult Acute Erythroid Leukemia (2016) (3)
- Consolidation Therapy with Blinatumomab Improves Overall Survival in Newly Diagnosed Adult Patients with B-Lineage Acute Lymphoblastic Leukemia in Measurable Residual Disease Negative Remission: Results from the ECOG-ACRIN E1910 Randomized Phase III National Cooperative Clinical Trials Network Trial (2022) (3)
- Efficacy of ALL Therapy for WHO2016-Defined Mixed Phenotype Acute Leukemia: A Report from the Children's Oncology Group (2017) (3)
- High Prevalence of Relapse in Australian Children with Ph-like Acute Lymphoblastic Leukemia Despite Risk Adapted Treatment (2015) (3)
- Genetic Modeling and Therapeutic Targeting of ETV6-NTRK3 with Loxo-101in Acute Lymphoblastic Leukemia (2016) (3)
- Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. (2022) (3)
- Acute Leukemia Classification Using Transcriptional Profiles From Low-Cost Nanopore mRNA Sequencing (2022) (3)
- Functional Analysis of Kinase-Activating Fusions in Ph-like Acute Lymphoblastic Leukemia (2014) (3)
- Molecular Biology of Childhood Leukemia (2021) (3)
- Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response (2022) (3)
- Welcoming a new age for gene therapy in hematology. (2016) (3)
- Therapy of pediatric ALL: from Bowie to Obama. (2013) (3)
- Discovery of novel predisposing coding and noncoding variants in familial Hodgkin lymphoma. (2022) (3)
- Genome-Wide Profiling of High-Risk Pediatric Acute Lymphoblastic Leukemia (ALL): The ALL Pilot Project for the Therapeutically Applicable Research To Generate Effective Treatments (TARGET) Initiative. (2007) (3)
- Defining Functional Heterogeneity In Acute Lymphoblastic Leukemia (2013) (3)
- Germline Genetic Variation in IKZF1 and Predisposition to Childhood Acute Lymphoblastic Leukemia (2015) (3)
- mTOR Kinase Inhibitors Enhance Efficacy of TKIs in Preclinical Models of Ph-like B-ALL (2016) (3)
- Nature GeNetics ADVANCE ONLINE PUBLICATION (2013) (3)
- The Role of Dominant-Negative IKAROS Mutations In the Pathogenesis and Treatment Responsiveness of BCR-ABL1 positive Acute Lymphoblastic Leukemia (2010) (3)
- Enhanced Risk Stratification of 21,178 Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia (ALL) Incorporating White Blood Count (WBC), Age, and Minimal Residual Disease (MRD) at Day 8 and 29 As Continuous Variables: A Children's Oncology Group (COG) Report (2020) (3)
- The landscape of coding RNA editing events in pediatric cancer (2021) (3)
- Whole genome sequencing provides comprehensive genetic testing in childhood B-cell acute lymphoblastic leukaemia (2023) (3)
- Combined Targeting of JAK2 with a Type II JAK2 Inhibitor and mTOR with a TOR Kinase Inhibitor Constitutes Synthetic Activity in JAK2-Driven Ph-like Acute Lymphoblastic Leukemia (2015) (3)
- Use of Genomic Technologies to Identify Novel Genetic Abnormalities and Therapeutic Targets In Acute Lymphoblastic Leukemia. (2008) (2)
- Lmo2 Overexpression and Arf Loss Induce Myeloid Differentiation in Primitive Thymocytes (2011) (2)
- Redefining the biological basis of lineage-ambiguous leukemia through genomics: BCL11B deregulation in acute leukemias of ambiguous lineage (2021) (2)
- Abstract 4729: Frequency of actionable gene fusions in patients with Philadelphia chromosome-like (Ph-like) B-acute lymphoblastic leukemia (ALL): A retrospective study from the Children's Oncology Group (COG) (2015) (2)
- Immunophenotyping of Murine Precursor B-Cell Leukemia/Lymphoma: A Comparison of Immunohistochemistry and Flow Cytometry (2019) (2)
- Novel UHRF1-MYC Axis in Acute Lymphoblastic Leukemia (2022) (2)
- Genome-Wide Single Nucleotide Polymorphism Analysis in Juvenile Myelomonocytic Leukemia Uncovers Long-Range Uniparental Disomy Surrounding the NF1 Locus in Cases Associated with Type 1 Neurofibromatosis but Not in Cases with Mutant RAS or PTPN11 . (2006) (2)
- Increased baseline RASGRP1 signals Enhance Stem Cell Fitness during Native Hematopoiesis (2020) (2)
- IKZF1 and 22q11.22 Deletions and PDGFRA Gains Are Associated with Poor Outcome in Down Syndrome Acute Lymphoblastic Leukemia (2012) (2)
- T-lineage lymphoblastic lymphoma and leukemia-a MASSive problem. (2010) (2)
- Expression of TCF3-ZNF384 in Human Hematopoietic Cells Induces Lineage Disruption in Vitro and Acute Leukemia in Vivo (2018) (2)
- Prediction of Patients at Risk of CD19Neg Relapse Following CD19-Directed CAR T Cell Therapy in B Cell Precursor Acute Lymphoblastic Leukemia (2019) (2)
- Phase II Study of the Hyper-CVAD Regimen in Combination with Ofatumumab (HCVAD-O) As Frontline Therapy for Adult Patients (pts) with CD20-Positive B-Cell Acute Lymphoblastic Leukemia (B-ALL) (2019) (2)
- Ultra-High Resolution Analysis of Genomic Alterations in High-Risk Acute Lymphoblastic Leukemia. (2008) (2)
- From trees to the forest: genes to genomics. (2011) (2)
- Efficacy of Focal Adhesion Kinase Inhibition in Combination with Dasatinib in BCR-ABL1 Acute Lymphoblastic Leukemia (2015) (2)
- Targeting mTOR Signaling Is An Effective Treatment Strategy for IKAROS and JAK Kinase Mutated Acute Lymphoblastic Leukemia (2010) (2)
- Relationship of CRLF2 expression and outcome in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): A report from the Children's Oncology Group. (2011) (2)
- Aurora A kinase as a target for therapy in TCF3-HLF rearranged acute lymphoblastic leukemia (2021) (2)
- BMP2/SMAD pathway activation in JAK2/p53-mutant Megakaryocyte/Erythroid Progenitors Promotes Leukemic Transformation. (2022) (2)
- Enhancer Hijacking of BCL11B Defines a Subtype of Lineage Ambiguous Acute Leukemia (2020) (2)
- GATA3 rs3824662A allele is associated with CRLF2 rearranged B-cell acute lymphoblastic leukemia in adults and adolescents and young adults (AYAs) and is associated with poor prognosis. (2020) (2)
- Recurrent Mutations of the C-C Motif Chemokine Ligand 22 (CCL22) Define a Distinct Subgroup of Chronic Lymphoproliferative Disorder of NK Cells (CLPD-NK) (2020) (2)
- Epigenetic Modulation of CD48 By NPM-ALK Promotes Immune Evasion in ALK+ ALCL (2019) (2)
- Outcomes of Patients with Down Syndrome and CRLF2-Overexpressing Acute Lymphoblastic Leukemia (ALL): A Report from the Children's Oncology Group (COG) (2020) (2)
- GATA3 rs3824662A allele in B‐cell acute lymphoblastic leukemia in adults, adolescents and young adults: association with CRLF2 rearrangement and poor prognosis (2020) (2)
- Identifying Drug-Resistant Mutations in Ebf1-Pdgfrb Ph-like Acute Lymphoblastic Leukemia (2015) (2)
- Functional analysis of germline ETV6 variants associated with familial thrombocytopenia and acute lymphoblastic leukemia (2017) (1)
- Comprehensive Functional Characterization of Germline ETV6 Variants Associated with Inherited Predisposition to Acute Lymphoblastic Leukemia in Children (2016) (1)
- Abstract 4369: Rearrangements of the erythropoietin receptor are recurrent in Ph-like acute lymphoblastic leukemia and are sensitive to Jak2 inhibition (2015) (1)
- transplantation following myeloablative sibling allogeneic hematopoietic stem cell Mannose-binding lectin status is associated with risk of major infection (2013) (1)
- Prognostic mutation constellations in acute myeloid leukaemia and myelodysplastic syndrome (2021) (1)
- VpreB surrogate light chain expression in B-lineage ALL: a report from the Children’s Oncology Group (2021) (1)
- Genetic Analysis of B-Cell Acute Lymphoblastic Leukemia Dissemination to the Central Nervous System Identifies Clonal Selection and Therapeutic Vulnerability (2018) (1)
- Genome-Wide DNA Methylation Analysis Reveals Biological and Clinical Insights In Relapsed Childhood Acute Lymphoblastic Leukemia: A Report From The COG ALL Target Project (2013) (1)
- T-Cell Receptor Gene Deletions Are Associated with High Risk Features and Worse Outcome In Childhood Precursor B-Cell Acute Lymphoblastic Leukemia (ALL) (2010) (1)
- Abstract 4870: Integrated genomic analysis of hypodiploid acute lymphoblastic leukemia (2012) (1)
- Mannose-binding lectin and liver transplantation. (2005) (1)
- Cryptic Truncating Rearrangements of the Erythropoietin Receptor in Ph-like Acute Lymphoblastic Leukemia (2014) (1)
- High Resolution Genomic Profiling Using Single Nucleotide Polymorphism Microarrays Identifies Multiple Novel Genomic Lesions in Pediatric Acute Lymphoblastic Leukemia. (2006) (1)
- Genomic Landscape of Relapsed Acute Lymphoblastic Leukemia (2015) (1)
- Abstract PR02: Investigating the use of tyrosine kinase inhibitors in Ph-like ALL. (2015) (1)
- Genes Regulating B-Cell Development and Differentiation Are Mutated in 40% of Pediatric Acute Lymphoblastic Leukemia. (2006) (1)
- Relapse-Initiating Clones Preexisting at Diagnosis in B- Cell Acute Lymphoblastic Leukemia Help Predict Molecular Pathways of Relapse (2018) (1)
- NUP98-KDM5A Fusion Induces Hematopoietic Cell Proliferation and Alters Myelo-Erythropoietic Differentiation (2019) (1)
- Burkitt Lymphoma Genome Sequencing Project (BLGSP): Introduction (2016) (1)
- Integrative genomic analysis of B‐lymphoblastic lymphoma with intrachromosomal amplification of chromosome 21 (2020) (1)
- Expression of an Oncogenic ERG isoform Characterizes a Distinct Subtype of B-Progenitor Acute Lymphoblastic Leukemia (2015) (1)
- Genomic subtyping and therapeutic targeting of acute erythroleukemia (2019) (1)
- In vivo monitoring of JAK/STAT and PI3K/mTOR signal transduction inhibition in pediatric CRLF2-rearranged acute lymphoblastic leukemia (ALL). (2012) (1)
- Identification of Novel Recurring Mutations in Relapsed Acute Lymphoblastic Leukemia. (2009) (1)
- IGF1 Brings Growing Pains for T-ALL LSCs. (2018) (1)
- IKZF1 (Ikaros) Deletions Are a Hallmark of BCR-ABL1 Positive Acute Lymphoblastic Leukemia. (2007) (1)
- Focal 22q11.22 Loss Combined with IKZF1 Alterations Predict Very Poor Outcome in Childhood Acute Lymphoblastic Leukemia (2011) (1)
- Characterization of Causal Variants at the GATA3 Loci Associated with Susceptibility to Ph-like Acute Lymphoblastic Leukemia (2017) (1)
- Genomic- and Transcriptomic Profiling Of Acute Lymphoblastic Leukemia With Dicentric Chromosomes (2013) (1)
- Burkitt Lymphoma Genome Sequencing Project (BLGSP): Integrative Genomic and Transcriptomic Characterization of Burkitt Lymphoma (2017) (1)
- KEY GENETIC AND MOLECULAR ABERRATIONS IDENTIFIED IN BOTH ADULT AND EBV‐POSITIVE BURKITT LYMPHOMA PATIENTS (2021) (1)
- Characterization of PAX5‐driven Subtypes in B‐progenitor Acute Lymphoblastic Leukemia: ALL‐114 (2018) (1)
- Venetoclax and Navitoclax in Pediatric Patients with Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (2020) (1)
- Germline RUNX1 Variation and Predisposition to T-Cell Acute Lymphoblastic Leukemia in Children (2019) (1)
- pediatric B-precursor acute lymphoblastic leukemia residual disease improve risk classification and outcome prediction in Gene expression classifiers for relapse-free survival and minimal (2010) (1)
- Association of the GATA3 rs3824662A allele with clinical outcomes in adult patients with adult B-ALL. (2019) (1)
- AF10 Fusion Transcripts Are Identified By HOXA9/10 and MEIS1 Overexpression In T-ALL: A Report From Children’s Oncology Group AALL0434 (2013) (1)
- Evolving heterogeneity in acute lymphoblastic leukemia (2014) (1)
- T-ALL Cell of origin strongly influences genetic selection in a mouse model of (2013) (1)
- DONOR MANNOSE-BINDING LECTIN DEFICIENCY TRIPLES THE RISK OF POST-LIVER TRANSPLANTATION INFECTION.: 17 (2008) (1)
- Functional and Genomic Characterization of the Interaction between Acute Lymphoblastic Leukemia Cells and the Microenvironment Identifies Pathways for Therapeutic Intervention (2018) (1)
- Genome-Wide Analysis Reveals Frequent Inactivating Mutations of Acetyltransferase Genes In B-Cell Lymphoma (2010) (1)
- CICERO: a versatile method for detecting complex and diverse driver fusions using cancer RNA sequencing data (2020) (1)
- Multi-Omic Based Antigen Discovery for the Immunotherapy of Pediatric Acute T Cell Lymphoblastic Leukemia (2020) (1)
- Childhood Leukemias: Molecular genetics of acute lymphoblastic leukemia (2012) (1)
- Characterization of Novel Subtypes in B Progenitor Acute Lymphoblastic Leukemia (2018) (1)
- we get there? Pediatric acute lymphoblastic leukemia: where are we going and how do (2012) (1)
- Gene Expression Profiling in Down Syndrome Acute Lymphoblastic Leukemia Identifies Distinct Profiles Associated with CRLF2 Expression Status. (2009) (1)
- Abstract 222: Genome-wide association study of acute lymphoblastic leukemia in children with Down syndrome (2018) (1)
- Gene expression signature associated with in vitro dexamethasone resistance and post-induction minimal residual disease in pediatric T-cell acute lymphoblastic leukemia. (2019) (1)
- PHF6 mutations in T‐lineage acute lymphoblastic leukemia (2010) (1)
- High-Resolution Genome-Wide Profiling of DNA Copy Number Abnormalities and Gene Resequencing in Pediatric Acute Myeloid Leukemia (AML). (2007) (1)
- Genome-Wide Association Study Identifies a Novel Susceptibility Locus At 10p12.31-12.2 for Childhood Acute Lymphoblastic Leukemia in Ethinically Diverse Populations (2012) (1)
- CytofIn enables integrated analysis of public mass cytometry datasets using generalized anchors (2022) (1)
- Whole Exome Sequencing of Pediatric Acute Lymphoblastic Leukemia Patients Identify Mutations in 11 Pathways: A Report from the Children's Oncology Group (2016) (1)
- Significant In Vivo Sensitivity to Aurora Kinase Inhibition in TCF3-Hlf rearranged Acute Lymphoblastic Leukemia (2018) (1)
- Genomic Landscape of Acute Erythroid Leukemia (2016) (1)
- ALL-031: The Impact of Genetic Ancestry on the Biology and Prognosis of Childhood Acute Lymphoblastic Leukemia (2021) (1)
- Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data (2012) (1)
- Acute Leukemias in Children. (2016) (0)
- Abstract 4873: Comprehensive analysis of 160 whole-genome sequences reveals striking telomere alteration patterns in 9 pediatric cancers (2012) (0)
- LGG Nat Genet Supplemental data 2013 (2013) (0)
- Heme-Sensing Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics (2020) (0)
- Histone Acetyltransferases Are Critical Interacting Proteins in NUP98-Rearranged Acute Myeloid Leukemia (2022) (0)
- Clinical characteristics and outcomes of B-cell precursor ALL with MEF2D rearrangements: a retrospective study by the Ponte di Legno Childhood ALL Working Group (2022) (0)
- CLL-156: Novel CCL22 Mutations Drive Chronic Lymphoproliferative Disorder of NK Cells Through Biased GPCR Signaling (2021) (0)
- Clinical Implementation of a Testing Algorithm for the Diagnosis of Ph-like B-Cell Acute Lymphoblastic Leukemia (2016) (0)
- G3BP2-KIT drives leukemia amenable to kinase inhibition in Ph-like ALL (2022) (0)
- N-Myc Is Overexpressed In Both Murine and Human Early T-Cell Precursor Leukemia and Is Sufficient To Initiate this Leukemia In Multipotent Primitive Arf-/- thymocytes (2013) (0)
- An Oncogene-Regulated Epigenetic Switch in T Cell Acute Lymphoblastic Leukemia (2014) (0)
- Understanding the mechanism of TCF3-HLF fusion oncoprotein-driven leukemogenesis (2022) (0)
- Proximally Biased V(D)J Recombination and Evolution of Non-Productive Clones in B-Cell Precursor Acute Lymphocytic Leukemia with KMT2A::AFF1 Fusion Genes (2022) (0)
- Running head: EBF1-PDGFRB IN B-CELL LEUKEMOGENESIS (2017) (0)
- The genomic landscape of pediatric myelodysplastic syndromes (2017) (0)
- Inherited GATA3 genetic Variants Are Associated With Childhood BCR-ABL1-Like Acute Lymphoblastic Leukemia and Increased Risk Of Relapse (2013) (0)
- Integrated Genomic Analysis Identifies UBTF Tandem Duplications As a Subtype-Defining Lesion in Pediatric Acute Myeloid Leukemia (2021) (0)
- OP-JNCI200138 933..937 (2021) (0)
- GENOME SEQUENCING AND ITS IMPACT ON HEMATOLOGY Genome sequencing of lymphoid malignancies (2016) (0)
- Real-time sharing of comprehensive clinical genomics sequencing data in St. Jude Cloud. (2019) (0)
- lymphoblastic leukemia B-cell precursor population initiates acute-/-in a Rag 1 p 19 Arf Loss of (2011) (0)
- Molecular origin of childhood acute lymphoblastic leukemia (2016) (0)
- ALL-144: Oncogenic Deregulation of BCL11B in Lineage Ambiguous Leukemia (2021) (0)
- Novel Genetic Subgroups Inform on Shared Pathobiology within Adult and Pediatric Burkitt Lymphoma (2021) (0)
- Genome-Wide Profiling of DNA Copy Number Abnormalities and Loss-Of-Heterozygosity in Pediatric Acute Myeloid Leukemia Using High-Resolution Single Nucleotide Polymorphism Microarrays. (2006) (0)
- S102: COMPREHENSIVE GENOME CHARACTERIZATION REVEALS NEW SUBTYPES AND MECHANISMS OF ONCOGENE DEREGULATION IN CHILDHOOD T-ALL (2022) (0)
- Prevalence of RNA Editing Events Affecting Coding Regions in Pediatric Leukemia (2016) (0)
- Abstract 2487: CONSERTING: an accurate method for detecting focal and gross somatic copy number alterations in cancer genome by next generation sequencing (2012) (0)
- W1968 Human Gastric Cancer-Associated Fibroblast-Like Cells Are Derived from the Bone Marrow (2008) (0)
- A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1 (2022) (0)
- Targeting of JAK-STAT signaling pathway and BCL-2 family proteins in Ph-like acute lymphoblastic leukemia (2015) (0)
- Comprehensive Genomic and DNA Methylation Analysis in Twins with ETV6-RUNX1 Acute Lymphoblastic Leukemia (2008) (0)
- Genomic Profiling of Acute Lymphoblastic Leukemia: Insights Into Pathogenesis, Prognosis, and Therapeutic Targets. (2009) (0)
- KMT2A-rearranged leukemia: the shapeshifter. (2022) (0)
- Germline exome variation in children with acute lymphoblastic leukemia (ALL): Preliminary Findings (2015) (0)
- Integrated Genetic and Epigenetic Analysis of Childhood Acute Lymphoblastic Leukemia Reveals a Synergistic Role for Structural and Epigenetic Lesions In Determining Disease Phenotype (2010) (0)
- Biology and Clinical Relevance of Mannose-Binding Lectin (2005) (0)
- Antonija Kreso Response in Colorectal Cancer Variable Clonal Repopulation Dynamics Influence Chemotherapy (2013) (0)
- Characterisation of children and adolescents with acute lymphoblastic leukaemia who presented without peripheral blood blasts at diagnosis (2022) (0)
- Rearrangement of CRLF2 in B-Progenitor and Down Syndrome Associated Acute Lymphoblastic Leukemia. (2009) (0)
- PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia (2019) (0)
- Cancer Therapy : Clinical Emergence of Polyclonal FLT 3 Tyrosine Kinase Domain Mutations during Sequential Therapy with Sorafenib and Sunitinib in FLT 3-ITD – Positive Acute Myeloid Leukemia (2013) (0)
- PS940 COMBINATION BCL-2 INHIBITOR THERAPY WITH VENETOCLAX AND NAVITOCLAX IN PATIENTS WITH RELAPSED/REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA AND LYMPHOBLASTIC LYMPHOMA (2019) (0)
- Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia (2022) (0)
- Preclinical pharmacokinetic and pharmacodynamic evaluation of dasatinib and ponatinib for the treatment of T-cell acute lymphoblastic leukemia. (2023) (0)
- The Influence of the Age of the Bone Marrow Microenvironment on Leukaemia Progression (2019) (0)
- subtypes of T-cell acute lymphoblastic leukemia tumor suppressor is mutated across the major molecular BCL11B The (2013) (0)
- The role of phase separation by NUP98 fusion oncoproteins in leukemia (2022) (0)
- Targeted gene expression classifier identifies pediatric T-cell acute lymphoblastic leukemia (T-ALL) patients at high risk for end induction minimal residual disease positivity. (2021) (0)
- Interaction between Acute Lymphoblastic Leukemia Cells and Its Microenvironment (2017) (0)
- Abstract PR03: Delineating the roles of lysine 27 methylation-associated epigenetic modulators in T cell leukemia. (2015) (0)
- Comparison of Current and Enhanced Risk Stratification of 21,199 Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia Using Objective Risk Categorization Criteria: A Children's Oncology Group Report (2021) (0)
- PI3K and MEK Inhibition in Hypodiploid Acute Lymphoblastic Leukemia (2016) (0)
- COPY NUMBER VARIATION ANALYSIS IDENTIFIES DISTINCT GENOMIC FEATURES IN ADULT BURKITT LYMPHOMA (2021) (0)
- Abstract PO-156: The impact of genetic ancestry on the biology and prognosis of childhood acute lymphoblastic leukemia (2022) (0)
- Inhibition of Pre-BCR Signaling Mediates a Metabolic Switch in B-Cell Progenitor Acute Lymphoblastic Leukemia (2021) (0)
- Abstract CT146: Prognostic and therapeutic significance of leukemia subtypes in the context of risk-directed therapy based on minimal residual disease levels in pediatric acute lymphoblastic leukemia (2021) (0)
- Multiplex CRISPR/Cas9-Based Genome Editing of Mouse Hematopoietic Stem Cells Recapitulates Acute Erythroid Leukemia and Identifies Therapeutic Targets (2018) (0)
- Abstract IA23: The genomic landscape of acute lymphoblastic leukemia (2014) (0)
- Expression Profiling for MEIS1 and HOXA9/10 Identifies an Increased Incidence of MLL Rearrangements in T-ALL: A Children's Oncology Group Study. (2012) (0)
- Advances in germline predisposition to acute leukaemias and myeloid neoplasms (2020) (0)
- Haploinsufficiency of Ebf1 Collaborates with BCR-ABL1 to Decrease the Latency of Acute Lymphoblastic Leukemia. (2008) (0)
- Deletion of IKZF1 (Ikaros) Predicts Poor Outcome and Impaired Maturation in B-Progenitor Acute Lymphoblastic Leukemia (2008) (0)
- Abstract 1269: Role of ribosomal protein, Rpl22 in regulating leukemic transformation (2015) (0)
- CCR New Strategies New Strategies in Acute Lymphoblastic Leukemia : Translating Advances in Genomics into Clinical Practice (2011) (0)
- Single-Cell Pan-Cancer Analysis Reveals Treatment Resistance Stem/Progenitor-like Subpopulation in the High-Risk Pediatric Leukemia (2022) (0)
- Abstract 3083: The genetic landscape of Ph-like acute lymphoblastic leukemia (2014) (0)
- Evaluationof the InVitro and InVivo Ef fi cacyof the JAK Inhibitor AZD 1480 against JAK-Mutated Acute Lymphoblastic Leukemia (2015) (0)
- Acute Lymphoblastic Leukemia-Associated PAX5 Mutations Induce Aberrant B Cell Development (2010) (0)
- Elevated Enhancer-Oncogene Contacts and Higher Oncogene Expression Levels by Recurrent CTCF Inactivating Mutations in Acute T Cell Leukemia (2023) (0)
- Erratum to The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy [Immunityn 37, (November 16, 2012), 813-826] (2014) (0)
- New Discoveries in Biology and Molecular Markers (2017) (0)
- Ikaros Mediates Antigen Escape Following CD19 CAR T Cell Therapy in r/r B-ALL (2021) (0)
- Comprehensive Genome Characterization of Childhood T-ALL Links Oncogene Activation Mechanism and Subtypes to Prognosis (2022) (0)
- Genomic Discoveries in Pediatric Mixed Phenotype Acute Leukemia Inform Therapeutic Approaches (2019) (0)
- IKZF1 plus Confers a Strong Adverse Prognostic Effect in Total Therapy Studies (XV/XVI) (2022) (0)
- Oral Abstract: ALL-031: The Impact of Genetic Ancestry on the Biology and Prognosis of Childhood Acute Lymphoblastic Leukemia (2021) (0)
- Abstract 997: Targeting the Jak/Stat signaling pathway is highly effective in xenograft models of early T cell precursor (ETP) acute lymphoblastic leukemia (ALL) (2014) (0)
- DNA Methylation-Based Burkitt Lymphoma Epitypes Have Distinct Molecular and Clinical Features (2022) (0)
- Molecular Characterization of a Novel Subtype of Pediatric Acute Lymphoblastic Leukemia. (2005) (0)
- IL7r receptor mutants initiate leukemia from multipotent primitive thymocytes in a novel mouse model of ETP leukemia (2013) (0)
- Abstract A25: Evolving functional heterogeneity in B-acute lymphoblastic leukemia (2016) (0)
- Oncology Group Study disease in pediatric acute lymphoblastic leukemia: a Children's , and minimal residual (2012) (0)
- Abstract SY08-01: Large-scale screens for cancer genes in the mouse (2012) (0)
- Genetic Heterogeneity and Evolution in Lymphoid Malignancies (2018) (0)
- Leukemia Prone B-Precursor Population in a p19ARF-/-RAG1-/- Mouse Model. (2009) (0)
- 30: An integrated genetic-protein analysis of the TNF-family pathway predicts for GVHD (2007) (0)
- MANNOSE-BINDING LECTIN STATUS IS ASSOCIATED WITH RISK OF MAJOR INFECTION FOLLOWING MYELOABLATIVE SIBLING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION Short title: MBL status and infection following allo-HCT (2008) (0)
- The International Consensus Classification of Acute Leukemias of Ambiguous Lineage. (2023) (0)
- Uncovering the leukemogenic mechanism of non-canonical NUP98 fusion oncoproteins. (2023) (0)
- Risk Factors for Blood Product Usage Following Sibling Allogeneic Haemopoietic Stem Cell Transplantation (allo-HCT). (2007) (0)
- Recurrent MEF2D Fusions Define A New Subtype of Acute Lymphoblastic Leukemia Associated with Older Age at Diagnosis and Poor Outcome (2016) (0)
- Cross-Species Comparison of Acquired Genetic Changes In T Cell Malignancy. (2010) (0)
- lymphoblastic leukemia: a report from the Children's Oncology Group Key pathways are frequently mutated in high-risk childhood acute (2013) (0)
- Abstract PR01: Global chromatin profiling identifies NSD2 mutations in pediatric acute lymphoblastic leukemia (2013) (0)
- 47-OR: The effect of KIR haplotype on clinical outcome following HLA-matched sibling haemopoietic stem cell transplantation (2009) (0)
- Abstract IA12: Modeling and targeting CREBBP mutations in relapsed acute lymphoblastic leukemia (2018) (0)
- pediatric B-progenitor acute lymphoblastic leukemia , Hispanic / Latino ethnicity , and a poor outcome in IKZF 1 alteration of kinases , JAK is associated with mutation of CRLF 2 Rearrangement of (2010) (0)
- Mullighan Genome sequencing of lymphoid malignancies (2013) (0)
- Identification of Cell Populations Associated with CD19Neg Relapse Following CAR T Cell Therapy in Acute Lymphoblastic Leukemia (2021) (0)
- Abstract SY25-04: Sequencing the genome of acute lymphoblastic leukemia (2012) (0)
- The Impact of Genetic Ancestry on the Biology and Prognosis of Childhood Acute Lymphoblastic Leukemia (2021) (0)
- Abstract 2118: Non-coding germline GATA3 variants alter chromatin topology and contribute to pathogenesis of acute lymphoblastic leukemia (2021) (0)
- Abstract 2063:SAMD9/SAMD9Lmutations in familial monosomy 7 (2018) (0)
- following allogeneic hemopoietic stem cell transplantation Mannose-binding lectin gene polymorphisms are associated with major (2002) (0)
- Characterization of new cryptic rearrangements of the erythropoietin receptor in Ph-like acute lymphoblastic leukemia (2015) (0)
- Evaluation of the In Vitro and In Vivo Ef fi cacy of the JAK Inhibitor AZD1480 against JAK-Mutated Acute Lymphoblastic Leukemia (2015) (0)
- Abstract 4755: Genome wide analysis of hypodiploid acute lymphoblastic leukemia identifies a high frequency of mutations targeting the IKAROS gene family and Ras signaling (2011) (0)
- AML-283 The Genetic Landscape of NUP98-Rearranged Pediatric Leukemia. (2022) (0)
- Human Models of NUP98-Rearranged Leukemia Reveal Fusion-Specific Molecular Mechanisms (2022) (0)
- Abstract 2930: Global chromatin profiling reveals NSD2 mutation in pediatric ALL (2014) (0)
- stjude/CICERO reference files (GRCh37-lite) (2020) (0)
- AML-117: The Genetic Landscape of Relapsed Pediatric Acute Myeloid Leukemia (2021) (0)
- Definition of Cytochrome P450 1A2 as a Target Autoantigen in the Hepatitic Variant of Hepatic Chronic Graft-Versus-Host Disease. (2005) (0)
- Establishing Immunocompetent Leukemia Models to Investigate the Impact of CAR T Cells on the Immune Microenvironment and Bone Marrow Niche (2022) (0)
- Abstract 6569: ClinGen Somatic and CIViC collaborate to comprehensively evaluate somatic variants in cancer (2023) (0)
- Abstract B24: Delineating the roles of lysine 27 methylation-associated epigenetic modulators in T cell leukemia. (2015) (0)
- Genomic landscape of Down syndrome-associated acute lymphoblastic leukemia. (2023) (0)
- The genetic basis and cell of origin of mixed phenotype acute leukaemia (2018) (0)
- Abstract 1188: Cell-of-origin determines genetic selection and defines T-cell acute lymphocytic leukemia sub-types in mouse models (2010) (0)
- KIR Haplotype May Influence Clinical Outcome Following HLA-Matched Sibling Haemopoietic Stem Cell Transplantation (2010) (0)
- A Transcriptional Classifier Identifies Pediatric T-Cell Acute Lymphoblastic Leukemias at High Risk for End of Induction Minimal Residual Disease (2022) (0)
- Extended TNF Genotyping Identifies TNF -857T as a Risk Factor for Acute Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation. (2006) (0)
- 2029 - THE RELAPSED B-CELL ACUTE LYMPHOBLASTIC LEUKAEMIA IMMUNE MICROENVIRONMENT (2019) (0)
- CTCF zinc finger mutations produce cellular phenotypes explained by structure-function relationships (2021) (0)
- Abstract CT027: Exploration of association of leukemic molecular profile with efficacy in patients (pts) with relapsed/refractory acute lymphoblastic leukemia (ALL) treated with inotuzumab ozogamicin (InO) in the phase 3 INO-VATE trial (2022) (0)
- Abstract A07: Characterizing the specific oncogenic and tumor suppressor roles of H3K27me3 epigenetic modulators in T cell leukemia (2013) (0)
- Progenitor Sub-Populations in Treatment Resistant T-ALL (2022) (0)
- Abstract 642: Genomes for Kids: Comprehensive DNA and RNA sequencing defining the scope of actionable mutations in pediatric cancer (2021) (0)
- Abstract 332: Targeting BCL-2 in hypodiploid acute lymphoblastic leukemia (2014) (0)
- Epigenomic mapping in B-cell acute lymphoblastic leukemia identifies transcriptional regulators and noncoding variants promoting distinct chromatin architectures (2023) (0)
- Abstract IA02: Precision medicine in acute lymphoblastic leukemia (2016) (0)
- Integrated analysis of 179 validated somatic sequence mutations with genome-wide copy number alterations and gene expression profiles revealed a high frequency of recurrent somatic alterations in key signaling pathways including B cell development/differentiation (2011) (0)
- Nuclear corepressors NCOR1/NCOR2 regulate B cell development, maintain genomic integrity and prevent transformation. (2022) (0)
- Abstract B04: Investigating the use of tyrosine kinase inhibitors in Ph-like ALL. (2015) (0)
- Elevated Enhancer-Oncogene Contacts and Higher Oncogene Expression Levels By Recurrent CTCF inactivating Mutations in T Cell Acute Lymphoblastic Leukemia (2021) (0)
- Single-cell analysis of acute lymphoblastic and lineage ambiguous leukemia - approaches and molecular insights. (2022) (0)
- Abstract 5478: CICERO: An accurate method for detecting complex and diverse driver fusions using cancer transcriptome sequencing (RNA-seq) data (2020) (0)
- 5. Acute lymphoblastic leukaemia (2016) (0)
- acute lymphoblastic leukemia Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like (2012) (0)
- Best Practice & Research Clinical Haematology (2011) (0)
- Abstract LB-180: The genetic landscape of Wilms tumor (2016) (0)
- Molecular Pathways and Targets in B-Cell Progenitor Acute Lymphoblastic Leukemia (2022) (0)
- Best of ASH 1 (2019) (0)
- Linking Subclonal Genetic Diversity with Functional Heterogeneity Identifies Diagnosis Subclones Destined to Relapse (2016) (0)
- The Influence of Genetic Ancestry on Disease Biology in Pediatric T-Cell Acute Lymphoblastic Leukemia (2022) (0)
- AML-158 Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation. (2022) (0)
- Genetic Variation in NFATC2 Is Associated with a Higher Risk of Asparaginase Allergy (2014) (0)
- Cooperating Oncogenes and Their Targets in LMO2-Induced T-Cell Leukemia (2011) (0)
- Mannose‐binding lectin and gastric cancer (2007) (0)
- Outcomes of adult patients with relapsed/refractory CRLF2 rearranged B-cell acute lymphoblastic leukemia. (2023) (0)
- Donor-derived mannose-binding lectin deficiency increases the risk of infection after liver transplantation (2008) (0)
- Abstract B21: Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia (2016) (0)
- Combination BCL-2 Inhibitor Therapy with Venetoclax and Navitoclax in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (2019) (0)
- Identification of New Risk Loci and Regulatory Mechanisms Influencing Genetic Susceptibility to Acute Lymphoblastic Leukaemia (2019) (0)
- Abstract 1961: Ikzf1 haploinsufficiency contributes to the pathogenesis of BCR-ABL1 positive acute lymphoblastic leukemia (2010) (0)
- Abstract 998: Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukemia (B-ALL): A report from the children's oncology group (COG) - Target - St. Jude Pediatric Cancer Genome Project (2014) (0)
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What Schools Are Affiliated With Charles G. Mullighan?
Charles G. Mullighan is affiliated with the following schools:
