Charles Lawrence
American bioinformatician and mathematician
Charles Lawrence 's AcademicInfluence.com Rankings


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Mathematics Biology
Charles Lawrence 's Degrees
- PhD Bioinformatics Stanford University
Why Is Charles Lawrence Influential?
(Suggest an Edit or Addition)According to Wikipedia, Charles "Chip" Lawrence is an American bioinformatician and mathematician, who is the pioneer in developing novel statistical approaches to biological sequence analysis. After his PhD graduation, Lawrence became the assistant professor in Systems Engineering and Operations Research and Statistics, in Rensselaer Polytechnic Institute. In the same time period of time , Lawrence worked as the consultant to the Ministry of Maternal and Child Health in Dominican Republic. From 1975 to 1981, he worked in the New York State Department of Health as the Director of Operations Research and Statistics, in the Division of Epidemiology.
Charles Lawrence 's Published Works
Published Works
- Detecting subtle sequence signals: a Gibbs sampling strategy for multiple alignment. (1993) (2028)
- Comparative analyses of multi-species sequences from targeted genomic regions (2003) (666)
- An expectation maximization (EM) algorithm for the identification and characterization of common sites in unaligned biopolymer sequences (1990) (570)
- A statistical sampling algorithm for RNA secondary structure prediction. (2003) (542)
- Human-mouse genome comparisons to locate regulatory sites (2000) (517)
- Sfold web server for statistical folding and rational design of nucleic acids (2004) (493)
- Gibbs motif sampling: Detection of bacterial outer membrane protein repeats (1995) (452)
- An empirical energy function for threading protein sequence through the folding motif (1993) (396)
- Gibbs Recursive Sampler: finding transcription factor binding sites (2003) (357)
- RNA secondary structure prediction by centroids in a Boltzmann weighted ensemble. (2005) (346)
- Bayesian Models for Multiple Local Sequence Alignment and Gibbs Sampling Strategies (1995) (345)
- Phylogenetic footprinting of transcription factor binding sites in proteobacterial genomes. (2001) (279)
- Extracting protein alignment models from the sequence database. (1997) (276)
- Algorithms for the optimal identification of segment neighborhoods. (1989) (267)
- Bayesian inference on biopolymer models (1999) (182)
- Statistical prediction of single-stranded regions in RNA secondary structure and application to predicting effective antisense target sites and beyond. (2001) (164)
- Effect of target secondary structure on RNAi efficiency. (2007) (163)
- Extent and nature of contacts between protein molecules in crystal lattices and between subunits of protein oligomers (1997) (162)
- Quantitative analysis of ribosome binding sites in E.coli. (1994) (159)
- Functional classification of cNMP-binding proteins and nucleotide cyclases with implications for novel regulatory pathways in Mycobacterium tuberculosis. (2000) (144)
- Bayesian adaptive sequence alignment algorithms (1998) (136)
- Global profiling of Shewanella oneidensis MR-1: expression of hypothetical genes and improved functional annotations. (2005) (126)
- Genome-wide analysis of A-to-I RNA editing by single-molecule sequencing in Drosophila (2013) (126)
- Factors influencing the identification of transcription factor binding sites by cross-species comparison. (2002) (122)
- Decoding human regulatory circuits. (2004) (116)
- Identification of co-regulated genes through Bayesian clustering of predicted regulatory binding sites (2003) (109)
- Specific Real-Time PCR for Simultaneous Detection and Identification of Legionella pneumophila Serogroup 1 in Water and Clinical Samples (2010) (93)
- Bayesian Clustering with Variable and Transformation Selections (2003) (93)
- Detection of likely transmembrane β-strand regions in sequences of mitochondrial pore proteins using the Gibbs sampler (1996) (91)
- Centroid estimation in discrete high-dimensional spaces with applications in biology (2008) (89)
- Markovian structures in biological sequence alignments (1999) (88)
- Structure clustering features on the Sfold Web server (2005) (74)
- The Gibbs Centroid Sampler (2007) (73)
- Algorithms for the optimal identification of segment neighborhoods (1989) (60)
- Clustering of RNA secondary structures with application to messenger RNAs. (2006) (52)
- Identification of a novel class in the alpha/beta hydrolase fold superfamily: the N-myc differentiation-related proteins. (2002) (52)
- A Bayesian Statistical Algorithm for RNA Secondary Structure Prediction (1999) (50)
- Sequencing ultra-long DNA molecules with the Oxford Nanopore MinION (2015) (49)
- A phylogenetic Gibbs sampler that yields centroid solutions for cis-regulatory site prediction (2007) (48)
- BALSA: Bayesian algorithm for local sequence alignment. (2002) (47)
- A probabilistic Pliocene–Pleistocene stack of benthic δ18O using a profile hidden Markov model (2017) (45)
- The Celera Discovery SystemTM (2002) (44)
- Exact Calculation of Distributions on Integers, with Application to Sequence Alignment (2009) (40)
- Probabilistic sequence alignment of stratigraphic records (2014) (38)
- Motifs and structural fold of the cofactor binding site of human glutamate decarboxylase (1998) (37)
- PhyloScan: identification of transcription factor binding sites using cross-species evidence (2007) (36)
- Detecting non-allelic homologous recombination from high-throughput sequencing data (2015) (35)
- Change point method for detecting regime shifts in paleoclimatic time series: Application to δ18O time series of the Plio‐Pleistocene (2009) (32)
- Automated mapping of large-scale chromatin structure in ENCODE (2008) (31)
- Anatomy of a preferred target site for the bacterial insertion sequence IS903. (2001) (24)
- Bayesian Protein Family Classifier (1998) (23)
- Rhodopseudomonas palustris Regulons Detected by Cross-Species Analysis of Alphaproteobacterial Genomes (2005) (23)
- A Bayesian method for classification of images from electron micrographs. (2002) (22)
- RNAG: a new Gibbs sampler for predicting RNA secondary structure for unaligned sequences (2011) (22)
- Measuring Global Credibility with Application to Local Sequence Alignment (2008) (20)
- Contribution of the Histone H3 and H4 Amino Termini to Gcn4p- and Gcn5p-mediated Transcription in Yeast* (2006) (18)
- An Integrated Perspective on Phylogenetic Workflows. (2016) (14)
- Bayesian Adaptive Alignment and Inference (1997) (13)
- Using the Gibbs Motif Sampler for phylogenetic footprinting. (2007) (12)
- The Role of Uncertainty in Estimating Lead/Lag Relationships in Marine Sedimentary Archives: A Case Study From the Tropical Pacific (2017) (12)
- Mammalian Genomes Ease Location of Human DNA Functional Segments but Not Their Description (2004) (11)
- An application of nonlinear optimization in molecular biology (2002) (11)
- Statistical models for biological sequence motif discovery (2002) (11)
- The Bayesian Change Point and Variable Selection Algorithm: Application to the δ18O Proxy Record of the Plio-Pleistocene (2014) (9)
- Assessing the validity and reproducibility of genome-scale predictions (2013) (9)
- TIMEOR: a web-based tool to uncover temporal regulatory mechanisms from multi-omics data (2020) (8)
- Comparison of Late Neogene Uk′37 and TEX86 Paleotemperature Records From the Eastern Equatorial Pacific at Orbital Resolution (2020) (7)
- The Relative Inefficiency of Sequence Weights Approaches in Determining a Nucleotide Position Weight Matrix (2005) (7)
- Revising transcriptome assemblies with phylogenetic information. (2021) (7)
- A Gibbs sampler for the detection of subtle motifs in multiple sequences (1994) (6)
- Revising transcriptome assemblies with phylogenetic information in Agalma1.0 (2017) (6)
- Identification of the most significant amphipathic helix with application to HIV and MHV envelope proteins (1990) (5)
- Characterization and visualization of RNA secondary structure Boltzmann ensemble via information theory (2018) (4)
- Heteroscedastic Gaussian Process Regression on the Alkenone over Sea Surface Temperatures (2019) (3)
- Cooling Towers and Legionellosis: a Large Urban Area Experience (2002) (3)
- Database Search Based on Bayesian Alignment (1999) (3)
- On efficient calculations for Bayesian variable selection (2012) (3)
- Using controls to limit false discovery in the era of big data (2018) (2)
- Autoregressive Statistical Modeling of a Peru Margin Multi-proxy Holocene Record Shows Correlation Not Causation, Flickering Regimes and Persistence (2018) (2)
- The Celera Discovery System TM (2001) (1)
- Dual Proxy Gaussian Process Stack: Integrating Benthic δ18𝕆 and Radiocarbon Proxies for Inferring Ages on Ocean Sediment Cores (2019) (1)
- A Multiple Continuous Signal Alignment Algorithm with Gaussian Process Profiles and an Application to Paleoceanography (2019) (1)
- NexusPSO : A Novel Algorithm to Detect Transcription Factor Binding Sites (2018) (1)
- Characterization and visualization of RNA secondary structure Boltzmann ensemble via information theory (2018) (1)
- Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible (2017) (1)
- Incorporating Within-Host Diversity in Phylogenetic Analyses for Detecting Clusters of New HIV Diagnoses (2022) (1)
- The Relative Inefficiency of Sequence Weights in Determining a Nucleotide Consensus Distribution (0)
- Foundations of statistical methods for multiple sequence alignment and structure prediction (1995) (0)
- Mammalian Genomes Ease the Location of Human Transcription Factor Binding Sites but Do Not Ease Their Description (2004) (0)
- Development of Bioinformatic and Experimental Technologies for Identification of Prokaryotic Regulatory Networks (2008) (0)
- Incorporating the effects of age uncertainty derived from benthic d18O alignment into paleoceanographic data compilations (2016) (0)
- Probabilistic Stack of 180 Plio-Pleistocene Benthic δ 18 O Records Constructed Using Profile Hidden Markov Models (2015) (0)
- Bayesian computational approaches for gene regulation studies of bioethanol and biohydrogen production (2012) (0)
- Database search based on Bayesian alignment Jun Zhu, Roland L/ithy (1999) (0)
- Statistical inference in high dimensional spaces of genomics: an RNA structural example (2012) (0)
- A Gaussian process state-space model for atmospheric CO2 and sea surface temperature index reconstruction from boron isotope and planktonic δ18O proxies (2020) (0)
- On the Timing of Glacial Terminations in the Equatorial Pacific (2015) (0)
- Probabilistic stratigraphic alignment of Pleistocene d18O records (2011) (0)
- Title: TIMEOR: a web-based tool to uncover temporal regulatory mechanisms from multi-omics data (2020) (0)
- A Gaussian process state-space model for sea surface temperature reconstruction from the alkenone paleotemperature proxy (2022) (0)
- Bayesian Inference Gaussian Process Multiproxy Alignment of Continuous Signals (BIGMACS): Applications for Paleoceanography (2019) (0)
- Probabilistic Generative Models for the Statistical Inference of Unobserved Paleoceanographic Events: Application to Stratigraphic Alignment for Inference of Ages (2014) (0)
- Identification and characterization of transcription networks in environmentally significant species (2005) (0)
- Comparing Four Age Model Techniques using Nine Sediment Cores from the Iberian Margin (2017) (0)
- Detecting SubtleSequence Signals:.A Gibbs Sampling StrategyforMultiple Alignment (1993) (0)
- Comparing age model techniques for the last glacial cycle: A case study of ten Iberian Margin sediment cores (2022) (0)
- Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible (2017) (0)
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