Charles N. Serhan
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Why Is Charles N. Serhan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Charles Nicholas Serhan is the Simon Gelman Professor of Anaesthesia at Harvard Medical School and a Professor of Oral Medicine, Infection and Immunity at Harvard School of Dental Medicine. Serhan is the Director of the Center for Experimental Therapeutics and Reperfusion Injury at Brigham and Women's Hospital.
Charles N. Serhan's Published Works
Published Works
- Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators (2008) (2660)
- Resolution of inflammation: the beginning programs the end (2005) (2292)
- Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. (1987) (2118)
- Pro-resolving lipid mediators are leads for resolution physiology (2014) (2085)
- Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. (2002) (1488)
- Lipid mediator class switching during acute inflammation: signals in resolution (2001) (1332)
- Novel Functional Sets of Lipid-Derived Mediators with Antiinflammatory Actions Generated from Omega-3 Fatty Acids via Cyclooxygenase 2–Nonsteroidal Antiinflammatory Drugs and Transcellular Processing (2000) (1128)
- Resolvin E1 and protectin D1 activate inflammation-resolution programmes (2007) (1102)
- Resolution of in flammation: state of the art, definitions and terms (2006) (1059)
- TLR11 Activation of Dendritic Cells by a Protozoan Profilin-Like Protein (2005) (1033)
- Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways. (2007) (999)
- Novel Docosatrienes and 17S-Resolvins Generated from Docosahexaenoic Acid in Murine Brain, Human Blood, and Glial Cells (2003) (983)
- Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1 (2005) (895)
- A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. (2005) (827)
- Resolvins and protectins in inflammation resolution. (2011) (826)
- Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions (2009) (799)
- Novel Docosanoids Inhibit Brain Ischemia-Reperfusion-mediated Leukocyte Infiltration and Pro-inflammatory Gene Expression* (2003) (792)
- Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. (2004) (723)
- Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. (1995) (707)
- International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family (2009) (699)
- Resolvin D1 binds human phagocytes with evidence for proresolving receptors (2010) (664)
- Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators. (2018) (663)
- Increased dietary intake of ω-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis (2007) (656)
- Proresolving lipid mediators and mechanisms in the resolution of acute inflammation. (2014) (655)
- Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes. (1984) (653)
- Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis (2009) (632)
- Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis. (2005) (598)
- Resolvin E1 Selectively Interacts with Leukotriene B4 Receptor BLT1 and ChemR23 to Regulate Inflammation1 (2007) (584)
- Infection Regulates Pro-Resolving Mediators that Lower Antibiotic Requirements (2012) (551)
- Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions (2010) (534)
- The resolution of inflammation (2012) (529)
- Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections (2012) (515)
- Resolvin D1 and Its Aspirin-triggered 17R Epimer (2007) (496)
- The Lipoxin Receptor ALX: Potent Ligand-Specific and Stereoselective Actions in Vivo (2006) (470)
- Molecular Circuits of Resolution: Formation and Actions of Resolvins and Protectins1 (2005) (465)
- Anti-inflammatory and proresolving lipid mediators. (2008) (465)
- Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor (2002) (460)
- Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor (1994) (450)
- Aspirin-triggered 15-Epi-Lipoxin A4 (LXA4) and LXA4 Stable Analogues Are Potent Inhibitors of Acute Inflammation: Evidence for Anti-inflammatory Receptors (1997) (447)
- Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators. (2012) (435)
- The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution. (2015) (430)
- Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution. (2005) (426)
- Resolvin E1 Regulates Inflammation at the Cellular and Tissue Level and Restores Tissue Homeostasis In Vivo1 (2007) (419)
- Novel lipid mediators and resolution mechanisms in acute inflammation: to resolve or not? (2010) (419)
- RvE1 protects from local inflammation and osteoclastmediated bone destruction in periodontitis (2006) (412)
- Specialized pro-resolving lipid mediators in the inflammatory response: An update. (2010) (412)
- Lipid mediator networks in cell signaling: update and impact of cytokines 1 (1996) (410)
- Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators (2008) (404)
- Resolvin E1 regulates interleukin 23, interferon-γ and lipoxin A4 to promote the resolution of allergic airway inflammation (2008) (398)
- Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis. (2006) (398)
- Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain (2012) (395)
- A Synthetic Antagonist for the Peroxisome Proliferator-activated Receptor γ Inhibits Adipocyte Differentiation* (2000) (385)
- Reduced Inflammation and Tissue Damage in Transgenic Rabbits Overexpressing 15-Lipoxygenase and Endogenous Anti-inflammatory Lipid Mediators 1 (2003) (383)
- Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms (2017) (378)
- Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome. (2015) (375)
- Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue. (2014) (375)
- Lipid mediators in the resolution of inflammation. (2015) (370)
- Resolvins and protectins in the termination program of acute inflammation. (2007) (369)
- Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins. (2010) (365)
- Microglia in Pain: Detrimental and Protective Roles in Pathogenesis and Resolution of Pain (2018) (365)
- Anti-Inflammatory Actions of Neuroprotectin D1/Protectin D1 and Its Natural Stereoisomers: Assignments of Dihydroxy-Containing Docosatrienes1 (2006) (365)
- The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R (2002) (364)
- Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4 (2002) (362)
- Resolvins, specialized proresolving lipid mediators, and their potential roles in metabolic diseases. (2014) (360)
- Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression (2006) (358)
- Protectin D1 Is Generated in Asthma and Dampens Airway Inflammation and Hyperresponsiveness1 (2007) (340)
- Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils. (1995) (338)
- Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE2 and LXA4 in the induction of macrophage death (2008) (336)
- Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers (2004) (330)
- Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent (2006) (324)
- Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis. (2004) (319)
- Emerging roles of resolvins in the resolution of inflammation and pain (2011) (313)
- Lipoxin formation during human neutrophil-platelet interactions. Evidence for the transformation of leukotriene A4 by platelet 12-lipoxygenase in vitro. (1990) (301)
- Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction (1996) (298)
- Resolvin D Series and Protectin D1 Mitigate Acute Kidney Injury1 (2006) (296)
- International Union of Pharmacology XXXVII. Nomenclature for Leukotriene and Lipoxin Receptors (2003) (291)
- MicroRNAs in resolution of acute inflammation: identification of novel resolvin Dl‐miRNA circuits (2011) (290)
- Identification of resolvin D2 receptor mediating resolution of infections and organ protection (2015) (287)
- Lipoxin A4 Stable Analogs Are Potent Mimetics That Stimulate Human Monocytes and THP-1 Cells via a G-protein-linked Lipoxin A4 Receptor* (1997) (286)
- Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia (2002) (281)
- Regulation of inflammation in cancer by eicosanoids. (2011) (281)
- Molecular circuits of resolution: formation and actions of resolvins and protectins (2005) (281)
- Resolution phase lipid mediators of inflammation: agonists of resolution. (2013) (280)
- Lipoxin biosynthesis and its impact in inflammatory and vascular events. (1994) (276)
- Activation of Lipoxin a4 Receptors by Aspirin-Triggered Lipoxins and Select Peptides Evokes Ligand-Specific Responses in Inflammation (2000) (271)
- Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-κB and AP-1 activation, and IL-8 gene expression in human leukocytes (2002) (263)
- Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity (2002) (262)
- Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation. (2011) (262)
- Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial. (2004) (260)
- Lipoxins and novel aspirin-triggered 15-epi-lipoxins (ATL): a jungle of cell-cell interactions or a therapeutic opportunity? (1997) (255)
- Phosphatidate and oxidized fatty acids are calcium ionophores. Studies employing arsenazo III in liposomes. (1981) (254)
- Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX. (2005) (251)
- Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses (2016) (249)
- Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. (1996) (243)
- Rapid Appearance of Resolvin Precursors in Inflammatory Exudates: Novel Mechanisms in Resolution1 (2008) (242)
- Resolution of acute inflammation in the lung. (2014) (242)
- The Docosatriene Protectin D1 Is Produced by TH2 Skewing and Promotes Human T Cell Apoptosis via Lipid Raft Clustering* (2005) (237)
- Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion. (1999) (237)
- Resolvin E1 Receptor Activation Signals Phosphorylation and Phagocytosis* (2009) (237)
- Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues. (1998) (237)
- Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1 (2012) (237)
- Novel anti-inflammatory--pro-resolving mediators and their receptors. (2011) (236)
- The novel 13S,14S ‐epoxy‐maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype (2013) (236)
- Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers. (1993) (235)
- Resolution of inflammation is altered in Alzheimer's disease (2015) (235)
- Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950–Metabolites in Frozen Human Plasma[S] (2017) (232)
- Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production. (2005) (231)
- Novel eicosanoid and docosanoid mediators: resolvins, docosatrienes, and neuroprotectins (2005) (231)
- Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat (2012) (229)
- Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs. (2012) (228)
- Identification of a Human Enterocyte Lipoxin A4 Receptor That Is Regulated by Interleukin (IL)-13 and Interferon γ and Inhibits Tumor Necrosis Factor α–induced IL-8 Release (1998) (228)
- Saturated‐efferocytosis generates pro‐resolving CD11blow macrophages: Modulation by resolvins and glucocorticoids (2011) (226)
- Trihydroxytetraenes: a novel series of compounds formed from arachidonic acid in human leukocytes. (1984) (225)
- Resolvin E2: identification and anti-inflammatory actions: pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis. (2006) (224)
- Resolvin E1, an EPA-derived mediator in whole blood, selectively counterregulates leukocytes and platelets. (2008) (224)
- Leukotriene B4 and phosphatidic acid are calcium ionophores. Studies employing arsenazo III in liposomes. (1982) (222)
- Leukotriene B4 is a complete secretagogue in human neutrophils: a kinetic analysis. (1982) (219)
- Activation of protein kinase C by lipoxin A and other eicosanoids. Intracellular action of oxygenation products of arachidonic acid. (1986) (219)
- Lipoxin A(4) analogues inhibit leukocyte recruitment to Porphyromonas gingivalis: a role for cyclooxygenase-2 and lipoxins in periodontal disease. (2000) (218)
- Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors. (2017) (215)
- Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci: Receptor-Dependent Actions (2012) (214)
- Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution (2007) (214)
- Lipoxin (LX)A4 and Aspirin-triggered 15-epi-LXA4 Inhibit Tumor Necrosis Factor 1α–initiated Neutrophil Responses and Trafficking: Regulators of a Cytokine–Chemokine Axis (1999) (214)
- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors (2021) (212)
- Resolvins (2002) (211)
- Lipoxins and aspirin-triggered 15-epi-lipoxin biosynthesis: an update and role in anti-inflammation and pro-resolution. (2002) (209)
- Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins. (1993) (208)
- Resolvin D1 and Aspirin-Triggered Resolvin D1 Promote Resolution of Allergic Airways Responses (2012) (208)
- Parasite-induced Lipoxin A4 Is an Endogenous Regulator of IL-12 Production and Immunopathology in Toxoplasma gondii Infection (2002) (208)
- Resolvin D3 and aspirin-triggered resolvin D3 are potent immunoresolvents. (2013) (206)
- Angioplasty Triggers Intracoronary Leukotrienes and Lipoxin A4: Impact of Aspirin Therapy (1992) (200)
- Lipoxins and new lipid mediators in the resolution of inflammation. (2006) (200)
- Aspirin-Triggered Lipoxins (15-epi-LX) Are Generated by the Human Lung Adenocarcinoma Cell Line (A549)–Neutrophil Interactions and Are Potent Inhibitors of Cell Proliferation (1996) (199)
- 15-epi-lipoxin A4 inhibits myeloperoxidase signaling and enhances resolution of acute lung injury. (2009) (194)
- Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils (1990) (192)
- Resolvin D2 Is a Potent Endogenous Inhibitor for Transient Receptor Potential Subtype V1/A1, Inflammatory Pain, and Spinal Cord Synaptic Plasticity in Mice: Distinct Roles of Resolvin D1, D2, and E1 (2011) (191)
- Aspirin-triggered lipoxin and resolvin E1 modulate vascular smooth muscle phenotype and correlate with peripheral atherosclerosis. (2010) (191)
- Impaired Local Production of Proresolving Lipid Mediators in Obesity and 17-HDHA as a Potential Treatment for Obesity-Associated Inflammation (2013) (190)
- Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC-MS/MS. (2012) (189)
- Resolving TRPV1- and TNF-α-Mediated Spinal Cord Synaptic Plasticity and Inflammatory Pain with Neuroprotectin D1 (2011) (188)
- Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense (2003) (187)
- Role for Periodontitis in the Progression of Lipid Deposition in an Animal Model (2003) (183)
- Cutting Edge: Humanized Nano-Proresolving Medicines Mimic Inflammation-Resolution and Enhance Wound Healing (2011) (183)
- Novel omega -- 3-derived local mediators in anti-inflammation and resolution. (2005) (182)
- Resolvins suppress tumor growth and enhance cancer therapy (2018) (182)
- The opportunistic pathogen Pseudomonas aeruginosa carries a secretable arachidonate 15-lipoxygenase (2004) (181)
- A search for endogenous mechanisms of anti-inflammation uncovers novel chemical mediators: missing links to resolution (2004) (180)
- Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses. (2001) (179)
- Aspirin-Triggered Lipoxin A4 and B4 Analogs Block Extracellular Signal-Regulated Kinase-Dependent TNF-α Secretion from Human T Cells 1 (2003) (179)
- Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7 (2014) (178)
- Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections (2015) (178)
- New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration. (2017) (177)
- Novel lipid mediator regulators of endothelial cell proliferation and migration: aspirin-triggered-15R-lipoxin A(4) and lipoxin A(4). (2002) (177)
- A Novel Anti-Inflammatory and Pro-Resolving Role for Resolvin D1 in Acute Cigarette Smoke-Induced Lung Inflammation (2013) (177)
- The resolution of inflammation: the devil in the flask and in the details (2011) (177)
- Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics. (2000) (174)
- Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function. (2015) (173)
- Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity (2018) (171)
- Oxidoreductases in Lipoxin A4 Metabolic Inactivation (2000) (169)
- Lipoxins and aspirin-triggered lipoxin inhibit inflammatory pain processing (2007) (167)
- Pathogen-induced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs. (1998) (164)
- Discovery of specialized pro-resolving mediators marks the dawn of resolution physiology and pharmacology. (2017) (163)
- Anti-angiogenesis effect of the novel anti-inflammatory and pro-resolving lipid mediators. (2009) (161)
- Novel n-3 Immunoresolvents: Structures and Actions (2013) (158)
- Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways. (2001) (158)
- Resolvin E2 Formation and Impact in Inflammation Resolution (2012) (157)
- Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes. (2006) (157)
- New Lives Given by Cell Death: Macrophage Differentiation Following Their Encounter with Apoptotic Leukocytes during the Resolution of Inflammation (2012) (155)
- Selective incorporation of (15S)-hydroxyeicosatetraenoic acid in phosphatidylinositol of human neutrophils: agonist-induced deacylation and transformation of stored hydroxyeicosanoids. (1990) (155)
- Cutting Edge: Maresin-1 Engages Regulatory T Cells To Limit Type 2 Innate Lymphoid Cell Activation and Promote Resolution of Lung Inflammation (2015) (155)
- Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19? (2020) (154)
- Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease. (2015) (153)
- Systems approach to inflammation resolution: identification of novel anti‐inflammatory and pro‐resolving mediators (2009) (153)
- Lipoxin A. Stereochemistry and biosynthesis. (1986) (149)
- Unesterified docosahexaenoic acid is protective in neuroinflammation (2013) (149)
- Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition: Part 1 - Fields of Precision Nutrition (2016) (147)
- Metabolic Inactivation of Resolvin E1 and Stabilization of Its Anti-inflammatory Actions* (2006) (147)
- Identification of lipoxin A4 and its relationship to the sulfidopeptide leukotrienes C4, D4, and E4 in the bronchoalveolar lavage fluids obtained from patients with selected pulmonary diseases. (1990) (145)
- Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis (2016) (144)
- Vagus nerve controls resolution and pro-resolving mediators of inflammation (2014) (144)
- Specialized proresolving mediator targets for RvE1 and RvD1 in peripheral blood and mechanisms of resolution (2011) (144)
- Altered Fatty Acid Composition of Dopaminergic Neurons Expressing α-Synuclein and Human Brains with α-Synucleinopathies* (2003) (143)
- Novel proresolving aspirin-triggered DHA pathway. (2011) (142)
- International Union of Basic and Clinical Pharmacology. LXXXIV: Leukotriene Receptor Nomenclature, Distribution, and Pathophysiological Functions (2011) (140)
- Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis (2010) (140)
- Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective (2014) (139)
- Lipoxins and novel 15‐epi‐lipoxin analogs display potent anti‐inflammatory actions after oral administration (2004) (139)
- Lipoxin recognition sites. Specific binding of labeled lipoxin A4 with human neutrophils. (1992) (139)
- Leukotriene B4 and lipoxin A4 are regulatory signals for neural stem cell proliferation and differentiation (2006) (138)
- Impaired Phagocytosis in Localized Aggressive Periodontitis: Rescue by Resolvin E1 (2011) (138)
- Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo (1999) (137)
- Specialized pro-resolving mediator network: an update on production and actions. (2020) (136)
- Cyclooxygenase-2-Derived Prostaglandin E2 and Lipoxin A4 Accelerate Resolution of Allergic Edema in Angiostrongylus costaricensis-Infected Rats: Relationship with Concurrent Eosinophilia1 (2000) (135)
- Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes (2017) (134)
- Resolvin E1, an endogenous lipid mediator derived from eicosapentaenoic acid, prevents dextran sulfate sodium–induced colitis (2008) (133)
- Transcellular biosynthesis of lipoxin A4 during adhesion of platelets and neutrophils in experimental immune complex glomerulonephritis. (1995) (132)
- Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages (2014) (131)
- Simultaneous lipidomic analysis of three families of bioactive lipid mediators leukotrienes, resolvins, protectins and related hydroxy-fatty acids by liquid chromatography/electrospray ionisation tandem mass spectrometry. (2008) (131)
- Aspirin-Triggered Lipoxins Override the Apoptosis-Delaying Action of Serum Amyloid A in Human Neutrophils: A Novel Mechanism for Resolution of Inflammation1 (2007) (131)
- Pro-Resolving Lipid Mediators (SPMs) and Their Actions in Regulating miRNA in Novel Resolution Circuits in Inflammation (2012) (131)
- The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: novel oxygenase products from omega-3 polyunsaturated fatty acids. (2005) (131)
- Melanoma growth is reduced in fat-1 transgenic mice: Impact of omega-6/omega-3 essential fatty acids (2006) (129)
- Diversity of lipid mediators in human adipose tissue depots. (2013) (128)
- Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis (2016) (128)
- Lipoxin A4 receptor activation is distinct from that of the formyl peptide receptor in myeloid cells: inhibition of CD11/18 expression by lipoxin A4-lipoxin A4 receptor interaction. (1995) (127)
- Lipoxin A4 stable analogs inhibit leukocyte rolling and adherence in the rat mesenteric microvasculature: role of P-selectin. (1997) (127)
- Rescue and repair during photoreceptor cell renewal mediated by docosahexaenoic acid-derived neuroprotectin D1 (2010) (123)
- Anti-microinflammatory lipid signals generated from dietary N-3 fatty acids via cyclooxygenase-2 and transcellular processing: a novel mechanism for NSAID and N-3 PUFA therapeutic actions. (2000) (123)
- Controlling the resolution of acute inflammation: a new genus of dual anti-inflammatory and proresolving mediators. (2008) (123)
- Cutting Edge: Lipoxin (LX) A4 and Aspirin-Triggered 15-Epi-LXA4 Block Allergen-Induced Eosinophil Trafficking1 (2000) (123)
- Conjunctival Goblet Cell Secretion Stimulated by Leukotrienes Is Reduced by Resolvins D1 and E1 To Promote Resolution of Inflammation (2011) (123)
- Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions. (2019) (123)
- Plasticity of leukocytic exudates in resolving acute inflammation is regulated by MicroRNA and proresolving mediators. (2013) (121)
- Anti-inflammatory actions of lipoxin A(4) stable analogs are demonstrable in human whole blood: modulation of leukocyte adhesion molecules and inhibition of neutrophil-endothelial interactions. (1999) (119)
- Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution (2017) (119)
- Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection (2017) (118)
- D‐series resolvin attenuates vascular smooth muscle cell activation and neointimal hyperplasia following vascular injury (2013) (118)
- Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a ‘stop’ signaling switch for aspirin‐triggered lipoxin A4 (1999) (117)
- Specialized Proresolving Mediators Enhance Human B Cell Differentiation to Antibody-Secreting Cells (2012) (116)
- Plasma Metabolomics in Human Pulmonary Tuberculosis Disease: A Pilot Study (2014) (116)
- Lipoxin A4 and Aspirin-Triggered 15-epi-Lipoxin A4 Inhibit Human Neutrophil Migration: Comparisons Between Synthetic 15 Epimers in Chemotaxis and Transmigration with Microvessel Endothelial Cells and Epithelial Cells 1 (2003) (115)
- Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA. (1998) (112)
- Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism (2007) (111)
- A Molecular Defect in Intracellular Lipid Signaling in Human Neutrophils in Localized Aggressive Periodontal Tissue Damage1 (2004) (110)
- Lipoxin A4 metabolism by differentiated HL-60 cells and human monocytes: conversion to novel 15-oxo and dihydro products. (1993) (110)
- Peptido-leukotrienes are potent agonists of von Willebrand factor secretion and P-selectin surface expression in human umbilical vein endothelial cells. (1995) (109)
- Candida albicans Modulates Host Defense by Biosynthesizing the Pro-Resolving Mediator Resolvin E1 (2007) (109)
- Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson’s disease (2019) (109)
- Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke (2012) (109)
- Aging Delays Resolution of Acute Inflammation in Mice: Reprogramming the Host Response with Novel Nano-Proresolving Medicines (2014) (109)
- Anesthetics Impact the Resolution of Inflammation (2008) (108)
- Enduring prevention and transient reduction of postoperative pain by intrathecal resolvin D1 (2011) (108)
- Resolvin E1 and Chemokine-like Receptor 1 Mediate Bone Preservation (2013) (108)
- Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA (2012) (107)
- Metabolomics‐Lipidomics of Eicosanoids and Docosanoids Generated by Phagocytes (2011) (107)
- Cutting Edge: Nociceptin Stimulates Neutrophil Chemotaxis and Recruitment: Inhibition by Aspirin-Triggered-15-Epi-Lipoxin A41 (2001) (106)
- Novel endogenous small molecules as the checkpoint controllers in inflammation and resolution: entrée for resoleomics. (2004) (106)
- Novel Resolvin D2 Receptor Axis in Infectious Inflammation (2017) (103)
- Novel chemical mediators in the resolution of inflammation: resolvins and protectins. (2006) (103)
- Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling (2016) (102)
- Resolvin E1 Regulates Adenosine Diphosphate Activation of Human Platelets (2010) (102)
- Neuroprotectin D1/protectin D1 stereoselective and specific binding with human retinal pigment epithelial cells and neutrophils. (2010) (101)
- NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B4 Synthesis (2017) (101)
- Resolvin E1 Metabolome in Local Inactivation during Inflammation-Resolution1 (2008) (100)
- Resolvin D1, protectin D1, and related docosahexaenoic acid-derived products: Analysis via electrospray/low energy tandem mass spectrometry based on spectra and fragmentation mechanisms (2007) (100)
- Lipoxin B4 regulates human monocyte/neutrophil adherence and motility: design of stable lipoxin B4 analogs with increased biologic activity (1998) (99)
- Human Milk Proresolving Mediators Stimulate Resolution of Acute Inflammation (2015) (99)
- Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Unique Proresolving Mediator–Heme Oxygenase-1 Circuits (2013) (99)
- A novel rat lipoxin A4 receptor that is conserved in structure and function (2003) (97)
- Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection (2014) (97)
- Exogenous Pathogen and Plant 15-Lipoxygenase Initiate Endogenous Lipoxin A4 Biosynthesis (2004) (96)
- Docosahexaenoic acid metabolome in neural tumors: identification of cytotoxic intermediates (2010) (96)
- Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. (1999) (96)
- Lovastatin Decreases Acute Mucosal Inflammation Via 15-epi-Lipoxin A4 (2010) (96)
- Profiling in resolving inflammatory exudates identifies novel anti‐inflammatory and pro‐resolving mediators and signals for termination (2010) (95)
- Novel proresolving and tissue‐regenerative resolvin and protectin sulfido‐conjugated pathways (2015) (94)
- Lipoxins and Related Eicosanoids: Biosynthesis, Biological Properties, and Chemical Synthesis (1991) (94)
- Success of prostaglandin E2 in structure–function is a challenge for structure-based therapeutics (2003) (94)
- Pro-Resolving Mediators in Regulating and Conferring Macrophage Function (2017) (93)
- Identification and Profiling of Specialized Pro-Resolving Mediators in Human Tears by Lipid Mediator Metabolomics. (2017) (93)
- Lipoxins stimulate prostacyclin generation by human endothelial cells (1989) (92)
- The Specialized Proresolving Mediator 17-HDHA Enhances the Antibody-Mediated Immune Response against Influenza Virus: A New Class of Adjuvant? (2014) (92)
- Adhesion promotes transcellular leukotriene biosynthesis during neutrophil-glomerular endothelial cell interactions: inhibition by antibodies against CD18 and L-selectin. (1992) (92)
- Formation of lipoxin A by granulocytes from eosinophilic donors (1987) (92)
- Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins. (2001) (91)
- Action of novel eicosanoids lipoxin A and B on human natural killer cell cytotoxicity: effects on intracellular cAMP and target cell binding. (1985) (91)
- Neuroprotectin/protectin D1 protects against neuropathic pain in mice after nerve trauma (2013) (91)
- Fundamentals of Inflammation (2010) (90)
- Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation (2016) (90)
- Changes in phosphatidylinositol and phosphatidic acid in stimulated human neutrophils. Relationship to calcium mobilization, aggregation and superoxide radical generation. (1983) (90)
- Molecular and Cellular Basis of Inflammation (1999) (90)
- Lipoxin synthase activity of human platelet 12-lipoxygenase. (1993) (89)
- Identification and structure elucidation of the pro‐resolving mediators provides novel leads for resolution pharmacology (2018) (89)
- Altered fatty acid composition of dopaminergic neurons expressing alpha-synuclein and human brains with alpha-synucleinopathies. (2003) (88)
- Lipoxin A-induced inhibition of human natural killer cell cytotoxicity: studies on stereospecificity of inhibition and mode of action. (1987) (88)
- Aspirin-triggered proresolving mediators stimulate resolution in cancer (2019) (88)
- On the stereochemistry and biosynthesis of lipoxin B. (1986) (88)
- Biological activities of lipoxin A include lung strip contraction and dilation of arterioles in vivo. (1987) (87)
- Thromboxane A2 is a key regulator of pathogenesis during Trypanosoma cruzi infection (2007) (87)
- Systems approach with inflammatory exudates uncovers novel anti-inflammatory and pro-resolving mediators. (2008) (86)
- Lipoxin generation by permeabilized human platelets. (1992) (86)
- Induction of functional lipoxin A4 receptors in HL-60 cells. (1993) (85)
- New endogenous anti-inflammatory and proresolving lipid mediators: implications for rheumatic diseases (2007) (85)
- The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation. (2016) (83)
- Formation of leukotrienes and hydroxy acids by human neutrophils and platelets exposed to monosodium urate. (1984) (83)
- On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE. (1989) (83)
- Activation of human monocytes and the acute monocytic leukemia cell line (THP-1) by lipoxins involves unique signaling pathways for lipoxin A4 versus lipoxin B4: evidence for differential Ca2+ mobilization. (1996) (82)
- Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue (2016) (81)
- Remodeling of neutrophil phospholipids with 15(S)-hydroxyeicosatetraenoic acid inhibits leukotriene B4-induced neutrophil migration across endothelium. (1994) (81)
- Total Synthesis of the Lipid Mediator PD1n-3 DPA: Configurational Assignments and Anti-inflammatory and Pro-resolving Actions (2014) (80)
- Rainbow trout (Oncorhynchus mykiss) brain cells biosynthesize novel docosahexaenoic acid-derived resolvins and protectins-Mediator lipidomic analysis. (2005) (80)
- Neuroprotectin D 1 : A docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress (2004) (80)
- Decoding Functional Metabolomics with Docosahexaenoyl Ethanolamide (DHEA) Identifies Novel Bioactive Signals* (2011) (79)
- Human Periodontal Stem Cells Release Specialized Proresolving Mediators and Carry Immunomodulatory and Prohealing Properties Regulated by Lipoxins (2015) (77)
- Resolvin D1 and Aspirin-Triggered Resolvin D1 Regulate Histamine-stimulated Conjunctival Goblet Cell Secretion (2013) (77)
- Aspirin‐triggered lipoxin A4 and lipoxin A4 up‐regulate transcriptional corepressor NAB1 in human neutrophils (2001) (76)
- Microfluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions (2012) (74)
- Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages. (2015) (74)
- Macrophage Proresolving Mediators-the When and Where. (2016) (74)
- Splenic leukocytes define the resolution of inflammation in heart failure (2018) (74)
- Identification of inflammatory and proresolving lipid mediators in bone marrow and their lipidomic profiles with ovariectomy and omega‐3 intake (2008) (73)
- Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages (2016) (72)
- Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation (2015) (72)
- Carcinogenesis: Failure of resolution of inflammation? (2020) (71)
- The Protectin Family of Specialized Pro-resolving Mediators: Potent Immunoresolvents Enabling Innovative Approaches to Target Obesity and Diabetes (2019) (71)
- Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance (2016) (70)
- Aspirin Has A Gender-Dependent Impact on Antiinflammatory 15-Epi-Lipoxin A4 Formation: A Randomized Human Trial (2005) (69)
- Lipid-Derived Mediators in Endogenous Anti-Inflammation and Resolution: Lipoxins and Aspirin-Triggered 15-epi-Lipoxins (2002) (69)
- Resolution of inflammation: An organizing principle in biology and medicine. (2021) (68)
- LXA4, aspirin-triggered 15-epi-LXA4, and their analogs selectively downregulate PMN azurophilic degranulation. (1999) (68)
- Intravascular filarial parasites elaborate cyclooxygenase-derived eicosanoids (1990) (67)
- A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae (2015) (67)
- Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases. (2019) (66)
- Endogenous phospholipid metabolism in stimulated neutrophils differential activation by FMLP and PMA. (1982) (66)
- Mediator-lipidomics: databases and search algorithms for PUFA-derived mediators. (2005) (66)
- A Stable Aspirin-Triggered Lipoxin A4 Analog Blocks Phosphorylation of Leukocyte-Specific Protein 1 in Human Neutrophils1 (2004) (66)
- Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome (2019) (65)
- The Atlas of Inflammation Resolution (AIR) (2020) (65)
- COX-3 the enzyme and the concept: steps towards highly specialized pathways and precision therapeutics? (2003) (64)
- Signalling the fat controller (1996) (63)
- Distinct Analgesic Actions of DHA and DHA-Derived Specialized Pro-Resolving Mediators on Post-operative Pain After Bone Fracture in Mice (2018) (63)
- Design, synthesis and bioactions of novel stable mimetics of lipoxins and aspirin-triggered lipoxins. (2005) (63)
- Neutrophil Resolvin E1 Receptor Expression and Function in Type 2 Diabetes (2017) (62)
- Stretching Impacts Inflammation Resolution in Connective Tissue (2016) (62)
- Resolvin D1 Reduces Emphysema and Chronic Inflammation. (2015) (62)
- Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation (2016) (62)
- Lipoxin A4 and lipoxin B4 stimulate the release but not the oxygenation of arachidonic acid in human neutrophils: Dissociation between lipid remodeling and adhesion (1990) (62)
- Transcellular regulation of eicosanoid biosynthesis. (1999) (61)
- Microscale arrays for the profiling of start and stop signals coordinating human-neutrophil swarming (2017) (61)
- Resolvin D4 attenuates the severity of pathological thrombosis in mice. (2019) (61)
- Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes (2015) (60)
- Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions (2022) (60)
- A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS. (2018) (59)
- Specialized pro-resolving lipid mediators are differentially altered in peripheral blood of patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction (2019) (59)
- Actions of lipoxin A4 and related compounds in smooth muscle preparations and on the microcirculation in vivo. (1988) (59)
- Polyisoprenyl phosphates in intracellular signalling (1997) (59)
- Toll-like receptor 7 stimulates production of specialized pro-resolving lipid mediators and promotes resolution of airway inflammation (2013) (58)
- Resolvin E 1 and Protectin D 1 Activate Inflammation-Resolution Programs (2009) (57)
- Formation of endogenous "antiinflammatory" lipid mediators by transcellular biosynthesis. Lipoxins and aspirin-triggered lipoxins inhibit neutrophil recruitment and vascular permeability. (2000) (57)
- Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological validation (2018) (57)
- Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli–driven acute inflammation (2018) (57)
- Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent. (2015) (57)
- Resolvin D5 Inhibits Neuropathic and Inflammatory Pain in Male But Not Female Mice: Distinct Actions of D-Series Resolvins in Chemotherapy-Induced Peripheral Neuropathy (2019) (56)
- Antimicrobial Aspects of Inflammatory Resolution in the Mucosa: A Role for Proresolving Mediators (2011) (56)
- Lipoxins: Eicosanoids carrying intra-and intercellular messages (1991) (56)
- Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis. (2018) (55)
- Cytosolic phospholipase A(2) in hypoxic pulmonary vasoconstriction. (2002) (54)
- 15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 Induce NF-κB Regulators in Bacterial Pneumonia (2018) (53)
- International Union of Pharmacology XLIV. Nomenclature for the Oxoeicosanoid Receptor (2004) (53)
- Anti-inflammatory and pro-resolving properties of benzo-lipoxin A(4) analogs. (2009) (53)
- Chiral lipidomics of E-series resolvins: aspirin and the biosynthesis of novel mediators. (2011) (52)
- Effects of prostaglandin D2, lipoxins and leukotrienes on sleep and brain temperature of rats. (1994) (52)
- Cytosolic phospholipase A2 in hypoxic pulmonary vasoconstriction (2002) (52)
- Resolution of inflammation in asthma. (2012) (52)
- The resolvin D1 analogue controls maturation of dendritic cells and suppresses alloimmunity in corneal transplantation. (2014) (52)
- Design and synthesis of benzo-lipoxin A4 analogs with enhanced stability and potent anti-inflammatory properties. (2008) (51)
- 17(R)‐Resolvin D1 differentially regulates TLR4‐mediated responses of primary human macrophages to purified LPS and live E. coli (2011) (51)
- Expression of BPI (bactericidal/permeability-increasing protein) in human mucosal epithelia. (2003) (51)
- Lipoxin A4 activates ALX/FPR2 Receptor to Regulate Conjunctival Goblet Cell Secretion (2016) (51)
- Chemical Mediators of Inflammation and Resolution in Post-Operative Abdominal Aortic Aneurysm Patients (2012) (50)
- Resolvin D3 multi-level proresolving actions are host protective during infection. (2016) (50)
- The action of lipoxin-A on glomerular microcirculatory dynamics in the rat. (1987) (50)
- Lipoxin biosynthesis by trout macrophages involves the formation of epoxide intermediates. (1994) (50)
- The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide. (2015) (50)
- Contributions of the Three CYP1 Monooxygenases to Pro-Inflammatory and Inflammation-Resolution Lipid Mediator Pathways (2013) (49)
- Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators* (2016) (49)
- Mediator lipidomics: search algorithms for eicosanoids, resolvins, and protectins. (2007) (49)
- Expression of 5-lipoxygenase in pulmonary artery endothelial cells. (2002) (49)
- Biosynthesis of D-Series Resolvins in Skin Provides Insights into their Role in Tissue Repair. (2018) (49)
- Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3 (2016) (49)
- Potent Anti‐Inflammatory and Pro‐Resolving Effects of Anabasum in a Human Model of Self‐Resolving Acute Inflammation (2018) (49)
- Resolvin D1 protects periodontal ligament. (2013) (48)
- Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertension. (2016) (48)
- Lipoxin A4 modulates adaptive immunity by decreasing memory B‐cell responses via an ALX/FPR2‐dependent mechanism (2014) (48)
- Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A4. (1999) (48)
- The endogenous pro-resolving mediators lipoxin A4 and resolvin E1 preserve organ function in allograft rejection. (2011) (48)
- Lipoxins: a new series of eicosanoids (biosynthesis, stereochemistry, and biological activities). (1988) (47)
- The effects of lipoxin A and lipoxin B on functional responses of human granulocytes. (1987) (47)
- IMP and AMP deaminase in reperfusion injury down-regulates neutrophil recruitment. (2000) (47)
- Adipocytes promote ovarian cancer chemoresistance (2019) (47)
- Lipoxin generation by human megakaryocyte-induced 12-lipoxygenase. (1992) (46)
- Novel Pro-Resolving Lipid Mediators in Inflammation Are Leads for Resolution Physiology (2014) (46)
- Renal hemodynamic actions of lipoxins in rats: a comparative physiological study. (1992) (46)
- Leukotrienes stimulate neutrophil adhesion to mesangial cells: modulation with lipoxins. (1990) (46)
- Endogenous Receptor Agonists: Resolving Inflammation (2007) (46)
- Eicosanoids in leukocyte function. (1994) (45)
- Native and aspirin-triggered lipoxins control innate immunity by inducing proteasomal degradation of TRAF6 (2008) (45)
- Protective Actions of Aspirin-Triggered (17R) Resolvin D1 and Its Analogue, 17R-Hydroxy-19-Para-Fluorophenoxy-Resolvin D1 Methyl Ester, in C5a-Dependent IgG Immune Complex–Induced Inflammation and Lung Injury (2014) (45)
- A cluster of immunoresolvents links coagulation to innate host defense in human blood (2017) (45)
- Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration. (2018) (44)
- Ajulemic acid, a synthetic cannabinoid, increases formation of the endogenous proresolving and anti‐inflammatory eicosanoid, lipoxin A4 (2009) (44)
- Lipoxin A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor-alpha-initiated neutrophil responses and trafficking: novel regulators of a cytokine-chemokine axis relevant to periodontal diseases. (1999) (44)
- Targeting lipid mediators in cancer biology (2018) (44)
- Circulating hydroxy fatty acids in familial Mediterranean fever. (1985) (44)
- Total synthesis of the anti-inflammatory and pro-resolving lipid mediator MaR1n-3 DPA utilizing an sp(3) -sp(3) Negishi cross-coupling reaction. (2014) (44)
- Immune responsive resolvin D1 programs myocardial infarction‐induced cardiorenal syndrome in heart failure (2018) (43)
- Identification of dual cyclooxygenase-eicosanoid oxidoreductase inhibitors: NSAIDs that inhibit PG-LX reductase/LTB(4) dehydrogenase. (2001) (43)
- Cutting Edge: Parathyroid Hormone Facilitates Macrophage Efferocytosis in Bone Marrow via Proresolving Mediators Resolvin D1 and Resolvin D2 (2014) (42)
- Functional Metabolomics Reveals Novel Active Products in the DHA Metabolome (2012) (42)
- Resolution of sickle cell disease-associated inflammation and tissue damage with 17R-resolvin D1. (2019) (41)
- Neuroprotectin/protectin D1: endogenous biosynthesis and actions on diabetic macrophages in promoting wound healing and innervation impaired by diabetes. (2014) (41)
- Divergent cyclooxygenase responses to fatty acid structure and peroxide level in fish and mammalian prostaglandin H synthases (2006) (41)
- The novel lipid mediator PD1n-3 DPA: An overview of the structural elucidation, synthesis, biosynthesis and bioactions. (2017) (41)
- Aspirin-triggered 15-epi-lipoxin A4 and stable analogs on lipoxin A4 are potent inhibitors of acute inflammation. Receptors and pathways. (1999) (40)
- Phospholipid bilayers enhance the stability of leukotriene A4 and epoxytetraenes: stabilization of eicosanoids by liposomes. (1989) (40)
- Tonic inhibition of chemotaxis in human plasma (2008) (40)
- Lipid mediator informatics-lipidomics: Novel pathways in mapping resolution (2006) (40)
- Atherosclerosis, Periodontal Disease, and Treatment with Resolvins (2017) (39)
- Stereocontrolled total synthesis of neuroprotectin D1 / protectin D1 and its aspirin-triggered stereoisomer. (2012) (39)
- Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia. (2016) (39)
- Nutrigenetic Disruption of Inflammation-Resolution Homeostasis and Atherogenesis (2011) (39)
- Stereocontrolled total synthesis of the potent anti-inflammatory and pro-resolving lipid mediator resolvin D3 and its aspirin-triggered 17R-epimer. (2013) (39)
- The Scent of a Phagocyte (2000) (38)
- Novel mediators and mechanisms in the resolution of infectious inflammation: evidence for vagus regulation (2019) (37)
- Novel pathways and endogenous mediators in anti-inflammation and resolution. (2003) (37)
- Resolution metabolomes activated by hypoxic environment (2019) (37)
- NEUTROPHILS: RELEASE OF MEDIATORS OF INFLAMMATION WITH SPECIAL REFERENCE TO RHEUMATOID ARTHRITIS * (1982) (37)
- Lack of resolution sensor drives age-related cardiometabolic and cardiorenal defects and impedes inflammation-resolution in heart failure (2019) (37)
- Characterization of lipoxins by combined gas chromatography and electron-capture negative ion chemical ionization mass spectrometry: formation of lipoxin A4 by stimulated human whole blood. (1991) (37)
- Lipoxin a 4 Stable Analogs Are Potent Mimetics That Stimulate Human Monocytes and THP-1 Cells via a G-protein-linked Lipoxin a 4 Receptor (1997) (37)
- Dexamethasone, pro‐resolving lipid mediators and resolution of inflammation in COVID‐19 (2020) (36)
- Lipoxins: putative braking signals in host defense, inflammation and hypersensitivity (1996) (36)
- Synthesis and Anti-inflammatory and Pro-resolving Activities of 22-OH-PD1, a Monohydroxylated Metabolite of Protectin D1 (2014) (36)
- Mediator lipidomics. (2005) (34)
- Identification of proresolving and inflammatory lipid mediators in human psoriasis. (2018) (33)
- A synthetic eicosanoid LX‐mimetic unravels host‐donor interactions in allogeneic BMT‐induced GvHD to reveal an early protective role for host neutrophils (2005) (33)
- Lipoxin and Aspirin-Triggered 15-epi-Lipoxin Cellular Interactions Anti-Inflammatory Lipid Mediators (1999) (33)
- Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1. (2014) (33)
- Synthesis of the 16S,17S-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages. (2015) (33)
- Aspirin triggered-lipoxin A4 reduces the adhesion of human polymorphonuclear neutrophils to endothelial cells initiated by preeclamptic plasma. (2012) (33)
- Production of arachidonic acid lipoxygenase products during platelet-neutrophil interactions. (1984) (32)
- Evidence for a 5(6)‐epoxytetraene intermediate in the biosynthesis of lipoxins in human leukocytes (1986) (32)
- Cell-cell interaction in the transcellular biosynthesis of novel omega-3-derived lipid mediators. (2006) (32)
- New maresin conjugates in tissue regeneration pathway counters leukotriene D4–stimulated vascular responses (2018) (32)
- Characterization of human neutrophil and endothelial cell ligand-operated extracellular acidification rate by microphysiometry: impact of reoxygenation. (1998) (32)
- Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity. (2000) (31)
- Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution (2020) (31)
- Novel Antiinflammatory Targets for Asthma (2001) (31)
- Antiinflammatory potential of lipoxygenase-derived eicosanoids: a molecular switch at 5 and 15 positions? (1997) (31)
- Novel polyisoprenyl phosphates block phospholipase D and human neutrophil activation in vitro and murine peritoneal inflammation in vivo (2005) (31)
- Nomenclature of lipoxins and related compounds derived from arachidonic acid and eicosapentaenoic acid. (1987) (31)
- Endogenous Chemical Mediators in Anti-Inflammation and Pro-Resolution (2002) (30)
- Gene Expression of Proresolving Lipid Mediator Pathways Is Associated With Clinical Outcomes in Trauma Patients (2015) (30)
- Total synthesis of novel geometric isomers of lipoxin A4 and lipoxin B4 (1989) (30)
- Inhibition of human natural killer cell activity by (14R,15S)-14,15-dihydroxy-5Z,8Z,10E,12E- icosatetraenoic acid. (1984) (30)
- Lipoxin A4 Counter-regulates Histamine-stimulated Glycoconjugate Secretion in Conjunctival Goblet Cells (2016) (30)
- Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132 (2018) (30)
- Lipid Mediator Informatics and Proteomics in Inflammation-Resolution (2006) (30)
- A general method, employing arsenazo III in liposomes, for study of calcium ionophores: results with A23187 and prostaglandins. (1980) (30)
- ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance (2017) (29)
- Synthesis of 19,19,20,20,20-pentadeuteriolipoxin A4 methyl ester and 19,19,20,20,20-pentadeuterioarachidonic acid. Agents for use in the quantitative detection of naturally occurring eicosanoids (1989) (28)
- The Atlas of Inflammation-Resolution (AIR) (2020) (28)
- Cutting Edge: Human Vagus Produces Specialized Proresolving Mediators of Inflammation with Electrical Stimulation Reducing Proinflammatory Eicosanoids (2018) (28)
- PGBX, a prostagandin derivative, mimics the action of the calcium ionophore A23187 on human neutrophils. (1980) (28)
- Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways (2017) (28)
- Stereochemistry, total synthesis, and biological activity of 14,15-dihydroxy-5,8,10,12-eicosatetraenoic acid. (1984) (28)
- Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins (2016) (27)
- Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: emergence of the counterregulatory side. (2001) (27)
- Lipoxins and Aspirin-Triggered 15-epi-Lipoxins (2010) (27)
- Lipoxin biosynthesis and actions: role of the human platelet LX-synthase. (1995) (27)
- Impact of Aspirin Therapy (2005) (27)
- Molecular and Cellular Differences in Cardiac Repair of Male and Female Mice (2020) (26)
- Identification of a novel 7-cis-11-trans-lipoxin A4 generated by human neutrophils: total synthesis, spasmogenic activities and comparison with other geometric isomers of lipoxins A4 and B4. (1989) (26)
- Leukocyte adhesion promotes biosynthesis of lipoxygenase products by transcellular routes. (1994) (26)
- Aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogs inhibit neutrophil-mediated changes in vascular permeability. (1999) (26)
- Exploring new approaches to the treatment of asthma: potential roles for lipoxins and aspirin-triggered lipid mediators. (2003) (25)
- A New E-Series Resolvin: RvE4 Stereochemistry and Function in Efferocytosis of Inflammation-Resolution (2021) (25)
- Novel Endogenous Proresolving Molecules:Essential Fatty Acid-Derived and Gaseous Mediators in the Resolution of Inflammation. (2016) (24)
- Addition of aspirin to a fish oil-rich diet decreases inflammation and atherosclerosis in ApoE-null mice. (2016) (24)
- Identification of endogenous resolvin E1 and other lipid mediators derived from eicosapentaenoic acid via electrospray low-energy tandem mass spectrometry: spectra and fragmentation mechanisms. (2007) (24)
- Agonist-induced lipoxin A4 generation: Detection by a novel lipoxin A4-ELISA (1993) (24)
- Immunoresolvents signaling molecules at intersection between the brain and immune system (2018) (23)
- Carrier-mediated transport of lipoxin A4 in human neutrophils. (1994) (23)
- Lipoxin A4 decreases human memory B cell antibody production via an ALX/FPR2-dependent mechanism: A link between resolution signals and adaptive immunity (P5151) (2013) (23)
- Ca2+ mobilization with leukotriene A4 and epoxytetraenes in human neutrophils. (1990) (22)
- Potential vascular roles for lipoxins in the "stop programs" of host defense and inflammation. (1995) (22)
- Production of metabolic products of arachidonic acid during cell-cell interactions. (1984) (22)
- Frontline Science: Structural insights into Resolvin D4 actions and further metabolites via a new total organic synthesis and validation (2018) (22)
- Cell-Cell Interactions in the Release of Inflammatory Mediators (1991) (22)
- Metabololipidomic profiling of functional immunoresolvent clusters and eicosanoids in mammalian tissues. (2018) (21)
- Novel antiinflammatory targets for asthma. A role for PPARgamma? (2001) (21)
- A phospholipase A2 isoenzyme provokes lipoxin B formation from endogenous sources of arachidonic acid in porcine leukocytes. (1987) (21)
- Identification of Chemotype Agonists for Human Resolvin D1 Receptor DRV1 with Pro-Resolving Functions. (2019) (20)
- Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). (1999) (20)
- Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion. (1994) (20)
- Resolvin D1 Treatment on Goblet Cell Mucin and Immune Responses in the Chronic Allergic Eye Disease (AED) Model (2018) (20)
- Preventing injury from within, using selective cPLA2 inhibitors (2000) (20)
- Fundamentals of Inflammation: Lipid Mediators in Acute Inflammation and Resolution: Eicosanoids, PAF, Resolvins, and Protectins (2010) (19)
- Pro-resolving lipid mediator lipoxin A4 attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome (2021) (19)
- Clues for new therapeutics in osteoporosis and periodontal disease: new roles for lipoxygenases? (2004) (18)
- Native and aspirin-triggered lipoxins control innate immunity by inducing proteasomal degradation of TRAF6 (2008) (18)
- The need for precision nutrition, genetic variation and resolution in Covid-19 patients (2021) (18)
- Resolvin T-series reduce neutrophil extracellular traps (2021) (18)
- New mechanism for an old drug Aspirin triggers anti-inflammatory lipid mediators with gender implications (2006) (17)
- Lipoxins and aspirin-triggered lipoxins in airway responses. (2003) (17)
- Oxidoreductases in Lipoxin A4 Metabolic Inactivation. A Novel Role for 15-oxoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in Inflammation (2000) (17)
- Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2 (2018) (17)
- Appearance of an arachidonic acid 15‐lipoxygenase pathway upon differentiation of the human promyelocytic cell‐line HL‐60 (1985) (17)
- Aspirin triggers formation of anti-inflammatory mediators: New mechanism for an old drug. (2004) (16)
- Identification of a human enterocyte lipoxin a receptor that is regulated by IL-13 and IFN-γ and inhibits TNF-α-induced IL-8 release (1999) (16)
- Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 modulate adhesion molecule expression on human leukocytes in whole blood and inhibit neutrophil-endothelial cell adhesion. (2002) (16)
- Local and Systemic Delivery of an Aspirin‐Triggered Lipoxin Stable Analog Inhibits Neutrophil Trafficking (2000) (16)
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- A Role for PPAR (2001) (15)
- Vacuolar (H+)-ATPase Critically Regulates Specialized Proresolving Mediator Pathways in Human M2-like Monocyte-Derived Macrophages and Has a Crucial Role in Resolution of Inflammation (2019) (15)
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- Specialized Proresolving Mediators Rescue Infant Mice from Lethal Citrobacter rodentium Infection and Promote Immunity against Reinfection (2017) (12)
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- Bang and Dyerberg’s omega-3 discovery turns fifty (2021) (7)
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- Lipoxin and leukotriene production during receptor-activated interactions between human platelets and cytokine-primed neutrophils. (1991) (4)
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- LXA4, aspirin-triggered 15-epi-LXA4, and their analogs selectively downregulate PMN azurophilic degranulation. (1999) (4)
- A Newly Synthesized 17-epi-Neuroprotectin D1/17-epi-Protectin D1: Authentication and Functional Regulation of Inflammation-Resolution. (2022) (3)
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- Pro‐Resolving Lipid Mediators and Anti‐Angiogenic Therapy Exhibit Synergistic Anti‐Tumor Activity via Resolvin Receptor Activation (2020) (3)
- Lipoxins trigger the release but not the oxygenation of arachidonic acid in human neutrophils: dissociation between lipid remodeling and adhesion. (1991) (3)
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- Aspirin-triggered 15-epi-lipoxin A4 biosynthesis in rat liver cells. (2002) (3)
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- First stereoselective total synthesis of 4(S),5(S)-oxido-17(S)-hydroxy-6(E),8(E),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid, the biosynthetic precursor of resolvins D3 and D4 (2022) (2)
- Transcellular biosynthesis of leukotriene B4 orchestrates neutrophil swarming to fungi (2022) (2)
- Aspirin-Triggered Lipoxin Agonist (ATLa) Inhibits Corneal Angiogenesis (2007) (2)
- The allergy archives: pioneer and milestones. The discovery and characterization of the leukotrienes. (2006) (2)
- CORRIGENDUM: Novel n-3 Immunoresolvents: Structures and Actions (2014) (2)
- Resolvin D4 Potent Antiiinflammatory Proresolving Actions Confirmed via Total Synthesis (2015) (2)
- ALTERED LIPID MEDIATORS AND RECEPTORS OF RESOLUTION IN THE ENTORHINAL CORTEX OF ALZHEIMER'S DISEASE (2014) (2)
- Macrophages and the Entrance of Resolution Phase Lipid Mediators (2014) (2)
- A Novel Polyisoprenyl Phosphate Signaling Cascade in Human Neutrophils (2000) (2)
- Author Correction: ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance (2018) (2)
- Staphylococcus aureus controls eicosanoid and specialized pro‐resolving mediator production via lipoteichoic acid (2022) (2)
- Characterisation of the binding of leukotriene B4 to macrophages of the rainbow trout Oncorhynchus mykiss. (1997) (2)
- Mechanism for Resolution of Inflammation A in Human Neutrophils : A Novel AmyloidApoptosis-Delaying Action of Serum Aspirin-Triggered Lipoxins Override the (2007) (2)
- counterregulates leukocytes and platelets Resolvin E1, an EPA-derived mediator in whole blood, selectively (2008) (2)
- Anti-Inflammatory and Pro-Resolving Lipid Mediators (2009) (2)
- Cytokines and Chemokines in Inflammation and Cancer (2010) (2)
- CHAPTER 169 – Lipoxins and Aspirin-Triggered 15-epi-Lipoxins: Mediators in Anti-inflammation and Resolution (2003) (2)
- Sex-based differences in conjunctival goblet cell responses to pro-inflammatory and pro-resolving mediators (2022) (2)
- A Novel Series of Biologically Active Compounds (1985) (2)
- rapid communication LXA 4 , aspirin-triggered 15-epi-LXA 4 , and their analogs selectively downregulate PMN azurophilic degranulation (1999) (1)
- The Specialized Pro‐resolving Lipid Mediator Resolvin E1 Promotes Intestinal Mucosal Wound Repair (2016) (1)
- Abstract 10968: Neuroprotectin D1 Induces Protection After Brain Ischemic Injury in a Mouse Stroke Model by Blocking Mitochondria-mediated Cell Death Pathways (2019) (1)
- E. coli peritonitis initiates D‐series Resolvin‐metabolome (2013) (1)
- Synthesis and Anti-in fl ammatory and Pro-resolving Activities of 22-OH-PD 1 , a Monohydroxylated Metabolite of Protectin D 1 (2014) (1)
- Inhibition of Neutrophil-Endothelial Interactions in Human Whole Blood: Modulation of Leukocyte Adhesion Molecules and Anti-Inflammatory Actions of Lipoxin A4 Stable Analogs Are Demonstrable (2013) (1)
- Dietary omega-3 polyunsaturated fatty acids plus aspirin decreases plasma lipids and increases pro-resolving lipid mediators in apoE-deficient mice (2014) (1)
- Relieving the Itch (1998) (1)
- 3 Polyunsaturated fatty acids (PUFAs) and specialized pro-resolving mediators (SPMs) are decreased in plasma and serum from SLE patients compared to healthy controls (2019) (1)
- Signaling Pathways Used by the Specialized Pro-Resolving Mediator Maresin 2 Regulate Goblet Cell Function: Comparison with Maresin 1 (2022) (1)
- On the generation of lipoxins and novel related compounds by human neutrophils: relationship to leukotriene production. (1989) (1)
- Evidence for the presence and diagnostic utility of SPM in human peripheral blood (2022) (1)
- Novel Peptide‐Conjugated Maresins Stimulate Tissue Regeneration and Clearance of Infections in Planaria and Inflammatory Exudates (2015) (1)
- Synergy between Resolvins and Immune Checkpoint Blockade in a Novel Transplantable FANCC−/− Murine Head and Neck Tumor Model (2019) (1)
- Formylpeptide receptors in GtoPdb v.2021.2 (2021) (1)
- Endogenous specialized proresolving mediators enhance antigen-specific antibody response against influenza virus: A new class of adjuvant (P4285) (2013) (1)
- LIPID MEDIATORS | Lipoxins (2006) (1)
- Polyisoprenyl phosphates: a novel class of intracellular stop signals in neutrophils (1998) (1)
- Lipoxin Generation in Human Whole Blood: Monitoring by Electron-Capture NICI GC/MS (1991) (1)
- Lipoxin metabolism by human promyelocytic leukemia (HL-60) cells. (1997) (1)
- Aspirin‐triggered lipoxins enhance resolution of myeloperoxidase‐mediated lung inflammation by promoting neutrophil apoptosis (2009) (1)
- Neuroprotectin D1 Attenuates Blast Overpressure Induced Reactive Microglial Cells in the Cochlea (2021) (1)
- Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Novel Pro‐resolving Mediators and Heme Oxygenase‐1 (2013) (1)
- Maresin 1 a Novel Macrophage n‐3 Derived Mediator is a Potent Tissue Regenerative Immunoresolvent (2013) (1)
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- Resolvin D1 Programs Myocardial Infarction‐induced Cardiorenal Syndrome in Heart Failure Pathology (2017) (1)
- Roles of Specialized Proresolving Lipid Mediators in Inflammation Resolution and Tissue Repair (2017) (1)
- Chemical Mediators of Inflammation and Resolution in Post-Operative Abdominal Aortic Aneurysm Patients (2011) (1)
- Mediator-lipidomics: Published, JLR Papers in Press, February 1, 2005. DOI 10.1194/jlr.D400020-JLR200databases and search algorithms for PUFA-derived mediatorss⃞s⃞ The online version of this article (available at http://www.jlr.org) contains supplemental data. (2005) (1)
- Novel pro-resolving lipid mediator mimetic 3-oxa-PD1n-3 DPA reduces acute and chronic itch by modulating excitatory and inhibitory synaptic transmission and astroglial secretion of lipocalin-2 in mice. (2022) (1)
- Erratum to: Chemical Mediators of Inflammation and Resolution in Post-Operative Abdominal Aortic Aneurysm Patients (2011) (1)
- Resolvin D1 Attenuates Cigarette Smoke-Induced Lung Inflammation By Upregulating Alternatively Activated Macrophages (M2) With Anti-Inflammatory And Pro-Resolving Properties (2011) (1)
- Plasma high‐resolution metabolomic profiling reveals upregulation of specific resolvins in patients with pulmonary tuberculosis (248.3) (2014) (1)
- Endogenous Anti-inflammatory and Proresolving Lipid Mediators in Renal Disease (2011) (1)
- From GWAS to Therapy: Fatty Acid Synthase in Uterine Leiomyomata (2015) (1)
- Leukotriene receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (1)
- Specialized Pro‐Resolving Lipid Derived Fatty Acid Mediators: Wiring the Circuitry of Effector Immune Homeostasis (2013) (1)
- THEMED SECTION: MEDIATORS AND RECEPTORS IN THE RESOLUTION OF INFLAMMATION RESEARCH PAPER Resolvin D1 controls inflammation initiated by glutathione-lipid conjugates formed during oxidative stress (2009) (1)
- Lipoxins and Related Eicosanoids: Biosynthesis, Chemical Synthesis and Biological Properties (1991) (1)
- Resolution of Inflammation in the Lesioned Central Nervous System (2015) (1)
- Resolvin D2 and Resolvin D1 Differentially Activate Protein Kinases to Counter-Regulate Histamine-Induced [Ca2+]i Increase and Mucin Secretion in Conjunctival Goblet Cells (2021) (1)
- Lipoxin (LX)A 4 and Aspirin-triggered 15-epi-LXA 4 Inhibit Tumor Necrosis Factor 1 (cid:97) –initiated Neutrophil Responses and Trafficking: Regulators of a Cytokine–Chemokine Axis (1999) (1)
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- Pro-Inflammatory Leukotriene LTD4-Stimulated Conjunctival Goblet Cell Secretion Is Blocked by the Resolvins RvE1 and RvD1 (2009) (0)
- Lipoxin A4 Inhibits Histamine-stimulated Increase in [Ca2+], ERK Activation, and Mucin Secretion in Cultured Rat Conjunctival Goblet Cells (2014) (0)
- of Inflammation Resolvins D1 and E1 To Promote Resolution Stimulated by Leukotrienes Is Reduced by Conjunctival Goblet Cell Secretion (2011) (0)
- Abstract 1664: Cancer progression: The failure to resolve (2014) (0)
- Stimulating the Resolution of Tumor Debris to Control Medulloblastoma (2015) (0)
- Resolvins attenuate cigarette smoke-induced lung inflammation and injury (120.31) (2012) (0)
- ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance (2017) (0)
- Abstract 1170: Maresin 1: a potent endogenous anti-inflammatory and pro-resolving inhibitor of primary tumor growth and metastasis (2014) (0)
- Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis (2023) (0)
- Concurrent Eosinophilia Infected Rats : Relationship with costaricensis-Angiostrongylus Allergic Edema in Accelerate Resolution of 4 and Lipoxin A 2 Cyclooxygenase-2-Derived Prostaglandin E (1999) (0)
- Translational Research in Acute Lung Injury and Pulmonary Fibrosis Proresolving actions of a new resolvin D 1 analog mimetic qualifies as an immunoresolvent (2015) (0)
- ISNN Society News (2010) (0)
- Identification of Signaling Pathways Utilized by Leukotrienes D4 and E4 to Stimulate Rat Conjunctival Cell Secretion and Resolvins RvD1 and RvE1 to Block It (2011) (0)
- ISNN Society News (2012) (0)
- Proresolving Mediators Resolution in the Mucosa: A Role for Antimicrobial Aspects of Inflammatory (2015) (0)
- Dexamethasone, pro-resolving lipids and resolution of inflammation in COVID-19 (2020) (0)
- Resolvin D1 and Resolvin D5 Lower Antibiotic Doses in Infection (2013) (0)
- ISSN Society News (2016) (0)
- ISNN Society News (2013) (0)
- epithelial bactericidal/permeability-increasing protein Functional and biochemical characterization of (2012) (0)
- Use of lipoxin 4? and its derivatives as antagonists for trägreagierende anaphylaxmittel (1990) (0)
- Neural Inflammation, Alzheimer's Disease, and Stroke (2010) (0)
- 14-hydroxy-docosahexaensäurenverbindungen (2009) (0)
- SAT0026 Pro-Resolving and Cartilage-Protective Actions of Resolvin D1 in Inflammatory Arthritis (2016) (0)
- Lipoxin A4 Inhibits Histamine‐stimulated Increase in [Ca2+] and Mucin Secretion in Cultured Rat and Human Goblet Cells (2015) (0)
- Author Correction: Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological validation (2019) (0)
- Erratum to: Chemical Mediators of Inflammation and Resolution in Post-Operative Abdominal Aortic Aneurysm Patients (2011) (0)
- Author Correction: ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance (2018) (0)
- Resolvins D3, D4, and D5 activate selective signaling pathways to increase intracellular [Ca2+] in rat conjunctival goblet cells (2021) (0)
- Faculty Opinions recommendation of Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase. (2008) (0)
- Satiated-efferocytosis: A novel functional property for resolution-phase macrophages regulated by glucocorticoids, resolvins, galectin-1 and the chemokine-scavenging receptor D6 (P4157) (2013) (0)
- New Class of Adjuvant ? Immune Response against Influenza Virus : A 17-HDHA Enhances the Antibody-Mediated The Specialized Proresolving Mediator (2014) (0)
- , Election Outcomes Inferences of Competence from Faces Predict (2009) (0)
- Putting the brakes on neutrophils (2006) (0)
- Fish oil supplementation in patients with and without systemic lupus erythematosus: targeting pro-inflammatory and pro-resolving lipid mediators. (2022) (0)
- Kidney Glomerulonephritis and Renal Ischemia (2010) (0)
- Specialized proresolution mediators enhance human B cell differentiation to antibody secreting cells (53.10) (2012) (0)
- Cell Adhesion Molecules (2010) (0)
- Mechanism of Neuroprotectin D1 Action after Hypoxic‐Ischemic Injury in Neonatal Mice (2017) (0)
- Resolvin D1 Reduces Emphysema and Chronic (2015) (0)
- Experimental Models of Glomerulonephritis (2010) (0)
- S1747 Rsolvin E1, An Endogenous Lipid Mediator Derived from Eicosapentaenoic Acid Protects in Dextran Sulfate Sodium Induced Colitis (2008) (0)
- Targeting debris‐stimulated angiogenesis and primary tumor growth by resolvin mediated clearance (2017) (0)
- Nutrients and Gene Expression in Inflammation (2020) (0)
- Lipoxin analog and new inhibitors of angiogenesis (2002) (0)
- ISNN Society News (2017) (0)
- ISSN Society News (2012) (0)
- Lipoxin A Attenuates Obe 4 sity-Induced Adipose Inflammation and Associated Liver and Kidney Disease Graphical (0)
- Abstract 1329: Maresins prevent breast cancer dormancy escape via resolution of inflammation (2022) (0)
- Abstract 323: Metabolic Transformation of Fatty Acids Defines Resolving Versus Non-Resolving Inflammation in Obesity-Associated Heart Failure (2017) (0)
- Leukotriene receptors (version 2020.3) in the IUPHAR/BPS Guide to Pharmacology Database (2020) (0)
- Inactivation during Inflammation-Resolution Resolvin E1 Metabolome in Local (2008) (0)
- Control of Lung Cancer with Aspirin‐Triggered Stimulation of Resolution (2015) (0)
- A Pregnant Woman Considering n − 3 Long-Chain Polyunsaturated Fatty Acid Supplementation (2016) (0)
- depotsof lipid mediators in human adipose tissue (2016) (0)
- Cover Picture: Total Synthesis of the Anti-inflammatory and Pro-resolving Lipid Mediator MaR1n−3 DPA Utilizing an sp3–sp3 Negishi Cross-Coupling Reaction (Chem. Eur. J. 45/2014) (2014) (0)
- Human Periodontal Stem Cells Release Specialized (2015) (0)
- Actions of novel inflammation-resolving lipid mediators on human B cells (112.12) (2010) (0)
- Phosphatidate and Fatty Acids Are Ca 2 ’ Ionophores 2737 (2001) (0)
- ISNN Membership Application Form (2012) (0)
- Protectins Inhibit Estrogen Receptor Negative Breast Cancer Growth in Mice (2022) (0)
- Inhibition of CHOP Chemotherapy‐stimulated Hematological Tumor Growth with Resolvins (2017) (0)
- ANALOGS OF OMEGA-3 PUFAs DERIVED LIPID MEDIATORS AND METHOD OF USE (2003) (0)
- Resolution medicine in cancer, infection, pain and inflammation: are we on track to address the next Pandemic? (2023) (0)
- Fundamentals of Inflammation: Preface (2010) (0)
- Release of pro-inflammatory chemokines from model intestinal epithelia is inhibited by lipoxin A4 analogs (1998) (0)
- Antimicroinflammatory Lipid Signals from Vascular Cyclooxygenase-2: A Novel Mechanism for NSAID and N-3 PUFA Therapeutic Actions (2001) (0)
- The Anti-Inflammatory And Pro-Resolving Lipid Mediator Resolvin D1 Regulates The Inflammatory Response In Lung Fibroblast And Epithelial Cells (2011) (0)
- Resolvin D1 Stable Analog Promotes Corneal Allograft Survival (2012) (0)
- Resolvin D1 protects from neutrophil mediated joint destruction in inflammatory arthritis (146.5) (2014) (0)
- ISNN Membership Application Form (2013) (0)
- Abstract 370: Potential of inflammation pro-resolving lipid mediators in controlling cancer cachexia (2023) (0)
- ISNN Society News (2014) (0)
- Total organic synthesis and stereochemical assignment of resolvin D3 and aspirin-triggered resolvin D3: potent immunoresolvents (2014) (0)
- Resolvin D1 inhibits multiple pro-inflammatory signaling pathways in primary human lung cells exposed to diverse inflammatory stimuli (IRM9P.721) (2014) (0)
- Aspirin-Triggered-15-Epi-Lipoxin A Inhibition by Neutrophil Chemotaxis and Recruitment : Cutting Edge : Nociceptin Stimulates (2001) (0)
- Cornea Resolvin D 1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways (2017) (0)
- MedicinesHost Response with Novel Nanoproresolving Inflammation in Mice: Reprogramming the Aging Delays Resolution of Acute (2014) (0)
- Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution (2007) (0)
- Circulating hydroxy fatty acids in I (neutrophil aggregation/lipoxygenase/icosanoids/colchicine) (2016) (0)
- ISSN Society News (2011) (0)
- Resolvin D1 Receptor Activation Counter‐regulates H1 histamine receptors in human and rat conjunctival goblet cells (2013) (0)
- Computed conformational analysis of lipoxins and their ionic complexes. (1988) (0)
- Oral abstracts 7: Molecular mechanisms of disease—osteoarthritisS1. Identification of novel osteoarthritis genes using zebrafish (2012) (0)
- Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity (2018) (0)
- ISNN Society News (2014) (0)
- Lipoxin A4 and aspirin-triggered 15-epi-LXA are protective in acute inflammation and reperfusion injury in leukotriene B4 receptor transgenic mice (1999) (0)
- Lipoxin A4, and aspirin-triggered 15-epi-LXA4 inhibit TNFα-initiated neutropail responses and trafficking: Regulators of a cytokinechemokine axis (1999) (0)
- ESI/LC-MS/MS Lipidomic analysis of hydroxy-fatty acid derivatives of polyunsaturated fatty acids. (2007) (0)
- Suppression of Cell Debris‐Stimulated Tumor Growth by Resolvin Mediated Clearance (2015) (0)
- Aspirin Switches Biosynthetic Circuits Triggering Novel Eicosanoids during Cell-Cell Interactions that Are Potent Inhibitors of Neutrophil Migration and Tumor Cell Proliferation (1996) (0)
- ISNN Society News (2012) (0)
- Short Communication Selectivity of Recombinant Human Leukotriene D 4 , Leukotriene B 4 , and Lipoxin A 4 Receptors with Aspirin-Triggered 15-epi-LXA 4 and Regulation of Vascular and Inflammatory Responses (2000) (0)
- Abstract 115: Aspirin-triggered Neuroprotectin D1 Protects The Penumbra In Focal Cerebral Ischemia In Rats (2012) (0)
- Tissue Homeostasis In Vivo Cellular and Tissue Level and Restores Resolvin E 1 Regulates Inflammation at the (2007) (0)
- Polyunsaturated Fatty Acids in Human Nutrition. Proceedings of a Workshop Held in Mexico City, Mexico, 27-30 November 1990.Umberto Bracco , Richard J. Deckelbaum (1993) (0)
- ISNN Society News (2010) (0)
- Brain Temperature of Rats (1993) (0)
- Histamine-Stimulated Conjunctival Goblet Cell Secretion is Blocked by the Resolvin RvD1 and the Aspirin-Triggered Resolvin 17 (R)-RvD1 (2010) (0)
- Bioactive -3 LCPUFA Derivatives, Resolvins and Neuroprotectins, Inhibit Neovascularization in Oxygen Induced Retinopathy (2007) (0)
- Gastrointestinal Inflammation and Ulceration: Mediators of Induction and Resolution (2010) (0)
- Resolvin D2 increases conjunctival goblet cell intracellular [Ca2+] by increasing cellular cAMP to activate protein kinase A (2017) (0)
- Functional Foods for Health Promotion : Moving Beyond “ Good Fat , Bad Fat ” Moving Beyond “ Good Fat , Bad Fat ” : The Complex Roles of Dietary Lipids in Cellular Function and Health 1 , 2 (2012) (0)
- Actions of novel inflammation-resolving lipid mediators on human B cells (84.9) (2010) (0)
- Brain Cancer: Failure of Resolution of Inflammation? (2019) (0)
- ISNN Membership Application Form (2014) (0)
- Contribution of Bidirectional Transcellular Routes to Lipoxin Biosynthesis (1993) (0)
- ISNN Society News (2015) (0)
- Changes of OCTA Findings after Treatment in Polypoidal Choroidal Vasculopathy (2018) (0)
- Lipoxins: "Biosynthesis, Chemistry, And Biological Activities" (2013) (0)
- Resolvins and Cysteinyl-containing Pro-Resolving Mediators Activate Resolution of Infectious Inflammation and Tissue Regeneration. (2023) (0)
- Cells and Epithelial Cells EndothelialTransmigration with Microvessel 15 Epimers in Chemotaxis and Migration : Comparisons Between Synthetic Inhibit Human Neutrophil 415-epi-Lipoxin A and Aspirin-Triggered 4 Lipoxin (2003) (0)
- Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D and superoxide anion generation in human neutrophils: Novel intracellular “stop” signals (1999) (0)
- Allergen-Induced Eosinophil Trafficking Block 4 Aspirin-Triggered 15-Epi-LXA and 4 Cutting Edge : Lipoxin ( LX ) A and (2000) (0)
- Targeting lipid mediators in cancer biology (2018) (0)
- Addendum: Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3 DPA. (2019) (0)
- 1102 Fish oil supplementation and pro-inflammatory and pro-resolving lipid mediators in patients with and without systemic lupus erythematosus (2021) (0)
- ISNN Society News (2013) (0)
- ISNN Society News (2015) (0)
- HyperresponsivenessDampens Airway Inflammation and Protectin D1 Is Generated in Asthma and (2006) (0)
- Novel Anti-Inflammatory and Proresolution Lipid Mediators in Induction and Modulation of Phagocyte Function (2009) (0)
- Leukocyte Generation of Reactive Oxygen Species (2010) (0)
- ISNN Society News (2013) (0)
- The Role of Specialized Pro-Resolving Mediators ( SPM ) on Inflammation (2015) (0)
- Lipoxins and resolvins: Local mediators in endogenous anti-inflammation and resolution (2004) (0)
- ISNN Membership Application Form (2013) (0)
- Aspirin‐triggered lipoxins override the apoptosis‐delaying action of myeloperoxidase in human neutrophils (2009) (0)
- THU0279 POLYUNSATURATED FATTY ACIDS (PUFAS) AND SPECIALIZED PRO-RESOLVING MEDIATORS (SPMS) ARE DECREASED IN PLASMA AND SERUM FROM SLE PATIENTS COMPARED TO HEALTHY CONTROLS (2019) (0)
- Formylpeptide receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
- Resolvins activate inflammation-resolution programs: a systems approach to resolution (2009) (0)
- Lipoxinanaloge as novel restenosis inhibitors (2002) (0)
- ISSN Society News (2012) (0)
- IMMU-13. A FAILURE TO RESOLVE INFLAMMATION: ROLE OF RESOLVINS IN THE TREATMENT OF PEDIATRIC CNS TUMORS (2018) (0)
- ISNN Society News (2015) (0)
- ISNN Society News (2014) (0)
- RvD2 stimulates conjunctival goblet cell secretion by activating multiple Ca2+‐dependent intracellular signaling pathways (2021) (0)
- Resolvins inhibit breast tumor progression by countering cancer stem cells (2022) (0)
- ISNN Society News (2011) (0)
- Resolvin D-series regulates Phospholipase D both during inflammation and resolution by modulating phagocyte functions (2019) (0)
- Elucidation of Resolvin and Protectin Sulfido‐Conjugated Mediators: New Pro‐Resolving and Tissue Regenerative Pathways (2015) (0)
- Induced Inflammation and Lung Injury − C 5 a-Dependent IgG Immune Complex-Fluorophenoxy-Resolvin D 1 Methyl Ester , in Para 17 R-Hydroxy-19-( 17 R ) Resolvin D 1 and Its Analogue , Protective Actions of Aspirin-Triggered Petasis (2014) (0)
- Stereocontrolled total synthesis of Resolvin D4 and 17(R)-Resolvin D4. (2022) (0)
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