Charles Nicholson
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Charles Nicholsonengineering Degrees
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Charles Nicholsoncomputer-science Degrees
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Engineering Computer Science
Charles Nicholson's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
- Bachelors Computer Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Charles Nicholson's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum. (1981) (814)
- Theory of current source-density analysis and determination of conductivity tensor for anuran cerebellum. (1975) (668)
- Clearance systems in the brain—implications for Alzheimer disease (2015) (632)
- In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space. (2006) (541)
- Experimental optimization of current source-density technique for anuran cerebellum. (1975) (452)
- Diffusion and related transport mechanisms in brain tissue (2001) (447)
- Clearance systems in the brain-implications for Alzheimer disease. (2015) (434)
- Extracellular ionic variations during spreading depression (1978) (392)
- Diffusion from an injected volume of a substance in brain tissue with arbitrary volume fraction and tortuosity (1985) (365)
- Electrophysiological properties of dendrites and somata in alligator Purkinje cells. (1971) (338)
- Alkaline and acid transients in cerebellar microenvironment. (1983) (328)
- Enhanced Striatal Dopamine Transmission and Motor Performance with LRRK2 Overexpression in Mice Is Eliminated by Familial Parkinson's Disease Mutation G2019S (2010) (325)
- Extracellular space parameters in the rat neocortex and subcortical white matter during postnatal development determined by diffusion analysis (1993) (280)
- Calcium and potassium changes in extracellular microenvironment of cat cerebellar cortex. (1978) (273)
- Calcium modulation in brain extracellular microenvironment demonstrated with ion-selective micropipette. (1977) (268)
- Hindered diffusion of high molecular weight compounds in brain extracellular microenvironment measured with integrative optical imaging. (1993) (256)
- Modulation by applied electric fields of Purkinje and stellate cell activity in the isolated turtle cerebellum. (1986) (251)
- Perspectives on spreading depression (2000) (231)
- Magnetic localization of neuronal activity in the human brain. (1988) (208)
- A model for the polarization of neurons by extrinsically applied electric fields. (1986) (199)
- Calcium role in depolarization-secretion coupling: an aequorin study in squid giant synapse. (1975) (196)
- Ion-selective microelectrodes and diffusion measurements as tools to explore the brain cell microenvironment (1993) (188)
- Generation and Dynamics of an Endogenous, Self-Generated Signaling Gradient across a Migrating Tissue (2013) (176)
- Brain Extracellular Space: The Final Frontier of Neuroscience. (2017) (175)
- Diffusion of epidermal growth factor in rat brain extracellular space measured by integrative optical imaging. (2004) (170)
- Interaction between diffusion and Michaelis-Menten uptake of dopamine after iontophoresis in striatum. (1995) (169)
- Effects of electric fields on transmembrane potential and excitability of turtle cerebellar Purkinje cells in vitro. (1988) (166)
- Extracellular potassium, volume fraction, and tortuosity in rat hippocampal CA1, CA3, and cortical slices during ischemia. (1995) (164)
- Diffusion from an iontophoretic point source in the brain: role of tortuosity and volume fraction (1979) (158)
- Dopamine-mediated volume transmission in midbrain is regulated by distinct extracellular geometry and uptake. (2001) (155)
- Extracellular volume decreases while cell volume is maintained by ion uptake in rat brain during acute hypernatremia. (1991) (148)
- Changes of extracellular potassium activity induced by electric current through brain tissue in the rat. (1983) (132)
- Ascorbate Inhibits Edema in Brain Slices (2000) (132)
- Theoretical analysis of field potentials in anisotropic ensembles of neuronal elements. (1973) (132)
- The Migration of Substances in the Neuronal Microenvironment a (1986) (132)
- Anion permeability in spreading depression investigated with ion-sensitive microelectrodes (1979) (130)
- Diffusion characteristics and extracellular volume fraction during normoxia and hypoxia in slices of rat neostriatum. (1991) (129)
- Aquaporin-4-Deficient Mice Have Increased Extracellular Space without Tortuosity Change (2008) (129)
- Changes in brain cell shape create residual extracellular space volume and explain tortuosity behavior during osmotic challenge. (2000) (129)
- Extracellular dopamine concentration in the retina of the clawed frog, Xenopus laevis. (1993) (125)
- In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate (2008) (118)
- Diffusion of albumins in rat cortical slices and relevance to volume transmission (1996) (114)
- Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum (1988) (113)
- Spatial buffering of potassium ions in brain extracellular space. (2000) (113)
- Field potentials in the alligator cerebellum and theory of their relationship to Purkinje cell dendritic spikes. (1971) (112)
- Potassium accumulation around individual purkinje cells in cerebellar slices from the guinea‐pig. (1983) (109)
- Anisotropic and heterogeneous diffusion in the turtle cerebellum: implications for volume transmission. (1993) (108)
- Intracellular Staining in Neurobiology (1973) (108)
- Diffusion of molecules in brain extracellular space: theory and experiment. (2000) (105)
- Measurement of nanomolar dopamine diffusion using low-noise perfluorinated ionomer coated carbon fiber microelectrodes and high-speed cyclic voltammetry. (1989) (101)
- Calcium diffusion enhanced after cleavage of negatively charged components of brain extracellular matrix by chondroitinase ABC (2009) (100)
- Water compartmentalization and extracellular tortuosity after osmotic changes in cerebellum of Trachemys scripta. (1996) (88)
- Brain extracellular space as a diffusion barrier (2011) (87)
- Signals that go with the flow (1999) (87)
- Reversal properties of climbing fiber potential in cat Purkinje cells: an example of a distributed synapse. (1976) (84)
- Dead-Space Microdomains Hinder Extracellular Diffusion in Rat Neocortex during Ischemia (2003) (83)
- Maximum geometrical hindrance to diffusion in brain extracellular space surrounding uniformly spaced convex cells. (2004) (80)
- Quantitative analysis of extracellular space using the method of TMA+ iontophoresis and the issue of TMA+ uptake. (1992) (80)
- Modulation of extracellular calcium and its functional implications. (1980) (78)
- Contribution of dead-space microdomains to tortuosity of brain extracellular space (2004) (76)
- Independence of extracellular tortuosity and volume fraction during osmotic challenge in rat neocortex (2002) (68)
- Magnetic field associated with spreading depression: a model for the detection of migraine (1988) (60)
- Cell cavities increase tortuosity in brain extracellular space. (2005) (60)
- Origin of the apparent tissue conductivity in the molecular and granular layers of the in vitro turtle cerebellum and the interpretation of current source-density analysis. (1994) (60)
- Tetrodotoxin resistant propagation and extracellular sodium changes during spreading depression in rat cerebellum (1982) (59)
- Use of Ion-Selective Microelectrodes and Voltammetric Microsensors to Study Brain Cell Microenvironment (1988) (58)
- Factors governing diffusing molecular signals in brain extracellular space (2004) (57)
- Diffusion of flexible random-coil dextran polymers measured in anisotropic brain extracellular space by integrative optical imaging. (2008) (56)
- Real time current source-density analysis using multi-electrode array in cat cerebellum (1975) (55)
- Poly[N-(2-hydroxypropyl)methacrylamide] polymers diffuse in brain extracellular space with same tortuosity as small molecules. (2001) (55)
- Comparative neurophysiology of spreading depression in the cerebellum. (1984) (55)
- Long distance pathways of diffusion for dextran along fibre bundles in brain. Relevance for volume transmission (1995) (52)
- The three‐dimensional point spread functions of a microscope objective in image and object space (1995) (50)
- Biophysical Properties of Brain Extracellular Space Explored with Ion-Selective Microelectrodes, Integrative Optical Imaging and Related Techniques (2007) (49)
- Direct monitoring of dopamine and 5-HT release in substantia nigra and ventral tegmental area in vitro (1994) (47)
- Large potassium signals and slow potentials evoked during aminopyridine or barium superfusion in cat cerebellum (1976) (47)
- Measurement of extracellular ions in the brain (1980) (47)
- Space–Time Transformation in the Frog Cerebellum through an Intrinsic Tapped Delay-line (1970) (45)
- Diffusion and Ion Shifts in the Brain Extracellular Microenvironment and Their Relevance for Voltammetric Measurements (1995) (44)
- Sodium liquid ion exchanger microelectrode used to measure large extracellular sodium transients. (1976) (43)
- Distortion of magnetic evoked fields and surface potentials by conductivity differences at boundaries in brain tissue. (1990) (43)
- Diffusion in the slice microenvironment and implications for physiological studies. (1983) (43)
- Magnetic evoked field associated with transcortical currents in turtle cerebellum. (1988) (42)
- Theory relating in vitro and in vivo microdialysis with one or two probes (2002) (41)
- Calcium decrease associated with aminopyridine-induced potassium increase in cat cerebellum (1976) (40)
- MEG source models and physiology. (1987) (40)
- Quantitative dual‐probe microdialysis: evaluation of [3H]mannitol diffusion in agar and rat striatum (2002) (38)
- Chloride and potassium changes measured during spreading depression in catfish cerebellum (1975) (37)
- Multimodal characterization of population responses evoked by applied electric field in vitro: extracellular potential, magnetic evoked field, transmembrane potential, and current-source density analysis (1991) (36)
- Magnetic field associated with neural activities in an isolated cerebellum (1987) (36)
- Optical Current Source Density Analysis in Hippocampal Organotypic Culture Shows That Spreading Depression Occurs with Uniquely Reversing Currents (2005) (35)
- A Guide to Intracellular Staining Techniques (1973) (34)
- Water Compartmentalization and Spread of Ischemic Injury in Thick-Slice Ischemia Model (2002) (33)
- Ion Measurements in Physiology and Medicine (1985) (33)
- Interstitial Ascorbate in Turtle Brain Is Modulated by Release and Extracellular Volume Change (1987) (33)
- Calcium diffusion in the brain cell microenvironment. (1987) (33)
- Light scattering in rat neocortical slices differs during spreading depression and ischemia (2002) (32)
- Dextran Decreases Extracellular Tortuosity in Thick-Slice Ischemia Model (2000) (32)
- Brain Extracellular Space: Geometry, Matrix and Physiological Importance (2013) (31)
- Equilibrium Potential for the Postsynaptic Response in the Squid Giant Synapse (1974) (31)
- Regulation of intracellular pH in vertebrate central neurons (1985) (30)
- Erratum: Clearance systems in the brain—implications for Alzheimer diseaser (2016) (28)
- Quantitative dual‐probe microdialysis: mathematical model and analysis (2002) (27)
- Extracellular Potassium, Calcium and Volume Profiles During Spreading Depression (1981) (26)
- Behavior of extracellular K+ and pH in skate (Raja erinacea) cerebellum (1988) (26)
- Threshold extracellular concentration distribution of penicillin for generation of epileptic focus measured by diffusion analysis (1991) (25)
- Superfusion of verapamil on the cerebral cortex does not suppress epileptic discharges due to restricted diffusion (rats, in vivo) (1993) (22)
- Diffusion of penicillin in agar and cerebral cortex of the rat (1988) (21)
- Interactions between insulin and diet on striatal dopamine uptake kinetics in rodent brain slices (2018) (21)
- Inhibition of Purkinje cells in the cerebellum of elasmobranch fishes. (1969) (20)
- Volume transmission in the year 2000. (2000) (19)
- Critical volume of rat cortex and extracellular threshold concentration for a pentylenetetrazol-induced epileptic focus (1997) (18)
- Diffusion analysis of valproate andtrans-2-en-valproate in agar and in cerebral cortex of the rat (1993) (17)
- Glutamate- and aspartate-induced extracellular potassium and calcium shifts and their relation to those of kainate, quisqualate and n-methyl-d-aspartate in the isolated turtle cerebellum (1990) (16)
- Real-time Iontophoresis with Tetramethylammonium to Quantify Volume Fraction and Tortuosity of Brain Extracellular Space. (2017) (15)
- Characterizing molecular probes for diffusion measurements in the brain (2008) (13)
- Issues involved in the transmission of chemical signals through the brain extracellular space. (1988) (13)
- Hydrogen Ion Variations and Their Interpretation in the Microenvironment of the Vertebrate Brain (1985) (13)
- The Development of Intracellular Staining (1973) (12)
- Magnetoencephalography (MEG) as a New Tool for Non-invasive Real-time Analysis of Normal and Abnormal Brain Activity in Humans (1989) (11)
- Potassium, calcium, chloride and sodium changes in extracellular space during spreading depression in cerebellum [proceedings]. (1978) (9)
- Rapid volume pulsation of the extracellular space coincides with epileptiform activity in mice and depends on the NBCe1 transporter (2021) (9)
- Anomalous diffusion inspires anatomical insights. (2015) (8)
- Measurement of diffusion parameters using a sinusoidal iontophoretic source in rat cortex (2002) (8)
- Reduction of Dimensionality in Monte Carlo Simulation of Diffusion in Extracellular Space Surrounding Cubic Cells (2019) (7)
- Climbing fiber evoked potassium release in cat cerebellum (1976) (7)
- Microelectrodes for Novel Anions and their Application to Some Neurophysiological Problems (1981) (7)
- Diffusion of anions and cations in the extracellular micro-environment of the brain [proceedings]. (1979) (6)
- Measurements of extracellular potassium and calcium concentration during passage of current across the surface of the brain [proceedings]. (1978) (6)
- Detection of Magnetic Fields from Isolated Avian Retina During Spreading Depression (1992) (5)
- The quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher (2015) (5)
- Diffusion properties of brain tissue measured with electrode methods and prospects for optical analysis. (1993) (4)
- Direct monitoring of dopamine and 5-HT release in substantia nigra and ventral tegmental area in vitro (2004) (4)
- Volume and ion regulation in both intracellular and extracellular compartments determined by diffusion, gravimetric and ion analysis. (1989) (4)
- Conductivity Boundaries May Produce Stronger Magnetic Fields than the Primary Source: Comparison of Three Analytical Methods (1989) (4)
- Modeling brain extracellular space from diffusion data (2007) (3)
- Brain Interstitial Structure Revealed Through Diffusive Spread of Molecules (2018) (3)
- Introduction: Special Issue in Honor of Eva Syková (2019) (2)
- The relationship between the geometry and extracellular volume fraction in an isolated brain tissue (1992) (2)
- Rice Uptake Is Regulated by Distinct Extracellular Geometry and Dopamine-Mediated Volume Transmission in Midbrain (2001) (2)
- Probing the Extracellular Space of Brain Slices with Ion-Selective Microelectrodes (1984) (2)
- Structure and Function of the Cellular Elements in the Central Nervous System (1998) (1)
- Comparative Study of Transmembrane Potential and Magnetic Evoked Field Due to Applied Electric Field in the Turtle Cerebellum (1989) (1)
- The quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher (2015) (1)
- Communicational aspects of neuronal circuitry in the cerebellar cortex of the alligator (1968) (1)
- Dirt-storing behavior by White-breasted Nuthatches (1991) (1)
- Central Mississippi Valley Earthquakes - 1978 (1980) (1)
- Recent English Ecclesiastical Architecture (2011) (1)
- Applications of a superconducting detector for measurements of the magnetic field associated with cellular currents in in vitro brain preparations (1988) (0)
- Integrative optical imaging of molecular diffusion in strong light scattering brain tissue (2015) (0)
- Fluid Spaces of the Brain Fluid–brain Interfaces Signals That Go with the Flow Targets at the Interface Looking for Signals (0)
- Neocortex Studied With Integrative Optical Imaging Effects of Osmotic Stress on Dextran Diffusion in Rat (2015) (0)
- Anisotropic diffusion of flexible random-coil polymers measured inbrain extracellular space by integrative optical imaging (2016) (0)
- Magnetic localization ofneuronal activity inthehumanbrain (1988) (0)
- Measurement of local diffusion properties in brain tissue (2016) (0)
- Extracellular Diffusion in Oriented Bundles of Brain Fibers with Variable Volume Fraction (2011) (0)
- Calcium Role in Depolarization-Secretion in Squid Giant Synapse (tetraethylammonium/tetrodotoxin/suppression potenti (2016) (0)
- Distortion ofmagnetic evokedfields andsurface potentials by conductivity differences atboundaries inbrain tissue (1990) (0)
- New and Notable Anomalous Diffusion Inspires Anatomical Insights (2015) (0)
- Reduction of Dimensionality in Monte Carlo Simulation of Diffusion in Extracellular Space Surrounding Cubic Cells (2019) (0)
- Modeling Calcium Diffusion in Chondroitin Sulfate using a Bimolecular Reaction Scheme (2013) (0)
- Theoretical Analysisof Field Potentials in Anisotropic EnsemblesofNeuronalElements (1973) (0)
- Calcium modulation inbrainextracellular microenvironment demonstrated withion-selective micropipette (rat cerebellum/repetitive stimulation/spreading depression/anoxia/potassium) (1977) (0)
- Calcium modulation in brain extracellular microenvironment (0)
- Dead spaces hinder diffusion and contribute to tortuosity of brain extracellular space (2016) (0)
- The Open-Access Journal for the Basic Principles of Diffusion Theory , Experiment and Application Modeling Ca 2 + diffusion in brain extracellular space (2013) (0)
- iffusion in B rain E xtracellular S pace (2011) (0)
- Diffusion from Point-Source in Oriented Fiber Ensembles with Different Volume Fractions (2011) (0)
- Calcium RoleinDepolarization-Secretion Coupling: AnAequorin Study (1975) (0)
- The Jamaica Earthquake (1907): Discussion (1908) (0)
- Summary of southeastern group breakout sessions (1993) (0)
- Introduction: Special Issue in Honor of Eva Syková (2019) (0)
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Charles Nicholson is affiliated with the following schools:
