Charles Weissmann | Academic Influence

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Charles Weissmann

Biology

#131

World Rank

#239

Historical Rank

Molecular Biology

#36

World Rank

#36

Historical Rank

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Biology

Charles Weissmann's Degrees

PhD Biochemistry University of Zurich

Why Is Charles Weissmann Influential?

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According to Wikipedia, Charles Weissmann is a Hungarian-Swiss molecular biologist. Weissmann is particularly known for the first cloning and expression of interferon and his contributions to the unraveling of the molecular genetics of neurogenerative prion diseases such as scrapie, Creutzfeldt–Jakob disease and "mad cow disease".

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Charles Weissmann's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A rapid, sensitive, and specific method for the determination of protein in dilute solution. (1973) (2117)
Mice devoid of PrP are resistant to scrapie (1993) (2080)
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein (1992) (1654)
A cellular gene encodes scrapie PrP 27-30 protein (1985) (1496)
Prion protein (PrP) with amino‐proximal deletions restoring susceptibility of PrP knockout mice to scrapie. (1996) (897)
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene (1986) (824)
Normal host prion protein necessary for scrapie-induced neurotoxicity (1996) (776)
Mapping of RNA by a modification of the Berk-Sharp procedure: the 5' termini of 15 S beta-globin mRNA precursor and mature 10 s beta-globin mRNA have identical map coordinates. (1979) (773)
Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase. (1995) (696)
Expression of Amino-Terminally Truncated PrP in the Mouse Leading to Ataxia and Specific Cerebellar Lesions (1998) (546)
Nucleotide sequence heterogeneity of an RNA phage population (1978) (525)
Mx protein: Constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virus (1986) (455)
Synthesis in E. coli of a polypeptide with human leukocyte interferon activity (1980) (421)
A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis. (1997) (406)
Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells (1983) (396)
The structure of one of the eight or more distinct chromosomal genes for human interferon-α (1980) (385)
Darwinian Evolution of Prions in Cell Culture (2010) (374)
Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. (2000) (372)
Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF‐1 and NF‐κB (1997) (368)
The state of the prion (2004) (362)
A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions (2003) (340)
Behavioral and anatomical deficits in mice homozygous for a modified β-amyloid precursor protein gene (1994) (317)
Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA (1986) (305)
A 'unified theory' of prion propagation (1991) (305)
No propagation of prions in mice devoid of PrP (1994) (301)
PrP expression in B lymphocytes is not required for prion neuroinvasion (1998) (282)
Prion Protein Devoid of the Octapeptide Repeat Region Restores Susceptibility to Scrapie in PrP Knockout Mice (2000) (277)
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain (1997) (272)
Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain (2001) (267)
Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system. (1996) (260)
A minimal intron length but no specific internal sequence is required for splicing the large rabbit β-globin intron (1984) (254)
Human leukocyte and fibroblast interferons are structurally related (1980) (251)
The interferon genes. (1986) (246)
High Prion and PrPSc Levels but Delayed Onset of Disease in Scrapie-Inoculated Mice Heterozygous for a Disrupted PrP Gene (1994) (243)
At least three human type alpha interferons: structure of alpha 2. (1980) (228)
The proportion of revertant and mutant phage in a growing population, as a function of mutation and growth rate. (1976) (220)
Prion research: the next frontiers (1997) (218)
Organization of the murine Mx gene and characterization of its interferon- and virus-inducible promoter (1988) (217)
Astrocyte‐specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie (1997) (213)
Prion strain discrimination in cell culture: The cell panel assay (2007) (213)
Infectivity of Scrapie Prions Bound to a Stainless Steel Surface (1999) (210)
Mice devoid of interferon regulatory factor 1 (IRF‐1) show normal expression of type I interferon genes. (1994) (206)
Transmission of Scrapie by Steel-surface-bound Prions (2001) (199)
Chronic Lymphocytic Inflammation Specifies the Organ Tropism of Prions (2005) (197)
Induction of mRNA for a serine protease and a beta-thromboglobulin-like protein in mitogen-stimulated human leukocytes. (1987) (196)
Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence. (1979) (180)
Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein. (1999) (172)
5′ cleavage site in eukaryotic pre-mRNA splicing is determined by the overall 5′ splice region, not by the conserved 5′ GU (1987) (172)
Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit β-globin gene (1983) (171)
Qβ DNA-containing hybrid plasmids giving rise to Qβ phage formation in the bacterial host (1978) (170)
Target cell specificity of two species of human interferon-alpha produced in Escherichia coli and of hybrid molecules derived from them. (1981) (168)
Differential expression of human interferon genes. (1984) (168)
The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor. (1978) (158)
PrP knock-out and PrP transgenic mice in prion research. (2003) (158)
Transmission of prions (2002) (157)
Molecular biology of transmissible spongiform encephalopathies (1996) (157)
DNA sequences preceding the rabbit beta-globin gene are required for formation in mouse L cells of beta-globin RNA with the correct 5' terminus. (1981) (150)
Secretion of interferon by Bacillus subtilis. (1983) (147)
A 46-nucleotide promoter segment from an IFN-α gene renders an unrelated promoter inducible by virus (1985) (147)
Subunit Structure of Qβ Replicase (1970) (140)
Structure and function of phage RNA. (1973) (138)
Rabbit β-globin mRNA production in mouse L cells transformed with cloned rabbit β-globin chromosomal DNA (1979) (137)
Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells. (1996) (137)
Different pathways mediate virus inducibility of the human IFN-α1 and IFN-β genes (1990) (129)
The nucleotide sequence of a cloned human leukocyte interferon cDNA. (1980) (129)
Reconstitution of Q replicase lacking subunit with protein-synthesis-interference factor i. (1972) (128)
Structure and expression of cloned murine IFN-α genes (1983) (128)
Comparison of cloned rabbit and mouse β-globin genes showing strong evolutionary divergence of two homologous pairs of introns (1978) (128)
Sequence of the First 175 Nucleotides from the 5′ Terminus of Qβ RNA synthesized in vitro (1969) (123)
Hybrid plasmids containing an active thymidine kinase gene of Herpes simplex virus 1. (1979) (118)
In vitro site-directed mutagenesis: generation and properties of an infectious extracistronic mutant of bacteriophage Qbeta. (1976) (116)
Replication of viral ribonucleic acid. IX. Properties of double-stranded RNA from Escherichia coli infected with bacteriophage MS2. (1966) (115)
The prion's progress (1991) (115)
Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication. (1999) (113)
REPLICATION OF VIRAL RNA, III. DOUBLE-STRANDED REPLICATIVE FORM OF MSW PHAGE RNA. (1964) (105)
An enzyme-detergent method for effective prion decontamination of surgical steel. (2005) (104)
Mapping of biological functions on RNA of avian tumor viruses: location of regions required for transformation and determination of host range. (1975) (102)
Prions on the move (2011) (102)
PrP‐dependent association of prions with splenic but not circulating lymphocytes of scrapie‐infected mice (1999) (101)
The isolation of plasmids containing DNA complementary to messenger RNA for variant surface glycoproteins of Trypanosoma brucei. (1980) (101)
Purification of globin messenger RNA from dimethylsulfoxide-induced Friend cells and detection of a putative globin messenger RNA precursor. (1976) (97)
The readthrough protein A1 is essential for the formation of viable Q beta particles. (1974) (92)
Single amino acid changes that render human IFN‐alpha 2 biologically active on mouse cells. (1987) (91)
Effect of mutations at the lariat branch acceptor site on β-globin pre-mRNA splicing in vitro (1986) (90)
Approaches to therapy of prion diseases. (2005) (89)
In vitro synthesis of phage RNA: the nature of the intermediates. (1968) (88)
Abnormal expression of chromosomal rabbit β-globin gene in Saccharomyces cerevisiae (1980) (86)
Evidence against a scanning model of RNA splicing. (1983) (86)
Reversible silencing of enhancers by sequences derived from the human IFN-α promoter (1987) (84)
Site-directed mutations in the initiator region of the bacteriophage Qβ coat cistron and their effect on ribosome binding☆ (1978) (84)
Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia (2003) (82)
Birth of a Prion: Spontaneous Generation Revisited (2005) (81)
Induction of type I interferon genes and interferon-inducible genes in embryonal stem cells devoid of interferon regulatory factor 1. (1993) (80)
A suspicious signature (1996) (78)
Preparation and characterization of form V DNA, the duplex DNA resulting from association of complementary, circular single-stranded DNA. (1979) (76)
B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice (2001) (74)
PrP's Double Causes Trouble (1999) (73)
Not more than 117 base pairs of 5′-flanking sequence are required for inducible expression of a human IFN-α gene (1983) (73)
Nonconsensus branch-site sequences in the in vitro splicing of transcripts of mutant rabbit beta-globin genes. (1985) (72)
Effect of interferon-alpha 1 from E. coli on some cell functions. (1980) (71)
Induction by an RNA phage of an enzyme catalyzing incorporation of ribonucleotides into ribonucleic acid. (1963) (71)
Possible mechanism for transition of viral RNA from polysome to replication complex. (1971) (69)
Bovine spongiform encephalopathy and early onset variant Creutzfeldt—Jakob disease (1997) (69)
Site-directed mutagenesis: Generation of an extracistronic mutation in bacteriophage Qβ RNA (1974) (68)
Interactions of Qβ replicase with Qβ RNA (1981) (66)
The making of a phage (1974) (65)
Structure and expression of human IFN-alpha genes. (1982) (63)
Search for a scrapie-specific nucleic acid: a progress report. (1988) (62)
Avian myeloblastosis virus RNA is terminally redundant: Implications for the mechanism of retrovirus replication (1977) (62)
Quantitative Determination and Location of Newly Synthesized Virus-Specific Ribonucleic Acid in Chicken Cells Infected with Rous Sarcoma Virus (1973) (61)
Molecular analysis of the human interferon-α gene family (1981) (60)
Molecular basis for repressor activity of Q replicase. (1972) (59)
Highly sensitive, quantitative cell-based assay for prions adsorbed to solid surfaces (2009) (58)
Transport of the murine Mx protein into the nucleus is dependent on a basic carboxy-terminal sequence. (1987) (58)
Inhibition of Qβ RNA 70S ribosome initiation complex formation by an oligonucleotide complementary to the 3′ terminal region of E. coli 16S ribosomal RNA (1978) (58)
In vitro synthesis of Rous sarcoma virus-specific RNA is catalyzed by a DNA-dependent RNA polymerase. (1974) (57)
Prions and the lymphoreticular system. (2001) (56)
Double-Stranded Ribonucleic Acid Formation in vitro by MS 2 Phage-Induced RNA Synthetase (1963) (55)
Prion Strain Discrimination Based on Rapid In Vivo Amplification and Analysis by the Cell Panel Assay (2009) (55)
Specific excision of the inserted DNA segment from hybrid plasmids constructed by the poly(dA). poly (dT) method. (1976) (55)
Post‐translational changes to PrP alter transmissible spongiform encephalopathy strain properties (2013) (55)
Molecular Biology of Prion Disease (2000) (54)
Constitutive, long-term production of human interferons by hamster cells containing multiple copies of a cloned interferon gene. (1983) (54)
Site-directed mutagenesis in DNA: generation of point mutations in cloned beta globin complementary dna at the positions corresponding to amino acids 121 to 123. (1978) (54)
Nanovariant RNAs: nucleotide sequence and interaction with bacteriophage Qbeta replicase. (1977) (53)
Assaying prions in cell culture: the standard scrapie cell assay (SSCA) and the scrapie cell assay in end point format (SCEPA). (2008) (53)
Rifampicin inhibits Focus Formation in Chick Fibroblasts infected with Rous Sarcoma Virus (1969) (53)
The role of PrP in health and disease. (2004) (52)
The 3′-termini of bacteriophage Qβ plus and minus strands (1970) (51)
Possible Origin of a Minor Virus Specific Protein (A1) in Qβ Particles (1971) (50)
Comparative antiviral efficiency of leukocyte and bacterially produced human α-interferon in rhesus monkeys (1981) (50)
The role of PrP in pathogenesis of experimental scrapie. (1996) (50)
A Novel, Quantitative Bioassay for Type I Interferon Using a Recombinant Indicator Cell Line (1990) (50)
Replication of phage RNA. (1967) (49)
Formation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coli. (1983) (48)
Genetic Informational RNA Is Not Required for Recombinant Prion Infectivity (2011) (47)
Spontaneous generation of mammalian prions (2010) (46)
Multimerization of AAGTGA and GAAAGT generates sequences that mediate virus inducibility by mimicking an interferon promoter element. (1991) (46)
Acquisition of Drug Resistance and Dependence by Prions (2013) (46)
Transgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairment. (2004) (46)
REPLICATION OF VIRAL RNA. (1964) (46)
Localization of Qβ Maturation Cistron Ribosome Binding Site (1971) (46)
Secretion of Mature IFN–α2 and Accumulation of Uncleaved Precursor by Bacillus subtilis Transformed with a Hybrid α–Amylase Signal Sequence–IFN–α2 Gene (1986) (45)
Replication of viral RNA, XVI. Enzymatic synthesis of infectious virual RNA with noninfectious Q-beta minus strands as template. (1968) (45)
Differentiation and Histological Analysis of Embryonic Stem Cell‐Derived Neural Transplants in Mice (2000) (45)
REPLICATION OF VIRAL RNA. IV. PROPERTIES OF RNA SYNTHETASE AND ENZYMATIC SYNTHESIS OF MS2 PHAGE RNA. (1964) (44)
PrP‐deficient Mice Are Resistant to Scrapie a (1994) (44)
Molecular biology of prions. (2002) (44)
Controlled transcription of a human α-interferon gene introduced into mouse L cells (1982) (42)
Is sequence conservation in interferons due to selection for functional proteins? (1985) (42)
REPLICATION OF VIRAL RNA, V. PRESENCE OF A VIRUS-SPECIFIC DOUBLE-STRANDED RNA IN LEAVES INFECTED WITH TOBACCO MOSAIC VIRUS. (1964) (42)
Perspectives: neurobiology. PrP's double causes trouble. (1999) (41)
Q replicase as repressor of Q RNA-directed protein synthesis. (1971) (40)
The 5′-flanking region of a human IFN-α gene mediates viral induction of transcription (1983) (40)
Comparisons of several biological and physicochemical properties of human leukocyte interferons produced my human leukocytes and by E. coli. (1980) (38)
The nucleotide sequence at the 5'-terminus of the Q RNA minus trand. (1970) (38)
Virus-specific proteins in Escherichia coli infected with some amber mutants of phage MS2. (1968) (38)
Molecular biology of prion diseases. (1994) (37)
Determination of viral plus and minus ribonucleic acid strands by an isotope dilution assay. (1968) (37)
Replication of viral RNA, 8. Studies on the enzymatic mechanism of replication of MS2 RNA. (1965) (36)
Transmission of prions. (2005) (36)
Replication of viral RNA. 13. The early product of phage RNA synthesis in vitro. (1967) (36)
Mutability of prions (2011) (36)
Characterization and kinetics of synthesis of 15S beta-globin RNA, a putative precursor of beta-globin mRNA. (1978) (35)
Initiation sites of Rous sarcoma virus RNA-directed DNA synthesis in vitro (1976) (35)
Spongiform encephalopathies. The prion's progress. (1991) (35)
A guanosine to adenosine transition in the 3' terminal extracistronic region of bacteriophage Q beta RNA leading to loss of infectivity. (1977) (34)
Spongiform encephalopathies: a suspicious signature. (1996) (34)
Physical mapping of Q? replicase binding sites on Q? RNA (1976) (34)
Abrogation of Complex Glycosylation by Swainsonine Results in Strain- and Cell-specific Inhibition of Prion Replication* (2011) (32)
Mutation and Selection of Prions (2012) (31)
Replication of viral ribonucleic acid. X. Turnover of virus-specific double-stranded ribonucleic acid during replication of phage MS2 in Escherichia coli. (1966) (31)
A PARTIAL GENETIC MAP OF ROUS SARCOMA VIRUS RNA: LOCATION OF POLYMERASE, ENVELOPE AND TRANSFORMATION MARKERS (1976) (31)
Partial Mapping of Ten Genes of the Human Interferon- α Family (1981) (31)
A new approach to the isolation of RNA-DNA hybrids and its application to the quantitative determination of labeled tumor virus RNA. (1974) (30)
Replication of viral RNA. XIV. Single-stranded minus strands as template for the synthesis of viral plus strands in vitro. (1967) (29)
Propagation of RML Prions in Mice Expressing PrP Devoid of GPI Anchor Leads to Formation of a Novel, Stable Prion Strain (2012) (29)
Isolation of a fraction of Bacillus megaterium DNA enriched in "minus" sequences. (1966) (27)
Transcriptional stability of cultured cells upon prion infection. (2008) (26)
Infectivity in mouse fibroblasts of polyoma DNA integrated into plasmid pBR322 or lambdoid phage DNA (1979) (26)
THE REPLICATIVE FORM OF MS2 RNA: AN X-RAY DIFFRACTION STUDY. (1964) (26)
Site-directed mutagenesis: effect of an extracistronic mutation on the in vitro propagation of bacteriophage Qbeta RNA. (1975) (26)
Sleepless in Bologna: transmission of fatal familial insomnia. (1996) (26)
Two non‐allelic human interferon alpha genes with identical coding regions. (1984) (26)
Replication of viral RNA. XI. Synthesis of viral "minus" strands in vitro. (1966) (25)
Sheep disease in human clothing (1989) (25)
Studies on the structure and synthesis of Rous sarcoma virus RNA. (1975) (24)
The prion connection: now in yeast? (1994) (24)
Presence of a putative 15S precursor to β-globin mRNA but not to α-globin mRNA in Friend cells (1977) (24)
The use of transgenic mice in the investigation of transmissible spongiform encephalopathies. (1996) (24)
Susceptibility to scrapie in mice is dependent on PrPC. (1994) (23)
Sometimes an editor makes sense (1990) (23)
Thoughts on mammalian prion strains. (2009) (23)
The Ninth Datta Lecture. Molecular biology of transmissible spongiform encephalopathies. (1996) (23)
Location of the coat cistron on the RNA of phage Q-beta. (1970) (22)
Nucleotide sequence analysis of an enzymatically synthesized RNA corresponding to the 5'-terminal region of Q beta RNA. (1969) (22)
PrP effects clarified (1996) (22)
Polyethylene sulfonate as inhibitor of initiation by Q replicase. (1972) (21)
Replication of viral RNA, VII. Further studies on the enzymatic replication of MS2 RNA. (1965) (21)
The Extended Cell Panel Assay Characterizes the Relationship of Prion Strains RML, 79A, and 139A and Reveals Conversion of 139A to 79A-Like Prions in Cell Culture (2012) (20)
REPLICATION OF VIRAL RNA. VI. NUCLEOTIDE COMPOSITION OF THE REPLICATIVE FORM OF TOBACCO MOSAIC VIRUS RNA AND OF ITS COMPONENT STRANDS. (1965) (20)
Induction of RNA Synthetase in E. coli after Infection by the RNA Phage, MS2 (1963) (20)
Yielding under the strain (1995) (19)
The chromosomal location of mouse interferon alpha genes. (1984) (19)
Escherichia coli ribosomes bind to non-initiator sites of Q beta RNA in the absence of formylmethionyl-tRNA. (1979) (18)
Modular structure of the beta‐globin and the TK promoters. (1984) (17)
Rifampicin and the replication of the RNA-containing bacteriophage Q-beta. (1970) (16)
Chromosomal location of a human alpha interferon gene family (1982) (16)
The expression of human interferon alpha genes. (1984) (15)
Reversible silencing of enhancers by sequences derived from the human IFN-alpha promoter. (1987) (15)
Resynchronization of RNA synthesis by coliphage Qbeta replicase at an internal site of the RNA template. (1973) (15)
Inhibition of Q replicase by excess template. (1972) (15)
The use of transgenic mice in the investigation of transmissible spongiform encephalopathies. (1998) (15)
Structure and expression of cloned murine IFN-alpha genes. (1983) (15)
Role of the PrP gene in transmissible spongiform encephalopathies. (1993) (15)
Role of PrP in prion diseases. (1993) (14)
A new approach to high sensitivity differential hybridization. (1986) (14)
The in vitro addition of a polyadenylate sequence to the 3' end of phage Qbeta RNA and the biological activity of the product. (1975) (13)
Site-directed mutagenesis: generation of an extracistronic mutation in bacteriophage Q beta RNA. (1974) (12)
Ethical issues in human prion diseases. (2003) (12)
Studies on Prion Replication in Spleen (2001) (12)
Reduction of possible hazards in the preparation of recombinant plasmid DNA (1976) (12)
Cloning and sequencing of the murine homologue of the human splicing factor U2AF65. (1992) (11)
Chapter 2 Molecular biology of transmissible spongiform encephalopathies (1995) (11)
Reversed genetics: a new approach to the elucidation of structure--function relationship. (1979) (11)
Molecular biology: Excision of introns in lariat form (1984) (11)
Replication of viral RNA. XV. Purification and properties of Q-beta minus strands. (1967) (10)
MODIFICATION OF THE RABBIT CHROMOSOMAL β-GLOBIN GENE BY RESTRUCTURING AND SITE-DIRECTED MUTAGENESIS (1981) (10)
A mouse to remember (2004) (10)
Molecular biology of prion diseases. (1993) (9)
EXPRESSION OF β-GLOBIN GENES MODIFIED BY RESTRUCTURING AND SITE-DIRECTED MUTAGENESIS (1981) (9)
The Use of Site-Directed Mutagenesis in Reversed Genetics (1979) (9)
Interferon regulatory factor-1 (IRF-1) activates the synthetic IRF-1-responsive sequence (GAAAGT)4 in Saccharomyces cerevisiae. (1992) (9)
Replication of Viral RNA: RNA Synthetase from Escherichia coli Infected with Phage MS2 or Qβ (1967) (8)
A Qbeta DNA-containing hybrid plasmid giving rise to Qbeta phage formation in the bacterial host [proceedings]. (1978) (8)
Cell-specific susceptibility to prion strains is a property of the intact cell (2012) (8)
Molecular genetics of transmissible spongiform encephalopathies: an introduction. (2002) (8)
7 Knockouts, Transgenics, and Transplants in Prion Research (1999) (8)
6 – SITE-DIRECTED MUTAGENESIS AS A TOOL IN GENETICS (1978) (7)
Concordance of the RNA termini of recombinants from crosses between avian retroviruses with different termini. (1978) (7)
Rabbit beta-globin mRNA production in mouse L cells transformed with cloned rabbit beta-globin chromosomal DNA. (1979) (7)
The host factor requirement of Qβ RNA replicase (1974) (7)
Synthesis in E. coli of a polypeptide with human leukocyte interferon activity. 1980. (1992) (6)
Neurotoxicity and Neuroinvasiveness of Prions (1997) (6)
Application of site-directed mutagenesis to RNA and DNA genomes. (1979) (6)
STRUCTURE AND EXPRESSION OF HUMAN IFN-α GENES (1981) (6)
EXPRESSION OF CLONED VIRAL AND CHROMOSOMAL PLASMID-LINKED DNA IN COGNATE HOST CELLS (1979) (6)
The 5'-flanking region of a human IFN-alpha gene mediates viral induction of transcription. (1983) (6)
Interactions of Q beta replicase with Q beta RNA. (1981) (6)
8 Knockouts, Knockins, Transgenics, and Transplants in Prion Research (2004) (6)
SYNTHESIS OF RABBIT β-GLOBIN-SPECIFIC RNA IN MOUSE L CELLS AND YEAST TRANSFORMED WITH CLONED RABBIT CHROMOSOMAL β-GLOBIN DNA (1979) (5)
Recombinant interferon - the 20th anniversary (2001) (5)
Revised amino acid sequence of Qbeta coat protein between positions 1 and 60. (1977) (5)
Possible origin of a minor virus specific protein (A1) in Q-beta particles. (1971) (5)
Erratum: Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells (Proceedings of the National Academy of Sciences of the United States of America (June 11, 1996) 93:12 (6158-6162)) (1996) (5)
Prion diseases. Yielding under the strain. (1995) (4)
Subunit structure of Q-beta replicase. (1970) (4)
Prion diseases (1998) (4)
A new approach to determination of the nucleotide sequence of a viral RNA (1969) (3)
The 3'-termini of bacteriophage Q-beta plus and minus strands. (1970) (3)
Monkeys are insensitive to pyrogenic effects of human α-interferons (reply) (1982) (3)
THE INITIATION SITES OF ROUS SARCOMA VIRUS RNA-DIRECTED DNA SYNTHESIS IN VITRO (1976) (2)
Corrigendum to “Transcriptional Stability of Cultured Cells upon Prion Infection” [J. Mol. Biol. 375 (2008) 1222–1233] (2009) (2)
Localization of Q-beta maturation cistron ribosome binding site. (1971) (2)
Molecular analysis of the human interferon-alpha gene family. (1981) (2)
A PHAGE IN NEW YORK (1976) (2)
Controlled transcription of a human alpha-interferon gene introduced into mouse L cells. (1982) (2)
DETERMINATION OF NUCLEOTIDE SEQUENCES IN DNA (2018) (2)
Hospital organization during multiple casualty incidents (2004) (2)
Prion protein (PrP) withamino-proximal deletions restoring susceptibility ofPrPknockout miceto (1996) (1)
The alpha interferons: some answers and many questions. (1981) (1)
Viral “Minus” Strands and the Replication of RNA Phages (1967) (1)
Application of site-directed mutagenesis to ribonucleic acid and deoxyribonucleic acid genomes. (1979) (1)
The host factor requirement of Qbeta RNA replicase. (1974) (1)
Partial mapping of ten genes of the human interferon- alpha family. (1981) (1)
Prions. Sheep disease in human clothing. (1989) (1)
RNA editing. Sometimes an editor makes sense. (1990) (1)
Evidence for the participation of a host enzyme in the activation of poly (A)-Qbeta RNA as an infectious agent. (1975) (1)
A Rapid , Sensitive , and Specific Method for the Determination of Protein in Dilute Solution 1 (0)
Mapping of the genome of Prague Rous sarcoma virus B. (1976) (0)
Target cell specificity oftwospecies ofhumaninterferon-a produced inEscherichia coli andofhybrid molecules derived fromthem (1981) (0)
MinireviewBirth of a Prion : Spontaneous Generation Revisited (2005) (0)
Procedures for the proof of prion proteins (2003) (0)
Formation of genes coding for hybrid proteins by recoinbinatlon between related, donut genes in Formtion of genes cding for hybrid proteins by fecombination between related, clooed genes in E. coli (2003) (0)
Lysogeny by f2 phage? (1978) (0)
Studies on the structure of the genome of phage Q beta. (1970) (0)
Presence of a putative 15S precursor to beta-globin mRNA but not to alpha-globin mRNA in Friend cells. (1977) (0)
A cell-based assay for mouse prions (2006) (0)
The induced transcription of a human IFN-alpha gene requires not more than 117 base pairs of 5'-flanking sequence (1983) (0)
Characterization of the interferon- and virus-inducible Mx promoter (1988) (0)
The PrP-less Mouse: A Tool for Prion Research (1993) (0)
Recombinant DNA molecules, processes for producing a polypeptide of the IFN-alfa-type and the method for selecting DNA sequences encoding polypeptides of the IFN-alfa-type (1981) (0)
Erratum: Excisions of introns in lariat form (1984) (0)
Diagnosis of transmissible spongiform encephalopathy (1997) (0)
The In Vitro Addition of a Polyadenylate Sequence to the 3' End of Phage Q0 RNA and the Biological Activity of the Product [poly(A)-Qj# RNA/phage genome adduct/terminal riboadenylate transferase/genome correction/ poly(A) inheritancel (0)
DNA Sequencer, recombinant DNA molekyler Science foerfaranden Foer framstaellning of humant of the interferon type sub-val Science of the DNA sequence. (1981) (0)
PRODUCTION OF A GLYCOSYLATED HUMAN PROTEIN BY RECOMBINANT DNA TECHNOLOGY (1983) (0)
Single-strand RNA (1989) (0)
(Recombinant DNA: a-amylase signal peptide; preprotein: antiviral activity) (1983) (0)
Science Magazine (2013) (0)
Nucleic Acids Research (2003) (0)
Transgenic nonhuman animals without prion protein (1992) (0)
Protein Structure and Biology (2013) (0)
Gene cloning by press conference. (1980) (0)
A detergent-enzyme method for effective prion decontamination of surgical steel (2005) (0)
Generation ofmicewitha 200-kbamyloid precursorprotein gene deletion byCrerecombinase-mediated site-specific recombination (1996) (0)
Japan agrees on target for climate curbs (1997) (0)
Prions: Neurotoxicity and neuroinvasion (1998) (0)
THE REPLICA TIVE FORM OF MS2 RNA: AN X-RAY DIFFRACTION STUDY* (0)
DNA ASSOCIATED WITH TOBACCO CHLOROPLASTS (1965) (0)
Constitutive factors bind to the virus responsive element of the human ifn alpha 1 gene vre alpha (1988) (0)
A process for preparing agents for the therapy of transmissible spongiform encephalopathy and non-infectious blood and tissue products, and the products produced (1997) (0)
Structure and function of phage RNA: a summary of current knowledge. (1973) (0)
Table of Contents (1995) (0)
Thechromosomal location ofmouse interferon o genes (1984) (0)
The silence of the cows (2001) (0)
THE EXPRESSION OF A CLONED RABBIT CHROMOSOMAL β-GLOBIN GENE IN MOUSE L CELLS AND YEAST (1979) (0)
T cell therapeutics for transmissible spongiform encephalopathy and method for the production of non-infectious blood products and tissues derived products (1997) (0)
CRYPTIC SPLICE SITES IN THE RABBIT ß-GLOBIN GENE ARE REVEALED FOLLOWING INACTIVATION OF AN AUTHENTIC 5′ SPLICE SITE BY MUTAGENESIS IN VITRO (1982) (0)
Subject Index, Vol. 35, 1993 (1993) (0)
Location of the Coat Cistron on the RNA of Phage Qj3 (0)
Table of Contents (1984) (0)
Recombinant DNA molecules, host cell transformation therewith, host cells containing them and process for producing a polypeptide of the IFN-alfa-type (1995) (0)
Structure–function analysis of prion protein (2001) (0)
TheInVitro Addition ofaPolyadenylate Sequence tothe3'EndofPhage Q0RNA andtheBiological Activity oftheProduct (1975) (0)
INFECTIVITY OF POLYOMA VIRUS-PLASMID pBR322 AND POLYOMA VIRUS-LAMBDA RECOMBINANTS IN MOUSE FIBROBLASTS (1979) (0)
Spontaneous Formation of Prions in Brain Tissue (2010) (0)
The Journal of Toxicological Sciences (2002) (0)
Cloning and functional expression of the influenza virus resistance gene MX (1985) (0)
THE STRUCTURE OF CLONED RABBIT AND MOUSE β-GLOBIN GENES (1979) (0)
BENEFITS AND POTENTIAL HAZARDS OP GENETIC ENGINEERING - REPORT OF A ROUND TABLE DISCUSSION (1979) (0)
Celebrated errors (1998) (0)
Modulationofneuronalactivity by target uncertainty (0)
In This Issue (2004) (0)
The Scripps Research Institute (1996) (0)
PURIFICATION OF GLOBIN mRNA AND DETECTION OF ITS PRESUMPTIVE PRECURSOR (1976) (0)
Site-directed Mutagenesis : Generation of an Extracistronic Mutation in Bacteriophage Qβ RNA (1989) (0)

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