Chen Dong

Q: What Schools Are Affiliated With Chen Dong

Chen Dong is affiliated with the following schools: Yale University, University of Science and Technology of China, MD Anderson Cancer Center, University of the Chinese Academy of Sciences, Tsinghua University, Stanford University, University of Massachusetts Medical School, Shanghai Jiao Tong University, University of Washington, Peking University, University of Alabama at Birmingham

Chen Dong's AcademicInfluence.com Rankings

Chen Dong

Computer Science

#4412

World Rank

#4647

Historical Rank

Machine Learning

#854

World Rank

#866

Historical Rank

Artificial Intelligence

#1061

World Rank

#1080

Historical Rank

Database

#1618

World Rank

#1697

Historical Rank

computer-science Degrees

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Computer Science

Chen Dong's Degrees

Masters Computer Science University of Science and Technology of China
Bachelors Computer Science University of Science and Technology of China

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Chen Dong's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 (2005) (4461)
MAP kinases in the immune response. (2002) (1702)
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells (2007) (1588)
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. (2008) (1585)
STAT3 Regulates Cytokine-mediated Generation of Inflammatory Helper T Cells* (2007) (1421)
Bcl6 Mediates the Development of T Follicular Helper Cells (2009) (1375)
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. (2008) (1170)
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. (2008) (1155)
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. (2009) (1131)
TH17 cells in development: an updated view of their molecular identity and genetic programming (2008) (1085)
ICOS co-stimulatory receptor is essential for T-cell activation and function (2001) (979)
Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals (2020) (897)
Regulation of inflammatory responses by IL-17F (2008) (779)
T helper 17 cells promote cytotoxic T cell activation in tumor immunity. (2009) (726)
Defective T cell differentiation in the absence of Jnk1. (1998) (665)
IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC–activated Th2 memory cells (2007) (654)
Interleukin 25 promotes the initiation of proallergic type 2 responses (2007) (564)
Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cells (2006) (508)
IL-17 cytokines in immunity and inflammation (2013) (498)
Follicular regulatory T (Tfr) cells with dual Foxp3 and Bcl6 expression suppress germinal center reactions (2011) (489)
CCR6 Regulates the Migration of Inflammatory and Regulatory T Cells1 (2008) (471)
B7S1, a novel B7 family member that negatively regulates T cell activation. (2003) (417)
ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity (2008) (398)
A critical role of neural-specific JNK3 for ischemic apoptosis (2003) (398)
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens (2007) (398)
MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines. (2001) (383)
Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells (2009) (367)
JNK is required for effector T-cell function but not for T-cell activation (2000) (357)
Act1 Adaptor Protein Is an Immediate and Essential Signaling Component of Interleukin-17 Receptor* (2006) (351)
Toll-like receptor 2 signaling in CD4(+) T lymphocytes promotes T helper 17 responses and regulates the pathogenesis of autoimmune disease. (2010) (302)
Murine B7-H3 Is a Negative Regulator of T Cells1 (2004) (302)
Chromatin Remodeling of Interleukin-17 (IL-17)-IL-17F Cytokine Gene Locus during Inflammatory Helper T Cell Differentiation* (2007) (289)
Defective Antigen Processing in GILT-Free Mice (2001) (259)
Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages (DOI: 10.1016/j.immuni.2008.05.009) (2008) (258)
Characterization of Mouse and Human B7-H3 Genes1 (2002) (257)
Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5 (2004) (255)
The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells. (2015) (251)
T helper 17 cells play a critical pathogenic role in lung cancer (2014) (249)
Expression and regulation of IL-22 in the IL-17-producing CD4+ T lymphocytes (2006) (241)
Cutting Edge: Critical Role of Inducible Costimulator in Germinal Center Reactions1 (2001) (239)
Transcription factor Achaete-Scute homologue 2 initiates T follicular helper cell development (2014) (239)
T‐cell tolerance or function is determined by combinatorial costimulatory signals (2006) (238)
B7‐H3 is a potent inhibitor of human T‐cell activation: No evidence for B7‐H3 and TREML2 interaction (2009) (234)
IL-17 family member cytokines: regulation and function in innate immunity. (2010) (232)
Bcl6 expression specifies the T follicular helper cell program in vivo (2012) (226)
A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses (2007) (225)
Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction (2019) (223)
MAP kinases in immune responses. (2005) (221)
Regulation of IL-9 expression by IL-25 signaling (2010) (219)
Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E. (2011) (217)
STAT5 Protein Negatively Regulates T Follicular Helper (Tfh) Cell Generation and Function* (2012) (210)
TL1A–DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease (2008) (208)
Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function (2017) (207)
Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation (2012) (200)
Signaling of interleukin-17 family cytokines in immunity and inflammation. (2011) (194)
Regulation and Function of Proinflammatory TH17 Cells (2008) (189)
Impairment of T and B Cell Development by Treatment with a Type I Interferon (1998) (188)
Ursolic Acid Suppresses Interleukin-17 (IL-17) Production by Selectively Antagonizing the Function of RORγt Protein* (2011) (186)
Regulatory mechanisms of mitogen-activated kinase signaling (2007) (184)
BTNL2, a Butyrophilin-Like Molecule That Functions to Inhibit T Cell Activation1 (2006) (183)
Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation (2012) (175)
Th1 and Th2 cells. (2001) (174)
Vitamin D Suppresses Th17 Cytokine Production by Inducing C/EBP Homologous Protein (CHOP) Expression* (2010) (174)
Regulation of T cell activation and tolerance by PDL2. (2006) (168)
Transcriptional regulation of th2 differentiation by inducible costimulator. (2003) (166)
STAT 3 Regulates Cytokine-mediated Generation of Inflammatory Helper T Cells * (2007) (164)
IL-17A produced by γδ T cells promotes tumor growth in hepatocellular carcinoma. (2014) (164)
IL-17F: regulation, signaling and function in inflammation. (2009) (153)
New B7 Family Checkpoints in Human Cancers (2017) (150)
Cigarette Smoke Induction of Osteopontin (SPP1) Mediates TH17 Inflammation in Human and Experimental Emphysema (2012) (149)
Negative regulation of IL-17-mediated signaling and inflammation by ubiquitin-specific protease 25 (2012) (148)
Deficiency in T follicular regulatory cells promotes autoimmunity (2018) (147)
NK Cell Deficiency Predisposes to Viral-Induced Th2-Type Allergic Inflammation via Epithelial-Derived IL-25 (2010) (147)
Transcriptional regulation of follicular T‐helper (Tfh) cells (2013) (144)
CD11b+ Monocytes Abrogate Th17 CD4+ T Cell-Mediated Experimental Autoimmune Myocarditis1 (2008) (144)
Yin–Yang of costimulation: crucial controls of immune tolerance and function (2009) (143)
Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease. (2011) (142)
Cutting Edge: Programed Death (PD) Ligand-1/PD-1 Interaction Is Required for CD8+ T Cell Tolerance to Tissue Antigens1 (2006) (140)
The MicroRNA-183-96-182 Cluster Promotes T Helper 17 Cell Pathogenicity by Negatively Regulating Transcription Factor Foxo1 Expression. (2016) (134)
B7h is required for T cell activation, differentiation, and effector function (2003) (133)
A Protective Role by Interleukin-17F in Colon Tumorigenesis (2012) (131)
Regulation and pro‐inflammatory function of interleukin‐17 family cytokines (2008) (131)
Cell fate decision: T-helper 1 and 2 subsets in immune responses (2000) (131)
Co‐inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor‐Infiltrating Myeloid Cells Induces Dysfunction of Anti‐tumor CD8+ T Cells (2018) (127)
The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation. (2010) (126)
Aberrant Regulation of Synovial T Cell Activation by Soluble Costimulatory Molecules in Rheumatoid Arthritis1 (2006) (125)
CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-κB activation (2007) (124)
Toll-like receptor regulation of effector T lymphocyte function. (2013) (123)
Differential involvement of p38 mitogen‐activated protein kinase kinases MKK3 and MKK6 in T‐cell apoptosis (2002) (120)
New checkpoints in cancer immunotherapy (2017) (113)
The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation (2013) (113)
Melatonin reduces memory changes and neural oxidative damage in mice treated with D‐galactose (2002) (113)
Melanoma cells express ICOS ligand to promote the activation and expansion of T-regulatory cells. (2010) (112)
Transcription of Il17 and Il17f is controlled by conserved noncoding sequence 2. (2012) (111)
IL-21 regulates Th17 cells in rheumatoid arthritis. (2010) (110)
IL-25 and CD4(+) TH2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy. (2016) (107)
Interleukin-17B Antagonizes Interleukin-25-Mediated Mucosal Inflammation. (2015) (104)
Inducible costimulator is essential for collagen-induced arthritis. (2003) (103)
Mechanical Skin Injury Promotes Food Anaphylaxis by Driving Intestinal Mast Cell Expansion. (2019) (101)
SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation. (2012) (100)
Cutting Edge: In Vitro Generated Th17 Cells Maintain Their Cytokine Expression Program in Normal but Not Lymphopenic Hosts1 (2009) (100)
Highlights of 10 years of immunology in Nature Reviews Immunology (2011) (99)
Genome-wide Analysis Identifies Bcl6-Controlled Regulatory Networks during T Follicular Helper Cell Differentiation. (2016) (97)
Smad2 Positively Regulates the Generation of Th17 Cells* (2010) (97)
Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors. (2018) (97)
Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment (2009) (96)
Regulation of immune and autoimmune responses by ICOS. (2003) (96)
Cytokine Regulation and Function in T Cells. (2021) (94)
Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. (2003) (94)
High Levels of Eomes Promote Exhaustion of Anti-tumor CD8+ T Cells (2018) (94)
Cutting Edge: Regulation of Intestinal Inflammation and Barrier Function by IL-17C (2012) (93)
Cholesterol negatively regulates IL-9–producing CD8+ T cell differentiation and antitumor activity (2018) (92)
Generation of RORγt+ Antigen-Specific T Regulatory 17 Cells from Foxp3+ Precursors in Autoimmunity. (2017) (91)
Therapeutic antibodies that target inflammatory cytokines in autoimmune diseases. (2016) (90)
USP18 inhibits NF-κB and NFAT activation during Th17 differentiation by deubiquitinating the TAK1–TAB1 complex (2013) (89)
An Interleukin‐25‐Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin Inflammation (2018) (89)
Ubiquitin-Specific Protease 25 Regulates TLR4-Dependent Innate Immune Responses Through Deubiquitination of the Adaptor Protein TRAF3 (2013) (87)
Smad3 Differentially Regulates the Induction of Regulatory and Inflammatory T Cell Differentiation* (2009) (86)
Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6 (2015) (85)
The IL-17/IL-23 axis of inflammation in cancer: friend or foe? (2009) (82)
Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis (2016) (82)
JNK1 Is Required for T Cell-Mediated Immunity Against Leishmania major Infection1 (2000) (81)
Interleukin-17 receptor D constitutes an alternative receptor for interleukin-17A important in psoriasis-like skin inflammation (2019) (80)
Cross Talk between Follicular Th Cells and Tumor Cells in Human Follicular Lymphoma Promotes Immune Evasion in the Tumor Microenvironment (2013) (80)
Innate signals from Nod2 block respiratory tolerance and program T(H)2-driven allergic inflammation. (2010) (78)
IL-23 signaling enhances Th2 polarization and regulates allergic airway inflammation (2009) (78)
Molecular mechanisms of T‐cell tolerance (2011) (76)
The Transcription Factor Tox2 Drives T Follicular Helper Cell Development via Regulating Chromatin Accessibility. (2019) (76)
Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4+Foxp3+ regulatory T cells in the establishment of oral tolerance. (2010) (76)
Signaling by the JNK Group of MAP Kinases (2001) (75)
An NKT-mediated autologous vaccine generates CD4 T-cell dependent potent antilymphoma immunity. (2007) (74)
Interleukin-25 (IL-25) Promotes Efficient Protective Immunity against Trichinella spiralis Infection by Enhancing the Antigen-Specific IL-9 Response (2013) (73)
IL‐25 in allergic inflammation (2017) (72)
Protease Allergens Induce the Expression of IL-25 via Erk and p38 MAPK Pathway (2010) (72)
Cutting Edge: Smad2 and Smad4 Regulate TGF-β–Mediated Il9 Gene Expression via EZH2 Displacement (2013) (72)
CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-{kappa}B activation. (2007) (71)
Expression of the inhibitory B7 family molecule VISTA in human colorectal carcinoma tumors (2018) (71)
MKP-1 Is Necessary for T Cell Activation and Function* (2009) (70)
Structure and function of interleukin-17 family cytokines (2011) (69)
JNK1 negatively controls anti-fungal innate immunity by suppressing CD23 expression (2017) (65)
The protective effects of melatonin from oxidative damage induced by amyloid beta‐peptide 25–35 in middle‐aged rats (2002) (64)
A complex issue on CD4+ T‐cell subsets (2013) (63)
A Novel NF-κB Binding Site Controls Human Granzyme B Gene Transcription1 (2006) (61)
Improved regenerative myogenesis and muscular dystrophy in mice lacking Mkp5. (2013) (61)
Differentiation and function of pro-inflammatory Th17 cells. (2009) (60)
Genetic controls of Th17 cell differentiation and plasticity (2011) (59)
Cutting Edge: Generation of Colitogenic Th17 CD4 T Cells Is Enhanced by IL-17+ γδ T Cells (2011) (58)
Protective effect of melatonin against liver injury in mice induced by Bacillus Calmette-Guerin plus lipopolysaccharide. (2004) (57)
A non‐redundant role for MKP5 in limiting ROS production and preventing LPS‐induced vascular injury (2009) (54)
XCL1 Enhances Regulatory Activities of CD4+CD25highCD127low/− T Cells in Human Allergic Asthma1 (2008) (53)
Cutting Edge: A Critical Role of B and T Lymphocyte Attenuator in Peripheral T Cell Tolerance Induction 1 (2009) (52)
Local triggering of the ICOS coreceptor by CD11c(+) myeloid cells drives organ inflammation in lupus. (2015) (52)
A Butyrophilin Family Member Critically Inhibits T Cell Activation (2010) (51)
ICOS Mediates the Development of Insulin-Dependent Diabetes Mellitus in Nonobese Diabetic Mice1 (2008) (50)
Tumor-expressed B7-H3 mediates the inhibition of antitumor T-cell functions in ovarian cancer insensitive to PD-1 blockade therapy (2019) (50)
Map kinase phosphatase 5 protects against sepsis-induced acute lung injury. (2012) (49)
Immune regulation by novel costimulatory molecules (2003) (49)
ICOS Controls Effector Function but Not Trafficking Receptor Expression of Kidney-Infiltrating Effector T Cells in Murine Lupus1 (2009) (48)
Divergent Roles for Airway Epithelial MMP7 and Retinoic Acid in Experimental Asthma (2009) (47)
Bone loss and aggravated autoimmune arthritis in HLA-DRβ1-bearing humanized mice following oral challenge with Porphyromonas gingivalis (2016) (47)
ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation (2020) (47)
A novel NF-kappaB binding site controls human granzyme B gene transcription. (2006) (46)
Control of T Helper Cell Differentiation--in Search of Master Genes (2000) (46)
NCR− group 3 innate lymphoid cells orchestrate IL-23/IL-17 axis to promote hepatocellular carcinoma development (2019) (46)
Protein SUMOylation Is Required for Regulatory T Cell Expansion and Function. (2016) (43)
Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28 (2018) (43)
IL-17C is required for lethal inflammation during systemic fungal infection (2015) (43)
Febrile Temperature Critically Controls the Differentiation and Pathogenicity of T Helper 17 Cells. (2020) (43)
Positive Signaling Through CD72 Induces Mitogen-Activated Protein Kinase Activation and Synergizes with B Cell Receptor Signals to Induce X-Linked Immunodeficiency B Cell Proliferation1 (2001) (43)
IL-9-producing T cells: potential players in allergy and cancer (2020) (42)
ICOS is essential for the development of experimental autoimmune myasthenia gravis (2004) (42)
Abundant c-Fas-associated death domain-like interleukin-1-converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell death. (2009) (41)
ICOS cooperates with CD28, IL‐2, and IFN‐γ and modulates activation of human naïve CD4+ T cells (2006) (40)
Regulatory mechanisms of helper T cell differentiation: new lessons learned from interleukin 17 family cytokines. (2008) (39)
Intrahepatic Innate Lymphoid Cells Secrete IL-17A and IL-17F That Are Crucial for T Cell Priming in Viral Infection (2014) (38)
A Costimulation-Initiated Signaling Pathway Regulates NFATc1 Transcription in T Lymphocytes1 (2007) (37)
Trim33 mediates the proinflammatory function of Th17 cells (2018) (37)
The Microbiome Activates CD4 T-cell–mediated Immunity to Compensate for Increased Intestinal Permeability (2017) (37)
CCR 6 Regulates the Migration of Inflammatory and Regulatory T Cells 1 (2008) (36)
Dual Protective Mechanisms of Matrix Metalloproteinases 2 and 9 in Immune Defense against Streptococcus pneumoniae (2011) (36)
Regulatory immune responses induced by IL-1 receptor antagonist in rheumatoid arthritis. (2011) (36)
HDAC2 Suppresses IL17A‐Mediated Airway Remodeling in Human and Experimental Modeling of COPD (2017) (35)
IL-23/IL-17 Biology and Therapeutic Considerations (2008) (34)
Deletion of TAK1 in the Myeloid Lineage Results in the Spontaneous Development of Myelomonocytic Leukemia in Mice (2012) (33)
Epicutaneous Exposure to Staphylococcal Superantigen Enterotoxin B Enhances Allergic Lung Inflammation via an IL-17A Dependent Mechanism (2012) (33)
Opposing effects of ICOS on graft-versus-host disease mediated by CD4 and CD8 T cells. (2006) (31)
DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis (2016) (31)
MAPK Phosphatase 5 Expression Induced by Influenza and Other RNA Virus Infection Negatively Regulates IRF3 Activation and Type I Interferon Response. (2015) (31)
Role of Cyclooxygenase-2 Pathway in Creating an Immunosuppressive Microenvironment and in Initiation and Progression of Wilms' Tumor (2017) (31)
Novel Function of IFN-γ: Negative Regulation of Dendritic Cell Migration and T Cell Priming1 (2006) (30)
IL-25 blockade inhibits metastasis in breast cancer (2016) (30)
Inhibitory costimulation and anti-tumor immunity. (2007) (29)
Concomitant suppression of TH2 and TH17 cell responses in allergic asthma by targeting retinoic acid receptor–related orphan receptor &ggr;t (2017) (29)
B 7-H 3 is a potent inhibitor of human T cell activation : No evidence for B 7-H 3 and TREML 2 interaction (2012) (29)
CXCR5+CD8+ T cells are a distinct functional subset with antitumor activity (2019) (29)
Inducible costimulator is essential for collagen-induced arthritis. (2003) (29)
Extracellular matrix protein 1 promotes follicular helper T cell differentiation and antibody production (2018) (28)
Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93. (2021) (27)
ICOS cooperates with CD28, IL-2, and IFN-gamma and modulates activation of human naïve CD4+ T cells. (2006) (27)
CD4+ICOS+ T lymphocytes inhibit T cell activation 'in vitro' and attenuate autoimmune encephalitis 'in vivo'. (2008) (27)
The CD70-CD27 axis, a new brake in the T helper 17 cell response. (2013) (27)
Analysis of VISTA expression and function in renal cell carcinoma highlights VISTA as a potential target for immunotherapy (2019) (27)
MEKK3 Regulates IFN-γ Production in T Cells through the Rac1/2-Dependent MAPK Cascades (2011) (27)
Targeting Th17 cells in immune diseases (2014) (26)
A Critical Role of Costimulation during Intrathymic Development of Invariant NK T Cells1 (2008) (26)
Opposing Effects of ICOS on Graft-versus-Host Disease Mediated by CD4 and CD8 T Cells1 (2006) (25)
The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation. (2020) (24)
Improvement of melatonin to the learning and memory impairment induced by amyloid beta-peptide 25 - 35 in elder rats. (2001) (24)
SOSTDC1-producing follicular helper T cells promote regulatory follicular T cell differentiation (2020) (24)
Trisomy 21–induced dysregulation of microglial homeostasis in Alzheimer’s brains is mediated by USP25 (2021) (24)
Cyclic AMP-Responsive Element-Binding Protein (CREB) is Critical in Autoimmunity by Promoting Th17 but Inhibiting Treg Cell Differentiation (2017) (23)
Roles of Myeloid and Lymphoid Cells in the Pathogenesis of Chronic Obstructive Pulmonary Disease (2018) (23)
Immune checkpoint receptors in cancer: redundant by design? (2017) (22)
Characterization of B7S3 as a Novel Negative Regulator of T Cells1 (2007) (22)
BATF: bringing (in) another Th17-regulating factor. (2009) (21)
Critical regulation of early Th17 cell differentiation by IL-1 signaling (48.24) (2009) (20)
MAPK Phosphatase 7 Regulates T Cell Differentiation via Inhibiting ERK-Mediated IL-2 Expression (2015) (20)
Regulation of Pathogenic T Helper 17 Cell Differentiation by Steroid Receptor Coactivator-3. (2018) (20)
CCAAT/Enhancer-Binding Protein α Negatively Regulates IFN-γ Expression in T Cells (2014) (20)
112 Essential Autocrine Regulation by IL-21 in the Generation of Inflammatory T Cells (2007) (20)
IL-17C/IL-17RE Augments T Cell Function in Autoimmune Hepatitis (2017) (19)
The T-Cell Inhibitory Molecule Butyrophilin-Like 2 Is Up-regulated in Mild Plasmodium falciparum Infection and Is Protective During Experimental Cerebral Malaria. (2015) (19)
The Transcription Factor E74-like Factor 4 Suppresses Differentiation of Proliferating CD4+ T Cells to the Th17 Lineage (2014) (19)
Protective Function of Mitogen‐Activated Protein Kinase Phosphatase 5 in Aging‐ and Diet‐Induced Hepatic Steatosis and Steatohepatitis (2019) (18)
Ubc9 Is Required for Positive Selection and Late-Stage Maturation of Thymocytes (2017) (18)
The role of miR-183 cluster in immunity. (2019) (18)
Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1. (2019) (18)
The deubiquitinase USP25 supports colonic inflammation and bacterial infection and promotes colorectal cancer (2020) (18)
Adoptively transferred donor IL-17-producing CD4+ T cells augment, but IL-17 alleviates, acute graft-versus-host disease (2016) (17)
Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAPK Phosphatase 5* (2015) (17)
Don't leave home without it: the IL-23 visa to TH-17 cells (2009) (17)
New battlefields for costimulation (2006) (17)
Novel function of IFN-gamma: negative regulation of dendritic cell migration and T cell priming. (2006) (16)
Mouse Th17 cells: Current understanding of their generation and regulation (2009) (16)
Epstein Barr Virus-Induced 3 (EBI3) Together with IL-12 Negatively Regulates T Helper 17-Mediated Immunity to Listeria monocytogenes Infection (2013) (16)
Interleukin‐17A deficiency ameliorates streptozotocin‐induced diabetes (2015) (15)
B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema (2018) (15)
An essential function for MKP5 in the formation of oxidized low density lipid-induced foam cells. (2012) (14)
Regulation of T cell activation and tolerance by PDL 2 (2006) (14)
Signaling and cell death in lymphocytes (2007) (14)
Ginkgolide B protects against cognitive impairment in senescence-accelerated P8 mice by mitigating oxidative stress, inflammation and ferroptosis. (2021) (13)
MAPK Phosphotase 5 Deficiency Contributes to Protection against Blood-Stage Plasmodium yoelii 17XL Infection in Mice (2014) (12)
Identification of core functional region of murine IL-4 using peptide phage display and molecular modeling. (2006) (12)
Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation. (2021) (11)
Measurement of Interleukin‐17 (2001) (11)
Helper T Cells and Cancer-Associated Inflammation: A New Direction for Immunotherapy? (2017) (11)
Keeping autoimmunity in check: how to control a Th17 cell controller. (2008) (10)
Type 17 immunity promotes the exhaustion of CD8+ T cells in cancer (2021) (10)
Targeting lysophospholipid acid receptor 1 and ROCK kinases promotes antiviral innate immunity (2021) (9)
New territory for T follicular helper cells. (2013) (9)
CISH controls bacterial burden early after infection with Mycobacterium tuberculosis in mice. (2017) (8)
T Follicular Helper Cells Regulate Humoral Response for Host Protection against Intestinal Citrobacter rodentium Infection (2020) (8)
Activation of the Transcription Factor c-Maf in T Cells Is Dependent on the CARMA1-IKKβ Signaling Cascade (2013) (7)
USP25 inhibition ameliorates Alzheimer’s pathology through the regulation of APP processing and Aβ generation (2022) (7)
Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality. (2019) (7)
Helper T-cell heterogeneity: a complex developmental issue in the immune system (2010) (7)
RORα is critical for mTORC1 activity in T cell-mediated colitis. (2021) (7)
Treg-expression of CIS suppresses allergic airway inflammation through antagonizing an autonomous TH2 program (2019) (7)
Molecular mechanisms of T helper 17 cell differentiation: Emerging roles for transcription cofactors. (2019) (6)
T H 17 Cytokines: Characteristics, Regulation, and Biological Function (2011) (6)
High stearic acid diet modulates gut microbiota and aggravates acute graft-versus-host disease (2021) (6)
Correction: A Critical Role of Costimulation during Intrathymic Development of Invariant NK T Cells. (2020) (5)
Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies (2014) (5)
Interleukin-17 Family (2016) (5)
(IL‐)12 and 21: a new kind of help in the follicles (2009) (5)
Microenvironment and Immunology IL-17 A Produced by gd T Cells Promotes Tumor Growth in Hepatocellular Carcinoma (2014) (4)
Erratum: Inducible costimulator is essential for collagen-induced arthritis (Journal of Clinical Investigation (2003) 111 (701-706)) (2003) (4)
Pathogen-associated T follicular helper cell plasticity is critical in anti-viral immunity (2022) (4)
A shedding soluble form of interleukin-17 receptor D exacerbates collagen-induced arthritis through facilitating TNF-α-dependent receptor clustering (2020) (4)
IL-17C Mitigates Murine Acute Graft-vs.-Host Disease by Promoting Intestinal Barrier Functions and Treg Differentiation (2018) (4)
Defining the TH17 cell lineage (2021) (4)
T cells and T cell tumors efficiently generate antigen-specific cytotoxic T cell immunity when modified with an NKT ligand (2012) (3)
Nobel goes to immune checkpoint—Innovative cancer treatment by immunotherapy (2018) (3)
The advancement of immunotherapy in hepatocellular carcinoma (2020) (3)
CCAAT/Enhancer-Binding Protein a Negatively Regulates IFN-g Expression in T Cells (2014) (3)
IL-25 and CD4 + T H 2 cells enhance ILC2-derived IL-13 production that promotes IgE-mediated experimental food allergy (2016) (3)
CCAAT/Enhancer-Binding Protein alpha Negatively Regulates IFN-gamma Expression in T Cells (2014) (3)
The Role Of Il-25 In Airway Allergic Response (2007) (3)
MAP kinase phosphatase 1 is necessary for T cell activation and function (35.1) (2009) (2)
Zooming on T cells in cancer (2022) (2)
DePICting T cell–APC crosstalk in cancer (2022) (2)
212: MAP kinase phosphatase 5 expression induced by influenza virus infection negatively regulates IRF3 activation and type I interferon response (2014) (2)
RORγt expression in mature TH17 cells safeguards their lineage specification by inhibiting conversion to TH2 cells (2022) (2)
5 IL-25 Promotes the Initiation of Pro-allergic Type 2 Responses (2007) (2)
Seventeen on inflammation (2020) (2)
SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8+ T cell cytotoxic function (2022) (2)
Abstract 3317: Discovery of novel STING agonists with robust anti-tumor activity (2020) (2)
Donor γδT Cells Promote GVL Effect and Mitigate aGVHD in Allogeneic Hematopoietic Stem Cell Transplantation (2020) (2)
c-Jun NH2-terminal kinase (JNK)/stress-activated protein kinase-associated protein 1 is a critical regulator for arthritis progression by meditating inflammation in mice model. (2020) (2)
Transcription factor Ascl2 promotes germinal center B cell responses by directly regulating AID transcription. (2021) (1)
Co-stimulation Regulation of Immune Tolerance and Autoimmunity (2007) (1)
Requirement of MMP2 and MMP9 for lung innate immune defense against Streptococcus pneumoniae infection (37.34) (2010) (1)
Adapting to the world: The determination and plasticity of T follicular helper cells. (2022) (1)
STAT3 regulates CD8+ T cell differentiation and functions in cancer and acute infection. (2023) (1)
PD-1+ T Cell Subsets in Follicular Lymphoma Tumor Microenvironment and Their Implications for Prognosis and Therapy (2011) (1)
184: DUSP11 is a critical regulator of innate immune responses mediated by dendritic cells (2013) (1)
Gene regulation and function: its rocking science. (2005) (1)
IL-25 blockade inhibits metastasis in breast cancer (2016) (1)
Erratum to The Methylcytosine Dioxygenase Tet2 Promotes DNA Demethylation and Activation of Cytokine Gene Expression in T Cells (Immunity 42, 613-626, 2015) (2015) (1)
SY-14 Cytokine regulation of Th17 and Tfh cell differentiation (2008) (1)
Regulation of TLR-triggered innate immune response by ubiquitin-specific protease 25 (180.8) (2012) (1)
Targeting the immune system: a new horizon of cancer therapies (2015) (1)
AKT2 reduces IFNβ1 production to modulate antiviral responses and systemic lupus erythematosus (2022) (1)
TH17 Cytokines: Characteristics, Regulation, and Biological Function (2020) (1)
IL-17D-induced inhibition of DDX5 expression in keratinocytes amplifies IL-36R-mediated skin inflammation (2022) (1)
PS3-41 IL-27 is a dominant negative immunoregulator during Listeria Mongytogenes infection (2010) (1)
CIS inhibits Treg-intrinsic TH2 program and suppresses allergic airway inflammation (2019) (0)
Cytokine receptors and signaling (WS-089) Chairpersons: Tetsuji Naka, Warren Leonard (2010) (0)
Running Title: The role of IL-25 during T. spiralis infection (2013) (0)
STAT5 controls Tfh development (2012) (0)
Antigen-Specific IL-9 Response spiralis Infection by Enhancing the Protective Immunity against Trichinella Interleukin-25 (IL-25) Promotes Efficient (2014) (0)
CD 8 T Cells Graft-versus-Host Disease Mediated by CD 4 Opposing Effects of ICOS on Claudio Anasetti (2006) (0)
CellsIntrathymic Development of Invariant NK T A Critical Role of Costimulation during (2008) (0)
Dec2 regulates initial TH2 lineage commitment (99.12) (2010) (0)
Erratum to: Signaling and cell death in lymphocytes (2012) (0)
Tumor-expressed B7-H3 mediates the inhibition of antitumor T-cell functions in ovarian cancer insensitive to PD-1 blockade therapy (2019) (0)
MAP kinase phosphatase 5 regulates innate immune response to influenza via type I interferon (108.14) (2012) (0)
Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28 (2018) (0)
Expression and regulation of IL-22 in the IL-17-producing CD4+ T lymphocytes (B46) (2007) (0)
PL1-1 Regulation and function of IL-17 family cytokines in inflammatory responses (2010) (0)
Corrigendum to ‘Cyclic AMP-Responsive element-binding protein (CREB) is critical in autoimmunity by promoting Th17 but inhibiting treg cell differentiation’ (2020) (0)
A critical role of GRAIL in T cell activation and tolerance (50.18) (2010) (0)
Evolution of RAG transposon unveiled (2016) (0)
DUSP11 is required for innate immunity (167.4) (2012) (0)
Correction for Lin et al., Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6 (2020) (0)
Molecules in Rheumatoid Arthritis Activation by Soluble Costimulatory Aberrant Regulation of Synovial T Cell (2006) (0)
Correction: CCAAT/Enhancer-Binding Protein α Negatively Regulates IFN-γ Expression in T Cells (2020) (0)
Abstract B43: Targeting tumor microenvironment for treatment of K-ras mutant lung cancer (2014) (0)
Transcriptional regulation of helper T cell specification (2010) (0)
Co-stimulatory regulation of Th-cell differentiation and function Th-cell activation requires two signals: the first through recognition of antigen peptide–MHC complexes by the T-cell receptors (TcR) and the second via co-stimula- (0)
Author Correction: Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment (2020) (0)
STAT5 controls Tfh development (121.19) (2012) (0)
Murine Lupus Kidney-Infiltrating Effector T Cells in Trafficking Receptor Expression of ICOS Controls Effector Function but Not (2009) (0)
Lasker takes two—Discoveries were honored for defining major components of our lymphoid system (2019) (0)
Immune response regulated by CD3/Crry co-stimulation on CD4~+T cells in mice (2010) (0)
IL-25 mediates the induction of IL-9-producing T cell responses against T. spiralis infection (43.20) (2012) (0)
Science Signaling Podcast: 14 May 2013 (2013) (0)
IL-25, another promoter of allergy (2009) (0)
Developmental requirements of T follicular helper cells (90.10) (2009) (0)
P-207 The Role of IL-17C and IL-17RE in the Development of Inflammatory Bowel Disease (2013) (0)
Cytokine receptors and signaling (PP-089) Chairperson: Tetsuji Naka (2010) (0)
Abstract A32: Mechanistic Dissection of Lung Cancer Promotion by Airway Inflammation (2012) (0)
C-FLIP Expression Determines Low Sensitivity Of Type 17 T Helper Cells To Activation-Induced Cell Death (2009) (0)
Tolerance Induction Lymphocyte Attenuator in Peripheral T Cell Cutting Edge: A Critical Role of B and T (2009) (0)
Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction (2019) (0)
IL-2 Expression Differentiation via Inhibiting ERK-Mediated MAPK Phosphatase 7 Regulates T Cell (2015) (0)
Infection Leishmania major Immunity Against JNK 1 Is Required for T Cell-Mediated (2000) (0)
IL-17C inhibits the development of hepatocellular carcinoma through the modulation of gut microbiota (2018) (0)
A cis-element at the Rorc locus regulates the development of type 3 innate lymphoid cells (2023) (0)
Hepatocellular Carcinoma T Cells Promotes Tumor Growth in δγ IL-17 A Produced (2014) (0)
Dec2 regulates initial TH2 lineage commitment (2010) (0)
T Cells to the Th17 Lineage + CD4Suppresses Differentiation of Proliferating The Transcription Factor E74-Like Factor 4 (2013) (0)
The FoxO4/DKK3 axis represses IFN-γ expression by Th1 cells and limits antimicrobial immunity (2022) (0)
Innate and adaptive immune abnormalities underlying autoimmune diseases: the genetic connections (2023) (0)
Erratum: Gene regulation and function: It's rocking science (Immunity (December 2005) 23 (557-560)) (2006) (0)
CIS inhibits effector programs in regulatory T cells (IRM15P.459) (2015) (0)
An Essential Role For T Helper 17 (Th17) Immune Response In Lung Cancer Promotion By Inflammation (2012) (0)
Co-inhibitory Molecule B 7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD 8 + T Cells Graphical (2018) (0)
IL-17C ameliorates murine acute graft-versus-host disease by promoting regulatory T cell differentiation and maintaining intestinal epithelial barrier functions (2017) (0)
MicroenvironmentPromotes Immune Evasion in the Tumor Lymphoma Tumor Cells in Human Follicular Cross Talk between Follicular Th Cells and (2013) (0)
A critical role of BTLA in peripheral T cell tolerance induction (48.18) (2009) (0)
Amendment history : Retraction ( November 2003 ) Inducible costimulator is essential for collagen-induced arthritis (2018) (0)
Erratum to: Signaling and cell death in lymphocytes (2012) (0)
Bone loss in HLA-DRβ1-bearing humanized mice following oral challenge with Porphyromonas gingivalis (2016) (0)
[Nonsteroid anti-inflammatory agents and shock]. (1988) (0)
Regulation of naïve T cell tolerance and regulatory T cell function by GRAIL (113.21) (2011) (0)
Beyond interleukin-17-targeted therapy: Complexity of environment-genetics-immunology needs to be addressed (2022) (0)
Nobel goes to immune checkpoint—Innovative cancer treatment by immunotherapy (2018) (0)
T Cell Tolerance to Tissue Antigens + CD8Ligand-1/PD-1 Interaction Is Required for Cutting Edge: Programed Death (PD) (2006) (0)
Costimulator in Germinal Center Reactions Cutting Edge: Critical Role of Inducible (2001) (0)
Current Status of Immunotherapy for Metastatic Colorectal Cancer (2020) (0)
The effects of PHGF and cytokines on fibroblast proliferation (1996) (0)
Peripheral tolerance and lymphocyte anergy (PP-072) (2010) (0)
Cell Priming in Viral Infection IL-17A and IL-17F That Are Crucial for T Intrahepatic Innate Lymphoid Cells Secrete (2014) (0)
Abstracts from the 4th ImmunoTherapy of Cancer Conference (2017) (0)
the arise of new therapies in cancers (2014) (0)
Cell autonomous expression of BCL6 is required to maintain lineage identity of mouse CCR6+ ILC3s. (2023) (0)
Treg expression of CIS suppresses allergic airway inflammation through antagonizing an autonomous TH2 program (2019) (0)
DUSP11 is required for innate immunity (2012) (0)
IL-17 cytokine family and receptors (2012) (0)
Streptococcus pneumoniae against Metalloproteinases 2 and 9 in Immune Defense Dual Protective Mechanisms of Matrix (2011) (0)
Abstract P2-06-03: Insulin receptor isoform signaling in breast cancer (2019) (0)
3 Expression and Regulation of IL-17 and IL-17 F 3 . 1 T H 17 Cells as a Novel Effector T (2011) (0)
New battlefi elds for costimulation (2006) (0)
B 7-H 3 Genes Characterization of Mouse and Human (2002) (0)
Reply to: GOT1 constrains TH17 cell differentiation, while promoting iTreg cell differentiation (2023) (0)
Differential involvement of p 38 mitogen-activated protein kinase kinases MKK 3 and MKK 6 in T-cell apoptosis (2013) (0)
Regulatory T cells and Th17 cells in immunity – function and plasticity (2010) (0)
Resistance of Th17 cells to Activation-Induced Cell Death (47.13) (2009) (0)
Research Highlight BATF: Bringing (in) Another Th17-regulating Factor (2009) (0)
Developmental requirements of T follicular helper cells (2009) (0)
Th17 Cells and Associated Cytokines in Inflammation and Cancer (2011) (0)
The roles of CARD9 in immune responses against intracellular bacterial infection (B170) (2007) (0)

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