Cheng‐xin Gong
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Philosophy Biology
Cheng‐xin Gong's Degrees
- Doctorate Medicine Columbia University
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(Suggest an Edit or Addition)Cheng‐xin Gong's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Tau pathology in Alzheimer disease and other tauopathies. (2005) (937)
- Tau in Alzheimer disease and related tauopathies. (2010) (783)
- Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation (2005) (692)
- O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease. (2004) (642)
- Mechanisms of tau-induced neurodegeneration (2009) (591)
- Tau and neurodegenerative disease: the story so far (2016) (547)
- Phosphoprotein Phosphatase Activities in Alzheimer Disease Brain (1993) (503)
- Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease. (2008) (468)
- Phosphatase Activity Toward Abnormally Phosphorylated τ: Decrease in Alzheimer Disease Brain (1995) (446)
- Deregulation of sphingolipid metabolism in Alzheimer's disease (2010) (436)
- Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes (2011) (428)
- Post-translational modifications of tau protein in Alzheimer’s disease (2005) (417)
- Phosphorylation of Microtubule-associated Protein Tau Is Regulated by Protein Phosphatase 2A in Mammalian Brain (2000) (407)
- Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease. (2009) (326)
- Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease (2008) (305)
- Dephosphorylation of Alzheimer Paired Helical Filaments by Protein Phosphatase-2A and −2B (*) (1995) (266)
- Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets (2012) (250)
- Tau exon 10 alternative splicing and tauopathies (2008) (241)
- Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease. (2009) (219)
- A Non-transgenic Mouse Model (icv-STZ Mouse) of Alzheimer’s Disease: Similarities to and Differences from the Transgenic Model (3xTg-AD Mouse) (2013) (213)
- Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome (2008) (203)
- The role of DYRK1A in neurodegenerative diseases (2011) (202)
- Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK‐3β (2002) (179)
- Role of protein phosphatase‐2A and ‐1 in the regulation of GSK‐3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain (2000) (179)
- Site‐specific effects of tau phosphorylation on its microtubule assembly activity and self‐aggregation (2007) (177)
- Truncation and Activation of Calcineurin A by Calpain I in Alzheimer Disease Brain* (2005) (169)
- Tau Becomes a More Favorable Substrate for GSK-3 When It Is Prephosphorylated by PKA in Rat Brain* (2004) (167)
- Brain glucose transporters, O‐GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer’s disease (2009) (166)
- Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase-2A (1994) (157)
- PP2A regulates tau phosphorylation directly and also indirectly via activating GSK-3beta. (2010) (155)
- Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases (2009) (148)
- Increased Dosage of Dyrk1A Alters Alternative Splicing Factor (ASF)-regulated Alternative Splicing of Tau in Down Syndrome*♦ (2008) (146)
- Alzheimer's Disease Abnormally Phosphorylated τ Is Dephosphorylated by Protein Phosphatase‐2B (Calcineurin) (1994) (146)
- Okadaic-acid-induced inhibition of protein phosphatase 2A produces activation of mitogen-activated protein kinases ERK1/2, MEK1/2, and p70 S6, similar to that in Alzheimer's disease. (2003) (141)
- Role of glycosylation in hyperphosphorylation of tau in Alzheimer's disease (2002) (137)
- Dephosphorylation of Tau by Protein Phosphatase 5 (2005) (133)
- Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles. (1998) (129)
- Dephosphorylation of microtubule‐associated protein tau by protein phosphatase‐1 and ‐2C and its implication in Alzheimer disease (1994) (128)
- Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlcNAcylation. (2006) (121)
- Down‐regulation of cAMP‐dependent protein kinase by over‐activated calpain in Alzheimer disease brain (2007) (117)
- PKA modulates GSK‐3β‐ and cdk5‐catalyzed phosphorylation of tau in site‐ and kinase‐specific manners (2006) (113)
- Anesthesia induces phosphorylation of tau. (2009) (112)
- Concurrent alterations of O‐GlcNAcylation and phosphorylation of tau in mouse brains during fasting (2006) (109)
- Inhibition of PP‐2A upregulates CaMKII in rat forebrain and induces hyperphosphorylation of tau at Ser 262/356 (2001) (109)
- From Chronic Cerebral Hypoperfusion to Alzheimer-Like Brain Pathology and Neurodegeneration (2014) (108)
- Tau passive immunization inhibits not only tau but also Aβ pathology (2017) (104)
- Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice (2014) (103)
- BDNF‐Akt‐Bcl2 antiapoptotic signaling pathway is compromised in the brain of autistic subjects (2010) (102)
- Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5 (2002) (97)
- Alzheimer disease therapeutics: focus on the disease and not just plaques and tangles. (2014) (97)
- Intranasal insulin ameliorates tau hyperphosphorylation in a rat model of type 2 diabetes. (2012) (95)
- Intranasal insulin restores insulin signaling, increases synaptic proteins, and reduces Aβ level and microglia activation in the brains of 3xTg-AD mice (2014) (95)
- The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome (2008) (94)
- Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation (2015) (91)
- Differential Effects of an O-GlcNAcase Inhibitor on Tau Phosphorylation (2012) (87)
- Multifactorial Hypothesis and Multi-Targets for Alzheimer's Disease. (2018) (87)
- Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A (2011) (86)
- Targeting Tau Protein in Alzheimer’s Disease (2010) (84)
- Quantitative proteomics identifies altered O‐GlcNAcylation of structural, synaptic and memory‐associated proteins in Alzheimer's disease (2017) (81)
- Dual-specificity Tyrosine Phosphorylation-regulated Kinase 1A (Dyrk1A) Modulates Serine/Arginine-rich Protein 55 (SRp55)-promoted Tau Exon 10 Inclusion* (2012) (81)
- Hyperphosphorylation-Induced Tau Oligomers (2013) (81)
- Regulation of phosphorylation of neuronal microtubule-associated proteins MAP1b and MAP2 by protein phosphatase-2A and -2B in rat brain (2000) (80)
- Subcutaneous administration of liraglutide ameliorates Alzheimer-associated tau hyperphosphorylation in rats with type 2 diabetes. (2013) (79)
- Developmental Regulation of Protein O-GlcNAcylation, O-GlcNAc Transferase, and O-GlcNAcase in Mammalian Brain (2011) (78)
- Intracerebroventricular Streptozotocin Exacerbates Alzheimer-Like Changes of 3xTg-AD Mice (2014) (77)
- Chronic cerebral hypoperfusion causes decrease of O-GlcNAcylation, hyperphosphorylation of tau and behavioral deficits in mice (2014) (76)
- Regulation between O‐GlcNAcylation and phosphorylation of neurofilament‐M and their dysregulation in Alzheimer disease (2008) (76)
- Dephosphorylation of microtubule‐associated protein tau by protein phosphatase 5 (2003) (75)
- Dysregulation of Protein Phosphorylation/Dephosphorylation in Alzheimer's Disease: A Therapeutic Target (2006) (74)
- Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies (2015) (74)
- Link Between DYRK1A Overexpression and Several-Fold Enhancement of Neurofibrillary Degeneration With 3-Repeat Tau Protein in Down Syndrome (2011) (73)
- Deregulation of brain insulin signaling in Alzheimer’s disease (2014) (73)
- Microtubule-associated protein tau as a therapeutic target in Alzheimer's disease (2014) (70)
- Truncation and activation of GSK-3β by calpain I: a molecular mechanism links to tau hyperphosphorylation in Alzheimer's disease (2015) (70)
- Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo (2019) (69)
- Inhibition of protein phosphatase 2A induces phosphorylation and accumulation of neurofilaments in metabolically active rat brain slices (2003) (68)
- Relevance of Phosphorylation and Truncation of Tau to the Etiopathogenesis of Alzheimer’s Disease (2018) (68)
- O-GlcNAcylation regulates ischemia-induced neuronal apoptosis through AKT signaling (2015) (66)
- Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice (2018) (66)
- Mechanism of neurofibrillary degeneration and pharmacologic therapeutic approach. (2000) (65)
- O-GlcNAcylation: A regulator of tau pathology and neurodegeneration (2016) (65)
- Brain Gene Expression of a Sporadic (icv-STZ Mouse) and a Familial Mouse Model (3xTg-AD Mouse) of Alzheimer’s Disease (2012) (64)
- Dysregulation of tau phosphorylation in mouse brain during excitotoxic damage. (2009) (63)
- Alzheimer's disease neurofibrillary degeneration: pivotal and multifactorial. (2010) (61)
- Elevation of the level and activity of acid ceramidase in Alzheimer's disease brain (2004) (60)
- Subcellular distribution of protein phosphatases and abnormally phosphorylated τ in the temporal cortex from Alzheimer's disease and control brains (1998) (60)
- Injection of okadaic acid into the meynert nucleus basalis of rat brain induces decreased acetylcholine level and spatial memory deficit (2004) (59)
- Up-regulation of cell division cycle (cdc) 2 kinase in neurons with early stage Alzheimer's disease neurofibrillary degeneration (2002) (57)
- Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation (2015) (57)
- TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease (2010) (56)
- Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice (2017) (55)
- CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer’s disease (2013) (53)
- Cyclic AMP-dependent Protein Kinase Regulates the Alternative Splicing of Tau Exon 10 (2011) (53)
- Regulation of alternative splicing of tau exon 10 by 9G8 and Dyrk1A (2012) (52)
- Significance and mechanism of alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion (2002) (52)
- O‐GlcNAcylation of protein kinase A catalytic subunits enhances its activity: a mechanism linked to learning and memory deficits in Alzheimer's disease (2016) (50)
- Intranasal Insulin Prevents Anesthesia-Induced Spatial Learning and Memory Deficit in Mice (2016) (49)
- Inhibition of Protein Synthesis Alters Protein Degradation through Activation of Protein Kinase B (AKT)* (2013) (49)
- Targeting Insulin Signaling for the Treatment of Alzheimer's Disease. (2015) (49)
- Transactive response DNA-binding protein 43 (TDP-43) regulates alternative splicing of tau exon 10: Implications for the pathogenesis of tauopathies (2017) (49)
- Inhibition of protein phosphatase-2B (calcineurin) activity towards Alzheimer abnormally phosphorylated τ by neuroleptics (1996) (49)
- Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice (2015) (48)
- Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I (2015) (46)
- Bilateral injection of isoproterenol into hippocampus induces Alzheimer‐like hyperphosphorylation of tau and spatial memory deficit in rat (2005) (44)
- Intranasal insulin prevents anesthesia-induced hyperphosphorylation of tau in 3xTg-AD mice (2014) (44)
- Hyperphosphorylation of tau and protein phosphatases in Alzheimer disease. (2006) (43)
- Corrigendum: Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation (2016) (43)
- TDP-43 suppresses tau expression via promoting its mRNA instability (2016) (41)
- Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. (2008) (40)
- Opposite effects of two estrogen receptors on tau phosphorylation through disparate effects on the miR-218/PTPA pathway (2015) (39)
- Metabolically active rat brain slices as a model to study the regulation of protein phosphorylation in mammalian brain. (2001) (39)
- Mechanism of neurofibrillary degeneration in Alzheimer's disease (1994) (39)
- Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain (2015) (37)
- Activation of protein phosphatase 2B and hyperphosphorylation of Tau in Alzheimer's disease. (2011) (37)
- Diverse regulation of AKT and GSK‐3β by O‐GlcNAcylation in various types of cells (2012) (36)
- Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis (2017) (36)
- Truncation of Tau selectively facilitates its pathological activities (2020) (32)
- Recent developments with tau-based drug discovery (2018) (31)
- Phenylbutyric acid prevents rats from electroconvulsion-induced memory deficit with alterations of memory-related proteins and tau hyperphosphorylation (2010) (28)
- O-GlcNAc cycling modulates neurodegeneration (2012) (27)
- Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) enhances tau expression. (2013) (26)
- Alzheimer neurofibrillary degeneration (2007) (26)
- Pathological Alterations of Tau in Alzheimer’s Disease and 3xTg-AD Mouse Brains (2019) (25)
- NF-κB precursor, p105, and NF-κB inhibitor, IκBγ, are both elevated in Alzheimer disease brain (2005) (24)
- O-GlcNAcylation Reduces Ischemia-Reperfusion–Induced Brain Injury (2017) (24)
- Intranasal Insulin Prevents Anesthesia-Induced Cognitive Impairment and Chronic Neurobehavioral Changes (2017) (24)
- GSK-3β is Dephosphorylated by PP2A in a Leu309 Methylation-Independent Manner. (2015) (22)
- Alzheimer’s disease brain contains tau fractions with differential prion-like activities (2021) (21)
- Molecular pathology of Alzheimer neurofibrillary degeneration. (1993) (21)
- Splicing factor SC35 promotes tau expression through stabilization of its mRNA (2011) (19)
- Up-regulation of casein kinase 1ε is involved in tau pathogenesis in Alzheimer’s disease (2017) (19)
- Anesthetics and tau protein: animal model studies. (2010) (19)
- Intranasal Administration of Insulin Reduces Chronic Behavioral Abnormality and Neuronal Apoptosis Induced by General Anesthesia in Neonatal Mice (2019) (18)
- Calpain I Activation Causes GLUT3 Proteolysis and Downregulation of O-GlcNAcylation in Alzheimer's Disease Brain. (2018) (18)
- Pharmacological targets to inhibit Alzheimer neurofibrillary degeneration. (2002) (17)
- Young blood plasma reduces Alzheimer’s disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice (2020) (16)
- Cyclic AMP‐dependent protein kinase regulates 9G8‐mediated alternative splicing of tau exon 10 (2012) (16)
- NF-kappaB precursor, p105, and NF-kappaB inhibitor, IkappaBgamma, are both elevated in Alzheimer disease brain. (2005) (15)
- Multiple Forms of Phosphatase from Human Brain: Isolation and Partial Characterization of Affi-Gel Blue Nonbinding Phosphatase Activities (2001) (14)
- Neuronal O-GlcNAc transferase regulates appetite, body weight, and peripheral insulin resistance (2018) (14)
- Intermittent fasting promotes adult hippocampal neuronal differentiation by activating GSK‐3β in 3xTg‐AD mice (2020) (13)
- Protein Phosphatase 1 dephosphorylates TDP‐43 and suppresses its function in tau exon 10 inclusion (2018) (13)
- Neonatal Exposure to Anesthesia Leads to Cognitive Deficits in Old Age: Prevention with Intranasal Administration of Insulin in Mice (2020) (12)
- Cyclic AMP-Dependent Protein Kinase Enhances SC35-Promoted Tau Exon 10 Inclusion (2014) (11)
- A Non-transgenic Mouse Model (icv-STZ Mouse) of Alzheimer’s Disease: Similarities to and Differences from the Transgenic Model (3xTg-AD Mouse) (2012) (11)
- Elevation of casein kinase 1ε associated with TDP‐43 and tau pathologies in Alzheimer's disease (2020) (11)
- Multiple Forms of Phosphatase from Human Brain: Isolation and Partial Characterization of Affi-Gel Blue Binding Phosphatases (2004) (10)
- Multi-Targets: An Unconventional Drug Development Strategy for Alzheimer’s Disease (2022) (10)
- Inhibition of glycogen synthase kinase-3 reverses tau hyperphosphorylation induced by Pin1 down-regulation. (2013) (10)
- Regulation of microtubule-associated proteins, protein kinases and protein phosphatases during differentiation of SY5Y cells. (2004) (10)
- Molecular Connection Between Diabetes and Dementia. (2019) (9)
- C‐terminal truncation of GSK‐3β enhances its dephosphorylation by PP2A (2017) (9)
- Anesthesia with sevoflurane or isoflurane induces severe hypoglycemia in neonatal mice (2020) (9)
- Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic mice (2019) (8)
- Losartan-induced hypotension leads to tau hyperphosphorylation and memory deficit. (2014) (8)
- Intranasal Insulin Increases Synaptic Protein Expression and Prevents Anesthesia-Induced Cognitive Deficits Through mTOR-eEF2 Pathway. (2019) (8)
- Glycogen synthase kinase-3β suppresses the expression of protein phosphatase methylesterase-1 through β-catenin (2019) (6)
- Cyclic AMP-dependent protein kinase regulates the alternative splicing of tau exon 10: a mechanism involved in tau pathology of Alzheimer's disease (2011) (5)
- Phenylbutyric acid protects against spatial memory deficits in a model of repeated electroconvulsive therapy. (2014) (5)
- Alzheimer Neurofibrillary Degeneration: A Feasible and Key Target for Therapeutics (1997) (5)
- Glycosylation of tau protein occurs earlier than its hyperphosphorylation in Alzheimer's disease (2000) (3)
- Seeding-Competent Tau in Gray Matter Versus White Matter of Alzheimer's Disease Brain. (2021) (2)
- Rbfox3/NeuN Regulates Alternative Splicing of Tau Exon 10. (2018) (2)
- Pivotal Role of Neurofibrillary Degeneration in Alzheimer Disease and Therapeutic Targets (2004) (2)
- Thiamme2-G, A Novel O-GlcNAcase Inhibitor, Reduces Tau Hyperphosphorylation and Rescues Cognitive Impairment in Mice. (2021) (2)
- Mechanism of neurofibrillary degeneration (2000) (2)
- DSSylation, a novel guide for protein degradation? (2014) (2)
- High Mobility Group Box 1 Ameliorates Cognitive Impairment in the 3×Tg-AD Mouse Model. (2020) (2)
- Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation (2022) (2)
- 534 Tau-pathology in brain of rats after chronic treatment with okadaic acid (1996) (2)
- Expression of Microtubule Associated Protein Tau in Mouse Pancreatic Islets Is Restricted to Autonomic Nerve Fibers. (2020) (2)
- Sevoflurane-induced neuronal apoptosis in neonatal mice is prevented with intranasal administration of insulin. (2020) (2)
- Intranasal insulin prevents anesthesia-induced spatial memory deficit in mice (2015) (2)
- P3-251 Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain (2004) (1)
- C-TERMINAL TRUNCATION OF GSK-3β ENHANCES ITS DEPHOSPHORYLATION BY PP2A (2017) (1)
- P2-128 Regulation of microtubule-associated proteins, protein kinases, and protein phosphatases during differentiation of SY5Y cells (2004) (1)
- Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice (2014) (1)
- Pathological Alterations of Tau in Alzheimer’s Disease and 3xTg-AD Mouse Brains (2019) (1)
- CREB regulates the expression of neuronal glucose transporter 3: A mechanism leading to impaired brain glucose uptake in Alzheimer's disease (2012) (1)
- Deregulation of brain insulin signaling in Alzheimer’s disease (2014) (1)
- INTRANASAL ADMINISTRATION OF INSULIN PREVENTS ANESTHESIA-INDUCED COGNITIVE IMPAIRMENT AND CHRONIC NEUROBEHAVIORAL CHANGES (2017) (1)
- Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice (2018) (1)
- ABNORMALLY PHOSPHORYLATED TAU IN ALZHEIMER DISEASE BRAIN: ROLE OF PHOSPHOPROTEIN PHOSPHATASES (1993) (1)
- TAU- PATHOLOGY IN HIPPOCAMP AL FORMATION OF AGED DOGS AND RATS CHRONICALLY TREATED WITH OKADAIC ACID (1997) (1)
- Tau and beyond for Alzheimer's disease. (2013) (1)
- Tau seeding activity in various regions of down syndrome brain assessed by two novel assays (2022) (1)
- Inge Grundke-Iqbal: A Legacy of Tau in the Etiology of Alzheimer Disease (1937–2012) (2012) (1)
- Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase 2A and 2B J.Z. Wang, C.-X. Gong, I. Grundke-Iqbal and K. Iqbal. NYS Institute for Basic Research in Developmental Disabilities, Staten Island, NY 10314 USA (1994) (1)
- PATHOLOGICAL TAU FROM ALZHEIMER'S BRAIN INDUCES SITE-SPECIFIC HYPERPHOSPHORYLATION AND SDS- AND REDUCING AGENT-RESISTANT HIGH MOLECULAR WEIGHT AGGREGATION OF TAU IN VIVO (2019) (1)
- Splicing factor SC35 regulates the alternative splicing of tau exon 10 (2010) (0)
- P2-142: Decreased protein phosphatase 2A in Down syndrome brain: A cause of neurofibrillary degeneration (2008) (0)
- Up-regulation of casein kinase 1ε is involved in tau pathogenesis in Alzheimer’s disease (2017) (0)
- O2-05-06 Impaired glucose uptake/metabolism contributes to hyperphosphorylation of tau via reduction of O-GLCnacylation: a novel mechanism involved in Alzheimer disease (2004) (0)
- Molecular pathology of Alzheimer neurofibrillary (2009) (0)
- Regulation of Akt by O-GlcNAcylation in various cell types: implication in Alzheimer's Disease (2010) (0)
- CYCLIC AMP-DEPENDENT PROTEIN KINASE PHOSPHORYLATES TDP-43 AND MODULATES ITS FUNCTION IN TAU MRNA PROCESSING (2019) (0)
- A life dedicated to Alzheimer’s disease research: in memory of Inge Grundke-Iqbal (1937–2012) (2012) (0)
- TAU IMMUNOTHERAPY PREVENTS THE SPREAD AND PROMOTES THE CLEARANCE OF PATHOLOGY IN MICE (2017) (0)
- Neurofibrillary degeneration: a promising target for the treatment of Alzheimer’s disease and other tauopathies (2005) (0)
- INTRANASAL ADMINISTRATION OF INSULIN PREVENTS CHRONIC COGNITIVE IMPAIRMENT AND NEURONAL APOPTOSIS INDUCED BY GENERAL ANESTHESIA IN NEONATAL MICE (2019) (0)
- Young blood plasma reduces Alzheimer’s disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice (2020) (0)
- P1-267 Alterations of glycoproteins in Alzheimer disease brain (2004) (0)
- 516 Expression of protein kinase GSK-3 and protein phosphatases PP-1, PP 2A, and PP-2B in the brain of patients with Alzheimer's disease (1996) (0)
- Truncation of GSK-3β by activated calpain I in Alzheimer brain enhances its biological activity (2010) (0)
- Modulation of O‐GlcNAc levels as a disease modifying approach for Alzheimer disease (223.3) (2014) (0)
- Intracerebroventricular Streptozotocin Exacerbates Alzheimer-Like Changes of 3xTg-AD Mice (2013) (0)
- Metabolically active rat brain slices as a model for studying neurofibrillary degeneration of Alzheimer's disease (2000) (0)
- Why delay in effective treatment for Alzheimer's disease and related conditions. (2019) (0)
- 533 Isolation of protein phosphatase 2B calcineurin from Alzheimer disease and control autopsied brains (1996) (0)
- Tau antibody 77G7 targeting microtubule binding domain suppresses oligomeric tau to seed tau aggregation (2022) (0)
- O2-05-08: Protein O-Glcnacylation: A novel mechanism involved in Alzheimer's disease (2008) (0)
- P3-304 Mnb/Dyrk1A primes phosphorylation of tau at several phosphorylation sites by GSK-3β (2006) (0)
- P2-148: Involvement of 9G8 in alternative splicing of tau exon 10 (2008) (0)
- Gut Microbiota and Immunotherapy for Alzheimer’s Disease (2022) (0)
- P2-145: Regulation of ASF-mediated alternative splicing of tau exon 10 by PKA (2008) (0)
- P3-263 Phosphorylation of tau is regulated by O-Glcnacylation (2004) (0)
- Neonatal Exposure to Anesthesia Leads to Cognitive Deficits in Old Age: Prevention with Intranasal Administration of Insulin in Mice (2020) (0)
- TEMPLATION AND PROPAGATION OF TAU PATHOLOGY BY ALZHEIMER TAU IN C57BL/6 MICE (2018) (0)
- Effect of Peripheral Insulin Administration on Phosphorylation of Tau in the Brain. (2020) (0)
- Alzheimer--like tau phosphorylation induced by dysregulated insulin signal transduction and impaired glucose metabolism in type 1 diabetes millitus (2006) (0)
- AKT/GSK-3β signaling is altered through downregulation of mTOR during cerebral Ischemia/Reperfusion injury (2022) (0)
- Related articles (2014) (0)
- Dysregulation of brain insulin signaling: A mechanistic link between diabetes and Alzheimer's disease (2010) (0)
- Alzheimer’s disease brain contains tau fractions with differential prion-like activities (2021) (0)
- DSSylation, a novel guide for protein degradation? (2014) (0)
- P2-147: Modulation of SRp55-regulated alternative splicing of tau exon 10 by Dyrk1A (2008) (0)
- Molecular basis of cognitive improvement of pioglitazone and rosiglitazone (2010) (0)
- S3-03-01 O-glycosylation regulates phosphorylation of tau:A novel mechanism leading to neurofibrillarydegeneration in Alzheimer disease (2006) (0)
- Cerebral ischemia-induced elevation of O-GlcNAcylation causes AKT inhibition and apoptosis (2012) (0)
- From Chronic Cerebral Hypoperfusion to Alzheimer-Like Brain Pathology and Neurodegeneration (2014) (0)
- Role of protein kinases, protein phosphatases and extracellular signals in the abnormal hyperphosphorylation of tau (2000) (0)
- Two simple assays for assessing the seeding activity of proteopathic tau (2023) (0)
- Molecular basis of diabetes as a risk for Alzheimer's disease (2010) (0)
- Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic mice (2019) (0)
- O4-02-05: Molecular mechanism by which type 2 diabetes mellitus increases the risk for Alzheimer's disease (2008) (0)
- Does proteopathic tau propagate trans-synaptically in the brain? (2022) (0)
- Does proteopathic tau propagate trans-synaptically in the brain? (2022) (0)
- O-GlcNAcylated tau: A link between impaired glucose metabolism and neurodegeneration in Alzheimer's disease (2012) (0)
- NF-κB in Brain Diseases (2011) (0)
- Truncation of GSK-3beta by calpain I contributes to the hyperphosphorylation of tau in the Alzheimer's brain (2012) (0)
- O-GlcNAcylation Reduces Ischemia-Reperfusion–Induced Brain Injury (2017) (0)
- TDP-43 REGULATES ALTERNATIVE SPLICING OF TAU EXON 10: IMPLICATION IN THE PATHOGENESIS OF TAUOPATHIES (2017) (0)
- Cyclic AMP-Dependent Protein Kinase Enhances SC35-Promoted Tau Exon 10 Inclusion (2013) (0)
- P3-248 Activation of calpain I in Alzheimer disease brain negatively regulates CREB (2006) (0)
- Excitotoxic damage deregulates tau phosphorylation: Implication to Alzheimer's disease (2009) (0)
- 572 Role of abnormal phosphorylation and glycosylation of tau in the formation of tangles and neurofibrillary degeneration (1996) (0)
- Truncation and activation of Dyrk1A in Alzheimer's disease brain by activated calpain I (2009) (0)
- IMMUNOTHERAPY-TARGETING TAU BLOCKS TAU PATHOLOGY INDUCED BY ALZHEIMER’S HYPERPHOSPHORYLATED TAU IN TRIPLE-TRANSGENIC AD MICE (2018) (0)
- O-GLCNACYLATION AMELIORATES ISCHEMIA-INDUCED CEREBRAL INJURY (2016) (0)
- Tau seeding activity in various regions of down syndrome brain assessed by two novel assays (2022) (0)
- Tau passive immunization inhibits not only tau but also Aβ pathology (2017) (0)
- Upregulation of casein kinase 1 epsilon may be involved in tau pathology in Alzheimer's disease brain (2013) (0)
- Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice (2017) (0)
- The expression and purification of recombinant O-GLcNAc transferase in insect cells (2003) (0)
- P3-230 Tau phosphorylation induced by dysregulated insulin signal transduction and impaired glucose metabolism in type 1 diabetes mellitus (2006) (0)
- Protein Kinase B (AKT) Protein Degradation through Activation of Inhibition of Protein Synthesis Alters (2014) (0)
- Dyrk 1 A regulate the alternative splicing of tau exon 10 1 Dual-specificity tyrosine-phosphorylated and regulated kinase 1 A ( Dyrk 1 A ) modulates serine-arginine rich protein 55 ( SRp 55 )-promoted tau exon (2012) (0)
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