Chris Orvig
#139,806
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Bioinorganic chemist
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Chris Orvigchemistry Degrees
Chemistry
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Inorganic Chemistry
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Chemistry
Chris Orvig's Degrees
- PhD Inorganic Chemistry University of British Columbia
- Bachelors Chemistry University of British Columbia
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(Suggest an Edit or Addition)Chris Orvig's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Metallodrugs in medicinal inorganic chemistry. (2014) (827)
- Vanadium compounds as insulin mimics. (1999) (635)
- Matching chelators to radiometals for radiopharmaceuticals. (2014) (559)
- Biosorbents for hexavalent chromium elimination from industrial and municipal effluents (2010) (478)
- Vanadium in diabetes: 100 years from Phase 0 to Phase I. (2006) (436)
- Vanadium treatment of type 2 diabetes: a view to the future. (2009) (427)
- Medicinal inorganic chemistry: introduction. (1999) (407)
- Bis(maltolato)oxovanadium(IV) is a potent insulin mimic. (1992) (354)
- Boon and Bane of Metal Ions in Medicine (2003) (323)
- Design of targeting ligands in medicinal inorganic chemistry. (2006) (262)
- Medicinal inorganic chemistry approaches to passivation and removal of aberrant metal ions in disease. (2009) (252)
- Metal complexes in medicinal chemistry: new vistas and challenges in drug design. (2006) (246)
- Reaction chemistry of BMOV, bis(maltolato)oxovanadium(IV), a potent insulin mimetic agent (1995) (210)
- Radioactive Main Group and Rare Earth Metals for Imaging and Therapy. (2018) (196)
- Potentiometric, Calorimetric, and Solution NMR Studies of a Tridentate Ligand Which has a Marked Preference for Formation of Bis(ligand) versus Mono(ligand) Lanthanide Complexes and Which Exhibits High Selectivity for Heavier Lanthanides (1995) (192)
- Tumour targeting with radiometals for diagnosis and therapy. (2013) (185)
- Synthesis and characterization of lanthanide [Ln(L)]2 complexes of N4O3 amine phenol ligands with phenolate oxygen bridges: evidence for very weak magnetic exchange between lanthanide ions (1992) (168)
- Speciation of aluminum in biological systems. (1996) (157)
- Preparation and characterization of vanadyl complexes with bidentate maltol-type ligands; in vivo comparisons of anti-diabetic therapeutic potential (2002) (148)
- Design of vanadium compounds as insulin enhancing agents (2000) (139)
- Cellular Transport Mechanisms of Cytotoxic Metallodrugs: An Overview beyond Cisplatin (2014) (139)
- Synthesis and characterization of dual function vanadyl, gallium and indium curcumin complexes for medicinal applications. (2005) (138)
- The art of building multifunctional metal-binding agents from basic molecular scaffolds for the potential application in neurodegenerative diseases (2012) (130)
- Synthesis, characterization, and metal coordinating ability of multifunctional carbohydrate-containing compounds for Alzheimer's therapy. (2007) (129)
- Neutral water-soluble aluminum complex of neurological interest (1986) (128)
- New insights into the interactions of serum proteins with bis(maltolato)oxovanadium(IV): transport and biotransformation of insulin-enhancing vanadium pharmaceuticals. (2005) (127)
- Acyclic chelate with ideal properties for (68)Ga PET imaging agent elaboration. (2010) (121)
- Metal complexes of maltol and close analogues in medicinal inorganic chemistry. (2006) (120)
- Vanadium Complexes as Insulin Mimetic Agents: Coordination Chemistry and in Vivo Studies of Oxovanadium(IV) and Dioxovanadate(V) Complexes Formed from Naturally Occurring Chelating Oxazolinate, Thiazolinate, or Picolinate Units† (1999) (108)
- Combating Alzheimer's disease with multifunctional molecules designed for metal passivation. (2007) (104)
- Neutral water-soluble post-transition-metal chelate complexes of medical interest: aluminum and gallium tris(3-hydroxy-4-pyronates) (1987) (100)
- Comparison of anti-hyperglycemic effect amongst vanadium, molybdenum and other metal maltol complexes. (2004) (99)
- Structural, Spectroscopic, Thermodynamic and Kinetic Properties of Copper(II) Complexes with Tripodal Tetraamines. (1998) (99)
- Complementary inhibition of synoviocyte, smooth muscle cell or mouse lymphoma cell proliferation by a vanadyl curcumin complex compared to curcumin alone. (2004) (98)
- Kinetic analysis and comparison of uptake, distribution, and excretion of 48V-labeled compounds in rats. (1998) (96)
- Vanadyl-biguanide complexes as potential synergistic insulin mimics. (1999) (94)
- Insulin-enhancing vanadium(III) complexes. (2001) (94)
- Comparison of the glucose-lowering properties of vanadyl sulfate and bis(maltolato)oxovanadium(IV) following acute and chronic administration. (1995) (92)
- A Perspective - can copper complexes be developed as a novel class of therapeutics? (2017) (91)
- Glucose-lowering effects of a new organic vanadium complex, bis(maltolato)oxovanadium(IV). (1993) (91)
- Lanthanide containing compounds for therapeutic care in bone resorption disorders. (2007) (87)
- Glucose-lowering properties of vanadium compounds: comparison of coordination complexes with maltol or kojic acid as ligands. (1997) (86)
- Werner coordination chemistry and neurodegeneration. (2013) (86)
- Ion exchange in hydroxyapatite with lanthanides. (2015) (85)
- Aluminum and gallium compounds of 3-hydroxy-4-pyridinones: synthesis, characterization, and crystallography of biologically active complexes with unusual hydrogen bonding (1988) (80)
- Preparation of oxobis(dithiolato) complexes of technetium(V) and rhenium(V) (1980) (80)
- Improvement in cardiac dysfunction in streptozotocin-induced diabetic rats following chronic oral administration of bis(maltolato)oxovanadium(IV). (1993) (78)
- H4octapa: an acyclic chelator for 111In radiopharmaceuticals. (2012) (76)
- A new class of oxotechnetium(5+) chelate complexes containing a TcON2S2 core (1981) (76)
- Characterization of the Potent Insulin Mimetic Agent Bis(maltolato)oxovanadium(IV) (BMOV) in Solution by EPR Spectroscopy. (1996) (75)
- Coordination chemistry of 2-(2'-hydroxyphenyl)-2-oxazolines with aluminum, gallium, and indium: first tris(ligand)metal(III) complexes of this naturally occurring binding group (1992) (73)
- Carbohydrate conjugates for molecular imaging and radiotherapy: 99mTc(I) and 186Re(I) tricarbonyl complexes of N-(2'-Hydroxybenzyl)-2-amino-2-deoxy-D-glucose. (2004) (72)
- Complexes of Trivalent Metal Ions with Potentially Heptadentate N4O3 Schiff Base and Amine Phenol Ligands of Varying Rigidity (1995) (69)
- RGD conjugates of the H2dedpa scaffold: synthesis, labeling and imaging with 68Ga. (2012) (65)
- 99m-Technetium carbohydrate conjugates as potential agents in molecular imaging. (2008) (64)
- Carbohydrate-appended 2,2'-dipicolylamine metal complexes as potential imaging agents. (2005) (63)
- Heptadentate ligands for the lanthanides. The first structurally characterized example of a lanthanide heptadentate ligand complex: [tris(3-aza-4-methyl-6-oxohept-4-en-1-yl)amine]ytterbium(III) (1991) (63)
- Lipophilic coordination compounds: aluminum, gallium, and indium complexes of 1-aryl-3-hydroxy-2-methyl-4-pyridinones (1991) (63)
- Cytotoxicity of the traditional chinese medicine (TCM) plumbagin in its copper chemistry. (2009) (63)
- New class of oxotechnetium (5+) chelate complexes containing a TcON/sub 2/S/sub 2/ core (1981) (62)
- Structural characteristics of chloroquine-bridged ferrocenophane analogues of ferroquine may obviate malaria drug-resistance mechanisms. (2013) (62)
- Vanadium compounds in the treatment of diabetes. (2004) (61)
- H(4)octapa-trastuzumab: versatile acyclic chelate system for 111In and 177Lu imaging and therapy. (2013) (61)
- Increased potency of vanadium using organic ligands (1995) (60)
- Geometric Factors in the Structural and Thermodynamic Properties of Copper(II) Complexes with Tripodal Tetraamines (1996) (60)
- Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) liriodenine with metal ions, and DNA binding studies. (2009) (59)
- N-Aryl-substituted 3-(β-D-glucopyranosyloxy)-2-methyl-4(1H)-pyridinones as agents for Alzheimer's therapy (2011) (58)
- Physical and structural studies of N-substituted-3-hydroxy-2-methyl-4(1H)-pyridinones (1988) (58)
- A glucosamine-dipicolylamine conjugate of 99mTc(I) and 186Re(I) for use in imaging and therapy. (2005) (58)
- Novel carbohydrate-appended metal complexes for potential use in molecular imaging. (2004) (57)
- Vanadium complexes with mixed O,S anionic ligands derived from maltol: synthesis, characterization, and biological studies. (2005) (55)
- Synthesis and insulin-mimetic activities of metal complexes with 3-hydroxypyridine-2-carboxylic acid. (2005) (55)
- Bis(ligand) Rhenium(V) and Technetium(V) Complexes of Two Naturally Occurring Binding Moieties (Oxazoline and Thiazoline). (1996) (55)
- Homotrinuclear lanthanide(III) arrays: assembly of and conversion from mononuclear and dinuclear units. (2000) (54)
- Comparison of ligands of differing denticity and basicity for the in vivo chelation of aluminium and gallium (1990) (52)
- Two-dimensional (2D) pulsed electron paramagnetic resonance study of VO(2+)-triphosphate interactions: evidence for tridentate triphosphate coordination, and relevance to bone uptake and insulin enhancement by vanadium pharmaceuticals. (2002) (52)
- Divalent later transition metal complexes of the traditional chinese medicine (TCM) liriodenine: coordination chemistry, cytotoxicity and DNA binding studies. (2009) (52)
- Molecular architectures for trimetallic d/f/d complexes: structural and magnetic properties of a LnNi2 core. (2008) (51)
- Chemical and in vivo studies of the anion oxo[N,N'-ethylenebis(2-mercaptoacetimido)]Technetate(V). (1982) (51)
- Synthesis, structure, and biological activity of ferrocenyl carbohydrate conjugates. (2006) (51)
- Oxidation Kinetics of the Potent Insulin Mimetic Agent Bis(maltolato)oxovanadium(IV) (BMOV) in Water and in Methanol. (1996) (50)
- Exploring the potential of gold(III) cyclometallated compounds as cytotoxic agents: variations on the C^N theme. (2015) (50)
- Effects of low and high dose administration of bis(maltolato)oxovanadium(IV) on fa/fa Zucker rats. (1996) (50)
- Synthesis and insulinomimetic activities of novel mono- and tetranuclear oxovanadium(IV) complexes with 3-hydroxypyridine-2-carboxylic acid. (2004) (50)
- Glucosamine conjugates of tricarbonylcyclopentadienyl rhenium(I) and technetium(I) cores. (2006) (49)
- Reduction of [VO2(ma)2]- and [VO2(ema)2]- by ascorbic acid and glutathione: kinetic studies of pro-drugs for the enhancement of insulin action. (2002) (49)
- Carbohydrate-appended 3-hydroxy-4-pyridinone complexes of the [M(CO)3]+ core (M = Re, 99mTc, 186Re). (2006) (49)
- Rhenium(V) and technetium(V) complexes of bis(o-hydroxyphenyl)phenylphosphine (PO{sub 2}{sup 2-}) and (o-hydroxyphenyl)diphenylphosphine (PO{sup -}) ligands (1995) (48)
- The complexation of aluminum with N-substituted 3-hydroxy-4-pyridinones (1989) (48)
- Evaluation of the H2)dedpa scaffold and its cRGDyK conjugates for labeling with 64Cu. (2012) (48)
- Coordination chemistry and insulin-enhancing behavior of vanadium complexes with maltol C6H6O3 structural isomers. (2005) (47)
- Bulky ortho 3-methoxy groups on N4O3 amine phenol ligands producing six-coordinate bis(ligand)lanthanide complex cations [Ln(H3L)2]3+ (Ln = Pr, Gd; H3L = tris(((2-hydroxy-3-methoxybenzyl)amino)ethyl)amine) (1993) (47)
- Solution chemistry of gallium and indium 3-hydroxy-4-pyridinone complexes in vitro and in vivo (1990) (46)
- Octadentate Picolinic Acid-Based Bispidine Ligand for Radiometal Ions. (2017) (45)
- Unprecedented sugar-dependent in vivo antitumor activity of carbohydrate-pendant cis-diamminedichloroplatinum(II) complexes. (2001) (45)
- An Iron-Based Molecular Redox Switch as a Model for Iron Release from Enterobactin via the Salicylate Binding Mode. (1999) (43)
- Influence of chelation and oxidation state on vanadium bioavailability, and their effects on tissue concentrations of zinc, copper, and iron (2002) (43)
- In vitro studies of 3-hydroxy-4-pyridinones and their glycosylated derivatives as potential agents for Alzheimer's disease. (2010) (43)
- Coordination chemistry of 2-(2'-hydroxyphenyl)-2-benzoxazole with gallium(III) and aluminum(III): two uncommon Group 13 metal environments stabilized by a biologically relevant binding group (1993) (42)
- Vanadyl-thiazolidinedione combination agents for diabetes therapy. (2003) (41)
- Editorial: lanthanide compounds for therapeutic and diagnostic applications. (2006) (41)
- H2CHXdedpa and H4CHXoctapa-chiral acyclic chelating ligands for (67/68)Ga and (111)In radiopharmaceuticals. (2015) (41)
- H6phospa-trastuzumab: bifunctional methylenephosphonate-based chelator with 89Zr, 111In and 177Lu. (2014) (41)
- Group 13 and lanthanide complexes with mixed O,S anionic ligands derived from maltol. (2005) (40)
- H(2)azapa: a versatile acyclic multifunctional chelator for (67)Ga, (64)Cu, (111)In, and (177)Lu. (2012) (40)
- Dlf complexes with uniform coordination geometry: structural and magnetic properties of an LnNi2 core supported by a heptadentate amine phenol ligand. (2003) (39)
- Evidence for energy-dependent transport of aluminum out of brain extracellular fluid. (1995) (39)
- Polydentate ligand chemistry of Group 13 metals: effects of the size and donor selectivity of metal ions on the structures and properties of aluminum, gallium, and indium complexes with potentially heptadentate (N4O3) amine phenol ligands (1992) (39)
- Glycosylated tetrahydrosalens as multifunctional molecules for Alzheimer's therapy. (2009) (38)
- Effects of diabetes, vanadium, and insulin on glycogen synthase activation in Wistar rats (2002) (38)
- Neutral water-soluble indium complexes of 3-hydroxy-4-pyrones and 3-hydroxy-4-pyridinones (1988) (38)
- Vanadium compounds as insulin mimics. (1999) (37)
- [(μ-OCH3)VO(ma)]2, a Strongly Antiferromagnetic Oxovanadium(IV) Dimer (1998) (37)
- Highly flexible chelating ligands for group 13 metals : design and synthesis of hexadentate (N3O3) tripodal amine phenol ligand complexes of aluminum, gallium, and indium (1993) (37)
- Coaggregation of paramagnetic d- and f-block metal ions with a podand-framework amine phenol ligand. (2000) (37)
- Sugar-pendant diamines. (2001) (36)
- Lanthanide complexes of potentially heptadentate ligands including the structure of [tris(3-aza-4-methylhept-4-ene-6-on-1-yl)amine]tris(nitrato)gadolinium(III) (1988) (36)
- Aluminum and gallium complexes of 1-ethyl-3-hydroxy-2-methyl-4-pyridinone: a new exoclathrate matrix (1989) (36)
- Hexadentate N4O2 Amine Phenol Complexes of Gallium and Indium (1995) (36)
- Tripodal Aminophenolate Ligand Complexes of Aluminum(III), Gallium(III), and Indium(III) in Water (1997) (35)
- Carbohydrate-bearing 3-hydroxy-4-pyridinonato complexes of gallium(III) and indium(III). (2005) (34)
- Multi-Target Metal-Based Anticancer Agents. (2017) (34)
- Structural characterization of the octachloroditechnetate(III) ion in its tetrabutylammonium salt (1981) (33)
- In vitro studies of lanthanide complexes for the treatment of osteoporosis. (2013) (33)
- New Ga derivatives of the H2dedpa scaffold with improved clearance and persistent heart uptake. (2011) (33)
- Altering pyridinone N-substituents to optimise activity as potential prodrugs for Alzheimer's disease. (2008) (32)
- Gallium and Indium Complexes of Hexadentate Ligands Containing Pendant Pyridyl and Phenolate Groups (1995) (32)
- Calorimetric studies of the interaction between the insulin-enhancing drug candidate bis(maltolato)oxovanadium(IV) (BMOV) and human serum apo-transferrin. (2009) (32)
- Effects of sequential replacement of -NH2 by -OH in the tripodal tetraamine tren on its acidity and metal ion coordinating properties. (2001) (31)
- What a Difference a Carbon Makes: H4octapa vs H4C3octapa, Ligands for In-111 and Lu-177 Radiochemistry (2014) (30)
- Tightening the Hydrophobic Belt: Effects of Backbone and Donor Group Variation on Podand Ligand Complexes of the Lanthanides (1998) (30)
- IN VIVO ELECTRON SPIN-ECHO ENVELOPE MODULATION (ESEEM) SPECTROSCOPY : FIRST OBSERVATION OF VANADYL COORDINATION TO PHOSPHATE IN BONE (1999) (29)
- General method for the synthesis of trishydroxamic acids (1992) (29)
- Long-chain rhenium and technetium glucosamine conjugates. (2009) (28)
- Intestinal absorption of trace amounts of aluminium in rats studied with 26aluminium and accelerator mass spectrometry. (1997) (28)
- Selectivity of Potentially Hexadentate Amine Phenols for Ga3+ and In3+ in Aqueous Solution†,‡ (1996) (28)
- Rhenium(V) and technetium(V) complexes of bidentate (O,O) monobasic 3-oxy-4-pyronato and -4-pyridinonato ligands. X-ray structures of cis-bromobis(3-methyl-2-oxy-4-pyronato)oxorhenium(V), tetra-n-butylammonium tribromo(3-methyl-2-oxy-4-pyronato)oxorhenate(V), and tetra-n-butylammonium trichloro(3-me (1993) (28)
- Medicinal Inorganic Chemistry Approaches to Passivation and Removal of Aberrant Metal Ions in Disease (2010) (28)
- 1,1′-Disubstituted Ferrocenyl Carbohydrate Chloroquine Conjugates as Potential Antimalarials (2012) (27)
- Functionally Versatile and Highly Stable Chelator for 111In and 177Lu: Proof-of-Principle Prostate-Specific Membrane Antigen Targeting. (2019) (27)
- p-NO2-Bn-H4neunpa and H4neunpa-Trastuzumab: Bifunctional Chelator for Radiometalpharmaceuticals and 111In Immuno-Single Photon Emission Computed Tomography Imaging. (2017) (26)
- Modular Synthesis of 1,2- and 1,1′-Disubstituted Ferrocenyl Carbohydrate Chloroquine and Mefloquine Conjugates as Potential Antimalarial Agents (2012) (26)
- Iron(III)-binding of the anticancer agents doxorubicin and vosaroxin. (2015) (26)
- 1,2-disubstituted ferrocenyl carbohydrate chloroquine conjugates as potential antimalarial agents. (2012) (26)
- Dipicolinate Complexes of Gallium(III) and Lanthanum(III). (2016) (25)
- Exoclathrate Al(C7H8NO2)3.cntdot.12H2O. A facial geometry imposed by extensive hydrogen bonding with the ice I structure (1987) (25)
- Radiopharmaceuticals for diagnosis in nuclear medicine: a short review (2019) (25)
- Synthesis and Coordination Chemistry of Hexadentate Picolinic Acid Based Bispidine Ligands. (2016) (25)
- Cationic Lanthanide Complexes of N,N'-Bis(2-pyridylmethyl)ethylenediamine-N,N'-diacetic Acid (H(2)bped). (1997) (24)
- Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225Ac (2019) (24)
- Exploring the multifunctionality of thioflavin- and deferiprone-based molecules as acetylcholinesterase inhibitors for potential application in Alzheimer's disease. (2013) (24)
- Lanthanide chemistry with (bis[[bis(carboxymethyl)amino]methyl]phosphinate: what does an extra phosphinate group do to EDTA? (2001) (24)
- Effect of Pyridyl Donors in the Chelation of Aluminum(III), Gallium(III), and Indium(III). (1997) (24)
- Synthesis and characterization of a pentadentate Schiff base N3O2 ligand and its neutral technetium(V) complex. X-ray structure of {N,N'-3-azapentane-1,5-diylbis(3-(1-iminoethyl)-6-methyl-2H-pyran-2,4(3H)-dionato)(3-)-O,O',N,N',N''}oxotechnetium(V) (1991) (23)
- 225Ac-H4py4pa for Targeted-Alpha-Therapy. (2020) (23)
- A survey of reducing agents for the synthesis of tetraphenylarsonium oxotechnetiumbis(ethanedithiolate) from [99Tc] pertechnetate in aqueous solution. (1980) (23)
- The Aqueous Coordination Chemistry of Aluminum (1993) (23)
- Complexation of iron with the orally active decorporation drug L1 (3-hydroxy-1,2-dimethyl-4-pyridinone). (1992) (22)
- Glucosamine conjugates bearing N,N,O-donors: potential imaging agents utilizing the [M(CO)3]+ core (M = Re, Tc). (2009) (22)
- H4octox: Versatile Bimodal Octadentate Acyclic Chelating Ligand for Medicinal Inorganic Chemistry. (2018) (22)
- Complexation of the potentially heptadentate ligand H3dha3tren with lanthanides: architecture of a [Nd(NO3)3(H3dha3tren)]n polymer with profuse modes of nitrate coordination (1995) (21)
- Molecular architectures for trimetallic d/f/d complexes: magnetic studies of a LnCu2 core. (2008) (21)
- Cationic technetium and rhenium complexes with pendant carbohydrates. (2010) (21)
- Nitroimidazole-Containing H2dedpa and H2CHXdedpa Derivatives as Potential PET Imaging Agents of Hypoxia with (68)Ga. (2015) (21)
- Physical and structural studies of N-carboxymethyl- and N-(p-methoxyphenyl)-3-hydroxy-2-methyl-4-pyridinone (1992) (21)
- In vivo study and thermodynamic investigation of two lanthanum complexes, La(dpp)3 and La(XT), for the treatment of bone resorption disorders† †Electronic supplementary information (ESI) available: Speciation diagrams for metal–ligand complexes (Fig. S1 and S3), ITC analysis of H5XT-hydroxyapatite t (2015) (21)
- In silico to in vitro screening of hydroxypyridinones as acetylcholinesterase inhibitors. (2016) (20)
- Metal chelation with natural products: isomaltol complexes of aluminum, gallium, and indium (1989) (20)
- Complexation of gallium(III) by 2-hydroxynicotinic acid and 3-hydroxypicolinic acid in aqueous solution (1998) (20)
- Hexadentate N3O3 amine phenol ligands for Group 13 metal ions: evidence for intrastrand and interstrand hydrogen-bonds in polydentate tripodal amine phenols (1993) (20)
- Thioflavin-based molecular probes for application in Alzheimer's disease: from in silico to in vitro models. (2015) (20)
- H2hox: Dual-Channel Oxine-Derived Acyclic Chelating Ligand for 68Ga Radiopharmaceuticals. (2018) (20)
- 1-n-Propyl- and 1-n-butyl-3-hydroxy-2-methyl-4-pyridinone complexes of group 13 (IIIA) metal ions (1991) (19)
- Rhenium and technetium complexes from pentadentate (N3O2) and tetradentate (N2O2) Schiff base ligands (1995) (19)
- A comparative evaluation of the chelators H4octapa and CHX-A″-DTPA with the therapeutic radiometal (90)Y. (2016) (19)
- Improved separation of the curcuminoids, syntheses of their rare earth complexes, and studies of potential antiosteoporotic activity. (2014) (19)
- Biological Imaging with Medium-Sensitive Bichromatic Flexible Fluorescent Dyes. (2017) (19)
- One to chelate them all: investigation of a versatile, bifunctional chelator for 64Cu, 99mTc, Re and Co. (2011) (18)
- Discovery of a Copper-Based Mcl-1 Inhibitor as an Effective Antitumor Agent. (2020) (18)
- Gallium(iii) and iron(iii) complexes of quinolone antimicrobials. (2016) (17)
- Synthesis and solution studies of the complexes of pyrone analogue ligands with vanadium(IV) and vanadium(V) (2002) (17)
- Effects of bis(maltolato)oxovanadium(IV) are distinct from food restriction in STZ-diabetic rats. (1997) (17)
- The preparation, characterization, and crystal and molecular structure of oxobis(ethan-1,2-dithiolato-S,µS′)technetium(V)oxo(ethan- 1,2-dithiolato-S,S′)technetium(V) [(TcO)2(SCH2CH2S)3]. A Tc(V) compound containing metal—sulfur—metal bridges (1985) (17)
- 55Cobalt complexes with pendant carbohydrates as potential PET imaging agents. (2007) (17)
- Modular syntheses of H₄octapa and H₂dedpa, and yttrium coordination chemistry relevant to ⁸⁶Y/⁹⁰Y radiopharmaceuticals. (2014) (17)
- 3-Hydroxy-4-pyridinone derivatives as metal ion and amyloid binding agents. (2014) (17)
- In vitro and in vivo anti-tumor activity of two gold(III) complexes with isoquinoline derivatives as ligands. (2019) (17)
- Structure of yttrium octachloroditechnetate nonahydrate (1982) (17)
- Pyridine-tert-nitrogen-phenol ligands: N,N,O-Type tripodal chelates for the [M(CO)3]+ core (M = Re, Tc). (2008) (16)
- Synthesis and Solution Studies of the Complexes of Trivalent Lanthanides with the Tetraazamacrocycle TETA-(PO)2. (2002) (16)
- Mononuclear to Tetranuclear Structural Transformation in Vanadyl Complexes of 3-Hydroxypyridine-2-carboxylic Acid (H2hpic) (2002) (16)
- Synthesis and in vitro anticancer activity of ferrocenyl-aminoquinoline-carboxamide conjugates (2012) (16)
- Coordination chemistry of P, O-bidentate phosphinophenolates with Ga3+ and In3+. (2005) (16)
- Field desorption mass spectrometry of complex anions containing rhenium and technetium (1979) (15)
- Discovery of β-carboline copper(II) complexes as Mcl-1 inhibitor and in vitro and in vivo activity in cancer models. (2019) (15)
- Synthesis, characterization, and evaluation of the antimicrobial potential of copper(II) coordination complexes with quinolone and p-xylenyl-linked quinolone ligands. (2016) (15)
- Chemical and Pharmacological Studies of a New Class of Antidiabetic Vanadium Complexes (1998) (15)
- H4octapa: synthesis, solution equilibria and complexes with useful radiopharmaceutical metal ions. (2017) (15)
- Seven-coordinate [ReVON4X2]+ complexes (X = O and Cl). (2000) (15)
- Harnessing the bone-seeking ability of Ca(II)-like metal ions in the treatment of metastatic cancer and resorption disorders. (2016) (14)
- 3-Hydroxy-4-pyridinone derivatives designed for fluorescence studies to determine interaction with amyloid protein as well as cell permeability. (2015) (14)
- Cationic iron(III) complex with a hexadentate N2,N'2',O2-aminopyridylphenolate ligand (1999) (14)
- Oxobis(2,4-pentanedionato)vanadium(IV), a Redetermination (1995) (14)
- [nat/44Sc(pypa)]-: Thermodynamic Stability, Radiolabeling, and Biodistribution of a Prostate-Specific-Membrane-Antigen-Targeting Conjugate. (2020) (13)
- Pharmacokinetics of aluminum 3-hydroxypyridin-4-one complexes: implications for aluminum redistribution subsequent to chelation therapy. (1994) (12)
- Evaluation of the Tetrakis(3-Hydroxy-4-Pyridinone) Ligand THPN with Zirconium(IV): Thermodynamic Solution Studies, Bifunctionalization, and in Vivo Assessment of Macromolecular 89Zr-THPN-Conjugates. (2019) (12)
- A Neutral Water-Soluble Aluminum Complex of Neurological Interest. (1986) (12)
- Octadentate Oxine-Armed Bispidine Ligand for Radiopharmaceutical Chemistry. (2019) (12)
- VO2+–hydroxyapatite complexes as models for vanadyl coordination to phosphate in bone (2013) (11)
- Chemistry of re with N,N'-bis(2-pyridylmethyl)ethylenediamine (H2pmen): hydrolysis, dehydrogenation, and ternary complexes. (2001) (11)
- Chelation in One Fell Swoop: Optimizing Ligands for Smaller Radiometal Ions. (2020) (11)
- Highly Symmetric Group 13 Metal−Phosphinato Complexes: Multinuclear NMR (27Al,31P,71Ga) Determination of Stability Constants at Low pH (1996) (11)
- Harnessing α-Emitting Radionuclides for Therapy: Radiolabeling Method Review (2021) (11)
- Design and synthesis of multidentate 2-(2′-hydroxyphenyl)-2-thiazolines for biomedical application (1992) (11)
- 99m‐Technetium Carbohydrate Conjugates as Potential Agents in Molecular Imaging (2009) (11)
- Potential 67Ga radiopharmaceuticals for myocardial imaging: tris(1-aryl-3-hydroxy-2-methyl-4-pyridinonato)gallium(III) complexes. (1992) (10)
- Thorium chelators for Targeted Alpha Therapy: Rapid chelation of thorium-226. (2020) (10)
- Synthesis, characterization, and cytotoxicity studies of Cu(II), Zn(II), and Fe(III) complexes of N-derivatized 3-hydroxy-4-pyridiones. (2014) (10)
- Chronic glucose-lowering effects of rosiglitazone and bis(ethylmaltolato)oxovanadium(IV) in ZDF rats. (2003) (10)
- Evaluation of H2CHXdedpa, H2dedpa- and H2CHXdedpa-N,N'-propyl-2-NI ligands for (64)Cu(ii) radiopharmaceuticals. (2016) (10)
- In vivo coordination chemistry and biolocalization of Bis(ligand)orovanadium(IV)complexes for diabetes treatment (2005) (10)
- H2CHXhox: Rigid Cyclohexane-Reinforced Nonmacrocyclic Chelating Ligand for [nat/67/68Ga]Ga3. (2020) (10)
- The Chemistry of Inorganic Nuclides (86Y, 68Ga, 64Cu, 89Zr, 124I) (2014) (9)
- Chemical Promiscuity of Non-Macrocyclic Multidentate Chelating Ligands for Radiometal Ions: H4neunpa-NH2 vs H4noneunpa. (2021) (9)
- Potential 99mTc radiopharmaceuticals for renal imaging: tris(N-substituted-3-hydroxy-2-methyl-4-pyridinonato)technetium(IV) cations. (1993) (9)
- Design, synthesis, and imaging of small amphiphilic rhenium and (99m)technetium tricarbonyl complexes. (2009) (9)
- Tripodal trisamides based on nicotinic and picolinic acid derivatives (1998) (9)
- Theoretical studies of the tautomers of pyridinethiones. (2008) (9)
- Vanadium-Containing Insulin Biomimetic Drugs (1999) (9)
- Biolocalization and in vivo coordination chemistry of vanadium pharmaceuticals (2003) (8)
- A simple method to perform a liquid diffusion crystallization (1985) (8)
- Recent Advances in Asialoglycoprotein Receptor and Glycyrrhetinic Acid Receptor-Mediated and/or pH Responsive Hepatocellular Carcinoma-Targeted Drug Delivery. (2020) (8)
- Characterization of Tris(N-substituted-2-methyl-3-hydroxy-4-pyridinonato)technetium(IV) Cations (1994) (8)
- Acid–base and metal ion-binding properties of diaminopropyl D-glucopyranoside and diaminopropyl D-mannopyranoside compounds in aqueous solution (2000) (8)
- Structural studies of organoboron compounds. XXV. Synthesis and structure of (maltolato)diphenylboron (1987) (8)
- Complexes of phosphine-phenolate ligands with the [Re=O]3+ and [Re(HNNC5H4N)(NNC5H4N)] 2+ cores (2001) (7)
- Di- and Trivalent Metal-Ion Solution Studies with the Phosphinate-Containing Heterocycle DEDA-(PO). (2017) (7)
- Werner Coordination Chemistry and Neurodegeneration (2013) (7)
- RHENIUM COMPLEXES OF P,P,P',P'-TETRAKIS-(O-HYDROXYPHENYL)DIPHOSPHINOETHANE (1996) (7)
- La(iii) biodistribution profiles from intravenous and oral dosing of two lanthanum complexes, La(dpp)3 and La(XT), and evaluation as treatments for bone resorption disorders. (2017) (7)
- Phosphonate Chelators for Medicinal Metal Ions. (2021) (6)
- Preparation of 2- and 4-substituted 3-hydroxy-5-methylfurans and the aluminum and gallium complexes of 3-hydroxy-5-methyl-2-(N-methylformamido)furan (1994) (6)
- Pharmacokinetics and distribution of tris(maltolato)aluminum(III) into the central nervous system. (1994) (6)
- Novel "bi-modal" H2dedpa derivatives for radio- and fluorescence imaging. (2016) (6)
- Active oxygen species formation in synaptosomes exposed to an aluminum chelator. (1998) (5)
- One-pot synthesis of N-substituted-3-hydroxy-4-pyridinone chelate complexes of aluminum, gallium, and indium (1989) (5)
- Proton- and lanthanide-coordinating properties of the tetraaza macrocycle (EDDA-KA)2 in aqueous solution (2001) (5)
- Glypican-3–Targeted 227Th α-Therapy Reduces Tumor Burden in an Orthotopic Xenograft Murine Model of Hepatocellular Carcinoma (2021) (5)
- Lanthanide(III) and group 13 metal ion complexes of tripodal amino phosphinate ligands. (2006) (4)
- mer-Tris[2-(5-bromo-2-hydroxyphenyl)-2-oxazolinato]aluminium(III) methanol solvate (1994) (4)
- Aluminum and Gallium Compounds of 3-Hydroxy-4-pyridinones: Synthesis, Characterization, and Crystallography of Biologically Active Complexes with Unusual Hydrogen Bonding. (1988) (4)
- Peptide and Small Molecule Inhibitors Targeting Myeloid Cell Leukemia 1 (Mcl-1) as Novel Antitumor Agents. (2020) (4)
- [nat/89Zr][Zr(pypa)]: Thermodynamically Stable and Kinetically Inert Binary Nonadentate Complex for Radiopharmaceutical Applications. (2021) (4)
- Structural studies of organoboron compounds. XXVII. (3-Hydroxy-2-methyl-4-pyridinonato)diphenylboron and (3-hydroxy-1,2-dimethyl-4-pyridinonato)diphenylboron (1988) (4)
- Synthesis and characterization of lipophilic cationic Ga(III) complexes based on the H2CHXdedpa and H2dedpa ligands and their 67/68Ga radiolabeling studies (2016) (4)
- One and Two Dimensional Pulsed Electron Paramagnetic Resonance Studies of in vivo Vanadyl Coordination in Rat Kidney (2003) (4)
- Vanadium compounds as possible insulin modifiers (1999) (3)
- [ReO(N2O2)X] complexes: "4 + 1"? (2001) (3)
- Getting a lead on Pb2+-amide chelators for 203/212Pb radiopharmaceuticals. (2021) (3)
- Coordination chemistry of [Y(pypa)]- and comparison immuno-PET imaging of [44Sc]Sc- and [86Y]Y-pypa-phenyl-TRC105. (2020) (3)
- Structural studies of organoboron compounds. XLI. (3-Hydroxy-2-methyl-1-(p-tolyl)-4-pyridinonato)diphenylboron (1990) (3)
- H4HBEDpa: Octadentate Chelate after A. E. Martell. (2021) (3)
- H2pyhox - Octadentate Bis(pyridyloxine). (2021) (3)
- Inorganic radiopharmaceutical chemistry of oxine. (2021) (3)
- Frontiers in radionuclide imaging and therapy, a chemical journey from naturally radioactive elements to targeted theranostic agents. (2017) (3)
- Main group (IIIA or 13) complexes of benzohydroxamic acid and the crystal structure of tris(benzohydroxamato)indium(III) (1988) (3)
- High denticity oxinate-linear-backbone chelating ligand for diagnostic radiometal ions [111In]In3+ and [89Zr]Zr4. (2021) (3)
- Complexation of Ni2+ and Cu2+ by tripodal amine phenol ligands in aqueous solution† (1998) (3)
- Design and Synthesis of Multidentate 2‐(2′‐Hydroxyphenyl)‐2‐ thiazolines for Biomedical Application. (1992) (3)
- The Exoclathrate Al(C7H8NO2)3·12 H2O. A Facial Geometry Imposed by Extensive Hydrogen Bonding with the Ice I Structure. (1987) (2)
- H2ampa─Versatile Chelator for [203Pb]Pb2+, [213Bi]Bi3+, and [225Ac]Ac3. (2022) (2)
- Neutral Water-Soluble Post-Transition-Metal Chelate Complexes of Medical Interest: Aluminum and Gallium Tris(3-hydroxy-4-pyronates). (1987) (2)
- Matching Chelators to Radiometals for Radiopharmaceuticals (2014) (2)
- Improved separation scheme for 44Sc produced by irradiation of natCa targets with 12.8 MeV protons. (2021) (2)
- Acyclic chelating ligands for PET imaging of tumor hypoxia with Ga-68 (2014) (2)
- Trastuzumab-conjugated oxine-based ligand for [89Zr]Zr4+ immunoPET. (2022) (2)
- H4picoopa─Robust Chelate for 225Ac/111In Theranostics. (2022) (2)
- Evaluation of La(XT), a novel lanthanide compound, in an OVX rat model of osteoporosis (2021) (2)
- Metal ion size profoundly affects H3glyox chelate chemistry (2021) (2)
- Polydentate Ligand Chemistry of Group 13 Metals: Effects of the Size and Donor Selectivity of Metal Ions on the Structures and Properties of Aluminum, Gallium, and Indium Complexes with Potentially Heptadentate (N4O3) Amine Phenol Ligands. (1993) (1)
- H3TPAN-Triazole-Bn-NH2: Tripicolinate Clicked-Bifunctional Chelate for [225Ac]/[111In] Theranostics. (2022) (1)
- Crystal structure of (2-hydroxy-5-methylphenyl)diphenylphosphineoxide, (C6H5)2P(O)(CH3C6H3OH) (2000) (1)
- Neutral Water-Soluble Indium Complexes of 3-Hydroxy-4-pyrones and 3-Hydroxy-4-pyridinones. (1989) (1)
- tBu4octapa-alkyl-NHS for metalloradiopeptide preparation. (2020) (1)
- Selectivity among, and aggregation of, lanthanide ions (1997) (1)
- (Acetonitrile)[N,N‐bis(3‐aminopropyl)‐1,3‐propanediamine‐N,N',N'',N''']copper(II) Diperchlorate (1996) (1)
- phospa-Trastuzumab : Bifunctional Methylenephosphonate-based Chelator with 89 Zr , 111 In and 177 (2014) (1)
- New Bifunctional Chelators for 225Ac and 227Th Radioimmunotherapy (2019) (1)
- H4octapa-trastuzumab: An acyclic chelator-immunoconjugate with superior properties to DOTA for In-111/Lu-177 imaging and therapy (2013) (1)
- Synthesis and characterization of a pentadentate Schiff base N[sub 3]O[sub 2] ligand and its neutral technetium(V) complex. X-ray structure of (N,N[prime]-3-azapentane-1,5-diylbis(3-(1-iminoethyl)-6-methyl-2H-pyran-2,4(3H)-dionato)(3-)-O,O[prime],N,N[prime],N[double prime])oxotechnetium(V) (1991) (1)
- Toward 68Ga and 64Cu Positron Emission Tomography Probes: Is H2dedpa-N,N'-pram the Missing Link for dedpa Conjugation? (2023) (1)
- Rapid Thermodynamically Stable Complex Formation of [nat/111In]In3+, [nat/90Y]Y3+, and [nat/177Lu]Lu3+ with H6dappa. (2020) (1)
- Effect of Pyridyl Donors in the Chelation of Aluminum(III), Gallium(III), and Indium(III). (1997) (1)
- Insulin-mimetic vanadium complexes (1997) (1)
- New bifunctional chelators for diagnostic and therapeutic radioisotopes (2019) (1)
- Essential Metal Related Metabolic Disorders (2011) (1)
- Metal Complexes of Maltol and Close Analogues in Medicinal Inorganic Chemistry (2006) (1)
- [213Bi]Bi3+/[111In]In3+-neunpa-cycMSH: Theranostic Radiopharmaceutical Targeting Melanoma─Structural, Radiochemical, and Biological Evaluation. (2022) (1)
- Study of the kinetics of complex formation and in vivo stability of novel radiometal-chelate conjugates for applications in nuclear medicine (2017) (0)
- Alan Davison, FRS. (2016) (0)
- Aluminum and Gallium Complexes of 1-Ethyl-3-hydroxy-2-methyl-4-pyridinone: A New Exoclathrate Matrix. (1989) (0)
- H2CHXhox: Rigid Cyclohexane-Reinforced Nonmacrocyclic Chelating Ligand for [Ga]Ga (2020) (0)
- Solution studies of the insulin-mimetic compound BMOV (1995) (0)
- Bis(amido)bis(oxinate)diamine Ligands for theranostic radiometals. (2022) (0)
- Vanadium compounds as insulin mimetic agents in the treatment of diabetes (1993) (0)
- Radiolabeling and proof-of-principle in vivo studies using actinium-225 produced at TRIUMF’s isotope separation on-line facility (2019) (0)
- Structure of (η‐cyclopentadienyl){(3R*,3aR*)‐5‐5a‐9a‐9b‐η‐3‐methoxy‐5‐trimethylsilyl‐2,3,3a,4,6,7,8,9‐octahydro‐1H‐benz[e]indene}cobalt, [Co(C5H5)(C17H28OSi)] (1985) (0)
- Gallium-67 complexes for myocardial imaging. (1991) (0)
- Optimal ‘hardness’ of non-macrocyclic chelators for [203Pb]Pb2+ radiopharmaceutical applications (2021) (0)
- Triaza-18-crown-6 macrocyclic chelators for the [203:212Pb]Pb2+ theranostic pair (2022) (0)
- Design of Targeting Ligands in Medicinal Inorganic Chemistry (2006) (0)
- Design , Synthesis , and Imaging of Small Amphiphilic Rhenium and 99 mTechnetium Tricarbonyl Complexes (2009) (0)
- Retraction of "Synthesis and Solution Studies of the Complexes of Trivalent Lanthanides with the Tetraazamacrocycle TETA-(PO)2". (2017) (0)
- [N,N'-Bis(2-pyridylmethyl)ethylenediaminediacetato]cobalt(III) Perchlorate Monohydrate (1998) (0)
- trans‐Tetrachlorobis(triphenylphosphine‐P)rhenium(IV)–mer‐trans‐Trichlorooxobis(triphenylphosphine‐P)rhenium(V) (0.86/0.14) (1996) (0)
- Equilibrium and Structural Studies of Silicon(IV) and Aluminum(III) in Aqueous Solution. Part 18. Complexation of Aluminum with N-Substituted 3-Hydroxy-4-pyridinones. (1989) (0)
- Kinetic studies of Al(III) and Ga(III) uptake by transferrin. (1991) (0)
- H4octapa vs H4C3octapa: The difference of a single carbon atom (2014) (0)
- Monocationic Ga and in complexes with modified amine pheols which possess a 3-dimensional N-2N2O-2 donor atom cavity (1995) (0)
- Synthesis and solution studies of the complexes of trivalent lanthanides with the tetraazamacrocycle TETA-(PO)(2). (2002) (0)
- Production of emerging theranostic radionuclides at TRIUMF (2022) (0)
- Aluminum bioinorganic chemistry (1989) (0)
- Structural Studies of Organoboron Compounds. Part 41. (3-Hydroxy-2- methyl-1-(p-tolyl)-4-pyridinonato)diphenylboron. (1991) (0)
- Dalton transactions: providing the best services. (2008) (0)
- TRIHOPO: 1,2-HOPO-based macrocyclic chelator for 225Ac, 227Th, and 89Zr (2022) (0)
- Evaluation of [227Th]thorium chelation of hydroxypyridinone- and picolinic acid-containing ligands to simulate 226Th chelation (2019) (0)
- Abstract 928: Glypican-3 targeted thorium-227 alpha therapy reduces tumor burden in an orthotopic xenograft model of hepatocellular carcinoma (2021) (0)
- Dalton Transactions 40th Anniversary (2011) (0)
- 2008: a record year for Dalton Transactions! (2009) (0)
- Acyclic chelators for PET imaging of hypoxia with 68Ga (2013) (0)
- Announcment: 31st International Conference on Coordination Chemistry (1995) (0)
- Toward Bifunctional Chelators for Thallium-201 for Use in Nuclear Medicine (2022) (0)
- Stan Kirschner―An appreciation (2009) (0)
- Acyclic chelators as potential PET imaging agents of hypoxia with 68Ga (2014) (0)
- 1-Carboxymethyl-3-hydroxy-2-methyl-4(1H)-pyridinone (monoclinic form 2) (1994) (0)
- General Method for the Synthesis of Trishydroxamic Acids. (1992) (0)
- Metallodrugs for therapy and imaging : investigation of their mechanism of action (2018) (0)
- Design of New Oxovanadium (IV) Complexes for Treatment of Diabetes. Biovailability, Speciation, and Tissue Targeting Considerations (2002) (0)
- Proposal to the ISOLDE and Neutron Time-of-Flight Committee Study of the kinetics of complex formation and in vivo stability of novel radiometal-chelate conjugates for applications in nuclear medicine . 11 January 2017 (2017) (0)
- Development of small amphiphilic Rhenium and Tc-99m tricarbonyl complexes (2009) (0)
- A highly stable functionalizable chelator for 67Ga/68Ga (2010) (0)
- Lanthanoid Complexes of Potentially Heptadentate Ligands Including the Structure of (Tris(3-aza-4-methylhept-4-ene-6-on-1-yl)amine)tris(nitrato)gadolinium(III). (1989) (0)
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