Christian Gieger
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Christian Giegercomputer-science Degrees
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Computer Science
Christian Gieger's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Christian Gieger's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease (2012) (4007)
- Genetic studies of body mass index yield new insights for obesity biology (2015) (3549)
- Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids (2010) (3485)
- Discovery and Refinement of Loci Associated with Lipid Levels (2013) (2475)
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (2010) (2087)
- Genomewide association analysis of coronary artery disease. (2007) (2067)
- Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index (2010) (2011)
- Hundreds of variants clustered in genomic loci and biological pathways affect human height (2010) (1961)
- Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk (2011) (1928)
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes (2012) (1839)
- Defining the role of common variation in the genomic and biological architecture of adult human height (2014) (1805)
- Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis (2010) (1801)
- Genome-Wide Association Study reveals genetic risk underlying Parkinson’s disease (2009) (1770)
- Six new loci associated with body mass index highlight a neuronal influence on body weight regulation (2009) (1735)
- A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease (2015) (1567)
- New genetic loci link adipose and insulin biology to body fat distribution (2014) (1227)
- Genome-wide association study identifies eight loci associated with blood pressure (2009) (1225)
- Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index (2010) (1179)
- Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis (2013) (1170)
- Genome-wide association study identifies 74 loci associated with educational attainment (2016) (1114)
- Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps (2018) (1028)
- Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility (2014) (933)
- Human metabolic individuality in biomedical and pharmaceutical research (2011) (929)
- The genetic architecture of type 2 diabetes (2016) (927)
- An atlas of genetic influences on human blood metabolites (2014) (913)
- Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts (2009) (909)
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease (2011) (894)
- GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment (2013) (803)
- Common variants associated with plasma triglycerides and risk for coronary artery disease (2013) (767)
- Identification of seven loci affecting mean telomere length and their association with disease (2013) (761)
- Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways (2012) (758)
- Seven New Loci Associated with Age-Related Macular Degeneration (2013) (741)
- Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries (2018) (735)
- Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans (2015) (724)
- DNA methylation-based measures of biological age: meta-analysis predicting time to death (2016) (699)
- Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum (2008) (691)
- Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior (2010) (688)
- Genome-wide association analyses identify 18 new loci associated with serum urate concentrations (2012) (678)
- DNA methylation and body-mass index: a genome-wide analysis (2014) (664)
- Tobacco Smoking Leads to Extensive Genome-Wide Changes in DNA Methylation (2013) (662)
- Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (659)
- Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions (2007) (657)
- A genome-wide perspective of genetic variation in human metabolism (2010) (639)
- Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity (2016) (634)
- Identification of ten loci associated with height highlights new biological pathways in human growth (2008) (626)
- Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations (2009) (617)
- Novel biomarkers for pre-diabetes identified by metabolomics (2012) (587)
- Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants (2021) (585)
- Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture (2013) (568)
- Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses (2016) (563)
- Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity (2012) (555)
- A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium (2009) (551)
- An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans (2017) (547)
- Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting (2010) (544)
- A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization (2006) (537)
- The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2015) (532)
- Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma (2011) (526)
- Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution (2009) (516)
- Parent-of-origin specific allelic associations among 106 genomic loci for age at menarche (2014) (511)
- KORA-gen--resource for population genetics, controls and a broad spectrum of disease phenotypes. (2005) (506)
- Correlation between Genetic and Geographic Structure in Europe (2008) (485)
- Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies (2010) (477)
- Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels (2011) (476)
- Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA (2016) (471)
- A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke (2009) (466)
- Genome-wide association study of PR interval (2010) (432)
- Exome-wide association study of plasma lipids in >300,000 individuals (2017) (428)
- Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus (2011) (428)
- Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (2017) (428)
- Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways (2010) (425)
- Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure (2011) (424)
- SLC2A9 influences uric acid concentrations with pronounced sex-specific effects (2008) (423)
- New gene functions in megakaryopoiesis and platelet formation (2011) (423)
- Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences (2019) (421)
- Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function (2011) (401)
- Common variants at ten loci modulate the QT interval duration in the QTSCD Study (2009) (401)
- Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
- Connecting genetic risk to disease end points through the human blood plasma proteome (2016) (382)
- Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium (2009) (369)
- Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis (2010) (367)
- Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits (2013) (365)
- Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk (2017) (359)
- Seventy-five genetic loci influencing the human red blood cell (2012) (357)
- Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology (2017) (357)
- Multi-ethnic genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis (2015) (356)
- Genetic fine-mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci (2015) (349)
- Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study. (2015) (347)
- Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2 (2010) (343)
- Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach (2013) (338)
- META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES IDENTIFIES THREE NEW RISK LOCI FOR ATOPIC DERMATITIS (2011) (325)
- Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers (2011) (325)
- Genome-wide association analysis identifies three psoriasis susceptibility loci (2010) (314)
- Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile (2011) (313)
- Sequence variants at CHRNB 3 – CHRNA 6 and CYP 2 A 6 affect smoking behavior (2010) (312)
- Prevalence of refractive error in Europe: the European Eye Epidemiology (E3) Consortium (2015) (312)
- Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair (2015) (308)
- Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis (2017) (308)
- Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci. (2012) (301)
- The impact of low-frequency and rare variants on lipid levels (2015) (300)
- Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus (2008) (289)
- Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation (2015) (285)
- Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke (2008) (284)
- Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. (2012) (282)
- Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism (2015) (276)
- PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome (2008) (269)
- Correction: Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis (2015) (268)
- Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases (2012) (263)
- Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization (2014) (260)
- New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. (2018) (257)
- A catalog of genetic loci associated with kidney function from analyses of a million individuals (2019) (252)
- Genome-wide analysis identifies 12 loci influencing human reproductive behavior (2016) (250)
- High density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis (2014) (250)
- Human serum metabolic profiles are age dependent (2012) (247)
- Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels (2018) (246)
- New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk (2016) (242)
- A genome-wide association study of metabolic traits in human urine (2011) (241)
- Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. (2015) (240)
- Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (228)
- Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption (2014) (224)
- Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci (2011) (224)
- Narcolepsy is strongly associated with the TCR alpha locus (2009) (219)
- Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets (2017) (217)
- Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies (2018) (213)
- Common variants in P2RY11 are associated with narcolepsy (2010) (213)
- Metabolomic markers reveal novel pathways of ageing and early development in human populations (2013) (209)
- ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy (2013) (208)
- Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations (2009) (201)
- Genetic evidence of assortative mating in humans (2017) (199)
- The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis (2013) (199)
- KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference (2016) (198)
- Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci. (2012) (198)
- Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL) (2010) (186)
- Genome-Wide Association Studies of Serum Magnesium, Potassium, and Sodium Concentrations Identify Six Loci Influencing Serum Magnesium Levels (2010) (185)
- Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study (2011) (185)
- Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels (2019) (183)
- Erratum: Narcolepsy is strongly associated with the T-cell receptor alpha locus (2009) (181)
- Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function (2017) (180)
- Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels (2015) (179)
- Gender-specific pathway differences in the human serum metabolome (2015) (178)
- Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits (2013) (177)
- Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease (2018) (175)
- Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection (2014) (173)
- Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1 (2011) (172)
- Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis (2014) (170)
- Genetic variation in metabolic phenotypes: study designs and applications (2012) (166)
- Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease (2014) (163)
- Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes. (2016) (159)
- Genetics (AAGC) (2015). Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. (2015) (157)
- Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis (2017) (156)
- Mining the Unknown: A Systems Approach to Metabolite Identification Combining Genetic and Metabolic Information (2012) (156)
- Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease. (2010) (155)
- Genome-wide association analysis identifies multiple loci related to resting heart rate. (2010) (154)
- Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study (2008) (154)
- DNA Methylation of Lipid-Related Genes Affects Blood Lipid Levels (2015) (153)
- Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2017) (153)
- Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls (2019) (153)
- Genome‐wide association analysis in Primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4 (2013) (153)
- Genetic Regulation of Serum Phytosterol Levels and Risk of Coronary Artery Disease (2010) (151)
- Characterization of whole-genome autosomal differences of DNA methylation between men and women (2015) (151)
- Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. (2014) (150)
- Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk (2019) (150)
- Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways (2012) (150)
- Meta-analyses identify 13 novel loci associated with age at menopause and highlights DNA repair and immune pathways (2011) (149)
- Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels (2016) (147)
- Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error (2018) (147)
- A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study. (2012) (146)
- Loci influencing blood pressure identified using a cardiovascular gene-centric array. (2013) (145)
- Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms (2015) (144)
- Directional dominance on stature and cognition in diverse human populations (2015) (144)
- A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population. (2016) (144)
- Genome-wide association analysis identifies six new loci associated with forced vital capacity (2014) (141)
- IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes (2018) (139)
- The Molecular Genetic Architecture of Self-Employment (2013) (137)
- Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects (2013) (135)
- Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32. (2012) (134)
- A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. (2009) (133)
- Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. (2011) (133)
- Meta-analysis identifies seven susceptibility loci involved in the atopic march (2015) (133)
- Multiethnic Meta-Analysis of Genome-Wide Association Studies in >100 000 Subjects Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular Disease (2013) (133)
- Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations (2013) (130)
- The power of genetic diversity in genome-wide association studies of lipids (2021) (129)
- Adiposity as a cause of cardiovascular disease: a Mendelian randomization study. (2015) (128)
- Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (127)
- On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants. (2008) (126)
- Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23. (2011) (125)
- A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function. (2009) (124)
- Multiple Loci Are Associated with White Blood Cell Phenotypes (2011) (123)
- A genome-wide association study identifies three loci associated with mean platelet volume. (2009) (123)
- Metabolic Profiling Reveals Distinct Variations Linked to Nicotine Consumption in Humans — First Results from the KORA Study (2008) (122)
- Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators. (2010) (122)
- Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes (2015) (121)
- Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney (2017) (121)
- Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms (2014) (120)
- Genome-wide meta-analysis of Psoriatic Arthritis Identifies Susceptibility Locus at REL (2011) (120)
- Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation (2018) (117)
- Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups (2015) (116)
- Common genetic variants associate with serum phosphorus concentration. (2010) (114)
- Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation (2015) (110)
- Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. (2014) (110)
- Genetics of human metabolism: an update (2015) (109)
- Metabolites associate with kidney function decline and incident chronic kidney disease in the general population. (2013) (107)
- Targeting 160 Candidate Genes for Blood Pressure Regulation with a Genome-Wide Genotyping Array (2009) (106)
- Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation (2016) (104)
- Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies (2018) (104)
- Serum metabolite concentrations and decreased GFR in the general population. (2012) (104)
- Telomere length in circulating leukocytes is associated with lung function and disease (2013) (103)
- Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes (2015) (103)
- On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies (2012) (103)
- Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon (2014) (102)
- Genome-Wide Association Analysis of High-Density Lipoprotein Cholesterol in the Population-Based KORA Study Sheds New Light on Intergenic Regions (2008) (101)
- Long-term exposure to air pollution is associated with biological aging (2016) (100)
- A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. (2018) (100)
- Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease. (2019) (99)
- Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. (2012) (99)
- Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error (2016) (98)
- Body Fat Free Mass Is Associated with the Serum Metabolite Profile in a Population-Based Study (2012) (98)
- An integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methylation associated with atopic dermatitis. (2014) (98)
- 52 Genetic Loci Influencing Myocardial Mass. (2016) (98)
- Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies. (2018) (96)
- 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function (2017) (95)
- Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy. (2011) (93)
- Association of Novel Genetic Loci With Circulating Fibrinogen Levels: A Genome-Wide Association Study in 6 Population-Based Cohorts (2009) (93)
- Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids (2019) (93)
- Burden Analysis of Rare Microdeletions Suggests a Strong Impact of Neurodevelopmental Genes in Genetic Generalised Epilepsies (2015) (89)
- Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease (2019) (89)
- Replication of restless legs syndrome loci in three European populations (2009) (88)
- Metabolomic Identification of a Novel Pathway of Blood Pressure Regulation Involving Hexadecanedioate (2015) (88)
- Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation (2020) (88)
- Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk. (2015) (88)
- Eight blood pressure loci identified by genome-wide association study of 34,433 people of European ancestry (2009) (88)
- IL6 Gene Promoter Polymorphisms and Type 2 Diabetes (2006) (87)
- Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality (2015) (87)
- Analyzing Illumina Gene Expression Microarray Data from Different Tissues: Methodological Aspects of Data Analysis in the MetaXpress Consortium (2012) (86)
- Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis (2018) (81)
- The Human Blood Metabolome-Transcriptome Interface (2015) (81)
- Variants of the PPARG, IGF2BP2, CDKAL1, HHEX, and TCF7L2 genes confer risk of type 2 diabetes independently of BMI in the German KORA studies. (2008) (80)
- Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals (2022) (80)
- Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium (2016) (80)
- Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease (2017) (78)
- Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels. (2011) (78)
- Association between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 Study (2016) (78)
- Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. (2019) (77)
- Association of Atopic Dermatitis with Cardiovascular Risk Factors and Diseases. (2017) (76)
- Narcolepsy is strongly associated with the T-cell receptor alpha locus (vol 41, pg 708, 2009) (2014) (76)
- Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder (2012) (76)
- Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma (2013) (75)
- Discovery and fine mapping of serum protein loci through transethnic meta-analysis. (2012) (75)
- Recessive mutations in the α3 (VI) collagen gene COL6A3 cause early-onset isolated dystonia. (2015) (74)
- Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length (2020) (74)
- Genome-wide methylation data mirror ancestry information (2016) (74)
- Joint analysis of individual participants’ data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index (2009) (74)
- IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci (2010) (72)
- Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation (2015) (72)
- A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3. (2011) (71)
- Variants in RUNX3 contribute to susceptibility to psoriatic arthritis, exhibiting further common ground with ankylosing spondylitis. (2013) (71)
- Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells (2015) (69)
- Genetic Evidence for PLASMINOGEN as a Shared Genetic Risk Factor of Coronary Artery Disease and Periodontitis (2015) (69)
- Associations of autozygosity with a broad range of human phenotypes (2019) (68)
- A sequence variant in ZFHX 3 on 16 q 22 associates with atrial fibrillation and ischemic stroke (2009) (68)
- Risk gene variants for nicotine dependence in the CHRNA5–CHRNA3–CHRNB4 cluster are associated with cognitive performance (2010) (68)
- A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms[S] (2017) (67)
- Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. (2012) (67)
- Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error. (2013) (67)
- Long term conservation of human metabolic phenotypes and link to heritability (2014) (65)
- Genome-wide association study identifies 48 common genetic variants associated with handedness (2019) (65)
- European lactase persistence genotype shows evidence of association with increase in body mass index (2009) (65)
- miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis. (2017) (65)
- Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity (2019) (65)
- A saturated map of common genetic variants associated with human height (2022) (65)
- The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies. (2019) (64)
- The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers (2017) (64)
- Genetic Predictors of Fibrin D-Dimer Levels in Healthy Adults (2011) (63)
- Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes (2016) (63)
- Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors (2015) (62)
- MEIS1 and BTBD9: genetic association with restless leg syndrome in end stage renal disease (2011) (62)
- Posttraumatic Stress Disorder and Not Depression Is Associated with Shorter Leukocyte Telomere Length: Findings from 3,000 Participants in the Population-Based KORA F4 Study (2013) (60)
- An epigenome-wide association study meta-analysis of educational attainment (2017) (60)
- Metabolomics approach reveals effects of antihypertensives and lipid-lowering drugs on the human metabolism (2014) (59)
- A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape (2016) (59)
- 16p11.2 600 kb Duplications confer risk for typical and atypical Rolandic epilepsy. (2014) (58)
- Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (2020) (58)
- Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. (2013) (57)
- Impact of common regulatory single-nucleotide variants on gene expression profiles in whole blood (2012) (55)
- Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps (2018) (55)
- Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures (2015) (53)
- JC Polyomavirus Infection Is Strongly Controlled by Human Leucocyte Antigen Class II Variants (2014) (52)
- Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk. (2011) (52)
- Heme Oxygenase-1 Gene Promoter Microsatellite Polymorphism Is Associated With Progressive Atherosclerosis and Incident Cardiovascular Disease (2015) (50)
- Targeted resequencing and systematic in vivo functional testing identifies rare variants in MEIS1 as significant contributors to restless legs syndrome. (2014) (50)
- Multi-omic signature of body weight change: results from a population-based cohort study (2015) (50)
- Genome-Wide Association Study to Identify Common Variants Associated with Brachial Circumference: A Meta-Analysis of 14 Cohorts (2012) (50)
- A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction (2017) (49)
- Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging (2021) (48)
- Niemann-Pick C Disease Gene Mutations and Age-Related Neurodegenerative Disorders (2013) (48)
- Genome-Wide Association Study of L-Arginine and Dimethylarginines Reveals Novel Metabolic Pathway for Symmetric Dimethylarginine (2014) (48)
- Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits (2020) (47)
- Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration (2019) (47)
- Pseudoexfoliation syndrome-associated genetic variants affect transcription factor binding and alternative splicing of LOXL1 (2017) (47)
- Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns (2018) (47)
- Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. (2012) (46)
- Metabotyping and its application in targeted nutrition: an overview (2017) (46)
- Rare sequence variants in ANO3 and GNAL in a primary torsion dystonia series and controls (2014) (46)
- Genome-Wide Meta-Analysis of Myopia and Hyperopia Provides Evidence for Replication of 11 Loci (2014) (45)
- Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway (2017) (44)
- Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues (2016) (44)
- The role of SCARB2 as susceptibility factor in Parkinson's disease (2013) (44)
- Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2 (2016) (44)
- DNA mismatch repair gene MSH6 implicated in determining age at natural menopause (2013) (44)
- The Use of Genome-Wide eQTL Associations in Lymphoblastoid Cell Lines to Identify Novel Genetic Pathways Involved in Complex Traits (2011) (44)
- Metabolite profiling reveals new insights into the regulation of serum urate in humans (2013) (44)
- A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk (2017) (43)
- A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1. (2012) (42)
- DYT16 revisited: Exome sequencing identifies PRKRA mutations in a European dystonia family (2014) (42)
- Mapping the Genetic Architecture of Gene Regulation in Whole Blood (2014) (41)
- Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci (2017) (41)
- Genetic Determinants of Circulating Interleukin-1 Receptor Antagonist Levels and Their Association With Glycemic Traits (2014) (40)
- Genome-wide exploration identifies sex-specific genetic effects of alleles upstream NPY to increase the risk of severe periodontitis in men. (2014) (40)
- Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution (2009) (39)
- A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis. (2015) (39)
- Genetic variants in the immunoglobulin heavy chain locus are associated with the IgG index in multiple sclerosis (2013) (38)
- Alcohol consumption is associated with widespread changes in blood DNA methylation: analysis of cross-sectional and longitudinal data (2018) (37)
- Rare variants in β-Amyloid precursor protein (APP) and Parkinson’s disease (2015) (37)
- Defining the genetic control of human blood plasma N-glycome using genome-wide association study (2018) (37)
- Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2016) (37)
- Variants in eukaryotic translation initiation factor 4G1 in sporadic Parkinson’s disease (2012) (36)
- A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms (2017) (35)
- Immune‐Array Analysis in Sporadic Inclusion Body Myositis Reveals HLA–DRB1 Amino Acid Heterogeneity Across the Myositis Spectrum (2017) (35)
- Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts (2020) (35)
- DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning (2018) (34)
- Genetic associations with lipoprotein subfractions provide information on their biological nature. (2012) (34)
- IgG glycosylation and DNA methylation are interconnected with smoking. (2018) (34)
- Impact of long-term storage and freeze-thawing on eight circulating microRNAs in plasma samples (2020) (34)
- A Genome-Wide Screen for Interactions Reveals a New Locus on 4p15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol (2011) (34)
- Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations (2018) (33)
- An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker (2015) (33)
- Dilution of candidates: the case of iron-related genes in restless legs syndrome (2012) (32)
- Genome Wide Meta-analysis Highlights the Role of Genetic Variation in RARRES2 in the Regulation of Circulating Serum Chemerin (2014) (32)
- Increased amino acids levels and the risk of developing of hypertriglyceridemia in a 7-year follow-up (2014) (32)
- Genome-wide meta-analysis of common variant differences between men and women (2012) (31)
- Genome-wide association study identifies a psoriasis susceptibility locus at TRAF 3 IP 2 (2010) (31)
- Common variation in PHACTR 1 is associated with susceptibility to cervical artery dissection (2014) (31)
- Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model (2017) (31)
- Publisher Correction: Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway (2018) (30)
- Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses. (2014) (30)
- Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study (2017) (29)
- Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour (2021) (29)
- Mitochondrial DNA Variants in Obesity (2014) (29)
- Ageing Investigation Using Two-Time-Point Metabolomics Data from KORA and CARLA Studies (2019) (29)
- Meta-Analysis of Genome-Wide Association Studies and Network Analysis-Based Integration with Gene Expression Data Identify New Suggestive Loci and Unravel a Wnt-Centric Network Associated with Dupuytren’s Disease (2016) (29)
- SLC23A1 polymorphism rs6596473 in the vitamin C transporter SVCT1 is associated with aggressive periodontitis. (2014) (29)
- Metabolomics profiling reveals novel markers for leukocyte telomere length (2016) (29)
- Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes (2020) (29)
- The common non-synonymous variant G38S of the KCNE1-(minK)-gene is not associated to QT interval in Central European Caucasians: results from the KORA study. (2007) (29)
- A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. (2019) (28)
- Genome-Wide Association Study Identifies Two Novel Regions at 11p15.5-p13 and 1p31 with Major Impact on Acute-Phase Serum Amyloid A (2010) (28)
- Disentangling the genetics of lean mass. (2019) (28)
- Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor &agr; (2018) (28)
- Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma (2013) (28)
- Novel SCARB2 mutation in action myoclonus-renal failure syndrome and evaluation of SCARB2 mutations in isolated AMRF features (2011) (28)
- Association of variants in the BAT1-NFKBIL1-LTA genomic region with protection against myocardial infarction in Europeans. (2007) (28)
- Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium (2014) (28)
- Genome-Wide Association Analysis of Young Onset Stroke Identifies a Locus on Chromosome 10 q 25 Near HABP 2 (2015) (28)
- Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. (2020) (27)
- Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function (2022) (27)
- Revealing the role of the human blood plasma proteome in obesity using genetic drivers (2021) (27)
- Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. (2014) (27)
- Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation (2018) (26)
- PSEA: Phenotype Set Enrichment Analysis—A New Method for Analysis of Multiple Phenotypes (2012) (26)
- Alterations in Lipid and Inositol Metabolisms in Two Dopaminergic Disorders (2016) (26)
- Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression. (2019) (26)
- Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. (2015) (26)
- Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research (2015) (26)
- Metabolites of milk intake: a metabolomic approach in UK twins with findings replicated in two European cohorts (2016) (26)
- Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population (2019) (26)
- Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays (2011) (26)
- Stroke genetics informs drug discovery and risk prediction across ancestries (2022) (26)
- Epigenetic Link Between Statin Therapy and Type 2 Diabetes (2020) (26)
- Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure (2017) (25)
- Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts (2015) (25)
- Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (2017) (25)
- Associations between thyroid hormones and serum metabolite profiles in an euthyroid population (2013) (25)
- Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults (2018) (25)
- Global variability of the human IgG glycome (2019) (24)
- Common variants in P 2 RY 11 are associated with narcolepsy (2010) (24)
- Association of a variant in the muscarinic acetylcholine receptor 2 gene (CHRM2) with nicotine addiction (2010) (23)
- CONAN: copy number variation analysis software for genome-wide association studies (2010) (23)
- Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants (2014) (23)
- DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures (2021) (23)
- Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1 q 43 , 2 p 16 . 1 , 2 q 22 . 3 and 17 q 21 . 32 (2012) (23)
- Replication study of multiple sclerosis (MS) susceptibility alleles and correlation of DNA-variants with disease features in a cohort of Austrian MS patients (2012) (23)
- Gene–PUFA interactions and obesity risk (2011) (23)
- Nonadditive Effects of Genes in Human Metabolomics (2015) (23)
- A genome-wide association meta-analysis on apolipoprotein A-IV concentrations (2016) (22)
- Genetic Factors Explain a Major Fraction of the 50% Lower Lipoprotein(a) Concentrations in Finns (2018) (22)
- Metabolomic Profiling of Long‐Term Weight Change: Role of Oxidative Stress and Urate Levels in Weight Gain (2017) (22)
- Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas (2017) (22)
- Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study (2016) (22)
- Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses (2016) (22)
- Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations. (2007) (22)
- Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease (2021) (22)
- Rare variants in LRRK1 and Parkinson's disease (2013) (21)
- Genetic architecture of circulating lipid levels (2011) (21)
- Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116)) (2010) (20)
- Erratum: Connecting genetic risk to disease end points through the human blood plasma proteome (2017) (20)
- Effects of statins on the immunoglobulin G glycome. (2017) (20)
- Comparative analysis of plasma metabolomics response to metabolic challenge tests in healthy subjects and influence of the FTO obesity risk allele (2014) (20)
- Evaluation of gene-obesity interaction effects on cholesterol levels: a genetic predisposition score on HDL-cholesterol is modified by obesity. (2012) (20)
- Are Epigenetic Factors Implicated in Chronic Widespread Pain? (2016) (19)
- Rare Variants in PLXNA4 and Parkinson’s Disease (2013) (19)
- On the potential of models for location and scale for genome-wide DNA methylation data (2014) (19)
- Genetic diversity fuels gene discovery for tobacco and alcohol use (2022) (18)
- Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids (2014) (18)
- NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality. (2017) (18)
- Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (17)
- Analysis with the exome array identifies multiple new independent variants in lipid loci. (2016) (17)
- Variant screening of the coding regions of MEIS1 in patients with restless legs syndrome (2011) (17)
- How to link call rate and p‐values for Hardy–Weinberg equilibrium as measures of genome‐wide SNP data quality (2010) (16)
- Epigenetic scores for the circulating proteome as tools for disease prediction (2020) (16)
- Heritability of young‐ and old‐onset ischaemic stroke (2015) (16)
- Machine Learning Approaches Reveal Metabolic Signatures of Incident Chronic Kidney Disease in Individuals With Prediabetes and Type 2 Diabetes (2020) (16)
- Identification of Comprehensive Metabotypes Associated with Cardiometabolic Diseases in the Population‐Based KORA Study (2018) (16)
- Analysis of repeated leukocyte DNA methylation assessments reveals persistent epigenetic alterations after an incident myocardial infarction (2018) (16)
- Validation of standard operating procedures in a multicenter retrospective study to identify -omics biomarkers for chronic low back pain (2017) (15)
- Circulating Metabolites Differentiate Acute Ischemic Stroke from Stroke Mimics (2020) (15)
- Deciphering the Plasma Proteome of Type 2 Diabetes (2020) (15)
- Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis (2011) (15)
- Excess of rare coding variants in PLD3 in late- but not early-onset Alzheimer’s disease (2015) (15)
- Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention (2022) (14)
- ‘Omics’ biomarkers associated with chronic low back pain: protocol of a retrospective longitudinal study (2016) (14)
- Characterization of the metabolic profile associated with serum 25-hydroxyvitamin D: a cross-sectional analysis in population-based data (2016) (14)
- Diastrophic Dysplasia Sulfate Transporter (SLC26A2) Is Expressed in the Adrenal Cortex and Regulates Aldosterone Secretion (2014) (14)
- Genetic analysis of over one million people identifies 535 novel loci for blood pressure (2017) (14)
- Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations. (2007) (14)
- DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis. (2018) (14)
- Identification of Restless Legs Syndrome Genes by Mutational Load Analysis (2019) (14)
- A network-based conditional genetic association analysis of the human metabolome (2018) (14)
- Author Correction: Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease (2018) (14)
- Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects (2016) (14)
- Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles (2013) (13)
- Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2 p 14 and 16 q 12 . 1 (2017) (13)
- RL-SKAT: An Exact and Efficient Score Test for Heritability and Set Tests (2017) (13)
- Replication of fifteen loci involved in human plasma protein N-glycosylation in 4,802 samples from four cohorts. (2020) (13)
- New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries (2018) (12)
- Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing (2020) (12)
- Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes (2017) (12)
- Meta-analyses identify DNA methylation associated with kidney function and damage (2021) (12)
- MTTP variants and body mass index, waist circumference and serum cholesterol level: Association analyses in 7582 participants of the KORA study cohort. (2008) (12)
- A metabolome-wide association study in the general population reveals decreased levels of serum laurylcarnitine in people with depression (2021) (12)
- Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10 p 11 . 23 (2010) (12)
- Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues (2016) (12)
- A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1 (2012) (11)
- A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids (2021) (11)
- Gene Set of Nuclear-Encoded Mitochondrial Regulators Is Enriched for Common Inherited Variation in Obesity (2013) (11)
- Human gene expression sensitivity according to large scale meta-analysis (2009) (11)
- Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (2021) (11)
- Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin (2018) (10)
- DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function (2021) (10)
- An Application of Isotonic Longitudinal Marginal Regression to Monitoring the Healing Process (1999) (10)
- Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche DTU Orbit (05/11/2017) (2014) (10)
- Metabolic syndrome and the plasma proteome: from association to causation (2021) (10)
- An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population (2009) (10)
- Detecting heritable phenotypes without a model using fast permutation testing for heritability and set-tests (2018) (9)
- Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts (2022) (9)
- Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes (2017) (9)
- Correction: Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2017) (9)
- Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus (2020) (9)
- N-glycosylation of immunoglobulin G predicts incident hypertension (2021) (9)
- Epigenome-wide association study of whole blood gene expression in Framingham Heart Study participants provides molecular insight into the potential role of CHRNA5 in cigarette smoking-related lung diseases (2021) (9)
- Multi-ancestry genome-wide gene–sleep interactions identify novel loci for blood pressure (2021) (9)
- The Pharmacogenetic Footprint of ACE Inhibition: A Population-Based Metabolomics Study (2016) (9)
- The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus (2019) (9)
- Correction: Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1 (2011) (9)
- Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes (2021) (9)
- Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19 (2021) (9)
- Plasma Proteomics of Renal Function: A Transethnic Meta-Analysis and Mendelian Randomization Study (2021) (9)
- Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci (2020) (9)
- Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (8)
- Rare coding variants in 35 genes associate with circulating lipid levels – a multi-ancestry analysis of 170,000 exomes (2020) (8)
- Modifying effect of metabotype on diet–diabetes associations (2019) (8)
- Host traits, lifestyle and environment are associated with human skin bacteria (2021) (8)
- The future of text mining in genome-based clinical research (2003) (8)
- Large-scale TUBB4A mutational screening in isolated dystonia and controls. (2015) (8)
- Erratum to: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits : (Nature Genetics, (2018), 50, 10, (1412-1425), 10.1038/s41588-018-0205-x) (2018) (8)
- Correction: Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study (2008) (7)
- Metabolomic Fingerprints in Large Population Cohorts: Impact of Preanalytical Heterogeneity. (2021) (7)
- Neutrophil “plucking” on megakaryocytes drives platelet production and boosts cardiovascular disease (2022) (7)
- Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2016) (7)
- A multimetric approach to analysis of genome-wide association by single markers and composite likelihood (2008) (7)
- Association analysis between the prostaglandin E synthase 2 R298H polymorphism and body mass index in 8079 participants of the KORA study cohort. (2009) (7)
- Non- and semiparametric marginal regression models for ordinal response (1997) (7)
- Pro-arrhythmic effects of elevated branched chain amino acid levels. (2021) (7)
- Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis (2022) (7)
- Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke (2018) (7)
- Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4 (2021) (7)
- Blood DNA methylation provides an accurate biomarker of KMT2B-related dystonia and predicts onset. (2021) (7)
- Chronically elevated branched chain amino acid levels are pro-arrhythmic (2021) (7)
- Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium (2019) (7)
- Cis-epistasis at the LPA locus and risk of cardiovascular diseases (2021) (7)
- Mutational screening of THAP1 in a German population with primary dystonia. (2012) (6)
- Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease (2020) (6)
- Genome-wide association study identifies novel susceptibility loci for KIT D816V positive mastocytosis. (2021) (6)
- Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases (2022) (6)
- Additive, Dynamic and Multiplicative Regression (1995) (6)
- Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences (2019) (6)
- A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids (2021) (6)
- Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries (2018) (6)
- Random glucose GWAS in 493,036 individuals provides insights into diabetes pathophysiology, complications and treatment stratification (2021) (6)
- Erratum: Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci (American Journal of Human Genetics (2012) 90 (410-425)) (2012) (6)
- Polymorphisms in the receptor for GDNF (RET) are not associated with Parkinson's disease in Southern Germany (2010) (6)
- Network reconstruction for trans acting genetic loci using multi-omics data and prior information (2020) (5)
- Identification of risk loci for primary aldosteronism in genome-wide association studies (2022) (5)
- A Systematic Evaluation of Short Tandem Repeats in Lipid Candidate Genes: Riding on the SNP-Wave (2014) (5)
- MEIS 1 and BTBD 9 : genetic association with restless leg syndrome in end stage renal disease (5)
- Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus (2021) (5)
- Erratum: Common variants in P2RY11 are associated with narcolepsy (2011) (5)
- Validation of Candidate Phospholipid Biomarkers of Chronic Kidney Disease in Hyperglycemic Individuals and Their Organ-Specific Exploration in Leptin Receptor-Deficient db/db Mouse (2021) (5)
- Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (2018) (4)
- Network-based metabolite ratios for an improved functional characterization of genome-wide association study results (2016) (4)
- 4th Pediatric Allergy and Asthma Meeting (PAAM) (2016) (4)
- Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease (2018) (4)
- Impact of the pre-examination phase on multicenter metabolomic studies. (2022) (4)
- Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals (2022) (4)
- The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers (2017) (4)
- Blood cis-eQTL Analysis Fails to Identify Novel Association Signals among Sub-Threshold Candidates from Genome-Wide Association Studies in Restless Legs Syndrome (2014) (4)
- Epigenetic scores for the circulating proteome replicate protein-disease predictions as tools for biomarker discovery (2021) (4)
- Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies (2022) (4)
- Genome-wide association study identifies 48 common genetic variants associated with handedness (2020) (4)
- A genomewide association study of smoking relapse in four European population-based samples (2013) (4)
- Genome-wide Association Study Of Plasma Proteins Identifies Putatively Causal Genes, Proteins, And Pathways For Cardiovascular Disease (2017) (4)
- MO048: Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases (2022) (4)
- Association between functional FABP2 promoter haplotypes and body mass index: analyses of 8072 participants of the KORA cohort study. (2009) (3)
- Supplementary Material 7 (2014) (3)
- Genetic Geostatistical Framework for Spatial Analysis of Fine-Scale Genetic Heterogeneity in Modern Populations: Results from the KORA Study (2015) (3)
- Genome-Wide Characterization of a Highly Penetrant Form of Hyperlipoprotein(a)emia Associated With Genetically Elevated Cardiovascular Risk (2022) (3)
- Supplementary Material 5 (2014) (3)
- An epigenome-wide association study of educational attainment (n = 10,767) (2017) (3)
- Genetic variants in the leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12) gene are not associated with T2DM and related parameters in Caucasians (KORA study). (2007) (3)
- Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke (2022) (3)
- Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations (2022) (3)
- Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (3)
- TIGER: technical variation elimination for metabolomics data using ensemble learning architecture (2022) (3)
- Are spirometric lung function indices associated with telomere length of circulating leukocytes (2012) (3)
- Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure (2020) (3)
- Text mining in life sciences (2005) (3)
- Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis (2018) (3)
- Supplementary Material 6 (2014) (3)
- Using common genetic variants to find drugs for common epilepsies (2021) (3)
- Systematic TOR1A non-c.907_909delGAG variant analysis in isolated dystonia and controls. (2016) (3)
- Supplementary Material 3 (2015) (3)
- Triggering of myocardial infarction by heat exposure is modified by medication intake (2022) (3)
- Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (3)
- Host genetic factors related to innate immunity, environmental sensing and cellular functions are associated with human skin microbiota (2022) (2)
- Automatic Scoring and Quality Assessment Using Accuracy Bounds for FP-TDI SNP Genotyping Data (2005) (2)
- Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility (2016) (2)
- A Family and a Genome-Wide Polygenic Risk Score Are Independently Associated With Stroke in a Population-Based Study (2022) (2)
- Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk (2023) (2)
- Abstract 1879: Genetic Variation at Chromosome 1p13.3 Affects Sortilin mRNA Expression, Cellular LDL Uptake and Serum LDL Levels Which Translates to the Risk of Coronary Artery Disease (2009) (2)
- Characterization of whole-genome autosomal differences of DNA methylation between men and women (2015) (2)
- S26.2: Using Text Mining Networks for the Context Specific Interpretation of Gene Expression Data (2004) (2)
- Assessment of the association of exposure to polycyclic aromatic hydrocarbons, oxidative stress, and inflammation: A cross-sectional study in Augsburg, Germany. (2022) (2)
- Diagnostic and Prognostic Metabolites Identified for Joint Symptoms in the KORA Population. (2016) (2)
- Association between a polygenic and family risk score on the prevalence and incidence of myocardial infarction in the KORA-F3 study. (2022) (2)
- Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (2022) (2)
- Abstracts of the WASAD Conference 2017, 14–16 September, Würzburg, Germany (2017) (2)
- The effect of LPA Thr3888Pro on lipoprotein(a) and coronary artery disease is modified by the LPA KIV-2 variant 4925G>A (2022) (2)
- Comparison of genetic risk prediction models to improve prediction of coronary heart disease in two large cohorts of the MONICA/KORA study (2021) (2)
- Cis-epistasis at the LPA locus and risk of coronary artery disease (2019) (2)
- Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney (2017) (2)
- Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids (2019) (2)
- Colocalization analysis of pancreas eQTLs with risk loci from alcoholic and novel non-alcoholic chronic pancreatitis GWAS suggests potential disease causing mechanisms. (2022) (2)
- Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging (2021) (2)
- Clinical studies in CKD (2012) (1)
- On the potential of models for location and scale for genome-wide DNA methylation data (2014) (1)
- Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function (2022) (1)
- Network based conditional genome wide association analysis of human metabolomics (2016) (1)
- Genome-wide association and large scale follow-up identifies 16 novel loci for lung function (2011) (1)
- Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries (2022) (1)
- Abstract 21: Deciphering the Plasma Proteome of Type 2 Diabetes (2020) (1)
- Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry (2022) (1)
- An exact and efficient score test for variance components models (2017) (1)
- A Large Genome-wide Association Study of Glycated Hemoglobin Identifies Ten Common Variants not Mediated Through BMI (2009) (1)
- Biobanken in der genetisch-epidemiologischen Forschung – Beispiel KORA-gen (Biobanks in Genetic-epidemiological Research such as KORA-gen) (2007) (1)
- Publisher Correction: A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids (2021) (1)
- Abstract 1808: Duffy Antigen Receptor for Chemokines (Darc) Polymorphism Regulates Circulating Concentrations of Monocyte Chemoattractant Protein-1 and Other Circulating Inflammatory Mediators (2009) (1)
- pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms (2017) (1)
- Lab methods / biomarkers (2013) (1)
- Discovery and Refinement Supplementary (2015) (1)
- Causal Effects of Adiposity on Cardiovascular Risk Factors (2015) (1)
- Meta-analysis of genome wide association studies on heart rate variability (2011) (1)
- University of Groningen A Genome-Wide Screen for Interactions Reveals a New Locus on 4 p 15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol (2011) (1)
- Supplementary Material 4 (2015) (1)
- Loci influencing blood pressure identified using a cardiovascular gene-centric array (Correction to Ganesh et al. 22 (8): 1663) (2013) (1)
- Genome-wide physical activity interactions in adiposity (2017) (1)
- Genetic Loci In fl uencing Myocardial Mass (2016) (1)
- Human serum metabolic profiles are age dependent: Metabolic profiles associated with age (2012) (1)
- Epigenetic derepression of FKBP5 by aging and stress contributes to NF-ĸB-driven inflammation and cardiovascular risk (2018) (1)
- DNA Methylation scores augment 10-year risk prediction of diabetes (2021) (1)
- Supplementary Material 15 (2013) (1)
- Polymorphisms in the proteasomal subunit alpha4 are not associated with Parkinson's disease (2008) (1)
- Aging- and Stress-Related Epigenetic Disinhibition of FKBP5 Contributes to NF-KB-Driven Inflammation and Cardiovascular Risk (2017) (1)
- Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma (2013) (1)
- A Common Single Nucleotide Polymorphism in the Chromosome 7q22.3 Region, Which Is Frequently Deleted in Myeloid Malignancies, Is Associated with Mean Platelet Volume and Platelet Function in Healthy Individuals (2008) (1)
- Regression Approaches to Rental Guides (1998) (1)
- Are metabolomic markers associated with spirometric lung function indices? Results of the KORAF4 Study (2013) (1)
- Integrative analysis of clinical and epigenetic biomarkers of mortality (2022) (1)
- Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus (2020) (1)
- Validation of the 30-Year Framingham Risk Score in a German Population-Based Cohort (2022) (1)
- The role of adiposity in cardiometabolic traits (2013) (1)
- Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function (2021) (1)
- The kringle IV type 2 domain variant 4925G>A causes the elusive association signal of the LPA pentanucleotide repeat (2022) (1)
- Erratum: Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height ((The American Journal of Human Genetics (2010) 88 (6-18)) (2012) (1)
- Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity (2019) (1)
- First mitochondrial genome-wide association study with metabolomics (2021) (1)
- Development and validation of DNA methylation scores in two European cohorts augment 10-year risk prediction of type 2 diabetes (2023) (1)
- Abstract 2923: Association Mapping Of QT-interval In a 500k Genome-wide Scan: Confirmation Of NOS1AP And Identification Of A Spectrum Of Additional QTLs (2007) (1)
- Supplementary Material 9 (2013) (1)
- Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile (2019) (1)
- Transcription factor binding site analysis. (2015) (1)
- Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids (2014) (1)
- Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (2021) (1)
- Gender-specific pathway differences in the human serum metabolome (2015) (0)
- Associations between thyroid hormones and serum metabolite profiles in an euthyroid population (2013) (0)
- Machine learning approaches revealed metabolic signatures of incident chronic kidney disease in persons with pre-and type 2 diabetes (2020) (0)
- Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels (2018) (0)
- Epigenome-wide association study reveals CpG sites associated with thyroid function and regulatory effects on KLF9. (2023) (0)
- Metabolite profiling reveals new insights into the regulation of serum urate in humans (2013) (0)
- Identification of functionally relevant genetic variants associated with multiple sclerosis using deep learning (2019) (0)
- Statistical Methods in Genetic and Molecular Epidemiology and Their Application in Studies with Metabolic Phenotypes (2012) (0)
- Genetic Determinants of IgG Synthesis in the Cerebrospinal Fluid of Patients with Multiple Sclerosis (S20.006) (2012) (0)
- ' s response to reviews Title : Multi-omic signature of body weight change : results from a population-based cohort study (2014) (0)
- Genome-wide physical activity interactions in adiposity A meta-analysis of 200,452 adults Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2017) (0)
- Correction: Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study (2017) (0)
- A catalog of genetic loci associated with kidney function from analyses of a million individuals (2019) (0)
- Omics: Potential Role in Early-Phase Drug Development (2015) (0)
- Title : Six new loci associated with body mass index highlight a neuronal influence on body weight regulation (0)
- Correction to: A network-based conditional genetic association analysis of the human metabolome (2019) (0)
- Higher Daily Air Temperature Is Associated with Shorter Leukocyte Telomere Length: KORA F3 and KORA F4 (2022) (0)
- Abstract 154: Sex-specific Genome Wide Association Study Of Early-onset Ischemic Stroke (2022) (0)
- Author Correction: Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease (2018) (0)
- Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies (2018) (0)
- Erratum (2014) (0)
- Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
- Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis (vol 50, pg 1072, 2018) (2018) (0)
- Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis (2018) (0)
- Novel Associations of TNFRSF 13 B , TNFSF 13 , and ANXA 3 with Serum levels of Non-albumin Protein and Immunoglobulin Isotypes in the Japanese Population ” (2011) (0)
- Supplementary Table S16 (2012) (0)
- Edinburgh Research Explorer Variation in the SERPINA6SERPINA1 locusalters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expressionin peripheral tissues, and risk of cardiovascular disease (2021) (0)
- Distribution of characteristics of the study population (n = 3,000) by PTSD status. (2013) (0)
- Report and Geographic Structure in Europe (0)
- Supplementary Material (nature09270-s1) (2012) (0)
- Publisher Correction: Identification of 371 genetic variants for age at first sex and birth linked to externalising behavior (2021) (0)
- Broadband IR-Fingerprinting of Human Blood as a Universal Tool for Diseases Diagnostics (2019) (0)
- Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation (2018) (0)
- Variants in eukaryotic translation initiation factor 4G1 in sporadic Parkinson’s disease (2012) (0)
- Genome-wide association study unravels genetic determinants of the atopic march (2016) (0)
- Chapter 17 Text mining in life sciences (2007) (0)
- DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures (2021) (0)
- New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (0)
- Common electrocardiogram measures are not associated with telomere length (2022) (0)
- Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019) (0)
- Review Process File (2012) (0)
- Intermediate clinical phenotype associations. (2015) (0)
- Author Correction: Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis (2022) (0)
- Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits (2020) (0)
- Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations (2018) (0)
- Aging- and stress-related epigenetic disinhibition of FKBP5 contributes to NF-κB-driven inflammation and cardiovascular risk (2017) (0)
- Long term conservation of human metabolic phenotypes and link to heritability (2014) (0)
- Genome Wide Meta-analysis Highlights the Role of Genetic Variation in RARRES 2 in the Regulation of Circulating Serum (2014) (0)
- Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway (2017) (0)
- Analysis of repeated leukocyte DNA methylation assessments reveals persistent epigenetic alterations after an incident myocardial infarction (2018) (0)
- Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (0)
- Mapping of the gene network that regulates glycan clock of ageing (2023) (0)
- Genome-wide meta-analysis of brachial circumference. (2011) (0)
- Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium (2014) (0)
- Abstract ED04-03: Interpretation of metabolomic data: Challenges and approaches (2013) (0)
- Age-related cataracts in a German population-based study (KORA S4) (2007) (0)
- Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls (2019) (0)
- Evaluating the Causal Relation of ApoA-IV with Disease-Related Traits - A Bidirectional Two-sample Mendelian Randomization Study (2017) (0)
- Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error (2018) (0)
- Iconographies supplémentaires de l'article : A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study (2012) (0)
- Restless Legs Syndrome-associated intronic common-variant in Meis 1 alters enhancer function in the developing telencephalon Supplemental Material (2014) (0)
- Erratum to: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis (Nature Genetics, (2018), 50, 8, (1072-1080), 10.1038/s41588-018-0157-1) (2018) (0)
- Effect of genome-wide simultaneous hypotheses tests on the discovery rate. (2011) (0)
- IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes (2018) (0)
- A Genomewide Association Study Of Plasma Total IGE In The Framingham Heart Study Identifies HLA-A As A Susceptibility Locus (2011) (0)
- Selected gene – polyunsaturated fatty acid interactions and risk of obesity (2010) (0)
- Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals (2018) (0)
- OP-EHEA170192_online 1823..1832 (2017) (0)
- The International Society of Biological and Environmental Repositories Presents Abstracts from Its Annual Meeting Breaking Down Walls: Unifying Biobanking Communities to Secure Our Sustainability April 5-8, 2016 Berlin, Germany. (2016) (0)
- Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (2022) (0)
- Epigenome-wide association reveals extensive perturbations in DNA methylation associated with adiposity and its adverse metabolic consequences. Authors (2015) (0)
- Detecting heritable phenotypes without a model using fast permutation testing for heritability and set-tests (2018) (0)
- Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles (2013) (0)
- Genome-wide characterization of a highly penetrant form of hyperlipoprotein(a)emia causatively associated with genetically elevated cardiovascular risk (2021) (0)
- Shortened leucocyte telomere length is associated with increased daily air temperature: KORA F3 and KORA F4 (2022) (0)
- Running title: Pfeiffer et al.; genome-wide DNA methylation and blood lipid levels (2015) (0)
- Genome-wide comparative analysis of atopic eczema and psoriasis gives insight into disease mechanisms (2014) (0)
- A genome-wide genetic pleiotropy approach identified shared loci between multiple system atrophy and inflammatory bowel disease (2019) (0)
- Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications (2023) (0)
- Correction: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses (2016) (0)
- MEIS1 and BTBD9-genetic association with RLS in end-stage renal disease (2020) (0)
- Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA Kettunen (0)
- On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies (2012) (0)
- alters enhancer function in the developing telencephalon Meis 1 Restless Legs Syndrome-associated intronic common variant in Material Supplemental (2014) (0)
- Psoriasis and cardiometabolic risk: independent association but distinct genetic architectures (2015) (0)
- pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms (2017) (0)
- Associations between lipoprotein subfractions and genome-wide DNA methylation in KORA F4 (2016) (0)
- Genome-wide association and HLA fine mapping studies identify risk loci and genetic 1 pathways of allergic rhinitis (2018) (0)
- Meta-Analysis of Maternal Prenatal Smoking GFI1-Locus and Cardio-Metabolic Phenotypes in Adults (2018) (0)
- Elucidating the genetic risk of obesity through the human blood plasma proteome (2020) (0)
- Mapping pQTLs of circulating inflammatory proteins identifies drivers of and novel therapeutic targets (2023) (0)
- Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects (2016) (0)
- Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels (2019) (0)
- Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error (2014) (0)
- Data integration and network analysis workflow for the blood metabolome-transcriptome interface (BMTI). (2015) (0)
- The effect of the LPA variant P.THR3888PRO on lipoprotein(a) and coronary artery disease is modified by the LPA KIV-2 splice site variant 4925g>A (2022) (0)
- Erratum (2012) (0)
- Omics: Potential Role in Early Phase Drug Development (2019) (0)
- Genome wide meta-analysis identifies novel regulators of circulating serum progranulin (2016) (0)
- OP-EHEA190237_online 2883..2898 (2019) (0)
- Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts (2015) (0)
- W1219 Genome-Wide Association Study for Ulcerative Colitis Demonstrates Novel Associations at Chromosome 22 and 7 (2010) (0)
- Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes (2017) (0)
- Genome-wide methylation data mirror ancestry information (2017) (0)
- The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus (2019) (0)
- Progressive Atherosclerosis and Incident Cardiovascular Disease Heme Oxygenase-1 Gene Promoter Microsatellite Polymorphism Is Associated With (2014) (0)
- DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function (2021) (0)
- University of Groningen Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci Tragante, (2014) (0)
- Comparative analysis of plasma metabolomics response to metabolic challenge tests in healthy subjects and influence of the FTO obesity risk allele (2013) (0)
- Rare variants in restless legs syndrome (2013) (0)
- Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations (2019) (0)
- Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps (2018) (0)
- Dense genotyping of six atopic dermatitis and 180 autoimmune risk loci in 2,425 atopic dermatitis patients (2013) (0)
- Systemic Biomarkers of Lung Function and FEV 1 Decline Across Multiple Cohorts (2020) (0)
- other inflammatory mediators circulating concentrations of monocyte chemoattractant protein-1 and Duffy antigen receptor for chemokines (Darc) polymorphism regulates (2014) (0)
- JMEDGENET87858 462..466 (0)
- Explorer Novel association to the proprotein convertase PCSK 7 gene locus revealed by analysing soluble transferrin receptor ( sTfR ) levels (2018) (0)
- Replication study of multiple sclerosis (MS) susceptibility alleles and correlation of DNA-variants with disease features in a cohort of Austrian MS patients (2012) (0)
- Systemic Biomarkers of Lung Function and FEV1 Decline Across Multiple Cohorts (2020) (0)
- Genome-wide association analysis identifies six new loci associated with forced vital capacity | NOVA. The University of Newcastle's Digital Repository (2014) (0)
- Metabolic Signatures Elucidate the Effect of Body Mass Index on Type 2 Diabetes (2023) (0)
- Association between the type and length of tumor necrosis factor ( TNF ) inhibitor therapy and myocardial infarction ( MI ) risk in psoriasis (2011) (0)
- University of Groningen Meta-Analysis of Genome-Wide Association Studies and Network Analysis-Based Integration with Gene Expression Data Identify New Suggestive Loci and Unravel a Wnt-Centric Network Associated with Dupuytren ' s Disease (2017) (0)
- Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis (2018) (0)
- Edinburgh Research Explorer Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2018) (0)
- Diminishing benefits of urban living for children and adolescents’ growth and development (2023) (0)
- Nature Genetics | Article (2015) (0)
- Long-term air pollution exposure is associated with molecular markers of accelerated molecular ageing (2016) (0)
- Marginal Regression Models with Varying Coefficients for Correlated Ordinal Data (1999) (0)
- Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
- Rare variants in LRRK1 and Parkinson's disease (2013) (0)
- Metabolomic Profiling of Age-Related Cataract (2012) (0)
- A polygenic and family risk score are both independently associated with risk of type 2 diabetes in a population-based study (2023) (0)
- P4769Using the plasma proteome to decipher metabolic syndrome pathophysiology and discover a diagnostic biomarker panel (2018) (0)
- Methylglyoxal – a central metabolic factor in restless legs syndrome? (2022) (0)
- Genome-wide DNA methylation analysis reveals several loci important for blood lipid levels (2015) (0)
- CAPON is a Novel QT-Interval Modifier Gene with Gender Dependent Effect Identified through Genomewide Association Analysis in Individuals from the General Population1 (2007) (0)
- Genome-Wide Analysis Identifies Regulators of Hematologic Parameters (2010) (0)
- Variation in the SERPINA6SERPINA1 locusalters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expressionin peripheral tissues, and risk of cardiovascular disease (2021) (0)
- Epigenome-wide association study of whole blood gene expression in Framingham Heart Study participants provides molecular insight into the potential role of CHRNA5 in cigarette smoking-related lung diseases (2021) (0)
- Advances in modeling of the bovine estrous cycle: Synchronization with PGF2 (2022) (0)
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What Schools Are Affiliated With Christian Gieger?
Christian Gieger is affiliated with the following schools:
