Christian Hertweck
Chemist
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Chemistry
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(Suggest an Edit or Addition)According to Wikipedia, Christian Hertweck is a German chemist, deputy director and head of the department of biomolecular chemistry at the Leibniz Institute for Natural Products Research and Infection Biology. Career Hertweck studied chemistry at the University of Bonn and did his doctorate under Wilhelm Boland at the Max Planck Institute for Chemical Ecology in 1996–1999. After a research stay with Heinz G. Floss and Bradley S. Moore at the University of Washington, Seattle, US, funded by a Feodor Lynen Research Fellowship for Postdoctoral Researchers , he started his independent research as head of a junior research group at the Hans Knöll Institute , which led to a habilitation in organic chemistry at the FSU Jena. Since 2006, he has been full professor at the Friedrich Schiller University Jena and head of the department of biomolecular chemistry at the Leibniz Institute for Natural Product Research and Infection Biology; in 2008 he became deputy director of the institute.
Christian Hertweck's Published Works
Published Works
- Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. (2013) (1360)
- The biosynthetic logic of polyketide diversity. (2009) (987)
- Minimum Information about a Biosynthetic Gene cluster. (2015) (600)
- Intimate bacterial–fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans (2009) (582)
- Chemical ecology of endophytic fungi: origins of secondary metabolites. (2012) (551)
- Pathogenic fungus harbours endosymbiotic bacteria for toxin production (2005) (548)
- Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans. (2007) (510)
- Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork. (2007) (432)
- Triggering cryptic natural product biosynthesis in microorganisms. (2009) (421)
- Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection (2008) (333)
- Symbiotic Streptomycetes provide antibiotic combination prophylaxis for wasp offspring. (2010) (322)
- The chemistry and biology of cytochalasans. (2010) (315)
- Bacteria-induced natural product formation in the fungus Aspergillus nidulans requires Saga/Ada-mediated histone acetylation (2011) (290)
- Enzymatic Carbon-Sulfur Bond Formation in Natural Product Biosynthesis. (2017) (276)
- Biosynthesis and attachment of novel bacterial polyketide synthase starter units. (2002) (261)
- Genomics-inspired discovery of natural products. (2011) (218)
- Endosymbiont-Dependent Host Reproduction Maintains Bacterial-Fungal Mutualism (2007) (209)
- A Gene Cluster Encoding Rhizoxin Biosynthesis in “Burkholderia rhizoxina”, the Bacterial Endosymbiont of the Fungus Rhizopus microsporus (2007) (201)
- Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi (2011) (184)
- Molecular basis of cytochalasan biosynthesis in fungi: gene cluster analysis and evidence for the involvement of a PKS-NRPS hybrid synthase by RNA silencing. (2007) (175)
- Closthioamide: an unprecedented polythioamide antibiotic from the strictly anaerobic bacterium Clostridium cellulolyticum. (2010) (166)
- Biosynthesis and function of gliotoxin in Aspergillus fumigatus (2011) (162)
- Xiamycin, a pentacyclic indolosesquiterpene with selective anti-HIV activity from a bacterial mangrove endophyte. (2010) (161)
- Burkholderia rhizoxinica sp. nov. and Burkholderia endofungorum sp. nov., bacterial endosymbionts of the plant-pathogenic fungus Rhizopus microsporus. (2007) (161)
- Molecular Diversity Sculpted by Fungal PKS–NRPS Hybrids (2013) (155)
- Iteration as programmed event during polyketide assembly; molecular analysis of the aureothin biosynthesis gene cluster. (2003) (155)
- Fungal phytotoxins as mediators of virulence. (2009) (149)
- Hidden biosynthetic treasures brought to light. (2009) (143)
- Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase. (2000) (141)
- Activation of a Silent Fungal Polyketide Biosynthesis Pathway through Regulatory Cross Talk with a Cryptic Nonribosomal Peptide Synthetase Gene Cluster (2010) (139)
- Advances in cloning, functional analysis and heterologous expression of fungal polyketide synthase genes. (2006) (139)
- Antimitotic rhizoxin derivatives from a cultured bacterial endosymbiont of the rice pathogenic fungus Rhizopus microsporus. (2006) (137)
- A family of multicyclic indolosesquiterpenes from a bacterial endophyte. (2011) (136)
- Microalgae in the postgenomic era: a blooming reservoir for new natural products. (2012) (134)
- Discovery of aspoquinolones A-D, prenylated quinoline-2-one alkaloids from Aspergillus nidulans, motivated by genome mining. (2006) (131)
- Rhizonin, the First Mycotoxin Isolated from the Zygomycota, Is Not a Fungal Metabolite but Is Produced by Bacterial Endosymbionts (2006) (129)
- Ribosomal synthesis of tricyclic depsipeptides in bloom-forming cyanobacteria. (2008) (129)
- Symbiont-Derived Antimicrobials Contribute to the Control of the Lepidopteran Gut Microbiota. (2017) (123)
- Analysis of the Aspergillus fumigatus Proteome Reveals Metabolic Changes and the Activation of the Pseurotin A Biosynthesis Gene Cluster in Response to Hypoxia (2011) (123)
- Transannular disulfide formation in gliotoxin biosynthesis and its role in self-resistance of the human pathogen Aspergillus fumigatus. (2010) (121)
- The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus (2011) (121)
- Molecular Basis for Mycophenolic Acid Biosynthesis in Penicillium brevicompactum (2011) (116)
- Optimisation of a 2-D gel electrophoresis protocol for the human-pathogenic fungus Aspergillus fumigatus (2006) (115)
- Molecular bacteria-fungi interactions: effects on environment, food, and medicine. (2013) (115)
- Phenalenone-type phytoalexins mediate resistance of banana plants (Musa spp.) to the burrowing nematode Radopholus similis (2013) (115)
- Microcyclamide Biosynthesis in Two Strains of Microcystis aeruginosa: from Structure to Genes and Vice Versa (2008) (113)
- Antibiotics from neglected bacterial sources. (2014) (112)
- Bacterium Induces Cryptic Meroterpenoid Pathway in the Pathogenic Fungus Aspergillus fumigatus (2013) (111)
- Activation of fungal silent gene clusters: a new avenue to drug discovery. (2008) (110)
- Genomics-driven discovery of burkholderic acid, a noncanonical, cryptic polyketide from human pathogenic Burkholderia species. (2012) (106)
- Endofungal bacterium controls its host by an hrp type III secretion system (2010) (105)
- A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis. (2011) (103)
- Plant-like biosynthetic pathways in bacteria: from benzoic acid to chalcone. (2002) (103)
- Biosynthesis and structure of aeruginoside 126A and 126B, cyanobacterial peptide glycosides bearing a 2-carboxy-6-hydroxyoctahydroindole moiety. (2007) (102)
- Biosynthetic origin of the rare nitroaryl moiety of the polyketide antibiotic aureothin: involvement of an unprecedented N-oxygenase. (2004) (100)
- Vinylogous chain branching catalysed by a dedicated polyketide synthase module (2013) (99)
- Antibiotic-producing symbionts dynamically transition between plant pathogenicity and insect-defensive mutualism (2017) (98)
- Botryorhodines A-D, antifungal and cytotoxic depsidones from Botryosphaeria rhodina, an endophyte of the medicinal plant Bidens pilosa. (2010) (97)
- Evolution of an endofungal Lifestyle: Deductions from the Burkholderia rhizoxinica Genome (2011) (96)
- Keratin degradation by dermatophytes relies on cysteine dioxygenase and a sulfite efflux pump. (2013) (94)
- Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus terreus. (2011) (91)
- Active invasion of bacteria into living fungal cells (2014) (91)
- Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria (2014) (91)
- Plasticity and Evolution of Aeruginosin Biosynthesis in Cyanobacteria (2009) (90)
- Terrein biosynthesis in Aspergillus terreus and its impact on phytotoxicity. (2014) (88)
- Terpenoid biosynthesis off the beaten track: unconventional cyclases and their impact on biomimetic synthesis. (2015) (88)
- Bacterial synthesis of diverse indole terpene alkaloids by an unparalleled cyclization sequence. (2012) (86)
- Biosynthesis of Nitro Compounds (2007) (85)
- Functionally distinct modules operate two consecutive alpha,beta-->beta,gamma double-bond shifts in the rhizoxin polyketide assembly line. (2010) (85)
- Complete Genome Sequence of Burkholderia rhizoxinica, an Endosymbiont of Rhizopus microsporus (2010) (84)
- Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin (2010) (84)
- Exploiting the Natural Diversity of Microviridin Gene Clusters for Discovery of Novel Tricyclic Depsipeptides (2010) (82)
- Endofungal bacteria as producers of mycotoxins. (2009) (81)
- A genomic approach to the cryptic secondary metabolome of the anaerobic world. (2013) (80)
- Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide. (2005) (79)
- Structure and alignment of the membrane-associated peptaibols ampullosporin A and alamethicin by oriented 15N and 31P solid-state NMR spectroscopy. (2009) (79)
- Triggering Cryptic Natural Product Biosynthesis in Microorganisms (2009) (74)
- Divergolides A-D from a mangrove endophyte reveal an unparalleled plasticity in ansa-macrolide biosynthesis. (2011) (73)
- Opposed effects of enzymatic gliotoxin N- and S-methylations. (2014) (73)
- Decoding and reprogramming complex polyketide assembly lines: prospects for synthetic biology. (2015) (72)
- Functionally Distinct Modules Operate Two Consecutive α,β→β,γ Double‐Bond Shifts in the Rhizoxin Polyketide Assembly Line (2010) (72)
- Global Distribution and Evolution of a Toxinogenic Burkholderia-Rhizopus Symbiosis (2009) (70)
- Evolution of host resistance in a toxin-producing bacterial–fungal alliance (2008) (70)
- Biosynthesis of the halogenated mycotoxin aspirochlorine in koji mold involves a cryptic amino acid conversion. (2014) (68)
- Biosynthesis of the respiratory toxin bongkrekic acid in the pathogenic bacterium Burkholderia gladioli. (2012) (68)
- An antifungal polyketide associated with horizontally acquired genes supports symbiont-mediated defense in Lagria villosa beetles (2018) (68)
- Formation of the aureothin tetrahydrofuran ring by a bifunctional cytochrome p450 monooxygenase. (2004) (68)
- Symbiotic cooperation in the biosynthesis of a phytotoxin. (2012) (67)
- Induced biosynthesis of cryptic polyketide metabolites in a Burkholderia thailandensis quorum sensing mutant. (2010) (66)
- Mining and unearthing hidden biosynthetic potential (2021) (66)
- Bioinspired total synthesis of sespenine. (2014) (65)
- Polyketide-chain branching by an enzymatic Michael addition. (2009) (63)
- Sequential enzymatic oxidation of aminoarenes to nitroarenes via hydroxylamines. (2005) (62)
- A Non-canonical Melanin Biosynthesis Pathway Protects Aspergillus terreus Conidia from Environmental Stress. (2016) (62)
- A gene cluster encoding resistomycin biosynthesis in Streptomyces resistomycificus; exploring polyketide cyclization beyond linear and angucyclic patterns. (2004) (60)
- Regiodivergent N-C and N-N aryl coupling reactions of indoloterpenes and cycloether formation mediated by a single bacterial flavoenzyme. (2013) (59)
- A cryptic PKS-NRPS gene locus in the plant commensal Pseudomonas fluorescens Pf-5 codes for the biosynthesis of an antimitotic rhizoxin complex. (2007) (59)
- Chemical warfare between leafcutter ant symbionts and a co-evolved pathogen (2018) (58)
- Tuf of Streptococcus pneumoniae is a surface displayed human complement regulator binding protein. (2014) (58)
- Gramibactin is a bacterial siderophore with a diazeniumdiolate ligand system (2018) (58)
- The molecular basis of conjugated polyyne biosynthesis in phytopathogenic bacteria. (2014) (57)
- Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids. (2007) (56)
- Kandenols A-E, eudesmenes from an endophytic Streptomyces sp. of the mangrove tree Kandelia candel. (2012) (55)
- Epidithiol formation by an unprecedented twin carbon-sulfur lyase in the gliotoxin pathway. (2012) (55)
- Aspernidine A and B, prenylated isoindolinone alkaloids from the model fungus Aspergillus nidulans (2010) (55)
- Epidithiodiketopiperazine biosynthesis: a four-enzyme cascade converts glutathione conjugates into transannular disulfide bridges. (2013) (54)
- Functional Analysis of the Aureothin Iterative Type I Polyketide Synthase (2005) (53)
- Biosynthesis of antifungal and antibacterial polyketides by Burkholderia gladioli in coculture with Rhizopus microsporus (2014) (53)
- Context-dependent behavior of the enterocin iterative polyketide synthase; a new model for ketoreduction. (2004) (53)
- A branched extender unit shared between two orthogonal polyketide pathways in an endophyte. (2011) (53)
- Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals (2015) (52)
- ScbA from Streptomyces coelicolor A3(2) has homology to fatty acid synthases and is able to synthesize gamma-butyrolactones. (2007) (52)
- A Mechanism of Benzoic Acid Biosynthesis in Plants and Bacteria that Mirrors Fatty Acid β‐Oxidation (2001) (52)
- A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis. (2012) (52)
- Biomimetic Thioesters as Probes for Enzymatic Assembly Lines: Synthesis, Applications, and Challenges. (2016) (52)
- Vegetation-derived abscisic acid and four terpenes enforce dormancy in seeds of the post-fire annual, Nicotiana attenuata (2002) (52)
- Leader peptide and a membrane protein scaffold guide the biosynthesis of the tricyclic peptide microviridin. (2011) (52)
- Biosynthesis of polyunsaturated fatty acids by polyketide synthases. (2002) (52)
- Mutasynthesis of aureonitrile: an aureothin derivative with significantly improved cytostatic effect. (2005) (51)
- Discovery of clostrubin, an exceptional polyphenolic polyketide antibiotic from a strictly anaerobic bacterium. (2014) (51)
- Polyketide proofreading by an acyltransferase-like enzyme. (2012) (51)
- Structural fine-tuning of a multifunctional cytochrome P450 monooxygenase. (2011) (51)
- Imaging mass spectrometry and genome mining reveal highly antifungal virulence factor of mushroom soft rot pathogen. (2012) (51)
- A Plant-like Biosynthesis of Benzoyl-CoA in the Marine Bacterium ‘Streptomyces maritimus’ (2000) (51)
- Cervimycin A-D: a polyketide glycoside complex from a cave bacterium can defeat vancomycin resistance. (2005) (49)
- Epicoccarines A, B and epipyridone: tetramic acids and pyridone alkaloids from an Epicoccum sp. associated with the tree fungus Pholiota squarrosa. (2007) (49)
- Structure and action of the N-oxygenase AurF from Streptomyces thioluteus. (2007) (49)
- Antagonistic bacteria disrupt calcium homeostasis and immobilize algal cells (2017) (49)
- Detection of antibiotics synthetized in microfluidic picolitre-droplets by various actinobacteria (2018) (48)
- Biosynthesis of pentangular polyphenols: deductions from the benastatin and griseorhodin pathways. (2007) (47)
- The Fungal Quorum-Sensing Molecule Farnesol Activates Innate Immune Cells but Suppresses Cellular Adaptive Immunity (2015) (47)
- Quercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill). (2007) (46)
- Mutasynthesis of enterocin and wailupemycin analogues. (2003) (46)
- On-line enzymatic tailoring of polyketides and peptides in thiotemplate systems. (2016) (46)
- Antimicrobial discovery inspired by ecological interactions. (2017) (45)
- Plant pathogenic anaerobic bacteria use aromatic polyketides to access aerobic territory (2015) (45)
- Nitro versus hydroxamate in siderophores of pathogenic bacteria: effect of missing hydroxylamine protection in malleobactin biosynthesis. (2013) (45)
- Impact of Endofungal Bacteria on Infection Biology, Food Safety, and Drug Development (2011) (44)
- Photochemical origin of the immunosuppressive SNF4435C/D and formation of orinocin through "polyene splicing". (2006) (44)
- Sequential asymmetric polyketide heterocyclization catalyzed by a single cytochrome P450 monooxygenase (AurH). (2008) (44)
- Distinct Amino Acids of Histone H3 Control Secondary Metabolism in Aspergillus nidulans (2013) (44)
- Unexpected Bacterial Origin of the Antibiotic Icosalide: Two-Tailed Depsipeptide Assembly in Multifarious Burkholderia Symbionts. (2018) (43)
- Nostopeptolide plays a governing role during cellular differentiation of the symbiotic cyanobacterium Nostoc punctiforme (2015) (43)
- Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues. (2010) (42)
- Artificial Reconstruction of Two Cryptic Angucycline Antibiotic Biosynthetic Pathways (2007) (41)
- Antiterminator-mediated unveiling of cryptic polythioamides in an anaerobic bacterium. (2012) (41)
- Anaerobic bacteria as producers of antibiotics (2012) (40)
- An unusual galactofuranose lipopolysaccharide that ensures the intracellular survival of toxin-producing bacteria in their fungal host. (2010) (40)
- Pseudoxylallemycins A-F, Cyclic Tetrapeptides with Rare Allenyl Modifications Isolated from Pseudoxylaria sp. X802: A Competitor of Fungus-Growing Termite Cultivars. (2016) (40)
- Mediators of mutualistic microbe-microbe interactions. (2018) (40)
- Cytotoxic pheofungins from an engineered fungus impaired in posttranslational protein modification. (2011) (40)
- Harnessing the evolvability of tricyclic microviridins to dissect protease-inhibitor interactions. (2014) (39)
- Synthetic remodeling of the chartreusin pathway to tune antiproliferative and antibacterial activities. (2013) (39)
- Orchestration of discoid polyketide cyclization in the resistomycin pathway. (2008) (39)
- Three Redundant Synthetases Secure Redox-Active Pigment Production in the Basidiomycete Paxillus involutus. (2015) (39)
- Chromatin mapping identifies BasR, a key regulator of bacteria-triggered production of fungal secondary metabolites (2018) (38)
- Factors Supporting Cysteine Tolerance and Sulfite Production in Candida albicans (2013) (38)
- Anti-inflammatory and anti-hyaluronate lyase activities of lanostanoids from Piptoporus betulinus. (2004) (38)
- Regio- and chemoselective enzymatic N-oxygenation in vivo, in vitro, and in flow. (2006) (38)
- Biosynthesis of the antimetabolite 6-thioguanine in Erwinia amylovora plays a key role in fire blight pathogenesis. (2013) (37)
- Flavoenzyme-catalyzed formation of disulfide bonds in natural products. (2014) (37)
- Metal-Free Synthesis of Pharmaceutically Important Biaryls by Photosplicing. (2018) (37)
- Horizontal Gene Transfer to a Defensive Symbiont with a Reduced Genome in a Multipartite Beetle Microbiome (2020) (37)
- Two Induced Fungal Polyketide Pathways Converge into Antiproliferative Spiroanthrones (2011) (37)
- Evolutionary Imprint of Catalytic Domains in Fungal PKS–NRPS Hybrids (2012) (36)
- Rational design of modular polyketide synthases: morphing the aureothin pathway into a luteoreticulin assembly line. (2014) (36)
- Genomics‐Driven Discovery of NO‐Donating Diazeniumdiolate Siderophores in Diverse Plant‐Associated Bacteria (2019) (35)
- Targeted induction of a silent fungal gene cluster encoding the bacteria-specific germination inhibitor fumigermin (2020) (35)
- Bacterial Synthesis of Unusual Sulfonamide and Sulfone Antibiotics by Flavoenzyme-Mediated Sulfur Dioxide Capture. (2015) (34)
- Differential expression of silent polyketide biosynthesis gene clusters in chemostat cultures of Aspergillus nidulans. (2012) (34)
- Cytotoxic alkaloids from Fusarium incarnatum associated with the mangrove tree Aegiceras corniculatum. (2012) (34)
- Inotilone and related phenylpropanoid polyketides from Inonotus sp. and their identification as potent COX and XO inhibitors. (2006) (33)
- Cryptic Polyketide Synthase Genes in Non-Pathogenic Clostridium SPP (2012) (32)
- Multifactorial control of iteration events in a modular polyketide assembly line. (2013) (32)
- A functional link between hyphal maintenance and quorum sensing in Candida albicans (2017) (32)
- Evolution of metabolic diversity in polyketide-derived pyrones: using the non-colinear aureothin assembly line as a model system. (2009) (32)
- Epicoccamides B-D, glycosylated tetramic acid derivatives from an Epicoccum sp. associated with the tree fungus Pholiota squarrosa. (2007) (31)
- Toxin production by bacterial endosymbionts of a Rhizopus microsporus strain used for tempe/sufu processing. (2010) (31)
- Convergent asymmetric synthesis of (+)-aureothin employing an oxygenase-mediated resolution step. (2012) (31)
- Natural 1,3-Dipolar Cycloadditions. (2015) (31)
- Daldionin, an Unprecedented Binaphthyl Derivative, and Diverse Polyketide Congeners from a Fungal Orchid Endophyte. (2016) (31)
- Dissection of the Late Steps in Aureothin Biosynthesis (2006) (31)
- Highly parallelized droplet cultivation and prioritization of antibiotic producers from natural microbial communities (2021) (31)
- Mode of action of closthioamide: the first member of the polythioamide class of bacterial DNA gyrase inhibitors. (2015) (30)
- The boat-shaped polyketide resistoflavin results from re-facial central hydroxylation of the discoid metabolite resistomycin. (2006) (30)
- A Pair of Bacterial Siderophores Releases and Traps an Intercellular Signal Molecule: An Unusual Case of Natural Nitrone Bioconjugation. (2018) (30)
- Total Synthesis of the Antitumor Natural Product Polycarcin V and Evaluation of Its DNA Binding Profile (2014) (29)
- A binuclear manganese cluster that catalyzes radical-mediated N-oxygenation. (2007) (29)
- Transcriptome analysis of cyclic AMP‐dependent protein kinase A–regulated genes reveals the production of the novel natural compound fumipyrrole by Aspergillus fumigatus (2015) (29)
- Simultaneous Production of Psilocybin and a Cocktail of β‐Carboline Monoamine Oxidase Inhibitors in “Magic” Mushrooms (2019) (29)
- Plasticity in gilvocarcin-type C-glycoside pathways: discovery and antitumoral evaluation of polycarcin V from Streptomyces polyformus. (2008) (29)
- Elaiomycins D-F, antimicrobial and cytotoxic azoxides from Streptomyces sp. strain HKI0708. (2012) (29)
- Natural Products as Source of Therapeutics against Parasitic Diseases. (2015) (28)
- Functional Analysis of Environmental DNA-Derived Microviridins Provides New Insights into the Diversity of the Tricyclic Peptide Family (2013) (28)
- Squarrosidine and Pinillidine: 3,3′-Fused Bis(styrylpyrones) from Pholiota squarrosa and Phellinus pini (2007) (28)
- Assembly and absolute configuration of short-lived polyketides from Burkholderia thailandensis. (2012) (28)
- Formation of a dinuclear copper(I) complex from the Clostridium-derived antibiotic closthioamide. (2013) (27)
- Enzymatic polyketide chain branching to give substituted lactone, lactam, and glutarimide heterocycles. (2014) (27)
- Regioselective Dichlorination of a Non-Activated Aliphatic Carbon Atom and Phenolic Bismethylation by a Multifunctional Fungal Flavoenzyme. (2016) (27)
- Emulating evolutionary processes to morph aureothin-type modular polyketide synthases and associated oxygenases (2019) (26)
- Benzopyrenomycin, a cytotoxic bacterial polyketide metabolite with a benzo[a]pyrene-type carbocyclic ring system. (2008) (26)
- Lack of evidence of endosymbiotic toxin‐producing bacteria in clinical Rhizopus isolates (2008) (26)
- Highly Efficient Total Synthesis of the Clostridium-Derived anti-MRSA Antibiotic Closthioamide (2011) (26)
- Polyketide synthase chimeras reveal key role of ketosynthase domain in chain branching. (2015) (26)
- Epicoccalone, a Coumarin-Type Chymotrypsin Inhibitor, and Isobenzofuran Congeners from an Epicoccum sp. Associated with a Tree Fungus (2008) (26)
- Chemical Mediators at the Bacterial-Fungal Interface. (2020) (26)
- Plasticity of the malleobactin pathway and its impact on siderophore action in human pathogenic bacteria. (2015) (26)
- Pitucamycin: structural merger of a phenoxazinone with an epoxyquinone antibiotic. (2010) (26)
- Induced Chemical Defense of a Mushroom by a Double-Bond-Shifting Polyene Synthase. (2017) (25)
- Freedom and constraint in engineered noncolinear polyketide assembly lines. (2015) (25)
- Antifungal potential of secondary metabolites involved in the interaction between citrus pathogens (2019) (25)
- Biosynthetic Code for Divergolide Assembly in a Bacterial Mangrove Endophyte (2014) (25)
- Biosynthesis of cervimycin C, an aromatic polyketide antibiotic bearing an unusual dimethylmalonyl moiety. (2004) (24)
- Biosynthesis and Mass Spectrometric Imaging of Tolaasin, the Virulence Factor of Brown Blotch Mushroom Disease (2013) (24)
- A Highly Conserved Basidiomycete Peptide Synthetase Produces a Trimeric Hydroxamate Siderophore (2017) (24)
- A Fivefold Parallelized Biosynthetic Process Secures Chlorination of Armillaria mellea (Honey Mushroom) Toxins (2015) (24)
- Two Types of Threonine-Tagged Lipopeptides Synergize in Host Colonization by Pathogenic Burkholderia Species. (2018) (23)
- Biosynthesis of the mitochondrial adenine nucleotide translocase (ATPase) inhibitor bongkrekic acid in Burkholderia gladioli. (2010) (22)
- Cyclopropanol Warhead in Malleicyprol Confers Virulence of Human‐ and Animal‐Pathogenic Burkholderia Species (2019) (22)
- Insect‐Associated Bacteria Assemble the Antifungal Butenolide Gladiofungin by Non‐Canonical Polyketide Chain Termination (2020) (22)
- Geminal bismethylation prevents polyketide oxidation and dimerization in the benastatin pathway. (2007) (22)
- High-Density Cultivation of Terrestrial Nostoc Strains Leads to Reprogramming of Secondary Metabolome (2017) (22)
- Evolution of siderophore pathways in human pathogenic bacteria. (2014) (22)
- Genome Editing Reveals Novel Thiotemplated Assembly of Polythioamide Antibiotics in Anaerobic Bacteria. (2018) (22)
- Geminal tandem C-methylation in the discoid resistomycin pathway. (2007) (21)
- Bacaryolanes A-C, Rare Bacterial Caryolanes from a Mangrove Endophyte. (2015) (21)
- Enzymatic Thioamide Formation in a Bacterial Antimetabolite Pathway. (2018) (21)
- Ketosynthase III as a gateway to engineering the biosynthesis of antitumoral benastatin derivatives. (2009) (20)
- Farinamycin, a quinazoline from Streptomyces griseus. (2011) (20)
- Lichen-like association of Chlamydomonas reinhardtii and Aspergillus nidulans protects algal cells from bacteria (2020) (20)
- Cryptic indole hydroxylation by a non-canonical terpenoid cyclase parallels bacterial xenobiotic detoxification (2017) (20)
- Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ. (2017) (19)
- Cervimycin C resistance in Bacillus subtilis is due to a promoter up-mutation and increased mRNA stability of the constitutive ABC-transporter gene bmrA. (2010) (19)
- Injury‐Triggered Blueing Reactions of Psilocybe “Magic” Mushrooms (2019) (19)
- Biosynthesis and charging of pyrrolysine, the 22nd genetically encoded amino acid. (2011) (19)
- Stereochemical Specificity of Lamoxirene, the Sperm-Releasing Pheromone in Kelp (Laminariales, Phaeophyceae) (2001) (19)
- Hydrazidomycins, cytotoxic alkylhydrazides from Streptomycesatratus. (2011) (19)
- Food preparation with mucoralean fungi: A potential biosafety issue? (2016) (18)
- Rational design of an apoptosis-inducing photoreactive DNA intercalator. (2013) (18)
- Genomics-guided discovery of endophenazines from Kitasatospora sp. HKI 714. (2014) (18)
- Bezerramycins A-C, Antiproliferative Phenoxazinones from Streptomyces griseus Featuring Carboxy, Carboxamide or Nitrile Substituents (2010) (18)
- Isoflavones with unusually modified B-rings and their evaluation as antiproliferative agents. (2009) (18)
- Interchenar retrotransfer of aureothin intermediates in an iterative polyketide synthase module. (2012) (17)
- Biosynthesis of Fungal Polyketides (2009) (17)
- Characterization of Burkholderia rhizoxinica and B. endofungorum Isolated from Clinical Specimens (2011) (17)
- Bacterial endosymbionts protect beneficial soil fungus from nematode attack (2021) (17)
- Hygrobafilomycin, a cytotoxic and antifungal macrolide bearing a unique monoalkylmaleic anhydride moiety, from Streptomyces varsoviensis (2010) (17)
- A concise total synthesis of sespenine, a structurally unusual indole terpenoid from Streptomyces (2016) (17)
- Assessing Oxazole Bioisosteres as Mutasynthons on the Rhizoxin Assembly Line (2011) (17)
- A polyketide interferes with cellular differentiation in the symbiotic cyanobacterium Nostoc punctiforme. (2011) (17)
- Genomics‐Driven Discovery of a Symbiont‐Specific Cyclopeptide from Bacteria Residing in the Rice Seedling Blight Fungus (2018) (16)
- Asymmetric α-Chloroallylboration of Amino Aldehydes: A Novel and Highly Versatile Route to d- and l-erythro-Sphingoid Bases (1999) (16)
- Copper(II) Triflate in Organic Synthesis (2000) (16)
- Discovery of an Extended Austinoid Biosynthetic Pathway in Aspergillus calidoustus. (2017) (16)
- Mapping of the modular closthioamide architecture reveals crucial motifs of polythioamide antibiotics. (2014) (15)
- Divergolide congeners illuminate alternative reaction channels for ansamycin diversification. (2015) (15)
- Structure, Genetics and Function of an Exopolysaccharide Produced by a Bacterium Living within Fungal Hyphae (2015) (15)
- Comparison of Proteomic Responses as Global Approach to Antibiotic Mechanism of Action Elucidation (2020) (15)
- Cover Picture: A Gene Cluster Encoding Rhizoxin Biosynthesis in “Burkholderia rhizoxina”, the Bacterial Endosymbiont of the Fungus Rhizopus microsporus (ChemBioChem 1/2007) (2007) (15)
- Control of Plant Defense Mechanisms and Fire Blight Pathogenesis through the Regulation of 6‐Thioguanine Biosynthesis in Erwinia amylovora (2014) (15)
- Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F) (2013) (15)
- esized and post-translationally modi fi ed peptide natural products : overview and recommendations for a universal nomenclature (2012) (15)
- A giant type I polyketide synthase participates in zygospore maturation in Chlamydomonas reinhardtii (2018) (14)
- Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis. (2021) (14)
- Reconstitution of polythioamide antibiotic backbone formation reveals unusual thiotemplated assembly strategy (2020) (14)
- Pyran Formation by an Atypical CYP‐Mediated Four‐Electron Oxygenation–Cyclization Cascade in an Engineered Aureothin Pathway (2012) (14)
- Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase. (2019) (14)
- Metabolic pathway rerouting in Paraburkholderia rhizoxinica evolved long-overlooked derivatives of coenzyme F420. (2019) (14)
- Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function (2022) (13)
- head to head polyketide fusion by CorB † (2015) (13)
- Genome Mining Reveals Endopyrroles from a Nonribosomal Peptide Assembly Line Triggered in Fungal-Bacterial Symbiosis. (2019) (13)
- Unique Biosynthetic Pathway in Bloom-Forming Cyanobacterial Genus Microcystis Jointly Assembles Cytotoxic Aeruginoguanidines and Microguanidines. (2018) (13)
- Tandem reduction-chloroallylboration of esters: asymmetric synthesis of lamoxirene, the spermatozoid releasing and attracting pheromone of the laminariales (Phaeophyceae). (2000) (13)
- Structural characterization of two lipopolysaccharide O-antigens produced by the endofungal bacterium Burkholderia sp. HKI-402 (B4). (2012) (12)
- Nebularic Acids and Nebularilactones, Novel Drimane Sesquiterpenoids from the Fungus Lepista nebularis (2006) (12)
- Sulfonium Acids Loaded onto an Unusual Thiotemplate Assembly Line Construct the Cyclopropanol Warhead of a Burkholderia Virulence Factor (2020) (12)
- Loss of Single‐Domain Function in a Modular Assembly Line Alters the Size and Shape of a Complex Polyketide (2019) (12)
- Reconstitution of Iterative Thioamidation in Closthioamide Biosynthesis Reveals Tailoring Strategy for Nonribosomal Peptide Backbones (2019) (12)
- Genomics-driven discovery of a linear lipopeptide promoting host colonization by endofungal bacteria. (2018) (12)
- Genome Sequence of Mushroom Soft-Rot Pathogen Janthinobacterium agaricidamnosum (2015) (12)
- Mining Symbionts of a Spider‐Transmitted Fungus Illuminates Uncharted Biosynthetic Pathways to Cytotoxic Benzolactones (2020) (12)
- The Multiplasmid Approach: A New Perspective for Combinatorial Biosynthesis (2000) (12)
- Disruption of Membrane Integrity by the Bacterium-Derived Antifungal Jagaricin (2019) (11)
- Exploring the chemical space of microbial natural products. (2009) (11)
- Molecular Diversity Sculpted by Fungal PKS—NRPS Hybrids (2013) (11)
- Genome Mining and Heterologous Expression Reveal Two Distinct Families of Lasso Peptides Highly Conserved in Endofungal Bacteria. (2019) (11)
- Biosynthesis of Diverse Antimicrobial and Antiproliferative Acyloins in Anaerobic Bacteria. (2019) (11)
- Helper bacteria halt and disarm mushroom pathogens by linearizing structurally diverse cyclolipopeptides (2020) (11)
- Melleolides impact fungal translation via elongation factor 2. (2019) (11)
- Antiproliferative Effects of Ester‐ and Amide‐Functionalized Rhizoxin Derivatives (2011) (10)
- Clostrindolin is an antimycobacterial pyrone alkaloid from Clostridium beijerinckii. (2019) (10)
- A Ribonucleotide Reductase‐Like Electron Transfer System in the Nitroaryl‐Forming N‐Oxygenase AurF (2011) (10)
- Twofold polyketide branching by a stereoselective enzymatic Michael addition. (2015) (10)
- Fungal Genome Mining and Activation of Silent Gene Clusters (2009) (10)
- Matrix-free single-cell LDI-MS investigations of the diatoms Coscinodiscus granii and Thalassiosira pseudonana. (2014) (10)
- Synthesis and biological evaluation of hydrazidomycin analogues. (2013) (10)
- Semisynthetic preparation of leucomycin derivatives: Introduction of aromatic side chains by reductive amination (2005) (10)
- Biosynthesis of Archetypal Plant Self‐Defensive Oxylipins by an Endophytic Fungus Residing in Mangrove Embryos (2012) (10)
- Biosynthesis of Sinapigladioside, an Antifungal Isothiocyanate from Burkholderia Symbionts (2021) (9)
- Anti-bacterial activities and phytochemical screening of extracts of different parts of Thalictrum rhynchocarpum. (2013) (9)
- Mapping Natural Dyes in Archeological Textiles by Imaging Mass Spectrometry (2019) (9)
- A widespread bacterial phenazine forms S-conjugates with biogenic thiols and crosslinks proteins† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc00503a (2016) (9)
- Dandamycin and chandrananimycin E, benzoxazines from Streptomyces griseus (2015) (9)
- Draft Genome Sequences of Symbiotic and Nonsymbiotic Rhizopus microsporus Strains CBS 344.29 and ATCC 62417 (2015) (9)
- Cervimycin A—D: A Polyketide Glycoside Complex from a Cave Bacterium Can Defeat Vancomycin Resistance. (2006) (9)
- Ribosome-independent peptide biosynthesis: the challenge of a unifying nomenclature. (2021) (8)
- Enzymatic Amide Tailoring Promotes Retro-Aldol Amino Acid Conversion To Form the Antifungal Agent Aspirochlorine. (2018) (8)
- Concise Total Synthesis of Hydrazidomycin A, a Rare Hydrazide Metabolite of Streptomyces atratus (2013) (8)
- Iron Coordination Properties of Gramibactin as Model for the New Class of Diazeniumdiolate Based Siderophores (2020) (8)
- AoiQ Catalyzes Geminal Dichlorination of 1,3-Diketone Natural Products. (2021) (8)
- Biosynthesis of Polyunsaturated Fatty Acids by Polyketide Synthases (2002) (8)
- Metabolic pathway rerouting in Paraburkholderia rhizoxinica evolved long-overlooked derivatives of coenzyme F420 (2019) (8)
- The bacterium Pseudomonas protegens antagonizes the microalga Chlamydomonas reinhardtii using a blend of toxins. (2021) (7)
- Metal‐Free Aryl Cross‐Coupling Directed by Traceless Linkers† (2019) (7)
- (6r,7r)4,5,6,7-H-2(4) -palmitoate and (8S,9R)-[8,9-H-2(2)]-L-erythro-sphinganine: Probes for the analysis of the stereochemical course of Delta(6)-desaturases from plants and insects (1999) (7)
- Structural and biochemical basis for the firm chemo- and regioselectivity of the nitro-forming N-oxygenase AurF. (2010) (7)
- Metal-Free Synthesis of Pharmaceutically Important Biaryls by Photosplicing (2018) (7)
- A highly efficient and versatile synthesis of D- and L-erythro-sphinganine (2001) (7)
- Reductive chloro- and thioallylations: Stereoselective two-step transformations of esters and lactones into functionalized cis- and trans-vinyloxiranes (1998) (7)
- Reconstitution of Enzymatic Carbon-Sulfur Bond Formation Reveals Detoxification-Like Strategy in Fungal Toxin Biosynthesis. (2018) (7)
- A polyyne toxin produced by an antagonistic bacterium blinds and lyses a Chlamydomonad alga (2021) (7)
- Injury‐Triggered Blueing Reactions of Psilocybe “Magic” Mushrooms (2019) (6)
- Divergolides A—D from a Mangrove Endophyte Reveal an Unparalleled Plasticity in ansa-Macrolide Biosynthesis. (2011) (6)
- Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead (2022) (6)
- ChemInform Abstract: Aspernidine A and B, Prenylated Isoindolinone Alkaloids from the Model Fungus Aspergillus nidulans. (2010) (6)
- A Pair of Bacterial Siderophores Releases and Traps an Intercellular Signal Molecule: An Unusual Case of Natural Nitrone Bioconjugation (2018) (6)
- Efficient synthesis of 9- and 13-oxo leucomycin derivatives using hypervalent iodine reagents in solution and on solid support. (2005) (6)
- HORSE LIVER ALCOHOL DEHYDROGENASE (HLADH); BIOCATALYTIC REDOX-TRANSFORMATIONS IN ORGANIC SYNTHESIS (1998) (6)
- Xiamycin (I), a Pentacyclic Indolosesquiterpene with Selective anti‐HIV Activity from a Bacterial Mangrove Endophyte. (2011) (6)
- Discovery of the Pseudomonas Polyyne Protegencin by a Phylogeny-Guided Study of Polyyne Biosynthetic Gene Cluster Diversity (2021) (6)
- Aldolase Antibody 38C2: A Biocatalyst Expanding the Scope of Enzymatic Transformations (2000) (6)
- Highly efficient synthesis of (±)-lamoxirene, the gamete-releasing and gamete-attracting pheromone of the Laminariales (Phaeophyta) (1997) (6)
- Highly parallelized microfluidic droplet cultivation and prioritization on antibiotic producers from complex natural microbial communities (2019) (6)
- On-Line Polyketide Cyclization into Diverse Medium-Sized Lactones by a Specialized Ketosynthase Domain. (2018) (6)
- Specialized Flavoprotein Promotes Sulfur Migration and Spiroaminal Formation in Aspirochlorine Biosynthesis. (2020) (6)
- Oak‐Associated Negativicute Equipped with Ancestral Aromatic Polyketide Synthase Produces Antimycobacterial Dendrubins (2020) (6)
- Electrochemical monitoring of ROS generation by anticancer agents: the case of chartreusin (2017) (5)
- Cell Chemical Biology: Home of Exciting Chemical Biology. (2016) (5)
- Food‐Poisoning Bacteria Employ a Citrate Synthase and a Type II NRPS To Synthesize Bolaamphiphilic Lipopeptide Antibiotics** (2020) (5)
- Horizontal gene transfer to a defensive symbiont with a reduced genome amongst a multipartite beetle microbiome (2019) (5)
- Identification and mobilization of a cryptic antibiotic biosynthesis gene locus from a human-pathogenic Nocardia isolate. (2019) (5)
- An Unexpected Split‐Merge Pathway in the Assembly of the Symmetric Nonribosomal Peptide Antibiotic Closthioamide (2020) (5)
- Bacterial marginolactones trigger formation of algal gloeocapsoids, protective aggregates on the verge of multicellularity (2021) (4)
- Photochemical oxazole-nitrile conversion downstream of rhizoxin biosynthesis and its impact on antimitotic activity. (2012) (4)
- Structural and Mechanistic Insights into C−S Bond Formation in Gliotoxin (2021) (4)
- Quercinol, an Antiinflammatory Chromene from the Wood-Rotting Fungus Daedalea quercina (Oak Mazegill). (2007) (4)
- ChemInform Abstract: Discovery of Clostrubin, an Exceptional Polyphenolic Polyketide Antibiotic from a Strictly Anaerobic Bacterium. (2014) (4)
- Structural investigation of the lipopolysaccharide O-chain isolated from Burkholderia fungorum strain DSM 17061. (2016) (4)
- ChemInform Abstract: Hydrazidomycins, Cytotoxic Alkylhydrazides from Streptomyces atratus. (2012) (4)
- Biosynthesis and Charging of Pyrrolysine, the 22nd Genetically Encoded Amino Acid (2012) (4)
- Zincophorin – biosynthesis in Streptomyces griseus and antibiotic properties (2016) (4)
- Serinal-derived vinyl oxiranes as novel and versatile building blocks for the stereoselective synthesis of D- and L-erythro-sphingosines (1998) (4)
- Bacterial cell wall-degrading enzymes induce basidiomycete natural product biosynthesis. (2021) (3)
- Structural and Conformational Study of the O‐Antigenic Portion of the Lipopolysaccharide Isolated from Burkholderia gladioli pv. cocovenenans (2016) (3)
- Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin (2010) (3)
- Bipiperidine conjugates as soluble sugar surrogates in DNA-intercalating antiproliferative polyketides. (2016) (3)
- Publisher Correction: Detection of antibiotics synthetized in microfluidic picolitre-droplets by various actinobacteria (2018) (3)
- Multimodal Molecular Imaging and Identification of Bacterial Toxins Causing Mushroom Soft Rot and Cavity Disease (2021) (3)
- Enzyme‐Primed Native Chemical Ligation Produces Autoinducing Cyclopeptides in Clostridia (2021) (3)
- Voices of Chemical Biology: Charting the Next Decade. (2016) (3)
- Serratia marcescens metabolites are promising candidates for biocontrol of avocado pathogens (2016) (3)
- Inside Cover: Ribosomal Synthesis of Tricyclic Depsipeptides in Bloom‐Forming Cyanobacteria (Angew. Chem. Int. Ed. 40/2008) (2008) (3)
- Genome Editing Reveals Novel Thiotemplated Assembly of Polythioamide Antibiotics in Anaerobic Bacteria (2018) (3)
- Cyclopropanol Warhead in Malleicyprol Confers Virulence of Human‐ and Animal‐Pathogenic Burkholderia Species (2019) (3)
- Enzymatic Thioamide Formation in a Bacterial Antimetabolite Pathway (2018) (3)
- Proof-Reading Thioesterase Boosts Activity of Engineered Nonribosomal Peptide Synthetase (2022) (2)
- Secreted TAL effectors protect symbiotic bacteria from entrapment within fungal hyphae (2020) (2)
- Assessment of Bioactivity‐Modulating Pseudo‐Ring Formation in Psilocin and Related Tryptamines (2022) (2)
- Alternative Benzoxazole Assembly Discovered in Anaerobic Bacteria Provides Access to Privileged Heterocyclic Scaffold (2022) (2)
- An intramodular thioesterase domain catalyses chain release in the biosynthesis of a cytotoxic virulence factor (2022) (2)
- Epicoccalone, a Coumarin‐Type Chymotrypsin Inhibitor, and Isobenzofuran Congeners from an Epicoccum sp. Associated with a Tree Fungus. (2008) (2)
- Functional modulation of chemical mediators in microbial communities. (2022) (2)
- Porcine pancreatic lipase (PPL) – a versatile biocatalyst in organic synthesis (1997) (2)
- Oxygenated Geosmins and Plant-like Eudesmanes from a Bacterial Mangrove Endophyte. (2020) (2)
- Plant-like Cadinane Sesquiterpenes from an Actinobacterial Mangrove Endophyte. (2020) (2)
- Fusaric acid detoxification: a strategy of Gliocladium roseum involved in its antagonism against Fusarium verticillioides (2022) (2)
- N‐Heterocyclization in Gliotoxin Biosynthesis is Catalyzed by a Distinct Cytochrome P450 Monooxygenase (2020) (2)
- Reconstitution of Iterative Thioamidation in Closthioamide Biosynthesis Reveals a Novel Nonribosomal Peptide Backbone‐Tailoring Strategy (2019) (2)
- Structure and Alignment of the Membrane-Associated Peptaibols Ampullosporin A and Alamethicin by Oriented 15 N and 31 P (2009) (2)
- Epicoccalone, a Coumarin‐Type Chymotrypsin Inhibitor, and Isobenzofuran Congeners from an Epicoccum sp. Associated with a Tree Fungus. (2008) (2)
- Bacterial ectosymbionts in cuticular organs chemically protect a beetle during molting stages (2022) (2)
- Efficient Gene Delivery of Tailored Amphiphilic Polypeptides by Polyplex Surfing. (2022) (2)
- Toxin-Producing Endosymbionts Shield Pathogenic Fungus against Micropredators (2022) (2)
- Draft Genome Sequence and Gene Annotation of the Entomopathogenic Fungus Verticillium hemipterigenum (2015) (2)
- B-methoxydiisopinocampheylborane (Ipc2BOMe): A pinene based auxiliary for asymmetric C-C bond-forming reactions (1999) (2)
- Isoflavones with Unusually Modified B‐Rings and Their Evaluation as Antiproliferative Agents. (2010) (1)
- Hygrobafilomycin, a Cytotoxic and Antifungal Macrolide Bearing a Unique Monoalkylmaleic Anhydride Moiety, from Streptomyces varsoviensis. (2010) (1)
- Author response: Targeted induction of a silent fungal gene cluster encoding the bacteria-specific germination inhibitor fumigermin (2020) (1)
- Induced Production, Synthesis, and Immunomodulatory Action of Clostrisulfone, a Diarylsulfone from Clostridium acetobutylicum (2020) (1)
- Natural 1,3‐Dipolar Cycloadditions (2015) (1)
- Frontispiz: Metal-Free Synthesis of Pharmaceutically Important Biaryls by Photosplicing (2018) (1)
- Rapid Screening of Polyol Polyketides from Marine Dinoflagellates (2022) (1)
- Fungal chromatin mapping identifies BasR, as the regulatory node of bacteria-induced fungal secondary metabolism (2018) (1)
- Bezerramycins A—C, Antiproliferative Phenoxazinones from Streptomyces griseus Featuring Carboxy, Carboxamide or Nitrile Substituents. (2010) (1)
- Author response: Chromatin mapping identifies BasR, a key regulator of bacteria-triggered production of fungal secondary metabolites (2018) (1)
- Fusaric acid detoxification: a strategy of Gliocladium roseum involved in its antagonism against Fusarium verticillioides (2022) (1)
- cterial phenazine forms S-conjugates with biogenic thiols and crosslinks proteins † (2016) (1)
- Cover Picture: Epidithiol Formation by an Unprecedented Twin Carbon–Sulfur Lyase in the Gliotoxin Pathway (Angew. Chem. Int. Ed. 40/2012) (2012) (1)
- Exploration of polyyne biosynthetic gene cluster diversity in bacteria leads to the discovery of the Pseudomonas polyyne protegencin (2021) (1)
- Titelbild: Epidithiol Formation by an Unprecedented Twin Carbon–Sulfur Lyase in the Gliotoxin Pathway (Angew. Chem. 40/2012) (2012) (1)
- A polyyne toxin produced by an antagonistic bacterium blinds and lyses a green microalga (2021) (1)
- Biosynthesis and Attachment of Novel Bacterial Polyketide Synthase Starter Units (2002) (1)
- Correction: Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis. (2021) (1)
- Sulfonium Acids Loaded onto an Unusual Thiotemplate Assembly Line Construct the Cyclopropanol Warhead of a Burkholderia Virulence Factor (2020) (1)
- Natural Products as Source of Therapeutics Against Parasitic Diseases (2016) (1)
- Evolution of Metabolic Diversity in Polyketide-Derived Pyrones: Using the Noncolinear Aureothin Assembly Line as a Model System. (2010) (1)
- Deciphering Chemical Mediators Regulating Specialized Metabolism in a Symbiotic Cyanobacterium (2022) (1)
- Author response: Active invasion of bacteria into living fungal cells (2014) (1)
- Bacterium-triggered remodeling of chromatin identifies BasR, a novel regulator of fungal natural product biosynthesis (2017) (1)
- On-Line Polyketide Cyclization into Diverse Medium-Sized Lactones by a Specialized Ketosynthase Domain (2018) (0)
- Cover Picture: Biosynthesis of the Antimetabolite 6‐Thioguanine in Erwinia amylovora Plays a Key Role in Fire Blight Pathogenesis (Angew. Chem. Int. Ed. 40/2013) (2013) (0)
- Biosynthesis and function of gliotoxin in Aspergillus fumigatus (2011) (0)
- A Photochemical Macrocyclization Route to Asymmetric Strained [3.2] Paracyclophanes (2022) (0)
- Summaries Petersen / Amstutz ( eds ) : Natural Compounds as Drugs (2017) (0)
- An antifungal polyketide associated with horizontally acquired genes supports symbiont-mediated defense in Lagria villosa beetles (2018) (0)
- Nebularic Acids and Nebularilactones, Novel Drimane Sesquiterpenoids from the Fungus Lepista nebularis. (2006) (0)
- Ecological Niche-Inspired Genome Mining Leads to the Discovery of Crop-Protecting Nonribosomal Lipopeptides Featuring a Transient Amino Acid Building Block. (2023) (0)
- Serinal-Derived Vinyl Oxiranes as Novel and Versatile Building Blocks for the Stereoselective Synthesis of D- and L-erythro-Sphingosines. (1999) (0)
- Faculty Opinions recommendation of Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides. (2012) (0)
- CCDC 1406841: Experimental Crystal Structure Determination (2017) (0)
- Thalictramine, A new alkaloid from Thalictrum rhyncocarpum (Dill & Rich) and its anti-bacterial activity (2014) (0)
- Bovine trypsin in complex with microviridin J at pH 6.5 (2014) (0)
- Crystal structure of CerJ from Streptomyces tendae in Complex with CoA (2011) (0)
- Mapping Natural Dyes in Archeological Textiles by Imaging Mass Spectrometry (2019) (0)
- Titelbild: Biosynthesis of the Halogenated Mycotoxin Aspirochlorine in Koji Mold Involves a Cryptic Amino Acid Conversion (Angew. Chem. 49/2014) (2014) (0)
- Structure And Alignment Of Membrane-associated Peptaibols By Oriented 15N And 31P Solid-state NMR Spectroscopy (2009) (0)
- Crystal structure of DepH (2014) (0)
- Recent approaches using alkenyl-oxiranes in organic synthesis (2000) (0)
- Innentitelbild: Ribosomal Synthesis of Tricyclic Depsipeptides in Bloom‐Forming Cyanobacteria (Angew. Chem. 40/2008) (2008) (0)
- Anaerobic bacteria as producers of antibiotics (2012) (0)
- XiaF (FADH2) from Streptomyces sp. (2017) (0)
- A Specialized Polythioamide‐Binding Protein Confers Antibiotic Self‐Resistance in Anaerobic Bacteria (2022) (0)
- Squarrosidine and Pinillidine: 3,3′-Fused Bis(styrylpyrones) from Pholiota squarrosa and Phellinus pini. (2007) (0)
- Antiinflammatory and Antihyaluronate Lyase Activities of Lanostanoids from Piptoporus betulinus. (2005) (0)
- From Powerful Review Articles to Research Breakthroughs. (2016) (0)
- Endofungal bacteria boost anthelminthic host protection with the biosurfactant symbiosin (2022) (0)
- Exploiting gene regulation as an approach to identify , analyze and utilize the biosynthetic pathways of the glycopeptide ristomycin A and the zincophore [ S , S ]-EDDS in Amycolatopsis japonicum (2017) (0)
- Crystal structure of HlmI (2014) (0)
- Author response: Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals (2015) (0)
- Porcine Pancreatic Lipase (PPL). A Versatile Biocatalyst in Organic Synthesis (1997) (0)
- Titelbild: Convergent Asymmetric Synthesis of (+)‐Aureothin Employing an Oxygenase‐Mediated Resolution Step (Angew. Chem. 38/2012) (2012) (0)
- Enterococcus mundtii controls the development of the gut microbiome in the lepidoteran Spodoptera littoralis (2016) (0)
- Titelbild: Polyketide‐Chain Branching by an Enzymatic Michael Addition (Angew. Chem. 27/2009) (2009) (0)
- Detection of antibiotics synthetized in microfluidic picolitre-droplets by various actinobacteria (2018) (0)
- Structural and Mechanistic Insights into C (cid:2) S Bond Formation in Gliotoxin in the (2021) (0)
- A highly conserved gene locus in endofungal bacteria codes for the biosynthesis of symbiosis-specific cyclopeptides (2022) (0)
- Reply to Oren et al., “New Phylum Names Harmonize Prokaryotic Nomenclature” (2022) (0)
- Cover Picture: Biosynthesis of the Halogenated Mycotoxin Aspirochlorine in Koji Mold Involves a Cryptic Amino Acid Conversion (Angew. Chem. Int. Ed. 49/2014) (2014) (0)
- A Type III Polyketide Synthase Specific for Sporulating Negativicutes is Responsible for Alkylpyrone Biosynthesis (2022) (0)
- Crystal Structure of the Cytochrome P450 Monooxygenase AurH from Streptomyces Thioluteus in Complex with Ancymidol (2011) (0)
- Antagonistic bacteria disrupt calcium homeostasis and immobilize algal cells (2017) (0)
- Sequential Allylic Alcohol Formation by a Multifunctional Cytochrome P450 Monooxygenase with Rare Redox Partners (2022) (0)
- Structure of the N-oxygenase AurF from Streptomyces thioluteus (2007) (0)
- Cover Feature: N‐Heterocyclization in Gliotoxin Biosynthesis is Catalyzed by a Distinct Cytochrome P450 Monooxygenase (ChemBioChem 2/2021) (2021) (0)
- Crystal structure of GliT (2014) (0)
- Terpenoid Biosynthesis off the Beaten Track: Unconventional Cyclases and Their Impact on Biomimetic Synthesis (2015) (0)
- Faculty Opinions recommendation of Environmental control of the calicheamicin polyketide synthase leads to detection of a programmed octaketide and a proposal for enediyne biosynthesis. (2013) (0)
- Crystal Structure of CerJ from Streptomyces tendae (2011) (0)
- Decoding and reprogramming complex biosynthetic pathways in microbes (2015) (0)
- Frontispiece: Metal-Free Synthesis of Pharmaceutically Important Biaryls by Photosplicing (2018) (0)
- Author response: Highly parallelized droplet cultivation and prioritization of antibiotic producers from natural microbial communities (2021) (0)
- Our Advisors, Our Ambassadors, Our Editorial Board Members. (2016) (0)
- Cover Picture: Polyketide-Chain Branching by an Enzymatic Michael Addition (Angew. Chem. Int. Ed. 27/2009) (2009) (0)
- Faculty Opinions recommendation of Metabolomics enables the structure elucidation of a diatom sex pheromone. (2013) (0)
- Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria (2014) (0)
- Publisher Correction: Detection of antibiotics synthetized in microfluidic picolitre-droplets by various actinobacteria (2018) (0)
- Inside Cover: Rational Design of an Apoptosis‐Inducing Photoreactive DNA Intercalator (Angew. Chem. Int. Ed. 24/2013) (2013) (0)
- Microfluidics Reveals Trapping of Endosymbiotic Bacteria Inside a Fungus (2021) (0)
- ChemInform Abstract: Reductive Chloro- and Thioallylations: Stereoselective Two-Step Transformations of Esters and Lactones into Functionalized cis- and trans-Vinyloxiranes. (1999) (0)
- The Chemistry and Biology of Cytochalasans (2010) (0)
- B-Methoxydiisopinocampheylborane (Ipc2BOMe): A Pinene Based Auxiliary for Asymmetric C—C Bond-Forming Reactions (1999) (0)
- Faculty Opinions recommendation of Biosynthesis of the structurally unique polycyclopropanated polyketide-nucleoside hybrid jawsamycin (FR-900848). (2014) (0)
- Chemoenzymatic Total Synthesis of the Antiproliferative Polyketide (+)-(R)-Aureothin. (2008) (0)
- Lichen-like association of Chlamydomonas reinhardtii and Aspergillus nidulans protects algal cells from bacteria (2020) (0)
- Natural products from reconstructed bacterial genomes of the Middle and Upper Paleolithic. (2023) (0)
- Crystal structure of CerJ from Streptomyces tendae soaked with CerviK (2011) (0)
- Faculty Opinions recommendation of Formation of 1,3-cyclohexanediones and resorcinols catalyzed by a widely occurring ketosynthase. (2014) (0)
- Crystal Structure of the Cytochrome P450 Monooxygenase AurH (nterm-AurH-I) from Streptomyces Thioluteus (2011) (0)
- Cervimycin-Resistant Staphylococcus aureus Strains Display Vancomycin-Intermediate Resistant Phenotypes (2022) (0)
- Reflecting on the past and looking forward to the future of bridging chemistry and biology. (2014) (0)
- Faculty Opinions recommendation of Biosynthetic pathway toward carbohydrate-like moieties of alnumycins contains unusual steps for C-C bond formation and cleavage. (2012) (0)
- CervimycinC resistance inBacillus subtilis is due toa promoter up-mutationand increasedmRNA stabilityofthe constitutive ABC-transportergenebmrA (2010) (0)
- Highly Efficient Synthesis of (.+-.)-Lamoxirene, the Gamete-Releasing and Gamete-Attracting Pheromone of the Laminariales (Phaeophyta). (1998) (0)
- Enzymatic Amide Tailoring Promotes Retro-Aldol Amino Acid Conversion To Form the Antifungal Agent Aspirochlorine (2018) (0)
- Innentitelbild: Rational Design of an Apoptosis‐Inducing Photoreactive DNA Intercalator (Angew. Chem. 24/2013) (2013) (0)
- Type II Polyketide Synthases: Gaining a Deeper Insight into Enzymatic Teamwork (2007) (0)
- Tandem Reduction—Chloroallylboration of Esters: Asymmetric Synthesis of Lamoxirene, the Spermatozoid Releasing and Attracting Pheromone of the Laminariales (Phaeophyceae). (2000) (0)
- Chemical warfare between leafcutter ant symbionts and a co-evolved pathogen (2018) (0)
- Cover Picture: Cervimycin A–D: A Polyketide Glycoside Complex from a Cave Bacterium Can Defeat Vancomycin Resistance (Chem. Eur. J. 19/2005) (2005) (0)
- Ubiquitous bacterial polyketides induce cross-kingdom microbial interactions (2022) (0)
- Sustainable and highly controlled aryl couplings revealed by systematic assessment of photoactivatable linkers (2022) (0)
- XiaF (apo) from Streptomyces sp. (2017) (0)
- nidulansMetabolism in Aspergillus Distinct Amino Acids of Histone H3 Control (2014) (0)
- XiaF from Streptomyces sp. in complex with FADH2 and Glycerol (2017) (0)
- Thiotemplated Biosynthesis of Bacterial Polyyne Fatty Acids by a Designated Desaturase Triad (2022) (0)
- The Biosynthetic Logic of Polyketide Diversity (2009) (0)
- Crystal structure of AclR, a thioredoxin oxidoreductase fold protein carrying the CXXH catalytic motif (2020) (0)
- Asymmetric α-Chloroallylboration of Amino Aldehydes: A Novel and Highly Versatile Route to D- and L-erythro-Sphingoid Bases. (2010) (0)
- Highly Efficient Total Synthesis of the Clostridium‐Derived anti‐MRSA Antibiotic Closthioamide (Eur. J. Org. Chem. 8/2011) (2011) (0)
- Crystal structure of CerJ from Streptomyces tendae - malonic acid covalently linked to the catalytic Cystein C116 (2011) (0)
- Bovine trypsin in complex with microviridin J at pH 8.5 (2014) (0)
- Cover Picture: Convergent Asymmetric Synthesis of (+)‐Aureothin Employing an Oxygenase‐Mediated Resolution Step (Angew. Chem. Int. Ed. 38/2012) (2012) (0)
- Eukaryotic Polyketides in Surrogate Hosts (EUKETIDES). (2004) (0)
- Titelbild: Biosynthesis of the Antimetabolite 6-Thioguanine in Erwinia amylovora Plays a Key Role in Fire Blight Pathogenesis (Angew. Chem. 40/2013) (2013) (0)
- Cover Picture: Biosynthesis of the Antimetabolite 6‐Thioguanine in Erwinia amylovora Plays a Key Role in Fire Blight Pathogenesis (Angew. Chem. Int. Ed. 40/2013) (2013) (0)
- Discovery of Amidotemplated Natural Product Assembly. (2019) (0)
- Peptide splicing is a prevalent biosynthetic strategy for installing β-amino acid pharmacophores (2022) (0)
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