Christine Harrison | Academic Influence

Christine Harrison's AcademicInfluence.com Rankings

Christine Harrison

Computer Science

#6432

World Rank

#6782

Historical Rank

Machine Learning

#2086

World Rank

#2113

Historical Rank

Artificial Intelligence

#2346

World Rank

#2386

Historical Rank

Database

#3520

World Rank

#3667

Historical Rank

computer-science Degrees

Download Badge

Computer Science

Christine Harrison's Degrees

PhD Computer Science Stanford University
Masters Artificial Intelligence University of California, Berkeley

Similar Degrees You Can Earn

Why Is Christine Harrison Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Christine J. Harrison is a Professor of Childhood Cancer Cytogenetics at Newcastle University. She works on acute leukemia and used cytogenetics to optimise treatment protocols. Early life and education Harrison attended an all girls school, where she was encouraged to become a nurse or a teacher. Harrison went to work at GlaxoSmithKline, before returning to education and securing her A-Levels. She was appointed as a research technician at the Paterson Institute for Cancer Research. She was encouraged to attend university, and studied zoology at the University of Manchester. She remained there for her postgraduate studies, and earned a PhD in cell biology in 1978. During her postgraduate degree Harrison became interested in cytogenetics.

(See a Problem?)

Christine Harrison's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. (1998) (2740)
Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. (2010) (1676)
Acute lymphoblastic leukaemia. (2011) (1244)
The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial. (2001) (927)
Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial. (2005) (684)
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. (2009) (479)
A simple, robust, validated and highly predictive index for the determination of risk‐directed therapy in acute myeloid leukaemia derived from the MRC AML 10 trial (1999) (444)
Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial. (2010) (365)
Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group. (2010) (312)
The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms (2022) (293)
Treatment strategy and long-term results in paediatric patients treated in consecutive UK AML trials (2005) (289)
Cytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment trials AML 10 and 12. (2010) (275)
PHF6 mutations in T-cell acute lymphoblastic leukemia (2010) (264)
Outcome of treatment in children with hypodiploid acute lymphoblastic leukemia. (2007) (256)
Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk (2010) (253)
Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL. (2013) (245)
Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements (2003) (241)
Localization of the estrogen receptor locus (ESR) to chromosome 6q25.1 by FISH and a simple post-FISH banding technique. (1993) (232)
Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study. (2009) (225)
Burkitt's lymphoma (2012) (225)
Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia (2014) (224)
Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia (2009) (209)
Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). (2007) (205)
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition. (2013) (204)
Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemia (2004) (200)
Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21). (2007) (199)
A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups. (2009) (192)
Outcome heterogeneity in childhood high-hyperdiploid acute lymphoblastic leukemia. (2003) (182)
Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia. (2009) (179)
A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia. (2014) (178)
Results of a randomized trial in children with Acute Myeloid Leukaemia: Medical Research Council AML12 trial (2011) (175)
An international study of intrachromosomal amplification of chromosome 21 (iAMP21): cytogenetic characterization and outcome (2014) (163)
Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases (2003) (163)
Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: an iBFM-SG study. (2008) (161)
Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma (2006) (158)
Interphase molecular cytogenetic screening for chromosomal abnormalities of prognostic significance in childhood acute lymphoblastic leukaemia: a UK Cancer Cytogenetics Group Study (2005) (148)
Cytogenetics and molecular genetics of acute lymphoblastic leukemia. (2002) (148)
Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21. (2006) (147)
Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial. (2011) (142)
Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia. (2008) (141)
Monosomy 7 and deletion 7q in children and adolescents with acute myeloid leukemia: an international retrospective study. (2007) (138)
Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features (2013) (133)
High-dose therapy and autologous stem-cell support for chemosensitive transformed low-grade follicular non-Hodgkin's lymphoma: a case-matched study from the European Bone Marrow Transplant Registry. (2001) (130)
IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL. (2014) (129)
Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol (2001) (127)
Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia (2015) (126)
INVESTIGATION OF MINIMAL RESIDUAL DISEASE IN CHILDHOOD AND ADULT ACUTE LYMPHOBLASTIC LEUKAEMIA BY MOLECULAR ANALYSIS (1999) (125)
Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome (2003) (114)
Evaluation of multiplex ligation‐dependent probe amplification as a method for the detection of copy number abnormalities in B‐cell precursor acute lymphoblastic leukemia (2010) (110)
Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization (2007) (108)
IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia. (2012) (107)
Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia (2017) (106)
Detection of prognostically relevant genetic abnormalities in childhood B‐cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin‐Frankfürt‐Münster study group (2010) (105)
Risk-directed treatment intensification significantly reduces the risk of relapse among children and adolescents with acute lymphoblastic leukemia and intrachromosomal amplification of chromosome 21: a comparison of the MRC ALL97/99 and UKALL2003 trials. (2013) (105)
Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia. (2011) (104)
Long-term follow-up of the United Kingdom Medical Research Council protocols for childhood acute Lymphoblastic leukaemia, 1980–2001 (2009) (103)
Prenatal origin of hyperdiploid acute lymphoblastic leukemia in identical twins (2003) (98)
EBF1-PDGFRB fusion in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): genetic profile and clinical implications. (2016) (98)
Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukemia. (2016) (97)
Refinement of cytogenetic classification in acute myeloid leukaemia: Determination of prognostic significance of rarer recurring chromosomal abnormalities amongst 5,876 younger adult patients treated in the UK Medical Research Council trials (2010) (97)
The fragile X: a scanning electron microscope study. (1983) (96)
Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations (2012) (94)
Molecular tracking of leukemogenesis in a triplet pregnancy. (2001) (93)
The t(14;20) is a poor prognostic factor in myeloma but is associated with long-term stable disease in monoclonal gammopathies of undetermined significance (2010) (91)
A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia (2010) (90)
Genetic aberrations in paediatric acute leukaemias and implications for management of patients. (2010) (90)
Detection of CBFB/MYH11 transcripts in patients with inversion and other abnormalities of chromosome 16 at presentation and remission (1995) (90)
Variable breakpoints target PAX5 in patients with dicentric chromosomes: A model for the basis of unbalanced translocations in cancer (2008) (89)
Prognostic significance of the balanced t(1;19) and unbalanced der(19)t(1;19) translocations in acute lymphoblastic leukemia. (1992) (89)
Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia. (2010) (89)
Blood Spotlight on iAMP21 acute lymphoblastic leukemia (ALL), a high-risk pediatric disease. (2015) (87)
The Leukaemia Research Fund/United Kingdom Cancer Cytogenetics Group Karyotype Database in acute lymphoblastic leukaemia: a valuable resource for patient management (2001) (87)
Chronic myeloid leukemia: reminiscences and dreams (2016) (87)
Secondary cytogenetic aberrations in childhood Philadelphia chromosome positive acute lymphoblastic leukemia are nonrandom and may be associated with outcome (2004) (86)
Successful treatment without cranial radiotherapy of children receiving intensified chemotherapy for acute lymphoblastic leukaemia: results of the risk‐stratified randomized central nervous system treatment trial MRC UKALL XI (ISRC TN 16757172) (2004) (83)
Timing of acquisition of deletion 13 in plasma cell dyscrasias is dependent on genetic context (2009) (80)
Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia. (2006) (77)
Treatment of infants with lymphoblastic leukaemia: results of the UK Infant Protocols 1987–1999 (2002) (76)
The detection and significance of chromosomal abnormalities in childhood acute lymphoblastic leukaemia. (2001) (75)
IGH@ translocations are prevalent in teenagers and young adults with acute lymphoblastic leukemia and are associated with a poor outcome. (2014) (75)
High-resolution scanning electron microscopy of human metaphase chromosomes. (1982) (72)
Age has a profound effect on the incidence and significance of chromosome abnormalities in myeloma (2005) (71)
Cell migration through three-dimensional gels of native collagen fibres: collagenolytic activity is not required for the migration of two permanent cell lines. (1980) (69)
Common region of deletion on the long arm of chromosome 6 in non‐Hodgkin's lymphoma and acute lymphoblastic leukaemia (1994) (69)
Frequent upregulation of MYC in plasma cell leukemia (2009) (69)
Intrachromosomal amplification of chromosome 21 (iAMP21) may arise from a breakage–fusion–bridge cycle (2007) (69)
Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group. (2012) (69)
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling (2015) (69)
Scanning electron microscopy of the G-banded human karyotype. (1981) (69)
Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Münster Study Group. (2015) (68)
Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia (2009) (67)
Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia (2010) (67)
Translocations of 14q32 and deletions of 13q14 are common chromosomal abnormalities in systemic amyloidosis (2002) (66)
t(6;9)(p22;q34)/DEK-NUP214-rearranged pediatric myeloid leukemia: an international study of 62 patients (2014) (66)
The complex genomic profile of ETV6‐RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1 (2008) (65)
t(7;12)(q36;p13), a new recurrent translocation involving ETV6 in infant leukemia (2000) (65)
Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study. (2011) (65)
t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). (2008) (65)
A novel translocation, t(14;19)(q32;p13), involving IGH@ and the cytokine receptor for erythropoietin (2009) (60)
Abnormal cytogenetic clones in patients with aplastic anaemia: response to immunosuppressive therapy (1999) (60)
Amplification of the ABL gene in T-cell acute lymphoblastic leukemia (2004) (59)
Use of Minimal Residual Disease Assessment to Redefine Induction Failure in Pediatric Acute Lymphoblastic Leukemia. (2017) (58)
Molecular cytogenetic characterization of TCF3 (E2A)/19p13.3 rearrangements in B‐cell precursor acute lymphoblastic leukemia (2007) (57)
Near haploid acute lymphoblastic leukemia: seven new cases and a review of the literature. (1991) (57)
Deletion of 6q16-q21 in human lymphoid malignancies: a mapping and deletion analysis. (2000) (56)
Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: sequential analysis of a single case (2009) (55)
Heterogeneous breakpoints in patients with acute lymphoblastic leukemia and the dic(9;20)(p11~13;q11) show recurrent involvement of genes at 20q11.21 (2009) (55)
Loss of chromosomes is the primary event in near-haploid and low-hypodiploid acute lymphoblastic leukemia (2013) (53)
The T-cell leukemia associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling (2017) (51)
Targeting signaling pathways in acute lymphoblastic leukemia: new insights. (2013) (51)
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2018) (50)
Outcome of Children With Hypodiploid Acute Lymphoblastic Leukemia: A Retrospective Multinational Study. (2019) (47)
Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations. (2014) (45)
MRC trials in childhood acute myeloid leukaemia. (2004) (44)
Treatment outcome of CRLF2 ‐rearranged childhood acute lymphoblastic leukaemia: a comparative analysis of the AIEOP‐BFM and UK NCRI‐CCLG study groups (2012) (43)
The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial (2013) (42)
Characterisation of the genomic landscape of CRLF2‐rearranged acute lymphoblastic leukemia (2017) (42)
The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL (2018) (42)
A Fluorescence in Situ Hybridization Map of 6q Deletions in Acute Lymphocytic Leukemia (2004) (41)
Del (9q) AML: clinical and cytological characteristics and prognostic implications (2005) (41)
Deletion of a common region on the long arm of chromosome 6 in acute lymphoblastic leukaemia (1994) (40)
Fluorescence in situ hybridization analysis of masked (8;21)(q22;q22) translocations. (1999) (40)
Hyperdiploidy with 49–65 chromosomes represents a heterogeneous cytogenetic subgroup of acute myeloid leukemia with differential outcome (2014) (37)
Derivative chromosome 9 deletions are a significant feature of childhood Philadelphia chromosome positive acute lymphoblastic leukaemia (2005) (37)
Validation of the United Kingdom copy-number alteration classifier in 3239 children with B-cell precursor ALL. (2019) (37)
Advances in B-cell Precursor Acute Lymphoblastic Leukemia Genomics (2018) (37)
The role of the RAS pathway in iAMP21-ALL (2016) (36)
Cytogenetics of multiple myeloma: interpretation of fluorescence in situ hybridization results (2003) (35)
Dicentric (9;12) in acute lymphocytic leukemia and other hematological malignancies: report from a dic(9;12) study group. (1995) (35)
THE MANAGEMENT OF PATIENTS WITH LEUKAEMIA: THE ROLE OF CYTOGENETICS IN THIS MOLECULAR ERA (2000) (33)
Scanning electron microscopy of variations in human metaphase chromosome structure revealed by Giemsa banding. (1983) (33)
Comparative expressed sequence hybridization studies of high‐hyperdiploid childhood acute lymphoblastic leukemia (2004) (33)
High hyperdiploidy among adolescents and adults with acute lymphoblastic leukaemia (ALL): cytogenetic features, clinical characteristics and outcome (2014) (33)
The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia (2015) (32)
Analysis of chromosome 6 deletions in lymphoid malignancies provides evidence for a region of minimal deletion within a 2-megabase segment of 6q21 (1997) (31)
Analysis of a breakpoint cluster reveals insight into the mechanism of intrachromosomal amplification in a lymphoid malignancy. (2011) (31)
Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia (2015) (31)
Tracheal granulation tissue. A study of bacteriology. (1991) (29)
c-MYC is a radiosensitive locus in human breast cells (2014) (29)
Methylation of tumour suppressor gene promoters in the presence and absence of transcriptional silencing in high hyperdiploid acute lymphoblastic leukaemia (2009) (29)
t(14;19)(q32;q13): A recurrent translocation in B‐cell precursor acute lymphoblastic leukemia (2004) (29)
Retinoblastoma in association with the chromosome breakage syndromes Fanconi's anaemia and Bloom's syndrome: clinical and cytogenetic findings (1995) (28)
HUGO Gene Nomenclature Committee (HGNC) recommendations for the designation of gene fusions (2021) (28)
Digital Multiplex Ligation-Dependent Probe Amplification for Detection of Key Copy Number Alterations in T- and B-Cell Lymphoblastic Leukemia. (2017) (26)
Philadelphia‐positive metaphases in the marrow after bone marrow transplantation for chronic granulocytic leukemia (1986) (26)
Clinical characteristics and outcomes of B-ALL with ZNF384 rearrangements: a retrospective analysis by the Ponte di Legno Childhood ALL Working Group (2021) (26)
Unlocking the potential of anti-CD33 therapy in adult and childhood acute myeloid leukemia. (2017) (26)
S828 A RANDOMIZED, DOUBLE BLIND PHASE 2 STUDY OF 3 DIFFERENT DOSES OF PRM-151 IN PATIENTS WITH MYELOFIBROSIS WHO WERE PREVIOUSLY TREATED WITH OR INELIGIBLE FOR RUXOLITINIB (2019) (26)
Impact of karyotype on treatment outcome in acute myeloid leukemia. (2004) (25)
Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia. (2012) (25)
No prognostic effect of additional chromosomal abnormalities in children with acute lymphoblastic leukemia and 11q23 abnormalities (2005) (25)
Translocations involving 12p in acute myeloid leukemia: Association with prior myelodysplasia and exposure to mutagenic agents (1992) (25)
Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL. (2018) (25)
The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A (2015) (25)
Constitutional abnormalities of chromosome 21 predispose to iAMP21-acute lymphoblastic leukaemia. (2016) (25)
Analysis of ETV6/AML1 abnormalities in acute lymphoblastic leukaemia: incidence, alternative spliced forms and minimal residual disease value (2000) (25)
Postnatal encephaloclastic porencephaly--a new lesion? (1992) (24)
Chromosomal translocations involving the IGH@ locus in B-cell precursor acute lymphoblastic leukemia: 29 new cases and a review of the literature. (2013) (24)
Structural abnormalities of the X chromosome in non-Hodgkin's lymphoma. (1993) (24)
Multiplex fluorescence in situ hybridization and cross species color banding of a case of chronic myeloid leukemia in blastic crisis with a complex Philadelphia translocation. (2000) (24)
Cytogenetics of Pediatric Acute Myeloid Leukemia: A Review of the Current Knowledge (2021) (24)
The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia (2018) (23)
Adjuvant tyrosine kinase inhibitor therapy improves outcome for children and adolescents with acute lymphoblastic leukaemia who have an ABL‐class fusion (2020) (23)
Translocations involving 9p and/or 12p in acute lymphoblastic leukemia (1992) (23)
Abnormalities of the der(12)t(12;21) in ETV6‐RUNX1 acute lymphoblastic leukemia (2013) (22)
Cytogenetics and outcome of infants with acute lymphoblastic leukemia and absence of MLL rearrangements (2013) (22)
IGH@ translocations co-exist with other primary rearrangements in B-cell precursor acute lymphoblastic leukemia (2014) (22)
Extended Data Figure 5 (2014) (22)
MLL translocations with concurrent 3′ deletions: Interpretation of FISH results (2004) (22)
Cross‐species color banding in ten cases of myeloid malignancies with complex karyotypes (2001) (21)
The genetics of childhood acute lymphoblastic leukaemia. (2000) (21)
Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study (2021) (20)
Specific JAK 2 mutation ( JAK 2 R 683 ) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia (2009) (20)
Analysis of balanced rearrangements of chromosome 6 in acute leukemia: clustered breakpoints in q22-q23 and possible involvement of c-MYB in a new recurrent translocation, t(6;7)(q23;q32 through 36). (2005) (20)
Long-term follow-up of ETV6–RUNX1 ALL reveals that NCI risk, rather than secondary genetic abnormalities, is the key risk factor (2013) (20)
Cell surface morphology after trypsinisation depends on initial cell shape. (1979) (20)
SH2B3 inactivation through CN-LOH 12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain (2019) (20)
ETV6/RUNX1 fusion at diagnosis and relapse: Some prognostic indications (2005) (20)
Intragenic amplification of PAX5: a novel subgroup in B-cell precursor acute lymphoblastic leukemia? (2017) (20)
Complex chromosomal abnormalities in utero, 5 years before leukaemia * (2004) (19)
Light and scanning electron microscopy of the same human metaphase chromosomes. (1985) (19)
14q32 rearrangements deregulating BCL11B mark a distinct subgroup of T and myeloid immature acute leukemia. (2021) (19)
Refinement of IKZF1 status in pediatric Philadelphia-positive acute lymphoblastic leukemia (2015) (19)
Prognostic impact of chromosomal abnormalities and copy number alterations in adult B-cell precursor acute lymphoblastic leukaemia: a UKALL14 study (2021) (18)
Disruption of ETV6 in intron 2 results in upregulatory and insertional events in childhood acute lymphoblastic leukaemia (2008) (18)
A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia. (2020) (17)
A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia (2017) (17)
A scanning electron microscopy study of double minutes from a human tumour cell line. (1987) (17)
Is trisomy 5 a distinct cytogenetic subgroup in acute lymphoblastic leukemia? (2004) (17)
Modeling the molecular consequences of unbalanced translocations in cancer: Lessons from acute lymphoblastic leukemia (2009) (16)
Involvement of the MLL gene in T-lineage acute lymphoblastic leukemia. (2002) (16)
The B-13 hepatocyte progenitor cell resists pluripotency induction and differentiation to non-hepatocyte cells (2013) (16)
Acute lymphoblastic leukaemia. (2001) (15)
Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia (2016) (15)
A Fluorescence in Situ Hybridization Map of 6q Deletions in Acute Lymphocytic Leukemia: Identification and Analysis of a Candidate Tumor Suppressor Gene (2004) (15)
Remission, treatment failure, and relapse in pediatric ALL: An international consensus of the Ponte-di-Legno Consortium. (2021) (15)
Scanning electron microscopy of human metaphase chromosomes. (1986) (14)
HLA-DPB1 supertype-associated protection from childhood leukaemia: relationship to leukaemia karyotype and implications for prevention (2007) (14)
Distinct patterns of gained chromosomes in high hyperdiploid acute lymphoblastic leukemia with t(1;19)(q23;p13), t(9;22)(q34;q22) or MLL rearrangements (2013) (14)
CREBBP knockdown enhances RAS/RAF/MEK/ERK signaling in Ras pathway mutated acute lymphoblastic leukemia but does not modulate chemotherapeutic response (2016) (14)
REFINEMENT OF CYTOGENETIC CLASSIFICATION IN AML: DETERMINATION OF PROGNOSTIC SIGNIFICANCE OF RARE RECURRING CHROMOSOMAL ABNORMALITIES AMONGST 5635 YOUNGER ADULTS TREATED IN THE UK MRC TRIALS (2009) (12)
Catalog of Chromosome Aberrations in Cancer (1992) (12)
Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re‐sensitization by JNK inhibition (2015) (12)
Acute lymphoblastic leukemia. (2011) (11)
The structural basis for C-banding. A scanning electron microscopy study. (1985) (11)
Baller Gerold syndrome and Fanconi anaemia. (1998) (11)
Defining low-risk high hyperdiploidy in patients with paediatric acute lymphoblastic leukaemia: a retrospective analysis of data from the UKALL97/99 and UKALL2003 clinical trials (2021) (11)
Impact of diagnostic cytogenetics on outcome in AML: Analysis of 1,613 patients entered into the UK MRC AML 10 trial. (1996) (11)
A cell line from Wilms' tumour with deletion in short arm of chromosome 11 (1987) (11)
Cancer Cytogenetics: Chromosomal and Molecular Genetic Aberrations of Tumour Cells, 2nd edn (1997) (11)
10 – Light and Scanning Electron Microscopy of the Same Metaphase Chromosomes (1987) (11)
Wolff-Parkinson-White syndrome in an infant. (1952) (10)
MYELODYSPLASIA PRESENTING AS AUTOIMMUNE HAEMOLYTIC ANAEMIA (1991) (10)
Key pathways as therapeutic targets (2011) (10)
Three cases of the myelodysplastic syndrome with pericentric inversion of chromosome 16 (1993) (10)
Analysis of balanced rearrangements of chromosome 6 in acute leukemia : clustered breakpoints in q 22-q 23 and possible involvement of c-MYB in a new recurrent translocation (2005) (10)
MLPA and DNA index improve the molecular diagnosis of childhood B-cell acute lymphoblastic leukemia (2020) (10)
A chromosome 14q11/TCR alpha/delta specific yeast artificial chromosome improves the detection rate and characterization of chromosome abnormalities in T-lymphoproliferative disorders. (1997) (10)
Design of a comprehensive fluorescence in situ hybridization assay for genetic classification of T-cell acute lymphoblastic leukemia. (2020) (10)
The karyotype of Alligator mississippiensis, and chromosomal mapping of the ZFY/X homologue, Zfc (1994) (10)
A multicenter evaluation of comprehensive analysis of MLL translocations and fusion gene partners in acute leukemia using the MLL FusionChip device. (2007) (9)
Brief report t ( 6 ; 14 ) ( p 22 ; q 32 ) : a new recurrent IGH @ translocation involving ID 4 in B-cell precursor acute lymphoblastic leukemia ( BCP-ALL ) (2007) (9)
Human Chromosomes: Structure, Behaviour, Effects (1982) (9)
Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21 (2018) (9)
Acute lymphoblastic leukaemia following Hodgkin's disease is associated with a good prognosis (1994) (9)
Fine-structural aspects of bromodeoxyuridine incorporation in sister chromatid differentiation and replication banding. (1989) (9)
Genetic characterization and therapeutic targeting of MYC‐rearranged T cell acute lymphoblastic leukaemia (2018) (8)
A Fluorescence in Situ Hybridization Map of 6 q Deletions in Acute Lymphocytic Leukemia : Identification and Analysis of a Candidate Tumor Suppressor Gene (2004) (8)
Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma (2021) (8)
PCR amplicons identify widespread copy number variation in human centromeric arrays and instability in cancer (2021) (8)
Epigenetic regulator genes direct lineage switching in MLL-AF4 leukaemia (2021) (8)
BTG1 deletions do not predict outcome in Down syndrome acute lymphoblastic leukemia (2013) (8)
The prognostic significance of trisomy 4 in acute myeloid leukaemia is dependent on age and additional abnormalities (2016) (8)
Evaluation of RIDA®GENE norovirus GI/GII real time RT-PCR using stool specimens collected from children and adults with acute gastroenteritis. (2018) (8)
Conventional therapeutic options have limited impact on MPN symptoms: Insights from a prospective analysis of the MPN-SAF TSS (2012) (7)
Gain of 1q21 Does Not Predict for Immediate Progression in MGUS. (2009) (7)
A structural basis for R- and T-banding: a scanning electron microscopy study (2004) (7)
The importance of cytogenetics and associated molecular techniques in the management of patients with leukaemia. (1998) (7)
Single nucleotide polymorphism array‐based signature of low hypodiploidy in acute lymphoblastic leukemia (2021) (7)
Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia (2020) (6)
Karyotype is an independent prognostic factor in adult acute lymphoblastic leukaemia (2007) (6)
Gene mapping data – recommendations for more efficient dissemination (1983) (6)
Alveolar rhabdomyosarcoma with del(13q14). (1991) (6)
The structural basis for C-banding (2004) (6)
ELEVATED RED CELL ADENOSINE DEAMINASE AND HAEMOLYSIS IN A PATIENT WITH A MYELODYSPLASTIC SYNDROME (1989) (6)
Influence of 12‐o‐tetradecanoylphorbol‐13‐acetate (TPA) on the susceptibility of K562 to natural cytotoxicity: Evidence for clonal variation in differentiation‐induced changes of lytic sensitivity (1984) (6)
A unique variant of ETV6/AML1 fusion in a child with acute lymphoblastic leukemia (2003) (6)
Genetic and genomic analysis of acute lymphoblastic leukemia in older adults reveals a distinct profile of abnormalities: analysis of 210 patients from the UKALL14 and UKALL60+ clinical trials (2021) (6)
Prognostic Impact of Chromosomal Abnormalities and Copy Number Alterations Among Adults with B-Cell Precursor Acute Lymphoblastic Leukaemia Treated on UKALL14 (2019) (6)
Genetic characterisation of childhood B‐other‐acute lymphoblastic leukaemia in UK patients by fluorescence in situ hybridisation and Multiplex Ligation‐dependent Probe Amplification (2021) (6)
New genetics and diagnosis of childhood B-cell precursor acute lymphoblastic leukemia (2011) (6)
Investigation of human chromosome polymorphisms by scanning electron microscopy. (1985) (6)
Clinical relevance of failed and missing cytogenetic analysis in acute myeloid leukaemia (2017) (5)
Cytogenetics of long‐term survivors of ETV6‐RUNX1 fusion positive acute lymphoblastic leukemia (2009) (5)
SSBP2-CSF1R is a Recurrent Fusion in B-lineage Acute Lymphoblastic Leukaemia with Diverse Genetic Presentation and Variable Outcome. (2020) (5)
10. Acute lymphoblastic leukemia (2015) (5)
Refinement of cytogenetic classification in AML: determination of prognostic significance of rare recurring chromosomal abnormalities amongst patients entered into the UK MRC AML 10 & 12 trials. (2002) (5)
DOWN'S Syndrome Acute Lymphoblastic LEUKEMIA: A HIGHLY Heterogeneous DISEASE DRIVEN by an Aberrant CRLF2/JAK2 Cooperation – A REPORT FROM the Ibfm-STUDY GROUP. (2009) (5)
RUXOLITINIB COMPARED WITH BEST AVAILABLE THERAPY FOR ESSENTIAL THROMBOCYTHAEMIA PATIENTS RESISTANT OR INTOLERANT TO HYDROXYCARBAMIDE IN MAJIC - AN INVESTIGATOR LEAD RANDOMIZED TRIAL (2016) (5)
SSBP2-CSF1R Is a Recurrent Fusion in B-Other Acute Lymphoblastic Leukaemia with Variable Clinical Outcome (2014) (5)
IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia (2019) (5)
The Frequency and Outcome of Ph-like ALL Associated Abnormalities in Childhood Acute Lymphoblastic Leukaemia Treated on MRC UKALL2003 (2016) (4)
Clinical impact of additional cytogenetic aberrations, cKIT- and RAS mutations and other factors in pediatric t(8;21)-AML (2014) (4)
AN INTERSTITIAL DELETION IN THE REARRANGED T‐CELL RECEPTOR γCHAIN LOCUS IN A CASE OF T‐CELL ACUTE LYMPHOBLASTIC LEUKAEMIA (1995) (4)
Cytogenetics of childhood AML from UK medical research council treatment trials, AML10 & 12. (2003) (4)
Cytogenetics and Molecular Genetics (2017) (4)
Haploinsufficiency of the MLL and TOB2 genes in lymphoid malignancy (2010) (4)
Molecular Characterization of AML1 (RUNX1) Amplification: A Poor Risk Chromosomal Marker in Acute Lymphoblastic Leukaemia (ALL). (2004) (4)
Del(9q) AML: Clinical, cytological and cytogenetic characteristics and prognostic implications for patients entering the MRC AML trials. (1999) (4)
HYPERFIBROTIC MYELODYSPLASIA (1991) (4)
Molecular cytogenetics in childhood leukemia. (2004) (4)
MYB rearrangements and over‐expression in T‐cell acute lymphoblastic leukemia (2021) (4)
The 9 p 21 . 3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN 2 A (2015) (4)
Extended Data Table 1 (2014) (4)
Time to Cure for Childhood and Young Adult Acute Lymphoblastic Leukemia Is Independent of Early Risk Factors: Long-Term Follow-Up of the UKALL2003 Trial (2022) (4)
Genomic analysis drives tailored therapy in poor risk childhood leukemia. (2012) (4)
leukemia lymphoid transformation in B-cell precursor acute lymphoblastic , is involved in CRLF2 Deregulated expression of cytokine receptor gene, (2011) (4)
The lymphomas and chronic lymphoproliferative disorders (2000) (4)
Fluorescence In situ hybridization (FISH) as a tool for the detection of significant chromosomal abnormalities in childhood leukaemia. (2009) (4)
hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia (2022) (4)
Acute Lymphoblastic Leukemia with Zinc-Finger Protein 384 (ZNF384)-Related Rearrangements: A Retrospective Analysis from the Ponte Di Legno Childhood ALL Working Group (2019) (4)
Prognostic significance of chromosomal abnormalities at relapse in children with relapsed acute myeloid leukemia: A retrospective cohort study of the Relapsed AML 2001/01 Study (2021) (4)
Whole genome sequencing provides comprehensive genetic testing in childhood B-cell acute lymphoblastic leukaemia (2023) (3)
Cancer Cytogenetics: Chromosomal and Molecular Genetic Aberrations of Tumour Cells, 2nd edn (1997) (3)
Involvement of the CEBP Gene Family in Four IGH@ Chromosomal Translocations in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL). (2005) (3)
The Spectrum and Prognostic Relevance of Additional Abnormalities, Involving 12p and 21q, in Children with ETV6 - RUNX1 Positive Acute Lymphoblastic Leukaemia (ALL) (2008) (3)
NUTM1-Rearranged Infant and Pediatric B Cell Precursor Acute Lymphoblastic Leukemia: A Good Prognostic Subtype Identified in a Collaborative International Study (2020) (3)
Gender Differences and MPN Symptom Burden : An Analysis by the MPN Quality of Life International Study Group (MPN-QOL ISG) (2014) (3)
Composite Index for Risk Prediction in Relapsed Childhood Acute Lymphoblastic Leukaemia (2015) (3)
Monosomy 7 and Deletion 7q in Childhood AML. A Collaborative Study of 20 Study Groups. (2004) (3)
Chromosomal evidence of a common stem cell in acute lymphoblastic leukemia and chronic granulocytic leukemia. (1984) (3)
Oligoclonality: an insight into the biology of acute lymphoblastic leukaemia (2001) (2)
Multiple Myeloma with IGH-Involving del(14q): Report of 34 Cases. (2007) (2)
A non-melanic variant bullfinch (1969) (2)
EBF1-PDGFRΒ Fusion in Paediatric Acute Lymphoblastic Leukaemia (ALL): Genetic Profile and Clinical Implications (2014) (2)
Impact of Chromosomal Abnormalities Revealed by Interphase FISH on Survival in Primary Light Chain Amyloidosis. (2004) (2)
Identification of novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia (2009) (2)
Detection of genomic aberrations in older patients with acute myeloid leukemia. (2005) (2)
Clinical Impact of Additional Cytogenetic Aberrations and Complex Karyotype In Pediatric 11q23/ MLL -Rearranged AML: Results from an International Retrospective Study (2010) (2)
Prevention of childhood leukaemia by lifestyle changes (2021) (2)
Correction: The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL (2019) (2)
Acute monocytic leukaemia and t(2;6) (p21;q26) translocation. (1989) (2)
PERSIST-1: A PHASE III STUDY OF PACRITINIB (PAC) VS BEST AVAILABLE THERAPY (BAT) IN PRIMARY MYELOFIBROSIS (PMF), POST-POLYCYTHEMIA VERA MF (PPV-MF) OR POST-ESSENTIAL THROMBOCYTHEMIA MF (PET-MF) (2015) (2)
Improved Treatment of Childhood ALL in Malaysia (2019) (2)
Intragenic ampli fi cation of PAX 5 : a novel subgroup in B-cell precursor acute lymphoblastic leukemia ? (2017) (2)
The clinical characteristics , therapy and outcome of 85 adults with acute lymphoblastic leukemia and t ( 4 ; 11 ) ( q 21 ; q 23 ) / MLL-AFF 1 prospectively treated on UKALLXII / ECOG (2013) (2)
Outcomes of Childhood Noninfant Acute Lymphoblastic Leukemia With 11q23/KMT2A Rearrangements in a Modern Therapy Era: A Retrospective International Study (2022) (2)
Translocation t(6;9)(p22;q34)/DEK-NUP214 rearranged Pediatric AML: A Retrospective International Study (2012) (1)
Cytogenetic and genomic characterization of cell line ARH77. (2008) (1)
Genetic and Genomic Characterisation of Older Adults with Acute Lymphoblastic Leukemia Treated on the UKALL14 and UKALL60+ Clinical Trials (2019) (1)
Immunoglobulin Heavy Chain Locus (IGH@) Translocations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Incidence and Risk Stratification (2012) (1)
Clinical Impact of Additional Cytogenetic Aberrations and Treatment in Pediatric t(8;21)-Positive AML: Results from an International Retrospective I-BFM-SG Study (2012) (1)
The presence of the factor V Leiden and the prothrombin G20210A polymorphism does not appear to influence the risk of thrombosis in essential thrombocythaernia: results of a nested case control study (2008) (1)
Epigenetic Regulator Genes Direct the Fate of Multipotent Progenitor Cell of Origin in Lineage Switched MLL-AF4 Leukaemia (2019) (1)
Identification of Cmtm Family Proteins As Tumor Suppressor and Membrane Regulator in B Cell Precursor Acute Lymphoblastic Leukemia (2014) (1)
Rate Of Malignant Transformation In High Risk Et During 5 Years Of Follow-Up Of Cytoreductive Therapy (2016) (1)
Impact Of Splenomegaly On Mpn Symptoms And Association With Clinical Features : An Analysis By The Mpn Quality Of Life International Study Group (2016) (1)
Treatment Intensification Improves Outcome in Children with iAMP21 positive ALL (2012) (1)
Changes in surface morphology associated with ageing and carcinogen treatment of Chinese hamster lung cells. (1980) (1)
Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia (2015) (1)
5. Acute Myeloid Leukemia (2010) (1)
Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high‐hyperdiploid B‐cell acute lymphoblastic leukemia (2022) (1)
407: Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia (2014) (1)
Improved Diagnosis of Intrachromosomal Amplification of Chromosome 21 (iAMP21) By Copy Number Profiling (2016) (1)
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2018) (1)
Genome complexity in patients with B-lineage acute lymphoblastic leukaemia revealed by array-based comparative genomic hybridization (2007) (1)
Advances in Molecular Cytogenetics to Study the Leukemia Genome (2007) (1)
Diagnostic utility of whole genome sequencing in adults with B-other acute lymphoblastic leukemia. (2022) (1)
The role of clinical cytogenetics in medicine: with special emphasis on oncology. (1988) (1)
Translocations Co-exist With Other Primary Rearrangements in B-cell Precursor Acute Lymphoblastic Leukemia (1)
Characterization of unusual iAMP21 B‐lymphoblastic leukemia (iAMP21‐ALL) from the Mayo Clinic and Children's Oncology Group (2022) (1)
Cytogenetics of Leukaemia and Lymphoma (2007) (1)
Disruption to the FOXO-PRDM1 axis resulting from deletions of chromosome 6 in acute lymphoblastic leukaemia (2023) (1)
subgroups loss of heterozygosity, and association with specific cytogenetic lymphoblastic leukemia reveals genomic deletion, copy number neutral gene in childhood acute CDKN2A A comprehensive analysis of the (2009) (1)
RISK FACTORS FOR THROMBOHEMORRHAGIC AND TRANSFORMATION EVENTS IN 3649 HIGH-RISK PATIENTS WITH ESSENTIAL THROMBOCYTHEMIA : RESULTS FROM THE PROSPECTIVE LONG-TERM OBSERVATIONAL EXELS STUDY (2015) (1)
Karyotyping lymph node biopsies in non-Hodgkin's lymphoma. (2005) (1)
Single Nucleotide Polymorphism Array-Based Signature of Genetic Ploidy Groups in Acute Lymphoblastic Leukemia (2019) (1)
Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement (2022) (1)
Long Term Overall Survival of Greater Than 98% in Childhood ALL Patients with Good Risk Features and Low Risk MRD: (A)over-cap Results from a Large Multi-Center Randomized Controlled Trial, UKALL 2003 (2015) (1)
The Prognostic Impact of Cytogenetics and Karyotype Changes in Pediatric Patients with Relapsed Acute Myeloid Leukemia: A Retrospective Cohort Study within the Relapsed AML 2001/01 Study (2016) (1)
Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia (2021) (1)
HGNC nomenclature for fusion genes (2021) (1)
Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG (2020) (1)
The Clinical Relevance Of Genetics In Predicting Outcome After a First Relapse In Children With B-Cell Precursor Acute Lymphoblastic Leukaemia (2013) (1)
Palpitations And Arrhythmia In 3649 High-Risk Patients With Essential Thrombocythemia : Results From The Prospective Long-Term Observational Exels Study (2016) (1)
Ikzf1 Deletion Status Discriminates For Outcome In Imatinibtreated Bcr-Abl1-Positive Childhood ALL (2013) (1)
OUTCOMES FOR MYELOFIBROSIS PATIENTS WHO SWITCHED FROM FEDRATINIB TO RUXOLITINIB THERAPY (2014) (1)
Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia (2020) (1)
297 THE HEPATIC PROGENITOR B-13 CELL LINE ENGRAFTS INTO THE MOUSE LIVER AND TRANSDIFFERENTIATES IN VIVO (2013) (1)
IGH@ Translocations Involving the Pseudoautosomal Region 1 (PAR1) of Both Sex Chromosomes Deregulate the Cytokine Receptor-Like Factor 2 (CRLF2) Gene in B Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) (2008) (1)
Advances in acute lymphoblastic leukemia genomics (2018) (1)
Genome Complexity in Patients with Acute Lymphoblastic Leukaemia Revealed by Array-Based Comparative Genomic Hybridization. (2006) (1)
Integrative genomic analysis of childhood acute lymphoblastic leukaemia lacking a genetic biomarker in the UKALL2003 clinical trial (2022) (1)
Molecular versus flow cytometric MRD analysis - is there an explanation for discrepancies? (2012) (0)
Ruxolitinib induces changes in histone modification status in patients entered into the MAJIC clinical trial (2018) (0)
The exels study : Real-world cytoreductive treatment patterns for essential thrombocythaemia in Europe (analysis of 3643 patients) (2013) (0)
Clinical Relevance of Genes Commonly Deleted in Childhood B-Cell Precursor ALL (BCP-ALL) (2012) (0)
Multiple novel genes are deregulated by IGH@ in B cell precursor acute lymphoblastic leukaemia including five members of the CEBP gene family (2007) (0)
Oncogenomic Screening Strategies to Identify Tumour Suppressor Genes on Chromosome 12 in Acute Myeloid Leukaemia (2014) (0)
PB2212 FACING ERYTHROCYTOSIS: RESULTS OF AN INTERNATIONAL PHYSICIANS’ SURVEY (2019) (0)
Biallelic Inactivation of TP53 is Associated with an Increased Risk of Relapse in Paediatric B-Cell Non-Hodgkin Lymphoma(B-NHL) (2019) (0)
Development of an MF patient reported outcome (PRO) tool for FDA qualification: Comprehensive literature search and physician cognitive debriefing results (2016) (0)
Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2019) (0)
Short communication A diminutive chromosome 21 centromere in acute lymphoblastic leukemia (2006) (0)
Fluorescence in Situ Hybridisation (FISH) Detection of Prognostically Relevant Chromosomal Abnormalities in Childhood Acute Myeloid Leukaemia (AML) (2016) (0)
Feasibility of recruitment of patients with Myeloproliferative Neoplasms into the TAP funded TAMARIN study (2018) (0)
CMYC-translocations in t-cell acute lymphoblastic leukemia (2014) (0)
myeloid leukemia: results of an international retrospective study Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute (2013) (0)
Critical Importance of Conventional Cytogenetics in Detecting Prognostically Significant Chromosome 13 Deletions in Myeloma. (2005) (0)
Five CCAAT-enhancer-binding-protein gene family members are deregulated by the immunoglobulin heavy chain locus in B-cell precursor acute lymphoblastic leukaemia (2007) (0)
Leukemia Cells with a BCR-ABL1-Like signature and/or IKZF1 deletions, but Not High CRLF2 Expression, Are Predictive of an Unfavorable Prognosis in Childhood B Cell Precursor Acute Lymphoblastic Leukemia (2012) (0)
ALL expression, in children with B-cell precursor CRLF2 deletion, but not high IKZF1 signature and BCR-ABL1-like Independent prognostic value of (2013) (0)
Age specific incidence of partner gene and secondary abnormalities in MLL positive acute lymphoblastic leukaemia (ALL) (2015) (0)
Integration Of Cytogenetic and Copy Number Alteration (CNA) Data Into a Single Risk Profile For Paediatric Acute Lymphoblastic Leukaemia (ALL) (2013) (0)
A6) Aplastic anaemia (AA) or hypoplastic MDS (1991) (0)
BACH2 and BCL6 Cooperatively Fuction as Tumour Suppressors in CLL (2016) (0)
Delineation of Risk Factors in Paediatric Acute Lymphoblastic Leukaemia with Favourable Cytogenetics (2012) (0)
Cytogenetic classification of T lineage acute lymphoblastic leukaemia: multiple partners of BCL11B and other novel rearrangements (2006) (0)
Genes Commonly Deleted in Childhood B-Cell Precursor ALL (BCP-ALL) Are Associated with Major Cytogenetic Subgroups (2012) (0)
PAX5-ETV6 fusion in acute lymphoblastic leukaemia does not define the dic(9;12) (2006) (0)
Lineage switching in MLL-AF 4 leukaemias 1 Epigenetic regulator genes direct lineage switching in MLL-AF 4 leukaemia 1 (2021) (0)
IKZF 1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia (2019) (0)
Quantitative Proteomic Analysis Reveals Maturation As a Mechanism Underlying Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia and PAX5 As a Re-Sensitising Therapeutic Target (2011) (0)
Disruption of PAX5 in patients with acute lymphoblastic leukaemia and dicentric chromosomes (2007) (0)
P343: GENOMIC CHARACTERISATION OF B-OTHER ALL IN UKALL2003 PATIENTS BY NEXT GENERATION SEQUENCING (2022) (0)
Analysis of MLL Translocations in Acute Leukemia. MLLFC-AACR-2004 (2014) (0)
pediatric patients with Down syndrome: an iBFM-SG study Cytogenetic features of acute lymphoblastic and myeloid leukemias in (2013) (0)
Clonal Evolution and Sub-Clonal Architecture In Paediatric T-Cell Acute Lymphoblastic Leukaemia (T-ALL) (2013) (0)
Integrating Genetic Risk Factors with Age, Presenting White Cell Count and MRD Response As Continuous Variables to Predict Relapse in Paediatric Acute Lymphoblastic Leukemia (ALL) (2016) (0)
Five C/EPB gene family members are deregulated by IGH@ in B-cell precursor acute lymphoblastic leukemia. (2006) (0)
IDENTIFICATION OF MULTIPLE NOVEL IGH@ TRANSLOCATIONS IN ADOLESCENT ACUTE LYMPHOBLASTIC LEUKAEMIA. (2008) (0)
childhood B-cell precursor acute lymphoblastic leukemia (2016) (0)
Abstract A43: Genetic and epigenetic disorders in one cohort of acute lymphoblastic leukemia (2018) (0)
Megakaryocytes from chronic myeloproliferative disorders show enhanced nuclear bFGF expression (2002) (0)
Down syndrome acute lymphoblastic leukemia R 683 ) and multiple gene deletions in JAK 2 mutation ( JAK 2 Specific (2009) (0)
Genomic landscape of adult and paediatric B-cell Non-Hodgkin lymphoma (2018) (0)
PS921 INACTIVATION OF SH2B3 THROUGH CN-LOH 12Q IS UNIQUELY ASSOCIATED WITH B-CELL PRECURSOR ALL WITH IAMP21 OR OTHER CHROMOSOME 21 GAIN (2019) (0)
A Targeted Functional Clone Tracking Assay for the Identification of Tumour Suppressor Genes in BCP- ALL Implicates the Transcription Factors FOXO3 and PRDM1 (2015) (0)
Clinical characteristics and outcomes of B-cell precursor ALL with MEF2D rearrangements: a retrospective study by the Ponte di Legno Childhood ALL Working Group (2022) (0)
Balanced Rearrangements of Chromosome 6 in Acute Leukaemia: Clustered Breakpoints in 6q22-q23 and Possible Involvement of c-MYB/AHI1 in a New Recurrent Translocation, t(6;7)(q23;q31). (2004) (0)
A Breakage-Fusion-Bridge Cycle Generated by Telomeric Loss May Underlie the dup(21q) of Acute Lymphoblastic Leukemia. (2005) (0)
A comparative map of 6q deletions in ALL: Identification and analysis of GluR-6 as a candidate tumour suppressor gene (2003) (0)
Genotype-Speci fi c Minimal Residual Disease Interpretation Improves Strati fi cation in Pediatric Acute Lymphoblastic Leukemia (2017) (0)
O21: Amplification and instability of chromosome 21 in patients with ALL identified with BAC and oligonucleotide-based array CGH (aCGH) (2005) (0)
Treatment Outcomes of Childhood Picalm:MLLT10+ Acute Leukemias: An International Retrospective Study (2022) (0)
Modeling the molecular consequences of unbalanced translocation in cancer; lessons from leukemia (2009) (0)
Multi-center performance evaluation of a biochip designed to analyze the expression of 11q23/MLL abnormal fusion transcripts in acute leukemia (2004) (0)
Ras Signalling Pathway and Novel Target Genes Related to Down Syndrome Contribute to the Development of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in iAMP21 Patients (2011) (0)
Brief LYMPHOID NEOPLASIA EBF1-PDGFRB fusion in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): genetic pro ﬁ le and clinical implications (2016) (0)
The Sub-Clonal Complexity of STIL-TAL1 T-ALL (2014) (0)
ALL positive childhood - BCR-ABL1 status as a prognostic feature in IKZF1 (2014) (0)
A Genome-Wide CRISPR Screen Implicates MYC Dysregulation in TCF3-PBX1 B-ALL (2018) (0)
Digital Multiplex Ligation-Dependent Probe Ampli fi cation for Detection of Key Copy Number (2017) (0)
mutated JAK2: a report from the International BFM Study Group disease in which aberrant expression of CRLF2 is associated with Down syndrome acute lymphoblastic leukemia, a highly heterogeneous (2013) (0)
Treatment Of Essential Thrombocythemia In Europe : Observational Study Of 3649 Patients Of High Risk (Exels) (2015) (0)
Integration of Minimal Residual Disease with Other Patient Risk Factors Identifies a Population with Very Poor Overall Survival in Pediatric ALL: Results from the UKALL 2003 Trial (2015) (0)
stratification in pediatric acute lymphoblastic leukemia A novel integrated cytogenetic and genomic classification refines risk (2014) (0)
Somatic mutations are important factors in tumorigenesis (2011) (0)
LYMPHOID NEOPLASIA IKZF 1 status as a prognostic feature in BCR-ABL 1 – positive childhood ALL (2014) (0)
Residual Ph− cells in chronic myeloid leukemia: Detection and usefulness (1993) (0)
Novel prognostics subgroups in childhood 11Q23/MLL-rearranged acute myeloid leukemia as defined by translocation partners: A retrospective international study (2009) (0)
585 Analytical and multi-center clinical performance evaluation of a diagnostic device designed to analyze the expression of 11q23/MLL abnormal fusion transcripts in acute leukemia (2004) (0)
Measurable Residual Disease and Fusion Partner Independently Predict Survival and Relapse Risk in Childhood KMT2A-Rearranged Acute Myeloid Leukemia: A Study by the International Berlin-Frankfurt-Münster Study Group. (2023) (0)
Reply to the letter of Joenje et al. titled “confounding factors in the diagnosis of Fanconi anaemia.” (1998) (0)
Short communication Is trisomy 5 a distinct cytogenetic subgroup in acute lymphoblastic leukemia (2004) (0)
international study -rearranged AML patients: results of an MLL novo pediatric 11q23/ Prognostic significance of additional cytogenetic aberrations in 733 de (2011) (0)
Genetic Characterisation of Immunoglobulin Heavy Chain Locus CCAAT Enhancer-Binding Protein Translocated Acute Lymphoblastic Leukaemia (2015) (0)
Cytogenetic-Specific Heterogeneity in the Kinetics of Minimal Residual Disease (MRD) Clearance in Childhood Acute Lymphoblastic Leukaemia (ALL). (2007) (0)
Molecular MRD Monitoring Is Feasible in the Majority of Children with AML and Is Highly Predictive of Outcome: Results from the International MyeChild01 Study (2019) (0)
MLPA and DNA index improve the molecular diagnosis of childhood B-cell acute lymphoblastic leukemia (2020) (0)
TP53 STATUS RISK STRATIFIES PATIENTS WITH CLINICALLY DEFINED HIGH-RISK DISEASE PAEDIATRIC B-CELL NON-HODGKIN LYMPHOMA (2022) (0)
Assessment of aneuploidy in childhood acute lymphoblastic leukaemia using high density oligonucleotide arrays. (2006) (0)
Risk Factor Analysis in Paediatric Acute Lymphoblastic Leukaemia with High Hyperdiploidy (2015) (0)
Intrachromosomal Amplification of Chromosome 21(iAMP21): Cytogenetic Characterisation and Outcome in Childhood B-Cell Precursor Acute Lymphoblastic Leukaemia (BCP-ALL). A Study On Behalf of the Ponte Di Legno International Childhood ALL Workshop (2012) (0)
Poster session. Multiple myeloma with IGH-involving del(14q): Report of 34 cases (2007) (0)
Heterogeneous breakpoints target PAX5 in acute lymphoblastic leukaemia patients with dicentric chromosomes (2008) (0)
event in childhood B-cell precursor acute lymphoblastic leukemia Genomic characterization implicates iAMP21 as a likely primary genetic (2011) (0)
A human iPSC derived bone marrow milieu identifies a novel target against niche-conferred leukaemia proliferation and treatment resistance (2021) (0)
Invited Lectures (2009) (0)
Molecular Diagnostics for Haematological Cancer (2006) (0)
Genomic profiling reveals multiple genetic targets in ETV6-RUNX1 positive acute lymphoblastic leukaemia (ALL) (2007) (0)
Genomic and expression profiling defines the molecular features of intrachromosomal amplification of chromosome 21 in acute lymphoblastic leukemia (2007) (0)
Diagnostic Techniques in Hematological Malignancies: Cytogenetics (2010) (0)
Comprehensive analysis of p16(INK4a) in childhood acute lymphoblastic leukemia reveals homozygous deletion, haploinsufficiency and acquired isodisomy at the 9p locus with intact p16(INK4a). (2006) (0)
Biallelic inactivation of TP53 is associated with an increased risk of relapse in paediatric B-cell non-Hodgkin lymphoma (B-NHL) (2018) (0)
Prognostic Relevance of Cytogenetics in Childhood Acute Lymphoblastic Leukaemia (ALL): Final Results From MRC ALL97. (2009) (0)
A de novo (1;2;3;15;18) chromosome rearrangement with six nonreciprocal translocations. (2007) (0)
Mutation in genes impacting on the RAS-RAF-MEK-ERK pathway are found at high incidence in childhood acute lymphoblastic leukemia at both diagnosis and at relapse. (2006) (0)
1 Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome – an iBFM-SG study OF ACUTE LEUKEMIA IN DOWN SYNDROME (2007) (0)
What Is the Initiating Mechanism of iAMP21 in Childhood B Cell Precursor ALL (2009) (0)
leukemia (BCP-ALL) translocations in B-cell precursor acute lymphoblastic IGH recurrent transcription factor family are targeted by CEBP Five members of the (2011) (0)
Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (2019) (0)
Advances in the Genetics of Childhood Leukaemia: a Success Story (2015) (0)
A diminutive chromosome 21 centromere in acute lymphoblastic leukemia. (2006) (0)
Extended Data Legend (2014) (0)
ISCN (2009): Important revisions and new additions to molecular methods for copy number detection for cytogenetic analysis (2009) (0)
Stable asymptomatic myeloma and MGUS in the presence of T(4;14) (2007) (0)
Abstract B21: Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia (2016) (0)
Cytogenetic classification of T lineage acute lymphoblastic leukaemia (2007) (0)
Refinement of IKZF1 Genomic Status in Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia (2014) (0)
Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia (2016) (0)
Inactivation of CDKN2A in childhood acute lymphoblastic leukaemia (ALL) occurs principally by deletion and is strongly correlated with cytogenetic subgroups (2007) (0)
A GENOMEWIDE ASSOCIATION STUDY IDENTIFIES NOVEL LOCI THAT PREDISPOSE TO MYELOPROLIFERATIVE NEOPLASMS (2013) (0)
Targeted resequencing of 115 genes identifies association between jak3 and epigenetic mutations in t-cell acute lymphoblastic leukemia (2014) (0)
Prognostic Significance and Risk Stratification in Acute Myeloid Leukaemia Patients in the Absence of Successful Cytogenetic Analysis (2015) (0)
Red blood cell alloimmunization is affected by depletion of donor white cell subsets (2007) (0)
dup ( 21 q ) amplified ( RUNX 1 ) (2011) (0)
Fe ZF 1 Deletions with COBL reakpoints Are Not Driven by AG-Mediated Recombination vents in Acute Lymphoblastic eukemia (2020) (0)
loss of heterozygosity and association with specific cytogenetic subgroups lymphoblastic leukaemia reveals genomic deletion , copy number neutral gene in childhood acute CDKN 2 (2008) (0)
GENETIC VARIATION AT HBS1L-MYB AND GFI1B-GTF3C5 INFLUENCES WHETHER JAK2 V617F MUTATED MPN PRESENT WITH ET OR PV (2016) (0)
A Novel Multiplex NGS-Based Digital MLPA Assay for Copy Number Detection of 700 Target Sequences in Childhood Acute Lymphoblastic Leukemia (2016) (0)
A single centre experience of mastocytosis: Guy's and St Thomas' NHS Foundation Trust (2008) (0)
Hypereosinophilic syndrome: challenges in diagnosis and management (2007) (0)
Clonal Progression Including Evolution Of An iAMP21 Chromosome In Xenograft Models Of BCP-ALL (2013) (0)
Whole Genome Sequencing for Detection of Prognostically Relevant Genetic Abnormalities in Paediatric Acute Myeloid Leukaemia (2022) (0)

This paper list is powered by the following services:

Other Resources About Christine Harrison

en.wikipedia.org

What Schools Are Affiliated With Christine Harrison?

Christine Harrison is affiliated with the following schools: