Christine L. Mummery
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Dutch university teacher
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Christine L. Mummery's Degrees
- PhD Biology Leiden University
- Masters Biology Leiden University
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Why Is Christine L. Mummery Influential?
(Suggest an Edit or Addition)According to Wikipedia, Christine L. Mummery is an appointed professor of Developmental Biology at Leiden University and the head of the Department of Anatomy and Embryology at Leiden University Medical Center in the Netherlands.
Christine L. Mummery's Published Works
Published Works
- A promoter-level mammalian expression atlas (2014) (1664)
- Characterization of human embryonic stem cell lines by the International Stem Cell Initiative (2007) (1041)
- MicroRNAs in the Human Heart: A Clue to Fetal Gene Reprogramming in Heart Failure (2007) (954)
- Differentiation of Human Embryonic Stem Cells to Cardiomyocytes: Role of Coculture With Visceral Endoderm-Like Cells (2003) (870)
- Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling. (2003) (713)
- Endoglin promotes endothelial cell proliferation and TGF‐β/ALK1 signal transduction (2004) (648)
- Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview. (2012) (603)
- Stem-cell-based therapy and lessons from the heart (2008) (544)
- Abnormal angiogenesis but intact hematopoietic potential in TGF‐β type I receptor‐deficient mice (2001) (543)
- Autotaxin, a Secreted Lysophospholipase D, Is Essential for Blood Vessel Formation during Development (2006) (532)
- Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells (2015) (502)
- Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin (2004) (497)
- Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage (2011) (489)
- Recombinant Vitronectin Is a Functionally Defined Substrate That Supports Human Embryonic Stem Cell Self‐Renewal via αVβ5 Integrin (2008) (422)
- Induced pluripotent stem cells: the new patient? (2012) (422)
- NKX2-5eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes (2011) (416)
- Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction. (2007) (401)
- Functional analysis of the TGFbeta receptor/Smad pathway through gene ablation in mice. (2000) (386)
- Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes. (2010) (376)
- Increased Cardiomyocyte Differentiation from Human Embryonic Stem Cells in Serum‐Free Cultures (2005) (348)
- Organs-on-chips: into the next decade (2020) (326)
- Phosphorylation dynamics during early differentiation of human embryonic stem cells. (2009) (325)
- Cardiomyocyte differentiation of mouse and human embryonic stem cells * (2002) (316)
- Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia (2010) (300)
- Human embryonic stem cells: research, ethics and policy. (2003) (292)
- Adult Neurogenesis Requires Smad4-Mediated Bone Morphogenic Protein Signaling in Stem Cells (2008) (275)
- Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology (2015) (270)
- Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK. (2008) (263)
- Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells (2014) (253)
- Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents. (2008) (251)
- Cardiomyocytes Derived From Pluripotent Stem Cells Recapitulate Electrophysiological Characteristics of an Overlap Syndrome of Cardiac Sodium Channel Disease (2012) (251)
- Small molecule absorption by PDMS in the context of drug response bioassays (2017) (250)
- Isl1Cre reveals a common Bmp pathway in heart and limb development (2006) (243)
- TGF-beta1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro. (2008) (240)
- Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease (2020) (238)
- Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem? (2015) (229)
- BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. (2004) (212)
- Rapid ionic events and the initiation of growth in serum-stimulated neuroblastoma cells (1981) (211)
- Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells (2017) (210)
- Origins and Fates of Cardiovascular Progenitor Cells (2008) (206)
- Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades. (2012) (203)
- Molecular cloning, genetic mapping, and developmental expression of bovine POU5F1. (1999) (200)
- Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure. (2016) (195)
- Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cells. (2008) (195)
- Induced pluripotent stem cell derived cardiomyocytes as models for cardiac arrhythmias (2012) (191)
- Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro--correlation between contraction force and electrophysiology. (2015) (183)
- Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome (2013) (178)
- RNA and protein localisations of TGF beta 2 in the early mouse embryo suggest an involvement in cardiac development. (1993) (175)
- The human adult cardiomyocyte phenotype. (2003) (175)
- Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells (2015) (173)
- Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome. (2007) (172)
- Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium. (2009) (171)
- Resistance to transforming growth factor beta and activin due to reduced receptor expression in human breast tumor cell lines. (1995) (166)
- Functionality of Endothelial Cells and Pericytes From Human Pluripotent Stem Cells Demonstrated in Cultured Vascular Plexus and Zebrafish Xenografts (2014) (164)
- Defective paracrine signalling by TGFβ in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia (2004) (163)
- Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: Disease mechanisms and pharmacological rescue (2014) (157)
- Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function (2015) (155)
- FANTOM5 CAGE profiles of human and mouse samples (2017) (153)
- Origin and use of embryonic and adult stem cells in differentiation and tissue repair. (2003) (151)
- Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells (2015) (139)
- Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device. (2013) (139)
- Personalised organs-on-chips: functional testing for precision medicine (2018) (138)
- An experimental correction for arginine-to-proline conversion artifacts in SILAC-based quantitative proteomics (2007) (137)
- Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A (2011) (135)
- Endoglin Has a Crucial Role in Blood Cell–Mediated Vascular Repair (2006) (132)
- MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo (2017) (131)
- Insulin Redirects Differentiation from Cardiogenic Mesoderm and Endoderm to Neuroectoderm in Differentiating Human Embryonic Stem Cells (2008) (131)
- Expression of TGF-beta s and their receptors during implantation and organogenesis of the mouse embryo. (1994) (130)
- Expression of ALK‐1, a type 1 serine/threonine kinase receptor, coincides with sites of vasculogenesis and angiogenesis in early mouse development (1997) (130)
- A Quest for Human and Mouse Embryonic Stem Cell-specific Proteins *S (2006) (128)
- Compensatory signalling induced in the yolk sac vasculature by deletion of TGFβ receptors in mice (2007) (124)
- Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis (1995) (120)
- Genome-wide transcriptional profiling of human embryonic stem cells differentiating to cardiomyocytes. (2006) (120)
- Transforming growth factor-beta signalling in extraembryonic mesoderm is required for yolk sac vasculogenesis in mice. (1999) (119)
- Hereditary hemorrhagic telangiectasia: an update on transforming growth factor beta signaling in vasculogenesis and angiogenesis. (2003) (118)
- Influence of FSH and hCG on the resumption of meiosis of bovine oocytes surrounded by cumulus cells connected to membrana granulosa (1996) (118)
- Consensus Guidance for Banking and Supply of Human Embryonic Stem Cell Lines for Research Purposes (2009) (117)
- Differentiation is coupled to changes in the cell cycle regulatory apparatus of human embryonic stem cells. (2007) (116)
- Plasma membrane proteomics of human embryonic stem cells and human embryonal carcinoma cells. (2008) (115)
- Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development. (2011) (114)
- Complex Tissue and Disease Modeling using hiPSCs. (2016) (114)
- Myocardial tissue engineering: in vitro models. (2014) (113)
- Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development. (1998) (112)
- Conversion of Mature Human β-Cells Into Glucagon-Producing α-Cells (2013) (112)
- Visceral-endoderm-like cell lines induce differentiation of murine P19 embryonal carcinoma cells. (1991) (111)
- Characteristics of embryonic stem cell differentiation: a comparison with two embryonal carcinoma cell lines. (1990) (111)
- Challenges in Using Stem Cells for Cardiac Repair (2010) (109)
- Improved genetic manipulation of human embryonic stem cells (2008) (108)
- Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come? (2016) (108)
- Cation transport and growth regulation in neuroblastoma cells. Modulations of K+ transport and electrical membrane properties during the cell cycle (1981) (107)
- Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI). (2015) (106)
- Transplantation of cells for cardiac repair. (2003) (104)
- Clonal variants of differentiated P19 embryonal carcinoma cells exhibit epidermal growth factor receptor kinase activity. (1985) (103)
- Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction (2004) (101)
- Comprehensive Microarray Analysis of Bone Morphogenetic Protein 2‐Induced Osteoblast Differentiation Resulting in the Identification of Novel Markers for Bone Development (2002) (101)
- KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas (2015) (100)
- Identification of cell surface proteins for antibody-based selection of human embryonic stem cell-derived cardiomyocytes. (2010) (99)
- The ISSCR Guidelines for Human Embryonic Stem Cell Research (2007) (99)
- Variants of the alpha 6 beta 1 laminin receptor in early murine development: distribution, molecular cloning and chromosomal localization of the mouse integrin alpha 6 subunit. (1993) (98)
- Microarray analysis reveals expression regulation of Wnt antagonists in differentiating osteoblasts. (2005) (97)
- Gene-specific vulnerability to imprinting variability in human embryonic stem cell lines. (2007) (97)
- Identification of Novel Regulators Associated With Early‐Phase Osteoblast Differentiation (2004) (97)
- Cardiomyocytes from human pluripotent stem cells in regenerative medicine and drug discovery. (2009) (97)
- Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology. (2019) (95)
- Establishment of a differentiated mesodermal line from P19 EC cells expressing functional PDGF and EGF receptors. (1986) (93)
- Spatio-temporal activation of Smad1 and Smad5 in vivo: monitoring transcriptional activity of Smad proteins (2004) (93)
- Genome‐Wide Transcriptional Profiling of Human Embryonic Stem Cells Differentiating to Cardiomyocytes (2006) (92)
- Prospects for pluripotent stem cell‐derived cardiomyocytes in cardiac cell therapy and as disease models (2009) (91)
- Regulation of stem cell therapies under attack in Europe: for whom the bell tolls (2013) (91)
- Differentiation of aggregated murine P19 embryonal carcinoma cells is induced by a novel visceral endoderm-specific FGF-like factor and inhibited by activin A (1991) (90)
- G1‐phase regulators, cyclin D1, cyclin D2, and cyclin D3: Up‐regulation at gastrulation and dynamic expression during neurulation (1998) (88)
- Heart repair and stem cells (2006) (88)
- Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification (2008) (88)
- Transforming growth factor-beta in the early mouse embryo: implications for the regulation of muscle formation and implantation. (1993) (87)
- Differential localization of TGF-beta 2 in mouse preimplantation and early postimplantation development. (1991) (86)
- Monitoring of cell therapy and assessment of cardiac function using magnetic resonance imaging in a mouse model of myocardial infarction (2007) (84)
- Improvement of mouse cardiac function by hESC-derived cardiomyocytes correlates with vascularity but not graft size. (2009) (83)
- Pluripotent stem cell models of human heart disease. (2013) (80)
- TECRL, a new life‐threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT (2016) (80)
- A new hERG allosteric modulator rescues genetic and drug‐induced long‐QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells (2016) (79)
- Commitment to differentiation induced by retinoic acid in P19 embryonal carcinoma cells is cell cycle dependent. (1987) (78)
- BMP4 Promotes EMT and Mesodermal Commitment in Human Embryonic Stem Cells via SLUG and MSX2 (2014) (78)
- Human Embryonic and Fetal Mesenchymal Stem Cells Differentiate toward Three Different Cardiac Lineages in Contrast to Their Adult Counterparts (2011) (76)
- Real time monitoring of BMP Smads transcriptional activity during mouse development (2008) (76)
- Preimplantation embryology: Expression of leukaemia inhibitory factor receptor subunits LIFRβ and gp 130 in human oocytes and preimplantation embryos (1996) (76)
- Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease models. (2011) (75)
- Dual Reporter MESP1mCherry/w‐NKX2‐5eGFP/w hESCs Enable Studying Early Human Cardiac Differentiation (2015) (73)
- Patterning the heart, a template for human cardiomyocyte development (2006) (73)
- Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes (2015) (72)
- Endoglin-mediated vascular remodeling: mechanisms underlying hereditary hemorrhagic telangiectasia. (2008) (71)
- Spatial and temporal expression of the β1D integrin during mouse development (1997) (70)
- Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies (2017) (69)
- Nitric Oxide Signaling in Oxytocin‐Mediated Cardiomyogenesis (2007) (69)
- Endoglin promotes TGF‐β/Smad1 signaling in scleroderma fibroblasts (2011) (68)
- Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes (2016) (68)
- NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network (2018) (67)
- Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes (2008) (67)
- Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes. (2013) (66)
- SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development. (2014) (65)
- Human Organs-on-Chips for Virology (2020) (64)
- Concise Review: Measuring Physiological Responses of Human Pluripotent Stem Cell Derived Cardiomyocytes to Drugs and Disease (2016) (64)
- PGC-1α and Reactive Oxygen Species Regulate Human Embryonic Stem Cell-Derived Cardiomyocyte Function (2013) (64)
- Functions of the TGFβ superfamily in human embryonic stem cells (2005) (63)
- Aggregation and cell cycle dependent retinoic acid receptor mRNA expression in P19 embryonal carcinoma cells (1992) (63)
- What if stem cells turn into embryos in a dish? (2015) (63)
- Differentiation of human embryonic stem cells to cardiomyocytes by coculture with endoderm in serum-free medium. (2007) (63)
- Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives (2019) (63)
- Differential expression of BMP receptors in early mouse development. (1997) (62)
- ENDOGLIN Is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-Induced Angiogenesis (2014) (62)
- BMP signalling differentially regulates distinct haematopoietic stem cell types (2015) (62)
- Cell cycle analysis during retinoic acid induced differentiation of a human embryonal carcinoma-derived cell line. (1987) (61)
- Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish. (2008) (61)
- CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function (2010) (61)
- Uncoupling DNA damage from chromatin damage to detoxify doxorubicin (2020) (61)
- Human embryonic stem cells: genetic manipulation on the way to cardiac cell therapies. (2005) (60)
- A short-term screening test for teratogens using differentiating neuroblastoma cells in vitro. (1984) (60)
- Activation of the Canonical Bone Morphogenetic Protein (BMP) Pathway during Lung Morphogenesis and Adult Lung Tissue Repair (2012) (60)
- Expression of transforming growth factor β2 during the differentiation of murine embryonal carcinoma and embryonic stem cells (1990) (59)
- Comparative analysis of 82 expressed sequence tags from a cattle ovary cDNA library (1998) (59)
- Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes (2014) (59)
- The first reported generation of human induced pluripotent stem cells (iPS cells) and iPS cell-derived cardiomyocytes in the Netherlands. (2010) (58)
- Regulation of cardiomyocyte differentiation of embryonic stem cells by extracellular signalling. (2007) (57)
- Expression patterns of laminin receptor splice variants α6Aβ1 and α6Bβ1 suggest different roles in mouse development (1995) (56)
- Smad expression during kidney development. (2004) (56)
- Snail is an immediate early target gene of parathyroid hormone related peptide signaling in parietal endoderm formation. (2000) (56)
- Two receptor classes for epidermal growth factor on pheochromocytoma cells, distinguishable by temperature, lectins, and tumor promoters (1985) (55)
- Altered primordial germ cell migration in the absence of transforming growth factor beta signaling via ALK5. (2005) (54)
- Induced pluripotent stem cells--a cautionary note. (2011) (54)
- Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes (2017) (53)
- EGF , epithelium and Gene ablation and TGF β superfamily function in mice 253 Functional analysis of the TGF β receptor / Smad pathway through gene ablation in mice (2000) (53)
- Cardiomyocyte differentiation from embryonic and adult stem cells. (2005) (53)
- Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes Under Defined Conditions. (2016) (52)
- A comprehensive gene expression analysis at sequential stages of in vitro cardiac differentiation from isolated MESP1-expressing-mesoderm progenitors (2016) (52)
- Modulation of functional and optimal (Na+‐K+)ATPase activity during the cell cycle of neuroblastoma cells (1981) (51)
- A practical guide for the identification of membrane and plasma membrane proteins in human embryonic stem cells and human embryonal carcinoma cells (2008) (51)
- Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva (2015) (50)
- Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells (2018) (50)
- Reply to Christ et al.: LQT1 and JLNS phenotypes in hiPSC-derived cardiomyocytes are due to KCNQ1 mutations (2015) (50)
- Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells (2018) (49)
- Expression of growth factors during the differentiation of embryonic stem cells in monolayer. (1990) (49)
- Growth factors and their receptors in differentiation and early murine development. (1990) (48)
- Isolation and characterization of permanent cell lines from inner cell mass cells of bovine blastocysts (1995) (48)
- Generation of induced pluripotent stem cells from human foetal fibroblasts using the Sleeping Beauty transposon gene delivery system. (2013) (48)
- Preferential expression of cellular retinoic acid binding protein in a subpopulation of neural cells in the developing mouse embryo. (1989) (47)
- Cardiology: Solace for the broken-hearted? (2005) (47)
- Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes (2017) (46)
- Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells (2017) (46)
- Differential expression of inhibin subunits and follistatin, but not of activin receptor type II, during early murine embryonic development. (1992) (46)
- DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells (2017) (46)
- MUSCLEMOTION (2018) (45)
- Functions of the TGFbeta superfamily in human embryonic stem cells. (2005) (45)
- Perspectives on the Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Biomedical Research (2018) (45)
- Pluripotent stem cell derived cardiovascular progenitors--a developmental perspective. (2015) (43)
- Generation of a floxed allele of the mouse endoglin gene (2007) (42)
- Proteomics and human embryonic stem cells. (2008) (42)
- Embryonic stem cell proteomics (2006) (42)
- Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes (2019) (41)
- A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes (2017) (40)
- SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development (2007) (40)
- Mouse embryonic stem cells with aberrant transforming growth factor beta signalling exhibit impaired differentiation in vitro and in vivo. (1998) (39)
- Impaired recruitment of HHT-1 mononuclear cells to the ischaemic heart is due to an altered CXCR4/CD26 balance. (2010) (39)
- A P19Cl6 GFP reporter line to quantify cardiomyocyte differentiation of stem cells. (2004) (39)
- Distribution of phosphorylated Smad2 identifies target tissues of TGF beta ligands in mouse development. (2003) (39)
- Receptor protein tyrosine phosphatase mu expression as a marker for endothelial cell heterogeneity; analysis of RPTPmu gene expression using LacZ knock-in mice. (2003) (39)
- Progenitor cells for cardiac repair. (2007) (38)
- Building blocks for a European Organ-on-Chip roadmap. (2019) (37)
- The cell cycle, cell death, and cell morphology during retinoic acid-induced differentiation of embryonal carcinoma cells. (1984) (37)
- Epidermal growth factor receptor expression during morphological differentiation of pheochromocytoma cells, induced by nerve growth factor or dibutyryl cyclic AMP (1987) (36)
- Modulations of NA+ transport during the cell cycle of neuroblastoma cells (1982) (36)
- Human stem cells as a model for cardiac differentiation and disease (2009) (36)
- Cardiovascular development: towards biomedical applicability (2007) (35)
- International Coordination of Large-Scale Human Induced Pluripotent Stem Cell Initiatives: Wellcome Trust and ISSCR Workshops White Paper (2014) (35)
- Sox2 Transduction Enhances Cardiovascular Repair Capacity of Blood-Derived Mesoangioblasts (2010) (35)
- Inhibition of ROCK improves survival of human embryonic stem cell–derived cardiomyocytes after dissociation (2010) (35)
- Identification and characterization of polypeptide growth factors secreted by murine embryonal carcinoma cells. (1989) (35)
- Cardiomyocytes from human embryonic stem cells. (2006) (34)
- The role of TGF‐β production in growth inhibition of breast‐tumor cells by progestins (1995) (34)
- Model systems for cardiovascular regenerative biology. (2013) (34)
- Cardiomyocytes from human and mouse embryonic stem cells. (2007) (34)
- Fibroblast Growth Factor-Mediated Growth Regulation and Receptor Expression in Embryonal Carcinoma and Embryonic Stem Cells and Human Germ Cell Tumors (1993) (33)
- Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs) (2017) (33)
- Transforming growth factor β and mouse development (2001) (33)
- Cardiomyocytes derived from stem cells (2005) (33)
- Stage‐specific appearance of the mouse antigen TEC‐3 in normal and nuclear transfer bovine embryos: Re‐expression after nuclear transfer (1994) (33)
- Synthesis and regulation of leukaemia inhibitory factor in cultured bovine oviduct cells by hormones. (1998) (33)
- Scalable microphysiological system to model three-dimensional blood vessels (2019) (33)
- Knock-in of integrin β1D affects primary but not secondary myogenesis in mice (2003) (33)
- Feeder‐Free Monolayer Cultures of Human Embryonic Stem Cells Express an Epithelial Plasma Membrane Protein Profile (2008) (32)
- Readthrough-Promoting Drugs Gentamicin and PTC124 Fail to Rescue Nav1.5 Function of Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes Carrying Nonsense Mutations in the Sodium Channel Gene SCN5A (2016) (32)
- BMP and Hedgehog Regulate Distinct AGM Hematopoietic Stem Cells Ex Vivo (2016) (32)
- Cytostretch, an Organ-on-Chip Platform (2016) (31)
- Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes (2020) (31)
- Identification of two distinct functions for TGF-β in early mouse development (1998) (31)
- Polycistronic lentivirus induced pluripotent stem cells from skin biopsies after long term storage, blood outgrowth endothelial cells and cells from milk teeth. (2013) (30)
- Localization and quantification of epidermal growth factor receptors on single cells by confocal laser scanning microscopy. (1992) (30)
- The composition and differentiation potential of the duodenal intraepithelial innate lymphocyte compartment is altered in coeliac disease (2015) (30)
- Expression of leukaemia inhibitory factor receptor subunits LIFR beta and gp130 in human oocytes and preimplantation embryos. (1996) (30)
- Production of insulin-like growth factors, platelet-derived growth factor, and transforming growth factors and their role in the density-dependent growth regulation of a differentiated embryonal carcinoma cell line. (1989) (30)
- Inherited heart disease – what can we expect from the second decade of human iPS cell research? (2016) (30)
- Secretion of transforming growth factor‐β isoforms by embryonic stem cells: Isoform and latency are dependent on direction of differentiation (1993) (30)
- Expression of the alpha 6A integrin splice variant in developing mouse embryonic stem cell aggregates and correlation with cardiac muscle differentiation. (1999) (29)
- Expression of TGF‐β stimulated clone‐22 (TSC‐22) in mouse development and TGF‐β signalling (2000) (29)
- Molecular cloning, genetic mapping, and developmental expression of a bovine transforming growth factor beta (TGF‐β) type I receptor (1998) (28)
- Generation, functional analysis and applications of isogenic three-dimensional self-aggregating cardiac microtissues from human pluripotent stem cells (2021) (28)
- BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells (2015) (27)
- In vitro modelling of alveolar repair at the air-liquid interface using alveolar epithelial cells derived from human induced pluripotent stem cells (2020) (27)
- Differentiation-Defective Human Induced Pluripotent Stem Cells Reveal Strengths and Limitations of the Teratoma Assay and In Vitro Pluripotency Assays (2017) (27)
- Correction: Corrigendum: BMP signalling differentially regulates distinct haematopoietic stem cell types (2015) (27)
- A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo (2018) (27)
- Genetically Engineered Mesenchymal Stem Cells Influence Gene Expression in Donor Cardiomyocytes and the Recipient Heart. (2012) (26)
- Human stem cell models for predictive cardiac safety pharmacology. (2010) (26)
- Implantation and Placentation (2008) (26)
- Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposure. (2015) (26)
- Expression of the inhibitory Smad7 in early mouse development and upregulation during embryonic vasculogenesis (2000) (26)
- Direct visualization of Smad1/5/8‐mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys (2011) (25)
- Loss of EGF binding and cation transport response during differentiation of mouse neuroblastoma cells (1983) (25)
- Squaramide-Based Supramolecular Materials for Three-Dimensional Cell Culture of Human Induced Pluripotent Stem Cells and Their Derivatives (2018) (25)
- Antireceptor antibodies in the study of EGF-receptor interaction. (1987) (25)
- Visceral endoderm induces specification of cardiomyocytes in mice. (2009) (24)
- Inherited cardiac diseases, pluripotent stem cells, and genome editing combined—the past, present, and future (2019) (24)
- Type beta transforming growth factors and activins in differentiating embryonal carcinoma cells, embryonic stem cells and early embryonic development. (1993) (24)
- Direct cardiomyocyte reprogramming: a new direction for cardiovascular regenerative medicine. (2013) (24)
- Ectopic expression of the transforming growth factor β type II receptor disrupts mesoderm organisation during mouse gastrulation (1999) (24)
- A cardiomyocyte show of force: A fluorescent alpha-actinin reporter line sheds light on human cardiomyocyte contractility versus substrate stiffness. (2020) (24)
- Cryopreservation of human pluripotent stem cell-derived cardiomyocytes is not detrimental to their molecular and functional properties (2019) (23)
- Bone morphogenetic proteins (BMPs) induce epithelial differentiation of NT2D1 human embryonal carcinoma cells. (2000) (23)
- Protein kinase C and phorbol ester receptor expression related to growth and differentiation of nullipotent and pluripotent embryonal carcinoma cells. (1986) (23)
- Using Cardiovascular Cells from Human Pluripotent Stem Cells for COVID-19 Research: Why the Heart Fails (2020) (23)
- Screening for cytotoxicity in neuroblastoma cells. I. Dependence of growth inhibition on the presence of serum. (1983) (22)
- Engineered models of the human heart: Directions and challenges (2020) (22)
- Transforming growth factor beta and mouse development. (2001) (22)
- Proteomic analysis of stem cell differentiation and early development. (2012) (22)
- Developmental tumours, early differentiation and the transforming growth factor beta superfamily. (1999) (22)
- Co‐Differentiation of Human Pluripotent Stem Cells‐Derived Cardiomyocytes and Endothelial Cells from Cardiac Mesoderm Provides a Three‐Dimensional Model of Cardiac Microtissue (2017) (22)
- Spatial and temporal expression of the beta1D integrin during mouse development. (1997) (21)
- Characterization of 42K+ and 86Rb+ transport and electrical membrane properties in exponentially growing neuroblastoma cells. (1981) (21)
- Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation (2009) (21)
- Sorting cardiomyocytes: a simple solution after all? (2010) (21)
- Differentially regulated production of platelet-derived growth factor and of transforming growth factor beta by a human teratocarcinoma cell line. (1988) (21)
- Unlocking Personalized Biomedicine and Drug Discovery with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Fit for Purpose or Forever Elusive? (2020) (21)
- The MicroRNA-371 Family as Plasma Biomarkers for Monitoring Undifferentiated and Potentially Malignant Human Pluripotent Stem Cells in Teratoma Assays (2018) (20)
- Human embryonic stem cells: towards therapies for cardiac disease. Derivation of a Dutch human embryonic stem cell line. (2005) (20)
- Smooth muscle diversity from human pluripotent cells (2012) (20)
- Regulation of Growth Factors and their Receptors in Early Murine Embryogenesis (1989) (19)
- Knock-in of integrin beta 1D affects primary but not secondary myogenesis in mice. (2003) (19)
- Culture of bovine embryos to the blastocyst stage using Buffalo rat liver (BRL) cells. (1995) (18)
- Decreased Expression of Vascular Endothelial Growth Factor Receptor 1 Contributes to the Pathogenesis of Hereditary Hemorrhagic Telangiectasia Type 2 (2018) (18)
- Interaction Between ALK1 Signaling and Connexin40 in the Development of Arteriovenous Malformations (2016) (18)
- Organs-on-Chips in Drug Development: The Importance of Involving Stakeholders in Early Health Technology Assessment (2016) (18)
- Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells to Cardiomyocytes (2012) (18)
- A Miniaturized EHT Platform for Accurate Measurements of Tissue Contractile Properties (2020) (18)
- The time is right: proteome biology of stem cells. (2008) (17)
- Follow-up of Thalidomide treatment in patients with Hereditary Haemorrhagic Telangiectasia. (2015) (17)
- Activation of both transforming growth factor-β and bone morphogenetic protein signalling pathways upon traumatic brain injury restrains pro-inflammatory and boosts tissue reparatory responses of reactive astrocytes and microglia (2019) (17)
- Lymphangiogenesis and angiogenesis during human fetal pancreas development (2014) (17)
- Stem cell research: immortality or a healthy old age? (2004) (17)
- Monovalent cation transport during the cell cycle (review). (1982) (16)
- Isogenic Sets of hiPSC-CMs Harboring Distinct KCNH2 Mutations Differ Functionally and in Susceptibility to Drug-Induced Arrhythmias (2020) (16)
- From Stealing Fire to Cellular Reprogramming: A Scientific History Leading to the 2012 Nobel Prize (2013) (16)
- Is heart regeneration on the right track? (2013) (16)
- Generation and Functional Characterization of Monocytes and Macrophages Derived from Human Induced Pluripotent Stem Cells (2020) (15)
- Organization of non-muscle myosin during early murine embryonic differentiation. (1992) (15)
- Cardiomyocytes from human embryonic stem cells: more than heart repair alone. (2007) (15)
- Engineered 3D vessel-on-chip using hiPSC-derived endothelial- and vascular smooth muscle cells (2021) (15)
- Identification of the type-B receptor for platelet-derived growth factor in human embryonal carcinoma cells. (1990) (14)
- Transforming growth factor-β and its receptor are differentially regulated in human embryonal carcinoma cells (1989) (14)
- Characterization of polyclonal anti-peptide antibodies specific for transforming growth factor beta 2. (1990) (14)
- Adenovirus E1A antagonizes both negative and positive growth signals elicited by transforming growth factor beta 1. (1995) (14)
- Strategies for rapidly mapping proviral integration sites and assessing cardiogenic potential of nascent human induced pluripotent stem cell clones. (2014) (14)
- Cell to Cell Signals in Mammalian Development (1989) (14)
- Getting to the heart of the matter: direct reprogramming to cardiomyocytes. (2010) (14)
- Expression patterns of laminin receptor splice variants alpha 6A beta 1 and alpha 6B beta 1 suggest different roles in mouse development. (1995) (14)
- Cadmium-induced inhibition of proliferation and differentiation of embryonal carcinoma cells and mechanistic aspects of protection by zinc. (1993) (14)
- Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation (2019) (13)
- Effects of feeder layer and BRL conditioned medium on mouse embryonic stem cells (1990) (13)
- Stem cells: The cancer's gone, but did chemotherapy damage your heart? (2016) (13)
- Cytostretch , an Organon-Chip Platform (2016) (12)
- Proteome biology of stem cells. (2007) (12)
- Quantification of Muscle Contraction In Vitro and In Vivo Using MUSCLEMOTION Software: From Stem Cell‐Derived Cardiomyocytes to Zebrafish and Human Hearts (2018) (12)
- Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart (2017) (12)
- Quantitative Analysis of Intracellular Ca2+ Release and Contraction in hiPSC-Derived Vascular Smooth Muscle Cells (2019) (12)
- Human teratocarcinoma cells express functional insulin-like growth factor I receptors. (1989) (11)
- Fibroblast growth factor-mediated growth regulation and receptor expression in embryonal carcinoma and embryonic stem cells and human germ cell tumours. (1993) (11)
- Executive summary of the 12th HHT international scientific conference (2018) (11)
- Conversion of Mature Human b-Cells Into Glucagon- Producing a-Cells (2013) (11)
- Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells (2021) (11)
- Survey of neuropeptide gene expression in tumor cell lines. (1992) (10)
- Cardiomyocyte reprogramming and the new age of cellular alchemy. (2012) (10)
- Identification of two distinct functions for TGF-beta in early mouse development. (1998) (10)
- The plasma membrane as the primary target for the action of growth factors and tumour promoters in development (1983) (10)
- Differential regulation of JunB and JunD by adenovirus type 5 and 12 E1A proteins. (1991) (10)
- Genetic manipulation of human embryonic stem cells in serum and feeder-free media. (2010) (10)
- Cardiac Tissues From Stem Cells (2021) (9)
- Differentiation in Early Development (2013) (9)
- Screening for cytotoxicity in neuroblastoma cells. II. Growth inhibition: cell death or impaired cell cycle progression? (1983) (9)
- Cytoskeletal heart-enriched actin-associated protein (CHAP) is expressed in striated and smooth muscle cells in chick and mouse during embryonic and adult stages. (2011) (9)
- Bone morphogenetic proteins and retinoic acid induce human endogenous retrovirus HERV‐K expression in NT2D1 human embryonal carcinoma cells (2000) (9)
- Is TNFalpha really a good therapeutic target in motoneuronal degeneration? A case of amyotrophic lateral sclerosis in a patient with RA receiving infliximab. (2006) (9)
- Fabrication and Characterization of an Upside-Down Carbon Nanotube Microelectrode Array (2016) (8)
- Transplantation of human embryonic stem cell-derived cardiomyocytes in mice (2006) (8)
- Regenerative medicine funding policies in Europe and The Netherlands (2017) (8)
- Proteome Biology of Stem Cells (2008) (8)
- Stem Cells: Scientific Facts and Fiction (2010) (8)
- Shedding new light on the mechanism underlying stem cell therapy for the heart. (2011) (8)
- Na+/H+ EXCHANGE IN THE ACTION OF GROWTH FACTORS1 (1982) (8)
- Advantages of the avian model for human ovarian cancer. (2015) (8)
- Expandable human cardiovascular progenitors from stem cells for regenerating mouse heart after myocardial infarction (2019) (7)
- Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes. (2016) (7)
- Cation transport and growth control in neuroblastoma cells in culture. (1982) (7)
- Regulation of growth and differentiation in early development: Of mice and models (1993) (6)
- Targeting the Kv11.1 (hERG) channel with allosteric modulators. Synthesis and biological evaluation of three novel series of LUF7346 derivatives. (2020) (6)
- New perspectives on regeneration of the heart. (2011) (6)
- Bone Morphogenetic Proteins ( BMPs ) induce epithelial differentiation of NT 2 D 1 human embryonal carcinoma cells (2000) (6)
- Spatial and Temporal Expression of the b1D Integrin During Mouse Development (1997) (6)
- Transforming growth factor‐βs in pre‐gastrulation development of mammals (minireview) (2000) (6)
- Evidence generation and reproducibility in cell and gene therapy research: A call to action (2021) (6)
- The avian embryo to study development of the cardiac conduction system. (2016) (6)
- Rapid Prototyping of Organ-on-a-Chip Devices Using Maskless Photolithography (2021) (6)
- Spotlight on stem cells--makes old hearts fresh. (2003) (6)
- NOBEL 2012 Physiology or medicine: Mature cells can be rejuvenated (2012) (6)
- Tbx6 is a determinant of cardiac and neural cell fate decisions in multipotent P19CL6 cells. (2012) (6)
- Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids (2022) (6)
- Upside-down Carbon nanotube (CNT) micro-electrode array (MEA) (2015) (5)
- New and viable cells to replace lost and malfunctioning myocardial tissue. (2004) (5)
- Human stem cells shape the future of cardiac regeneration research. (2004) (5)
- Expression of transforming growth factor beta 2 during the differentiation of murine embryonal carcinoma and embryonic stem cells. (1990) (5)
- CCN2 reduction mediates protective effects of BMP7 treatment in obstructive nephropathy (2016) (5)
- Generation and genetic repair of two human induced pluripotent cell lines from patients with Epidermolysis Bullosa simplex and dilated cardiomyopathy associated with a heterozygous mutation in the translation initiation codon of KLHL24. (2021) (5)
- Fibronectin Patches as Anchoring Points for Force Sensing and Transmission in Human Induced Pluripotent Stem Cell-Derived Pericytes (2020) (5)
- Welcome to Stem Cell Reports (2013) (5)
- Quantifying Ca2+ signaling and contraction in vascular pericytes and smooth muscle cells. (2019) (5)
- The Linkage Phase of the Polymorphism KCNH2-K897T Influences the Electrophysiological Phenotype in hiPSC Models of LQT2 (2021) (5)
- Cell replacement therapies: is it time to reprogram? (2014) (5)
- What Endothelial Cells from Patient iPSCs Can Tell Us about Aortic Valve Disease. (2015) (4)
- New guidelines for embryo and stem cell research (2021) (4)
- Maturation of hiPSC-derived cardiomyocytes promotes adult alternative splicing of SCN5A and reveals changes in sodium current associated with cardiac arrhythmia (2022) (4)
- Microfluidic Assay for the Assessment of Leukocyte Adhesion to Human Induced Pluripotent Stem Cell-derived Endothelial Cells (hiPSC-ECs). (2018) (4)
- Mentorship in Science: Response to AlShebli et al., Nature Communications 2020 (2021) (4)
- Pressure-Driven Perfusion System to Control, Multiplex and Recirculate Cell Culture Medium for Organs-on-Chips (2022) (4)
- Reprogramming Urine‐Derived Cells using Commercially Available Self‐Replicative RNA and a Single Electroporation (2020) (4)
- Transforming growth factor-beta and its receptor are differentially regulated in human embryonal carcinoma cells. (1989) (4)
- SnapShot: Key Advances in hiPSC Disease Modeling. (2016) (4)
- Faculty Opinions recommendation of Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium. (2018) (4)
- Vascular Tumor Recapitulated in Endothelial Cells from hiPSCs Engineered to Express the SERPINE1-FOSB Translocation (2020) (4)
- What are stem cells? (2021) (4)
- STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells (2022) (4)
- Genetic selection of cardiomyocytes from human embryonic stem cells. (2007) (3)
- Current controversies in prenatal diagnosis 1: is stem cell therapy ready for human fetuses? (2011) (3)
- Growth factors and receptors during differentiation: a comparison of human and murine embryonal carcinoma cell lines. (1991) (3)
- Regulation of intracellular pH during the G1/S-phase transition of the neuroblastoma cell cycle. (1988) (3)
- Isogenic induced pluripotent stem cells (IPSCS) derived from mosaic hereditary hemorrhagic telangiectasia type 1 (HHT1) patient (2018) (3)
- Comprar Stem Cells. Scientific Facts And Fiction | C. Mummery | 9780123815354 | Academic Press (2010) (3)
- Stem cells: Cloning human embryos (2013) (3)
- Position Paper of the ESC Working Group Cellular Biology of the Heart : Cell-Based Therapies for Myocardial Repair and Regeneration in Ischemic Heart Disease and Heart Failure (2016) (3)
- Vasculogenesis and Angiogenesis: Lessons From Genetics in Mice (2002) (3)
- Thresholds of Endoglin Expression in Endothelial Cells Explains Vascular Etiology in Hereditary Hemorrhagic Telangiectasia Type 1 (2021) (3)
- Stem Cells in Cancer and Cancer Stem Cells (2011) (2)
- Generation of AAVS1 and CLYBL STRAIGHT-IN v2 acceptor human iPSC lines for integrating DNA payloads. (2022) (2)
- Pluripotent stem cells: biology and applications: Durango Colorado, 6-11 February 2001. (2001) (2)
- Generation and genetic repair of 2 iPSC clones from a patient bearing a heterozygous c.1120del18 mutation in the ACVRL1 gene leading to Hereditary Hemorrhagic Telangiectasia (HHT) type 2. (2020) (2)
- CRISPR/Cas9-Mediated Introduction of Specific Heterozygous Mutations in Human Induced Pluripotent Stem Cells. (2021) (2)
- Expression of OCT-4 transcription factor in bovine oocytes and embryos☆ (1997) (2)
- Assessment of functional competence of endothelial cells from human pluripotent stem cells in zebrafish embryos. (2014) (2)
- Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells. (2022) (2)
- Heart defects recapitulated in human cardioids (2021) (2)
- Vascular defects associated with hereditary hemorrhagic telangiectasia revealed in patient-derived isogenic iPSCs in 3D vessels on chip (2022) (2)
- Interpretation of fi eld potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes (2018) (2)
- Mesodermal Differentiation of Embryonal Carcinoma Cells in Coculture with Visceral Endoderm Cell Lines (1989) (2)
- Somatic stem cells and cardiac repair: where is the science? (2004) (2)
- Harnessing the power of cardiac stem cells (2016) (2)
- Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (2021) (2)
- Regulation of growth and differentiation in early development: of mice and models. (1989) (2)
- Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in the Evaluation of Cardiotoxic Potential of Drugs (2018) (2)
- Versatile open software to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo (2017) (2)
- Abstract 3898: Human Cardiomyocyte Progenitor Cells Regenerate Infarcted Myocardium and Preserve Long-Term Cardiac Function in Mice (2008) (2)
- Differentiation of Hematopoietic Stem Cells from Embryonic Stem Cells (2004) (2)
- Welcome to the special issue on organs-on-chip from the guest editors (2021) (1)
- chapter 6 – Toward Stem Cell Therapy (2004) (1)
- Chapter 2 – Embryonic Development (2011) (1)
- A platform for assessing pro- and anti-arrhythmic effects of drugs based on isogenic human iPSC-derived cardiomyocytes (2019) (1)
- Abstract 554: Human Embryonic Stem Cell-Derived Cardiomyocytes Survive and Mature after Intramyocardial Transplantation in the Mouse Heart (2006) (1)
- Of Mice and Men: The History of the Stem Cell (2011) (1)
- A Case for Crowd Sourcing in Stem Cell Research (2014) (1)
- Human Embryonic Stem Cells (2011) (1)
- Chapter 2 Immaturity of stem-cell derived cardiomyocytes : fatal fl aw or soluble problem ? (2017) (1)
- The biology of the cell (2021) (1)
- Software Tool for Automatic Quantification of Sarcomere Length and Organization in Fixed and Live 2D and 3D Muscle Cell Cultures In Vitro (2022) (1)
- ETV2 Upregulation Marks the Specification of Early Cardiomyocytes and Endothelial Cells During Co-differentiation (2022) (1)
- Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene. (2020) (1)
- On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010. (2010) (1)
- Lymphoblast-derived hiPS cell lines generated from four individuals of a family of genetically unrelated parents and their female monozygotic twins. (2019) (1)
- A miniaturized EHT platform for contractile tissue measurements (2019) (1)
- Stem cell tourism (2021) (1)
- NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network (2018) (1)
- Cardiomyocyte Differentiation of Human Pluripotent Stem Cells (2012) (1)
- Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy (2023) (1)
- Chapter 4 A splice site mutation in TECRL is associated with inherited lethal arrhythmias in humans (2016) (1)
- Stem Cells and Cardiomyocytes (2006) (1)
- Cancer stem cells: where do they come from and where are they going? (2021) (1)
- Challenges and potential in regenerative medicine: A joint report from EASAC and FEAM (2020) (1)
- Optogenetic Reporters Delivered as mRNA Facilitate Repeatable Action Potential and Calcium Handling Assessment in Human iPSC-Derived Cardiomyocytes (2022) (1)
- Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes (2017) (1)
- Supplemental Information Complex Tissue and Disease Modeling using hiPSCs (2016) (1)
- Regulation of the cell cycle in neuroblastoma cells: the role of ion transport. (1982) (1)
- STRAIGHT-IN: A platform for high-throughput targeting of large DNA payloads into human pluripotent stem cells (2021) (1)
- Chapter 10 – Differentiation in Early Development (2014) (1)
- Integration of embryonic stem cells into murine embryos (1989) (1)
- Human stem cells for organs-on-chips: “clinical trials” without patients? (2021) (1)
- Organ-on-Chip In Development : Towards a European roadmap for Organon-Chip (2018) (1)
- Efficacy and Safety of Tacrolimus as Treatment for Bleeding Caused by Hereditary Hemorrhagic Telangiectasia: An Open-Label, Pilot Study (2022) (1)
- Simultaneous measurement of contraction, voltage and calcium in HIPSC-CMS for the detection of inotropic effects under blinded conditions. (2019) (1)
- The EHA Research Roadmap: Hematopoietic Stem Cells and Allotransplantation (2022) (1)
- Generation of three human induced pluripotent stem cell lines, LUMCi024-A, LUMCi025-A, and LUMCi026-A, from two patients with combined oxidative phosphorylation deficiency 8 and a related control. (2021) (1)
- Faculty Opinions recommendation of Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons. (2018) (0)
- Spatio-temporally restricted expression of the cellular retinoic acid binding protein in the developing embryo (1989) (0)
- Stem cells for discovery of effective and safe new drugs (2021) (0)
- Issue Information-Mission & Focus. (2016) (0)
- Faculty Opinions recommendation of A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia. (2019) (0)
- Women in Stem Cell Science: Part I (2018) (0)
- Expression and transcriptional regulation of the kFGF gene in embryonal carcinoma cells (1989) (0)
- Organ-on-Chip : A synthetic mimic for human myocardium (2016) (0)
- Human embryonic stem cell derived cardiomyocytes for use in cardiac safety pharmacology (2011) (0)
- Immunolocalization of in mouse preimplantation-embryos (1989) (0)
- Cardiomyocyte Differentiation in Human ES Cells (2007) (0)
- Three‐Dimensional Vessels‐on‐a‐Chip Based on hiPSC‐derived Vascular Endothelial and Smooth Muscle Cells (2022) (0)
- 1 WHY STUDY PROTEOMICS IN STEM CELLS AND DEVELOPMENT ? (2012) (0)
- Teratoma Assay for Testing Pluripotency and Malignancy of Stem Cells: Insufficient Reporting and Uptake of Animal-Free Methods—A Systematic Review (2023) (0)
- Part A: Directed Differentiation of Human Embryonic Stem Cells into Cardiomyocytes (2007) (0)
- Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (2022) (0)
- 14-P023 Mouse pluripotent stem cell models of a human cardiac sodium channelopathy (2009) (0)
- Abstract P028: The Effect of Cotransplantation of Human Embryonic Stem Cell--Derived Cardiomyocytes and Mesenchymal Stem Cells on Ventricular Function and Remodeling After Myocardial Infarction in Nude Rats (2011) (0)
- Cardiomyocytes from stem cells: what can we do with them? (2021) (0)
- Improved functional maturation of human induced pluripotent stem cell (hiPSC) derived ventricular cardiomyocytes in vitro : Multi-electrode array (MEA) based electrophysiological characterization (2016) (0)
- Tissue microenvironment dictates the state of human induced pluripotent stem cell-derived endothelial cells of distinct developmental origin in 3D cardiac microtissues (2022) (0)
- Regenerative medicine: clinical applications of stem cells (2021) (0)
- PGC-1α and reactive oxygen species regulate hESC-derived cardiomyocyte function (2017) (0)
- Organs-on-chips: into the next decade (2020) (0)
- Differenciation de cellules souches embryonnaires humaines en cardiomyocytes (2004) (0)
- The ability to generate functional cardiovascular (progenitor) cells from human pluripotent stem cells is beginning to offer unprecedented opportunities for translational research in cardiac medicine. Applications range from the use of cells to study early human cardiac development, the development (2010) (0)
- Extraordinary challenge, extraordinary achievement: 2020–2021 year in review (2021) (0)
- Organ on Chip in Development (ORCHID) (2017) (0)
- Early differentiation in mammalian development (2002) (0)
- On-chip analysis of glycolysis and mitochondrial respiration in human induced pluripotent stem cells (2022) (0)
- genomic coordinates of the mouse CAGE peaks (2017) (0)
- Cellular assays for monitoring cardiomyocyte electrophysiology (2013) (0)
- Assessing Pluripotency of Human Pluripotent Stem Cells: Challenges for the Pathologist (2016) (0)
- Abstract 14863: Genetically Engineered Mesenchymal Stem Cells Confer Beneficial Effects on Both Co-transplanted Human Embryonic Stem Cell Derived Cardiomyocytes as well as the Recipient Heart (2010) (0)
- Towards Human Embryonic Stem Cell Derived Cardiomyocytes (2002) (0)
- Quantifying Importance of Repolarization Currents Underlying Physiological Variability in Rabbit Cellular Electrophysiology (2012) (0)
- Engineering multicellular living systems—a Keystone Symposia report (2022) (0)
- Her heart yearned for Boston: a few questions for Christine Mummery. (2008) (0)
- Of mice and men: the history of embryonic stem cells (2021) (0)
- Celebrating 10 years of hESC lines: an interview with Christine Mummery. Interviewed by Miodrag Stojković and Susan Daher. (2009) (0)
- Alpha-Actinin-mCherry fusion protein Building a paramount new tool for cardiomyocyte analysis (2016) (0)
- Establishing optimal culture conditions for electrophysiological characterization of human pluripotent stem cell-derived cardiomyocytes (2017) (0)
- Vascular deficiency in ALK5 knock-in mice (2006) (0)
- e role of CHAP during heart development: in vivo and in vitro knockdown in mouse and chick (2013) (0)
- Chapter Human induced pluripotent stem cells from pa (cid:415) ents with familial hypertrophic cardiomyopathy (2014) (0)
- Mouse Pluripotent Stem Cell Models of a Human Cardiac Sodium Channelopathy (2010) (0)
- Introduction of a Geminin mScarlet Reporter into H2B-mTurq2 hiPSCs for Live-cell Imaging of Proliferation and Cell Cycling. (2023) (0)
- CCN2 reduction mediates protective effects of BMP7 treatment in obstructive nephropathy (2016) (0)
- Abstract 5280: Comparing Epigenetic Modifications of Adult Progenitor Cells (2009) (0)
- Isogenic sets of hiPSC-CMs harboring KCNH2 mutations capture location-related phenotypic differences (2019) (0)
- Cardiovascular derivatives of pluripotent stem cell s in cardiac repair, drug discovery and disease (2010) (0)
- Lab on a Chip Modular microreactor with integrated reflection element for online reaction monitoring using infrared spectroscopy † (2013) (0)
- CHAPTER E)dhe)dgnaVi^dc YncVb^XhYjg^c\ ZVganY^ZgZci^Vi^dc d()jbVcZbWgndc^X hiZbXZaah (2009) (0)
- The role of endoglin in induction and repair of cardiovascular damage after radiation alone or in combinatione with trastuzumab (Herceptin) (2008) (0)
- Faculty Opinions recommendation of Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells. (2019) (0)
- Perspectives for Future Use of Cardiac Microtissues from Human Pluripotent Stem Cells (2022) (0)
- Monitoring Undifferentiated and Potentially Malignant Human Pluripotent Stem Cells for Clinical Applications (2020) (0)
- Isogenic Sets of Human Pluripotent Stem Cells as Model of LQT2 Syndrome (2014) (0)
- Chapter 6 – Cloning (2011) (0)
- Related articles (2013) (0)
- Stem cells in veterinary medicine (2021) (0)
- Hypertrophic Cardiomyopathy - Impaired sarcomeric motion and contractile dysfunction caused by defective MYBPC3 in hPSC derived cardiomyocytes (2016) (0)
- Faculty Opinions recommendation of Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjögren syndrome. (2012) (0)
- The TGB-β family in endothelial cell differentiation and cardiovascular development and function (2008) (0)
- Cell therapy approaches for treatment of bradyarrhythmias (2020) (0)
- sample information of the human samples (2017) (0)
- Cation Transport during the Cell Cycle of Neuroblastoma Cells (1985) (0)
- O rigin and use of embryonic and adult stem cells in differentiation and tissue repair (2003) (0)
- Differentiation and functionality of endothelial cells and pericytes from human induced pluripotent stem cells (2014) (0)
- Lab on a Chip (2019) (0)
- assay information of the mouse qualitycontrol samples for HeliScopeCAGE (2017) (0)
- In vitro overexpression of CHAPa and CHAPb in mouse cardiomyocytes and skeletal muscle cells interferes with Z-disc integrity and decreases fetal gene expression (2013) (0)
- DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells (2017) (0)
- Recent withdrawals of prescription drugs from clinical use because of unexpected side effects on the heart have highlighted the need for more reliable cardiac safety pharmacology assays. Block of the human Ether-a-go go Related Gene (hERG) ion (2010) (0)
- skip a beat : studying cardiac rhythm in human pluripotent stem cell-derived cardiomyocytes (2016) (0)
- Cloning: history and current applications (2021) (0)
- OoC-NRDD 2019 1 Organs-on-chips : into the next decade 1 (2020) (0)
- O22. Cardiovascular derivatives of embryonic stem cells in cardiac repair and drug discovery (2010) (0)
- WITHDRAWN: Human stem cell models for predictive cardiac safety pharmacology (2010) (0)
- Abstract 281: Studying Structural And Contractility Defects Of Cardiomyocytes In An In Vitro Model Of Human Hypertrophic Cardiomyopathy (2013) (0)
- Stem cell perspectives: a vision of the future (2021) (0)
- P▪36 Cytogenetic abnormalities in human embryonic stem cell lines (2005) (0)
- Challenges of immaturity and proliferation in using hPSC-derived cardiomyocytes as disease models (2016) (0)
- Z-disc protein CHAPb induces cardiomyopathy and diastolic dysfunction (2013) (0)
- Efficacy of physiotherapy treatment for female urinary incontinence (1999) (0)
- Characterizing micro-mechanical viscoelastic properties of soft tissues and (bio)materials in physiological-like conditions (Conference Presentation) (2018) (0)
- THE SCN5A1795INSD/+ MUTATION RESULTS IN INCREASED INTRACELLULAR CALCIUM CONCENTRATIONS IN HUMAN CARDIOMYOCYTES DERIVED FROM INDUCED PLURIPOTENT STEM CELLS (2014) (0)
- Extraordinary challenge, extraordinary achievement: 2019–2020 year in review (2021) (0)
- InPulse CrackIT Challenge: Development of An In Vitro Platform Using Physiologically Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Screen for Drug-Induced Effects on Cardiac Contractility (2017) (0)
- Stem cell based model systems for drug target discovery and cardiac safety pharmacology (2010) (0)
- Microphysiological stem cell models of the human heart (2022) (0)
- Miniaturized engineered heart tissues from HiPSC-derived co-culture (2020) (0)
- Chapter 2 Treating Cardiac Disorders with Stem Cells (2019) (0)
- Patents, opportunities, and challenges: legal and intellectual property issues associated with stem cells (2021) (0)
- Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralization (2022) (0)
- 24 The TGF-β Family in Endothelial Cell Differentiation and Cardiovascular Development and Function (2008) (0)
- The Next Chapter for Stem Cell Reports (2018) (0)
- Highly Reproducible Tissue Positioning with Tapered Pillar Design in Engineered Heart Tissue Platforms (2023) (0)
- P93. Human germ cells development during the first trimester—X chromosome activity in human germ cells (2010) (0)
- Treating Cardiac Disorders with Stem Cells (2011) (0)
- genomic coordinates of the human CAGE peaks (2017) (0)
- IDENTIFICATION OF BMP 9 AS THE SPECIFIC LIGAND OF ALK 1 : A NEW CIRCULATING ANGIOGENIC FACTOR (2007) (0)
- Genetic correction of the W156X mutation in a patient- specific hiPSC line carrying compound heterozygous mutations in the SCN5A gene (2017) (0)
- Faculty Opinions recommendation of Human Mesenchymal Stromal Cells Are Resistant to SARS-CoV-2 Infection under Steady-State, Inflammatory Conditions and in the Presence of SARS-CoV-2-Infected Cells. (2020) (0)
- Mononuclear cells in patients with hereditary haemorrhagic telangiectasia (HHT) are defective in their homing and differentiation capacity in vivo (2006) (0)
- Regenerative medicine funding policies in Europe and The Netherlands (2017) (0)
- expression table of the human CAGE peaks (2017) (0)
- Profiling and function of signal transduction and integrin pathways in human embryonic stem cells (2004) (0)
- Molecular cloning of early retinoid acid responsive genes from synchronized P19 EC cells using a subtractive hybridization technique (1989) (0)
- Embryonic development (2021) (0)
- Phenotypic changes in EC cells and their differentiated derivatives induced by the adenovirus E1A gene (1989) (0)
- Expansion and developmental patterning of human PSC-derived cardiovascular progenitors (2016) (0)
- Faculty Opinions recommendation of Self-Organized Synchronous Calcium Transients in a Cultured Human Neural Network Derived from Cerebral Organoids. (2019) (0)
- Growth factors and their receptors in human teratocarcinoma (1989) (0)
- Endoglin haploinsufficency in endothelial cells from Rendu-Osler-Weber patient derived induced pluripotent stem cells leads to upregulation of MTUS1 gene expression (2015) (0)
- Executive summary of the 12th HHT international scientific conference (2017) (0)
- Chapter 13 – Differentiation in Early Development (2009) (0)
- Human induced pluripotent stem cell-derived endothelial cells in thrombosis-on-a-chip devices (2018) (0)
- EGF , epithelium and Early differentiation and the TGF β superfamily 693 (1999) (0)
- Multiplexed fluidic circuit board for controlled perfusion of 3D blood vessels-on-a-chip (2022) (0)
- A Novel Approach for the Pure Isolation of Ventricular Cardiomyocytes from human Embryonic Stem Cells: a dual MYL2-T2A-mCherry NKX2-5-eGFP Fluorescent Reporter Line (2016) (0)
- Direct Cardiomyocyte Reprogramming : A New Direction for Subject Collection The Biology of Heart Disease Genetics and Disease of Ventricular Muscle (2013) (0)
- Pluripotent Stem Cell Models of a Cardiac Sodium Channelopathy (2012) (0)
- The days of molecular medicine: San Diego 13-17 March 2002. (2002) (0)
- Adult stem cells: generation of self-organizing mini-organs in a dish (2021) (0)
- F1000Prime recommendation of Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial. (2013) (0)
- Origins and types of stem cells (2021) (0)
- Toward Human Models of Cardiorenal Syndrome in vitro (2022) (0)
- Stem Cell Repor ts BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells (2016) (0)
- Pseudomyogenic Hemangioendothelioma Recapitulated in Endothelial Cells from Human Induced Pluripotent Stem Cells Engineered to Express the SERPINE1-FOSB Translocation (2019) (0)
- Epidermal growth factor-receptor interaction in rat pheochromocytoma (PC12) and human epidermoid A431 cells: biochemical and ultrastructural studies. (1984) (0)
- Differenciation directe de cardiomyocytes a partir de cellules souches embryonnaires humaines (2006) (0)
- O▪99 Making cardiomyocytes from embryonic and adult stem cells (2005) (0)
- Avian as a model for human ovarian cancer: advantages reviewed (2016) (0)
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