Christine Orengo
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Professor of Bioinformatics
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Christine Orengobiology Degrees
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Biology
Christine Orengo's Degrees
- Bachelors Biochemistry University of Manchester
Why Is Christine Orengo Influential?
(Suggest an Edit or Addition)According to Wikipedia, Christine Anne Orengo is a Professor of Bioinformatics at University College London known for her work on protein structure, particularly the CATH database. Orengo serves as president of the International Society for Computational Biology , the first woman to do so in the history of the society.
Christine Orengo's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- CATH--a hierarchic classification of protein domain structures. (1997) (2556)
- InterPro: the integrative protein signature database (2008) (1850)
- InterPro in 2017—beyond protein family and domain annotations (2016) (1217)
- The InterPro protein families database: the classification resource after 15 years (2014) (1186)
- InterPro in 2019: improving coverage, classification and access to protein sequence annotations (2018) (1101)
- InterPro in 2011: new developments in the family and domain prediction database (2011) (1100)
- The InterPro protein families and domains database: 20 years on (2020) (858)
- A large-scale evaluation of computational protein function prediction (2013) (784)
- Protein structure alignment. (1989) (718)
- Protein superfamilles and domain superfolds (1994) (699)
- Evolution of function in protein superfamilies, from a structural perspective. (2001) (687)
- One fold with many functions: the evolutionary relationships between TIM barrel families based on their sequences, structures and functions. (2002) (600)
- New developments in the InterPro database (2007) (542)
- Predicting protein function from sequence and structure (2007) (521)
- Microarray analysis after RNA amplification can detect pronounced differences in gene expression using limma (2006) (488)
- Transient protein-protein interactions: structural, functional, and network properties. (2010) (454)
- CATH: comprehensive structural and functional annotations for genome sequences (2014) (423)
- SSAP: sequential structure alignment program for protein structure comparison. (1996) (337)
- Functional impairment in COPD patients: the impact of anxiety and depression. (2000) (323)
- CATH: an expanded resource to predict protein function through structure and sequence (2016) (322)
- An expanded evaluation of protein function prediction methods shows an improvement in accuracy (2016) (316)
- Protein families and their evolution-a structural perspective. (2005) (314)
- The CATH domain structure database: new protocols and classification levels give a more comprehensive resource for exploring evolution (2006) (306)
- The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis (2004) (273)
- The CATH database: an extended protein family resource for structural and functional genomics (2003) (256)
- Identification and classification of protein fold families. (1993) (224)
- From protein structure to function. (1999) (224)
- New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures (2012) (222)
- The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens (2019) (219)
- From Structure to Function (2021) (214)
- A rapid method of protein structure alignment. (1990) (210)
- Protein folds and functions. (1998) (208)
- The CATH classification revisited—architectures reviewed and new ways to characterize structural divergence in superfamilies (2008) (208)
- The Pain in Neuropathy Study (PiNS): a cross-sectional observational study determining the somatosensory phenotype of painful and painless diabetic neuropathy (2016) (206)
- From structure to function: Approaches and limitations (2000) (205)
- Low‐Density Lipoprotein Receptor Gene Familial Hypercholesterolemia Variant Database: Update and Pathological Assessment (2012) (204)
- One session cognitive behavioural therapy for elderly patients with chronic obstructive pulmonary disease (2001) (204)
- Assigning genomic sequences to CATH (2000) (199)
- Protein function annotation by homology-based inference (2009) (197)
- Protein folds, functions and evolution. (1999) (173)
- The CATH Database provides insights into protein structure/function relationships (1999) (172)
- Plasticity of enzyme active sites. (2002) (168)
- ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data (2012) (156)
- Consensus clustering and functional interpretation of gene-expression data (2004) (154)
- Fast structure alignment for protein databank searching (1992) (146)
- Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes. (2013) (146)
- CATH: increased structural coverage of functional space (2020) (145)
- Quantifying the similarities within fold space. (2002) (145)
- Extending CATH: increasing coverage of the protein structure universe and linking structure with function (2010) (145)
- Stability-activity tradeoffs constrain the adaptive evolution of RubisCO (2014) (137)
- Inferring Function Using Patterns of Native Disorder in Proteins (2007) (137)
- Progress of structural genomics initiatives: an analysis of solved target structures. (2005) (136)
- PSI-2: structural genomics to cover protein domain family space. (2009) (135)
- Multiple protein structure alignment (1994) (134)
- Sequence and structural differences between enzyme and nonenzyme homologs. (2002) (133)
- Alpha plus beta folds revisited: some favoured motifs. (1993) (128)
- Evolution of protein function, from a structural perspective. (1999) (125)
- Protein function prediction--the power of multiplicity. (2009) (121)
- Protein Superfamily Evolution and the Last Universal Common Ancestor (LUCA) (2006) (112)
- Protein domain superfolds and superfamilies (1994) (110)
- Structural diversity of domain superfamilies in the CATH database. (2006) (108)
- Exploring the structure and function paradigm. (2008) (106)
- CATH: expanding the horizons of structure-based functional annotations for genome sequences (2018) (106)
- CATHEDRAL: A Fast and Effective Algorithm to Predict Folds and Domain Boundaries from Multidomain Protein Structures (2007) (105)
- Identification of new herpesvirus gene homologs in the human genome. (2002) (105)
- Evolution of protein superfamilies and bacterial genome size. (2004) (101)
- The CATH protein family database: A resource for structural and functional annotation of genomes (2002) (99)
- CXCL5 Mediates UVB Irradiation–Induced Pain (2011) (97)
- Trimethylaminuria and a human FMO3 mutation database (2003) (97)
- Recognizing the fold of a protein structure (2003) (94)
- Gene3D: a domain-based resource for comparative genomics, functional annotation and protein network analysis (2011) (94)
- Progress towards mapping the universe of protein folds (2004) (91)
- The use of risperidone for psychosis and agitation in demented patients with Parkinson's disease. (1997) (89)
- The CATH domain structure database. (2005) (89)
- Domain-based and family-specific sequence identity thresholds increase the levels of reliable protein function transfer. (2009) (88)
- Genomewide function conservation and phylogeny in the Herpesviridae. (2001) (88)
- Classification of protein folds (1994) (87)
- Sensory, psychological, and metabolic dysfunction in HIV-associated peripheral neuropathy: A cross-sectional deep profiling study (2014) (83)
- LigASite—a database of biologically relevant binding sites in proteins with known apo-structures (2007) (83)
- Comparison of dorsal root ganglion gene expression in rat models of traumatic and HIV-associated neuropathic pain (2009) (82)
- Safety and Efficacy of Testosterone Gel 1% Augmentation in Depressed Men With Partial Response to Antidepressant Therapy (2005) (81)
- Gene3D: comprehensive structural and functional annotation of genomes (2007) (81)
- Correlation of observed fold frequency with the occurrence of local structural motifs. (1999) (81)
- Towards fully automated structure-based function prediction in structural genomics: a case study. (2007) (80)
- A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat (2014) (80)
- Gene3D: structural assignment for whole genes and genomes using the CATH domain structure database. (2002) (79)
- Exploring the Evolution of Novel Enzyme Functions within Structurally Defined Protein Superfamilies (2012) (79)
- Structural genomics is the largest contributor of novel structural leverage (2009) (76)
- Analysis of domain structural class using an automated class assignment protocol. (1996) (75)
- Bioinformatics: Genes, Proteins and Computers (2007) (73)
- Yeast cytochrome c oxidase: a model system to study mitochondrial forms of the haem-copper oxidase superfamily. (2012) (73)
- InterPro in 2022 (2022) (73)
- Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination (2013) (73)
- A holistic approach to protein structure alignment. (1989) (72)
- CORA—Topological fingerprints for protein structural families (2008) (72)
- Accuracy of Self‐Reported Depression in Persons with Dementia (2005) (71)
- Gene3D: Extensive prediction of globular domains in proteins (2017) (70)
- Gene3D: modelling protein structure, function and evolution (2005) (69)
- Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use (2016) (69)
- Functional classification of CATH superfamilies: a domain-based approach for protein function annotation (2015) (66)
- A rapid classification protocol for the CATH Domain Database to support structural genomics (2001) (66)
- Gene3D: Extensive prediction of globular domains in proteins (2017) (65)
- Microeconomic Principles Explain an Optimal Genome Size in Bacteria (2004) (64)
- PDBe-KB: a community-driven resource for structural and functional annotations (2019) (63)
- FFPred: an integrated feature-based function prediction server for vertebrate proteomes (2008) (62)
- GeMMA: functional subfamily classification within superfamilies of predicted protein structural domains (2009) (62)
- Protein function prediction using domain families (2013) (62)
- Gene3D: merging structure and function for a Thousand genomes (2009) (61)
- Genome3D: a UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains (2012) (61)
- Comprehensive genome analysis of 203 genomes provides structural genomics with new insights into protein family space (2006) (61)
- A local alignment method for protein structure motifs. (1993) (60)
- Gene3D: expanding the utility of domain assignments (2015) (60)
- A Protein Structure Comparison Methodology (1996) (59)
- Gene3D: Multi-domain annotations for protein sequence and comparative genome analysis (2013) (59)
- Outcome of a workshop on archiving structural models of biological macromolecules. (2006) (59)
- The efficacy and tolerability of divalproex sodium in elderly demented patients with behavioral disturbances (1998) (59)
- Emerging concepts in pseudoenzyme classification, evolution, and signaling (2019) (59)
- The CATH extended protein‐family database: Providing structural annotations for genome sequences (2002) (58)
- The CATH Hierarchy Revisited—Structural Divergence in Domain Superfamilies and the Continuity of Fold Space (2009) (57)
- VarSite: Disease variants and protein structure (2019) (56)
- Recurring structural motifs in proteins with different functions (1993) (56)
- Recurrent mutations in SARS-CoV-2 genomes isolated from mink point to rapid host-adaptation (2020) (55)
- Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint (2007) (54)
- Predicting Protein Function with Hierarchical Phylogenetic Profiles: The Gene3D Phylo-Tuner Method Applied to Eukaryotic Genomes (2007) (54)
- Combining sensitive database searches with multiple intermediates to detect distant homologues. (1999) (53)
- Large-Scale Analysis Exploring Evolution of Catalytic Machineries and Mechanisms in Enzyme Superfamilies (2016) (50)
- Review: what can structural classifications reveal about protein evolution? (2001) (50)
- Contemporary approaches to protein structure classification (1998) (49)
- A fast and automated solution for accurately resolving protein domain architectures (2010) (49)
- Protein CoAlation and antioxidant function of coenzyme A in prokaryotic cells (2018) (49)
- Comparing, Contrasting and Combining Clusters in Viral Gene Expression (2001) (47)
- Functional classification of CATH superfamilies: a domain-based approach for protein function annotation (2015) (47)
- CATH FunFHMMer web server: protein functional annotations using functional family assignments (2015) (47)
- Genome-Wide Transcriptional Profiling of Skin and Dorsal Root Ganglia after Ultraviolet-B-Induced Inflammation (2014) (46)
- Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation (2014) (46)
- Genome3D: exploiting structure to help users understand their sequences (2014) (45)
- FLORA: A Novel Method to Predict Protein Function from Structure in Diverse Superfamilies (2009) (44)
- VIDA: a virus database system for the organization of animal virus genome open reading frames (2001) (44)
- An overview of comparative modelling and resources dedicated to large-scale modelling of genome sequences (2017) (44)
- Functional innovation from changes in protein domains and their combinations. (2016) (43)
- FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies (2011) (43)
- Dementia Deficits Scale: Rating Self-Awareness of Deficits (2004) (42)
- Clinical and ethical implications of impaired executive control functions for patient autonomy. (2000) (42)
- Identification and distribution of protein families in 120 completed genomes using Gene3D (2005) (41)
- Rigid-body Ligand Recognition Drives Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Receptor Triggering (2010) (39)
- Systematic computational prediction of protein interaction networks (2011) (39)
- Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury (2018) (39)
- Diversity in protein domain superfamilies (2015) (38)
- Genome analysis: Assigning protein coding regions to three‐dimensional structures (2008) (38)
- PainNetworks: A web-based resource for the visualisation of pain-related genes in the context of their network associations (2013) (37)
- Methods of remote homology detection can be combined to increase coverage by 10% in the midnight zone (2007) (36)
- Understanding enzyme function evolution from a computational perspective. (2017) (36)
- Transmission of SARS-CoV-2 from humans to animals and potential host adaptation (2022) (36)
- Classifying a protein in the CATH database of domain structures. (1998) (36)
- Cancer‐associated mutations are preferentially distributed in protein kinase functional sites (2009) (35)
- Exploiting structural classifications for function prediction: towards a domain grammar for protein function. (2009) (35)
- Structural and Functional View of Polypharmacology (2016) (32)
- Do testosterone levels relate to aggression in elderly men with dementia? (2002) (32)
- Functional site plasticity in domain superfamilies☆ (2013) (32)
- Protein function annotation using protein domain family resources. (2016) (31)
- Target selection for structural genomics: an overview. (2008) (31)
- Protein Structure Comparison (2002) (30)
- Contribution of psychosis and depression to behavioral disturbances in geropsychiatric inpatients with dementia. (1999) (30)
- Target Selection and Determination of Function in Structural Genomics (2003) (29)
- Laser Stark and optical-optical double resonance studies of some molecules used in optically pumped submillimetre lasers (1978) (28)
- Novel Computational Protocols for Functionally Classifying and Characterising Serine Beta-Lactamases (2016) (28)
- The history of the CATH structural classification of protein domains (2015) (28)
- Protein folds: towards understanding folding from inspection of native structures. (1995) (28)
- Assessing strategies for improved superfamily recognition (2005) (27)
- Contrastive learning on protein embeddings enlightens midnight zone (2021) (27)
- Behavioral Disturbances in Geropsychiatric Inpatients Across Dementia Types (2000) (27)
- Detailed analysis of function divergence in a large and diverse domain superfamily: toward a refined protocol of function classification. (2010) (27)
- Gene3D: structural assignments for the biologist and bioinformaticist alike (2003) (27)
- Stress induces remodelling of yeast interaction and co-expression networks. (2013) (26)
- CATH-Gene3D: Generation of the Resource and Its Use in Obtaining Structural and Functional Annotations for Protein Sequences. (2017) (26)
- Crystal structures of the human Dysferlin inner DysF domain (2014) (26)
- Male depression: a review of gender concerns and testosterone therapy. (2004) (25)
- Contribution of PTSD/POW history to behavioral disturbances in dementia (2001) (25)
- The Benefits of Psychiatric Hospitalization for Older Nursing Home Residents (1996) (25)
- Finding the “Dark Matter” in Human and Yeast Protein Network Prediction and Modelling (2010) (25)
- Aggression in Individuals Newly Diagnosed With Dementia (2008) (24)
- Exploiting protein structure data to explore the evolution of protein function and biological complexity (2006) (24)
- Positive Selection during the Evolution of the Blood Coagulation Factors in the Context of Their Disease-Causing Mutations (2014) (24)
- Comparative evolutionary analysis of protein complexes in E. coli and yeast (2010) (24)
- Systems biology approaches to finding novel pain mediators (2013) (24)
- Factors Affecting Deficit Awareness in Persons with Dementia (2005) (23)
- The Gene3D Web Services: a platform for identifying, annotating and comparing structural domains in protein sequences (2011) (23)
- Rehospitalization of older psychiatric inpatients: an investigation of predictors. (1999) (23)
- Recurrence of a binding motif? (1993) (23)
- A framework for modelling virus gene expression data (2002) (22)
- PDBe-KB: collaboratively defining the biological context of structural data (2021) (22)
- Survey of current protein family databases and their application in comparative, structural and functional genomics. (2005) (22)
- Evolutionary history of the TBP-domain superfamily (2013) (22)
- ISPIDER Central: an integrated database web-server for proteomics (2008) (21)
- The impact of structural bioinformatics tools and resources on SARS-CoV-2 research and therapeutic strategies (2020) (21)
- A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations (2018) (20)
- Interactions between estrogen and EGF in uterine growth and function. (1987) (20)
- Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips (2007) (20)
- Determinants of Behavioral Symptoms in Dementia Patients (2003) (20)
- Functioning in Rheumatoid Arthritis (2001) (19)
- Characterization of pathogenic germline mutations in human Protein Kinases (2011) (19)
- Clustering FunFams using sequence embeddings improves EC purity (2021) (19)
- Tolerability and effectiveness of atypical antipsychotics in male geriatric inpatients (2001) (18)
- Nonalcohol-Related Use Disorders in Geropsychiatric Patients (2000) (17)
- AlphaFold2 reveals commonalities and novelties in protein structure space for 21 model organisms (2022) (17)
- A structural perspective on genome evolution. (2003) (16)
- The use and tolerability of fluoxetine in geropsychiatric inpatients. (1996) (16)
- PFDB: a generic protein family database integrating the CATH domain structure database with sequence based protein family resources (2002) (16)
- Correlation of testosterone with aggression in demented elderly men. (1997) (16)
- Cross‐cultural differences in demented geropsychiatric inpatients with behavioral disturbances (1999) (16)
- Genome-wide RNA-Sequencing analysis identifies a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery (2017) (16)
- A structural perspective on genome evolution (2004) (16)
- A practical and robust sequence search strategy for structural genomics target selection (2004) (15)
- Metagenome Mining: A Sequence Directed Strategy for the Retrieval of Enzymes for Biocatalysis (2016) (15)
- CATH functional families predict functional sites in proteins (2020) (15)
- CODA: Accurate Detection of Functional Associations between Proteins in Eukaryotic Genomes Using Domain Fusion (2010) (14)
- Gene Function Prediction from Functional Association Networks Using Kernel Partial Least Squares Regression (2015) (14)
- InterPro in 2011: new developments in the family and domain prediction database (2012) (14)
- Association of Serum Cholesterol and Triglyceride Levels with Agitation and Cognitive Function in a Geropsychiatry Unit (1996) (13)
- Using CATH‐Gene3D to Analyze the Sequence, Structure, and Function of Proteins (2015) (13)
- An integrated approach to the interpretation of Single Amino Acid Polymorphisms within the framework of CATH and Gene3D (2009) (13)
- Macromolecular structure information and databases (1996) (13)
- The Classification of Protein Domains. (2017) (13)
- FunFam protein families improve residue level molecular function prediction (2019) (13)
- 1,000 structures and more from the MCSG (2011) (13)
- Proteome Data Integration: Characteristics and Challenges (2005) (12)
- TOLERABILITY OF CLONAZEPAM IN DEMENTED AND NON‐DEMENTED GEROPSYCHIATRIC PATIENTS (1997) (12)
- ISCB’s initial reaction to New England Journal of Medicine editorial on data sharing (2016) (11)
- The Kinetics of the Reactions of Low Spin Ferric Haem Undecapeptide with Hydrogen Peroxide (1981) (11)
- Uncovering the Molecular Machinery of the Human Spindle—An Integration of Wet and Dry Systems Biology (2012) (11)
- Genome3D: integrating a collaborative data pipeline to expand the depth and breadth of consensus protein structure annotation (2019) (11)
- Outcomes of decreased length of hospital stay among geriatric patients with dementia. (2001) (11)
- Identifying and characterising key alternative splicing events in Drosophila development (2015) (11)
- Unique signalling connectivity of FGFR3-TACC3 oncoprotein revealed by quantitative phosphoproteomics and differential network analysis (2017) (11)
- DOMPLOT: a program to generate schematic diagrams of the structural domain organization within proteins, annotated by ligand contacts. (1999) (10)
- Computational approaches to predict protein functional families and functional sites. (2021) (10)
- A Review of Methods for Protein Structure Comparison (1992) (10)
- Contribution of cognitive impairment, depression, and psychosis to the outcome of agitated geropsychiatric inpatients with dementia. (1998) (10)
- FUN-L: gene prioritization for RNAi screens (2015) (10)
- ISCB’s Initial Reaction to The New England Journal of Medicine Editorial on Data Sharing (2016) (10)
- Characterizing and explaining the impact of disease-associated mutations in proteins without known structures or structural homologs (2022) (9)
- The contribution of cognitive impairment, medical burden, and psychopathology to the functional status of geriatric psychiatric inpatients. (1998) (9)
- Extensive prediction of globular domains in proteins. (2017) (9)
- Analysis of temporal transcription expression profiles reveal links between protein function and developmental stages of Drosophila melanogaster (2017) (9)
- A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) (2020) (9)
- Arthropod Ectoparasites Have Potential to Bind SARS-CoV-2 via ACE (2021) (8)
- Regulation of the uterine epidermal growth factor receptor by estrogen. (1990) (8)
- Protein Families: Relating Protein Sequence, Structure, and Function (2014) (8)
- Metagenomic ene-reductases for the bioreduction of sterically challenging enones (2019) (8)
- Evolution of Protein Domains (2007) (8)
- Cluster Based Integration of Heterogeneous Biological Databases Using the AutoMed Toolkit (2005) (8)
- Function Diversity Within Folds and Superfamilies (2009) (8)
- Biological impact of mutually exclusive exon switching (2021) (8)
- A Framework for Modelling Short, High-Dimensional Multivariate Time Series: Preliminary Results in Virus Gene Expression Data Analysis (2001) (8)
- ENFIN--A European network for integrative systems biology. (2009) (8)
- Exploring Enzyme Evolution from Changes in Sequence, Structure, and Function. (2018) (7)
- Assessment of protein domain fusions in human protein interaction networks prediction: application to the human kinetochore model. (2010) (7)
- Insertions in the SARS-CoV-2 Spike N-Terminal Domain May Aid COVID-19 Transmission (2021) (7)
- CATHe: detection of remote homologues for CATH superfamilies using embeddings from protein language models (2022) (7)
- Outcome of Psychiatric Hospitalization for Very Low-Functioning Demented Patients (1997) (7)
- Protein folds and their recognition from sequence (1996) (7)
- Psychosis in geropsychiatric inpatients with and without dementia (1996) (7)
- Exploring Structure – Function Relationships in Moonlighting Proteins (2017) (6)
- Genomic insights into evolution. (2002) (6)
- Delirium in Geropsychiatric Patients: Patient Characteristics and Treatment Outcomes (1997) (6)
- Depression in male geropsychiatric inpatients with and without dementia: a naturalistic study. (1997) (6)
- Use of structure comparison methods for the refinement of protein structure predictions. I. Identifying the structural family of a protein from low‐resolution models (2002) (6)
- EyeSite: a semi-automated database of protein families in the eye (2004) (6)
- The classification of protein domains. (2008) (5)
- Transcriptional Profiling of Dendritic Cells in a Mouse Model of Food‐Antigen‐Induced Anaphylaxis Reveals the Upregulation of Multiple Immune‐Related Pathways (2019) (5)
- Comparison of Drosophila melanogaster Embryo and Adult Proteome by SWATH-MS Reveals Differential Regulation of Protein Synthesis, Degradation Machinery, and Metabolism Modules. (2019) (5)
- Measuring aggression in older adults: A latent variable modeling approach (2002) (5)
- Dynamic changes in the brain protein interaction network correlates with progression of Aβ42 pathology in Drosophila (2018) (5)
- Assigning protein function from domain-function associations using DomFun (2020) (5)
- Co-Expression Network Models Suggest that Stress Increases Tolerance to Mutations (2015) (4)
- Association of a culturally defined syndrome (nervios) with chest pain and DSM-IV affective disorders in Hispanic patients referred for cardiac stress testing. (2004) (4)
- Agitation in dementia of the Alzheimer's type on a geropsychiatric inpatient unit (1996) (4)
- Tracing Evolution Through Protein Structures: Nature Captured in a Few Thousand Folds (2021) (4)
- Cognitive decline in patients on an acute geropsychiatric unit. (1998) (4)
- The Protein Chart (2008) (4)
- The evolution of protein functions and networks: a family-centric approach. (2009) (4)
- BioMap: gene family based integration of heterogeneous biological databases using AutoMed metadata (2004) (4)
- Coordination of structural bioinformatics activities across Europe (2018) (3)
- Novel machine learning approaches revolutionize protein knowledge. (2022) (3)
- Estrogen Regulation of Uterine Epidermal Growth Factor Receptor and Nuclear Proto-Oncogenes (1991) (3)
- Guardianship applications for elderly patients: why do they fail? (2000) (3)
- Estrogen Regulation of Protooncogene Expression (1992) (3)
- Shared structural motif in proteins (1993) (3)
- A roadmap for the functional annotation of protein families: a community perspective (2022) (3)
- Choosing the Best Enzyme Complex Structure Made Easy. (2018) (3)
- Sequence Comparison Methods (2002) (3)
- Classifying a Protein Fold in the CATH Hierarchic Database (1998) (3)
- Characterizing disease-associated human proteins without available protein structures or homologues (2021) (3)
- Exploiting Protein Structures to Predict Protein Functions (2011) (3)
- Exploiting protein family and protein network data to identify novel drug targets for bladder cancer (2022) (2)
- Associating Protein Domains with Biological Functions: A Tripartite Network Approach (2019) (2)
- The Genome3D Consortium for Structural Annotations of Selected Model Organisms. (2020) (2)
- ModelCIF: An extension of PDBx/mmCIF data representation for computed structure models (2022) (2)
- 3D-Beacons: decreasing the gap between protein sequences and structures through a federated network of protein structure data resources (2022) (2)
- Macromolecular structure information and databases. The EU BRIDGE Database Project Consortium. (1996) (2)
- Structure comparison and protein structure classifications (2005) (2)
- Placement Predictors of Geropsychiatric Inpatients (1998) (2)
- Growth Factor, Oncogene, and Steroidal Interactions in the Regulation of Uterine Growth and Function (1989) (2)
- Corrigendum to “Progress of Structural Genomics Initiatives: An Analysis of Solved Target Structures” [J. Mol. Biol. (2005) 348, 1235–1260] (2005) (2)
- A multidisciplinary ethics teaching conference on a geropsychiatric service. (1999) (2)
- Regulation of EGF Receptors and Nuclear Protooncogenes by Estrogen (1989) (2)
- The Protein Structure Initiative (2010) (2)
- Androgen Replacement: Sexual Behavior, Affect, and Cognition (2003) (1)
- Domain Family Analyses to Understand Protein Function Evolution (2010) (1)
- Discharge Plans from a Geropsychiatric Unit (2000) (1)
- Abstracts from the ninth annual meeting of the molecular graphics societyApplications of dynamic programming to protein structure (1990) (1)
- PLOS Computational Biology 2017 Reviewer and Editorial Board Thank You (2018) (1)
- Interactions of Estrogens, Protooncogenes and Growth Factors (1991) (1)
- The opportunities and challenges posed by the new generation of deep learning-based protein structure predictors. (2023) (1)
- Insights into protein evolution and function from the CATH structural database (2001) (1)
- Protein domain assignments (1999) (1)
- Classification of protein structures (2008) (1)
- Protein structure classifications (2003) (1)
- Progress towards recognising protein folds from amino acid sequence (1993) (1)
- Protein Structure Classification (2015) (1)
- Srinivasan (1962–2021) in Bioinformatics and beyond (2022) (1)
- Profiling the Site of Protein CoAlation and Coenzyme A Stabilization Interactions (2022) (1)
- KinFams: De-Novo Classification of Protein Kinases Using CATH Functional Units (2023) (1)
- Chapter 1. Target selection in structural genomics projects to increase knowledge of protein structure and function space. (2008) (1)
- Classifying Proteins into Domain Structure Families (2013) (1)
- Target selection for structural genomics of infectious diseases. (2014) (1)
- Structural insights into multi-protein communication systems. (2012) (1)
- CATH functional families predict protein functional sites (2020) (1)
- A Domain-Based Machine Learning Approach for Function Prediction using CATH FunFams (2017) (0)
- The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens (2019) (0)
- Functional Metagenome Mining : A sequence directed strategy for the retrieval of functional enzymes for biocatalysis * * (2016) (0)
- Software Tools for Protein Structure Analysis and Fold Classification (1999) (0)
- Three-dimensional Structure Databases of Biological Macromolecules. (2022) (0)
- Broad functional profiling of fission yeast proteins using phenomics and machine learning (2023) (0)
- BIROn - Birkbeck Institutional Research Online reveal between (2021) (0)
- Structure of inner DysF domain of human dysferlin (2014) (0)
- Genome Analysis: Assigning Protein Coding Regions to 3D Structures (1998) (0)
- Comprar The Protein Chart | Christine A. Orengo | 9783527319633 | Wiley (2007) (0)
- Enzymes: evolution of function from a structural perspective (2002) (0)
- PROTEIN FOLD FAMILIES AND STRUCTURAL MOTIFS (1994) (0)
- Structural and Functional View of Polypharmacology (2017) (0)
- Structure Comparisons Beyond the Experimental Realm: Paving the Way for Higher Quality Structure Predictions (2001) (0)
- GOBLET: achievements and goals a year on (2014) (0)
- Protein motifs and folding recognition (1994) (0)
- Editorial overview: Genomic insights into evolution (2002) (0)
- Update and analysis of the ucl pro-protein convertase subtilisin / kexin type9 gene (pcsk9) variant database. (2014) (0)
- Mapping the Constrained Coding Regions in the Human Genome to Their Corresponding Proteins (2022) (0)
- Letter by the ISCB President (2021) (0)
- A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations (2019) (0)
- Chapter 3 Protein fold topology and structural families (1997) (0)
- Faculty Opinions recommendation of Protein metamorphosis: the two-state behavior of Mad2. (2009) (0)
- Genome-wide RNA-Sequencing analysis reveals a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery (2017) (0)
- Identify discriminating features to predict functional sites in enzyme structures (2013) (0)
- Faculty Opinions recommendation of Structural proteomics of minimal organisms: conservation of protein fold usage and evolutionary implications. (2006) (0)
- Improved Robustness in Time Series Analysis of Gene Expression Data by Polynomial Model Based Clustering (2006) (0)
- Expanding Genome3D with models for human proteins from SWISS-MODEL (2019) (0)
- Protein‐fold classification (2012) (0)
- FunFam protein families improve residue level molecular function prediction (2019) (0)
- Unique monocyte transcriptomic profiles are associated with preclinical atherosclerosis in women with systemic lupus erythematosus (SLE) (2020) (0)
- Amplification of RNA results in predictable changes in gene representation in microarray studies (2004) (0)
- Structure—3D Classification (2004) (0)
- Genome-wide RNA-Sequencing analysis identifies a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery (2017) (0)
- Exploring the use of CATH-Gene3D functional families in comparative modelling (2015) (0)
- Expanding Genome3D with 3D-models from SWISS-MODEL (2019) (0)
- Genius: System for Assigning Protein Coding Regions to 3D Structures (1999) (0)
- Protein function prediction using domain families (2013) (0)
- The Interaction Between Pathogens and the Host (2015) (0)
- Using CATH-Gene3D to explore the impacts of disease-associated genetic variations (2016) (0)
- A Structural Perspective on Genome Evolution(Invited Talk) (2003) (0)
- Identifying and characterising key alternative splicing events in Drosophila development (2015) (0)
- Structural Annotations of Genomes with Superfamily and G3D (2013) (0)
- Assessing Strategies For Improved Superfamily Recognition in Genome Annotation (2005) (0)
- Structural Comparison of Proteins (2004) (0)
- ISCB’s initial reaction to New England Journal of Medicine editorial on data sharing (2016) (0)
- Faculty Opinions recommendation of Defining the fold space of membrane proteins: the CAMPS database. (2006) (0)
- Faculty Opinions recommendation of A normalised scale for structural genomics target ranking: the OB-Score. (2006) (0)
- PROTEIN FAMILIES WILEY SERIES ON PROTEIN AND PEPTIDE SCIENCE (2013) (0)
- [Invited Lecture] Protein Folds and Functions (1998) (0)
- ISMB/ECCB 2017 PROCEEDINGS PAPERS COMMITTEE. (2017) (0)
- Dissecting peripheral protein-membrane interfaces (2022) (0)
- Integrating Genome3D structural annotations and predicted secondary structures in InterPro 7 (2019) (0)
- Protein folds and motifs: representation, comparison and classification (2006) (0)
- Assessing functional novelty of PSI structures via structure-function analysis of large and diverse superfamilies (2008) (0)
- Protein structure and function analyses to understand the implication of mutually exclusive splicing (2018) (0)
- Faculty Opinions recommendation of A gold standard set of mechanistically diverse enzyme superfamilies. (2007) (0)
- Integrating wet and dry systems biology to detect novel genes associated with the mitotic spindle (2010) (0)
- Ismb/eccb 2017 Proceedings Papers Committee (2017) (0)
- Functional Insights from Structural Families (2000) (0)
- CATH FunFams for domain boundary recogntion and template selection (2018) (0)
- Dynamic changes in the brain protein 1 interaction network correlates with 2 progression of Aβ42 pathology in 3 Drosophila 4 (2019) (0)
- Structural and energetic analyses of SARS-CoV-2 N-terminal domain characterise sugar binding pockets and suggest putative impacts of variants on COVID-19 transmission (2022) (0)
- Assigning protein function from domain-function associations using DomFun (2022) (0)
- The CATH domain structure database (2005) (0)
- Characterizing domain-specific open educational resources by linking ISCB Communities of Special Interest to Wikipedia (2022) (0)
- Editorial overview: Sequences and topology: sequences, structures, genomes and populations. (2014) (0)
- Faculty Opinions recommendation of Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction. (2010) (0)
- Chapter 6 Function Diversity Within Folds and Superfamilies (0)
- Functional Diversity of the HUP Domain Superfamily (2013) (0)
- Comparative and structural genomics to explore the evolution of protein function (2007) (0)
- Assessing Protein Function Through Structural Similarities with CATH. (2020) (0)
- Estrogen induced desensitization of c -{\it fos\/} messenger RNA expression {\it in vivo\/} (1991) (0)
- The Dementia Rating Scale-Initiation/Perseveration Subtest in MMSE-Intact Demented Patients (2000) (0)
- AXONAL NEUREGULIN-1 IS RATE LIMITING BUT NOT ESSENTIAL FOR PERIPHERAL NERVE REMYELINATION (2013) (0)
- Tracking dynamic changes in Alzheimer’s disease brain proteome reveals ageing-independent damage in Drosophila (2018) (0)
- Gene3D and Understanding Proteome Evolution (2007) (0)
- THE KINETICS OF THE REACTIONS OF LOW SPIN FERRIC HEME UNDECAPEPTIDE WITH HYDROGEN PEROXIDE (1982) (0)
- VariPred: Enhancing Pathogenicity Prediction of Missense Variants Using Protein Language Models (2023) (0)
- Editorial overview: Catalysis and regulation. (2017) (0)
- ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data (2012) (0)
- Genius : An Automated System for Assigning Genome ORFs to 3 D Structures , Using a Novel Multiple Intermediate Sequence Search (2000) (0)
- Protein structures: their validation fold classification and interactions (1996) (0)
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