Christoph Bock
#45,433
Most Influential Person Now
Principal Investigator and Visiting Professor at the Medical University of Vienna
Why Is Christoph Bock Influential?
(Suggest an Edit or Addition)According to Wikipedia, Christoph Bock is a German bioinformatician and principal investigator at the Research Center for Molecular Medicine of the Austrian Academy of Sciences and a visiting professor at the Medical University of Vienna.
Christoph Bock's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Somatic mutations of calreticulin in myeloproliferative neoplasms. (2013) (1693)
- Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals (2010) (1025)
- Dnmt3a is essential for hematopoietic stem cell differentiation (2011) (949)
- Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines (2011) (947)
- Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications (2010) (673)
- Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling (2011) (622)
- BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing (2005) (596)
- Pooled CRISPR screening with single-cell transcriptome read-out (2016) (573)
- Specification of tissue-resident macrophages during organogenesis (2016) (562)
- Quantitative comparison of genome-wide DNA methylation mapping technologies. (2010) (558)
- Toward understanding and exploiting tumor heterogeneity (2015) (557)
- Analysing and interpreting DNA methylation data (2012) (548)
- Comprehensive Analysis of DNA Methylation Data with RnBeads (2014) (546)
- Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. (2014) (494)
- DNA methylation signatures link prenatal famine exposure to growth and metabolism (2014) (476)
- Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging. (2013) (391)
- Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types (2011) (381)
- Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk (2012) (364)
- The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (2016) (360)
- A DNA methylation fingerprint of 1628 human samples. (2011) (359)
- Single-Cell DNA Methylome Sequencing and Bioinformatic Inference of Epigenomic Cell-State Dynamics (2015) (345)
- DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. (2012) (344)
- ChIPmentation: fast, robust, low-input ChIP-seq for histones and transcription factors (2015) (342)
- Recommendations for the design and analysis of epigenome-wide association studies (2013) (336)
- BLUEPRINT to decode the epigenetic signature written in blood (2012) (320)
- Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution (2010) (319)
- Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes (2016) (314)
- Erosion of dosage compensation impacts human iPSC disease modeling. (2012) (306)
- LOLA: enrichment analysis for genomic region sets and regulatory elements in R and Bioconductor (2015) (305)
- Spatiotemporal structure of cell fate decisions in murine neural crest (2019) (271)
- Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity (2017) (261)
- Quantitative comparison of DNA methylation assays for biomarker development and clinical applications (2016) (251)
- A prognostic DNA methylation signature for stage I non-small-cell lung cancer. (2013) (236)
- A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis (2013) (236)
- CpG Island Methylation in Human Lymphocytes Is Highly Correlated with DNA Sequence, Repeats, and Predicted DNA Structure (2006) (227)
- LONGITUDINAL MOLECULAR TRAJECTORIES OF DIFFUSE GLIOMA IN ADULTS (2019) (223)
- Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis. (2007) (213)
- Structural cells are key regulators of organ-specific immune response (2020) (207)
- CpG Island Mapping by Epigenome Prediction (2007) (205)
- Making sense of big data in health research: Towards an EU action plan (2016) (205)
- Whole-exome sequencing identifies novel MPL and JAK2 mutations in triple-negative myeloproliferative neoplasms. (2015) (201)
- High-throughput bisulfite sequencing in mammalian genomes. (2009) (201)
- Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells (2020) (199)
- Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia (2015) (194)
- Single‐cell transcriptomes reveal characteristic features of human pancreatic islet cell types (2015) (192)
- Computational epigenetics (2008) (186)
- Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2 (2020) (185)
- B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma (2018) (183)
- DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation (2016) (183)
- The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space (2017) (172)
- DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma (2017) (171)
- Epigenome Mapping Reveals Distinct Modes of Gene Regulation and Widespread Enhancer Reprogramming by the Oncogenic Fusion Protein EWS-FLI1 (2015) (165)
- RnBeads 2.0: comprehensive analysis of DNA methylation data (2019) (164)
- Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020 (2020) (163)
- Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion (2020) (161)
- DNA Methylation Analysis of Chromosome 21 Gene Promoters at Single Base Pair and Single Allele Resolution (2009) (160)
- HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response (2019) (153)
- Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections. (2015) (151)
- Global DNA Demethylation During Mouse Erythropoiesis in Vivo (2011) (148)
- DNA methylation biomarkers in cancer: progress towards clinical implementation (2012) (144)
- Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping (2008) (143)
- Managing drug resistance in cancer: lessons from HIV therapy (2012) (143)
- Mitochondria Are a Subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells. (2019) (136)
- Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci. (2011) (130)
- Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks (2016) (128)
- Rational discovery of molecular glue degraders via scalable chemical profiling (2020) (125)
- Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation (2020) (125)
- BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing (2011) (123)
- Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells (2017) (118)
- Multi-Omics of Single Cells: Strategies and Applications (2016) (118)
- Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time (2016) (108)
- Epigenetic biomarker development. (2009) (107)
- High-Resolution Mapping of H1 Linker Histone Variants in Embryonic Stem Cells (2013) (105)
- On Low-Dimensional Solvmanifolds (2009) (105)
- Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection (2019) (103)
- SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses (2021) (102)
- A reversible gene trap collection empowers haploid genetics in human cells (2013) (102)
- A promoter DNA demethylation landscape of human hematopoietic differentiation (2011) (102)
- Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium (2018) (102)
- Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF (2020) (97)
- Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression (2017) (96)
- RRBSMAP: a fast, accurate and user-friendly alignment tool for reduced representation bisulfite sequencing (2012) (94)
- KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia (2015) (93)
- Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature (2011) (90)
- EpiExplorer: live exploration and global analysis of large epigenomic datasets (2012) (88)
- Dnmt 3 a is essential for hematopoietic stem cell differentiation (2013) (87)
- LifeTime and improving European healthcare through cell-based interceptive medicine (2020) (87)
- Promoter Hypermethylation of the Phosphatase DUSP22 Mediates PKA-Dependent TAU Phosphorylation and CREB Activation in Alzheimer's Disease (2014) (85)
- Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells (2019) (81)
- Molecular design of hypothalamus development (2020) (79)
- Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency. (2019) (75)
- Systematic characterization of BAF mutations provides insights into intra-complex synthetic lethalities in human cancers (2019) (73)
- Ultra-high-throughput single-cell RNA sequencing and perturbation screening with combinatorial fluidic indexing (2021) (73)
- Single-cell transcriptomics combined with interstitial fluid proteomics defines cell-type-specific immune regulation in atopic dermatitis. (2020) (72)
- An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion (2018) (72)
- Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues (2012) (71)
- The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis–relapse samples of precursor B-cell acute lymphoblastic leukemia (2012) (70)
- Dissecting the role of aberrant DNA methylation in human leukemia (2015) (68)
- Notch inhibition allows oncogene independent generation of iPS cells (2014) (67)
- Selective Mediator-dependence of cell type-specifying transcription (2020) (63)
- Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a. (2014) (62)
- The Organoid Cell Atlas (2020) (62)
- EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data (2009) (60)
- DeepBlue epigenomic data server: programmatic data retrieval and analysis of epigenome region sets (2016) (60)
- Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden (2021) (58)
- Structural conservation versus functional divergence of maternally expressed microRNAs in the Dlk1/Gtl2 imprinting region (2008) (57)
- High-content CRISPR screening (2022) (56)
- Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL (2020) (56)
- Glioma progression is shaped by genetic evolution and microenvironment interactions (2022) (56)
- Circadian rhythm influences induction of trained immunity by BCG vaccination. (2020) (55)
- Acute BAF perturbation causes immediate changes in chromatin accessibility (2021) (54)
- Next-generation sequencing identifies major DNA methylation changes during progression of Ph+ chronic myeloid leukemia (2016) (52)
- Chromatin accessibility profiling methods (2021) (51)
- STAT5BN642H is a driver mutation for T cell neoplasia (2017) (51)
- Genome-wide mapping of DNA methylation: a quantitative technology comparison (2010) (50)
- Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells (2018) (50)
- Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species (2018) (48)
- MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation (2019) (47)
- The Human Genomic Melting Map (2007) (47)
- Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma (2020) (46)
- Mutational Landscape of the Transcriptome Offers Putative Targets for Immunotherapy of Myeloproliferative Neoplasms. (2019) (46)
- Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis (2021) (46)
- Guadecitabine Plus Ipilimumab in Unresectable Melanoma: The NIBIT-M4 Clinical Trial (2019) (45)
- Knowledge-primed neural networks enable biologically interpretable deep learning on single-cell sequencing data (2019) (45)
- Single-Cell RNA-seq Analysis Reveals a Crucial Role for Collagen Triple Helix Repeat Containing 1 (CTHRC1) Cardiac Fibroblasts after Myocardial Infarction. (2020) (45)
- Functional Analysis of a Potassium-Chloride Co-Transporter 3 (SLC12A6) Promoter Polymorphism Leading to an Additional DNA Methylation Site (2008) (45)
- Emergence of coronavirus disease 2019 (COVID-19) in Austria (2020) (42)
- Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice (2017) (40)
- Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia (2016) (39)
- The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease (2018) (39)
- NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation (2014) (39)
- Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host disease (2020) (38)
- Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk. (2016) (38)
- Persistence of mature dendritic cells, TH2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4Rα blockade (2021) (37)
- Influence of ground predators and water levels on Lapwing Vanellus vanellus breeding success in two continental wetlands (2008) (36)
- A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis. (2018) (35)
- Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-Free and Overall Survival Times for Patients With Locoregional Cancer. (2016) (34)
- Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring (2018) (34)
- RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy (2020) (34)
- A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis (2016) (33)
- Epigenomics and Single-cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis. (2019) (33)
- Viral variant-resolved wastewater surveillance of SARS-CoV-2 at national scale. (2022) (33)
- A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor. (2017) (33)
- VCF.Filter: interactive prioritization of disease-linked genetic variants from sequencing data (2017) (32)
- Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL (2019) (32)
- Colocalization analyses of genomic elements: approaches, recommendations and challenges (2018) (32)
- Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets (2020) (32)
- Quantitative comparison of within-sample heterogeneity scores for DNA methylation data (2020) (30)
- Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes (2019) (30)
- Differential DNA Methylation Analysis without a Reference Genome (2015) (30)
- Single-cell analysis reveals innate lymphoid cell lineage infidelity in atopic dermatitis (2021) (29)
- The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity (2020) (28)
- Relationship between genome and epigenome - challenges and requirements for future research (2014) (28)
- Identification of Novel Imprinted Differentially Methylated Regions by Global Analysis of Human-Parthenogenetic-Induced Pluripotent Stem Cells (2013) (28)
- Ultra-high throughput single-cell RNA sequencing by combinatorial fluidic indexing (2019) (27)
- MethMarker: user-friendly design and optimization of gene-specific DNA methylation assays (2009) (27)
- A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN. (2016) (26)
- STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway (2020) (26)
- Temporal dissection of an enhancer cluster reveals distinct temporal and functional contributions of individual elements. (2021) (26)
- A discrete subset of epigenetically primed human NK cells mediates antigen-specific immune responses (2020) (25)
- Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors (2014) (24)
- BiQ Analyzer HiMod: an interactive software tool for high-throughput locus-specific analysis of 5-methylcytosine and its oxidized derivatives (2014) (23)
- CDK6 coordinates JAK2 V617F mutant MPN via NF-κB and apoptotic networks. (2019) (23)
- Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia (2017) (20)
- Proposed Terminology and Classification of Pre-Malignant Neoplastic Conditions: A Consensus Proposal☆ (2017) (20)
- Peptide translocation by the lysosomal ABC transporter TAPL is regulated by coupling efficiency and activation energy (2019) (19)
- Cell-Type Specificity of Genomic Imprinting in Cerebral Cortex (2020) (19)
- Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation (2020) (19)
- Life-long epigenetic programming of cortical architecture by maternal ‘Western’ diet during pregnancy (2019) (19)
- Assembly of the MHC I peptide-loading complex determined by a conserved ionic lock-switch (2015) (19)
- Diagenode® Premium RRBS technology: cost-effective DNA methylation mapping with superior coverage (2016) (18)
- Familial early-onset dementia with complex neuropathologic phenotype and genomic background (2016) (18)
- Distributed changes of the functional connectome in patients with glioblastoma (2020) (16)
- Coloc-stats: a unified web interface to perform colocalization analysis of genomic features (2018) (16)
- MIRA: an R package for DNA methylation-based inference of regulatory activity (2018) (15)
- Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3 (2021) (15)
- Human resident memory T cells exit the skin and mediate systemic Th2-driven inflammation (2021) (14)
- αβγδ T cells play a vital role in fetal human skin development and immunity (2021) (14)
- Web-based analysis of (Epi-) genome data using EpiGRAPH and Galaxy. (2010) (14)
- Structural cells are key regulators of organ-specific immune responses (2020) (14)
- An extended combinatorial 15N, 13Cα, and $$ ^{13} {\text{C}}^{\prime } $$13C′ labeling approach to protein backbone resonance assignment (2015) (14)
- DNA methylation QTL analysis identifies new regulators of human longevity (2020) (13)
- Complex Patterns of Chromosome 11 Aberrations in Myeloid Malignancies Target CBL, MLL, DDB1 and LMO2 (2013) (13)
- Recommendations for the Transition to Open Access in Austria (2015) (13)
- Spontaneously Resolved Atopic Dermatitis Shows Melanocyte and Immune Cell Activation Distinct From Healthy Control Skin (2021) (12)
- Corrigendum: DNA methylation signatures link prenatal famine exposure to growth and metabolism (2015) (12)
- Erratum to: Making sense of big data in health research: towards an EU action plan (2016) (12)
- Time-shared experiments for efficient assignment of triple-selectively labeled proteins. (2014) (12)
- High-Resolution Mapping of H 1 Linker Histone Variants in Embryonic Stem Cells (2014) (12)
- Mutational dynamics and transmission properties of SARS-CoV-2 superspreading events in Austria (2020) (11)
- Lysosomal targeting of the ABC transporter TAPL is determined by membrane-localized charged residues (2019) (11)
- The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells. (2019) (11)
- Parallel reverse genetic screening in mutant human cells using transcriptomics (2016) (11)
- Tumor mutational burden and immune infiltrates in renal cell carcinoma and matched brain metastases (2021) (11)
- Targeted mutation screening of 292 candidate genes in 38 children with inborn haematological cytopenias efficiently identifies novel disease‐causing mutations (2018) (10)
- Emergence of SARS-CoV-2 Alpha lineage and its correlation with quantitative wastewater-based epidemiology data (2022) (10)
- NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity (2019) (9)
- Notch-mediated expansion of cord blood progenitors: maintenance of transcriptional and epigenetic fidelity (2015) (9)
- CpG island methylation in human lymphocytes is highly correlated with DNA sequence patterns, repeat frequencies and predicted DNA structure (2005) (9)
- NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells (2020) (9)
- Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells (2019) (8)
- Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets (2022) (8)
- STAT 5 B N 642 H is a driver mutation for T cell neoplasia (2018) (8)
- Anti-apoptotic molecule BCL2 is a therapeutic target in steroid-refractory graft-versus-host disease. (2020) (8)
- SARS-CoV-2 escapes CD8 T cell surveillance via mutations in MHC-I restricted epitopes (2020) (8)
- Curation and expansion of Human Phenotype Ontology for defined groups of inborn errors of immunity (2021) (7)
- Life‐long impairment of glucose homeostasis upon prenatal exposure to psychostimulants (2019) (7)
- Conformational stabilization of the membrane embedded targeting domain of the lysosomal peptide transporter TAPL for solution NMR (2013) (7)
- Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (2021) (7)
- Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL (2018) (7)
- Improving reference epigenome catalogs by computational prediction (2015) (7)
- Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern (2015) (7)
- DeepBlueR: large-scale epigenomic analysis in R (2017) (7)
- Inference of tumor cell-specific transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection of cancer (2018) (6)
- Response to comment on “Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2” (2021) (6)
- Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia (2019) (6)
- Preserve personal freedom in networked societies (2016) (6)
- Tegwondo: Development of a novel near-continuous dose-dense temozolomide regimen for the treatment of recurrent brain tumors (2008) (6)
- A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation (2022) (5)
- Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions (2021) (5)
- Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes (2020) (5)
- Frequent Mutations in the Calreticulin Gene CALR in Myeloproliferative Neoplasms (2013) (5)
- Team work at its best – TAPL and its two domains (2015) (5)
- Rapid neutrophil mobilization by VCAM-1+ endothelial cell-derived extracellular vesicles (2022) (5)
- PD‐L1 overexpression correlates with JAK2‐V617F mutational burden and is associated with 9p uniparental disomy in myeloproliferative neoplasms (2022) (5)
- DNAMethylation Dynamics of Human Hematopoietic Stem Cell Differentiation (2017) (5)
- DeepBlue: Epigenomic Data Server (2014) (4)
- High-throughput Mutational Surveillance of the SARS-CoV-2 Spike Gene (2021) (4)
- Histone deacetylase 1 controls CD4+ T cell trafficking in autoinflammatory diseases. (2021) (4)
- Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor (2021) (4)
- The Organoid Cell Atlas: A Rosetta Stone for Biomedical Discovery and Regenerative Therapy (2020) (4)
- Geography of non-formal symplectic and contact manifolds (2008) (4)
- Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers (2019) (4)
- Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species (2022) (3)
- Hematopoietic expression of a chimeric murine‐human CALR oncoprotein allows the assessment of anti‐CALR antibody immunotherapies in vivo (2021) (3)
- Complex Interplay Between MAZR and Runx3 Regulates the Generation of Cytotoxic T Lymphocyte and Memory T Cells (2021) (3)
- An extended combinatorial 15 N, 13 C a , and 13 C 0 labeling approach to protein backbone resonance assignment (2015) (3)
- Comparative analysis of neutrophil and monocyte epigenomes (2017) (3)
- Cellular stress in brain organoids is limited to a distinct and bioinformatically removable subpopulation (2022) (3)
- Synergy and competition between cancer genome sequencing and epigenome mapping projects (2014) (3)
- Epigenome-based prediction of gene expression across species (2018) (3)
- Structural characterization of the intrinsically disordered domain of Mycobacterium tuberculosis protein tyrosine kinase A (2018) (3)
- Mutational Landscape of the Transcriptome Offers a Rich Neoantigen Resource for Immunotherapy of Myeloproliferative Neoplasms (2018) (3)
- An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation (2021) (3)
- Comprehensive Analysis of Nasal Polyps Reveals a More Pronounced Type 2 Transcriptomic Profile of Epithelial Cells and Mast Cells in Aspirin-Exacerbated Respiratory Disease (2022) (3)
- DNA methylation: a matter of culture (2013) (3)
- Hepatitis C virus-induced epigenetic and transcriptional changes persist post cure (2017) (3)
- Analyzing epigenome data in context of genome evolution and human diseases. (2012) (3)
- TECPR2 a positive regulator of autophagy is implicated in healthy brain ageing (2017) (2)
- Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK–driven lymphomagenesis (2020) (2)
- Model-Based Whole-Genome Analysis of DNA Methylation Fidelity (2015) (2)
- Overexpression of PD-L1 Correlates with JAK2-V617F Mutational Burden and Is Associated with Chromosome 9p Uniparental Disomy in MPN (2020) (2)
- Rapid, early and accurate SARS-CoV-2 detection using RT-qPCR in primary care: a prospective cohort study (REAP-1) (2021) (2)
- STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pigmentation pathway (2018) (2)
- Regulation of DNAMethylation Patterns by CK 2-Mediated Phosphorylation of Dnmt 3 a (2017) (2)
- Chromatin accessibility maps of chronic lymphocytic leukemia identify subtype-specific epigenome signatures and associated transcription regulatory networks (2016) (2)
- Stress signaling boosts interferon-induced gene transcription in macrophages (2022) (2)
- 161 Single-cell RNA sequencing combined with interstitial fluid proteomics defines cell-type-specific immune gene regulation in atopic dermatitis (2020) (2)
- Abstract CT059: Epigenetic tumor remodelling to improve the efficacy of immune checkpoint blockade: the NIBIT-M4 clinical trial (2018) (2)
- The Gene Regulation Knowledge Commons: The action area of GREEKC. (2021) (2)
- On Formality and Solvmanifolds (2008) (2)
- High-throughput drug screening identifies the ATR-CHK1 pathway as a therapeutic vulnerability of CALR mutated hematopoietic cells (2021) (1)
- Whole Exome Sequencing Reveals Clonal Evolution of Myeloproliferative Neoplasms to Acute Myeloid Leukemia (2015) (1)
- Single-cell RNA-seq analysis reveals the crucial role of Collagen Triplex Helix Repeat Containing 1 (CTHRC1) cardiac fibroblasts for ventricular remodeling after myocardial infarction (2019) (1)
- The Western Australian Alliance to End Homelessness Outcomes Measurement and Evaluation Framework - Ending Homelessness in Western Australia: A Complexity Science Approach to Measurement, Evaluation and Accountability (2019) (1)
- Detailed temporal dissection of an enhancer cluster reveals two distinct roles for individual elements (2020) (1)
- Computational epigenetics : bioinformatic methods for epigenome prediction, DNA methylation mapping and cancer epigenetics (2008) (1)
- Publisher Correction: Rational discovery of molecular glue degraders via scalable chemical profiling (2021) (1)
- EpiExplorer: live exploration and global analysis of large epigenomic datasets (2012) (1)
- ENDOTHELIAL CELL-DERIVED EXTRACELLULAR VESICLES ELICIT NEUTROPHIL DEPLOYMENT FROM THE SPLEEN FOLLOWING ACUTE MYOCARDIAL INFARCTION (2020) (1)
- Acknowledging and citing core facilities (2022) (1)
- Homelessness and COVID-19: CSI response (2020) (1)
- A Diabetes-induced innate immune memory drives inflammation and atherosclerosis, despite restoration of normoglycaemia (2018) (1)
- Near-continuous temozolomide and low-dose weekly CCNU: A novel chemotherapy regimen with activity in malignant gliomas resistant to dose-dense temozolomide alone. (2010) (1)
- Informing Resource Allocation for Investment in Early Childhood: A Review of the International Peer‐Reviewed Evidence (2022) (1)
- Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes (2022) (1)
- Synergy and competition between cancer genome sequencing and epigenome mapping projects (2014) (1)
- Mutational and inflammatory microenvironment characteristics in primary and matched local recurrent non-small cell lung cancer brain metastases. (2018) (1)
- EpiGRAPHregression: A toolkit for (epi-)genomic correlation analysis and prediction of quantitative attributes (2006) (1)
- Novel imprints in mouse blastocysts are predominantly DNA methylation independent (2020) (1)
- Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors (2014) (1)
- Interleukin‐6 initiates muscle‐ and adipose tissue wasting in a novel C57BL/6 model of cancer‐associated cachexia (2022) (1)
- LifeTime and improving European healthcare through cell-based interceptive medicine (2020) (1)
- A DNA methylation fingerprint of 1 , 628 human samples Material (2011) (1)
- Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species (2018) (1)
- DeepBlueR: Large-scale Epigenomic Analysis in R ; {DeepBlueR}: {L}arge-scale Epigenomic Analysis in {R} (2017) (1)
- SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression. (2022) (1)
- Relationship between genome and epigenome - challenges and requirements for future research (2014) (1)
- Rechallenge of malignant gliomas with Temozolomide – can it be effective? (2007) (1)
- Safety and immunobiological activity of guadecitabine sequenced with ipilimumab in metastatic melanoma patients: The phase Ib NIBIT-M4 study. (2019) (0)
- Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets (2020) (0)
- MTHFD1 is a genetic interactor of BRD4 and links folate metabolism to transcriptional regulation (2018) (0)
- B cells sustain inflammation and improve survival in human melanoma (2018) (0)
- Machine learning enables data-driven reconstruction of the hematopoietic lineage Authors (2017) (0)
- THE DIAGENODE EPIGENETICS CUSTOM SERVICE: Complete workflows for genome-scale DNA methylation and histone marks analysis (2016) (0)
- Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL (2020) (0)
- Radiomic Features Define Risk and Are Linked to DNA Methylation Attributes in Primary CNS Lymphoma (2022) (0)
- Erratum to: Making sense of big data in health research: towards an EU action plan (2016) (0)
- Selective Mediator dependence of cell-type-specifying transcription (2020) (0)
- Cell Stem Cell Resource DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation (2016) (0)
- Long-term skin resident memory T cells proliferate clonally and contribute to inflammation in human graft-versus-host disease (2020) (0)
- Making sense of big data in health research: Towards an EU action plan (2016) (0)
- Genome Wide DNA Methylation and Transcriptome Analysis in HSC Aging (2011) (0)
- Extreme phenotypes define epigenetic and metabolic signatures in cardiometabolic syndrome. (2020) (0)
- Publisher Correction: Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection (2020) (0)
- EPCO-15. LINKING HISTOLOGICAL GLIOBLASTOMA PHENOTYPES TO TRANSCRIPTIONAL SUBTYPES AND PROGNOSIS USING DEEP LEARNING (2022) (0)
- RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy (2020) (0)
- Epigenetic regulation of T cell lineages in skin and blood following hematopoietic stem cell transplantation. (2023) (0)
- Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation (2023) (0)
- Recruitment of the MLL complex via specific interaction of the p30 variant of C/EBPα with Wdr5 is essential for development of acute myeloid leukemia (2013) (0)
- LIQUORICE: detection of epigenetic signatures in liquid biopsies based on whole-genome sequencing data (2022) (0)
- Conformational stabilization of the membrane embedded targeting domain of the lysosomal peptide transporter TAPL for solution NMR (2013) (0)
- Next Generation Sequencing Identifies DNA Methylation Patterns Indicative of Disease Progression in Ph+ CML (2014) (0)
- Glioma Through the Looking GLASS: the Glioma Longitudinal Analysis consortium, molecular evolution of diffuse gliomas (2017) (0)
- Tumour mutational burden and immune infiltrates in primary renal cell carcinoma and matched brain metastases (2019) (0)
- Analysis and Prediction of Helix Shift Errors in Homology Modeling (2006) (0)
- Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL (2018) (0)
- The Organoid Cell Atlas (2020) (0)
- Towards Comparative Epigenomics: A Software Toolkit For Cross-Species Epigenome Data Analysis (2008) (0)
- 659 Persistence of mature dendritic cells, Th2A and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4R-alpha blockade (2021) (0)
- Single-cell transcriptomics reveals unique features of human pancreatic islet cell subtypes (2015) (0)
- Comprehensive approach for identification of functional FCGR2C alleles resulting in protein expression as a determinant for predicting predisposition to autoimmunity (2021) (0)
- On rational homotopy and minimal models (2019) (0)
- Tegwondo – development of a novel near-continuous dose-dense temozolomide regimen for the treatment of recurrent gliomas (2008) (0)
- The solution on the geography-problem of non-formal compact (almost) contact manifolds (2021) (0)
- On five-dimensional contact solvmanifolds (2021) (0)
- IVF: stars may have to consider the risk of stolen parenthood (2008) (0)
- 354 Innate lymphoid cells in healthy and atopic skin (2020) (0)
- DRES-05. MOLECULAR EVOLUTION OF DIFFUSE GLIOMAS AND THE GLIOMA LONGITUDINAL ANALYSIS CONSORTIUM (2018) (0)
- Hybrid gas generator with temporary gas generation reactor (2008) (0)
- A comparison of two computer algorithms for emulating a vector graphics environment on a dot matrix printer : an honors thesis [(HONRS 499)] (1989) (0)
- Towards a solution on the geography-problem of non-formal compact contact manifolds (2021) (0)
- The Western Australian Alliance to End Homelessness Outcomes Measurement and Evaluation Framework: Data Dictionary [RE-RELEASED] (2020) (0)
- The Western Australian Alliance to End Homelessness - Ending Homelessness in Western Australia Report 2019 (2019) (0)
- The Western Australian Alliance to End Homelessness outcomes measurement framework: dashboard (2019) (0)
- Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia (2017) (0)
- COVID-19 and mental health: CSI response (2020) (0)
- The Western Australian Alliance to End Homelessness outcomes measurement framework: data dictionary (2019) (0)
- The Western Australian Alliance to End Homelessness Outcomes Measurement and Evaluation Framework: Data Dictionary (2019) (0)
- The stepping stone approach towards the Genetics Clinic of the Future (2014) (0)
- The Western Australian Alliance to End Homelessness - Ending Homelessness in Western Australia Report 2019 [RE-RELEASED] (2020) (0)
- Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion (2020) (0)
- Multipotent Progenitors Instruct Ontogeny of the Superior Colliculus (2023) (0)
- Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring (2018) (0)
- Targeting the catalytic activity of HDAC1 in T cells protects against experimental autoimmune encephalomyelitis (2023) (0)
- PL01.3.A Radiomic features and DNA methylation attributes in primary CNS lymphoma (2022) (0)
- Integrated Multi-omics Analyses of NFKB1 patients B cells points towards an up regulation of NF-κB network inhibitors (2022) (0)
- Publisher Correction: Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection (2020) (0)
- Abstract PR13: DNA methylation mapping and computational modeling in a large Ewing sarcoma cohort identifies principles of tumor heterogeneity and their impact on clinical phenotypes (2016) (0)
- Epigenome characterization of CHO cells in response to evolutionary pressures and over time (2016) (0)
- Toward high-throughput functional epigenomics using CRISPR single-cell sequencing (2017) (0)
- Establishment of tissue-resident macrophage core and tissue specific programs during embryogenesis (2016) (0)
- Integrated ATAC-Seq and Chemosensitivity Profiling Identifies Rational Drug Combinations in Ibrutinib-Treated CLL Patients (2017) (0)
- RnBeads 2.0: comprehensive analysis of DNA methylation data (2019) (0)
- Erratum: Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia. (2015) (0)
- An ERK-Dependent Feedb ack Mechanism Prevents Hematopoietic Stem Cell Exhaustion Graphical (2018) (0)
- FRI0055 Histone deacetylase 1 (HDAC1): a novel therapeutic target in rheumatoid arthritis (2017) (0)
- Parallel reverse genetic screening in mutant human cells using transcriptomics (2016) (0)
- Abstract LB-325: Developmental hierarchy in Langerhans cell histiocytosis (2019) (0)
- The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space (2018) (0)
- Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (2021) (0)
- An Exhaustive Methode for CpG Island Annotation (2009) (0)
- Colonization of developing tissues by EMP-derived macrophage precursors (2016) (0)
- MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation (2019) (0)
- Nuclear receptor corepressor 1 controls regulatory T cell subset differentiation and effector function (2022) (0)
- Cellular Reprogramming Erases Aberrant DNA Methylation and the Malignant Phenotype in Chronic Myeloid Leukemia (2014) (0)
- STAT5 Gain-of-Function Variants Promote Precursor T-Cell Receptor Activation to Drive T-Cell Acute Lymphoblastic Leukemia (2022) (0)
- 033 Expansion of BCL2+ lymphocytes in cutaneous graft-versus host disease is associated with steroid resistance and poor prognosis (2019) (0)
- Modern Epigenomics DNA Methylomics (2012) (0)
- Author response: Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression (2017) (0)
- Abstract B69: Epigenomics and single-cell sequencing define a developmental hierarchy in Langerhans cell histiocytosis (2020) (0)
- Abstract 319: Integrated ATAC-seq and single-cell synergistic chemosensitivity profiling identifies rational drug combinations in ibrutinib treated CLL patients (2019) (0)
- Requirement of DNMT1 to orchestrate epigenomic reprogramming during NPM-ALK driven T cell lymphomagenesis (2020) (0)
- Molecular design of hypothalamus development (2020) (0)
- The 2000HIV study: Design, multi-omics methods and participant characteristics (2022) (0)
- Abstract A60: An epigenetic map of Ewing sarcoma revealed by comprehensive epigenome sequencing (2014) (0)
- Knowledge-primed neural networks enable biologically interpretable deep learning on single-cell sequencing data (2020) (0)
- Longitudinal molecular trajectories of diffuse glioma in adults (2019) (0)
- Predicting microRNA target sites using a combined target gene prediction approach (2008) (0)
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