Christopher Thiemermann

Christopher Thiemermann's AcademicInfluence.com Rankings

Chemistry

#1938

World Rank

#2761

Historical Rank

Organic Chemistry

#265

World Rank

#323

Historical Rank

chemistry Degrees

Christopher Thiemermann

Biology

#5572

World Rank

#8084

Historical Rank

Biochemistry

#674

World Rank

#773

Historical Rank

biology Degrees

Download Badge

Chemistry
Biology

Christopher Thiemermann's Degrees

PhD Biochemistry University of California, Berkeley
Masters Chemistry Stanford University
Bachelors Chemistry Stanford University

Why Is Christopher Thiemermann Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Christopher Thiemermann's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. (1993) (1596)
Mesenchymal Stromal Cells: Current Understanding and Clinical Status (2009) (879)
Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo. (1990) (548)
Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase. (1994) (424)
Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion. (2004) (424)
Nitric oxide‐mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock (1993) (415)
The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure. (1995) (393)
Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide. (1993) (361)
Ligands of the peroxisome proliferator‐activated receptors (PPAR‐γ and PPAR‐α) reduce myocardial infarct size (2002) (354)
Definition and drivers of acute traumatic coagulopathy: clinical and experimental investigations (2010) (336)
Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. (2000) (329)
Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin (2008) (308)
Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle. (1997) (304)
Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion. (2006) (300)
Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity (1995) (288)
ANTI-APOPTOTIC AND ANTI-INFLAMMATORY EFFECTS OF HYDROGEN SULFIDE IN A RAT MODEL OF REGIONAL MYOCARDIAL I/R (2009) (256)
Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury. (2002) (253)
Mechanism of Gram-positive Shock: Identification of Peptidoglycan and Lipoteichoic Acid Moieties Essential in the Induction of Nitric Oxide Synthase, Shock, and Multiple Organ Failure (1998) (249)
On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies (2003) (244)
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation. (2004) (235)
Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase. (2007) (232)
The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase (1995) (226)
The role of the L-arginine: nitric oxide pathway in circulatory shock. (1994) (226)
Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock (1995) (225)
Peptidoglycan and Lipoteichoic Acid from Staphylococcus aureus Induce Tumor Necrosis Factor Alpha, Interleukin 6 (IL-6), and IL-10 Production in Both T Cells and Monocytes in a Human Whole Blood Model (2000) (222)
Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo. (2004) (220)
Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo. (1994) (214)
Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation (2002) (212)
Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock (1993) (202)
Nitric oxide and septic shock. (1997) (199)
Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia (2005) (195)
Beneficial effects of PPAR-γ ligands in ischemia–reperfusion injury, inflammation and shock (2005) (192)
Endothelial cells metabolize NG-monomethyl-L-arginine to L-citrulline and subsequently to L-arginine. (1990) (191)
High-Density Lipoproteins in Sepsis and Septic Shock: Metabolism, Actions, and Therapeutic Applications (2004) (186)
INVITED OPINION: ROLE OF NITRIC OXIDE IN HEMORRHAGIC, TRAUMATIC, AND ANAPHYLACTIC SHOCK AND THERMAL INJURY (1994) (186)
THE PRODUCTION OF HYDROGEN SULFIDE LIMITS MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY AND CONTRIBUTES TO THE CARDIOPROTECTIVE EFFECTS OF PRECONDITIONING WITH ENDOTOXIN, BUT NOT ISCHEMIA IN THE RAT (2006) (183)
Lipoproteins in inflammation and sepsis. I. Basic science (2006) (177)
Endogenous Interleukin-6 Enhances the Renal Injury, Dysfunction, and Inflammation Caused by Ischemia/Reperfusion (2005) (176)
ERYTHROPOIETIN ATTENUATES THE TISSUE INJURY ASSOCIATED WITH HEMORRHAGIC SHOCK AND MYOCARDIAL ISCHEMIA (2004) (168)
Generation of endogenous hydrogen sulfide by cystathionine γ-lyase limits renal ischemia/reperfusion injury and dysfunction (2008) (162)
GSK-3β inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat* (2005) (158)
Agonists of Peroxisome-Proliferator Activated Receptor-Gamma Reduce Renal Ischemia/Reperfusion Injury (2003) (156)
Trauma alarmins as activators of damage‐induced inflammation (2012) (156)
Peptidoglycan and Lipoteichoic Acid in Gram-Positive Bacterial Sepsis: Receptors, Signal Transduction, Biological Effects, and Synergism (2003) (154)
Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide. (1993) (150)
Effect of rosiglitazone and 15-deoxy-Δ12,14-prostaglandin J2 on bleomycin-induced lung injury (2005) (147)
GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury. (2003) (145)
Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. (1995) (145)
The Septic Heart: Current Understanding of Molecular Mechanisms and Clinical Implications (2019) (144)
Endothelin-1 stimulates the biosynthesis of tumour necrosis factor in macrophages: ET-receptors, signal transduction and inhibition by dexamethasone. (1997) (140)
Potential therapeutic effect of antioxidant therapy in shock and inflammation. (2004) (137)
Mediation via different receptors of the vasoconstrictor effects of endothelins and sarafotoxins in the systemic circulation and renal vasculature of the anaesthetized rat (1993) (136)
Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: Effects of the PPAR-α agonist WY14643 (2006) (132)
Abandon the Mouse Research Ship? Not Just Yet! (2014) (131)
SELECTIVE INHIBITION OF THE ACTIVITY OF INDUCIBLE NITRIC OXIDE SYNTHASE PREVENTS THE CIRCULATORY FAILURE, BUT NOT THE ORGAN INJURY/DYSFUNCTION, CAUSED BY ENDOTOXIN (1998) (128)
Role of IL-6 in the pleurisy and lung injury caused by carrageenan. (1999) (128)
Calpain inhibitor-1 reduces renal ischemia/reperfusion injury in the rat. (2001) (126)
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation. (2002) (124)
Relaxin activates the L-arginine-nitric oxide pathway in vascular smooth muscle cells in culture. (1998) (121)
Dexamethasone ameliorates renal ischemia-reperfusion injury. (2009) (120)
Effect of calpain inhibitor I, an inhibitor of the proteolysis of IκB, on the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat (1997) (119)
Regulation of the expression of the inducible isoform of nitric oxide synthase. (1995) (118)
Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions (2021) (117)
Beneficial effects of PPAR-gamma ligands in ischemia-reperfusion injury, inflammation and shock. (2005) (116)
Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy (2017) (116)
Calpain inhibitor I reduces the activation of nuclear factor‐κΒ and organ injury/dysfunction in hemorrhagic shock (2001) (115)
Recombinant human erythropoietin protects the liver from hepatic ischemia‐reperfusion injury in the rat (2006) (115)
Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat: a possible role for protein tyrosine kinase (1997) (115)
GLYCOGEN SYNTHASE KINASE 3&bgr; AS A TARGET FOR THE THERAPY OF SHOCK AND INFLAMMATION (2007) (113)
Endogenous endothelium-derived relaxing factor opposes hypoxic pulmonary vasoconstriction and supports blood flow to hypoxic alveoli in anesthetized rabbits. (1992) (113)
Reconstituted High-Density Lipoprotein Attenuates Organ Injury and Adhesion Molecule Expression in a Rodent Model of Endotoxic Shock (2003) (112)
Attenuation of endotoxin‐induced multiple organ dysfunction by 1‐amino‐2‐hydroxy‐guanidine, a potent inhibitor of inducible nitric oxide synthase (1996) (112)
Tempol reduces infarct size in rodent models of regional myocardial ischemia and reperfusion. (1999) (111)
Role of Induced Nitric Oxide in the Initiation of the Inflammatory Response After Postischemic Injury (2002) (111)
Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase‐3β (2006) (107)
Inhibitors of poly (ADP‐ribose) synthetase reduce renal ischemia‐reperfusion injury in the anesthetized rat in vivo (2000) (106)
Effects of 5‐aminoisoquinolinone, a water‐soluble, potent inhibitor of the activity of poly (ADP‐ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock (2000) (106)
Role of nitric oxide in the circulatory failure and organ injury in a rodent model of Gram‐positive shock (1996) (104)
Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. (2004) (104)
Rosiglitazone and 15‐deoxy‐Δ12,14‐prostaglandin J2, ligands of the peroxisome proliferator‐activated receptor‐γ (PPAR‐γ), reduce ischaemia/reperfusion injury of the gut (2003) (104)
The involvement of endothelium‐derived relaxing factor in the regulation of renal cortical blood flow in the rat (1991) (103)
Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14. (2002) (103)
Membrane-permeable radical scavengers (tempol) for shock, ischemia-reperfusion injury, and inflammation (2003) (103)
Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis (2014) (103)
Pioglitazone improves lipid and insulin levels in overweight rats on a high cholesterol and fructose diet by decreasing hepatic inflammation (2010) (101)
Reduction in the evolution of murine type II collagen-induced arthritis by treatment with rosiglitazone, a ligand of the peroxisome proliferator-activated receptor gamma. (2003) (101)
Comparison of the induction of cyclooxygenase and nitric oxide synthase by endotoxin in endothelial cells and macrophages. (1995) (100)
The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities (2014) (99)
The cyclopentenone prostaglandin 15‐deoxy‐Δ12,14‐ PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat (2003) (97)
Analysis of the signal transduction in the induction of nitric oxide synthase by lipoteichoic acid in macrophages (1996) (96)
A cell wall component from pathogenic and non-pathogenic gram-positive bacteria (peptidoglycan) synergises with endotoxin to cause the release of tumour necrosis factor-alpha, nitric oxide production, shock, and multiple organ injury/dysfunction in the rat. (2001) (96)
Glycogen synthase kinase-3beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse. (2006) (95)
Involvement of tyrosine kinase in the induction of cyclo‐oxygenase and nitric oxide synthase by endotoxin in cultured cells (1994) (93)
Support of renal blood flow after ischaemic‐reperfusion injury by endogenous formation of nitric oxide and of cyclo‐oxygenase vasodilator metabolites (1993) (92)
Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury (2000) (90)
Prevention of the expression of inducible nitric oxide synthase by aminoguanidine or aminoethyl-isothiourea in macrophages and in the rat. (1996) (90)
Glycogen synthase kinase-3beta inhibition attenuates asthma in mice. (2007) (90)
Cytokine‐mediated induction of cyclo‐oxygenase‐2 by activation of tyrosine kinase in bovine endothelial cells stimulated by bacterial lipopolysaccharide (1995) (89)
Incomplete inhibition of the pressor effects of endothelin‐1 and related peptides in the anaesthetized rat with BQ‐123 provides evidence for more than one vasoconstrictor receptor (1993) (89)
High density lipoproteins reduce organ injury and organ dysfunction in a rat model of hemorrhagic shock (2001) (88)
Limitation of myocardial infarct size in the rabbit by ischaemic preconditioning is abolished by sodium 5-hydroxydecanoate. (1996) (87)
Insulin Reduces Cerebral Ischemia/Reperfusion Injury in the Hippocampus of Diabetic Rats (2009) (87)
A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock. (1999) (87)
Minimum Quality Threshold in Pre-Clinical Sepsis Studies (Mqtipss): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis (2018) (85)
Inhibitors of poly (ADP-ribose) synthetase protect rat cardiomyocytes against oxidant stress. (1999) (84)
Comparison of the effects of aminoguanidine and N omega-nitro-L-arginine methyl ester on the multiple organ dysfunction caused by endotoxaemia in the rat. (1996) (84)
Inhibitors of poly (ADP-ribose) synthetase protect rat proximal tubular cells against oxidant stress. (1999) (84)
Nifedipine inhibits the induction of nitric oxide synthase by bacterial lipopolysaccharide. (1993) (82)
Endothelin‐1 Releases Prostacyclin and Inhibits ex vivo Platelet Aggregation in the Anesthetized Rabbit (1989) (81)
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure. (2004) (81)
TLR9 mediates cellular protection by modulating energy metabolism in cardiomyocytes and neurons (2013) (80)
Ranolazine, a partial fatty acid oxidation inhibitor, reduces myocardial infarct size and cardiac troponin T release in the rat. (2001) (79)
High density lipoprotein (HDL) reduces renal ischemia/reperfusion injury. (2003) (79)
Intrarenal haemodynamics and renal dysfunction in endotoxaemia: effects of nitric oxide synthase inhibition (1997) (78)
Interleukin-1 contributes to the induction of nitric oxide synthase by endotoxin in vivo. (1993) (78)
Decline in the expression of copper/zinc superoxide dismutase in the kidney of rats with endotoxic shock: Effects of the superoxide anion radical scavenger, tempol, on organ injury (1998) (78)
Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis (2018) (77)
Erythropoietin attenuates acute kidney dysfunction in murine experimental sepsis by activation of the β-common receptor. (2013) (75)
Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton. (2004) (74)
ACTIVATION OF THE LIVER X RECEPTOR PROTECTS AGAINST HEPATIC INJURY IN ENDOTOXEMIA BY SUPPRESSING KUPFFER CELL ACTIVATION (2006) (74)
Inhibitors of Poly(ADP-Ribose) Polymerase Modulate Signal Transduction Pathways and Secondary Damage in Experimental Spinal Cord Trauma (2005) (73)
Inhibition by spermine of the induction of nitric oxide synthase in J774.2 macrophages: requirement of a serum factor (1994) (73)
Inhibition of IκB kinase reduces the multiple organ dysfunction caused by sepsis in the mouse (2013) (73)
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute pancreatitis induced by cerulein (2004) (72)
Peptidoglycan primes for LPS-induced release of proinflammatory cytokines in whole human blood. (2001) (72)
12‐Lipoxygenase‐derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1 (2007) (72)
INHIBITORS OF NADPH OXIDASE REDUCE THE ORGAN INJURY IN HEMORRHAGIC SHOCK (2005) (72)
Calpain inhibitor I reduces the development of acute and chronic inflammation. (2000) (71)
Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643. (2006) (71)
TREATMENT WITH THE GLYCOGEN SYNTHASE KINASE-3&bgr; INHIBITOR, TDZD-8, AFFECTS TRANSIENT CEREBRAL ISCHEMIA/REPERFUSION INJURY IN THE RAT HIPPOCAMPUS (2008) (71)
Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study. (2009) (71)
ALTERATIONS IN INFLAMMATORY CAPACITY AND TLR EXPRESSION ON MONOCYTES AND NEUTROPHILS AFTER CARDIOPULMONARY BYPASS (2007) (71)
Induction of NO synthesis by lipoteichoic acid from Staphylococcus aureus in J774 macrophages: involvement of a CD14-dependent pathway. (1997) (71)
Role of inducible nitric oxide synthase in the reduced responsiveness of the myocardium to catecholamines in a hyperdynamic, murine model of septic shock* (2006) (70)
Flipping the molecular switch for innate protection and repair of tissues: Long-lasting effects of a non-erythropoietic small peptide engineered from erythropoietin. (2015) (70)
Inhibitors of the activity of poly (ADP‐ribose) synthetase reduce the cell death caused by hydrogen peroxide in human cardiac myoblasts (1998) (69)
Glibenclamide‐induced inhibition of the expression of inducible nitric oxide synthase in cultured macrophages and in the anaesthetized rat (1995) (68)
Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of collagen-induced arthritis. (2000) (68)
Beneficial effects of tempol, a membrane-permeable radical scavenger, on the multiple organ failure induced by zymosan in the rat (2001) (68)
Protective role of peroxisome proliferator-activated receptor-β/δ in septic shock. (2010) (68)
GLYCOGEN SYNTHASE KINASE-3&bgr; INHIBITORS PROTECT AGAINST THE ORGAN INJURY AND DYSFUNCTION CAUSED BY HEMORRHAGE AND RESUSCITATION (2006) (67)
Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury (2006) (67)
Peptidoglycan of Staphylococcus aureus causes inflammation and organ injury in the rat* (2004) (67)
Diadenosine Tetraphosphate Protects against Injuries Induced by Ischemia and 6-Hydroxydopamine in Rat Brain (2003) (66)
Biosynthesis and interaction of endothelium-derived vasoactive mediators. (1991) (66)
Evidence from receptor antagonists of an important role for ETB receptor‐mediated vasoconstrictor effects of endothelin‐1 in the rat kidney (1994) (64)
Glycogen synthase kinase-3β inhibition attenuates the development of ischaemia/reperfusion injury of the gut (2007) (64)
Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice. (2010) (64)
Effects of tempol, a membrane-permeable radical scavenger, in a rodent model of carrageenan-induced pleurisy. (2000) (64)
Insulin reduces the multiple organ injury and dysfunction caused by coadministration of lipopolysaccharide and peptidoglycan independently of blood glucose: Role of glycogen synthase kinase-3&bgr; inhibition* (2006) (63)
Effect of interleukin‐4 and interleukin‐10 on leucocyte migration and nitric oxide production in the mouse (1995) (63)
An inhibitor of poly (ADP‐ribose) synthetase activity reduces contractile dysfunction and preserves high energy phosphate levels during reperfusion of the ischaemic rat heart (1999) (63)
Modification of energy metabolism and radiation response of a murine tumour by changes in nitric oxide availability. (1993) (63)
Beneficial effects of GW274150, a novel, potent and selective inhibitor of iNOS activity, in a rodent model of collagen-induced arthritis. (2002) (62)
Erythropoietin Reduces the Development of Experimental Inflammatory Bowel Disease (2004) (62)
PEPTIDOGLYCAN-AN ENDOTOXIN IN ITS OWN RIGHT? (2006) (62)
Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat (1996) (62)
Ischemic Conditioning Protects the Uremic Heart in a Rodent Model of Myocardial Infarction (2012) (61)
Junctional Adhesion Molecule–C Mediates Leukocyte Infiltration in Response to Ischemia Reperfusion Injury (2009) (61)
Lipoteichoic acid induces delayed protection in the rat heart: A comparison with endotoxin. (2000) (61)
THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ LIGAND 15-DEOXYD12,14 PROSTAGLANDIN J2 REDUCES THE ORGAN INJURY IN HEMORRHAGIC SHOCK (2004) (60)
Simvastatin reduces infarct size in a model of acute myocardial ischemia and reperfusion in the rat. (2003) (60)
Role of peroxisome proliferator-activated receptor-&ggr; in the protection afforded by 15-deoxy&Dgr;12,14 prostaglandin J2 against the multiple organ failure caused by endotoxin (2004) (60)
Effects of inhibitors of the activity of cyclo‐oxygenase‐2 on the hypotension and multiple organ dysfunction caused by endotoxin: A comparison with dexamethasone (1998) (60)
The effects of the endothelin ETA receptor antagonist, FR 139317, on infarct size in a rabbit model of acute myocardial ischaemia and reperfusion (1994) (60)
Delayed circulatory failure due to the induction of nitric oxide synthase by lipoteichoic acid from Staphylococcus aureus in anaesthetized rats (1995) (60)
Erythropoietin attenuates cardiac dysfunction in experimental sepsis in mice via activation of the β-common receptor (2013) (60)
Ligands of the peroxisome proliferator-activated receptor-PPAR-a reduce myocardial infarct size. (2002) (60)
Peptidoglycan of Staphylococcus aureus Upregulates Monocyte Expression of CD14, Toll-Like Receptor 2 (TLR2), and TLR4 in Human Blood: Possible Implications for Priming of Lipopolysaccharide Signaling (2005) (60)
Endothelin inhibits ex vivo platelet aggregation in the rabbit. (1988) (60)
Superoxide dismutase mimetic with catalase activity, EUK-134, attenuates the multiple organ injury and dysfunction caused by endotoxin in the rat. (2002) (59)
The mechanism of the inhibitory effect of polyamines on the induction of nitric oxide synthase: role of aldehyde metabolites (1994) (59)
Activation of soluble guanylyl cyclase by a factor other than nitric oxide or carbon monoxide contributes to the vascular hyporeactivity to vasoconstrictor agents in the aorta of rats treated with endotoxin. (1994) (59)
Refinement of Animal Models of Sepsis and Septic Shock (2015) (59)
Anti-inflammatory properties of enamel matrix derivative in human blood. (2006) (59)
The contribution of tumour necrosis factor‐α and endothelin‐1 to the increase of coronary resistance in hearts from rats treated with endotoxin (1995) (58)
Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage (2018) (58)
Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo. (2007) (58)
Endothelium-derived relaxing factor participates in the increased blood flow in response to pentagastrin in the rat stomach mucosa (1990) (58)
Reduction of the multiple organ injury and dysfunction caused by endotoxemia in 5‐lipoxygenase knockout mice and by the 5‐lipoxygenase inhibitor zileuton (2004) (58)
Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury. (2005) (57)
Glycogen Synthase Kinase-3β Inhibition Reduces Secondary Damage in Experimental Spinal Cord Trauma (2006) (56)
The selective PPARgamma antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion. (2005) (56)
Superoxide Dismutase Mimetics with Catalase Activity Reduce the Organ Injury in Hemorrhagic Shock (2002) (56)
Reduction of myocardial infarct size with sCR1sLex, an alternatively glycosylated form of human soluble complement receptor type 1 (sCR1), possessing sialyl Lewis x (1999) (55)
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-&ggr;, reduces the development of nonseptic shock induced by zymosan in mice* (2004) (55)
5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion. (2004) (54)
Inducible Nitric Oxide Synthase-Deficient Mice Exhibit Resistance to the Acute Pancreatitis Induced by Cerulein (2002) (54)
Mechanisms of Disease: cell death in acute renal failure and emerging evidence for a protective role of erythropoietin (2005) (54)
Imidazoquinolinone, Imidazopyridine, and Isoquinolindione Derivatives as Novel and Potent Inhibitors of the Poly(ADP-ribose) Polymerase (PARP): A Comparison with Standard PARP Inhibitors (2008) (54)
Calpain inhibitor I reduces colon injury caused by dinitrobenzene sulphonic acid in the rat (2001) (53)
Identification of copper/zinc superoxide dismutase as a novel nitric oxide‐regulated gene in rat glomerular mesangial cells and kidneys of endotoxemic rats (1999) (53)
Nitric oxide synthase in the rat fallopian tube is regulated during the oestrous cycle. (1995) (53)
Absence of endogenous interleukin-6 enhances the inflammatory response during acute pancreatitis induced by cerulein in mice. (2002) (53)
Agonists of peroxisome-proliferator activated receptor-alpha (clofibrate and WY14643) reduce renal ischemia/reperfusion injury in the rat. (2002) (53)
The Cardioprotective Effects of Preconditioning with Endotoxin, but Not Ischemia, Are Abolished by a Peroxisome Proliferator-Activated Receptor-γ Antagonist (2005) (52)
Inhibition of oxygen-centered free radical formation by the stable prostacyclin-mimetic iloprost (ZK 36 374) in acute myocardial ischemia. (1984) (52)
Interactions between lipoteichoic acid and peptidoglycan from Staphylococcus aureus: a structural and functional analysis. (2002) (51)
Effect of selective blockade of endothelin ETB receptors on the liver dysfunction and injury caused by endotoxaemia in the rat (1996) (51)
Erythropoietin reduces the degree of arthritis caused by type II collagen in the mouse. (2005) (51)
Targeting the NLRP3 inflammasome to Reduce Diet-induced Metabolic Abnormalities in Mice (2015) (51)
Review: PPARs as new therapeutic targets for the treatment of cerebral ischemia/reperfusion injury (2008) (50)
The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat. (2002) (50)
Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury (2013) (49)
Effects of inhibitors of the activity of poly (ADP‐ribose) synthetase on the liver injury caused by ischaemia‐reperfusion: a comparison with radical scavengers (1998) (49)
Dihydropyridine antagonists and agonists of calcium channels inhibit the induction of nitric oxide synthase by endotoxin in cultured macrophages. (1993) (49)
Part I: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Study Design and Humane Modeling Endpoints. (2019) (49)
Inhibition of glycogen synthase kinase‐3β attenuates the development of carrageenan‐induced lung injury in mice (2006) (49)
Selective activation of the prostanoid EP(3) receptor reduces myocardial infarct size in rodents. (1999) (49)
The MEK Inhibitor Trametinib Ameliorates Kidney Fibrosis by Suppressing ERK1/2 and mTORC1 Signaling. (2018) (49)
Endothelin‐1 inhibits platelet aggregation in vivo: a study with 111indium‐labelled platelets (1990) (49)
Tempol, a membrane-permeable radical scavenger, reduces dinitrobenzene sulfonic acid-induced colitis. (2000) (48)
Corrigendum to “Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: Effects of the PPAR-α agonist WY14643” [Free Radic. Biol. Med. 41: 579–589; 2006] (2006) (48)
Annexin-A1: Therapeutic Potential in Microvascular Disease (2019) (48)
Reversal of the deleterious effects of chronic dietary HFCS-55 intake by PPAR-δ agonism correlates with impaired NLRP3 inflammasome activation. (2013) (48)
Lysophosphatidylcholine reduces the organ injury and dysfunction in rodent models of Gram‐negative and Gram‐positive shock (2006) (47)
EFFECTS OF 5‐AMINOISOQUINOLINONE, A WATER‐ SOLUBLE, POTENT INHIBITOR OF THE ACTIVITY OF POLY (ADP‐RIBOSE) POLYMERASE, IN A RODENT MODEL OF LUNG INJURY.: 9 (2001) (47)
LIVER X RECEPTOR IS A KEY REGULATOR OF CYTOKINE RELEASE IN HUMAN MONOCYTES (2007) (47)
The role of cycloxygenase-2 in the rodent kidney following ischaemia/reperfusion injury in vivo. (2007) (47)
Induction of hypoxia in experimental murine tumors by the nitric oxide synthase inhibitor, NG-nitro-L-arginine. (1994) (46)
Peroxisome proliferator-activated receptor β/δ agonism protects the kidney against ischemia/reperfusion injury in diabetic rats. (2011) (46)
Pharmacological preconditioning with erythropoietin attenuates the organ injury and dysfunction induced in a rat model of hemorrhagic shock (2012) (46)
Reduction of myocardial reperfusion injury by an inhibitor of poly (ADP-ribose) synthetase in the pig. (1998) (46)
Sirolimus Interferes with the Innate Response to Bacterial Products in Human Whole Blood by Attenuation of IL‐10 Production (2001) (46)
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut. (2003) (45)
Usefulness of defibrotide in protecting ischemic myocardium from early reperfusion damage. (1985) (45)
A novel, potent and selective inhibitor of the activity of inducible nitric oxide synthase (GW274150) reduces the organ injury in hemorrhagic shock. (2002) (45)
Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes (2017) (45)
Reduction by prostaglandin E1 or prostaglandin E0 of myocardial infarct size in the rabbit by activation of ATP‐sensitive potassium channels (1995) (45)
Inhibitors of calpain activation (PD150606 and E-64) and renal ischemia-reperfusion injury. (2005) (45)
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury. (2001) (44)
Nitric oxide synthase inhibitors. (2000) (43)
Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of splanchnic artery occlusion and reperfusion. (2000) (43)
The Hemodynamic Effects of Endothelin‐1 in the Pithed Rat (1989) (43)
Tempol reduces the activation of nuclear factor-kappaB in acute inflammation. (2004) (43)
Defibrotide reduces infarct size in a rabbit model of experimental myocardial ischaemia and reperfusion (1989) (42)
Treatment of acute myocardial ischaemia with a selective antagonist of thromboxane receptors (BM 13.177) (1986) (42)
Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform. (1995) (42)
LIVER X RECEPTOR AGONIST GW3965 DOSE-DEPENDENTLY REGULATES LPS-MEDIATED LIVER INJURY AND MODULATES POSTTRANSCRIPTIONAL TNF-&agr; PRODUCTION AND P38 MITOGEN-ACTIVATED PROTEIN KINASE ACTIVATION IN LIVER MACROPHAGES (2009) (42)
Tempol, an intracelullar free radical scavenger, reduces liver injury in hepatic ischemia-reperfusion in the rat. (2004) (41)
Endotoxin induces a second window of protection in the rat heart as determined by using p-nitro-blue tetrazolium staining, cardiac troponin T release, and histology. (1999) (41)
IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD. (2017) (41)
Inhibitors of Poly(ADP-Ribose) Polymerase Modulate Signal Transduction Pathways and the Development of Bleomycin-Induced Lung Injury (2005) (41)
Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock (1995) (40)
EFFECTS OF INHIBITORS OF POLY(ADP-RIBOSE) SYNTHETASE ACTIVITY ON HYPOTENSION AND MULTIPLE ORGAN DYSFUNCTION CAUSED BY ENDOTOXIN (1998) (40)
Glycogen synthase kinase-3 beta inhibition reduces secondary damage in experimental spinal cord trauma. (2006) (40)
Peroxisome Proliferator-Activated Receptor-α Contributes to the Resolution of Inflammation after Renal Ischemia/Reperfusion Injury (2009) (40)
Upregulation of ICAM-1 expression on J774.2 macrophages by endotoxin involves activation of NF-kappaB but not protein tyrosine kinase: comparison to induction of iNOS. (1999) (40)
Erythropoietin reduces the development of nonseptic shock induced by zymosan in mice* (2006) (40)
The induction of cyclo-oxygenase-2 in human pulmonary epithelial cell culture (A549) activated by IL-1beta is inhibited by tyrosine kinase inhibitors. (1996) (39)
Protection of the myocardium by ischaemic preconditioning: mechanisms and therapeutic implications. (1996) (39)
Single-dose intravenous simvastatin treatment attenuates renal injury in an experimental model of ischemia-reperfusion in the rat. (2006) (39)
Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis (2018) (39)
EUK-134 Reduces Renal Dysfunction and Injury Caused by Oxidative and Nitrosative Stress of the Kidney (2004) (38)
Evidence for the Role of Peroxisome Proliferator-Activated Receptor-β/δ in the Development of Spinal Cord Injury (2010) (38)
Delayed Administration of Pyroglutamate Helix B Surface Peptide (pHBSP), a Novel Nonerythropoietic Analog of Erythropoietin, Attenuates Acute Kidney Injury (2012) (38)
New targets of urocortin-mediated cardioprotection (2010) (38)
PEPTIDOGLYCAN OF STAPHYLOCCUS AUREUS INDUCES ENHANCED LEVELS OF MATRIX METALLOPROTEINASE-9 IN HUMAN BLOOD ORIGINATING FROM NEUTROPHILS (2005) (37)
Inhibition of Bruton's TK regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation (2020) (37)
INTERLEUKIN‐13 IS A MORE POTENT INHIBITOR OF THE EXPRESSION OF INDUCIBLE NITRIC OXIDE SYNTHASE IN SMOOTH MUSCLE CELLS THAN IN MACROPHAGES: A COMPARISON WITH INTERLEUKIN‐4 AND INTERLEUKIN‐10 (1995) (37)
A Nonerythropoietic Peptide that Mimics the 3D Structure of Erythropoietin Reduces Organ Injury/Dysfunction and Inflammation in Experimental Hemorrhagic Shock (2011) (36)
Gender Dimorphism of the Cardiac Dysfunction in Murine Sepsis: Signalling Mechanisms and Age-Dependency (2014) (36)
Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes (2019) (36)
Endothelins release tissue plasminogen activator and prostanoids. (1990) (36)
Differential effects of caspase inhibitors on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney. (2004) (36)
A superoxide dismutase mimetic with catalase activity (EUK-8) reduces the organ injury in endotoxic shock. (2003) (36)
Inducible nitric oxide synthase-deficient mice exhibit resistance to the acute pancreatitis induced by cerulein. (2001) (36)
Inhibition of the production of nitric oxide and vasodilator prostaglandins attenuates the cardiovascular response to bacterial endotoxin in adrenalectomized rats (1993) (36)
Inhibition of IκB Kinase Attenuates the Organ Injury and Dysfunction Associated with Hemorrhagic Shock (2015) (36)
Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice (2003) (35)
Membrane-permeable radical scavenger, tempol, reduces multiple organ injury in a rodent model of Gram-positive shock (2000) (35)
Effects of the prostanoid EP3‐receptor agonists M&B 28767 and GR 63799X on infarct size caused by regional myocardial ischaemia in the anaesthetized rat (1999) (35)
Peptidoglycan and Lipoteichoic Acid Modify Monocyte Phenotype in Human Whole Blood (2001) (35)
Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis (2016) (34)
ACTIVATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-&bgr;/&dgr; ATTENUATES MYOCARDIAL ISCHEMIA/REPERFUSION INJURY IN THE RAT (2010) (34)
Novel applications of recombinant erythropoietin. (2006) (33)
GW0742, a High Affinity PPAR-β/δ Agonist Reduces Lung Inflammation Induced by Bleomycin Instillation in Mice (2010) (33)
Carboxy-Ptio, a Scavenger of Nitric Oxide, Selectively Inhibits the Increase in Medullary Perfusion and Improves Renal Function in Endotoxemia (2002) (33)
15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria. (2004) (33)
Inhaled CO: Deadly gas or novel therapeutic? (2001) (32)
Effects of inhibitors of the activity of poly (ADP‐ribose) synthetase on the organ injury and dysfunction caused by haemorrhagic shock (1999) (32)
Acute protective effects of simvastatin in the rat model of renal ischemia-reperfusion injury: it is never too late for the pretreatment. (2008) (31)
Endogenous ligands of PPAR-γ reduce the liver injury in haemorrhagic shock (2004) (31)
GW0742, A HIGH-AFFINITY PPAR -&bgr;/&dgr; AGONIST, INHIBITS ACUTE LUNG INJURY IN MICE (2010) (30)
Peroxisome proliferator-activated receptor-γ antagonists GW9662 and T0070907 reduce the protective effects of lipopolysaccharide preconditioning against organ failure caused by endotoxemia* (2006) (30)
Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia (2014) (30)
Pyrrolidine dithiocarbamate reduces renal dysfunction and injury caused by ischemia/reperfusion of the rat kidney. (2003) (30)
GLYCOGEN SYNTHASE KINASE 3&bgr; INHIBITION REDUCES THE DEVELOPMENT OF NONSEPTIC SHOCK INDUCED BY ZYMOSAN IN MICE (2006) (30)
Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation. (2017) (29)
The synthetic antimicrobial peptide 19-2.5 attenuates septic cardiomyopathy and prevents down-regulation of SERCA2 in polymicrobial sepsis (2016) (29)
LYSOPHOSPHATIDIC ACID REDUCES THE ORGAN INJURY CAUSED BY ENDOTOXEMIA-A ROLE FOR G-PROTEIN-COUPLED RECEPTORS AND PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-&ggr; (2007) (29)
An in vivo model of ischemia/reperfusion and inflammation of the kidneys of the rat. (2003) (29)
FMRF-amide and L-Arg-L-Phe increase blood pressure and heart rate in the anaesthetised rat by central stimulation of the sympathetic nervous system. (1991) (29)
The hidden role of NLRP3 inflammasome in obesity‐related COVID‐19 exacerbations: Lessons for drug repurposing (2020) (29)
HIGH-DENSITY LIPOPROTEINS REDUCE THE INTESTINAL DAMAGE ASSOCIATED WITH ISCHEMIA/REPERFUSION AND COLITIS (2004) (28)
The effect of iNOS deletion on hepatic gluconeogenesis in hyperdynamic murine septic shock (2007) (28)
Mediation of endothelin‐1‐induced inhibition of platelet aggregation via the ETB receptor (1993) (28)
Regional Vascular Resistance and Haemodynamics in the Spontaneously Hypertensive Rat: The Effects of Bradykinin (1990) (27)
Endothelin-3: selectivity as an anti-aggregatory peptide in vivo. (1989) (27)
Lipoteichoic acid from Staphylococcus aureus reduces renal ischemia/reperfusion injury. (2002) (27)
Inhibition by N‐acetyl‐5‐hydroxytryptamine of nitric oxide synthase expression in cultured cells and in the anaesthetized rat (1995) (27)
Bone marrow mononuclear cells reduce myocardial reperfusion injury by activating the PI3K/Akt survival pathway. (2010) (27)
The selective guanylate cyclase inhibitor ODQ reduces multiple organ injury in rodent models of Gram-positive and Gram-negative shock (2001) (26)
The PPAR-γ ligand 15-deoxyΔ12,14 prostaglandin J2 reduces the liver injury in endotoxic shock (2003) (26)
Organ Injury and Cytokine Release Caused by Peptidoglycan Are Dependent on the Structural Integrity of the Glycan Chain (2004) (26)
5-Aminoisoquinolinone reduces colon injury by experimental colitis (2004) (26)
Erythropoietin in the intensive care unit: beyond treatment of anemia (2011) (26)
Combination immunotherapy which neutralises the effects of TNF alpha and IL-1 beta attenuates the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat. (1997) (26)
L-Arginine infusion after ischaemia-reperfusion of rat kidney enhances lipid peroxidation. (1996) (25)
Linagliptin Attenuates the Cardiac Dysfunction Associated With Experimental Sepsis in Mice With Pre-existing Type 2 Diabetes by Inhibiting NF-κB (2018) (25)
Endothelin‐1 ‐induced reduction of myocardial infarct size by activation of ATP‐sensitive potassium channels in a rabbit model of myocardial ischaemia and reperfusion (1995) (25)
A non‐erythropoietic peptide derivative of erythropoietin decreases susceptibility to diet‐induced insulin resistance in mice (2014) (25)
The tyrosine kinase inhibitor tyrphostin AG126 reduces the development of acute and chronic inflammation. (2000) (25)
Inhibition of the induction of nitric oxide synthase by spermine is modulated by aldehyde dehydrogenase. (1994) (25)
Vasoconstriction in the rat kidney induced by endothelin-1 is blocked by PD 145065. (1993) (24)
Senescence and the Aging Immune System as Major Drivers of Chronic Kidney Disease (2020) (24)
Models of coronary artery occlusion and reperfusion for the discovery of novel antiischemic and antiinflammatory drugs for the heart. (2003) (24)
Quantification of microcirculatory blood flow: a sensitive and clinically relevant prognostic marker in murine models of sepsis (2014) (24)
Modeling Acute Traumatic Hemorrhagic Shock Injury: Challenges and Guidelines for Preclinical Studies (2017) (24)
Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice (2019) (24)
Cytokine Responses to CpG DNA in Human Leukocytes (2006) (24)
Hydrogen sulfide and sulfite: novel mediators in the pathophysiology of shock and inflammation. (2005) (24)
The thromboxane receptor antagonist, daltroban, protects the myocardium from ischaemic injury resulting in suppression of leukocytosis. (1988) (23)
Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis. (2020) (23)
Identification of manganese superoxide dismutase as a NO-regulated gene in rat glomerular mesangial cells by 2D gel electrophoresis. (2003) (23)
Selective activation of E-type prostanoid(3)-receptors reduces myocardial infarct size. A novel insight into the cardioprotective effects of prostaglandins. (2000) (23)
Role for intracellular platelet‐activating factor in the circulatory failure in a model of Gram‐positive shock (1995) (23)
Reduction of myocardial injury by the EP3 receptor agonist TEI-3356. Role of protein kinase C and of K(ATP)-channels. (1999) (23)
The tyrosine kinase inhibitor tyrphostin AG 126 reduces the multiple organ failure induced by zymosan in the rat (2002) (23)
The tyrosine kinase inhibitor tyrphostin AG126 reduces renal ischemia/reperfusion injury in the rat. (2003) (23)
Development and validation of a reinforcement learning algorithm to dynamically optimize mechanical ventilation in critical care (2021) (22)
Inhibition of glycogen synthase kinase-3beta attenuates the development of carrageenan-induced lung injury in mice. (2006) (22)
Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis (2017) (22)
The stable nitroxide, tempol, attenuates the effects of peroxynitrite and oxygen-derived free radicals. (2001) (22)
Tyrphostin reduces the organ injury in haemorrhagic shock: role of inducible nitric oxide synthase. (2003) (22)
Downregulation of SPARC expression is mediated by nitric oxide in rat mesangial cells and during endotoxemia in the rat. (2000) (21)
[Heart in sepsis : Molecular mechanisms, diagnosis and therapy of septic cardiomyopathy]. (2017) (21)
Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation (2017) (21)
TEMPONE reduces renal dysfunction and injury mediated by oxidative stress of the rat kidney. (2002) (21)
Lipoteichoic acid is a potent inducer of cytokine production in rat and human Kupffer cells in vitro. (2003) (21)
The effects of endothelium‐dependent vasodilators on cardiac output and their distribution in the anaesthetized rat: a comparison with sodium nitroprusside (1988) (21)
Effects of calpain inhibitor I on multiple organ failure induced by zymosan in the rat* (2002) (20)
Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care (2012) (20)
Lipid A and the lipid A analogue anti-tumour compound ONO-4007 induce nitric oxide synthase in vitro and in vivo. (1995) (20)
Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow (2013) (20)
Liver X receptor protects against liver injury in sepsis caused by rodent cecal ligation and puncture. (2011) (20)
The Tyrosine Kinase Inhibitor Tyrphostin AG 126 Reduces the Development of Colitis in the Rat (2000) (20)
PEPTIDOGLYCAN OF S. AUREUS CAUSES INCREASED LEVELS OF MATRIX METALLOPROTEINASES IN THE RAT (2004) (20)
Sphingosylphosphorylcholine reduces the organ injury/dysfunction and inflammation caused by endotoxemia in the rat (2008) (20)
Sulprostone‐induced reduction of myocardial infarct size in the rabbit by activation of ATP‐sensitive potassium channels (1996) (19)
Neutrophil elastase plays a non‐redundant role in remodeling the venular basement membrane and neutrophil diapedesis post‐ischemia/reperfusion injury (2019) (19)
Inhibition of glycogen synthase kinase (GSK)-3-β improves liver microcirculation and hepatocellular function after hemorrhagic shock. (2014) (19)
Role of PPAR-δ in the development of zymosan-induced multiple organ failure: an experiment mice study (2010) (19)
Protection of the ischemic myocardium from reperfusion injury by prostaglandin E1 inhibition of ischemia-induced neutrophil activation (1988) (19)
Modification of metabolism of transplantable and spontaneous murine tumors by the nitric oxide synthase inhibitor, nitro-L-arginine. (1994) (18)
Biological control and inhibition of induction of nitric oxide synthase. (1996) (18)
Inhibiting Glycogen Synthase Kinase 3β in Sepsis (2007) (18)
Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock. (1995) (18)
Baricitinib counteracts metaflammation, thus protecting against diet-induced metabolic abnormalities in mice (2020) (18)
Beneficial effects of 5-aminoisoquinolinone, a novel, potent, water-soluble, inhibitor of poly (ADP-ribose) polymerase, in a rat model of splanchnic artery occlusion and reperfusion. (2004) (18)
Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock (2017) (18)
Nitric oxide, bacteria, and host defense in sepsis: who needs what? (2004) (18)
Erythropoietin Preserves the Integrity and Quality of Organs for Transplantation After Cardiac Death (2011) (17)
Activation of cytokine synthesis by systemic infusions of lipopolysaccharide and peptidoglycan in a porcine model in vivo and in vitro. (2007) (17)
Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states (2015) (17)
Effects of the PPAR-β/δ agonist GW0742 during resuscitated porcine septic shock (2013) (17)
Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water (2016) (16)
Beneficial effects of erythropoietin in preclinical models of shock and organ failure (2007) (16)
The endothelin ETB receptor agonist, IRL 1620, causes vasodilatation and inhibits ex vivo platelet aggregation in the anaesthetised rabbit. (1994) (16)
Selective activation of E-type prostanoid3-receptors reduces myocardial infarct size (2000) (16)
The Use of Selective Inhibitors of Inducible Nitric Oxide Synthase in Septic Shock (1998) (15)
A novel model of reno-cardiac syndrome in the C57BL/ 6 mouse strain (2018) (15)
Corticosteroids and cardioprotection (2002) (15)
Glycogen Synthase Kinase-3β Inhibition Attenuates the Development of Bleomycin-Induced Lung Injury (2007) (15)
Endogenous ligands of PPAR-gamma reduce the liver injury in haemorrhagic shock. (2004) (14)
Inhibition of the activation of nuclear factor kappa B to reduce myocardial reperfusion injury and infarct size. (2004) (14)
Neuronal Nitric Oxide Synthase is Involved in Vascular Hyporeactivity and Multiple Organ Dysfunction Associated with Hemorrhagic Shock (2016) (14)
Inhibiting glycogen synthase kinase 3beta in sepsis. (2007) (14)
RECOMBINANT HUMAN ERYTHROPOIETIN PREVENTS LIPOPOLYSACCHARIDE-INDUCED VASCULAR HYPOREACTIVITY IN THE RAT (2009) (14)
Sepsis-3 on the Block: What Does It Mean for Preclinical Sepsis Modeling? (2017) (14)
Beneficial effects of GW274150 treatment on the development of experimental colitis induced by dinitrobenzene sulfonic acid. (2005) (14)
Ligands of the peroxisome proliferator‐activated receptor‐γ and heart failure (2004) (14)
Delayed Preconditioning Induced by Lipoteichoic Acid From B. Subtilis and S. Aureus Is Not Blocked by Administration of 5-Hydroxydecanoate (2002) (14)
The PPAR-gamma ligand 15-deoxy(delta12,14) prostaglandin J2 reduces the liver injury in endotoxic shock. (2003) (14)
Emerging drugs for renal failure (2003) (13)
Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale (2019) (13)
Development of novel, water-soluble inhibitors of poly (adenosine 5'-diphosphate ribose) synthetase activity for use in shock and ischemia-reperfusion injury. (2002) (13)
Role of Cytochrome P4502E1 Activation in Proximal Tubular Cell Injury Induced by Hydrogen Peroxide (2004) (13)
Modeling Cardiac Dysfunction Following Traumatic Hemorrhage Injury: Impact on Myocardial Integrity (2019) (13)
X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure (2020) (13)
The spice of life: curcumin reduces the mortality associated with experimental sepsis. (2006) (13)
MURAMYL DIPEPTIDE ENHANCES THE RESPONSE TO ENDOTOXIN TO CAUSE MULTIPLE ORGAN INJURY IN THE ANESTHETIZED RAT (2007) (13)
Endogenously generated arachidonate‐derived ligands for TRPV1 induce cardiac protection in sepsis (2018) (12)
‘Preconditioning’ with Low Dose Lipopolysaccharide Aggravates the Organ Injury / Dysfunction Caused by Hemorrhagic Shock in Rats (2015) (12)
Is endothelin-1 the regulator of myofibroblast contraction during wound healing? (1992) (12)
Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock (2019) (12)
Erythropoietin in the critically ill: do we ask the right questions? (2012) (12)
NG‐hydroxy‐L‐arginine prevents the haemodynamic effects of nitric oxide synthesis inhibition in the anaesthetized rat (1992) (12)
GLYCOGEN SYNTHASE KINASE-3?? INHIBITION REDUCES SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA (2006) (10)
Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood‐brain barrier: Therapeutic avenues (2021) (10)
A novel insight into the mechanism of the antithrombotic action of defibrotide. (1992) (10)
Changes in energy metabolism and X-ray sensitivity in murine tumours by the nitric oxide donor SIN-1. (1996) (10)
The β-d-Endoglucuronidase Heparanase Is a Danger Molecule That Drives Systemic Inflammation and Correlates with Clinical Course after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair: Lessons Learnt from Mice and Men (2017) (10)
The Antimalarial Drug Artesunate Attenuates Cardiac Injury in A Rodent Model of Myocardial Infarction. (2018) (10)
Eicosanoids and atherosclerosis (1993) (10)
Induction of Nitric Oxide and Tetrahydrobiopterin Synthesis by Lipoteichoic Acid from Staphylococcus aureus in VascularSmooth Muscle Cells (1998) (10)
GW274150 inhibits nitric oxide production by primary cultures of rat proximal tubular cells. (2003) (9)
RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance (2020) (9)
Heterogeneous receptors mediate endothelin-1-induced changes in blood pressure, hematocrit, and platelet aggregation. (1993) (9)
The Cyclopentenone Prostaglandin 15-Deoxy- -Prostaglandin J2 Attenuates the Development of Acute and Chronic Inflammation (2002) (9)
Morphological Analysis of the Iloprost Effects on Reperfused Ischemic Myocardium (1985) (9)
Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning (2018) (8)
Inhibition of the release of endothelium‐derived relaxing factor in vitro and in vivo by dipeptides containing NG‐nitro‐l‐arginine (1991) (8)
Hydrogen sulfide, neurogenic inflammation, and cardioprotection: a tale of rotten eggs and vanilloid receptors. (2010) (8)
Identification of AnnexinA 1 as an Endogenous Regulator of RhoA , and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes (2019) (8)
Inhibition of the activity of poly (ADP-ribose) polymerase in ischemia-reperfusion injury. (2000) (7)
Inhibition of Nitric Oxide Synthase Activity in Circulatory Shock: Friend or Foe? (1996) (7)
NO in Septic Shock (1997) (7)
SEPSIS-3 On the Block: What Does It Mean for Pre-Clinical Sepsis Modeling? (2017) (7)
Lipidomics Provides New Insight into Pathogenesis and Therapeutic Targets of the Ischemia—Reperfusion Injury (2021) (7)
Endothelin-1 and big endothelin cause subarachnoid hemorrhage in the anesthetized rabbit. (1991) (6)
Protection from myocardial ischemic injury in cats and pigs by defibrotide--different mode of action? (1989) (6)
The Anti-Malarial Drug Artesunate Attenuates Cardiac Injury in a Rodent Model of Myocardial Infarction. (2017) (6)
The induction of cyclooxygenase-2 elicited by endotoxin in endothelial cells and macrophages is inhibited by prostaglandin E1 and 13,14-dihydro prostaglandin E1. (1995) (6)
Catecholamines and the septic heart: opening Pandora's box? (2013) (6)
Comparison of the thromboxane synthetase inhibitor dazoxiben and the prostacyclin mimetic iloprost in an animal model of acute ischaemia and reperfusion. (1984) (6)
Inhibition of Induction or Activity of Nitric Oxide Synthase: Novel Approaches for the Therapy of Circulatory Shock (1995) (6)
Effects of 5-AIQ in a rat model of streptozotocin-induced diabetes (2003) (6)
Drugs which modulate nitric oxide homeostasis are likely to provide therapeutic benefit in cardiovascular disease. (1993) (5)
Relative Adrenal Insufficiency in Cardiogenic Shock: Is There a Need for Action? (2017) (5)
Targeting CCR2: a novel therapeutic strategy for septic shock? (2011) (5)
RG100204, A Novel Aquaporin-9 Inhibitor, Reduces Septic Cardiomyopathy and Multiple Organ Failure in Murine Sepsis (2022) (5)
Mitochondrial DNA in Acute Kidney Injury: Chicken or Egg? (2017) (5)
Reduction of infarct size in a rat model of regional myocardial ischemia and reperfusion by the synthetic peptide DAHK (2006) (5)
byactivation oftyrosine kinase inbovine endothelial cells stimulated by bacterial lipopolysacchari de (1995) (5)
NF-kB inhibition by pyrrolidine dithiocarbamate attenuates experimental acute pancreatitis (2003) (5)
Inhibitors of poly (ADP-ribose) synthetase protect rat renal proximal tubular cells against oxidant stress. (1998) (4)
Ligands of the peroxisome proliferator-activated receptor-gamma and heart failure. (2004) (4)
Niacin as a novel therapy for septic shock? (2011) (4)
Pleiotropic effects of atorvastatin in experimental sepsis: preservation of β1-adrenoreceptor signaling in the heart. (2014) (4)
Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis (2018) (4)
Eicosanoids in myocardial ischemia. (1989) (4)
Protein tyrosine kinase inhibitors as novel therapeutics for systemic inflammation, shock, and organ injury. (2003) (4)
TREATMENT WITH AMINOETHYLISOTHIOUREA A SELECTIVE INHIBITOR OF THE INDUCIBLE ISOFORM OF NITRIC OXIDE SYNTHASE IMPROVES LIVER CIRCULATION AND OXYGEN METABOLISM IN ENDOTOXEMIA.: 4 (1996) (4)
Reduction of the natural Activated protein C pathway activity significantly prevents coagulopathy in a murine model of acute traumatic coagulopathy (2014) (4)
Does Insulin Protect the Brain in Mice and Man with Sepsis? (2015) (4)
The inhibition of Macrophage Migration Inhibitory Factor by ISO-1 attenuates trauma-induced multiorgan dysfunction in rats (2021) (4)
Pharmacological Inhibition of FAK-Pyk2 Pathway Protects Against Organ Damage and Prolongs the Survival of Septic Mice (2022) (3)
Procalcitonin does not influence the surface expression of inflammatory receptors on whole blood leukocytes (2001) (3)
NG-monomethyl-L-arginine but not Nω-nitro-L-arginine is metabolized by endottielial cells to L-citrulline (1990) (3)
Selective inhibition of the activity of inducible nitric oxide synthase in septic shock. (1995) (3)
A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice (2021) (3)
A nonerythropoietic peptide derivative of erythropoietin decreases susceptibility to diet-induced insulin resistance in mice (3)
Urocortin does not reduce the renal injury and dysfunction caused by experimental ischaemia/reperfusion. (2004) (3)
Themultiple organ dysfunction syndrome caused byendotoxin in therat: attenuation ofliver dysfunction byinhibitors ofnitric oxide synthase (1995) (3)
Inhibitors of Nitric Oxide Biosynthesis (1999) (3)
Role of Nitric Oxide in the Pathogenesis of Gram-positive Shock (1996) (3)
233 NON-ARGININE BASED, SELECTIVE INHIBITORS OF INDUCIBLE NO SYNTHASE EXERT BENEFICIAL EFFECTS IN ENDOTOXIC SHOCK (1995) (3)
Delayed activation of PPAR-β/δ improves long-term survival in mouse sepsis: effects on organ inflammation and coagulation (2018) (3)
Endothelin‐1 Mediates the Increase in Ex Vivo Coronary Vascular Resistance Induced by Hemorrhagic Shock in the Anesthetized Rat (1995) (3)
Poly (ADP-Ribose) Polymerase Inhibitors and Acute Renal Failure (2002) (3)
Nω-nitro-L-arginine (NO2Arg) and NO2Arg-L-phenylalanine inhibit endothelium-dependent vasodilatations in vitro in rabbits and in vivo in the anaesthetized rat (1990) (2)
Inhibition of Bruton’s Tyrosine Kinase Activity Attenuates Hemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats (2021) (2)
The hidden role of NLRP3 inflammasome in diabesity-related COVID-19 exacerbations: lessons for drug repurposing (2020) (2)
Role of the beta-d-endoglucuronidase heparanase in septic cardiomyopathy (2017) (2)
Chapter 47 – Nitric Oxide and Septic Shock (2000) (2)
Humane end points in experimental models of septic shock: a must, not a superfluous nightmare for researchers! (2013) (2)
Selenium and Niacin for Sepsis Therapy: The Sum Is Greater Than Its Parts. (2016) (2)
Nitric oxide and endothelin-1 in circulatory shock involving cytokines (1999) (2)
Strategies to improve the quality of organs from DCD (2008) (2)
Advancements in nanomedicines for the detection and treatment of diabetic kidney disease (2022) (2)
Pre-treatment with high density lipoprotein (HDL) attenuates the renal and hepatic dysfunction caused by endotoxin in rats (2000) (2)
, in Culture Nitric Oxide Pathway in Vascular Smooth Muscle Cells − Relaxin Activates the l-Arginine (1998) (2)
Inhibition of Bruton’s tyrosine kinase reduces NF-kB and NLRP3 inflammasome activity preventing insulin resistance and microvascular disease (2019) (2)
The Effect of β2-Adrenoceptor Agonists on Leucocyte-Endothelial Adhesion in a Rodent Model of Laparotomy and Endotoxemia (2020) (2)
Nitric Oxide in Sepsis (2002) (2)
Stimulation of Vascular Prostacyclin Formation by Defibrotide: A New Strategy for Treatment of Acute Myocardial Ischaemia (1989) (2)
ICOS-Fc as innovative immunomodulatory approach to counteract inflammation and organ injury in sepsis (2022) (1)
The obesity paradox revisited: does increased body mass protect against circulatory shock? (2014) (1)
Endogenous hydrogen sulfide contributes to the cardioprotective effects of pre-conditioning with endotoxin, but not ischaemia, in the rat (2006) (1)
Inhibition of Bruton’s tyrosine kinase activity attenuates trauma-induced multiple organ dysfunction in rats (2021) (1)
Inhibition of Macrophage Migration Inhibitory Factor Activity Attenuates Haemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats (2022) (1)
THE TYROSIN KINASE INHIBITOR TYRPHOSTIN AG126 REDUCES THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RAT.: 186 (2002) (1)
ERYTHROPOETIN REDUCES THE RENAL INJURY CAUSED BY HEMORRHAGIC SHOCK OR ISCHEMIA REPERFUSION IN THE RAT.: 212 (2003) (1)
Editorial: Translational Insights Into Mechanisms and Therapy of Organ Dysfunction in Sepsis and Trauma (2020) (1)
Inhibition of NF-κB Pathway with IKK-16 or Linagliptin Attenuates the Cardiac Dysfunction Associated with Polymicrobial Sepsis in Mice with Preexisting Type 2 Diabetes Mellitus (T2DM) (2018) (1)
Nitric Oxide and Circulatory Shock (1999) (1)
Norepinephrine, the Intensivist's Swiss Army Knife for Circulatory Shock? (2016) (1)
Effects of defibrotide on infarct size and regional myocardial blood flow on the ischaemic reperfused rabbit heart. (1989) (1)
Evidence for the role of PPAR-{beta}/{delta} in the development of spinal cord injury (2010) (1)
Ischaemia and Reperfusion Enhances the Vasoconstrictor Effects of Endothelin-1 in the Isolated Perfused Heart of the Rat (1993) (1)
Inhibition of the activity of poly(ADP-ribose) polymerase in haemorrhagic shock (2003) (1)
Immunohistochemistry of Kidney a-SMA, Collagen 1, and Collagen 3, in A Novel Mouse Model of Reno-cardiac Syndrome. (2020) (1)
Successful treatment of acute myocardial ischaemia with teopranitol--a novel organic nitrate. (1986) (1)
COMPARISON OF THE INDOCTION PF CYCLO-OXYGENASE AND NITRIC OXIDE SYNTHASE BY ENDOTOXIN IN ENDOTOXIN IN ENDOTHELIAL CELLS AND MACROPHAGE (1995) (1)
Receptor-selective vasopressin analogs: a new push for "decatecholaminization"? (2013) (1)
Importance of Cell Wall Components of Gram-Positive Bacteria in Gram-Positive Septic Shock (1997) (1)
Inhibition of the JAK/STAT pathway with baricitinib reduces the multiple organ dysfunction caused by hemorrhagic shock in rats (2022) (1)
Vascular KATP channels protect from cardiac dysfunction and preserve cardiac metabolism during endotoxemia (2020) (1)
Effects of nitric oxide synthase inhibition (2006) (1)
Preservation of renal mitochondrial function in endotoxemic acute renal failure. (1997) (1)
Shock States and Nitric Oxide (2000) (1)
Effects of Glycogen Synthase Kinase‐beta Inhibition in Ischemia‐Reperfusion Injury of the Liver (2009) (1)
Effect of PJ-34 in a rat model of liver ischemia-reperfusion (2003) (1)
Mirror, mirror on the wall, is off-pump better than on-pump at all? (2014) (1)
Protection of the ischaemic myocardium from reperfusion injury by defibrotide and its possible mechanism of action. (1988) (1)
Pharmacology of the prostaglandin EP3 receptor agonist TEI-3356 (2006) (1)
Poly(ADP-Ribose) Polymerase and Ischemia-Reperfusion Injury (2006) (1)
Comparison of the Haemodynamic and Platelet-Inhibitory Effects of Endothelin-1 and Endothelin-3 in the Anaesthetized Rabbit1 (1990) (1)
PEPTIDOGLYCAN AND LPS INDUCE DISTINCT INTRACELLULAR SIGNALLING EVENTS IN WHOLE HUMAN BLOOD: 166 (2004) (1)
murine models of sepsis sensitive and clinically relevant prognostic marker in Quantification of microcirculatory blood flow: a (2015) (1)
Inhibition of the Activation of Nuclear Factor-κB as a Novel Therapeutic Approach for SIRS and Septic Shock (1998) (1)
EFFECTS OF HUMAN HIGH‐DENSITY LIPOPROTEINS (HDLS) ON THE MULTIPLE ORGAN INJURY IN HAEMORRHAGIC SHOCK: 497 (2004) (1)
Inhibition of endogenous hydrogen sulphide formation protects the liver from hepatic ischemia-reperfusion injury in the rat. (2006) (0)
Gram‐positive bacterial cell wall products upregulate surface expression of intercellular adhesion molecule 1, human leucocyte antigen DR and CD14 on monocytes in human whole blood (2000) (0)
Uninephrectomy and class II PI3K‐C2β inactivation synergistically protect against obesity, insulin resistance and liver steatosis in mice (2020) (0)
HUMAN RECONSTITUTED HIGH‐DENSITY LIPOPROTEIN ATTENUATES THE MULTIPLE ORGAN INJURY AND DYSFUNCTION IN HEMORRHAGIC SHOCK.: 210 (2001) (0)
reduction ofmyocardial infarct size by activation ofATP-sensitive potassium channels inarabbit model ofmyocardial ischaemia andreperfusion (1995) (0)
Activation protects against renal ischemia/reperfusion injury in diabetic rats (2009) (0)
Themechanism oftheinhibitory effect ofpolyamines on the induction ofnitric oxide synthase: role ofaldehyde metabolites (1994) (0)
Shock States and Nitric Oxide 19 (0)
Caused by Carrageenan Role of IL-6 in the Pleurisy and Lung Injury (1999) (0)
BENEFICIAL EFFECTS OF PPAR‐g AGONISTS IN SHOCK AND ISCHEMIA‐REPERFUSION INJURY: 505 (2004) (0)
What's new in Shock, September 2008? (2008) (0)
Pyrrolidine Dithiocarbamate Reduces Renal Dysfunction Associated with Ischaemia and Reperfusion of the Rat Kidney in Vivo (2002) (0)
113 NITRIC OXIDE AND MULTIPLE ORGAN FAILURE (1995) (0)
INHIBITION OF HYDROGEN SULFIDE SYNTHESIS PROTECTS THE RAT KIDNEY IN VIVO AGAINST ISCHEMIA-REPERFUSION INJURY (2006) (0)
High density lipoprotein for combating organ dysfunction due to hemorrhagic shocks (2000) (0)
Calpain inhibitor 1 reduces the renal dysfunction and injury assocated with ischaemia-reperfusion of the kidney of the rat in vivo (2000) (0)
Selectivity ofnonsteroidal antiinflammatory drugsasinhibitors of constitutive andinducible cyclooxygenase (1994) (0)
Corrigendum: Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-in-Silico Approach Combining In Vitro Experiments and Machine Learning (2020) (0)
MECHANISMS OF KUPFFER CELL ACTIVATION IN GRAM-POSITIVE SEPSIS.: 80 (2002) (0)
LYSOPHOSPHATIDIC ACID REDUCES THE ORGAN INJURY CAUSED BY ENDOTOXEMIA VIA ACTIVATION OF G-PROTEIN-COUPLED RECEPTORS, BUT NOT PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR&ggr; (2006) (0)
INHIBITION OF THE ACTIVITY OF POLY (ADP‐RIBOSE) POLYMERASE IN HEMORRHAGIC SHOCK: 361 (2004) (0)
PEPTIDOGLYCAN INDUCES THE RELEASE OF MATRIX METALLOPROTEINASE-9 (MMP-9) IN HUMAN BLOOD BY DEGRANULATION OF NEUTROPHILS: 495 (2004) (0)
MONOCYTE CELL SURFACE RECEPTOR UPREGULATION IN RESPONSE TO STIMULATION WITH LIPOPOLYSACCHARIDE AND PEPTIDOGLYCAN: 84 (2004) (0)
Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice: 231 (2003) (0)
What's New In shock , October 2006? (2006) (0)
ROLE OF BACTERIA AND ENDOTOXIN IN NITRIC OXIDE SYNTHASE INDUCTION AND RAT INTESTINAL INJURY PROVOKED BY NON-STEROID ANTI-INFLAMMATORY AGENTS (2007) (0)
INDUCIBLE NITRIC OXIDE SYNTHASE KNOCK OUT MICE EXHIBIT RESISTANCE TO THE ACUTE PANCREATITIS INDUCED BY CERULEIN.: 224 (2001) (0)
Uremia causes dysbiosis-mediated periodontal disease (2021) (0)
ROSIGLITAZONE. A PPAR‐I LIGAND, REDUCES THE DEVELOPMENT OF NON SEPTIC SHOCK: 512 (2004) (0)
EFFECTS OF IBUPROFEN ON INDUCIBLE NITRIC OXIDE SYNTHASE, HAEMODYNAMICS AND ORGAN DYSFUNCTION IN A RAT MODEL OF SEPTIC SHOCK: 663 (1997) (0)
What's New In shock , September 2006? (2006) (0)
Inhibition of EDRF Synthesis Reduces the Pentagastrin-Induced Hyperaemia of the Rat Gastric Mucosa (1991) (0)
Cardio-renal interface in translational and clinical research (2006) (0)
442P PLATELET-DERIVED NITRIC OXIDE IN HYPERTENSIVE AND NORMOTENSIVE CONTROL SUBJECTS (2007) (0)
Lipoteichoic Acid (LTA) Induces Delayed Protection in the Rat Heart: A Comparison with Endotoxin (LPS) (2000) (0)
PPAR-β/delta activatin protects against renal ischemia/reperfusion injury in diabetic rats (2009) (0)
Reduced expression of PPAR-β/δ limits the potential beneficial effects of GW0742 during septic shock in atherosclerotic swine (2012) (0)
EUK-134 reduces oxidative stress-mediated renal dysfunction and injury in the rat in vivo and in vitro (2001) (0)
PPAR‐gamma LIGANDS REDUCED THE DEVELOPMENT OF INTESTINAL ISCHEMIA/REPERFUSION: 204 (2003) (0)
GW274150 REDUCES ORGAN DYSFUNCTION CAUSED BY ISCHAEMIA/REPERFUSION AND HAEMORRHAGIC SHOCK.: 8 (2002) (0)
What's new in shock, March 2008. (2008) (0)
Abstract 12536: A Novel Toll-Like Receptor 9 Signaling in Cardiomyocytes (2011) (0)
Abstract 10806: The Role of Neuronal Nitric Oxide Synthase on the Vascular Hyporeactivity and Multiple Organ Failure Associated With Hemorrhagic Shock (2015) (0)
Caught between a rock and a hard place: seeking an optimal resuscitation strategy for hemorrhaging patients with lung injury. (2014) (0)
C 014 Differential Regulation Of Chemokine Expression And Recruitment Of Leukocytes In Females Underlies Sex-differences In Ischaemia / Reperfusion Injury (2010) (0)
BENEFICIAL EFFECTS OF ERYTHROPOEIN IN SHOCK AND ISCHEMIA REPERFUSION INJURY: 496 (2004) (0)
High density lipoprotein used to combat organ dysfunction after hemorrhagic shock. (2000) (0)
Enhanced sphingosine-1-phosphate levels by pharmacological or genetic approaches attenuate cardiac dysfunction in experimental septic cardiomyopathy (2015) (0)
Role of nitric oxide in hemorrhagic shock (1996) (0)
PRETREATMENT OF RATS WITH HEMOGLOBIN REDUCES THE MULTIPLE ORGAN INJURY CAUSED BY ENDOTOXIN.: 211 (2001) (0)
Effect of recombinant human erythropoietin in a rat model of ischemia-reperfusion injury of the liver (2004) (0)
ROLE OF INDUCIBLE NITRIC OXIDE SYNTHASE IN THE INITIATION OF THE INFLAMMATORY RESPONSE AFTER POSTISCHEMIC INJURY.: 89 (2001) (0)
Therapeutic Effects of Pyroglutamate Helix B Surface Peptide (pHBSP) in Disease (2013) (0)
Activation of TRPV1 by 12(s)‐HpETE and 20‐HETE Releases CGRP and Protects the Heart Against the Cardiac Dysfunction Caused by LPS (2016) (0)
Inhibition of no synthase activity reduces the skeletal muscle necrosis caused by ischaemia-reperfusion of the hindlimb (1997) (0)
Retraction notice to “Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury” [Int. J. Cardiol. 163 (2013) 326–334] (2019) (0)
The late inhibition of inhibitor of IkB kinase attenuates acute kidney injury and the subsequent development of fibrosis in a rato del of ischemia/reperfusion injury. (2015) (0)
The oDGal Mouse: A Novel, Physiologically Relevant Rodent Model of Sporadic Alzheimer’s Disease (2023) (0)
Calpain Inhibitor-I Reduces the Renal Dysfunction Associated with Ischaemia-Reperfusion of Rat Kidneys In Vivo (2000) (0)
P INHIBITION BY PROSTANOID EP RECEPTOR AGONISTS OF FORMYL-METHIONYL-LEUCYL-PHENYLALANINE ( FMLP )-STIMULATED NEUTROPHIL SUPEROXIDE PRODUCTION AND RELATIONSHIP TO INCREASES IN cAMP (2007) (0)
Treatment ofacutemyocardial ischaemia with a selective antagonist ofthromboxane receptors (BM13.177) (1986) (0)
PARP and myocardial ischaemia-reperfusion injury (2003) (0)
Erythropoietin attenuates cardiac injury in experimental sepsis via activation of the beta-common receptor. (2012) (0)
Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale (2019) (0)
Role of tyrosine kinase and NFκB in the induction of nitric oxide synthase by lipoteichoic acid in cultured murine macrophages (1995) (0)
Inducible nitric oxide synthase‐deficient mice exhibit resistance to the acute pancreatitis induced by cerulein.: 243 (2003) (0)
INHIBITION OF GLYCOGEN SYNTHASE KINASE (GSK)-3?? IMPROVES HEPATIC MICROCIRCULATION AFTER HEMORRHAGIC SHOCK (2006) (0)
A glycogen synthase kinase-3 inhibitor (TDZD-8) attenuates the liver and neuromuscular injury caused by burn in the rat. (2006) (0)
Erythropoietin reduces the acute kidney injury in experimental sepsis via activation of the beta-common receptor. (2012) (0)
Effect of soluble JAM‐C on leukocyte transmigration in models of ischemia/reperfusion injury (2009) (0)
Increased inotropism following PARP inhibition in the setting of myocardial reperfusion injury: another piece in the jigsaw? (2010) (0)
Endothelin- inhibits platelet aggregation invivo: a study with Hlindium-labelled platelets (1990) (0)
Different Roles for Thromboxane Synthetase Inhibitors and Prostacyclin Mimetics in Myocardial Reperfusion Damage (1985) (0)
Three day pre-treatment with erythropoietin attenuates the orgain injury and dysfunction induced by hemorrhagic shock in the rat by a mechanism independent of endothelial progenitor cell mobilization. (2012) (0)
15‐DEOXY‐DELTA 12,14‐PROSTAGLANDIN J2 REDUCES THE MULTIPLE ORGAN INJURY/DYSFUNCTION IN ENDOTOXIC SHOCK: 503 (2004) (0)
Effects of 5-AIQ on the multiple organ failure associated to thermal injury in the rat (2003) (0)
SYNTHETIC CPG- AND GPC OLIGODEOXYNUCLEOTIDES ENHANCE THE TNF? RELEASE INDUCED BY PEPTIDOGLYCAN BUT NOT BY LIPOPOLYSACCHARIDE: 69 (2004) (0)
Enhanced sphingosine-1-phosphate levels ameliorate murine septic cardiomyopathy (2015) (0)
THE EFFECT OF SIMVASTATTN PRE-TREATMENT IN AN EXPERIMENTAL MODEL OF BURN INJURY IN THE RAT (2009) (0)
EFFECTS OF GW274150, A NOVEL AND POTENT iNOS‐INHIBITOR ON THE MULTIPLE ORGAN INJURY IN HEMORRHAGIC SHOCK IN THE ANESTHETISED RAT.: 153 (2003) (0)
POLY (ADP‐RIBOSE) POLYMERASE (PARP) AND ISCHEMIA‐ REPERFUSION INJURY: 357 (2004) (0)
INFLUENCE OF LIVER X RECEPTOR SIGNALING ON SEPTIC PATHOLOGY (2006) (0)
The effect of 5-aminoisoquinolinone during machine perfusion of kidneys recovered after cardiac death (Experimental study) (2008) (0)
Intracellular release of PAF contributes to the induction of nitric oxide synthase in a model of gram-positive shock (1995) (0)
Oxygen in the Heart: How Much is too Much? (2017) (0)
Thecontribution oftumournecrosis factor-a andendothelin- 1 to theincrease ofcoronaryresistance inhearts fromratstreated with endotoxin (1995) (0)
Role of chelatable iron versus myoglobin in oxidative stress after crush trauma. (2009) (0)
WHAT'S NEW IN SHOCK, MAY 2006 (2006) (0)
reduction ofmyocardial infarct size inthe rabbit byactivation ofATP-sensitive potassium channels (1996) (0)
Evidence fromreceptor antagonists ofan important role for ETBreceptor-mediate d vasoconstrictor effects ofendothelin-1 in theratkidney (1994) (0)
The role of hydrogen sulphide in ischaemia/reperfusion injury of the rat kidney (2007) (0)
SYSTEMIC PETIDOGLYCAN (PEPG) STIMULATES PROINFLAMMATORY RESPONSES IN SYNERGY WITH LIPOPOLYSACCHARIDE (LPS) IN AN IN VIVO AND IN VITRO PORCINE MODEL (2006) (0)
Inhibitors of poly(ADP-ribose) polymerase activity as interventions against renal ischemia/reperfusion injury and acute renal failure (2003) (0)
LACK OF EFFECT OF ERYTHROPOIETIN (EPO) ON RENAL OR LIVER FAILURE IN ENDOTOXIC SHOCK IN THE RAT.: 118 (2003) (0)
Tyrphostin AG126 reduces ischemia-reperfusion injury of the liver in the rat. (2005) (0)
Relaxin Activates theL-Arginine–Nitric Oxide Pathway in Vascular Smooth Muscle Cells in Culture (1998) (0)
Abstract 1741: Bone Marrow Mononuclear Cell Therapy upon Reperfusion Reduces Myocardial Infarct Size by Activating the PI3K/Akt Survival Pathway (2008) (0)
A vaccine to prevent infections with Staphylococcus aureus. (2002) (0)
N omega nitro l arginine and n omega nitro l arginyl l phenylalanine inhibit endothelium dependent vasodilatations in vitro in rabbits and in vivo in the anesthetized rat (1990) (0)
Activation of Ppar-beta/delta attenuates mycardial ischemia/reperfusion injury in the rat (2009) (0)
Roleoftumour necrosis factor intheinduction ofnitric oxide synthase inaratmodelofendotoxin shock (1993) (0)
INOS INHIBITORS FOR THE THERAPY OF SHOCK AND ORGAN INJURY: 501 (2004) (0)
Inflammatory signaling and insulin resistance caused by sugar intake: modulation by PPAR-δ agonism (2013) (0)
The Potential Impact of Heparanase Activity and Endothelial Damage in COVID-19 Disease (2022) (0)
multiple organ dysfunction by 1-amino-2-hydroxy-guanidine, apotent inhibitor ofinducible nitric oxide synthase (1996) (0)
CYTOKINE RESPONSES TO COMBINED ADMINISTRATION OF LIPOPOLYSACCHARIDE (LPS) AND PEPTIDOGLYCAN (PEPG): 197 (2004) (0)
inhibition oftheexpression of inducible nitric oxide synthase incultured macrophages and intheanaesthetized rat (1995) (0)
ACTIVATION OF LIVER X RECEPTOR BY SYNTHETIC AGONIST T0901317 REDUCES THE LIVER INJURY CAUSED BY LIPOPOLYSACCHARIDE IN THE RAT: A NOVEL PRINCIPLE FOR TREATMENT OF SEPSIS AND SHOCK (2006) (0)
Tissue Protective Activities of Erythropoietin (2010) (0)
Effects oftheendothelin receptorantagonist, SB209670, on circulatory failure andorgan injury inendotoxic shockinthe anaesthetized rat (1996) (0)
Nitric Oxide, Systemic Inflammatory Response Syndrome and Circulatory Shock (1999) (0)
Insulin and TDZD-8, a glycogen synthase kinase-3 beta inhibitor, reduce the liver injury caused by ischemia-reperfusion in the rat (2008) (0)
Thiamine protects the kidney against the injury and dysfunction caused by ischaemia reperfusion by multiple mechanisms (2010) (0)
EFFECT OF RECOMBINANT HUMAN ERYTHROPOIETIN IN A RAT MODEL OF ISCHEMIA‐REPERFUSION INJURY OF THE LIVER: 346 (2004) (0)
Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states (2015) (0)
Cardioprotective effects of prostaglandin E1 in the rabbit are abolished by a blocker of ATP-sensitive potassium channels (1995) (0)
Tyrosine kinase is essential for induction of COX-2 in endothelial cells by LPS or inflammatory cytokines (1995) (0)
For Peer Review A nonerythropoietic peptide derivative of erythropoietin decreases susceptibility to diet-induced insulin resistance in mice. (2014) (0)
ACTIVATION OF THE LIVER X RECEPTOR BY GW3965 PROTECTS AGAINST HEPATIC INJURY IN ENDOTOXEMIA.: 121-T (2005) (0)
Endothelium-derived mediators and the control of the vascular system. (1991) (0)
THE RADICAL SCAVENGER TEMPONE REDUCES THE ACTIVATION OF AP‐1 AND THE RENAL AND LIVER INJURY CAUSED BY HEMORRHAGIC SHOCK IN THE ANESTHETIZED RAT.: 133 (2003) (0)
Combined Use of Nitric Oxide and Nitric Oxide Synthase Inhibitors as a Possible Therapeutic Approach (2000) (0)
What's New In shock , June 2007 (2007) (0)
PEPTIDOGLYCAN CAUSES LOCAL AND SYSTEMIC INFLAMMATION IN THE RAT: 591 (2004) (0)
The Response to the Letter to the Editor Titled: "Is Triple Self-plagiarism "OK" If Only Made Transparent?" by Volker R Jacobs, MD, MBA. (2019) (0)
Protective effects of a PPAR-δ agonist and a non-erythropoietic peptide derivative of erythropoietin against the diet-induced development of skeletal muscle insulin resistance and inflammation in mice (2015) (0)
THE ROLE OF iNOS FOR HEPATIC GLUCOSE PRODUCTION IN MURINE SEPTIC SHOCK (2006) (0)
What's new in shock, May 2007? (2007) (0)
The effect of uraemia on the duration of arrhythmias in the context of cardioprotective ischaemic conditioning strategies (2014) (0)
Identification of an endogenous cardioprotective pathway involving 12‐lipoxygenase (12‐LOX), C‐fibers and the non‐selective cation channel TRPV1 (2006) (0)
Effects of tempol, a membrane-permeable radical scavenger, in a rodent model of collagen-induced arthritis: 198 (1999) (0)
Programme and Abstracts (2001) (0)
Abstract 10249: Differential Regulation of Neutrophil Mobilization and Integrin Expression in Females Protects Against Ischemia/Reperfusion-Induced Local and Remote Tissue Injury (2011) (0)
The selective PPARgamma antagonist GW9662 abolished the protection afforded by LPS-pretreatment in a rat model of renal ischemia/reperfusion injury (2005) (0)
WHAT'S NEW IN SHOCK, October 2007? (2007) (0)
THE EFFECT OF 5-AIQ ON THE LIVER ISCHAEMIA/REPERFUSION INJURY: 62 (2002) (0)
ROLE OF POLY (ADP‐RIBOSE) POLYMERASE (PARP) IN THE DEVELOPMENT OF RENAL ISCHAEMIA‐REPERFUSION INJURY: 363 (2004) (0)
Mandarin Translations (2010) (0)
Vascular hyporeactivity tovasoconstrictor agents andhemodynamic decompensation inhemorrhagic shockismediated bynitric oxide (1993) (0)
Artesunate Protects Against the Organ Injury and Hemorrhage and Resuscitation Dysfunction Induced by Severe (2016) (0)
Evidence for the role of PPAR‐β/δ in the development of spinal cord injury (2010) (0)
Formyl peptide receptor type 2 (FPR2) deficiency in myeloid cells amplifies sepsis-induced cardiac dysfunction. (2023) (0)
A SUPEROXIDE DISMUTASE MIMETIC WITH CATALASE ACTIVITY (EUK 8) AMELIORATES THE ACUTE LIVER FAILURE IN A MODEL OF GRAM-POSITIVE BACTERIAL SHOCK IN THE RAT.: 75 (2002) (0)
PARP Inhibitors and Cardioprotection (2002) (0)
What's new in Shock, April 2008? (2008) (0)
TRAUMA ORGAN PROTECTION WITH ARTESUNATE (TOP-ART): PRECLINICAL EFFICACY OF AN ANTIMALARIAL DRUG WITH EXCELLENT SAFETY PROFILE AND PLANNED PHASE II RCT. (2015) (0)
Erythropoietic Stimulating Agents (2013) (0)
Response to Letter Regarding Article, “Ischemic Conditioning Protects the Uremic Heart in a Rodent Model of Myocardial Infarction” (2012) (0)
Bruton’s tyrosine kinase inhibition attenuates disease progression by reducing renal immune cell invasion in mice with hemolytic-uremic syndrome (2023) (0)
A nonerythropoietic peptide analog of erythropoietin decreases susceptibility to diet-induced insulin resistance (2013) (0)
Delayed circulatory failure duetotheinduction ofnitric oxide synthase bylipoteichoic acidfromStaphylococcus aureusinanaesthetized rats (1995) (0)
Inhibition of endogenous hydrogen sulphide formation protects the liver from scald burn injury in the rat (2007) (0)
Nutritional support in critically ill patients: enteral, parenteral, or not at all? (2014) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Christopher Thiemermann?

Christopher Thiemermann is affiliated with the following schools:

Christopher Thiemermann's Academic­Influence.com Rankings

Christopher Thiemermann's Degrees

Why Is Christopher Thiemermann Influential?

Christopher Thiemermann's Published Works

Published Works

What Schools Are Affiliated With Christopher Thiemermann?

Christopher Thiemermann's AcademicInfluence.com Rankings