Christos Ouzounis
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Greek biologist
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Bioinformatics
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Biology
Why Is Christos Ouzounis Influential?
(Suggest an Edit or Addition)According to Wikipedia, Christos A. Ouzounis is a computational biologist, a director of research at the CERTH, and Professor of Bioinformatics at Aristotle University in Thessaloniki. Education Ouzounis received his undergraduate degree in Biological Sciences from the Aristotle University of Thessaloniki in 1987. He then received an M.Sc. in Biological Computation from the University of York in 1988 and went on to perform doctoral work with Chris Sander at the European Molecular Biology Laboratory in Heidelberg, Germany receiving his PhD from the University of York in 1993.
Christos Ouzounis's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- An efficient algorithm for large-scale detection of protein families. (2002) (3370)
- Protein interaction maps for complete genomes based on gene fusion events (1999) (1122)
- Expansion of the BioCyc collection of pathway/genome databases to 160 genomes (2005) (669)
- Automatic Extraction of Biological Information from Scientific Text: Protein-Protein Interactions (1999) (511)
- Detection of functional modules from protein interaction networks (2003) (445)
- Are splicing mutations the most frequent cause of hereditary disease? (2005) (371)
- Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis. (2007) (358)
- Genome-wide identification of genes likely to be involved in human genetic disease. (2004) (277)
- Comparative genomics of transcriptional control in the human malaria parasite Plasmodium falciparum. (2004) (272)
- The net of life: reconstructing the microbial phylogenetic network. (2005) (266)
- A database of protein structure families with common folding motifs (1992) (224)
- Automated genome sequence analysis and annotation (1999) (219)
- GeneRAGE: a robust algorithm for sequence clustering and domain detection (2000) (212)
- Conserved Clusters of Functionally Related Genes in Two Bacterial Genomes (1997) (209)
- The balance of driving forces during genome evolution in prokaryotes. (2003) (205)
- Transcription regulation and environmental adaptation in bacteria. (2003) (196)
- Genomic Encyclopedia of Bacteria and Archaea: Sequencing a Myriad of Type Strains (2014) (195)
- BioLayout-an automatic graph layout algorithm for similarity visualization (2001) (177)
- Modeling the percolation of annotation errors in a database of protein sequences (2002) (176)
- Identification of thermophilic species by the amino acid compositions deduced from their genomes. (2001) (175)
- CAST: an iterative algorithm for the complexity analysis of sequence tracts (2000) (171)
- DisProt: intrinsic protein disorder annotation in 2020 (2019) (154)
- Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes (2006) (154)
- Genome evolution reveals biochemical networks and functional modules (2003) (152)
- Emergence, development and diversification of the TGF-β signalling pathway within the animal kingdom (2009) (145)
- Protein families and TRIBES in genome sequence space. (2003) (143)
- KOW: a novel motif linking a bacterial transcription factor with ribosomal proteins. (1996) (138)
- A minimal estimate for the gene content of the last universal common ancestor--exobiology from a terrestrial perspective. (2006) (138)
- TEXTQUEST: Document Clustering of MEDLINE Abstracts For Concept Discovery In Molecular Biology (2000) (130)
- Early bioinformatics: the birth of a discipline - a personal view (2003) (126)
- Functional associations of proteins in entire genomes by means of exhaustive detection of gene fusions (2001) (125)
- Classification schemes for protein structure and function (2003) (122)
- The past, present and future of genome-wide re-annotation (2002) (113)
- Universal Protein Families and the Functional Content of the Last Universal Common Ancestor (1999) (106)
- GeneQuiz: A Workbench for Sequence Analysis (1994) (103)
- A global metagenomic map of urban microbiomes and antimicrobial resistance (2021) (102)
- Global properties of the metabolic map of Escherichia coli. (2000) (101)
- The phylogenetic extent of metabolic enzymes and pathways. (2003) (97)
- Prediction of protein interactions: metabolic enzymes are frequently involved in gene fusion (2000) (97)
- Structural and functional properties of genes involved in human cancer (2006) (91)
- Evaluation of annotation strategies using an entire genome sequence (2003) (86)
- Prediction of Enzyme Classification from Protein Sequence without the Use of Sequence Similarity (1997) (83)
- Transcription in archaea. (1999) (82)
- HipMCL: a high-performance parallel implementation of the Markov clustering algorithm for large-scale networks (2018) (81)
- Percolation of annotation errors through hierarchically structured protein sequence databases. (2005) (78)
- An updated metabolic view of the Bacillus subtilis 168 genome. (2013) (77)
- EUCLID: automatic classification of proteins in functional classes by their database annotations (1998) (73)
- Functional evolution of the yeast protein interaction network. (2004) (72)
- TFIIB, an evolutionary link between the transcription machineries of archaebacteria and eukaryotes (1992) (71)
- Myriads of protein families, and still counting (2003) (70)
- Tumorigenic Properties of Iron Regulatory Protein 2 (IRP2) Mediated by Its Specific 73-Amino Acids Insert (2010) (68)
- Whole‐genome sequence annotation: ‘Going wrong with confidence’ (1999) (66)
- HinCyc: A Knowledge Base of the Complete Genome and Metabolic Pathways of H. influenzae (1996) (66)
- Rise and Demise of Bioinformatics? Promise and Progress (2012) (65)
- Dictionary building via unsupervised hierarchical motif discovery in the sequence space of natural proteins (1999) (65)
- Genome sequences and great expectations (2000) (62)
- From genome sequences to protein function (1994) (62)
- BioLayout(Java): versatile network visualisation of structural and functional relationships. (2005) (61)
- A Systems Model for Immune Cell Interactions Unravels the Mechanism of Inflammation in Human Skin (2010) (60)
- Disentangling the complexity of low complexity proteins (2019) (60)
- Measuring genome conservation across taxa: divided strains and united kingdoms (2005) (59)
- Transcriptome classification reveals molecular subtypes in psoriasis (2012) (59)
- Recent developments and future directions in computational genomics (2000) (59)
- Sequence-based feature prediction and annotation of proteins (2009) (59)
- Highly consistent patterns for inherited human diseases at the molecular level (2006) (56)
- Strain-specific genes of Helicobacter pylori: distribution, function and dynamics. (2001) (56)
- GeneTRACE - Reconstruction of Gene Content of Ancestral Species (2003) (54)
- On the evolution of arginases and related enzymes (1994) (52)
- PuReD-MCL: a graph-based PubMed document clustering methodology (2008) (51)
- An exponential core in the heart of the yeast protein interaction network. (2005) (50)
- From genes to genomes: universal scale-invariant properties of microbial chromosome organisation. (2003) (47)
- The phylogenetic diversity of eukaryotic transcription. (2003) (45)
- No wisdom in the crowd: genome annotation in the era of big data – current status and future prospects (2018) (43)
- The eubacterial transcriptional activator Lrp is present in the archaeon Pyrococcus furiosus. (1995) (43)
- A structure‐derived sequence pattern for the detection of type I copper binding domains in distantly related proteins (1991) (43)
- COmplete GENome Tracking (COGENT): A Flexible Data Environment for Computational Genomics (2003) (42)
- What's in a genome? (1992) (42)
- Automated metabolic reconstruction for Methanococcus jannaschii. (2004) (40)
- Computational complexity of algorithms for sequence comparison, short-read assembly and genome alignment (2017) (40)
- Toward unrestricted use of public genomic data (2019) (40)
- Genome coverage, literally speaking (2005) (39)
- Functional versatility and molecular diversity of the metabolic map of Escherichia coli. (2001) (36)
- Proceedings of the 5th International Conference on Intelligent Systems for Molecular Biology (1996) (36)
- Maps, books and other metaphors for systems biology. (2006) (36)
- DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation (2021) (34)
- Taxonomic Identification of Mediterranean Pines and Their Hybrids Based on the High Resolution Melting (HRM) and trnL Approaches: From Cytoplasmic Inheritance to Timber Tracing (2013) (34)
- Computational comparisons of model genomes. (1996) (33)
- Probabilistic annotation of protein sequences based on functional classifications (2005) (33)
- Analysis of the Thermotoga maritima genome combining a variety of sequence similarity and genome context tools. (2000) (31)
- Beyond 100 genomes (2003) (31)
- Annotation inconsistencies beyond sequence similarity-based function prediction – phylogeny and genome structure (2015) (30)
- Genome coverage, literally speaking. The challenge of annotating 200 genomes with 4 million publications. (2005) (28)
- Comparison of sequence masking algorithms and the detection of biased protein sequence regions (2003) (26)
- CoGenT++: an extensive and extensible data environment for computational genomics (2005) (26)
- Sequence analysis of the Methanococcus jannaschii genome and the prediction of protein function (1997) (25)
- Gene Network and Proteomic Analyses of Cardiac Responses to Pathological and Physiological Stress (2013) (25)
- BioTextQuest+: a knowledge integration platform for literature mining and concept discovery (2014) (24)
- Transcription-associated protein families are primarily taxon-specific (2001) (24)
- Genomes with distinct function composition (1996) (24)
- Genome-wide expression patterns in physiological cardiac hypertrophy (2010) (24)
- Genequiz II: Automatic Function Assignment For Genome Sequence Analysis (1996) (23)
- Bioinformatics and the theoretical foundations of molecular biology (2002) (23)
- Denoising inferred functional association networks obtained by gene fusion analysis (2007) (23)
- A path towards SARS-CoV-2 attenuation: metabolic pressure on CTP synthesis rules the virus evolution (2020) (22)
- MagicMatch - cross-referencing sequence identifiers across databases (2005) (22)
- Biological information extraction and co-occurrence analysis. (2014) (22)
- Atypical Divergence of SARS-CoV-2 Orf8 from Orf7a within the Coronavirus Lineage Suggests Potential Stealthy Viral Strategies in Immune Evasion (2021) (22)
- Errors in Genome Reviews (1998) (22)
- Functional Genomics Assistant (FUGA): a toolbox for the analysis of complex biological networks (2011) (21)
- Ready for a motif submission? A proposed checklist. (1995) (21)
- Functional Genomics Evidence Unearths New Moonlighting Roles of Outer Ring Coat Nucleoporins (2014) (21)
- Clustering the annotation space of proteins (2005) (20)
- CORRIE: enzyme sequence annotation with confidence estimates (2007) (19)
- Two or three myths about bioinformatics (2000) (19)
- Metabolic innovations towards the human lineage (2008) (18)
- Genome‐wide detection and family clustering of ion channels (2002) (18)
- Orthology: another terminology muddle. (1999) (18)
- Detection of Genomic Idiosyncrasies Using Fuzzy Phylogenetic Profiles (2013) (18)
- Genetic variation between Helicobacter pylori strains: gene acquisition or loss? (2002) (18)
- Experimental evidence validating the computational inference of functional associations from gene fusion events: a critical survey (2012) (18)
- Ancestral state reconstructions for genomes. (2005) (17)
- Critical assessment of protein intrinsic disorder prediction (2021) (17)
- Mechanisms of specificity in mRNA degradation: autoregulation and cognate interactions. (1993) (16)
- BioTextQuest: a web-based biomedical text mining suite for concept discovery (2011) (15)
- Parallel origins of the nucleosome core and eukaryotic transcription from Archaea (1996) (15)
- The properties of protein family space depend on experimental design (2005) (15)
- Stratification of hospitalized COVID-19 patients into clinical severity progression groups by immuno-phenotyping and machine learning (2022) (15)
- Copy Number and Loss of Heterozygosity Detected by SNP Array of Formalin-Fixed Tissues Using Whole-Genome Amplification (2011) (14)
- Lineage-specific partitions in archaeal transcription. (2007) (14)
- Reproducibility in genome sequence annotation: the Plasmodium falciparum chromosome 2 case (1999) (13)
- A recent origin of Orf3a from M protein across the coronavirus lineage arising by sharp divergence (2020) (13)
- A Strong Seasonality Pattern for Covid-19 Incidence Rates Modulated by UV Radiation Levels (2021) (13)
- The Chlamydiales Pangenome Revisited: Structural Stability and Functional Coherence (2012) (12)
- An intrinsically disordered proteins community for ELIXIR (2019) (11)
- A Drosophila hsp70 gene contains long, antiparallel, coupled open reading frames (LAC ORFs) conserved in homologous loci (1995) (11)
- Promoter Complexity and Tissue-Specific Expression of Stress Response Components in Mytilus galloprovincialis, a Sessile Marine Invertebrate Species (2010) (11)
- Kernel Projection of Latent Structures Regression for Facial Animation Retargeting (2017) (11)
- Sequence evidence for common ancestry of eukaryotic endomembrane coatomers (2015) (10)
- Metabolic database systems for the analysis of genome‐wide function (2003) (10)
- Nucleic acid-binding metabolic enzymes: Living fossils of stereochemical interactions? (1995) (9)
- PseuRECA: genome annotation and gene context analysis for Pseudomonas aeruginosa PAO1 (2003) (9)
- Sensitive detection of sequence similarity using combinatorial pattern discovery: A challenging study of two distantly related protein families (2005) (9)
- Bacterial sigma 70 transcription factor DNA-binding domains in the archaeon Methanococcus jannaschii. (1997) (9)
- A ferredoxin-like domain in RNA polymerase 30/40-kDa subunits. (1998) (9)
- The Emergence of Bioinformatics: Historical Perspective, Quick Overview and Future Trends (2009) (8)
- Stratification of co-evolving genomic groups using ranked phylogenetic profiles (2009) (8)
- ThiD-TenA: A Gene Pair Fusion in Eukaryotes (1997) (8)
- Mapping Functional Associations in the Entire Genome of Drosophila melanogaster Using Fusion Analysis (2003) (7)
- Assessment for the seasonality of Covid-19 should focus on ultraviolet radiation and not ‘warmer days’ (2020) (7)
- The bioinformatics wealth of nations (2020) (6)
- Assessing Proteinase K Resistance of Fish Prion Proteins in a Scrapie-Infected Mouse Neuroblastoma Cell Line (2014) (6)
- Novel coding regions in four complete archaeal genomes. (1999) (6)
- Reverse interpretation: a hypothetical selection mechanism for adaptive mutagenesis based on autoregulated mRNA stability. (1994) (6)
- Faculty Opinions recommendation of Pathway databases: a case study in computational symbolic theories. (2001) (5)
- Automated Genome Functional Annotation for Structural Genomics (2002) (5)
- Using Personalized Finger Gestures for Navigating Virtual Characters (2015) (5)
- Preliminary evidence for seasonality of Covid-19 due to ultraviolet radiation (2020) (5)
- Robustness of Metabolic Map Reconstruction (2004) (5)
- Faculty Opinions recommendation of Metagenes and molecular pattern discovery using matrix factorization. (2004) (4)
- Consent insufficient for data release—Response (2019) (4)
- BioPAXViz: a cytoscape application for the visual exploration of metabolic pathway evolution (2017) (4)
- Ancestral state reconstruction of metabolic pathways across pangenome ensembles (2020) (3)
- The Functional Composition of Living Machines as a Design Principle for Artificial Organisms (1995) (3)
- Science communication media for scientists and the public (2007) (3)
- Developing computational biology at meridian 23° E, and a little eastwards (2018) (3)
- Brain Radiation Information Data Exchange (BRIDE): integration of experimental data from low-dose ionising radiation research for pathway discovery (2016) (3)
- Spatial Structure of Evolutionary Models of Dialects in Contact (2015) (3)
- BioTextQuest+: a knowledge integration platform for literature mining and concept discovery. (2015) (3)
- Establishment of computational biology in Greece and Cyprus: Past, present, and future (2019) (3)
- H3ABioNet computational metagenomics workshop in Mauritius: training to analyse microbial diversity for Africa (2015) (2)
- Understanding Specialized Ribosomal Protein Functions and Associated Ribosomopathies by Navigating Across Sequence, Literature, and Phenotype Information Resources (2019) (2)
- Bioinformatics computation of metabolic models from sequenced genomes (2015) (2)
- Immunophenotyping and machine learning identify distinct immunotypes that predict COVID-19 clinical severity (2021) (2)
- Hypothesis, analysis and synthesis, it's all Greek to me (2019) (2)
- Meeting Report: The Seventh Conference of the Hellenic Society for Computational Biology and Bioinformatics (2013) (2)
- Protein coalitions in a core mammalian biochemical network linked by rapidly evolving proteins (2011) (2)
- The Coming of Age for Big Data in Systems Radiobiology, an Engineering Perspective (2020) (2)
- Computational analysis of metabolic networks (2008) (2)
- A history of the MetaSUB consortium: Tracking urban microbes around the globe (2022) (2)
- 138 FUNCTIONAL GENOMICS: REVISITING THE LINK BETWEEN SCOLIOSIS AND CONGENITAL HEART DISEASE (2011) (1)
- Transcriptome classification reveals molecular subtypes in psoriasis (2012) (1)
- Sequence variation, common tissue expression patterns and learning models: a genome-wide survey of vertebrate ribosomal proteins (2020) (1)
- BioPAXViz: a cytoscape application for the visual exploration of metabolic pathway evolution. (2017) (1)
- PLOS Computational Biology 2017 Reviewer and Editorial Board Thank You (2018) (1)
- Hypothesis, analysis and synthesis: it’s all Greek to me! (2019) (1)
- The core histone fold: Limits to functional versatility (1996) (1)
- An intrinsically disordered proteins community for ELIXIR [version 1; peer review: 2 approved] (2020) (1)
- Annotating unknown species of urban microorganisms on a global scale unveils novel functional diversity and local environment association. (2021) (1)
- The comparative genomics of protein interactions. (2007) (1)
- Protein Structure. Determination, Analysis, and Applications for Drug Discovery (Chasman, D. I., ed., Marcel Dekker, New York-Basel, 2003, 606 p., $195) (2004) (1)
- Multi-genome Core Pathway Identification through Gene Clustering (2012) (1)
- Computational Analysis of Biochemical Networks for Genome Evolution and Functional Association (2005) (0)
- Travelling to scientific meetings is a mission, not a vacation (2020) (0)
- The quest for an upper limit in systems biology (2012) (0)
- Properties of Genes involved in Human Genetic Disease (2004) (0)
- H3ABioNet computational metagenomics workshop in Mauritius: training to analyse microbial diversity for Africa (2015) (0)
- Faculty Opinions recommendation of Identification of functional links between genes using phylogenetic profiles. (2004) (0)
- A library of sensitive position-specific scoring matrices for high-throughput identification of nuclear pore complex subunits (2023) (0)
- Contributors (2019) (0)
- Inference of Pathway Decomposition Across Multiple Species Through Gene Clustering (2015) (0)
- SONNHAMMER reading frames of yeast chromosome III Comprehensive sequence analysis of the 182 predicted open (2002) (0)
- Proceedings of the 5th International Conference on Intelligent Systems for Molecular Biology, Halkidiki, Greece, June 21-26, 1997 (1997) (0)
- A Million Annotations for the Molecular Biologist (2000) (0)
- BRIDE v2: A Validated Collection of Genes Involved in the Mammalian Brain Response to Low-Dose Ionizing Radiation (2022) (0)
- Standardisation in life-science research - Making the case for harmonization to improve communication and sharing of data amongst researchers (2018) (0)
- Faculty Opinions recommendation of [CONFERENCE POSTER]: Frequency of INherited Disorders database (FINDbase): A web application reporting genetic variation allele frequencies worldwide. (2011) (0)
- CHAPTER 6 . 1 Computational analysis of metabolic networks (0)
- Commentary response (2001) (0)
- Molecular and Functional Plasticity in the Escherichia coli Metabolic Map (2001) (0)
- Disease association and comparative genomics of compositional bias in human proteins (2023) (0)
- Function Assignment in Complete Genomes (2000) (0)
- Faculty Opinions recommendation of Identifying functional links between genes using conserved chromosomal proximity. (2003) (0)
- Faculty Opinions recommendation of Universal trees based on large combined protein sequence data sets. (2001) (0)
- Phylogenetic Conservation of Metabolic Enzymes and Pathways (2004) (0)
- Faculty Opinions recommendation of The genome reduction hypothesis and the phylogeny of eukaryotes. (2004) (0)
- Faculty Opinions recommendation of Domains, motifs and clusters in the protein universe. (2004) (0)
- Faculty Opinions recommendation of Application of compression-based distance measures to protein sequence classification: a methodological study. (2007) (0)
- Protein interactionmaps forcomplete genomesbasedongenefusionevents (1999) (0)
- Mining the Rhodopseudomonas palustris Genome for Hydrogen Siv Andersson : Phylogeny and Diversity of Vector-Borne Pathogens : What to Expect from Genomics and Microarray Technologies ? (2006) (0)
- Faculty Opinions recommendation of Analyzing yeast protein-protein interaction data obtained from different sources. (2003) (0)
- Faculty Opinions recommendation of [CONFERENCE POSTER]: The complete genomes of three ethanol-producing Zymomonas mobilis strains: Insights in comparative genomics. (2011) (0)
- Molecular and Functional Diversity of Biochemical Pathwayas (2001) (0)
- Disease association and comparative genomics of compositional bias in human proteins. (2023) (0)
- Genome Sequencing & Comparative Analysis (2002) (0)
- Developing computational biology at meridian 23° E, and a little eastwards (2018) (0)
- IDENTIFICATION OF CANDDATE GENES (2017) (0)
- Faculty Opinions recommendation of Combinatorial synthesis of genetic networks. (2003) (0)
- Prediction of Enzyme Classi cation from Protein Sequence without Homology (1998) (0)
- THE COMPARATIVE GENOMICS OF PROTEIN INTERACTIONS (2007) (0)
- Protein Structure. Determination, Analysis, and Applications for Drug Discovery (Chasman, D. I. (ed.), Marcel Dekker, New York-Basel, 2003, 606 p., $195) (2004) (0)
- The machinery of life (1993) (0)
- Brain Radiation Information Data Exchange (BRIDE): integration of experimental data from low-dose ionising radiation research for pathway discovery (2016) (0)
- Stratification of hospitalized COVID-19 patients into clinical severity progression groups by immuno-phenotyping and machine learning (2022) (0)
- Structure, Function and Evolution of Y-Nucleoporins and Eukaryotic Coatomer Components Using Sequence Space Walks and Tissue-Specific Expression Patterns (2016) (0)
- Lawrence Berkeley National Laboratory Recent Work Title HipMCL : a high-performance parallel implementation of the Markov clustering algorithm for large-scale networks (2018) (0)
- Keynote lectures (2022) (0)
- Clustering of discrete and fuzzy phylogenetic profiles (2010) (0)
- Faculty Opinions recommendation of Trends between gene content and genome size in prokaryotic species with larger genomes. (2004) (0)
- Annotation inconsistencies beyond sequence similarity-based function prediction – phylogeny and genome structure (2015) (0)
- Faculty Opinions recommendation of In silico two-hybrid system for the selection of physically interacting protein pairs. (2003) (0)
- Evolutionary Aspects of Selenium Binding Protein (SBP). (2023) (0)
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What Schools Are Affiliated With Christos Ouzounis?
Christos Ouzounis is affiliated with the following schools:
