Christos Socrates Mantzoros
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(Suggest an Edit or Addition)According to Wikipedia, Christos Socrates Mantzoros is a Greek American physician-scientist, practicing internist-endocrinologist, teacher and researcher. He is a professor of medicine at Harvard Medical School and an adjunct professor at Boston University School of Medicine. He currently serves as the chief of endocrinology, diabetes and metabolism at the VA Boston Healthcare System, where he created de novo a leading academic division true to its tripartite mission and as the founding director of human nutrition at Beth Israel Deaconess Medical Center , Harvard Medical School. Finally, he holds the editor-in-chief position of the journal Metabolism: Clinical and Experimental.
Christos Socrates Mantzoros's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Role of leptin in the neuroendocrine response to fasting (1996) (3087)
- Adverse metabolic and cardiovascular consequences of circadian misalignment (2009) (1818)
- FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. (2012) (887)
- Diabetes mellitus and risk of breast cancer: A meta‐analysis (2007) (782)
- Mediterranean diet and incidence and mortality of coronary heart disease and stroke in women (2009) (735)
- Human leptin levels are pulsatile and inversely related to pituitary–ardenal function (1997) (670)
- The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men. (2003) (592)
- Severe obesity, increasing age and male sex are independently associated with worse in-hospital outcomes, and higher in-hospital mortality, in a cohort of patients with COVID-19 in the Bronx, New York (2020) (579)
- Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration: cross-sectional and interventional studies in normal, insulin-resistant, and diabetic subjects. (2003) (568)
- The Role of Leptin in Human Obesity and Disease: A Review of Current Evidence (1999) (566)
- Obesity and cancer risk: Emerging biological mechanisms and perspectives. (2019) (545)
- Narrative Review: The Role of Leptin in Human Physiology: Emerging Clinical Applications (2010) (544)
- The role of adiponectin in cancer: a review of current evidence. (2012) (536)
- Adiponectin and breast cancer risk. (2004) (532)
- Leptin and reproduction: a review. (2002) (528)
- Dietary Patterns and Risk of Mortality From Cardiovascular Disease, Cancer, and All Causes in a Prospective Cohort of Women (2008) (518)
- A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. V. Rising leptin levels may signal the onset of puberty. (1997) (500)
- Leptin in human physiology and pathophysiology. (2011) (494)
- Effects of protease inhibitors on hyperglycemia, hyperlipidemia, and lipodystrophy: a 5-year cohort study. (2000) (479)
- Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study. (2005) (479)
- Diabetes mellitus and risk of endometrial cancer: a meta-analysis (2007) (476)
- Obesity and nonalcoholic fatty liver disease: From pathophysiology to therapeutics. (2019) (463)
- Adiponectin and cancer: a systematic review (2006) (463)
- Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans. (2003) (450)
- Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance. (2003) (444)
- Serum adiponectin levels are inversely associated with overall and central fat distribution but are not directly regulated by acute fasting or leptin administration in humans: cross-sectional and interventional studies. (2003) (439)
- Circulating irisin in relation to insulin resistance and the metabolic syndrome. (2013) (435)
- Circulating adiponectin and resistin levels in relation to metabolic factors, inflammatory markers, and vascular reactivity in diabetic patients and subjects at risk for diabetes. (2004) (422)
- Leptin in Immunology1 (2005) (402)
- Physiology and role of irisin in glucose homeostasis (2017) (379)
- Adiponectin in insulin resistance: lessons from translational research. (2010) (372)
- Drug Insight: the role of leptin in human physiology and pathophysiology—emerging clinical applications (2006) (363)
- Severe obesity is associated with higher in-hospital mortality in a cohort of patients with COVID-19 in the Bronx, New York (2020) (357)
- The Role of the IGF System in Cancer: From Basic to Clinical Studies and Clinical Applications (2002) (354)
- Activation of β3 Adrenergic Receptors Suppresses Leptin Expression and Mediates a Leptin-Independent Inhibition of Food Intake in Mice (1996) (349)
- Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence. (2007) (348)
- Diurnal and ultradian dynamics of serum adiponectin in healthy men: comparison with leptin, circulating soluble leptin receptor, and cortisol patterns. (2003) (331)
- Role of leptin in energy-deprivation states: normal human physiology and clinical implications for hypothalamic amenorrhoea and anorexia nervosa (2005) (330)
- Hormonal predictors of prostate cancer: a meta-analysis. (2000) (327)
- Recombinant human leptin in women with hypothalamic amenorrhea. (2004) (325)
- From leptin to other adipokines in health and disease: facts and expectations at the beginning of the 21st century. (2015) (324)
- Non-alcoholic fatty liver disease and dyslipidemia: An update. (2016) (316)
- Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training. (2006) (299)
- Whole-grain, bran, and cereal fiber intakes and markers of systemic inflammation in diabetic women. (2006) (282)
- Plasma adiponectin concentrations and risk of incident breast cancer. (2006) (279)
- Circulating adiponectin and endometrial cancer risk. (2004) (268)
- Exercise-induced irisin secretion is independent of age or fitness level and increased irisin may directly modulate muscle metabolism through AMPK activation. (2014) (267)
- Energy homeostasis, obesity and eating disorders: recent advances in endocrinology. (2004) (264)
- Leptin in human physiology and therapeutics (2010) (261)
- Sleep Loss Reduces Diurnal Rhythm Amplitude of Leptin in Healthy Men (2003) (260)
- Leptin in reproduction (2007) (259)
- The Q223R polymorphism of the leptin receptor gene is significantly associated with obesity and predicts a small percentage of body weight and body composition variability. (2001) (251)
- Leptin Receptor Expression and Signaling in Lymphocytes: Kinetics During Lymphocyte Activation, Role in Lymphocyte Survival, and Response to High Fat Diet in Mice1 (2006) (250)
- Plasma adiponectin concentrations in relation to endometrial cancer: a case-control study in Greece. (2003) (245)
- Cohort profile: project viva. (2015) (244)
- Adipokines in nonalcoholic fatty liver disease. (2016) (243)
- Leptin is an effective treatment for hypothalamic amenorrhea (2011) (241)
- Insulin-like growth factor-I in relation to premenopausal ductal carcinoma in situ of the breast. (1998) (239)
- Cord Blood Leptin and Adiponectin as Predictors of Adiposity in Children at 3 Years of Age: A Prospective Cohort Study (2009) (238)
- Regulation of circulating soluble leptin receptor levels by gender, adiposity, sex steroids, and leptin: observational and interventional studies in humans. (2002) (233)
- Independent circadian and sleep/wake regulation of adipokines and glucose in humans. (2005) (228)
- Leptin concentrations in relation to body mass index and the tumor necrosis factor-α system in humans (1997) (226)
- Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies. (2007) (224)
- Total and High-Molecular-Weight Adiponectin and Resistin in Relation to the Risk for Type 2 Diabetes in Women (2008) (223)
- Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. (2007) (223)
- Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice. (2000) (220)
- Cerebrospinal fluid leptin in anorexia nervosa: correlation with nutritional status and potential role in resistance to weight gain. (1997) (217)
- Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans (2014) (216)
- Leptin: in search of role(s) in human physiology and pathophysiology (1998) (216)
- Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy. (2003) (215)
- Lipodystrophy: pathophysiology and advances in treatment (2011) (214)
- Leptin concentrations in the polycystic ovary syndrome. (1997) (213)
- Effects of acute and chronic administration of the melanocortin agonist MTII in mice with diet-induced obesity. (2002) (210)
- Circulating adiponectin levels are associated with better glycemic control, more favorable lipid profile, and reduced inflammation in women with type 2 diabetes. (2005) (209)
- Synchronicity of frequently sampled thyrotropin (TSH) and leptin concentrations in healthy adults and leptin-deficient subjects: evidence for possible partial TSH regulation by leptin in humans. (2001) (209)
- Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals. (2013) (202)
- The role of leptin in regulating bone metabolism. (2015) (200)
- Sex differences in circulating human leptin pulse amplitude: clinical implications. (1998) (199)
- Adherence to the Mediterranean dietary pattern is positively associated with plasma adiponectin concentrations in diabetic women. (2006) (196)
- Statin treatment and new-onset diabetes: a review of proposed mechanisms. (2014) (193)
- IGF‐I and IGF‐II in relation to colorectal cancer (1999) (192)
- The use of statins alone, or in combination with pioglitazone and other drugs, for the treatment of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and related cardiovascular risk. An Expert Panel Statement. (2017) (192)
- Cord blood leptin and insulin-like growth factor levels are independent predictors of fetal growth. (2001) (191)
- Irisin in patients with nonalcoholic fatty liver disease. (2014) (190)
- Dietary factors in relation to rheumatoid arthritis: a role for olive oil and cooked vegetables? (1999) (189)
- Serum Adiponectin Concentrations and Tissue Expression of Adiponectin Receptors Are Reduced in Patients with Prostate Cancer: A Case Control Study (2007) (187)
- Leptin in humans: lessons from translational research. (2009) (187)
- Leptin concentrations in relation to body mass index and the tumor necrosis factor-alpha system in humans. (1997) (184)
- Circulating leptin in non-alcoholic fatty liver disease: a systematic review and meta-analysis (2015) (178)
- Leptin: its role in obesity and beyond (1997) (174)
- Obesity as a Disease. (2018) (174)
- Management of the metabolic syndrome and type 2 diabetes through lifestyle modification. (2009) (171)
- Plasma irisin levels progressively increase in response to increasing exercise workloads in young, healthy, active subjects. (2014) (171)
- Sex Disparities in the Treatment and Control of Cardiovascular Risk Factors in Type 2 Diabetes (2008) (167)
- Pharmacological concentrations of irisin increase cell proliferation without influencing markers of neurite outgrowth and synaptogenesis in mouse H19-7 hippocampal cell lines. (2013) (166)
- Zinc may regulate serum leptin concentrations in humans. (1998) (166)
- Diabetes and Risk of Endometrial Cancer: A Population-Based Prospective Cohort Study (2007) (164)
- Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans. (2006) (164)
- Irisin in response to exercise in humans with and without metabolic syndrome. (2015) (160)
- Leptin applications in 2015: what have we learned about leptin and obesity? (2015) (160)
- Leptin at the intersection of neuroendocrinology and metabolism: current evidence and therapeutic perspectives. (2013) (158)
- Leptin in nonalcoholic fatty liver disease: a narrative review. (2015) (157)
- GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-controlled trial (2016) (157)
- Metformin and sulfonylureas in relation to cancer risk in type II diabetes patients: a meta-analysis using primary data of published studies. (2013) (157)
- Effect of dieting on plasma leptin, soluble leptin receptor, adiponectin and resistin levels in healthy volunteers (2004) (156)
- Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial (2011) (154)
- Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice. (2007) (153)
- Irisin in metabolic diseases (2018) (152)
- Covid-19 and Disparities in Nutrition and Obesity. (2020) (151)
- Ghrelin levels are not regulated by recombinant leptin administration and/or three days of fasting in healthy subjects. (2004) (150)
- Recombinant methionyl human leptin therapy in replacement doses improves insulin resistance and metabolic profile in patients with lipoatrophy and metabolic syndrome induced by the highly active antiretroviral therapy. (2006) (150)
- Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk. (2008) (147)
- Regular consumption of nuts is associated with a lower risk of cardiovascular disease in women with type 2 diabetes. (2009) (146)
- Long-term metreleptin treatment increases bone mineral density and content at the lumbar spine of lean hypoleptinemic women. (2011) (145)
- Risk factors for prostate cancer: a case‐control study in Greece (1999) (143)
- Commentary: COVID-19 in patients with diabetes (2020) (141)
- Androgens in preeclampsia. (1999) (140)
- Effect of birth weight and maternal smoking on cord blood leptin concentrations of full-term and preterm newborns. (1997) (139)
- Predictive value of serum and follicular fluid leptin concentrations during assisted reproductive cycles in normal women and in women with the polycystic ovarian syndrome. (2000) (136)
- Pharmacotherapy of obesity: Available medications and drugs under investigation. (2019) (135)
- Low adiponectin levels are associated with renal cell carcinoma: A case‐control study (2007) (135)
- Circulating irisin in healthy, young individuals: day-night rhythm, effects of food intake and exercise, and associations with gender, physical activity, diet, and body composition. (2014) (135)
- The role of the fat mass and obesity associated gene (FTO) in breast cancer risk (2011) (135)
- Leptin in relation to carcinoma In situ of the breast: A study of pre‐menopausal cases and controls (1999) (132)
- Adipose tissue, obesity and non-alcoholic fatty liver disease. (2017) (130)
- Adiponectin Genetic Variability, Plasma Adiponectin, and Cardiovascular Risk in Patients With Type 2 Diabetes (2006) (127)
- Genetic Variability in the TNF-α Promoter Is Not Associated with Type II Diabetes Mellitus (NIDDM) (1995) (127)
- Irisin: a renaissance in metabolism? (2013) (127)
- Efficacy of Metreleptin in Obese Patients With Type 2 Diabetes: Cellular and Molecular Pathways Underlying Leptin Tolerance (2011) (127)
- Pharmacotherapy of type 2 diabetes: An update. (2018) (126)
- Dietary fat and carbohydrates are independently associated with circulating insulin-like growth factor 1 and insulin-like growth factor-binding protein 3 concentrations in healthy adults. (1999) (125)
- Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes. (2015) (122)
- Obesity as a risk factor for Alzheimer's disease: weighing the evidence (2018) (121)
- Coffee Consumption Is Associated With Higher Plasma Adiponectin Concentrations in Women With or Without Type 2 Diabetes (2008) (120)
- Effects of a 1‐year exercise and lifestyle intervention on irisin, adipokines, and inflammatory markers in obese children (2014) (120)
- Effects of leptin and adiponectin on pancreatic β-cell function. (2011) (119)
- Peptide YY Levels Are Elevated After Gastric Bypass Surgery (2006) (118)
- Circulating insulin concentrations, smoking, and alcohol intake are important independent predictors of leptin in young healthy men. (1998) (118)
- Metabolic health and weight: Understanding metabolically unhealthy normal weight or metabolically healthy obese patients. (2016) (118)
- Pancreatic cancer expresses adiponectin receptors and is associated with hypoleptinemia and hyperadiponectinemia: a case–control study (2009) (118)
- Role of Leptin in Reproduction (2000) (117)
- Leptin and the brain: influences on brain development, cognitive functioning and psychiatric disorders. (2015) (117)
- Selected dietary flavonoids are associated with markers of inflammation and endothelial dysfunction in U.S. women. (2011) (114)
- Association of Adipokines with Development and Progression of Nonalcoholic Fatty Liver Disease (2018) (114)
- Adiponectin, lipids and atherosclerosis (2017) (113)
- Adherence to healthy eating patterns is associated with higher circulating total and high-molecular-weight adiponectin and lower resistin concentrations in women from the Nurses' Health Study. (2008) (112)
- Variants of the adiponectin and adiponectin receptor 1 genes and breast cancer risk. (2008) (112)
- Hypovitaminosis D in bariatric surgery: A systematic review of observational studies. (2016) (111)
- Leptin as a Therapeutic Agent—Trials and Tribulations (2000) (110)
- Age, sex, and smoking are predictors of circulating insulin-like growth factor 1 and insulin-like growth factor-binding protein 3. (1999) (110)
- Central nervous system regulation of eating: Insights from human brain imaging. (2016) (110)
- Adiponectin: a link between obesity and cancer (2006) (109)
- Human Immunodeficiency Virus/Highly Active Antiretroviral Therapy-Associated Metabolic Syndrome: Clinical Presentation, Pathophysiology, and Therapeutic Strategies (2003) (108)
- Human immunodeficiency virus type 1-related lipoatrophy and lipohypertrophy are associated with serum concentrations of leptin. (2003) (106)
- Gender differences in leptin levels during puberty are related to the subcutaneous fat depot and sex steroids. (1998) (105)
- Insulin resistance and vascular dysfunction in nondiabetic Asian Indians. (2004) (103)
- Association of the +45T>G and +276G>T polymorphisms in the adiponectin gene with insulin resistance in nondiabetic Greek women. (2009) (102)
- Physical Activity and Risk of Endometrial Cancer: A Population-Based Prospective Cohort Study (2006) (102)
- Type 2 diabetes mellitus and medications for type 2 diabetes mellitus are associated with risk for and mortality from cancer in a German primary care cohort. (2011) (101)
- Leptin in relation to resumption of menses in women with anorexia nervosa (1998) (100)
- Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty Liver Disease. (2021) (99)
- Short-term hyperthyroidism has no effect on leptin levels in man. (1997) (99)
- Effects of Lipid-Lowering Drugs on Irisin in Human Subjects In Vivo and in Human Skeletal Muscle Cells Ex Vivo (2013) (98)
- Gene expression of PPARgamma and PGC-1alpha in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training. (2010) (98)
- Leptin and the Hypothalamic-Pituitary Regulation of the Gonadotropin-Gonadal Axis (2004) (97)
- Serum Steroid Hormone Levels, Sex Hormone‐Binding Globulin, and Body Mass Index in the Etiology of Postmenopausal Breast Cancer (1996) (96)
- Low circulating adiponectin and resistin, but not leptin, levels are associated with multiple myeloma risk: a case–control study (2009) (95)
- Reproducibility of Plasma, Red Blood Cell, and Urine Biomarkers among Premenopausal and Postmenopausal Women from the Nurses' Health Studies (2010) (95)
- Total and High–Molecular Weight Adiponectin in Relation to Metabolic Variables at Baseline and in Response to an Exercise Treatment Program (2007) (93)
- Insulin resistance: the clinical spectrum. (1995) (93)
- Associations of Total and High-Molecular-Weight Adiponectin With All-Cause and Cardiovascular Mortality in Older Persons: The Cardiovascular Health Study (2012) (91)
- Walnut Consumption Increases Satiation but Has No Effect on Insulin Resistance or the Metabolic Profile Over a 4‐day Period (2010) (91)
- Circulating resistin in lean, obese, and insulin-resistant mouse models: lack of association with insulinemia and glycemia. (2005) (91)
- A prospective study of maternal prenatal weight and offspring cardiometabolic health in midchildhood. (2014) (90)
- Irisin in response to acute and chronic whole-body vibration exercise in humans. (2014) (90)
- Leptin in autoimmune diseases. (2015) (90)
- Syndromes of Severe Insulin Resistance (1998) (89)
- Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice (2012) (88)
- Contribution of dihydrotestosterone to male sexual behaviour (1995) (85)
- The emerging role of endocrine disruptors in pathogenesis of insulin resistance: a concept implicating nonalcoholic fatty liver disease. (2012) (85)
- Circulating irisin, omentin-1, and lipoprotein subparticles in adults at higher cardiovascular risk. (2014) (85)
- Adiponectin as a target for the treatment of nonalcoholic steatohepatitis with thiazolidinediones: A systematic review. (2016) (85)
- Resistin is associated with biomarkers of inflammation while total and high-molecular weight adiponectin are associated with biomarkers of inflammation, insulin resistance, and endothelial function. (2010) (84)
- Adiponectin in relation to childhood myeloblastic leukaemia (2006) (84)
- Phase II Study of Androgen Synthesis Inhibition with Ketoconazole, Hydrocortisone, and Dutasteride in Asymptomatic Castration-Resistant Prostate Cancer (2009) (82)
- Adiponectin receptor expression is elevated in colorectal carcinomas but not in gastrointestinal stromal tumors. (2008) (82)
- Responsiveness to peripherally administered melanocortins in lean and obese mice. (2004) (82)
- Association Between Primary Hypothyroidism and Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. (2018) (81)
- Cord blood leptin concentrations in relation to intrauterine growth (1999) (81)
- Irisin in humans: recent advances and questions for future research. (2014) (80)
- Effect of an intensive lifestyle intervention on atrial fibrillation risk in individuals with type 2 diabetes: the Look AHEAD randomized trial. (2015) (80)
- Circulating Adiponectin Levels and Expression of Adiponectin Receptors in Relation to Lung Cancer: Two Case-Control Studies (2008) (80)
- A prospective study of soluble tumor necrosis factor-alpha receptor II (sTNF-RII) and risk of coronary heart disease among women with type 2 diabetes. (2005) (80)
- Genome-wide association study identifies polymorphisms in LEPR as determinants of plasma soluble leptin receptor levels. (2010) (80)
- Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE(-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis (2021) (79)
- Severe Leptin Resistance in Brown Fat-Deficient Uncoupling Protein Promoter-Driven Diphtheria Toxin A Mice Despite Suppression of Hypothalamic Neuropeptide Y and Circulating Corticosterone Concentrations (1998) (79)
- The Effect of the Mediterranean Diet on Metabolic Health: A Systematic Review and Meta-Analysis of Controlled Trials in Adults (2020) (79)
- 20 years of leptin: role of leptin in human reproductive disorders. (2014) (79)
- Leptin and Amylin Act in an Additive Manner to Activate Overlapping Signaling Pathways in Peripheral Tissues (2010) (79)
- Relationship of leptin to bone mineralization in children and adolescents. (2003) (78)
- Diet quality is associated with circulating C-reactive protein but not irisin levels in humans. (2014) (78)
- Circulating Insulin and C-Peptide Levels and Risk of Breast Cancer among Predominately Premenopausal Women (2007) (76)
- A dietary pattern characterized by high consumption of whole-grain cereals and low-fat dairy products and low consumption of refined cereals is positively associated with plasma adiponectin levels in healthy women. (2008) (75)
- The role of leptin in regulating neuroendocrine function in humans. (2004) (74)
- Walnut-enriched diet reduces fasting non-HDL-cholesterol and apolipoprotein B in healthy Caucasian subjects: a randomized controlled cross-over clinical trial. (2014) (73)
- Leptin and Soluble Leptin Receptor Levels in Plasma and Risk of Type 2 Diabetes in U.S. Women (2009) (72)
- Posttraumatic stress disorder, alone or additively with early life adversity, is associated with obesity and cardiometabolic risk. (2015) (72)
- Omics, big data and machine learning as tools to propel understanding of biological mechanisms and to discover novel diagnostics and therapeutics. (2018) (71)
- Non-invasive diagnosis of non-alcoholic steatohepatitis and fibrosis with the use of omics and supervised learning: a proof of concept study. (2019) (71)
- Decreased serum leptin in bulimia nervosa. (2000) (71)
- Stem cells in the treatment of diabetes mellitus - Focus on mesenchymal stem cells. (2019) (71)
- Neonatal leptin levels are strongly associated with female gender, birth length, IGF‐I levels and formula feeding (2005) (71)
- Leptin and Hormones: Energy Homeostasis. (2016) (71)
- Regulation of cell proliferation and malignant potential by irisin in endometrial, colon, thyroid and esophageal cancer cell lines. (2014) (71)
- The Development of INT131 as a Selective PPARγ Modulator: Approach to a Safer Insulin Sensitizer (2008) (70)
- Adherence to the Mediterranean diet during pregnancy and offspring adiposity and cardiometabolic traits in childhood (2017) (70)
- Leptin: A hormone linking activation of neuroendocrine axes with neuropathology (2015) (70)
- Serum adiponectin levels and tissue expression of adiponectin receptors are associated with risk, stage, and grade of colorectal cancer. (2011) (70)
- Peptide YY levels are decreased by fasting and elevated following caloric intake but are not regulated by leptin (2005) (69)
- Direct Role of Adiponectin and Adiponectin Receptors in Endometrial Cancer: In Vitro and Ex Vivo Studies in Humans (2011) (69)
- GLP-1 promotes angiogenesis in human endothelial cells in a dose-dependent manner, through the Akt, Src and PKC pathways. (2013) (69)
- High Circulating Leptin Receptors with Normal Leptin Sensitivity in Liver-specific Insulin Receptor Knock-out (LIRKO) Mice* (2007) (69)
- Low testosterone levels predict all-cause mortality and cardiovascular events in women: a prospective cohort study in German primary care patients. (2010) (69)
- Commentary: COVID-19 and diabetes mellitus: What we know, how our patients should be treated now, and what should happen next (2020) (68)
- Implication of circulating irisin levels with brown adipose tissue and sarcopenia in humans. (2014) (68)
- Current and emerging pharmacological options for the treatment of nonalcoholic steatohepatitis. (2020) (68)
- Editorial: leptin as a therapeutic agent--trials and tribulations. (2000) (67)
- Adiponectin signals in prostate cancer cells through Akt to activate the mammalian target of rapamycin pathway. (2007) (66)
- Leptin as a Modulator of Neuroendocrine Function in Humans (2012) (66)
- Impact of a mixed strength and endurance exercise intervention on levels of adiponectin, high molecular weight adiponectin and leptin in breast cancer survivors (2009) (66)
- Advances in adipokines. (2012) (65)
- Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study. (2016) (65)
- Obesity and thyroid cancer: epidemiologic associations and underlying mechanisms (2013) (65)
- Differential associations of leptin with adiposity across early childhood (2013) (65)
- Insulin‐like growth factor 1 in hepatocellular carcinoma and metastatic liver cancer in men (2000) (65)
- A phase II study of mifepristone (RU‐486) in castration‐resistant prostate cancer, with a correlative assessment of androgen‐related hormones (2008) (65)
- Circulating melanin-concentrating hormone, agouti-related protein, and alpha-melanocyte-stimulating hormone levels in relation to body composition: alterations in response to food deprivation and recombinant human leptin administration. (2005) (64)
- Dietary walnut suppression of colorectal cancer in mice: Mediation by miRNA patterns and fatty acid incorporation. (2015) (64)
- Circulating adiponectin is inversely associated with risk of thyroid cancer: in vivo and in vitro studies. (2011) (64)
- Recombinant methionyl human leptin administration to achieve high physiologic or pharmacologic leptin levels does not alter circulating inflammatory marker levels in humans with leptin sufficiency or excess. (2005) (63)
- Polymorphisms of ADIPOQ and ADIPOR1 and prostate cancer risk. (2011) (63)
- Adipose tissue and reproductive health. (2017) (63)
- Leptin and adipocytokines: bridging the gap between immunity and atherosclerosis. (2007) (63)
- Day/night variations of high-molecular-weight adiponectin and lipocalin-2 in healthy men studied under fed and fasted conditions (2010) (62)
- Cardiovascular abnormalities in transgenic mice with reduced brown fat: an animal model of human obesity. (1999) (62)
- Caffeinated coffee does not acutely affect energy intake, appetite, or inflammation but prevents serum cortisol concentrations from falling in healthy men. (2011) (62)
- 20 years of leptin: from the discovery of the leptin gene to leptin in our therapeutic armamentarium. (2015) (61)
- Clinical review 159: Human immunodeficiency virus/highly active antiretroviral therapy-associated metabolic syndrome: clinical presentation, pathophysiology, and therapeutic strategies. (2003) (61)
- Short‐term fasting‐induced autonomic activation and changes in catecholamine levels are not mediated by changes in leptin levels in healthy humans (2006) (61)
- Fatty liver in lipodystrophy: A review with a focus on therapeutic perspectives of adiponectin and/or leptin replacement. (2019) (61)
- Predictors of sex hormone levels among the elderly: a study in Greece. (1998) (61)
- Commentary: Could iron chelators prove to be useful as an adjunct to COVID-19 Treatment Regimens? (2020) (60)
- Effects of trans fatty acids on glucose homeostasis: a meta-analysis of randomized, placebo-controlled clinical trials. (2012) (60)
- Minimal effect of a low-fat/high soy diet for asymptomatic, hormonally naive prostate cancer patients. (2003) (60)
- Insulin‐like growth factor‐I and binding protein‐3 in relation to childhood leukaemia (1999) (60)
- Effects of ezetimibe and/or simvastatin on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase gene expression: a randomized trial in healthy men. (2008) (60)
- Leptin does not mediate short-term fasting-induced changes in growth hormone pulsatility but increases IGF-I in leptin deficiency states. (2008) (60)
- IGF axis gene expression patterns are prognostic of survival in epithelial ovarian cancer. (2007) (60)
- Recombinant human growth hormone: old and novel uses. (1998) (60)
- Can a Selective PPARγ Modulator Improve Glycemic Control in Patients With Type 2 Diabetes With Fewer Side Effects Compared With Pioglitazone? (2014) (59)
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- Genetic variability in the TNF-alpha promoter is not associated with type II diabetes mellitus (NIDDM). (1995) (50)
- Total and High-Molecular-Weight Adiponectin and Risk of Incident Diabetes in Older People (2012) (49)
- Association of Maternal Short Sleep Duration With Adiposity and Cardiometabolic Status at 3 Years Postpartum (2011) (49)
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- Leptin and Adiponectin in the HIV Associated Metabolic Syndrome: Physiologic and Therapeutic Implications. (2006) (49)
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- Irisin: A true, circulating hormone. (2015) (49)
- Leptin Deficiency (2009) (49)
- Coffee drinking and risk of endometrial cancer—A population‐based cohort study (2009) (49)
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- Leptin administration to overweight and obese subjects for 6 months increases free leptin concentrations but does not alter circulating hormones of the thyroid and IGF axes during weight loss induced by a mild hypocaloric diet. (2011) (48)
- Lorcaserin Administration Decreases Activation of Brain Centers in Response to Food Cues and These Emotion- and Salience-Related Changes Correlate With Weight Loss Effects: A 4-Week-Long Randomized, Placebo-Controlled, Double-Blind Clinical Trial (2016) (48)
- Soluble leptin receptor and leptin are associated with baseline adiposity and metabolic risk factors, and predict adiposity, metabolic syndrome, and glucose levels at 2-year follow-up: the Cyprus Metabolism Prospective Cohort Study. (2011) (48)
- Leptin replacement improves postprandial glycemia and insulin sensitivity in human immunodeficiency virus-infected lipoatrophic men treated with pioglitazone: a pilot study. (2011) (48)
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- Commentary: Phosphodiesterase 4 inhibitors as potential adjunct treatment targeting the cytokine storm in COVID-19 (2020) (47)
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- Detailed assessments of childhood adversity enhance prediction of central obesity independent of gender, race, adult psychosocial risk and health behaviors. (2014) (47)
- Non-alcoholic fatty liver disease treatment in patients with type 2 diabetes mellitus; new kids on the block. (2020) (47)
- Serum adiponectin and leptin in relation to risk for preeclampsia: results from a large case-control study. (2011) (47)
- Leptin in congenital and HIV-associated lipodystrophy. (2015) (47)
- Circulating irisin levels are lower in patients with either stable coronary artery disease (CAD) or myocardial infarction (MI) versus healthy controls, whereas follistatin and activin A levels are higher and can discriminate MI from CAD with similar to CK-MB accuracy. (2017) (47)
- Relationship between serum adiponectin and prostate cancer grade (2008) (46)
- Gender differences in leptin levels during puberty are related to the subcutaneous fat depot and sex steroids. (1998) (46)
- Exercise and vitamin E intake are independently associated with metabolic abnormalities in human immunodeficiency virus-positive subjects: a cross-sectional study. (2003) (46)
- Guidelines on vitamin D replacement in bariatric surgery: Identification and systematic appraisal. (2016) (46)
- Adiponectin and resistin are associated with risk for myelodysplastic syndrome, independently from the insulin-like growth factor-I (IGF-I) system. (2008) (45)
- Serum leptin levels are higher but are not independently associated with severity or mortality in the multiple organ dysfunction/systemic inflammatory response syndrome: a matched case control and a longitudinal study (2001) (45)
- The-2548G/A polymorphism in the human leptin gene promoter region is associated with plasma free leptin levels; interaction with adiposity and gender in healthy subjects. (2003) (45)
- The emerging role of leptin in humans. (2006) (45)
- Diet quality and diet patterns in relation to circulating cardiometabolic biomarkers. (2016) (45)
- Adipokines in the HIV/HAART-associated lipodystrophy syndrome. (2013) (44)
- Short‐term treatment with ezetimibe, simvastatin or their combination does not alter circulating adiponectin, resistin or leptin levels in healthy men (2008) (44)
- The effect of underweight on female and male reproduction. (2020) (44)
- Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice. (2019) (44)
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- Circulating Adiponectin and Leptin in Relation to Myelodysplastic Syndrome: A Case-Control Study (2008) (43)
- Energy deprivation alters in a leptin- and cortisol-independent manner circulating levels of activin A and follistatin but not myostatin in healthy males. (2011) (43)
- Levels of circulating selenoprotein P, fibroblast growth factor (FGF) 21 and FGF23 in relation to the metabolic syndrome in young children (2014) (43)
- Alpha linolenic acid and oleic acid additively down-regulate malignant potential and positively cross-regulate AMPK/S6 axis in OE19 and OE33 esophageal cancer cells. (2014) (42)
- Genetic variability at the leptin receptor (LEPR) locus is a determinant of plasma fibrinogen and C-reactive protein levels. (2007) (42)
- Leptin in health and disease: facts and expectations at its twentieth anniversary. (2015) (42)
- Circulating lipocalin 2 is associated with body fat distribution at baseline but is not an independent predictor of insulin resistance: the prospective Cyprus Metabolism Study. (2011) (41)
- Selective capacity of metreleptin administration to reconstitute CD4+ T-cell number in females with acquired hypoleptinemia (2013) (41)
- Pharmacokinetics of Subcutaneous Recombinant Methionyl Human Leptin Administration in Healthy Subjects in the Fed and Fasting States (2008) (41)
- Leptin in relation to growth and developmental processes in the fetus. (2002) (40)
- Lifestyle modification increases circulating adiponectin concentrations but does not change vaspin concentrations. (2011) (39)
- Absence of relationship between steroid hormone levels and prostate cancer tumor grade. (2009) (39)
- Selective PPARγ modulator INT131 normalizes insulin signaling defects and improves bone mass in diet-induced obese mice. (2012) (39)
- The effect of excess body fat on female and male reproduction. (2020) (39)
- Higher fetuin-A, lower adiponectin and free leptin levels mediate effects of excess body weight on insulin resistance and risk for myelodysplastic syndrome. (2013) (38)
- Adherence to Mediterranean diet is favorably associated with metabolic parameters in HIV-positive patients with the highly active antiretroviral therapy-induced metabolic syndrome and lipodystrophy. (2009) (38)
- Serum adiponectin as a predictor of childhood non-Hodgkin's lymphoma: a nationwide case-control study. (2009) (38)
- Hormonal, Lifestyle, and Dietary Factors in Relation to Leptin among Elderly Men (1999) (38)
- Leptin therapy alters appetite and neural responses to food stimuli in brain areas of leptin-sensitive subjects without altering brain structure. (2014) (38)
- Body fat redistribution and metabolic abnormalities in HIV-infected patients on highly active antiretroviral therapy: novel insights into pathophysiology and emerging opportunities for treatment. (2011) (38)
- Relations of plasma total and high-molecular-weight adiponectin to new-onset heart failure in adults ≥65 years of age (from the Cardiovascular Health study). (2014) (37)
- Chemerin is expressed mainly in pancreas and liver, is regulated by energy deprivation, and lacks day/night variation in humans. (2013) (37)
- Leptin in relation to prostate cancer and benign prostatic hyperplasia. (1998) (37)
- Leptin and the hypothalamus: neuroendocrine regulation of food intake (1999) (37)
- Circulating resistin levels are not associated with fat redistribution, insulin resistance, or metabolic profile in patients with the highly active antiretroviral therapy-induced metabolic syndrome. (2005) (37)
- Can measurements of IGF-1 and IGFBP-3 improve the sensitivity of prostate-cancer screening? (2000) (37)
- Abdominal Obesity, Independent from Caloric Intake, Accounts for the Development of Intestinal Tumors in Apc1638N/+ Female Mice (2013) (36)
- Non-alcoholic fatty liver disease and steatohepatitis: State of the art on effective therapeutics based on the gold standard method for diagnosis (2020) (36)
- Gestational Glucose Tolerance and Maternal Metabolic Profile at 3 Years Postpartum (2011) (36)
- Leptin and Soluble Leptin Receptor in Follicular Fluid (2003) (35)
- Simultaneous and continuous 24-hour plasma and cerebrospinal fluid leptin measurements: dissociation of concentrations in central and peripheral compartments. (2004) (35)
- Prediagnosis Plasma Adiponectin in Relation to Colorectal Cancer Risk According to KRAS Mutation Status. (2016) (35)
- Leptin alters energy intake and fat mass but not energy expenditure in lean subjects (2020) (35)
- First and second trimester gestational weight gains are most strongly associated with cord blood levels of hormones at delivery important for glycemic control and somatic growth. (2017) (34)
- Early life adversity and/or posttraumatic stress disorder severity are associated with poor diet quality, including consumption of trans fatty acids, and fewer hours of resting or sleeping in a US middle-aged population: A cross-sectional and prospective study. (2015) (34)
- IGF1 and IGFBP3 in acute respiratory distress syndrome. (2012) (34)
- r-metHuLeptin improves highly active antiretroviral therapy-induced lipoatrophy and the metabolic syndrome, but not through altering circulating IGF and IGF-binding protein levels: observational and interventional studies in humans. (2008) (34)
- Circulating alanine transaminase (ALT) and γ-glutamyl transferase (GGT), but not fetuin-A, are associated with metabolic risk factors, at baseline and at two-year follow-up: the prospective Cyprus Metabolism Study. (2014) (34)
- Insulin resistance in relation to melanoma risk (2011) (34)
- Associations of cord blood metabolites with perinatal characteristics, newborn anthropometry, and cord blood hormones in project viva. (2017) (34)
- Effects of combined low‐dose spironolactone plus vitamin E vs vitamin E monotherapy on insulin resistance, non‐invasive indices of steatosis and fibrosis, and adipokine levels in non‐alcoholic fatty liver disease: a randomized controlled trial (2017) (34)
- B-cell chronic lymphocytic leukemia risk in association with serum leptin and adiponectin: a case–control study in Greece (2010) (33)
- Circulating Chemerin Is Associated With Carotid Plaque Instability, Whereas Resistin Is Related to Cerebrovascular Symptomatology (2016) (33)
- Clinical review 97: Syndromes of severe insulin resistance. (1998) (33)
- Cord blood irisin levels are positively correlated with birth weight in newborn infants. (2015) (33)
- Sodium-glucose co-transporter-2 inhibitors (SGLT2i) use and risk of amputation: an expert panel overview of the evidence. (2019) (33)
- Amylin and leptin activate overlapping signalling pathways in an additive manner in mouse GT1-7 hypothalamic, C2C12 muscle and AML12 liver cell lines (2011) (33)
- Circulating levels of gastrointestinal hormones in response to the most common types of bariatric surgery and predictive value for weight loss over one year: Evidence from two independent trials (2019) (33)
- Lorcaserin treatment decreases body weight and reduces cardiometabolic risk factors in obese adults: A six‐month, randomized, placebo‐controlled, double‐blind clinical trial (2019) (32)
- The role of leptin and hypothalamic neuropeptides in energy homeostasis: update on leptin in obesity. (2001) (32)
- Inflammation: A key player linking obesity with malignancies. (2018) (32)
- Estrogens, Testosterone and Sex Hormone Binding Globulin in Relation to Liver Cancer in Men (2001) (31)
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- Intensive Weight Loss Intervention and Cancer Risk in Adults with Type 2 Diabetes: Analysis of the Look AHEAD Randomized Clinical Trial (2020) (31)
- Maternal diet and cord blood leptin and adiponectin concentrations at birth. (2010) (30)
- Adiponectin Receptor Expression in Human Malignant Tissues (2010) (30)
- Gender and body mass index modify the effect of increasing amounts of caffeinated coffee on postprandial glucose and insulin concentrations; a randomized, controlled, clinical trial. (2013) (29)
- Pharmacokinetics of recombinant methionyl human leptin after subcutaneous administration: variation of concentration-dependent parameters according to assay. (2007) (29)
- Commentary: Nonalcoholic or metabolic dysfunction-associated fatty liver disease? The epidemic of the 21st century in search of the most appropriate name. (2020) (28)
- Circulating adiponectin levels in relation to melanoma: a case-control study. (2007) (28)
- Mechanisms underlying the cardiometabolic protective effect of walnut consumption in obese people: A cross‐over, randomized, double‐blind, controlled inpatient physiology study (2019) (27)
- Leptin and adiponectin: Their role in diabetes (2007) (27)
- Follistatins in glucose regulation in healthy and obese individuals (2018) (27)
- Coffee consumption and risk of localized, advanced and fatal prostate cancer: a population-based prospective study. (2013) (27)
- The effect of Irisin on antioxidant system in liver. (2014) (27)
- Juvenile Paget disease. (2017) (27)
- Leptin treatment reduces body fat but does not affect lean body mass or the myostatin-follistatin-activin axis in lean hypoleptinemic women. (2011) (27)
- Walnut consumption increases activation of the insula to highly desirable food cues: A randomized, double‐blind, placebo‐controlled, cross‐over fMRI study (2018) (27)
- Physiology of Activins/Follistatins: Associations With Metabolic and Anthropometric Variables and Response to Exercise (2018) (26)
- Activin A and follistatin in patients with nonalcoholic fatty liver disease. (2016) (26)
- Distinct Dopaminergic Personality Patterns in Patients with Prolactinomas: A Comparison with Nonfunctioning Pituitary Adenoma Patients and Age- and Gender-Matched Controls (2012) (26)
- Variants of the adiponectin gene and diabetic microvascular complications in patients with type 2 diabetes. (2013) (26)
- Adiponectin pathway polymorphisms and risk of breast cancer in African Americans and Hispanics in the Women’s Health Initiative (2013) (26)
- Dehydroepiandrosterone Sulfate and Testosterone Are Independently Associated with Body Fat Distribution in Premenopausal Women (1996) (26)
- Irisin physiology, oxidative stress, and thyroid dysfunction: What next? (2015) (26)
- Dietary factors associated with plasma high molecular weight and total adiponectin levels in apparently healthy women. (2008) (25)
- Longer‐term liraglutide administration at the highest dose approved for obesity increases reward‐related orbitofrontal cortex activation in response to food cues: Implications for plateauing weight loss in response to anti‐obesity therapies (2019) (25)
- Maternal levels of corticotropin-releasing hormone during pregnancy in relation to adiponectin and leptin in early childhood. (2009) (25)
- Increased leptin levels in preeclampsia: associations with BMI, estrogen and SHBG levels. (2004) (25)
- Intractable hypercalcaemia due to parathyroid hormone‐related peptide secretion by a carcinoid tumour (1997) (25)
- Breast-feeding, adipokines, and childhood obesity. (2007) (24)
- The Leu72Met polymorphism of the ghrelin gene is associated with a decreased risk for type 2 diabetes. (2009) (24)
- Regulation of the activins-follistatins-inhibins axis by energy status: Impact on reproductive function. (2018) (24)
- The effect of leptin replacement on parathyroid hormone, RANKL-osteoprotegerin axis, and Wnt inhibitors in young women with hypothalamic amenorrhea. (2014) (24)
- Lack of mature lymphocytes results in obese but metabolically healthy mice when fed a high-fat diet (2015) (24)
- New-onset diabetes and statins: throw the bath water out, but, please, keep the baby! (2015) (24)
- Methylsulfonylmethane (MSM), an organosulfur compound, is effective against obesity-induced metabolic disorders in mice. (2016) (24)
- Total and High–Molecular Weight Adiponectin in Relation to Metabolic Variables at Baseline and in Response to an Exercise Treatment Program: Comparative Evaluation of Three Assays (2007) (24)
- Sex-Specific Associations of Maternal Gestational Glycemia with Hormones in Umbilical Cord Blood at Delivery (2016) (24)
- Preadipocyte factor-1 levels are higher in women with hypothalamic amenorrhea and are associated with bone mineral content and bone mineral density through a mechanism independent of leptin. (2011) (24)
- Deep transfer learning and data augmentation improve glucose levels prediction in type 2 diabetes patients (2021) (24)
- Amylin-induced downregulation of hippocampal neurogenesis is attenuated by leptin in a STAT3/AMPK/ERK-dependent manner in mice (2013) (23)
- Maternal short sleep duration is associated with increased levels of inflammatory markers at 3 years postpartum. (2011) (23)
- Coffee Consumption Is Associated With Higher Plasma Adiponectin Concentrations in Women With or Without Type 2 Diabetes (2008) (23)
- Preparing for the NASH Epidemic: A Call to Action. (2021) (23)
- Commentary: COVID-19 and obesity pandemics converge into a syndemic requiring urgent and multidisciplinary action (2020) (23)
- Insulin Glargine and NPH Insulin Increase to a Similar Degree Epithelial Cell Proliferation and Aberrant Crypt Foci Formation in Colons of Diabetic Mice (2010) (23)
- Short-term resistance to diet-induced obesity in A/J mice is not associated with regulation of hypothalamic neuropeptides. (2004) (23)
- Mediterranean diet is inversely associated with steatosis and fibrosis and decreases ten-year diabetes and cardiovascular risk in NAFLD subjects: Results from the ATTICA prospective cohort study. (2020) (23)
- Whither recombinant human leptin treatment for HIV-associated lipoatrophy and the metabolic syndrome? (2009) (23)
- Adiponectin and metformin additively attenuate IL1β-induced malignant potential of colon cancer. (2013) (22)
- Obeticholic acid for the treatment of nonalcoholic steatohepatitis: expectations and concerns. (2020) (22)
- Variants of the adiponectin and adiponectin receptor-1 genes and posttransplantation diabetes mellitus in renal allograft recipients. (2012) (22)
- Making progress in nonalcoholic fatty liver disease (NAFLD) as we are transitioning from the era of NAFLD to dys-metabolism associated fatty liver disease (DAFLD) (2020) (22)
- Leptin in Relation to the Lipodystrophy-Associated Metabolic Syndrome (2012) (22)
- Antitumor and antimetastatic effects of walnut oil in esophageal adenocarcinoma cells. (2017) (22)
- Endogenous risk factors for childhood leukemia in relation to the IGF system (Greece) (2000) (22)
- Growth hormone-binding protein is directly and IGFBP-3 is inversely associated with risk of female breast cancer. (2007) (22)
- Leptin in Leanness and Obesity: JACC State-of-the-Art Review. (2021) (22)
- Preparing for the NASH epidemic: A call to action. (2021) (22)
- Self-reported eating speed in relation to non-alcoholic fatty liver disease in adults (2016) (22)
- Circulating ApoJ is closely associated with insulin resistance in human subjects. (2018) (22)
- Integrating blood cell mechanics, platelet adhesive dynamics and coagulation cascade for modelling thrombus formation in normal and diabetic blood (2021) (21)
- Targeted analysis of three hormonal systems identifies molecules associated with the presence and severity of NAFLD. (2020) (21)
- Chemerin levels as predictor of acute coronary events: a case-control study nested within the veterans affairs normative aging study. (2014) (21)
- Effects of sodium-glucose co-transporter-2 (SGLT2) inhibitors on non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: ex quo and quo vadimus? (2019) (21)
- Short-term treatment with high dose liraglutide improves lipid and lipoprotein profile and changes hormonal mediators of lipid metabolism in obese patients with no overt type 2 diabetes mellitus: a randomized, placebo-controlled, cross-over, double-blind clinical trial (2019) (21)
- Insulin-Like Growth Factor Binding Protein-3 Predicts Survival from Acute Childhood Leukemia (2001) (20)
- Erratum: Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice (Diabetes (2004) 53 (2787-2796) (2005) (20)
- Alcohol intake and endometrial cancer risk: a meta-analysis of prospective studies (2010) (20)
- Genetic variation within IL18 is associated with insulin levels, insulin resistance and postprandial measures☆ (2011) (20)
- Regulation of mouse hepatic genes in response to diet induced obesity, insulin resistance and fasting induced weight reduction (2005) (20)
- Leptin Does Not Directly Regulate the Pancreatic Hormones Amylin and Pancreatic Polypeptide (2008) (20)
- Leptin trajectories from birth to mid-childhood and cardio-metabolic health in early adolescence. (2019) (20)
- Attachment and the Metabolic Syndrome in Midlife: The Role of Interview-Based Discourse Patterns (2014) (19)
- Elevated leptin fragments in renal failure correlate with BMI and haematopoiesis and are normalized by haemodialysis (2004) (19)
- Could the endocrine disruptor bisphenol-A be implicated in the pathogenesis of oral and oropharyngeal cancer? Metabolic considerations and future directions. (2019) (19)
- SERUM ADIPONECTIN AND INSULIN-LIKE GROWTH FACTOR 1 IN PREDOMINANTLY FEMALE PATIENTS WITH THYROID CANCER: ASSOCIATION WITH THE HISTOLOGIC CHARACTERISTICS OF THE TUMOR. (2016) (19)
- Metabolic pathways link childhood adversity to elevated blood pressure in midlife adults. (2016) (19)
- Identification and Saturable Nature of Signaling Pathways Induced by Metreleptin in Humans: Comparative Evaluation of In Vivo, Ex Vivo, and In Vitro Administration (2014) (19)
- Diet patterns, adipokines, and metabolism: where are we and what is next? (2014) (19)
- Novel Molecules Regulating Energy Homeostasis: Physiology and Regulation by Macronutrient Intake and Weight Loss (2016) (19)
- Undiagnosed diabetes is prevalent in younger adults and associated with a higher risk cardiometabolic profile compared to diagnosed diabetes. (2015) (19)
- Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors: Shaping the future after the further cardiovascular outcomes research with PCSK9 inhibition in subjects with elevated risk (FOURIER) trial. (2017) (19)
- Circulating vaspin and visfatin are not affected by acute or chronic energy deficiency or leptin administration in humans. (2011) (18)
- Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: a Review of Shared Cardiometabolic Risk Factors (2022) (18)
- Adiponectin administration prevents weight gain and glycemic profile changes in diet-induced obese immune deficient Rag1-/- mice lacking mature lymphocytes. (2016) (17)
- The presence of NAFLD influences the transition of metabolically healthy to metabolically unhealthy obesity and the ten-year cardiovascular disease risk: a population-based cohort study. (2021) (17)
- Association between circulating irisin and homocysteine in patients with nonalcoholic fatty liver disease (2015) (17)
- Bone metabolism in anorexia nervosa and hypothalamic amenorrhea. (2017) (17)
- Circulating follistatin displays a day-night rhythm and is associated with muscle mass and circulating leptin levels in healthy, young humans. (2016) (17)
- Nonalcoholic fatty liver disease: Updates on associations with the metabolic syndrome and lipid profile and effects of treatment with PPAR-γ agonists. (2017) (16)
- Memory advancement by intranasal insulin in type 2 diabetes (MemAID) randomized controlled clinical trial: Design, methods and rationale. (2020) (16)
- Leptin in congenital or HIV-associated lipodystrophy and metabolic syndrome: a need for more mechanistic studies and large, randomized, placebo-controlled trials. (2012) (16)
- Severe insulin resistance syndromes. (2021) (16)
- Outcome of percutaneous transluminal coronary angioplasty in patients with subclinical hypothyroidism. (1995) (16)
- The Val81 missense mutation of the melanocortin 3 receptor gene, but not the 1908C/T nucleotide polymorphism in lamin A/C gene, is associated with hyperleptinemia and hyperinsulinemia in obese Greek Caucasians (2004) (15)
- Omega-3 supplementation and cardiovascular disease: formulation-based systematic review and meta-analysis with trial sequential analysis (2020) (15)
- Novel Non-invasive Approaches to the Treatment of Obesity: From Pharmacotherapy to Gene Therapy. (2021) (15)
- Leptin administered in physiological or pharmacological doses does not regulate circulating angiogenesis factors in humans (2011) (15)
- Incretin-based therapies in 2021 – Current status and perspectives for the future (2021) (15)
- Decreasing Lean Body Mass with Age: Challenges and Opportunities for Novel Therapies (2017) (15)
- Serum Levels of Activins, Follistatins, and Growth Factors in Neoplasms of the Breast: A Case-Control Study (2018) (15)
- Associations of maternal and cord blood adipokines with offspring adiposity in Project Viva: is there an interaction with child age? (2018) (15)
- trans-Fatty acids, insulin resistance/diabetes, and cardiovascular disease risk: should policy decisions be based on observational cohort studies, or should we be waiting for results from randomized placebo-controlled trials? (2011) (15)
- Placental proteases PAPP-A and PAPP-A2, the binding proteins they cleave (IGFBP-4 and -5), and IGF-I and IGF-II: levels in umbilical cord blood and associations with birth weight and length. (2019) (15)
- Effects of simvastatin and ezetimibe on interleukin-6 and high-sensitivity C-reactive protein (2013) (15)
- Exercising insulin sensitivity: AMPK turns on autophagy! (2015) (15)
- ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways (2019) (15)
- Obesity: seize the day, fight the fat. (2019) (15)
- Omentin-1 levels are reduced by pharmacologic doses of leptin, but remain unaffected by energy deprivation and display no day-night variation (2014) (14)
- Predictive value of gastrointestinal hormones on weight loss. (2019) (14)
- Peroxisome Proliferator Activator Receptor γ Coactivator-1 Expression Is Reduced in Obesity (2007) (14)
- Obesity and diabetes. (2006) (14)
- Optimizing bone health in anorexia nervosa and hypothalamic amenorrhea: new trials and tribulations. (2012) (14)
- Quantifying Fibrinogen-Dependent Aggregation of Red Blood Cells in Type 2 Diabetes Mellitus (2020) (14)
- Leptin and Soluble Leptin Receptor Levels in Plasma and Risk of Type 2 Diabetes in US Women : A Prospective Study Running title : leptin , soluble leptin receptor , and diabetes risk (2009) (14)
- Will medications that mimic gut hormones or target their receptors eventually replace bariatric surgery? (2019) (14)
- Fibroblast Growth Factor 21 Levels in Young Healthy Females Display Day and Night Variations and Are Increased in Response to Short-Term Energy Deprivation Through a Leptin-Independent Pathway (2013) (14)
- Non-alcoholic fatty liver disease and colorectal cancer: A marker of risk or common causation? (2018) (14)
- GnRH Deficient Patients With Congenital Hypogonadotropic Hypogonadism: Novel Genetic Findings in ANOS1, RNF216, WDR11, FGFR1, CHD7, and POLR3A Genes in a Case Series and Review of the Literature (2020) (13)
- Obesity, eating disorders and restrained eating: is leptin the missing link? (1997) (13)
- Differential Effects of Oral and Intravenous Lipid Administration on Key Molecules Related to Energy Homeostasis. (2016) (13)
- In prostate cancer, low adiponectin levels are not associated with insulin resistance (2015) (13)
- Serum steroids in relation to prostate cancer risk in a case-control study (Greece) (1997) (13)
- Obese individuals with more components of the metabolic syndrome and/or prediabetes demonstrate decreased activation of reward-related brain centers in response to food cues in both the fed and fasting states: A preliminary fMRI study (2016) (13)
- Short-term energy deprivation alters activin a and follistatin but not inhibin B levels of lean healthy women in a leptin-independent manner. (2011) (13)
- Lipodystrophy: Time for a global registry and randomized clinical trials to assess efficacy, safety and cost-effectiveness of established and novel medications. (2017) (13)
- Predictors of Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor–Binding Protein-3 in Critical Illness* (2015) (13)
- Helicobacter pylori infection and nonalcoholic fatty liver disease: Are the four meta-analyses favoring an intriguing association pointing to the right direction? (2019) (13)
- A prospective evaluation of clinical and genetic predictors of weight changes in breast cancer survivors (2017) (13)
- Associations of maternal prenatal smoking with umbilical cord blood hormones: the Project Viva cohort. (2017) (12)
- Clusterin (apolipoprotein J): wither link with diabetes and cardiometabolic risk? (2011) (12)
- W(h)ither metreleptin for lipodystrophy and the metabolic syndrome? (2010) (12)
- GEOFFREY HARRIS PRIZE LECTURE 2018: Novel pathways regulating neuroendocrine function, energy homeostasis and metabolism in humans. (2019) (12)
- Ciliary neurotrophic factor upregulates follistatin and Pak1, causes overexpression of muscle differentiation related genes and downregulation of established atrophy mediators in skeletal muscle. (2016) (12)
- Changes in Thyroid Hormone Levels Within the Normal and/or Subclinical Hyper- or Hypothyroid Range Do Not Affect Circulating Irisin Levels in Humans. (2016) (12)
- γ-Catenin is an independent prognostic marker in early stage colorectal cancer (2010) (12)
- Immune therapy in type 1 diabetes mellitus - Attempts to untie the Gordian knot? (2016) (11)
- Irisin: good or bad for the bone? A new path forward after the reported discovery of irisin receptor? (2019) (11)
- Linking Hepatic Transcriptional Changes to High–Fat Diet Induced Physiology for Diabetes-Prone and Obese-Resistant Mice (2007) (11)
- Elafibranor and liraglutide improve differentially liver health and metabolism in a mouse model of non‐alcoholic steatohepatitis (2021) (11)
- Cord Blood Adipocyte Fatty Acid–Binding Protein Levels Correlate With Gestational Age and Birth Weight in Neonates (2017) (11)
- Circulating Irisin Levels Are Not Affected by Coffee Intake: A Randomized Controlled Trial (2014) (11)
- The role of glicentin and oxyntomodulin in human metabolism: new evidence and new directions. (2020) (11)
- Physiological parameters regulating circulating levels of the IGFBP-4/Stanniocalcin-2/PAPP-A axis. (2017) (11)
- AMPK↔Sirt1: From a signaling network to a combination drug. (2016) (11)
- Statins in relation to adiponectin: A significant association with clinical implications. (2016) (10)
- Pharmacotherapy of type 2 diabetes: An update and future directions. (2022) (10)
- Relationship between a wide range of alcohol consumptions, components of the insulin-like growth factor system and adiponectin (2007) (10)
- Serum levels of insulin-like growth factor-1 and insulin-like growth factor-1 binding proteins after radical prostatectomy. (2002) (10)
- Whither Recombinant Human Growth Hormone? (1996) (10)
- Potential cardioprotective action of GLP-1: from bench to bedside. (2014) (10)
- Empagliflozin Improves Metabolic and Hepatic Outcomes in a Non-Diabetic Obese Biopsy-Proven Mouse Model of Advanced NASH (2021) (10)
- Preparing for the NASH Epidemic: A Call to Action (2021) (10)
- Epidemiology of obesity and diabetes: prevalence and trends. (2006) (10)
- From rest to stressed: endothelin-1 levels in young healthy smokers and non-smokers. (2015) (10)
- Endocrinologic and psychological effects of short-term dexamethasone in anorexia nervosa. (2000) (10)
- Intracellular leptin signaling following effective weight loss. (2015) (9)
- Leptin in renal failure. (1999) (9)
- Current child, but not maternal, snoring is bi-directionally related to adiposity and cardiometabolic risk markers: A cross-sectional and a prospective cohort analysis. (2017) (9)
- Association of Proinflammatory Molecules with Apoptotic Markers and Survival in Critically Ill Multiple Organ Dysfunction Patients (2003) (9)
- Editorial: Obesity, metabolic phenotypes and COVID-19 (2022) (9)
- A brief history of insulin resistance: from the first insulin radioimmunoassay to selectively targeting protein kinase C pathways. (2012) (9)
- The rise of biosimilars: How they got here and where they are going. (2017) (9)
- Circulating fetuin-A levels are not affected by short and long-term energy deprivation and/or by leptin administration. (2014) (9)
- Skeletal muscle mass and abdominal obesity are independent predictors of hepatic steatosis and interact to predict ten-year cardiovascular disease incidence: Data from the ATTICA cohort study. (2022) (9)
- ASGE EndoVators Summit: Defining the role and value of endoscopic therapies in obesity management. (2017) (9)
- Cord blood levels of osteopontin as a phenotype marker of gestational age and neonatal morbidities (2014) (9)
- The effect of dietary patterns on non-alcoholic fatty liver disease diagnosed by biopsy or magnetic resonance in adults: a systematic review of randomised controlled trials. (2022) (9)
- Circulating fetuin-A in patients with pancreatic cancer: a hospital-based case-control study (2014) (8)
- Advances in metabolism. (2013) (8)
- Leptin and Its Emerging Role in Children and Adolescents (2006) (8)
- Circulating clusterin (apolipoprotein J) levels do not have any day/night variability and are positively associated with total and LDL cholesterol levels in young healthy individuals. (2011) (8)
- Leptin administration in physiological or pharmacological doses does not alter circulating irisin levels in humans (2016) (8)
- Fetuin-A levels and free leptin index are reduced in patients with chronic lymphocytic leukemia: a hospital-based case-control study (2016) (7)
- Metreleptin therapy for nonalcoholic steatohepatitis: Open-label therapy interventions in two different clinical settings. (2021) (7)
- CYP1A2 polymorphisms modify the association of habitual coffee consumption with appetite, macronutrient intake, and body mass index: results from an observational cohort and a cross-over randomized study (2021) (7)
- New American Diabetes Association (ADA)/European Association for the Study of diabetes (EASD) guidelines for the pharmacotherapy of type 2 diabetes: placing them into a practicing physician's perspective. (2020) (7)
- Multiphysics and multiscale modeling of microthrombosis in COVID-19 (2022) (6)
- Fasting oxyntomodulin, glicentin, and gastric inhibitory polypeptide levels are associated with activation of reward‐ and attention‐related brain centres in response to visual food cues in adults with obesity: A cross‐sectional functional MRI study (2021) (6)
- COVID-19 editorial: mechanistic links and therapeutic challenges for metabolic diseases one year into the COVID-19 pandemic (2021) (6)
- Lack of Day/Night variation in fibroblast growth factor 21 levels in young healthy men (2014) (6)
- Reconstituted HDL-apoE3 promotes endothelial cell migration through ID1 and its downstream kinases ERK1/2, AKT and p38 MAPK. (2021) (6)
- Epitranscriptomic challenges and promises in metabolic diseases. (2022) (6)
- The Selective Peroxisome Proliferator‐Activated Receptor Gamma Modulator CHS‐131 Improves Liver Histopathology and Metabolism in a Mouse Model of Obesity and Nonalcoholic Steatohepatitis (2020) (6)
- Sleep apnea in relation to metabolism: An urgent need to study underlying mechanisms and to develop novel treatments for this unmet clinical need. (2017) (6)
- Circulating profile of Activin-Follistatin-Inhibin Axis in women with hypothalamic amenorrhea in response to leptin treatment. (2020) (6)
- Time to transition from a negative nomenclature describing what NAFLD is not, to a novel, pathophysiology-based, umbrella classification of fatty liver disease (FLD). (2022) (6)
- Treatment options to prevent diabetes in subjects with prediabetes: Efficacy, cost effectiveness and future outlook. (2017) (6)
- Hormones and hair patterning in men: a role for insulin-like growth factor 1? (1999) (6)
- Altered levels of adiponectin and adiponectin receptors may underlie the effect of ciliary neurotrophic factor (CNTF) to enhance insulin sensitivity in diet-induced obese mice. (2008) (6)
- Obese individuals with type 2 diabetes demonstrate decreased activation of the salience‐related insula and increased activation of the emotion/salience‐related amygdala to visual food cues compared to non‐obese individuals with diabetes: A preliminary study (2018) (6)
- Ciliary Neurotrophic FactorAx 15 Alters Energy Homeostasis , Decreases Body Weight , and Improves Metabolic Control in Diet-Induced Obese and UCP 1-DTA Mice (2004) (6)
- Accepting the torch. (2010) (5)
- Nutrition and metabolism : underlying mechanisms and clinical consequences (2009) (5)
- Novel concepts in lipoprotein particle metabolism and regulation. (2014) (5)
- Partnership and Extended Family Relationship Quality Moderate Associations Between Lifetime Psychiatric Diagnoses and Current Depressive Symptoms in Midlife (2014) (5)
- Adipokines and Metabolic Regulators in Human and Experimental Pulmonary Arterial Hypertension (2021) (5)
- Beyond glycemic control: New guidance on cardio-renal protection. (2019) (5)
- Quality of plant-based diets in relation to 10-year cardiovascular disease risk: the ATTICA cohort study (2022) (5)
- Fibroblast growth factor 21: A role in cardiometabolic disorders and cardiovascular risk prediction? (2019) (5)
- Metabolic regulation of activins in healthy individuals and in obese patients undergoing bariatric surgery (2020) (5)
- Effect of the glucagon‐like peptide‐1 analogue liraglutide versus placebo treatment on circulating proglucagon‐derived peptides that mediate improvements in body weight, insulin secretion and action: A randomized controlled trial (2020) (5)
- Leptin's role in regulation of neuroendocrine function (1999) (5)
- Diabetes type 1: Can it be treated as an autoimmune disorder? (2021) (5)
- Metreleptin for the treatment of lipodystrophy: leading the way among novel therapeutics for this unmet clinical need (2022) (5)
- Addressing the epidemic of fatty liver disease: A call to action, a call to collaboration, a call to moving the field forward. (2021) (5)
- Commentary: From mice to men: In search for dietary interventions to form the background on which pharmacotherapy for non-alcoholic fatty liver disease should be based. (2020) (5)
- Of mice and men: Why progress in the pharmacological management of obesity is slower than anticipated and what could be done about it? (2019) (5)
- Chapter 37 – Lipodystrophy Syndromes (2016) (5)
- Mediterranean Diet in Disease Prevention: Current Perspectives (2009) (4)
- Improvement in insulin sensitivity and prevention of high fat diet-induced liver pathology using a CXCR2 antagonist (2022) (4)
- Free Cortisol Is a More Accurate Marker for Adrenal Function and Does Not Correlate with Renal Function in Cirrhosis (2019) (4)
- Effect of valsartan on left ventricular anatomy and systolic function and aortic elasticity. (2009) (4)
- Severe obesity is associated with higher in-hospital mortality in a cohort of patientswith COVID-19 in the Bronx, New York (2020) (4)
- A novel MC4R deletion coexisting with FTO and MC1R gene variants, causes severe early onset obesity (2016) (4)
- Genome-wide association and Mendelian randomization study of fibroblast growth factor 21 reveals causal associations with hyperlipidemia and possibly NASH. (2022) (4)
- Diabetes mellitus: 100 years since the discovery of insulin. (2021) (4)
- Coffee consumption and risk of localized, advanced and fatal prostate cancer: a population-based prospective study. (2013) (4)
- Sulfated oxysterols as candidates for the treatment of nonalcoholic fatty liver disease. (2012) (4)
- Maternal Mid-pregnancy Leptin and Adiponectin Levels as Predictors of Autism Spectrum Disorder: A Prenatal Cohort Study. (2021) (4)
- Sex specific effect of ATPase inhibitory factor 1 on body weight: studies in high fat diet induced obese mice and genetic association studies in humans. (2020) (4)
- Lessons and Challenges from a 6-Month Randomized Pilot Study of Daily Ethanol Consumption (2017) (4)
- MemAID: Memory advancement with intranasal insulin vs. placebo in type 2 diabetes and control participants: a randomized clinical trial (2022) (4)
- Abnormal Peri-organ-Intra-organ Fat (APIFat) and Rheumatoid Arthritis: An Under-investigated Link for Increased Cardiovascular Risk? (2020) (4)
- Free IGF-1, Intact IGFBP-4, and PicoPAPP-A are Altered in Acute Myocardial Infarction Compared to Stable Coronary Artery Disease and Healthy Controls (2018) (4)
- Serum adipokine levels in patients with type 1 diabetes are associated with degree of obesity but only resistin is independently associated with atherosclerosis markers (2021) (4)
- IGF 1 and IGFBP 3 in acute respiratory distress syndrome (2011) (4)
- Dietary F at a nd C arbohydrates A re I ndependently A ssociated With C irculating I nsulin-Like G rowth F actor 1 a nd Insulin-Like G rowth F actor-Binding P rotein 3 Concentrations i n H ealthy A dults (1999) (4)
- Molecular modelling of novel ADCY3 variant predicts a molecular target for tackling obesity (2021) (3)
- ASGE EndoVators Summit: Defining the role and value of endoscopic therapies in obesity management. (2017) (3)
- Branched-Chain Amino Acids in relation to food preferences and insulin resistance in obese subjects consuming walnuts: A cross-over, randomized, double-blind, placebo-controlled inpatient physiology study. (2021) (3)
- Metabolism Updates: New directions, techniques, and exciting research that is broadening the horizons. (2019) (3)
- Old and new tools to study human brain physiology: Current state, future directions and implications for metabolic regulation (2019) (3)
- Vitamin D supplementation for obese adults undergoing bariatric surgery (2015) (3)
- Early growth and development of later life metabolic disorders. (2013) (3)
- Nutrients and Peripherally Secreted Molecules in Regulation of Energy Homeostasis (2006) (3)
- Drug-drug interactions in HIV medicine: a not so simple and straightforward road to the future. (2011) (3)
- Epidemiology and Prevention Associations of Total and High-Molecular-Weight Adiponectin With All-Cause and Cardiovascular Mortality in Older Persons (2012) (3)
- Statins' efficacy in non-alcoholic fatty liver disease: A systematic review and meta-analysis. (2022) (3)
- New research developments and insights from Metabolism. (2015) (3)
- factor in in (3)
- Quality of plant-based diets is associated with liver steatosis, which predicts type 2 diabetes incidence ten years later: Results from the ATTICA prospective epidemiological study. (2022) (3)
- Methods paper: Performance characteristics of novel assays for circulating levels of proglucagon-derived peptides and validation in a placebo controlled cross-over randomized clinical trial. (2022) (3)
- Recent guidelines for non-alcoholic fatty liver disease (NAFLD): Are they already outdated and in need of supplementation? (2022) (3)
- Resveratrol: is selectivity opening the key to therapeutic effects? (2012) (3)
- Slip sliding away: the need for continued discussion of the use of insulin sliding scale in hospitalized patients. (2015) (3)
- Cross-talk between SARS-CoV-2 infection and the insulin/IGF signaling pathway: Implications for metabolic diseases in COVID-19 and for post-acute sequelae of SARS-CoV-2 infection (2022) (3)
- Body fatness associations with cancer from recent epidemiologic studies. (2022) (3)
- Nutrition and Metabolism (2009) (3)
- Surgical Management of Obesity and Postoperative Care (2009) (3)
- The global burden of metabolic disease: Data from 2000 to 2019. (2023) (3)
- Research developments in metabolism 2018. (2019) (3)
- Making progress towards a better pathophysiological understanding and more promising therapeutic options for treating non-alcoholic steatohepatitis (NASH) / DASH (dysmetabolism associated steatohepatitis). (2020) (3)
- Advances at the intersection of sleep and metabolism research. (2018) (3)
- Irisin, a Novel Hormone and Exercise Intensity in Young Healthy Subjects (2013) (3)
- Association of circulating FGF-21 levels in the first week of life and postnatal growth in hospitalized preterm infants (2020) (2)
- Reproductive Endocrinology: Novel Insights into Pathophysiology and Clinical Management. (2018) (2)
- The Metabolic Syndrome (2009) (2)
- Circulating levels of five proglucagon-derived peptides in response to intravenous or oral glucose or lipids and to a mixed-meal in subjects with normal weight, overweight, and obesity. (2022) (2)
- Obesity — Genetics, Pathogenesis, Therapy (2010) (2)
- Circulating total and intact GDF-15 levels are not altered in response to weight loss induced by liraglutide or lorcaserin treatment in humans with obesity. (2022) (2)
- The emerging clinical significance of leptin in humans with absolute or relative leptin deficiency (2005) (2)
- Glucagon-Like Peptide-1 Receptor Agonists and Dual Glucose-Dependent Insulinotropic Polypeptide/Glucagon-Like Peptide-1 Receptor Agonists in the Treatment of Obesity/Metabolic Syndrome, Prediabetes/Diabetes and Non-Alcoholic Fatty Liver Disease—Current Evidence (2022) (2)
- Of mice and men: incretin actions in the central nervous system. (2019) (2)
- Non-alcoholic fatty liver disease in children. (2022) (2)
- Methods for Classifying, Diagnosing, and Monitoring Type II Diabetes (2009) (2)
- Novel Noninvasive Approaches to the Treatment of Obesity: From Pharmacotherapy to Gene Therapy. (2022) (2)
- Effects of statins on specialized pro-resolving mediators: An additional pathway leading to resolution of inflammation. (2022) (2)
- Serum follistatin is increased in thyroid cancer and is associated with adverse tumor characteristics in humans. (2021) (2)
- Daily transient coating of the intestine leads to weight loss and improved glucose tolerance. (2021) (2)
- Author response for "Mechanisms Underlying the Cardiometabolic Protective Effect of Walnut Consumption in Obese Subjects: A Cross‐Over, Randomized, Double‐Blinded, Controlled Inpatient Physiology Study" (2019) (2)
- Leptin therapy does not affect inflammatory markers. Author's reply (2005) (2)
- Sixty-six years of Metabolism, Clinical and Experimental: The journey of a journal and opportunities and challenges looking ahead. (2018) (2)
- Leptin, Immune Function, and Inflammation (2015) (2)
- Treating prediabetes in the obese: are GLP-1 analogues the answer? (2017) (2)
- Tools to study the human brain. (2019) (2)
- Variants in ADIPOQ gene are linked to adiponectin levels and lung function in young males independent of obesity (2020) (2)
- Genetics of Obesity and Diabetes (2006) (2)
- Preparing for the NASH epidemic: A call to action (2021) (2)
- Cord Leptin is Associated with Neuropsychomotor Development in Childhood (2019) (2)
- Outliers of bone metabolic diseases. (2017) (2)
- Leptin and Pubertal Development in Humans (2003) (2)
- Obesity, diabetes, and risk of cancer: a review of epidemiological studies. (2006) (2)
- Impact of physical activity on insulin levels in breast cancer survivors (2007) (2)
- Authors’ Response: Melanin-Concentrating Hormone and Energy Balance (2005) (2)
- Evaluation and refinement of the PRESTARt tool for identifying 12–14 year olds at high lifetime risk of developing type 2 diabetes compared to a clinicians assessment of risk: a cross-sectional study (2019) (2)
- The HAART-Induced Metabolic Syndrome (2006) (1)
- Diagnosing Obesity, Diabetes Mellitus, and Insulin Resistance Syndrome (2006) (1)
- Daily transient coating of the intestine leads to weight loss and improved glucose tolerance (2021) (1)
- The quest for the perfect biomarker of long-term glycemia: new studies, new trials and tribulations. (2011) (1)
- Gender Dimorphism and Lack of Day/Night Variation or Effects of Energy Deprivation on Undercarboxylated Osteocalcin Levels in Humans (2013) (1)
- Reflections on the continuum of insulin development one century after insulin's first use in humans: Following the trail of publications and patents viewed in the context of a collaborative process toward leveraging science to save lives. (2022) (1)
- Gender Disparities in the Treatment and Control of Cardiovascular Risk Factors in Type 2 Diabetes (2008) (1)
- Association of the C 45 T O G and C 276 G O T polymorphisms in the adiponectin gene with insulin resistance in nondiabetic Greek women (2009) (1)
- Atherosclerosis and peripheral vascular disease: sequelae of obesity and diabetes. (2006) (1)
- Testosterone levels in relation to cardiovascular risk factors and cardiovascular events in women; a cross-sectional and prospective cohort study in German primary care patients (2009) (1)
- Long-Term Impact of Weight Loss on Obesity and Obesity-Associated Comorbidities (2009) (1)
- Dietary calcium and body weight: what's the "skinny"? (2012) (1)
- culture: integrated response to TNF- adipokines by human adipocytes differentiated in Expression and secretion of inflammation-related (2011) (1)
- Erratum: Variants of the adiponectin and adiponectin receptor-1 genes and posttransplantation diabetes mellitus in renal allograft recipients (Journal of Clinical Endocrinology and Metabolism (2012) 97 (E129-E135) DOI: 10.1210/jc.2011-1796) (2013) (1)
- Major Nutrition Recommendations and Interventions for Subjects with Hyperlipidemia, Hypertension, and/or Diabetes (2009) (1)
- Isoform changes of action potential regulators in the ventricles of arrhythmogenic phospholamban-R14del humanized mouse hearts. (2022) (1)
- Authors’ Response: Leptin Therapy Does Not Affect Inflammatory Markers (2005) (1)
- Delta-like 1 (DLK1) is a possible mediator of vitamin D effects on bone and energy metabolism. (2020) (1)
- Leptin plays an anti-inflammatory role in acute pancreatitis (2003) (1)
- Diagnosis, Evaluation, and Medical Management of Obesity and Diabetes (2009) (1)
- Incretin therapy and beta cell function. (2015) (1)
- The Metabolism Award for Junior Investigators (2012) (1)
- Pharmacotherapy of obesity: an update on the available medications and drugs under investigation (2023) (1)
- Nutrition Recommendations and Interventions for Subjects with Cardiovascular Disease (2009) (1)
- GLP-1 PROMOTES ANGIOGENESIS IN A DOSE-DEPENDENT MANNER, THROUGH THE PI3K/AKT, PKC AND NITRIC OXIDE PATHWAYS (2012) (1)
- Levels of Atg5 determine pancreatic tumor formation and metastasis in mice (2018) (1)
- Leptin and Fetal Growth and Development (2003) (1)
- Long-term statin treatment for hepatic fibrosis in patients with nonalcoholic fatty liver disease: is it time to give the emperor a statin robe? (2021) (1)
- Melanin-concentrating hormone and energy balance. Author's reply (2005) (1)
- Insulin Resistance in States of Energy Excess: Underlying Pathophysiological Concepts (2009) (1)
- Secretion patterns of circulating osteoprotegerin and response to acute and chronic energy deprivation in young healthy adults. (2012) (1)
- Insulin Resistance, Obesity, Body Fat Distribution, and Risk of Cardiovascular Disease (2006) (1)
- Interventional changes of thyroid hormone levels do not affect circulating irisin levels in humans (2016) (1)
- Dose-related meta-analysis for Omega-3 fatty acids supplementation on major adverse cardiovascular events. (2022) (1)
- Infections in diabetes mellitus. (2006) (1)
- Body fat redistribution and metabolic abnormalities in HIV-infected patients on HAART: novel insights into pathophysiology and emerging opportunities for treatment (2011) (1)
- Environmental Inputs, Intake of Nutrients, and Endogenous Molecules Contributing to the Regulation of Energy Homeostasis (2009) (1)
- Non-alcoholic fatty liver disease in South and South-east Asians living in Western Countries: a major health problem calling for action (2017) (1)
- Role of leptin in human reproductive disorders (2014) (1)
- Response to High Fat Diet in Mice Activation, Role in Lymphocyte Survival, and Lymphocytes: Kinetics During Lymphocyte Leptin Receptor Expression and Signaling in (2006) (1)
- Abstract 453: Chemerin and Resistin Expression in Carotid Plaque Instability (2014) (0)
- PCSK9 and ANGPTL3 levels correlate with hyperlipidemia in HIV-lipoatrophy, are regulated by fasting and are not affected by leptin administered in physiologic or pharmacologic doses. (2022) (0)
- Abstract 10013: Total and High Molecular Weight Adiponectin and Future Risk of Ischemic Stroke and Coronary Heart Disease in Older Adults (2011) (0)
- Abstract 897: Leptin and Soluble Leptin Receptor Levels in Plasma and Risk of Type 2 Diabetes in US Women: A Prospective Study (2009) (0)
- Metabolism, clinical and experimental: seventy years young and growing. (2022) (0)
- Fibroblast Growth Factor-21 as a Potential Therapeutic Target of Nonalcoholic Fatty Liver Disease (2023) (0)
- Quantitative linkage of physiology and gene expression through empirical model construction: an investigation of diabetes (2003) (0)
- Contents Vol. 60, 2001 (2001) (0)
- Patient-specific deep offline artificial pancreas for blood glucose regulation in type 1 diabetes (2022) (0)
- Both Elafibranor and Liraglutide Improve NAFLD / NASH but Affect Differentially the Hepatic Lipidome and Metabolome in a Diet-Induced Obese and Biopsy-Confirmed Mouse Model of NASH (2021) (0)
- Regulation of the activin-follistatin hormonal system in relation to glucometabolic status in mice, in healthy humans and in obese individuals undergoing bariatric surgery (2021) (0)
- Responses of circulating irisin to different exercises in humans (2013) (0)
- Total Plasma Adiponectin Concentrations and Adipor1 and Adipor2 Gene Expression Are Associated With Features of Plaque Instability in Patients With Carotid Atherosclerosis (2013) (0)
- Research advances in metabolism 2015. (2016) (0)
- PO7-177 EFFECTS OF EZETIMIBE AND/OR SIMVASTATIN ON LDLR PROTEIN AND ON LDLR AND HMG-COA REDUCTASE GENE EXPRESSION: A RANDOMIZED TRIAL (2007) (0)
- Treatment of the Obese Patients With Type 2 Diabetes (2006) (0)
- CR Kahn High Circulating Leptin Receptors with Normal Leptin Sensitivity in Liver-Specific Insulin Receptor Knockout ( LIRKO ) Mice (2007) (0)
- Abstract 10859: Walnut-enriched Diet Reduces Fasting Non-HDL-cholesterol in Healthy Caucasian Subjects (2012) (0)
- Abstract 3484: Dietary Patterns And The Risk Of Mortality From All-causes, Cardiovascular Disease, And Cancer In Women (2007) (0)
- Nutrition and the Metabolic Syndrome: A Twenty-First-Century Epidemic of Obesity and Eating Disorders (2009) (0)
- Leptin, Adiponectin, Resistin, Ghrelin (2007) (0)
- Obesity: clinical manifestations and therapeutic: does the choice of diet make any difference? (2010) (0)
- OR01-5 Leptin Acts through Altering Energy Intake and Lipolysis to Reduce Body Weight but Has No Effect on Energy Expenditure, Physical Activity, and Sympathetic Nervous System in Humans (2019) (0)
- Research advances in metabolism 2016. (2017) (0)
- Adiponectin and the Cardiovascular System (2005) (0)
- A Novel Melanocortin-4-Receptor Gene Mutation Associated with Early Onset Severe Obesity (2015) (0)
- Subject Index Vol. 60, 2001 (2001) (0)
- 134 Physiological Regulators of Melanin-Concentrating Hormone (MCH) Receptor 1 Expression in Fat (2009) (0)
- Daily intranasal insulin at 40IU does not affect food intake and body composition: A placebo-controlled trial in older adults over a 24-week period with 24-weeks of follow-up. (2023) (0)
- Circulating levels of gastrointestinal hormones in prediabetes reversing to normoglycemia or progressing to diabetesin a year- a cross-sectional and prospective analysis. (2023) (0)
- Methods for Classifying, Diagnosing, and Monitoring Obesity (2009) (0)
- PCSK9 inhibition and cholesterol homeostasis in insulin producing β-cells (2022) (0)
- One year of changes for Metabolism, Clinical and Experimental: evolution and intelligent design at work (2011) (0)
- Association between serum adiponectin and prostate cancer risk (2008) (0)
- Geoffrey Harris Award (2018) (0)
- Association of BMI, adipokines and genetic variation with lung function (2017) (0)
- 159 Human Immunodeficiency Virus / Highly Active Antiretroviral Therapy-Associated Metabolic Syndrome : Clinical Presentation , Pathophysiology , and Therapeutic Strategies (2003) (0)
- Diet and Exercise in the Prevention and Management of the Metabolic Syndrome (2009) (0)
- Low muscle mass is linked with presence of non-alcoholic fatty liver disease irrespective to central obesity: highlights from a prospective epidemiological study in Greece (2022) (0)
- IGFBP3 Polymorphism Is Associated With Plasma Insulin-Like Growth Factor (IGF)-1 And Insulin-Like Growth Factor Binding Protein (IGFBP-3) In An Intensive Care Unit (ICU) Cohort (2011) (0)
- Simvastatin induces muscle damage, oxidative stress, and apoptosis in human skeletal muscle cells, and mito-TEMPO reverses simvastatin-induced cellular damage and irisin secretion. (2013) (0)
- Igf-i, igfbp-3 and psa in prostate cancer prediction (2001) (0)
- Dropout risk and effectiveness of retention strategies in the Memory Advancement by Intranasal Insulin in Type 2 Diabetes (MemAID) Clinical Trial. (2022) (0)
- MON-591 Effect of Liraglutide Treatment on Proglucagon-Derived Peptides (2020) (0)
- fat, reproductive, nutritional, and endocrine factors Plasma leptin in female athletes: relationship with body (2015) (0)
- Activins, follistatins and inhibins in postmenopausal osteoporosis: A proof of concept, case-control study. (2022) (0)
- Food Guide Pyramids and the 2005 MyPyramid (2009) (0)
- GLYCOSYLATED FIBRONECTIN AND INHIBIN ARE HIGHER AND ANTI-MÜLLERIAN HORMONE IS LOWER IN UMBILICAL CORD BLOOD WHEN MOTHERS HAVE PREECLAMPSIA. (2019) (0)
- Abstract 511: Total Circulating Adiponectin Levels and its Receptors are Associated with Histological and Immunohistochemical Features of Carotid Plaque Instability (2013) (0)
- Abstract 10390: Simvastatin Increases Irisin Concentrations in Human Subjects in Vivo and Irisin Expression and Secretion in Human Skeletal Muscle Cells ex Vivo (2013) (0)
- Central Integration of Peripheral Signals in Regulation of Energy Homeostasis (2006) (0)
- Liraglutide-induced effects on energy intake and glycemic profile are independent of total and intact GDF-15 levels in subjects with obesity and diabetes. (2022) (0)
- Contents Vol. 63, 2002 (2002) (0)
- ADIPOR1 (adiponectin receptor 1) (2011) (0)
- Abstract 124: Association of AdipoR2 mRNA Expression on Peripheral Monocytes With Carotid Plaque Instability (2014) (0)
- ncology bsence of Relationship etween Steroid Hormone Levels nd Prostate Cancer Tumor Grade avid (2009) (0)
- MATERNAL SECOND TRIMESTER CORTICOTROPIN-RELEASING HORMONE IN RELATION TO OFFSPRING ADIPONECTIN AND LEPTIN AT AGE 3 YEARS (2008) (0)
- Leptin lavolvement in C. difficlle toxin A (TxA) induced enteritis (2001) (0)
- Abstract 056: Associations of Total and High-Molecular-Weight Adiponectin with All-Cause and Cardiovascular Mortality in Older Persons: The Cardiovascular Health Study (CHS) (2012) (0)
- Abdominal Visceral Fat (AVF) is Related to Energy Expenditure, Leptin, and Fat Mass in Children and Adolescents † 473 (1998) (0)
- Abstract P012: Cardiac Biomarkers of Newborn Myocardial Injury, Cardiomyopathy and Inflammation are Associated with Indicators of Premature Cardiovascular Disease in Childhood: The National Institutes of Health Project VIVA Study (2012) (0)
- Obesity, diabetes, endothelial dysfunction. (2006) (0)
- Relationship between circulating adipokines and cholesterol efflux in subjects with severe carotid atherosclerosis. (2022) (0)
- Embryo quality may be associated with serum Inhibin B levels but not with serum or follicular fluid levels of other components of the Activin-Follistatin-Inhibin Axis. (2022) (0)
- Epidemiology and Prevention Associations of Total and High-Molecular-Weight Adiponectin With All-Cause and Cardiovascular Mortality in Older Persons The Cardiovascular Health Study (2012) (0)
- Cancer Therapy : Clinical Phase II Study of Androgen Synthesis Inhibition with Ketoconazole , Hydrocortisone , and Dutasteride in Asymptomatic Castration-Resistant Prostate Cancer (2009) (0)
- Title: IGF1 and IGFBP3 in the Acute Respiratory Distress Syndrome Running Title: IGF1 and IGFBP3 in ARDS (2011) (0)
- Contents, Vol. 54, 1997 (1995) (0)
- Leptin Therapy in Women with Hypothalamic Amenorrhea (2015) (0)
- PLENARY LECTURE - DSM – Novel and old adipokines in relation to obesity, metabolic syndrome, oxidative and ER stress (2013) (0)
- Future Developments in the Area of Pharmacotherapy (2006) (0)
- Liver steatosis, metabolically healthy obesity and ten-year cardiovascular disease risk: results from a population based cohort study (2021) (0)
- Hair Ionomic Profiles and Associations with Obesity Indicators from a Cypriot Young Adult Male Cohort (2013) (0)
- Future developments in the area of pharmacotherapy: molecules in early-stage preclinical development and in clinical trials that may affect energy homeostasis. (2006) (0)
- rats ileal hormone secretion and synthesis in Weight loss through ileal transposition is accompanied (2006) (0)
- Corrigendum to "Variants of the adiponectin gene and diabetic microvascular complications in patients with type 2 diabetes" [Metab. Clin. Exp. 62 (2013) 677-685]. (2017) (0)
- Medical Nutrition Therapy in the Treatment of Type 1 and Type 2 Diabetes (2009) (0)
- Abstract 598: Irisin, a Novel Hormone, and Its Response to Increasing Exercise Intensity in Young Healthy Subjects (2014) (0)
- Cohort Profile Cohort Profile : Project Viva (2015) (0)
- Subject Index Vol. 54,1997 (1997) (0)
- Associations among Childhood Sexual and Physical Abuse, Adult Mental Health, Social Functioning and Physical Health (2015) (0)
- 879-P: Dropout Risk and Effectiveness of Retention Strategies: A Substudy of the Memory Advancement by Intranasal Insulin (INI) in Type 2 Diabetes (MemAID) (2021) (0)
- Author response for "Effect of liraglutide vs. placebo treatment on circulating proglucagon‐derived peptides that mediate improvements in body weight, insulin secretion and action: a randomized controlled trial" (2020) (0)
- In memoriam: The life and times of Theodore B. Van Itallie (1919-2019). (2019) (0)
- Early metabolomic, lipid and lipoprotein changes in response to medical and surgical therapeutic approaches to obesity. (2022) (0)
- Research advances in metabolism 2017. (2018) (0)
- Genes and Gene–Environment Interactions in the Pathogenesis of Obesity and the Metabolic Syndrome (2009) (0)
- Central Integration of Environmental and Endogenous Signals Important in the Regulation of Food Intake and Energy Expenditure (2009) (0)
- P5328Meta-analysis for omega-3 supplementation and cardiovascular disease (2017) (0)
- Circulating lipoprotein(a) levels and health outcomes: Phenome-wide Mendelian randomization and disease-trajectory analyses. (2022) (0)
- Non-alcoholic fatty liver disease, Mediterranean diet and 10-year cardiovascular disease incidence: the mediating role of adiponectin. Highlights from the ATTICA prospective (2002–2012) study (2020) (0)
- In memoriam: The life and times of Theodore B. Van Itallie (1919-2019). (2020) (0)
- Abstract 1859: High Dose Atorvastatin Induces Myocardial Hypertrophy In Swine: Role Of Adiponectin And Akt (2007) (0)
- 718-P: Long-Term Safety of Intranasal Insulin (INI) in Insulin-Dependent Type 2 Diabetes (T2DM-IDDM): A Safety Substudy of Memory Advancement by Intranasal Insulin in Type 2 Diabetes (MemAID) Trial (2021) (0)
- Biosimilar and generic formulations of novel antidiabetic drugs: the role of liraglutide in clinical pharmacology of type 2 diabetes (2022) (0)
- 193-OR: Memory Advancement with Intranasal Insulin in Type 2 Diabetes: Randomized Control Trial (2021) (0)
- 719-P: Caloric Intake, Appetite, and Body Composition Outcomes of Long-Term Intranasal Insulin (INI) Administration: A Substudy of the Memory Advancement by INI in Type 2 Diabetes (MemAID) Study (2021) (0)
- INSULIN-LIKE GROWTH FACTOR 1 IN RELATION TO PROSTATE CANCER AND BENIGN PROSTATIC HYPERPLASIA. AUTHORS' REPLY (1998) (0)
- Subject Index Vol. 63, 2002 (2002) (0)
- Diabetes mellitus - clinical studies - 1 (2009) (0)
- Obesity and diabetes: the historical events marking the evolution of the understanding of the pathophysiology and treatment of two related diseases. (2006) (0)
- Circulating IGF-1 And IGFBP-3 Levels In The Acute Respiratory Distress Syndrome (2011) (0)
- 1503-PUB: Modeling the Prediction of Improvement on Gait and Cognition among Patients Receiving Intranasal Insulin (2022) (0)
- Author response for "Fasting oxyntomodulin, glicentin, and GIP levels are associated with activation of reward and attention‐related brain centers in response to visual food cues in adults with obesity: A cross‐sectional fMRI study" (2021) (0)
- 219-OR: Intranasal Insulin Enhanced Resting-State Functional Connectivity of Medio-Prefrontal Cortex in Type 2 Diabetes: A Substudy of the Memory Advancement with Type 2 Diabetes (MemAID) Randomized Control Trial (2022) (0)
- Correction: Nut consumption is associated with a shift of the NMR lipoprotein subfraction profile to a less atherogenic pattern among older individuals at high CVD risk (2022) (0)
- Corrigendum to "Genome-wide association and Mendelian randomization study of fibroblast growth factor 21 reveals causal associations with hyperlipidemia and possibly NASH" [Metab Volume 137, December 2022, 155329]. (2023) (0)
- ASSOCIATION OF TOTAL AND HIGH-MOLECULAR-WEIGHT ADIPONECTIN WITH NEW-ONSET HEART FAILURE IN OLDER ADULTS: THE CARDIOVASCULAR HEALTH STUDY (2012) (0)
- Recent Advances in Nutritional Sciences Energy Homeostasis , Obesity and Eating Disorders : Recent Advances in Endocrinology 1 (2004) (0)
- SERUM LEPTIN CONCENTRATIONS ARE RELATED TO BONE MASS IN YOUTH INDEPENDENTLY OF THE GH-IGF-I SYSTEM (2002) (0)
- Sodium-glucose cotransporter-2 inhibitors: A treatment option for recurrent vasovagal syndrome? (2022) (0)
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