Chuan He
#180,927
Most Influential Person Now
Chuan He's AcademicInfluence.com Rankings
Chuan Hechemistry Degrees
Chemistry
#5532
World Rank
#6728
Historical Rank
Organic Chemistry
#981
World Rank
#1108
Historical Rank
Chuan Hebiology Degrees
Biology
#15121
World Rank
#19036
Historical Rank
Genetics
#1754
World Rank
#1866
Historical Rank
Biochemistry
#2650
World Rank
#2830
Historical Rank
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Chemistry Biology
Chuan He's Degrees
- PhD Chemistry University of Chicago
- Bachelors Chemistry Peking University
Why Is Chuan He Influential?
(Suggest an Edit or Addition)Chuan He's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA (2011) (2365)
- Gene expression regulation mediated through reversible m6A RNA methylation (2014) (1206)
- Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. (2011) (1117)
- Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine (2011) (947)
- Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome (2012) (932)
- 5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging (2011) (750)
- Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming (2013) (494)
- Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA (2013) (374)
- Oxidative demethylation of 3‐methylthymine and 3‐methyluracil in single‐stranded DNA and RNA by mouse and human FTO (2008) (364)
- Reversible RNA adenosine methylation in biological regulation. (2013) (284)
- Efficient and quantitative high-throughput transfer RNA sequencing (2015) (275)
- Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development (2011) (269)
- Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila. (2008) (257)
- Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine (2012) (242)
- Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth. (2015) (237)
- A small molecule enhances RNA interference and promotes microRNA processing (2008) (226)
- Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA (2008) (219)
- Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine (2011) (216)
- Structural insight into substrate preference for TET-mediated oxidation (2015) (191)
- Blood-brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging. (2014) (174)
- A fluorescent probe for rapid detection of hydrogen sulfide in blood plasma and brain tissues in mice (2012) (173)
- Silver-catalyzed intermolecular amination of C--H groups. (2007) (171)
- Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis (2013) (164)
- A silver-catalyzed intramolecular amidation of saturated C--h bonds. (2004) (164)
- Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum. (2012) (159)
- Efficient gold-catalyzed hydroamination of 1,3-dienes. (2006) (159)
- Recent Advances in Silver-Catalyzed Nitrene, Carbene, and Silylene-Transfer Reactions (2006) (149)
- The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism (2008) (146)
- The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA. (2010) (136)
- An exceptionally selective lead(II)-regulatory protein from Ralstonia metallidurans: development of a fluorescent lead(II) probe. (2005) (136)
- Potential functional roles of DNA demethylation intermediates. (2013) (135)
- Nucleic acid modifications with epigenetic significance. (2012) (127)
- Platinum(II)-catalyzed intramolecular cyclization of o-substituted aryl alkynes through sp3 C-H activation. (2009) (101)
- Addition of heterocycles to electron deficient olefins and alkynes catalyzed by gold(III) (2005) (96)
- Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning (2018) (94)
- Selective recognition of metal ions by metalloregulatory proteins. (2008) (91)
- Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2 (2014) (89)
- Organocatalytic asymmetric direct C(sp3)-H functionalization of ethers: a highly efficient approach to chiral spiroethers. (2012) (85)
- The structure of the human AGT protein bound to DNA and its implications for damage detection. (2005) (82)
- The auxiliary protein complex SaePQ activates the phosphatase activity of sensor kinase SaeS in the SaeRS two‐component system of Staphylococcus aureus (2012) (80)
- Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection (2010) (68)
- Engineering a uranyl-specific binding protein from NikR. (2009) (67)
- The tightly regulated copper window in yeast. (2011) (67)
- m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination (2019) (66)
- Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins. (2006) (65)
- ALKBH4-dependent demethylation of actin regulates actomyosin dynamics (2013) (63)
- The Oxidation-sensing Regulator (MosR) Is a New Redox-dependent Transcription Factor in Mycobacterium tuberculosis* (2012) (62)
- Sprouts of RNA epigenetics (2013) (62)
- UO₂²⁺ uptake by proteins: understanding the binding features of the super uranyl binding protein and design of a protein with higher affinity. (2014) (56)
- Targeting MgrA-mediated virulence regulation in Staphylococcus aureus. (2011) (49)
- Structural insight into the oxidation‐sensing mechanism of the antibiotic resistance of regulator MexR (2010) (44)
- Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing (2013) (44)
- Damage Detection and Base Flipping in Direct DNA Alkylation Repair (2009) (44)
- Aureusimines in Staphylococcus aureus Are Not Involved in Virulence (2010) (44)
- Highly sensitive and selective gold(I) recognition by a metalloregulator in Ralstonia metallidurans. (2009) (43)
- Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein–DNA system (2010) (41)
- A TET Homologue Protein from Coprinopsis cinerea (CcTET) That Biochemically Converts 5-Methylcytosine to 5-Hydroxymethylcytosine, 5-Formylcytosine, and 5-Carboxylcytosine (2014) (40)
- A Non-Heme Iron-Mediated Chemical Demethylation in DNA and RNA (2009) (39)
- Preparation and characterization of the native iron(II)-containing DNA repair AlkB protein directly from Escherichia coli. (2004) (35)
- Staphylococcus aureus CymR Is a New Thiol-based Oxidation-sensing Regulator of Stress Resistance and Oxidative Response* (2012) (34)
- Detection of 5-hydroxymethylcytosine in a combined glycosylation restriction analysis (CGRA) using restriction enzyme Taq(α)I. (2011) (33)
- Spectroscopic insights into lead(II) coordination by the selective lead(II)-binding protein PbrR691. (2007) (32)
- Heterologous expression and purification of Arabidopsis thaliana VIM1 protein: in vitro evidence for its inability to recognize hydroxymethylcytosine, a rare base in Arabidopsis DNA. (2012) (30)
- Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR (2013) (30)
- How do DNA repair proteins locate potential base lesions? a chemical crosslinking method to investigate O6-alkylguanine-DNA alkyltransferases. (2003) (29)
- Fto Plays an Oncogenic Role in Acute Myeloid Leukemia As a N6-Methyladenosine RNA Demethylase (2016) (29)
- METTL14 is essential for β-cell survival and insulin secretion. (2019) (29)
- Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies. (2004) (28)
- Emergence of chemical biology approaches to the RNAi/miRNA pathway. (2010) (27)
- Using the bias from flow to elucidate single DNA repair protein sliding and interactions with DNA. (2009) (24)
- The hunt for 5-hydroxymethylcytosine: the sixth base. (2011) (24)
- Detection of 5‐Hydroxymethylcytosine in DNA by Transferring a Keto‐Glucose by Using T4 Phage β‐Glucosyltransferase (2011) (23)
- Mechanisms of Brønsted Acid Catalyzed Additions of Phenols and Protected Amines to Olefins: A DFT Study (2008) (21)
- A proteomic approach to identification of plutonium-binding proteins in mammalian cells. (2012) (15)
- Gold‐Catalyzed Organic Transformations (2008) (15)
- Gold(I)-Mediated Hydrothiolation of Conjugated Olefins (2007) (14)
- Metal-binding properties of Hpn from Helicobacter pylori and implications for the therapeutic activity of bismuth (2011) (14)
- Binding of ReO4− with an engineered MoO42−-binding protein: towards a new approach in radiopharmaceutical applications (2011) (13)
- Gold(I)-Catalyzed Synthesis of Dihydrobenzofurans from Aryl Allyl Ethers (2006) (12)
- Subsets of Visceral Adipose Tissue Nuclei with Distinct Levels of 5-Hydroxymethylcytosine (2016) (10)
- N 6-Methyladenosine Modification of LncRNA Pvt1 Governs Epidermal Stemness (2020) (10)
- Synthesis of DNA oligos containing 2'-deoxy-2'-fluoro-D-arabinofuranosyl-5-carboxylcytosine as hTDG inhibitor. (2012) (9)
- Silver-Catalyzed Intermolecular Amination of C—H Groups. (2007) (8)
- Nonenzymatic Labeling of 5‐Hydroxymethylcytosine in Nanopore Sequencing (2013) (6)
- Platinum(II)-Catalyzed Intramolecular Cyclization of o-Substituted Aryl Alkynes Through sp3 C—H Activation. (2009) (5)
- Silver‐Catalyzed Nitrene Transfer Reactions (2010) (5)
- Gold ( I )-Catalyzed Synthesis of Dihydrobenzofurans from Aryl Allyl Ethers (2006) (5)
- Gold(III)-Catalyzed Nitrene Insertion into Aromatic and Benzylic C—H Groups. (2008) (4)
- Cover Picture: The AlkB Domain of Mammalian ABH8 Catalyzes Hydroxylation of 5‐Methoxycarbonylmethyluridine at the Wobble Position of tRNA (Angew. Chem. Int. Ed. 47/2010) (2010) (4)
- Selective capture of 5-hydroxymethylcytosine from genomic DNA. (2012) (4)
- Chapter 1 - Silver-Mediated Oxidation Reactions: Recent Advances and New Prospects (2009) (4)
- Gold‐Catalyzed Additions to Alkenes: O‐Nucleophiles (2012) (3)
- A highly sensitive and genetically encoded fluorescent reporter for ratiometric monitoring of quinones in living cells. (2013) (3)
- Gold(I)‐Catalyzed Intra‐ and Intermolecular Hydroamination of Unactivated Olefins. (2006) (3)
- Retraction: Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus (2017) (3)
- Broensted Acid Catalyzed Addition of Phenols, Carboxylic Acids, and Tosylamides to Simple Olefins. (2007) (3)
- Silver-Mediated Oxidation Reactions: Recent Advances and New Prospects (2010) (2)
- Gold-Catalyzed Additions to Alkenes: N-Nucleophiles (2012) (2)
- Abstract PR03: Genome-wide 5-hydroxymethylcytosine profiles in circulating cell-free DNA and survival in patients with multiple myeloma (2020) (2)
- Gold(I)‐Catalyzed Intermolecular Addition of Phenols and Carboxylic Acids to Olefins. (2005) (1)
- Direct Reversal of DNA Alkylation Damage (2006) (1)
- Blockade of Mir-150 Maturation by MLL-Fusion/MYC/Lin-28 Is Required for MLL-Associated Leukemia (2012) (1)
- Gold(I)-Mediated Hydrothiolation of Conjugated Olefins. (2007) (1)
- Kethoxal-assisted single-stranded DNA sequencing (KAS-seq) for capturing transcription dynamics and enhancer activity (2020) (1)
- Bromodomain and Extra-Terminal Motif Proteins (BETs) Mediate 5-Azacitidine Resistance in Myeloid Leukemia through Recruitment of an Active RNA Polymerase II Complex (2016) (1)
- Phosphoglycerate Mutase 1 Promotes Leukemia Metabolism by Coordinating Glycolysis and Biosynthesis, and Represnts a Therapuetic Target in Leukemia Treatment (2012) (1)
- The N6-Adenine Methyltransferase METTL14 Plays an Oncogenic Role in Acute Myeloid Leukemia (2016) (1)
- Targeted Inhibition of STAT/TET1 Axis As a Potent Therapeutic Strategy for Acute Myeloid Leukemia (2017) (0)
- Abstract A39: Concordance of 5-hydroxymethylcytosine-modified genes from circulating cell-free DNA and positron emission tomography in multiple myeloma (2020) (0)
- Gold(I)‐Catalyzed Synthesis of Dihydrobenzofurans from Aryl Allyl Ethers. (2006) (0)
- A Silver-Catalyzed Intramolecular Amidation of Saturated C—H Bonds. (2004) (0)
- Subsets of brain neuronal and visceral adipocyte nuclei with high levels of hydroxymethylcytosine (2017) (0)
- 5hmC Distribution in Isolated Visceral Adipose Tissue Nuclei (2016) (0)
- Abstract 3552: Selective inhibition of copper metabolism as a novel approach to treat triple-negative breast cancer (2017) (0)
- Abstract A025: Assessing the role of bivalency in MYCN-amplified neuroblastoma (2022) (0)
- Titelbild: The AlkB Domain of Mammalian ABH8 Catalyzes Hydroxylation of 5‐Methoxycarbonylmethyluridine at the Wobble Position of tRNA (Angew. Chem. 47/2010) (2010) (0)
- Abstract 5717: Novel evidence for FTO as an oncogenic player and mediator of chemoresistance in colorectal cancer (2022) (0)
- MA21.11 Epigenomic Mapping of Cell-Free DNA in Patients with Non-Small Cell Lung Cancer (2018) (0)
- Abstract 227: Kethoxal-assisted single-stranded DNA sequencing (KAS-seq) reveals dynamic and temporal changes in transcription in response to UVB exposure (2022) (0)
- An Au‐Catalyzed Cyclialkylation of Electron‐Rich Arenes with Epoxides to Prepare 3‐Chromanols. (2004) (0)
- Cyclizations Based on C—H Activation (2010) (0)
- Selective Recognition of Heavy Elements by Protein-Based Reagents (2019) (0)
- HRD1-Mediated METTL14 Degradation Regulates M 6a mRNA Modification to Suppress ER Proteotoxic Liver Damage (2021) (0)
- m6A RNA modification controls transitions between quiescence and proliferation during B cell development (2019) (0)
- Addition of Heterocycles to Electron Deficient Olefins and Alkynes Catalyzed by Gold(III). (2006) (0)
- Oxidative Nucleic Acid Modification and Demodification (2012) (0)
- Abstract 460: Base resolution epigenomic analysis reveals a role for Tet2 in modulating enhancer activity (2014) (0)
- Preparation of DNA Containing 5‐Hydroxymethyl‐2′‐Deoxycytidine Modification Through Phosphoramidites with TBDMS as 5‐Hydroxymethyl Protecting Group (2011) (0)
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