Claes Dahlgren
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Swedish professor
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Computer Science
Claes Dahlgren's Degrees
- PhD Computer Science Uppsala University
- Masters Computer Science Uppsala University
- Bachelors Computer Science Uppsala University
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(Suggest an Edit or Addition)Claes Dahlgren's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Respiratory burst in human neutrophils. (1999) (829)
- International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family (2009) (699)
- Mobilization of granules and secretory vesicles during in vivo exudation of human neutrophils. (1995) (313)
- Isoluminol-enhanced chemiluminescence: a sensitive method to study the release of superoxide anion from human neutrophils. (1996) (242)
- Role of myeloperoxidase in luminol-dependent chemiluminescence of polymorphonuclear leukocytes (1983) (241)
- The Synthetic Peptide Trp-Lys-Tyr-Met-Val-Met-NH2 Specifically Activates Neutrophils through FPRL1/Lipoxin A4 Receptors and Is an Agonist for the Orphan Monocyte-expressed Chemoattractant Receptor FPRL2* (2001) (225)
- Galectin-3 activates the NADPH-oxidase in exudated but not peripheral blood neutrophils. (1998) (214)
- Intra- and extracellular events in luminol-dependent chemiluminescence of polymorphonuclear leukocytes (1984) (213)
- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors (2021) (212)
- Histaminergic regulation of NK cells. Role of monocyte-derived reactive oxygen metabolites. (1994) (189)
- Intracellular generation of superoxide by the phagocyte NADPH oxidase: how, where, and what for? (2010) (188)
- Assembly and activation of the neutrophil NADPH oxidase in granule membranes. (2002) (180)
- Ligand recognition and activation of formyl peptide receptors in neutrophils (2006) (172)
- The inhibition of polymorphonuclear leukocyte cytotoxicity by dapsone. A possible mechanism in the treatment of dermatitis herpetiformis. (1978) (162)
- A proinflammatory peptide from Helicobacter pylori activates monocytes to induce lymphocyte dysfunction and apoptosis. (2001) (156)
- The synthetic chemoattractant Trp-Lys-Tyr-Met-Val-DMet activates neutrophils preferentially through the lipoxin A(4) receptor. (2000) (150)
- Host Defense Peptide LL-37 Selectively Reduces Proinflammatory Macrophage Responses (2011) (145)
- Natural killer cell dysfunction and apoptosis induced by chronic myelogenous leukemia cells: role of reactive oxygen species and regulation by histamine. (2000) (134)
- Phorbol myristate acetate‐induced NADPH oxidase activity in human neutrophils: only half the story has been told (1996) (134)
- Characterization of fMet-Leu-Phe receptor-mediated Ca2+ influx across the plasma membrane of human neutrophils. (1986) (131)
- Cyclosporin H, Boc-MLF and Boc-FLFLF are Antagonists that Preferentially Inhibit Activity Triggered Through the Formyl Peptide Receptor (2007) (123)
- Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils. (1999) (122)
- Pattern of formylmethionyl-leucyl-phenylalanine-induced luminol- and lucigenin-dependent chemiluminescence in human neutrophils (1985) (120)
- Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen species. (2015) (119)
- Basic characteristics of the neutrophil receptors that recognize formylated peptides, a danger-associated molecular pattern generated by bacteria and mitochondria. (2016) (116)
- Pneumolysin Released during Streptococcus pneumoniae Autolysis Is a Potent Activator of Intracellular Oxygen Radical Production in Neutrophils (2008) (115)
- Myeloperoxidase modulates the phagocytic activity of polymorphonuclear neutrophil leukocytes. Studies with cells from a myeloperoxidase-deficient patient. (1984) (111)
- Activation of the Neutrophil Nicotinamide Adenine Dinucleotide Phosphate Oxidase by Galectin-11 (2002) (106)
- A hepatitis C virus‐encoded, nonstructural protein (NS3) triggers dysfunction and apoptosis in lymphocytes: role of NADPH oxidase‐derived oxygen radicals (2004) (105)
- Lipopolysaccharide-Induced Gelatinase Granule Mobilization Primes Neutrophils for Activation by Galectin-3 and Formylmethionyl-Leu-Phe (2001) (103)
- Modifications of cellular responses to lysophosphatidic acid and platelet-activating factor by plasma gelsolin. (2007) (99)
- The lysosomal membrane glycoproteins Lamp-1 and Lamp-2 are present in mobilizable organelles, but are absent from the azurophil granules of human neutrophils. (1995) (98)
- Measurement of respiratory burst products generated by professional phagocytes. (2007) (98)
- Different subcellular localization of cytochrome b and the dormant NADPH-oxidase in neutrophils and macrophages: effect on the production of reactive oxygen species during phagocytosis. (1995) (85)
- Measurement of respiratory burst products, released or retained, during activation of professional phagocytes. (2014) (83)
- Lipopolysaccharide-Induced Granule Mobilization and Priming of the Neutrophil Response to Helicobacter pylori Peptide Hp(2-20), Which Activates Formyl Peptide Receptor-Like 1 (2002) (81)
- The Human Neutrophil Subsets Defined by the Presence or Absence of OLFM4 Both Transmigrate into Tissue In Vivo and Give Rise to Distinct NETs In Vitro (2013) (77)
- Difference in extracellular radical release after chemotactic factor and calcium ionophore activation of the oxygen radical-generating system in human neutrophils. (1987) (76)
- The mechanism for activation of the neutrophil NADPH‐oxidase by the peptides formyl‐Met‐Leu‐Phe and Trp‐Lys‐Tyr‐Met‐Val‐Met differs from that for interleukin‐8 (2004) (75)
- Actin Assembly and Regulation of Neutrophil Function: Effects of Cytochalasin B and Tetracaine on Chemotactic Peptide‐Induced O2 ‐ Production and Degranulation (1991) (75)
- Inhibition of Human Leukocyte Metabolism and Random Mobility by Local Anaesthesia (1985) (72)
- Proinflammatory Activity of a Cecropin-Like Antibacterial Peptide from Helicobacter pylori (2001) (72)
- Extracellular release of reactive oxygen species from human neutrophils upon interaction with Escherichia coli strains causing renal scarring (1991) (64)
- Changes in Activation States of Murine Polymorphonuclear Leukocytes (PMN) during Inflammation: a Comparison of Bone Marrow and Peritoneal Exudate PMN (2006) (63)
- Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like‐1 (2008) (63)
- Phagocytosis and hydrophobicity: a method of calculating contact angles based on the diameter of sessile drops. (1981) (61)
- Comparison between luminol- and lucigenindependent chemiluminescence of polymorphonuclear leukocytes. (2009) (61)
- Activation of the oxygen-radical-generating system in granules of intact human neutrophils by a calcium ionophore (ionomycin). (1992) (60)
- Interleukin-8-Derived Peptide Has Antibacterial Activity (2005) (60)
- Neutrophil bactericidal activity against Staphylococcus aureus adherent on biological surfaces. Surface-bound extracellular matrix proteins activate intracellular killing by oxygen-dependent and -independent mechanisms. (1990) (58)
- Serotonin protects NK cells against oxidatively induced functional inhibition and apoptosis (2001) (58)
- Cell surface expression of fMet-Leu-Phe receptors on human neutrophils. Correlation to changes in the cytosolic free Ca2+ level and action of phorbol myristate acetate. (1987) (56)
- The two neutrophil members of the formylpeptide receptor family activate the NADPH-oxidase through signals that differ in sensitivity to a gelsolin derived phosphoinositide-binding peptide (2004) (55)
- Receptor-Dependent and -Independent Immunomodulatory Effects of Phenol-Soluble Modulin Peptides from Staphylococcus aureus on Human Neutrophils Are Abrogated through Peptide Inactivation by Reactive Oxygen Species (2012) (54)
- Localization of human neutrophil interleukin‐8 (CXCL‐8) to organelle(s) distinct from the classical granules and secretory vesicles (2006) (54)
- Characterization of the Luminol‐Amplified Light‐Generating Reaction Induced in Human Monocytes (1989) (54)
- Neutrophil killing of two type 1 fimbria-bearing Escherichia coli strains: dependence on respiratory burst activation (1990) (54)
- Reactivation of Formyl Peptide Receptors Triggers the Neutrophil NADPH-oxidase but Not a Transient Rise in Intracellular Calcium* (2003) (53)
- The Host Defense Peptide LL-37 Selectively Permeabilizes Apoptotic Leukocytes (2008) (52)
- N-Formyl Peptide Receptor 3 (FPR3) Departs from the Homologous FPR2/ALX Receptor with Regard to the Major Processes Governing Chemoattractant Receptor Regulation, Expression at the Cell Surface, and Phosphorylation (2011) (52)
- Phagocyte Activation by Trp–Lys–Tyr–Met–Val–Met, Acting through FPRL1/LXA4R, is not Affected by Lipoxin A4 (2002) (52)
- Neutrophil NADPH‐oxidase activation by an annexin AI peptide is transduced by the formyl peptide receptor (FPR), whereas an inhibitory signal is generated independently of the FPR family receptors (2005) (52)
- Structural Characterization and Inhibitory Profile of Formyl Peptide Receptor 2 Selective Peptides Descending from a PIP2-Binding Domain of Gelsolin (2012) (51)
- Natural killer cell dysfunction and apoptosis induced by chronic myelogenous leukemia cells: role of reactive oxygen species and regulation by histamine (2000) (51)
- Effects of five amino–amide local anaesthetic agents on human polymorphonuclear leukocytes measured by chemiluminescence (1994) (50)
- Human neutrophil migration into skin chambers is associated with ProductionI of NAP‐1/IL8 and C5a (1991) (50)
- Effect of in vitro preincubation of polymorphonuclear leukocytes on formylmethionyl-leucyl-phenylalanine-induced chemiluminescence (1982) (50)
- Intracellular Neutrophil Oxidants: From Laboratory Curiosity to Clinical Reality (2019) (49)
- Particles binding beta(2)-integrins mediate intracellular production of oxidative metabolites in human neutrophils independently of phagocytosis. (1999) (49)
- Oxygen radical‐induced natural killer cell dysfunction: role of myeloperoxidase and regulation by serotonin (2004) (49)
- What Formyl Peptide Receptors, if Any, Are Triggered by Compound 43 and Lipoxin A4? (2011) (47)
- Reactivation of Desensitized Formyl Peptide Receptors by Platelet Activating Factor: A Novel Receptor Cross Talk Mechanism Regulating Neutrophil Superoxide Anion Production (2013) (47)
- The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop. (2013) (47)
- Propofol decreases random and chemotactic stimulated locomotion of human neutrophils in vitro. (1993) (47)
- Calcium-induced translocation of annexins to subcellular organelles of human neutrophils. (1994) (46)
- The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation. (2010) (46)
- FPR2 signaling without &bgr;‐arrestin recruitment alters the functional repertoire of neutrophils (2017) (44)
- Mechanisms in Neutrophil Priming: Characterization of the Oxidative Response Induced by Formylmethionyl‐Leucyl‐Phenylalanine in Human Exudated Cells (1991) (44)
- Lipoxin A4 Metabolites/Analogues from Two Commercial Sources have No Effects on TNF‐α‐mediated Priming or Activation through the Neutrophil Formyl Peptide Receptors (2009) (44)
- Tumour necrosis factor (TNF)‐α primes murine neutrophils when triggered via formyl peptide receptor‐related sequence 2, the murine orthologue of human formyl peptide receptor‐like 1, through a process involving the type I TNF receptor and subcellular granule mobilization (2008) (43)
- A simple chemiluminescence assay for the determination of reactive oxygen species produced by human neutrophils. (1996) (42)
- Influence of antibiotics on formylmethionyl-leucyl-phenylalanine-induced leukocyte chemiluminescence (1987) (42)
- Lipid raft proteome of the human neutrophil azurophil granule (2007) (41)
- An Intact Cytoskeleton is Required for Prolonged Respiratory Burst Activity During Neutrophil Phagocytosis (2001) (41)
- Phenol-Soluble Modulin α Peptide Toxins from Aggressive Staphylococcus aureus Induce Rapid Formation of Neutrophil Extracellular Traps through a Reactive Oxygen Species-Independent Pathway (2017) (41)
- A novel receptor cross-talk between the ATP receptor P2Y2 and formyl peptide receptors reactivates desensitized neutrophils to produce superoxide. (2014) (40)
- Analysis of horseradish peroxidase-amplified chemiluminescence produced by human neutrophils reveals a role for the superoxide anion in the light emitting reaction. (1988) (40)
- Localization of the luminol-dependent chemiluminescence reaction in human granulocytes. (1989) (39)
- Neutrophil control of formylmethionyl-leucyl-phenylalanine induced mobilization of secretory vesicles and NADPH-oxidase activation: effect of an association of the ligand-receptor complex to the cytoskeleton. (1994) (38)
- Structural changes of the ligand and of the receptor alters the receptor preference for neutrophil activating peptides starting with a formylmethionyl group. (2015) (37)
- Histamine Inhibits Neutrophil NADPH Oxidase Activity Triggered by the Lipoxin A4 Receptor‐Specific Peptide Agonist Trp‐Lys‐Tyr‐Met‐Val‐Met (2003) (37)
- Surface‐related triggering of the neutrophil respiratory burst. Characterization of the response induced by IgG adsorbed to hydrophilic and hydrophobic glass surfaces (1997) (37)
- Is lysosomal fusion required for the granulocyte chemiluminescence reaction? (1989) (36)
- The peptide Trp-Lys-Tyr-Met-Val-D-Met activates neutrophils through the formyl peptide receptor only when signaling through the formylpeptide receptor like 1 is blocked. A receptor switch with implications for signal transduction studies with inhibitors and receptor antagonists. (2006) (36)
- Activation of human neutrophils by mycobacterial phenolic glycolipids (1999) (36)
- Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes (2017) (36)
- Phagocyte-derived reactive oxygen species as suppressors of inflammatory disease. (2008) (36)
- Neutrophil secretory vesicles are the intracellular reservoir for GPI‐80, a protein with adhesion‐regulating potential (2001) (35)
- COMPARISON BETWEEN THE LUMINOL‐DEPENDENT CHEMILUMINESCENCE OF POLYMORPHONUCLEAR LEUKOCYTES AND OF THE MYELOPEROXIDASE‐HOOH SYSTEM: INFLUENCE OF pH, CATIONS AND PROTEIN (1985) (35)
- The Annexin I Sequence Gln9-Ala10-Trp11-Phe12 Is a Core Structure for Interaction with the Formyl Peptide Receptor 1* (2010) (35)
- The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment (2016) (35)
- Difference in neutrophil cytokine production induced by pathogenic and non‐pathogenic mycobacteria (2002) (34)
- Stable formyl peptide receptor agonists that activate the neutrophil NADPH-oxidase identified through screening of a compound library. (2011) (34)
- Subinhibitory Concentrations of the Deformylase Inhibitor Actinonin Increase Bacterial Release of Neutrophil-Activating Peptides: a New Approach to Antimicrobial Chemotherapy (2003) (34)
- Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils (2004) (34)
- Characteristics of the granulocyte chemiluminescence reaction following an interaction between human neutrophils and Salmonella typhimurium bacteria (1988) (33)
- House dust mite allergen activates human eosinophils via formyl peptide receptor and formyl peptide receptor‐like 1 (2007) (33)
- Modulation of polymorphonuclear leukocyte chemiluminescent response to the chemoattractant f-Met-Leu-Phe. (1982) (33)
- Desensitization of formyl peptide receptors is abolished in calcium ionophore-primed neutrophils: an association of the ligand-receptor complex to the cytoskeleton is not required for a rapid termination of the NADPH-oxidase response. (1998) (33)
- Similarities and differences between the responses induced in human phagocytes through activation of the medium chain fatty acid receptor GPR84 and the short chain fatty acid receptor FFA2R. (2018) (33)
- CFP-10 from Mycobacterium tuberculosis Selectively Activates Human Neutrophils through a Pertussis Toxin-Sensitive Chemotactic Receptor (2014) (33)
- Escherichia coli-induced activation of neutrophil NADPH-oxidase: lipopolysaccharide and formylated peptides act synergistically to induce release of reactive oxygen metabolites (1995) (32)
- Difference in hydrogen peroxide release between human neutrophils and neutrophil cytoplasts following calcium ionophore activation. A role of the subcellular granule in activation of the NADPH-oxidase in human neutrophils? (1989) (32)
- Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators—What is the Evidence so far? (2022) (31)
- The phagocyte chemiluminescence paradox: luminol can act as an inhibitor of neutrophil NADPH-oxidase activity. (1999) (30)
- Neutrophil Signaling That Challenges Dogmata of G Protein-Coupled Receptor Regulated Functions. (2020) (30)
- Intracellular production of reactive oxygen species in human neutrophils following activation by the soluble stimuli FMLP, dioctanoylglycerol and ionomycin (1991) (29)
- The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but triggers no unique pathway for opening of plasma membrane calcium channels. (2009) (29)
- Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists. (2013) (29)
- Physicochemical and functional changes in human leukemic cell line HL‐60 (1982) (29)
- Formyl Peptide Receptors in Mice and Men: Similarities and Differences in Recognition of Conventional Ligands and Modulating Lipopeptides. (2018) (28)
- A simple fluorescence technique to stain the plasma membrane of human neutrophils (2004) (28)
- Desensitization of the fMLP‐induced NADPH‐oxidase response in human neutrophils is lacking in okadaic acid‐treated cells (1997) (28)
- P2Y2 receptor signaling in neutrophils is regulated from inside by a novel cytoskeleton-dependent mechanism. (2015) (27)
- A Pepducin Derived from the Third Intracellular Loop of FPR2 Is a Partial Agonist for Direct Activation of This Receptor in Neutrophils But a Full Agonist for Cross-Talk Triggered Reactivation of FPR2 (2014) (27)
- Oxygen radical production and severity of the Guillain–Barré syndrome (2007) (27)
- Interaction of liposomes with polymorphonuclear leukocytes. II. Studies on the consequences of interaction. (1977) (26)
- The Calcium Ionophore Ionomycin can Prime, but not Activate, the Reactive Oxygen Generating System in Differentiated HL‐60 Cells (1989) (26)
- Reactivation of Gαi‐coupled formyl peptide receptors is inhibited by Gαq‐selective inhibitors when induced by signals generated by the platelet‐activating factor receptor (2017) (26)
- The FPR2-induced rise in cytosolic calcium in human neutrophils relies on an emptying of intracellular calcium stores and is inhibited by a gelsolin-derived PIP2-binding peptide (2010) (26)
- Outer membrane protein A deficient Escherichia coli activates neutrophils to produce superoxide and shows increased susceptibility to antibacterial peptides. (2003) (26)
- In vivo‐transmigrated human neutrophils are resistant to antiapoptotic stimulation (2011) (26)
- Priming of human neutrophils by mycobacterial lipoarabinomannans: role of granule mobilisation. (2001) (25)
- N-acetylcysteine enhances receptor-mediated phagocytosis by human neutrophils. (1992) (25)
- Exudate polymorphonuclear leukocytes isolated from skin chambers are primed for enhanced response to subsequent stimulation with chemoattractant f-Met-Leu-Phe and C3-opsonized yeast particles (1988) (25)
- Neutrophil priming that turns natural FFA2R agonists into potent activators of the superoxide generating NADPH‐oxidase (2018) (25)
- Cleavage of annexin I in human neutrophils is mediated by a membrane-localized metalloprotease. (1999) (25)
- The proteolytically stable peptidomimetic Pam-(Lys-βNSpe)6-NH2 selectively inhibits human neutrophil activation via formyl peptide receptor 2. (2015) (25)
- Functional selective ATP receptor signaling controlled by the free fatty acid receptor 2 through a novel allosteric modulation mechanism (2019) (25)
- Newcastle disease virus neuraminidase primes neutrophils for stimulation by galectin-3 and formyl-Met-Leu-Phe. (2004) (25)
- The chemoattractant Trp‐Lys‐Tyr‐Met‐Val‐D‐Met activates eosinophils through the formyl peptide receptor and one of its homologues, formyl peptide receptor‐like 1 (2002) (24)
- A methodological approach to studies of desensitization of the formyl peptide receptor: Role of the read out system, reactive oxygen species and the specific agonist used to trigger neutrophils. (2010) (24)
- The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist. (2008) (23)
- Neutrophils in mucosal secretion are functionally active (1996) (23)
- Translocation of annexin XI to neutrophil subcellular organelles. (1997) (23)
- Divergent Effects on Phagocytosis by Macrophage-Derived Oxygen Radicals (2009) (23)
- A neutrophil inhibitory pepducin derived from FPR1 expected to target FPR1 signaling hijacks the closely related FPR2 instead (2015) (23)
- Phagocyte killing of Campylobacter jejuni in relation to oxidative activation (1992) (23)
- Phagocytic recognition mechanisms in human granulocytes and Acanthamoeba castellanii using type 1 fimbriated Escherichia coli as phagocytic prey (1987) (23)
- Anti‐Granulocyte Antibodies (C‐ANCA, P‐ANCA, GS‐ANA) Studied by Confocal Scanning Laser Fluorescence Microscopy, ELISA, and Chemiluminescence Techniques (1991) (23)
- Myeloperoxidase reduces the opsonizing activity of immunoglobulin G and complement component C3b. (1984) (23)
- The non-steroidal anti-inflammatory drug piroxicam blocks ligand binding to the formyl peptide receptor but not the formyl peptide receptor like 1. (2007) (22)
- Phagocytosis following Translocation of the Neutrophil b‐Cytochrome from the Specific Granule to the Plasma Membrane is Associated with an Increased Leakage of Reactive Oxygen Species (1992) (22)
- Alleviating oxidative stress in cancer immunotherapy: a role for histamine? (2000) (22)
- Chemotactic Factor Binding and Functional Capacity: A Comparison Between Human Granulocytes and Differentiated HL‐60 Cells (1987) (22)
- Staphylococcus aureus–Derived PSMα Peptides Activate Neutrophil FPR2 but Lack the Ability to Mediate β-Arrestin Recruitment and Chemotaxis (2019) (22)
- Defective chemiluminescence response in differentiated HL60 cells due to impaired degranulation. (1986) (22)
- Differentiation of human peripheral blood monocytes to macrophages is associated with changes in the cellular respiratory burst activity (1992) (22)
- Influence of different luminols on the characteristics of the chemiluminescence reaction in human neutrophils. (1995) (21)
- Human neutrophil chemiluminescence and f‐Meth‐Leu‐Phe receptor exposure in bacterial infections (1989) (21)
- Olfactomedin‐4 autoantibodies give unusual c‐ANCA staining patterns with reactivity to a subpopulation of neutrophils (2015) (20)
- Quantification of heterotypic granule fusion in human neutrophils by imaging flow cytometry (2015) (20)
- A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1. (2012) (20)
- A pepducin designed to modulate P2Y2R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk mechanism. (2016) (20)
- Altered O2-/H2O2 production ratio by in vitro and in vivo primed human neutrophils. (1990) (20)
- Interdependent allosteric free fatty acid receptor 2 modulators synergistically induce functional selective activation and desensitization in neutrophils. (2020) (19)
- The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2 Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase* (2016) (19)
- Changes in the ratio between FPR and FPRL1 triggered superoxide production in human neutrophils-a tool in analysing receptor specific events. (2008) (18)
- Molecular docking of 2-(benzimidazol-2-ylthio)-N-phenylacetamide-derived small-molecule agonists of human formyl peptide receptor 1 (2012) (18)
- Analysis of luminol-dependent chemiluminescence from granule depleted neutrophil cytoplasts reveals two different light-emitting mechanisms. (1988) (18)
- Mitocryptides from Human Mitochondrial DNA–Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling Properties (2018) (18)
- A Bactericidal Cecropin-A Peptide with a Stabilized α-Helical Structure Possess an Increased Killing Capacity But No Proinflammatory Activity (2004) (18)
- Interaction between human polymorphonuclear leukocytes and Chlamydia trachomatis (1984) (17)
- Okadaic acid inhibits the signal responsible for activation of the NADPH‐oxidase in neutrophils stimulated with serum‐opsonized yeast (1996) (17)
- Neutrophil alkaline phosphatase activity increase in bacterial infections is not associated with a general increase in secretory vesicle membrane components (1995) (17)
- Human macrophages limit oxidation products in low density lipoprotein (2005) (17)
- Antibacterial Activity of Pepducins, Allosterical Modulators of Formyl Peptide Receptor Signaling (2014) (16)
- Ionomycin-induced neutrophil NADPH oxidase activity is selectively inhibited by the serine protease inhibitor diisopropyl fluorophosphate. (2002) (16)
- Polymorphonuclear leukocyte chemiluminescence induced by formylmethionyl-leucyl-phenylalanine and phorbol myristate acetate: Effects of catalase and superoxide dismutase (1987) (16)
- Measurement of Respiratory Burst Products, Released or Retained, During Activation of Professional Phagocytes. (2019) (15)
- Neutrophil recruitment to inflamed joints can occur without cellular priming (2019) (15)
- Diverse effects of different neutrophil organelles on truncation and membrane-binding characteristics of annexin I. (1996) (15)
- NON-SPECIFIC AND SPECIFIC RECOGNITION MECHANISMS OF BACTERIAL AND MAMMALIAN CELL MEMBRANES (1985) (15)
- The peptidomimetic Lau-(Lys-βNSpe)6-NH2 antagonizes formyl peptide receptor 2 expressed in mouse neutrophils. (2016) (15)
- DPI Selectively Inhibits Intracellular NADPH Oxidase Activity in Human Neutrophils (2019) (15)
- A skin chamber technique as a human model for studies of aseptic inflammatory reactions. (2007) (14)
- Combining Elements from Two Antagonists of Formyl Peptide Receptor 2 Generates More Potent Peptidomimetic Antagonists. (2017) (14)
- Neutrophil function in psoriasis: effects of retinoids. (1987) (14)
- Phagocytosis by lipopolysaccharide-primed human neutrophils is associated with increased extracellular release of reactive oxygen metabolites (1992) (14)
- Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949. (2019) (14)
- Different expression and mobilisation of the complement regulatory proteins CD35, CD55 and CD59 in neonatal and adult neutrophils. (1997) (14)
- Physicochemical surface changes on phagocytic cells during differentiation in relation to chemotaxis and phagocytosis. (1982) (14)
- Isolation by calcium-dependent translation to neutrophil-specific granules of a 42-kD cytosolic protein, identified as being a fragment of annexin XI. (1996) (14)
- Inhibition of polymorphonuclear leucocyte locomotion by surface-bound antigen-antibody complexes. (1983) (13)
- Complement factor adsorption on solid surfaces--an ellipsometric method for investigation of quantitative aspects. (1984) (13)
- Different glycosphingolipid composition in human neutrophil subcellular compartments (2001) (13)
- Collection of in vivo transmigrated neutrophils from human skin. (2014) (13)
- Structure–Function Characteristics and Signaling Properties of Lipidated Peptidomimetic FPR2 Agonists: Peptoid Stereochemistry and Residues in the Vicinity of the Headgroup Affect Function (2019) (13)
- Data on human neutrophil activation induced by pepducins with amino acid sequences derived from β2AR and CXCR4 (2016) (13)
- A Monocyte-Specific Peptide from Herpes Simplex Virus Type 2 Glycoprotein G Activates the NADPH-Oxidase but Not Chemotaxis through a G-Protein-Coupled Receptor Distinct from the Members of the Formyl Peptide Receptor Family1 (2007) (13)
- Formylated MHC Class Ib Binding Peptides Activate Both Human and Mouse Neutrophils Primarily through Formyl Peptide Receptor 1 (2016) (12)
- Effect of hyaluronic acid on polymorphonuclear leucocyte cell surface properties. (2009) (12)
- Modulation of the locomotion of polymorphonuclear leukocytes by a synthetic amphiphile, poly(ethyleneglycol) palmitate. (1979) (12)
- Effect of different inhibitors on the intracellularly and extracellularly generated chemiluminescence induced by formylmethionyl-leucyl-phenylalanine in polymorphonuclear leukocytes. Cellular response in the presence of mannitol, benzoate, taurine, indomethacin and NDGA. (1991) (12)
- Degranulation in human neutrophils primes the cells for subsequent responsiveness to the chemoattractant N-formylmethionylleucylphenylalanine but does not increase the sensitivity of the NADPH-oxidase to an intracellular calcium rise. (1990) (11)
- Relationship between intracellularly and extracellularly generated oxygen metabolites from primed polymorphonuclear leukocytes differs from that obtained from nonprimed cells (1989) (11)
- Concentration gradients in the under-agarose chemotaxis assay system with attractant surface adsorption. (1984) (11)
- Effects on extra- and intracellularly localized, chemoattractant-induced, oxygen radical production in neutrophils following modulation of conditions for ligand-receptor interaction (1988) (11)
- A Rise in Ionized Calcium Activates the Neutrophil NADPH-Oxidase But Is Not Sufficient to Directly Translocate Cytosolic p47phox or p67phox to b Cytochrome Containing Membranes (1997) (11)
- Turning chemoattractant receptors on and off with conventional ligands and allosteric modulators: recent advances in formyl peptide receptor signaling and regulation (2014) (11)
- The limitation of the human neutrophil chemiluminescence response by extracellular peroxidase is stimulus dependent: effect of added horse radish peroxidase on the response induced by both soluble and particulate stimuli. (1988) (11)
- Identification of the lysosomal membrane glycoprotein Lamp-1 as a receptor for type-1-fimbriated (mannose-specific) Escherichia coli. (1996) (10)
- Characteristics of Individual Polymorphonuclear Leucocyte Motility Obtained with a New Opto‐electronic Method (1979) (10)
- Interplay between signaling via the formyl peptide receptor (FPR) and chemokine receptor 3 (CCR3) in human eosinophils (2009) (10)
- Quantitative slot-blot chemiluminescence assay for determination of myeloperoxidase from human granulocytes. (1993) (10)
- Simulation of a metabolic response in vitro between neutrophils and a meningococcal culture filtrate. (1987) (10)
- Identification of Residues Critical for FPR2 Activation by the Cryptic Peptide Mitocryptide-2 Originating from the Mitochondrial DNA–Encoded Cytochrome b (2019) (9)
- Ability of Monocyte-Derived Dendritic Cells To Secrete Oxygen Radicals in Response to Formyl Peptide Receptor Family Agonists Compared to That of Myeloid and Plasmacytoid Dendritic Cells (2007) (9)
- Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949 (2019) (9)
- The synthetic non‐toxic drug 2,3‐dimethyl‐6(2‐dimethylaminoethyl)‐6H‐indolo‐(2,3‐b)quinoxaline inhibits neutrophil production of reactive oxygen species (1999) (9)
- The two neutrophil plasma membrane markers alkaline phosphatase and HLA class I antigen localize differently in granule-deficient cytoplasts. An ideal plasma membrane marker in human neutrophils is still lacking. (2007) (9)
- Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question (2017) (9)
- Comparison of contact angles calculated from the diameter of sessile drops and submerged air bubbles in contact with a solid surface (1986) (9)
- Endogenous cleavage of annexin I generates a truncated protein with a reduced calcium requirement for binding to neutrophil secretory vesicles and plasma membrane. (2000) (8)
- Deactivation of leucocyte chemotaxis in vivo. Locomotion of cells isolated from a patient with meningococcal meningitis. (2009) (8)
- A quantitative microassay for leukocyte chemotaxis, using a microscopic slide system with complement-activating yeast particles as gradient source. (1983) (8)
- QUANTIFICATION OF ANNEXIN I IN SUBCELLULAR FRACTIONS OF HUMAN NEUTROPHILS REVEALS AN EXCLUSIVE CYTOSOLIC LOCALISATION (2001) (8)
- The anionic amphiphile SDS is an antagonist for the human neutrophil formyl peptide receptor 1. (2010) (8)
- Multiple ligand recognition sites in free fatty acid receptor 2 (FFA2R) direct distinct neutrophil activation patterns. (2021) (7)
- Superoxide production and chemiluminescence induced in differentiated HL-60 cells by the chemoattractant formyl-methionyl-leucyl-phenylalanine. (1986) (7)
- A new chemiluminescence paradox: selective inhibition of isoluminol-amplified activity in phagocytes by peptides from annexin AI. (2008) (7)
- Detection of glycoprotein receptors on blotting membranes by binding of live bacteria and amplification by growth. (1995) (7)
- Serum protects against azurophil granule dependent down-regulation of complement receptor type 1 (CR1) on human neutrophils (1995) (7)
- Increased respiratory burst response and alkaline phosphatase activity in human cord blood neutrophils (1992) (7)
- Chemoattractant-induced NADPH oxidase activity in human monocytes is terminated without any association of receptor-ligand complex to cytoskeleton (1995) (7)
- Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis. (2020) (7)
- Temporal adaptation of human neutrophil metabolic responsiveness to the peptide formylmethionyl‐leucyl phenylalanine: A comparison between human neutrophils and granule‐depleted neutrophil cytoplasts (1990) (6)
- Allosteric receptor modulation uncovers an FFA2R antagonist as a positive orthosteric modulator/agonist in disguise. (2021) (6)
- Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty Acids (2021) (6)
- Distinct patterns of granulocyte luminol-dependent chemiluminescence response to lectins WGA and RCA-I (1988) (6)
- Function of exudate neutrophils from skin in psoriasis. (1988) (6)
- Neutrophil Secretion Induced by an Intracellular Ca2+ Rise and Followed by Whole-Cell Patch-Clamp Recordings Occurs Without any Selective Mobilization of Different Granule Populations (2006) (6)
- The PAR4-derived pepducin P4Pal10 lacks effect on neutrophil GPCRs that couple to Gαq for signaling but distinctly modulates function of the Gαi-coupled coupled FPR2 and FFAR2. (2020) (5)
- Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis (2020) (5)
- Cell Surface Expression of fMet-Leu-Phe Receptors on Human Neutrophils Correlation to Changes in the Cytosolic Free Ca 2 ' Level and Action of Phorbol Myristate Acetate (2013) (5)
- Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2-complex (2020) (5)
- Characteristics of the phagocytic process assessed by Coulter Counter. (2009) (5)
- Cultured Rat and Purified Human Pneumocystis carinii Stimulate Intra‐but not Extracellular Free Radical Production in Human Neutrophils (1998) (5)
- Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE mutations (2019) (5)
- Lateral diffusion of wheat germ agglutinin-labeled glycoconjugates in the membrane of differentiating HL-60 and U-937 cells assessed with fluorescence recovery after photobleaching (FRAP) (1983) (5)
- Effect ofN-formylated methionyl-phenylalanine (FMP) and methionyl-leucyl-phenylalanine (FMLP) on gut permeability (1985) (5)
- G protein coupled pattern recognition receptors expressed in neutrophils: Recognition, activation/modulation, signaling and receptor regulated functions (2022) (5)
- Luminol-amplified chemiluminescence activity in human monocytes: a comparison with the activity induced in granulocytes. (1990) (5)
- The adherence of polymorphonuclear leucocytes to an albumin-coated glass surface. Effects of therapeutic concentrations of the Catharantus derivatives vincristine, vinblastine and vindesine. (2009) (4)
- The serine protease inhibitor diisopropylfluorophosphate inhibits neutrophil NADPH-oxidase activity induced by the calcium ionophore ionomycin and serum opsonised yeast particles (1995) (4)
- Chemotaxis of polymorphonuclear leukocytes in response to surface-bound complement-derived chemoattractants generated in situ (1984) (4)
- Re.: The choice of agarose in the under-agarose assay critically affects neutrophil locomotion. (1986) (4)
- Serotonergic Regulation of Natural Killer Cells: A Minireview (1993) (4)
- Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2 complex (2020) (4)
- Modulation of polymorphonuclear leukocyte locomotion by synthetic amphiphiles (1980) (3)
- Modulation of polymorphonuclear leukocyte locomotion by synthetic amphiphiles: effect of saturated fatty acid esters (C2-C18) of poly(ethyleneglycol) 6000. (1980) (3)
- GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by β-arrestin recruiting GPR84 agonists. (2022) (3)
- Metalloproteinase Inhibitors Increase the Survival of Long-Term Refrigerated Platelets in Mice. (2007) (3)
- Physiochemical properties of polymorphonuclear leukocyte surface structures associated with the f-Met-Leu-Phe receptor (1982) (2)
- Doxycycline effects on the adherence of polymorphonuclear leukocytes to an albumin-coated glass surface. (1987) (2)
- An attempt to design an isoluminol-hydrogen peroxidase-amplified CL that measures intracellularly produced H2O2 in phagocytes: sensitivity for H2O2 is not high enough to allow detection. (2007) (2)
- Problems in identifying microbial-derived neutrophil activators, focusing on Helicobacter pylori. (2002) (2)
- Antimicrobial Host Defence Peptides of Human Neutrophils – Roles in Innate Immunity (2008) (2)
- Lack of myeloperoxidase-mediated iodination in granulocytes from a patient with generalized pustular psoriasis (1979) (2)
- Factor-specific deactivation of leucocyte chemotaxis in vivo. (2009) (2)
- Structural Determinants in the Staphylococcus aureus–Derived Phenol-Soluble Modulin α2 Peptide Required for Neutrophil Formyl Peptide Receptor Activation (2022) (1)
- Formylpeptide receptors in GtoPdb v.2021.2 (2021) (1)
- Formyl Peptide Receptor Family Receptor Distinct from the Members of the Chemotaxis through a G-Protein-Coupled Activates the NADPH-Oxidase but Not Simplex Virus Type 2 Glycoprotein G A Monocyte-Specific Peptide from Herpes (2007) (1)
- The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs (2023) (1)
- Multiple ligand recognition sites in free fatty acid receptor 2 (FFAR2) direct distinct neutrophil activation patterns (2020) (1)
- Selective Modulation of a Chemotactic Receptor in HL-60 Cells by Retinoic Acid1 (1985) (1)
- Influence of fluid-phase chemoattractants on polymorphonuclear leukocyte chemotaxic responsiveness to a surface-bound attractant (1985) (1)
- Structural determinants in the Staphylococcus aureus derived phenol-soluble modulin α2 peptide required for neutrophil formyl peptide receptor activation (2021) (1)
- Human Plasma Gelsolin Inhibits Cellular Responses to Platelet Activating Factor (PAF). (2005) (1)
- The putative Gαq-inhibiting pepducin P4Pal10 distinctly modulates function of the Gαi-coupled receptors FPR2 and FFA2R in neutrophils (2019) (1)
- Modulation of granulocyte response to the chemoattractant F-Met-Leu-Phe. (1982) (1)
- Signals Generated by Neutrophil Receptors for Danger Molecules Transactivate Allosterically Modulated FFA2R: Distinct response patterns are mediated by modulators recognized by different allosteric receptor sites (2022) (1)
- Interdependent Allosteric FFA2R Modulators Synergistically Induce Functional Selective Activation and Desensitization in Neutrophils (2019) (1)
- Data showing effects of a PI3K-δ inhibitor on neutrophil superoxide production during FPR2 activation and reactivation (2020) (1)
- Cell Surface Expression of fMet-Leu-Phe Receptors (0)
- Poster 57 Leukocyte Function in Mucosal Secretion (1995) (0)
- AB0067 Allosteric receptor modulation of a free fatty acid receptor turns natural agonists into potent activators of the superoxide generating neutrophil nadph-oxidase (2018) (0)
- Antibacterial Activity of Pepducins, Allosterical Modulators of (2014) (0)
- ResponsesReduces Proinflammatory Macrophage Host Defense Peptide LL-37 Selectively (2011) (0)
- Allosteric receptor modulation uncovers an FFAR2 antagonist as a positive orthosteric modulator/agonist in disguise (2021) (0)
- Receptor Signaling Allosterical Modulators of Formyl Peptide Antibacterial Activity of Pepducins (2014) (0)
- An increase in the cytosolic concentration of free calcium ions activates the neutrophil NADPH-oxidase provided that the free fatty acid receptor 2 has been allosterically modulated. (2023) (0)
- Posters: Free Radicals (2014) (0)
- AproinflammatorypeptidefromHelicobacter pylori activatesmonocytestoinducelymphocytedysfunctionandapoptosis (2006) (0)
- Subject Index Vol. 1, 2009 (2009) (0)
- The ketone body acetoacetate activates human neutrophils through FFA2R (2022) (0)
- Formylpeptide receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
- Contents, Vol. 85, 1988 (2004) (0)
- DISTINCT BEHAVIOUR OF N-FORMYL PEPTIDE RECEPTOR 2 (FPR2) AND 3 (FPR3) WITH REGARD TO PHOSPHORYLATION AND INTERNALIZATION (2011) (0)
- Phagocyte-derived reactive oxygen species as suppressors of inflammation (2009) (0)
- Locomotion and adhesion of polymorphonuclear leukocytes effects of the supporting substratum (1982) (0)
- Pro- and anti-oxidative activities of human monocytes: Effect of concentration of oxidatively modified low density lipoprotein (2000) (0)
- Coagulation and fibrinolysis factors in patients having the microembolism syndrome (1974) (0)
- Cytotoxic Peptides from S. aureus Cause Neutrophil Cell Death with NET-like Features (2014) (0)
- The Allosterically Modulated Free Fatty Acid Receptor 2 is Transactivated by an Increase in the Cytosolic Concentration of Calcium Ions (2022) (0)
- Research letterInteraction between human polymorphonuclear leukocytes and Chlamydia trachomatis (1984) (0)
- Secretion of type-1-fimbriae binding proteins from human neutrophil granulocytes (1996) (0)
- Adenine Dinucleotide Phosphate Oxidase by Activation of the Neutrophil Nicotinamide (2013) (0)
- Phenol-soluble modulin α and β display divergent roles in mice with staphylococcal septic arthritis (2022) (0)
- Chemotherapy Peptides : a New Approach to Antimicrobial Bacterial Release of Neutrophil-Activating Deformylase Inhibitor Actinonin Increase Subinhibitory Concentrations of the (2003) (0)
- Human Neutrophils Major Galectin-3 Receptor Candidates in Identification of CD 66 a and CD 66 b as the Leffler (1999) (0)
- Allosteric receptor modulation of FFA2R turns natural agonists into potent activators of the superoxide generating neutrophil NADPH-oxidase (2018) (0)
- Endogenous Serum Amyloid A Lacks Proinflammatory Activity in Circulation [Supplementary material] (2010) (0)
- CYTOCHROME CONTAINING MEMBRANES (0)
- Function and regulation of GPR84 in human neutrophils. (2023) (0)
- A solid-phase method for protein determination (1989) (0)
- PHYSIOCHEMICAL PROPERTIES OF POLYMORPHONUCLEA R LEUKOCYTE (1982) (0)
- AZ2158 is a more potent formyl peptide receptor 1 inhibitor than the commonly used peptide antagonists in abolishing neutrophil chemotaxis. (2023) (0)
- Contents Vol. 1, 2009 (2009) (0)
- Galectin-1 Adenine Dinucleotide Phosphate Oxidase by Activation of the Neutrophil Nicotinamide Karlsson (2002) (0)
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