Clark Kenneth Colton
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Clark Kenneth Coltonengineering Degrees
Engineering
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Biomedical Engineering
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Engineering
Why Is Clark Kenneth Colton Influential?
(Suggest an Edit or Addition)Clark Kenneth Colton's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Implantable biohybrid artificial organs. (1995) (433)
- Effect of Hypoxia on Insulin Secretion by Isolated Rat and Canine Islets of Langerhans (1993) (423)
- A CONCENTRATION POLARIZATION MODEL FOR THE FILTRATE FLUX IN CROSS-FLOW MICROFILTRATION OF PARTICULATE SUSPENSIONS (1986) (347)
- The osmotic pressure of concentrated protein solutions: Effect of concentration and ph in saline solutions of bovine serum albumin (1981) (316)
- Restricted diffusion in liquids within fine pores (1973) (247)
- Transplantation of human islets without immunosuppression (2013) (231)
- Kinetics of hemodiafiltration. I. In vitro transport characteristics of a hollow-fiber blood ultrafilter. (1975) (222)
- Bioengineering in development of the hybrid artificial pancreas. (1991) (214)
- Kinetics of hemodiafiltration. II. Clinical characterization of a new blood cleansing modality. (1975) (196)
- The distribution of labeled low-density lipoproteins across the rabbit thoracic aorta in vivo. (1977) (180)
- Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist (2012) (165)
- Effect of External Oxygen Mass Transfer Resistances on Viability of Immunoisolated Tissue a (1997) (150)
- Enhanced Oxygen Supply Improves Islet Viability in a New Bioartificial Pancreas (2013) (150)
- Permeability of solutes through hydrated polymer membranes. Part III. Theoretical background for the selectivity of dialysis membranes (1969) (148)
- Implantable Biohybrid Artificial Organs (1995) (147)
- Permeability of dialyzer membranes to TNFα-inducing substances derived from water bacteria (1992) (146)
- Human Islet Oxygen Consumption Rate and DNA Measurements Predict Diabetes Reversal in Nude Mice (2007) (143)
- Artificial pancreas using living beta cells:. effects on glucose homeostasis in diabetic rats. (1977) (141)
- Quantitative analysis of cell composition and purity of human pancreatic islet preparations (2010) (138)
- Permeability studies with cellulosic membranes. (1971) (133)
- The Distribution of Labeled Albumin across the Rabbit Thoracic Aorta in Vivo (1977) (120)
- Oxygen supply to encapsulated therapeutic cells. (2014) (113)
- Long-Term Normoglycemia in Rats Receiving Transplants with Encapsulated Islets (2005) (108)
- A stirred microchamber for oxygen consumption rate measurements with pancreatic islets (2007) (106)
- The Efficacy of an Immunoisolating Membrane System for Islet Xenotransplantation in Minipigs (2013) (97)
- Effect of oxygen on isolated pancreatic tissue. (1989) (95)
- Islet assessment for transplantation (2009) (93)
- Time course of membrane microarchitecture-driven neovascularization. (1996) (93)
- Local Variation in Arterial Wall Permeability to Low Density Lipoprotein in Normal Rabbit Aorta (1986) (92)
- Rat islet cell aggregates are superior to islets for transplantation in microcapsules (2010) (92)
- Effect of diffusional limitations on lineweaver‐burk plots for immobilized enzymes (1974) (87)
- Function and survival of macroencapsulated syngeneic islets transplanted into streptozocin-diabetic mice. (1998) (83)
- Pancreas oxygenation is limited during preservation with the two-layer method. (2005) (83)
- Improved Vascularization of Planar Membrane Diffusion Devices following Continuous Infusion of Vascular Endothelial Growth Factor (2000) (82)
- Analysis of membrane processes for blood purification. (1987) (80)
- An analysis of carrier‐facilitated transport (1973) (79)
- Protein A immunoaffinity hollow fiber membranes for immunoglobulin G purification: experimental characterization. (1995) (76)
- Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes (2017) (74)
- Diffusion and partitioning of macromolecules within finely porous glass (1975) (74)
- Reversal of hyperglycemia in mice after subcutaneous transplantation of macroencapsulated islets. (1999) (73)
- ISLETS IN ALGINATE MACROBEADS REVERSE DIABETES DESPITE MINIMAL ACUTE INSULIN SECRETORY RESPONSES1 (2001) (73)
- Effects of oxygen on mouse embryonic stem cell growth, phenotype retention, and cellular energetics. (2008) (72)
- Continuous flow membrane filtration of plasma from whole blood. (1978) (70)
- Laminar flow mass transfer in a flat duct with permeable walls (1971) (69)
- Ultrafiltration of lipoproteins through a synthetic membrane. Implications for the filtration theory of atherogenesis. (1972) (67)
- The effects of low oxygen on self-renewal and differentiation of embryonic stem cells (2009) (67)
- High-density culture of human islets on top of silicone rubber membranes. (2005) (66)
- Weblabs in Chemical Engineering Education (2007) (65)
- Engineering challenges in cellencapsulation technology (1996) (64)
- Continuous flow membrane plasmapheresis: theoretical models for flux and hemolysis prediction. (1982) (63)
- A constitutive equation for the viscosity of stored red cell suspensions : effect of hematocrit, shear rate, and suspending phase (1991) (61)
- The osmotic pressure of concentrated protein and lipoprotein solutions and its significance to ultrafiltration (1984) (61)
- Size and structure of antigen-antibody complexes. Electron microscopy and light scattering studies. (1988) (61)
- Quantitative assessment of islets of Langerhans encapsulated in alginate. (2011) (60)
- In Situ Electrochemical Oxygen Generation with an Immunoisolation Device (1999) (58)
- Oxygen consumption and diffusion in assemblages of respiring spheres: Performance enhancement of a bioartificial pancreas (2009) (57)
- Topographical mapping of sites of enhanced HRP permeability in the normal rabbit aorta. (1992) (56)
- Number and volume of islets transplanted in immunobarrier devices. (1998) (55)
- Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation (2015) (54)
- Quantitative Analysis of Protein Transport in the Arterial Wall (1981) (50)
- Transport of 125I-albumin across normal and deendothelialized rabbit thoracic aorta in vivo. (1984) (50)
- Electrochemical Glucose Oxidation on a Platinized Platinum Electrode in Krebs‐Ringer Solution II . Potentiostatic Studies (1979) (49)
- Enzymatic regeneration of ATP. I. Alternative routes (1976) (47)
- Permeability of dialyzer membranes to TNF alpha-inducing substances derived from water bacteria. (1992) (47)
- Diffusion of urea in flowing blood (1971) (44)
- Prediction of Marginal Mass Required for Successful Islet Transplantation (2010) (44)
- Effect of coreactants on electrochemical glucose oxidation (1978) (44)
- Mass transfer to a rotating fluid. Part II. Transport from the base of an agitated cylindrical tank (1972) (43)
- Microcinematographic studies of flow patterns in the excised rabbit aorta and its major branches. (1997) (43)
- The effect of weak acids upon the transport of carbon dioxide in alkaline solutions (1977) (43)
- Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply (2018) (42)
- Comments on diffusive and electrostatic effects with immobilized enzymes. (1973) (40)
- NMR Spectroscopy in β Cell Engineering and Islet Transplantation (2001) (38)
- Uremic blood cleansing by diafiltration using a hollow fiber ultrafilter. (1970) (37)
- Hydraulic resistance of red cell beds in an unstirred filtration cell (1989) (36)
- Measurements of the Effective Diffusion Coefficient of Oxygen in Pancreatic Islets (2007) (35)
- MAFA and T3 Drive Maturation of Both Fetal Human Islets and Insulin-Producing Cells Differentiated From hESC. (2015) (34)
- Use of a Physiologic Pharmacokinetic Model of Glucose Homeostasis for Assessment of Performance Requirements for Improved Insulin Therapies (1982) (34)
- A Microperifusion System with Environmental Control for Studying Insulin Secretion by Pancreatic Tissue (1991) (33)
- A hybird artifical pancreas. (1975) (31)
- Electrochemical Glucose Oxidation on a Platinized Platinum Electrode in Krebs‐Ringer Solution III . Effect of Urea (1979) (30)
- Quasi-elastic light scattering of antigen-antibody complexes. (1988) (30)
- Permeability and transport studies in batch and flow dialyzers with applications to hemodialysis. (1969) (29)
- Pyrogen retention by the polyamide membranes. (1992) (29)
- EFFECTS OF THE HYBRID ARTIFICIAL PANCREAS IN DIABETIC RATS (1977) (29)
- Determinants of Fluid and Solute Removal Rates During Hemofiltration (1986) (28)
- Accurate control of oxygen level in cells during culture on silicone rubber membranes with application to stem cell differentiation (2009) (28)
- Engineering microenvironments for embryonic stem cell differentiation to cardiomyocytes. (2009) (27)
- Preparation and magnetic filtration of polyacrylamide gels containing covalently ommobilized proteins and a ferrofluid (1979) (26)
- Scientific basis for assessment of biocompatibility in extracorporeal blood treatment. (1994) (26)
- Low-density lipoprotein transport in blood vessel walls of squirrel monkeys. (1989) (26)
- Oxygen Supply by Photosynthesis to an Implantable Islet Cell Device (2014) (26)
- Theoretical models for transport of low-density lipoproteins in the arterial wall. (1977) (26)
- 6 – Characterization of Islet Preparations (2007) (26)
- Mass transfer to a rotating fluid: Part I. Transport from a stationary disk to a fluid in bödewadt flow (1972) (25)
- NMR spectroscopy in beta cell engineering and islet transplantation. (2001) (25)
- β2-MICROGLOBULIN AND HAEMODIALYSIS (1987) (25)
- Blood cleansing by diafiltration in uremic dog and man. (1971) (24)
- Monoclonal antibodies to bovine serum albumin: affinity and specificity determinations. (1988) (24)
- Steady state diffusion of oxygen in red blood cell and model suspensions (1976) (22)
- Absolute quantitative autoradiography of low concentrations of [125I]-labeled proteins in arterial tissue. (1987) (22)
- Measurement of Glucose Concentration in the Presence of Coreactants with a Platinum Electrode (1982) (22)
- Measurement of flow rates through aortic branches in the anesthetized rabbit. (1997) (22)
- Effect of concentration on partitioning of polystyrene within finely porous glass (1978) (22)
- Size and structure of antigen-antibody complexes: thermodynamic parameters. (1990) (21)
- A web-accessible heat exchanger experiment (2004) (21)
- Electrochemical Glucose Oxidation on a Platinized Platinum Electrode in Krebs‐Ringer Solution IV . Effect of Amino Acids (1981) (20)
- An Implantable Electrochemical Glucose Sensor a (1984) (20)
- Elution Conditions and Degradation Mechanisms in Long‐Term Immunoadsorbent Use (1991) (20)
- Artificial Lungs and Blood–Gas Exchange Devices (1999) (20)
- Perturbations of the endothelium. (1984) (19)
- A red cell deformation model for hemolysis in cross flow membrane plasmapheresis (1984) (19)
- Distribution of glycosaminoglycans in consecutive layers of the rabbit aorta. (1979) (19)
- Synthesis of Tumor Necrosis Factor α and lnterleukin-1 Receptor Antagonist, But Not lnterleukin-1, by Human Mononuclear Cells Is Enhanced by Exposure of Whole Blood to Shear Stress (1996) (18)
- Convective transport in a inst batch dialyzer determination of true membrane permeability from a single measurement mathematics (1968) (18)
- Is the rise in plasma beta-2-microglobulin seen during hemodialysis meaningful? (1989) (18)
- An analysis of carrier facilitated transport in heterogeneous media (1976) (18)
- Substrate inhibition kinetics in assemblages of cells. (1975) (18)
- Design and synthesis of perfluorinated amphiphilic copolymers: Smart nanomicelles for theranostic applications (2011) (18)
- Enumeration of islets by nuclei counting and light microscopic analysis (2010) (16)
- Immunoaffinity removal of xenoreactive antibodies using modified dialysis or microfiltration membranes. (2003) (16)
- Enzymatic regeneration of ATP: II. Equilibrium studies with acetate kinase and adenylate kinase (1977) (16)
- Development of Novel Semipermeable Tubular Membranes for a Hybrid Artificial Pancreas (1980) (15)
- Covalent immobilization of adenylate kinase and acetate kinase in a polyacrylamide gel: enzymes for ATP regeneration. (1976) (15)
- Glucose Isomerase: A Case Study of Enzyme-Catalyzed Process Technology (1974) (14)
- The effect of angiotensin II on in vivo albumin transport in normal rabbit aortic tissue. (1982) (14)
- T3 Induces Both Markers of Maturation and Aging in Pancreatic β-Cells (2018) (13)
- The Filtration of Plasma from Whole Blood: A Novel Approach to Clinical Detoxification (1978) (13)
- Transcellular urea gradients cause minimal depletion of extracellular volume during hemodialysis. (1989) (13)
- Determining molecular weight distributions of antigen–antibody complex by quasi‐elastic light scattering (1991) (12)
- Endothelial Cell Perturbation and Low‐Density Lipoprotein (1987) (12)
- CHAPTER 27 – ENGINEERING CHALLENGES IN IMMUNOISOLATION DEVICE DEVELOPMENT (2000) (11)
- Kinetics of hemodiafiltration. II. Clinical characterization of a new blood cleansing modality. 1975. (1997) (11)
- Enzymatic Regeneration of ATP from AMP and ADP Part I. Thermodynamics, Kinetics, and Process Development (1974) (10)
- Analysis of in vivo deoxygenation of human blood: a feasibility study for an implantable biological fuel cell. (1969) (10)
- Measurement of 125I-low density lipoprotein uptake in selected tissues of the squirrel monkey by quantitative autoradiography. (1988) (10)
- The status of electrochemical sensors for in vivo glucose monitoring. (1977) (10)
- Mechanism of oxygen transport augmentation by hemoglobin. (1973) (9)
- Engineering a bioartificial kidney (1999) (9)
- Quantitation of membrane biocompatibility. (1987) (9)
- Basic Concepts in the Effects of Mass Transfer on Immobilized Enzyme Kinetics (1974) (9)
- Tissue Engineering for Insulin Replacement in Diabetes (2005) (9)
- Evaluation of Hemodialyzers and Dialysis Membranes Report of a Study Group for the Artificial Kidney‐Chronic Uremia Program NIAMDD‐1977 (1978) (8)
- POLYACRYLAMIDE GEL ENTRAPMENT OF ADENYLATE KINASE AND ACETATE KINASE (1979) (8)
- Kinetic Analysis of Receptor‐Mediated Endocytosis and Lysosomal Degradation in Cultured Cells (1984) (8)
- The interleukin hypothesis: a quantitative assessment. (1988) (8)
- The development of an implantable electrochemical glucose sensor: response to glucose in bovine serum ultrafiltrate. (1979) (8)
- Morphological and morphometric characterization of platelet adhesion to the exposed subendothelium of the rabbit thoracic aorta in vivo. (1981) (8)
- Rabbit aortic medial thickness under relaxed and specified simulated in vivo conditions. (1983) (7)
- Enzymatic Regeneration of ATP from AMP and ADP Part II : Enzyme Immobilization and Reactor Development (1974) (7)
- A Study of the Mass Transport Resistance of Glucose Across Rat Capsular Membranes (1987) (7)
- Chapter Twenty-Nine – Engineering Challenges in Immunobarrier Device Development (2007) (6)
- Evaluation of hemodialyzers and dialysis membranes. Report of a study group for the Artificial Kidney-Chronic Uremia Program NIAMDD-1977. Chapter five. Evaluation of toxicity potential of hemodialyzers. (1978) (6)
- Electrophoretic elution and adsorption: Investigations using microporous membrane immunoadsorbents (1991) (6)
- Evaluation of Hemodialyzers and Dialysis Membranes (2008) (5)
- Facilitated diffusion of oxygen in red blood cell suspensions. (1976) (5)
- Analysis of 2,3 diphosphoglycerate-mediated, hemoglobin-facilitated oxygen transport in terms of the Adair reaction mechanism. (1973) (5)
- Membranes in artificial organs: a state-of-the-problem discussion. (1983) (4)
- Perspectives in chemical engineering : research and education (1991) (4)
- Surrogate beta cells (2000) (4)
- Commentary – A hard lesson about transplanting islets into prevascularized devices (2017) (4)
- A Comparison of Web-Based and Laboratory Learning Environments (4)
- A Theoretical Model for Insulin Secretory Dynamics in a Hybrid Artificial Pancreas (1983) (4)
- Membranes for Hemodialysis (1996) (4)
- Staphylococcal protein A adsorption in neoplastic disease: analysis of physicochemical aspects. (1989) (3)
- ENZYMATIC SYNTHESIS OF THE ANTIBIOTIC GRAMICIDIN S: KINETICS OF INHIBITION AND ENZYME DESTABILIZATION (1981) (3)
- Recovery of oil from water with magnetic liquids (1971) (3)
- Technical Foundations of Renal Prostheses (1987) (3)
- 5th Annual Meeting of the International Society of Blood Purification (1987) (3)
- Device for the measurement of small liquid flow rates. (1979) (3)
- SIZE AND STRUCTURE OF ANTIGEN-ANTIBODY COMPLEXES (2005) (3)
- Chapter six: clinical evaluation. Evaluation of hemodialyzers and dialysis membranes. Report of a study group for the Artificial Kidney-Chronic Uremia Program NIAMMDD-1977. (1979) (3)
- Dependence on pH of the hydroxylamine assay for acyl phosphates. (1976) (3)
- Facilitated transport of oxygen in blood in terms of the Adair mechanism and the effect of 2,3-Diphosphoglycerate. (1975) (3)
- Microporous Membrane Filtration for Continuous-Flow Plasmapheresis (1980) (3)
- How To Initiate Dialogue In Student Research Teams (1999) (3)
- Immobilization of Acetate Kinase on Functionalized Solid-Core Polymeric Beads (1978) (3)
- Visual evidence of concentration polarization in cross-flow membrane plasmapheresis. (1987) (2)
- Ultrasonic pulsed Doppler (USPD): A backscatter technique for characterization of particles and nanoparticles; Non-invasive measurement of fluid flow velocity (2010) (2)
- Characterization of cell detachment from hollow fiber affinity membranes. (1999) (2)
- Surrogate beta cells (1997) (2)
- Transmural [125I]albumin concentration in the rabbit aorta during acute hypoxia. (1983) (2)
- Challenges in the Development of Immunoisolation Devices (2014) (2)
- A Model for an Artificial Pancreas: Transient Diffusion in a Two-Phase Composite with a Glucose Concentration-Dependent Insulin Source at the Interface (1980) (2)
- Use of Hydrated Polyphenylene Oxide Sulphonate Ion Exchange Membranes for Artificial Kidneys (1971) (2)
- COMPUTER-AIDED ANALYSIS AND DESIGN OF AN ATP REGENERATION REACTOR (1982) (2)
- Mouse Pluripotent Stem Cell Differentiation Under Physiological Oxygen Reduces Residual Teratomas (2021) (1)
- Extracorporeal removal of immune complexes: Preparation and characterization of immobilized bovine conglutinin (1980) (1)
- Electrocatalytic glucose sensor. (1988) (1)
- Enzymatic Regeneration of ATP from AMP and ADP: Kinetic Studies with the Coupled Enzyme System (1978) (1)
- Functionalized Membranes for Adsorption of Proteins (1992) (1)
- Transplanting allo‐islets without immunosuppression (2014) (1)
- The Rotameter Experiment: A Comparison Of Web Based And Wet Laboratory Learning Environments (2000) (1)
- Crossflow Membrane Filtration (2019) (1)
- ENHANCED OXYGEN SUPPLY TO TISSUE IN PLANAR IMMUNOBARRIER DEVICES BY IN SITU ELECTROCHEMICAL OXYGEN GENERATION (1999) (1)
- Evaluation of hemodialyzers and dialysis membranes. Report of a study for the artificial kidney-chronic uremia program NIAMDD-1977. (1978) (1)
- Estimating number and volume of islets transplanted within a planar immunobarrier diffusion chamber. (1999) (1)
- Number and Volume of Islets Transplanted in Immunobarrier Devices (1998) (1)
- Transport limitations in islets of langerhans culture (2006) (0)
- Subject Index, Vol. 5, 1987 (1987) (0)
- igh-Density Culture of Human Islets on Top of Silicone ubber Membranes (0)
- Measuring viability and functional status of tissues for transplantation (2018) (0)
- THE USE OF CELLULOSE BINDING DOMAIN-PROTEIN A FOR IMMUNOADSORPTION OF IgG (2000) (0)
- Magnetically induced separation of stable emulsions (1972) (0)
- Improving culture of islets of Langerhans: Removing oxygen limitations (2005) (0)
- Current specifications for lot release prior to clinical islet transplantation (2010) (0)
- Contents, Vol. 5, 1987 (1987) (0)
- Systems and methods for separating cannabis-derived compounds using chromatography with liquid or supercritical carbon dioxide (2018) (0)
- Purification of acetate kinase by affinity chromatography. (1978) (0)
- Increasing the quality and shelf-life of pancreatic islets: What we learned from encapsulation studies (2018) (0)
- Biohybrid Artificial Organs (1992) (0)
- Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply (2018) (0)
- Current Opinion in Organ Transplantation: Editorial introductions (2009) (0)
- Evaluation of hemodialyzers and dialysis membranes. Report of a Study Group for the Artificial Kidney-Chronic Uremia Program NIAMDD-1977. Chapter two. In vitro characterization of hemodialyzers. (1977) (0)
- Oxygen supply limitattions in immunoisolated islet of langerhans (1996) (0)
- PART I. THERMODYNAMICS, KINETICS, AND PROCESS DEVELOPMENT (1974) (0)
- Protein purification process engineeering. Crossflow membrane filtration. (1994) (0)
- In vitro and in vivo testing of an electrocatalytic glucose sensor. (1990) (0)
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