Claude Klee

Q: What Schools Are Affiliated With Claude Klee

Claude Klee is affiliated with the following schools: Université Paris Cité, University of Bordeaux, Baylor College of Medicine, Aix-Marseille University, Karolinska Institute

Claude Klee's AcademicInfluence.com Rankings

Claude Klee

Biology

#8977

World Rank

#12126

Historical Rank

Biochemistry

#1368

World Rank

#1490

Historical Rank

biology Degrees

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Biology

Claude Klee's Degrees

Bachelors Biochemistry Université Paris Cité
Masters Biochemistry Université Paris Cité

Why Is Claude Klee Influential?

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According to Wikipedia, Claude Klee was a French biochemist. Biography Claude B. Klee attended the University of Marseille until she graduated with her medical degree in 1959. She moved to the United States to work at the National Institute of Mental Health and also spent some time in Basel. In 1961 Klee began to work at the National Institutes of Health with Herbert Tabor, Louis Sokoloff and Maxine Singer. By 1966 Klee had a laboratory at the National Institute of Arthritis and Metabolic Diseases. In 1974 she started what was to become her iconic work at the National Cancer Institute's Biochemistry Laboratory which led to the 1991 Presidential Rank Awards. Klee was elected to the National Academy of Medicine in 1992. She also won the FASEB Excellence in Science Award. From 1995 Klee was a member of the American Academy of Arts and Sciences. Klee was also awarded the Women in Science and Engineering Lifetime Achievement Award. She died in 2017 in Maryland, US.

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Claude Klee's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Solution structure of a calmodulin-target peptide complex by multidimensional NMR. (1994) (1137)
Regulation of the Calmodulin-stimulated Protein Phosphatase, Calcineurin* (1998) (908)
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. (1992) (747)
Calcineurin: a calcium- and calmodulin-binding protein of the nervous system. (1979) (625)
Solution structure of calcium-free calmodulin (1995) (617)
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. (1992) (541)
Discovery of A Ca2+‐and calmodulin‐dependent protein phosphatase (1982) (403)
Purification and characterization of smooth muscle myosin light chain kinase. (1981) (369)
Conformational transition accompanying the binding of Ca2+ to the protein activator of 3',5'-cyclic adenosine monophosphate phosphodiesterase. (1977) (340)
Phosphorylation of smooth muscle myosin light chain kinase by the catalytic subunit of adenosine 3': 5'-monophosphate-dependent protein kinase. (1978) (334)
Advances in second messenger and phosphoprotein research (1988) (330)
Ca2+-dependent phospholipid- (and membrane-) binding proteins. (1988) (323)
Solution structure of Ca2+–calmodulin reveals flexible hand-like properties of its domains (2001) (323)
Positive cooperative binding of calcium to bovine brain calmodulin. (1980) (299)
Calcineurin: from structure to function. (2000) (294)
Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B. (1994) (292)
Effects of cations on affinity of calmodulin for calcium: ordered binding of calcium ions allows the specific activation of calmodulin-stimulated enzymes. (1981) (277)
Superoxide dismutase protects calcineurin from inactivation (1996) (264)
Identification of the NH2‐terminal blocking group of calcineurin B as myristic acid (1982) (237)
Calcium as a cellular regulator (1999) (234)
Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. (1992) (207)
Identification, characterization, and functional correlation of calmodulin-dependent protein phosphatase in sperm (1988) (190)
Ca2+ binding and conformational change in two series of point mutations to the individual Ca(2+)-binding sites of calmodulin. (1992) (188)
Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells. (1992) (185)
Functional domain structure of calcineurin A: mapping by limited proteolysis. (1989) (172)
Renaming the DSCR1 / Adapt78 gene family as RCAN: regulators of calcineurin (2007) (163)
Agonist and antagonist properties of calmodulin fragments. (1984) (147)
Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain. (1989) (145)
Activation of calcineurin by limited proteolysis. (1983) (138)
Calmodulin activates the isolated catalytic unit of brain adenylate cyclase. (1981) (130)
The structure of the B subunit of calcineurin. (1984) (129)
Changes in D(--)-beta-hydroxybutyric dehydrogenase activity during brain maturation in the rat. (1967) (119)
Isolation and characterization of bovine brain calcineurin: a calmodulin-stimulated protein phosphatase. (1983) (103)
Subunit structure and catalytic properties of bovine brain Ca2+-dependent cyclic nucleotide phosphodiesterase. (1979) (98)
Interaction of calmodulin with myosin light chain kinase and cAMP-dependent protein kinase in bovine brain. (1981) (97)
Low affinity Ca2+-binding sites of calcineurin B mediate conformational changes in calcineurin A. (2000) (96)
Exocytosis induction in Paramecium tetraurelia cells by exogenous phosphoprotein phosphatase in vivo and in vitro: possible involvement of calcineurin in exocytotic membrane fusion (1987) (91)
Calcium modulation of inositol 1,4,5-trisphosphate-induced calcium release from neuroblastoma x glioma hybrid (NG108-15) microsomes. (1986) (90)
Isotope-edited multidimensional NMR of calcineurin B in the presence of the non-deuterated detergent CHAPS (1993) (87)
Phosphorylase kinase from rabbit skeletal muscle: identification of the calmodulin-binding subunits. (1980) (82)
Purification of cyclic 3',5'-nucleotide phosphodiesterase inhibitory protein by affinity chromatography on activator protein coupled to Sepharose. (1978) (79)
Dephosphorylation of phosphopeptides by calcineurin (protein phosphatase 2B). (1994) (78)
The effects of deletions in the central helix of calmodulin on enzyme activation and peptide binding. (1989) (73)
Serine/threonine phosphatases in the nervous system (1991) (72)
Calmodulin binding by calcineurin. Ligand-induced renaturation of protein immobilized on nitrocellulose. (1987) (69)
Genetically engineered calmodulins differentially activate target enzymes. (1986) (68)
Activation of phosphorylase kinase from rabbit skeletal muscle by calmodulin and troponin (1979) (65)
Conformation-dependent nitration of the protein activator of cyclic adenosine 3',5'-monophosphate phosphodiesterase. (1978) (64)
The processive degradation of individual polyribonucleotide chains. II. Micrococcus lysodeikticus polynucleotide phosphorylase. (1968) (64)
CONCERTED ROLE OF CALMODULIN AND CALCINEURIN IN CALCIUM REGULATION (1980) (63)
Solution structure of calmodulin and its complex with a myosin light chain kinase fragment. (1992) (63)
Ultrastructural immunocytochemical localization of calmodulin in cultured cells. (1983) (62)
Concerted regulation of protein phosphorylation and dephosphorylation by calmodulin (1991) (53)
Calcium Dependence of the Interaction between Calmodulin and Anthrax Edema Factor* (2003) (52)
Interaction of 125I-labeled Ca2+-dependent regulator protein with cyclic nucleotide phosphodiesterase and its inhibitory protein. (1978) (52)
Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21-->q22 and 2p16-->p15 respectively. (1996) (50)
Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase. (1989) (49)
Molecular cloning and characterization of the genes encoding the two subunits of Drosophila melanogaster calcineurin. (1992) (47)
Calcium ion dependent covalent modification of calmodulin with norchlorpromazine isothiocyanate. (1983) (46)
The role of α-lactalbumin in lactose synthetase (1970) (46)
1H, 13C, 15N nuclear magnetic resonance backbone assignments and secondary structure of human calcineurin B. (1994) (45)
Specific perturbation by Ca2+ of tyrosyl residue 138 of calmodulin. (1979) (45)
Heteronuclear 3D NMR and isotopic labeling of calmodulin. Towards the complete assignment of the 1H NMR spectrum. (1990) (44)
The interaction of -lactalbumin and the A protein of lactose synthetase. (1972) (43)
Characterization of the lanthanide ion-binding properties of calcineurin-B using laser-induced luminescence spectroscopy. (1994) (41)
[27] Purification of smooth muscle myosin light-chain kinase (1982) (40)
Selective effects of CAPP1-calmodulin on its target proteins. (1985) (37)
The regulation of muscle phosphorylase kinase by calcium ions, calmodulin and troponin-C. (1981) (34)
CALCIUM CONTROL OF MUSCLE PHOSPHORYLASE KINASE THROUGH THE COMBINED ACTION OF CALMODULIN AND TROPONIN * (1980) (34)
CAPP‐calmodulin: A potent competitive inhibitor of calmodulin actions (1984) (33)
There is communication between all four Ca(2+)-bindings sites of calcineurin B. (2001) (30)
Amino acid incorporation into proteolipid of myelin in vitro. (1965) (29)
Reversible polymerization of histidine ammonia lyase. The role of sulfhydryl groups in the activity and polymeric state of the enzyme. (1970) (28)
Rabbit FKBP-59/HBI does not inhibit calcineurin activity in vitro. (1994) (27)
Histidine ammonia-lyase. The use of 4-fluorohistidine in identification of the rate-determining step. (1975) (27)
Calcineurin: A calcium- andcalmodulin-bindi ng protein ofthe nervous system (cyclic nucleotide phosphodiesterase/neurotransmitters) (1979) (26)
Chapter 4 – Calmodulin: Structure—Function Relationships (1980) (26)
Metal activation of histidine ammonia-lyase. Metal ion-sulfhydryl group relationship. (1972) (26)
Calcium-induced sensitization of the central helix of calmodulin to proteolysis. (1991) (24)
Regulation of the calcium signal by calmodulin. (1986) (24)
Selective affinity chromatography with calmodulin fragments coupled to sepharose. (1985) (24)
Regulation of calcineurin by oxidative stress. (2003) (24)
Purification of smooth muscle myosin light-chain kinase. (1982) (24)
The effect of oncomodulin on cAMP phosphodiesterase activity. (1984) (23)
Reversible and irreversible activation of cyclic nucleotide phosphodiesterase: separation of the regulatory and catalytic domains by limited proteolysis. (1984) (22)
A convenient method for the preparation of primer-dependent polynucleotide phosphorylase from Micrococcus lysodeikticus. (1967) (22)
Spurious protein activators of Bordetella pertussis adenylate cyclase. (2005) (22)
Large scale preparation of calmodulin. (1988) (21)
Chinese hamster ovary cell population density affects intracellular concentrations of calcium-dependent regulator and ability of regulator to inhibit adenylate cyclase activity. (1979) (21)
The proteolytic conversion of polynucleotide phosphorylase to a primer-dependent form. (1969) (20)
Affinity selection of chemically modified proteins: role of lysyl residues in the binding of calmodulin to calcineurin. (1987) (20)
Purification and characterization of a novel Ca2+-binding protein (CBP-18) from bovine brain. (1984) (19)
Stereospecific irreversible inhibition of histidine ammonia-lyase by L-cysteine. (1974) (18)
4-Nitro-L-histidine as a substrate for histidine ammonia-lyase: the role of beta-hydrogen acidity in the rate-limiting step. (1979) (14)
Keeping up with calcium: conference on calcium-binding proteins and calcium function in health and disease. (2002) (13)
Activation of Bordetella pertussis adenylate cyclase by the carboxyl-terminal tryptic fragment of calmodulin. (1986) (12)
Calcineurin: A Member of a Family of Calmodulin-Stimulated Protein Phosphatases (1984) (12)
Comparative study of different preparations of yeast soluble ribonucleic acid. (1962) (12)
Isolation of a cysteine-peptide at the active site of histidine ammonia-lyase. (1972) (12)
THYROXINE STIMULATION OF AMINO ACID INCORPORATION INTO RIBOSOMAL PROTEIN. (1963) (12)
Structural Alterations of Polynucleotide Phosphorylase Leading to Primer Dependence (1967) (11)
Characterization of polynucleotide phosphorylase from Micrococcus luteus and isolation of the 13,000 base poly(A) product of the polymerization reaction. (1982) (10)
Multiple forms of calcineurin, a brain isozyme of the calmodulin-stimulated protein phosphatase. (1990) (10)
Chapter 8 – Smooth Muscle Myosin Light Chain Kinase (1980) (10)
Phenothiazine-binding and attachment sites of CAPP1-calmodulin. (1989) (10)
Characterization of a high-affinity monoclonal antibody to calcineurin whose epitope defines a new structural domain of calcineurin A. (1989) (9)
Study of calcineurin structure by limited proteolysis. (2002) (9)
2-fluorourocanic acid, a potent reversible inhibitor of urocanase. (1977) (8)
Purification and Characterization of Smooth Muscle Myosin Light (1981) (8)
Overexpressed mutant G93A superoxide dismutase protects calcineurin from inactivation. (2004) (7)
The effect of thyroid on protein synthesis in brain and other organs. (1966) (7)
Purification and peptide mapping of calmodulin and its chemically modified derivatives by reversed-phase high-performance liquid chromatography. (1985) (6)
Calmodulin: the Coupling Factor of the Two Second Messengers Ca2+ and cAMP (1979) (6)
Calcineurin, a Calmodulin-Stimulated Protein Phosphatase (1985) (5)
Polynucleotide phosphorylase of Micrococcus luteus (Micrococcus lysodeikticus). The effect of sulfhydryl compounds on the ability to catalyze the polymerization reaction. (1968) (5)
A deoxyadenylate kinase activity associated with polynucleotide phosphorylase from Micrococcus luteus. (1976) (5)
VERSATILITY OF CALMODULIN AS A CYTOSOLIC REGULATOR OF CELLULAR FUNCTION (1983) (5)
The origin of the electrophoretic microheterogeneity in primer-independent polynucleotide phosphorylase from Micrococcus luteus. (1978) (5)
Purification of calmodulin-stimulated phosphodiesterase by affinity chromatography on calmodulin fragment 1-77 linked to sepharose. (1988) (4)
[33]Synthesis and properties of CAPP1-calmodulin (1987) (3)
The phosphorylation of calmodulin and calmodulin fragments by kinase fractions from bovine brain. (1988) (3)
The role of alpha-lactalbumin in lactose synthetase. (1970) (3)
Calcium Modulation of Inositol 1 , 4 , 5-Trisphosphate-induced Calcium Release from Neuroblastoma X Glioma Hybrid ( NG 108-15 ) (3)
Electrostatic repulsion between molecules of like charge can be misinterpreted as binding (1990) (3)
Chapter 90 – Calcineurin (2010) (3)
Isolation and Characterization of Intracellular Ca2 + -Binding Proteins by High Performance Liquid Chromatography (1983) (2)
CALCIUM-FREE CALMODULIN (1995) (2)
[149b] Histidine ammonia-lyase (Pseudomonas) (1971) (2)
Interaction of Calmodulin with cAMP Dependent Protein Kinase in Brain (1982) (1)
Identification of a calmodulin-binding subunit on phosphorylase kinase [proceedings]. (1980) (1)
THE DOMAIN STRUCTURE OF CALCINEURIN (1987) (1)
Evidence for a GTP-dependent increase in membrane permeability for calcium in NG108-15 microsomes. (1989) (1)
Synthesis and properties of CAPP1-calmodulin. (1987) (0)
Malcolm Daniel Lane (2014) (0)
CALMODULIN MODULATED PROTEIN PHOSPHORYLATION (1983) (0)
Proceedings of the International Conference on Cyclic Nucleotides, Calcium and Protein Phosphorylation (6th) Held in Bethesda, Maryland on September 2-7, 1986. Advances in Second Messenger and Phosphorprotein Research. Volume 21A. Abstracts Volume (1988) (0)
Polynucleotide Phosphorylase of Micrococcus Zuteus ( Micrococcus lysodeikticus ) (2003) (0)
CHAPTER 106 – Calcineurin (2003) (0)
Flexibility of the calmodulin central helix is key to its function. (1993) (0)
Conference on calcium-binding proteins and calcium function in health and disease (2002) (0)
Nuclear Magnetic Resonance Backbone Assignments and Secondary Structure of Human Calcineurin BT (2001) (0)
A tribute to Dr. Setsuro Ebashi. (2008) (0)
Composition and Synthesis of Gangliosides in Rat Hepatocyte and (2003) (0)
Activation of calcineurin by limited proteolysis ( calmodulin / Ca 2 + / protein phosphatase ) (0)
Structure of Calcineurin and Its Complex with Immunophilins (2000) (0)
Cellular regulation sketched on a large canvass: Calcium and cAMP as Synarchic Messengers by Howard Rasmussen, John Wiley and Sons, 1981. £29.25 (xiv + 370 pages) ISBN 0 471 08396 8 (1983) (0)
PROTEIN BIOSYNTHESIS IN THE DEVELOPING BRAIN (1966) (0)
CALMODULIN MEDIATED REGULATION OF CYTOSOLIC CALCIUM (1981) (0)
Solution structure of Calcium calmodulin C-terminal domain (2001) (0)
For love of metals. (2015) (0)
Special section on calcineurin (2003) (0)
Amino Acid Incorporation into Myelin in Cell-Free Rat Brain Preparations. (1964) (0)

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What Schools Are Affiliated With Claude Klee?

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