Claude Leclerc

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Claude Leclerc is affiliated with the following schools: University of Cape Town, Université Paris Cité, Charles University, University of Melbourne

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Claude Leclerc

Computer Science

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Algorithms

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#423

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Machine Learning

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Computer Science

Claude Leclerc's Degrees

PhD Computer Science Université Paris Cité

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Claude Leclerc's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Neonatal adaptive immunity comes of age (2004) (960)
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis (2003) (652)
Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils. (2009) (326)
Dissection of ESAT-6 System 1 of Mycobacterium tuberculosis and Impact on Immunogenicity and Virulence (2006) (306)
The Adenylate Cyclase Toxin of Bordetella pertussis Binds to Target Cells via the αMβ2 Integrin (Cd11b/Cd18) (2001) (290)
Carrier-induced epitopic suppression, a major issue for future synthetic vaccines. (1985) (280)
Control of M. tuberculosis ESAT-6 Secretion and Specific T Cell Recognition by PhoP (2008) (263)
Dendritic Cells Are Host Cells for Mycobacteria In Vivo That Trigger Innate and Acquired Immunity1 (2002) (244)
Reduced Response to Multiple Vaccines Sharing Common Protein Epitopes That Are Administered Simultaneously to Infants (1998) (239)
Upon TLR9 signaling, CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs. (2005) (219)
Genome analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of the etiologic agent of tuberculosis (2013) (206)
Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation. (2008) (192)
Molecular detection and in vivo analysis of the specific T cell response to a protein antigen (1992) (188)
Comparison of immune responses of mice immunized with five different Mycobacterium bovis BCG vaccine strains (1996) (183)
Disruption of the ESX‐5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation (2012) (179)
Recombinant parvovirus-like particles as an antigen carrier: a novel nonreplicative exogenous antigen to elicit protective antiviral cytotoxic T cells. (1997) (175)
Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell responses in vivo after viral stimulation. (2004) (160)
In vivo induction of cytotoxic T cell response by a free synthetic peptide requires CD4+ T cell help. (1991) (156)
Type I interferons protect neonates from acute inflammation through interleukin 10–producing B cells (2007) (148)
Antigenicity and immunogenicity of the HIV-1 gp41 epitope ELDKWA inserted into permissive sites of the MalE protein. (2000) (146)
Functional Analysis of Early Secreted Antigenic Target-6, the Dominant T-cell Antigen of Mycobacterium tuberculosis, Reveals Key Residues Involved in Secretion, Complex Formation, Virulence, and Immunogenicity* (2005) (145)
Influence of ESAT-6 Secretion System 1 (RD1) of Mycobacterium tuberculosis on the Interaction between Mycobacteria and the Host Immune System1 (2005) (136)
Insect Baculoviruses Strongly Potentiate Adaptive Immune Responses by Inducing Type I IFN1 (2007) (130)
CD8α2 CD11b+ Dendritic Cells Present Exogenous Virus-like Particles to CD8+ T Cells and Subsequently Express CD8α and CD205 Molecules (2002) (128)
A Fully Synthetic Therapeutic Vaccine Candidate Targeting Carcinoma-Associated Tn Carbohydrate Antigen Induces Tumor-Specific Antibodies in Nonhuman Primates (2004) (128)
New tools for antigen delivery to the MHC class I pathway. (2004) (122)
Interaction of Bordetella pertussis Adenylate Cyclase with CD11b/CD18 (2003) (117)
Carrier-induced epitopic suppression is initiated through clonal dominance. (1989) (117)
In Vivo, Dendritic Cells Can Cross-Present Virus-Like Particles Using an Endosome-to-Cytosol Pathway 1 (2003) (115)
An Increase in Antimycobacterial Th1-Cell Responses by Prime-Boost Protocols of Immunization Does Not Enhance Protection against Tuberculosis (2006) (113)
Eradication of large tumors in mice by a tritherapy targeting the innate, adaptive, and regulatory components of the immune system. (2007) (113)
In Vivo Induction of a High-Avidity, High-Frequency Cytotoxic T-Lymphocyte Response Is Associated with Antiviral Protective Immunity (2000) (110)
Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential. (2012) (108)
The Extra Domain A from Fibronectin Targets Antigens to TLR4-Expressing Cells and Induces Cytotoxic T Cell Responses In Vivo1 (2007) (106)
In vivo induction of CTL responses by recombinant adenylate cyclase of Bordetella pertussis carrying viral CD8+ T cell epitopes. (1996) (106)
CD4 T Cells with Effector Memory Phenotype and Function Develop in the Sterile Environment of the Fetus (2014) (106)
Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein. (2005) (103)
Anti-Tumor Immunity Provided by a Synthetic Multiple Antigenic Glycopeptide Displaying a Tri-Tn Glycotope1 (2001) (102)
Delivery of CD8+ T-Cell Epitopes into Major Histocompatibility Complex Class I Antigen Presentation Pathway by Bordetella pertussis Adenylate Cyclase: Delineation of Cell Invasive Structures and Permissive Insertion Sites (2000) (101)
Anti-viral protection conferred by recombinant adenylate cyclase toxins from Bordetella pertussis carrying a CD8+ T cell epitope from lymphocytic choriomeningitis virus. (1997) (100)
Ontogeny and innate properties of neonatal dendritic cells. (2003) (98)
Chemoselective assembly and immunological evaluation of multiepitopic glycoconjugates bearing clustered Tn antigen as synthetic anticancer vaccines. (2005) (97)
The preferential induction of a Th1 immune response by DNA-based immunization is mediated by the immunostimulatory effect of plasmid DNA. (1997) (95)
High Frequency of CD4+ T Cells Specific for the TB10.4 Protein Correlates with Protection against Mycobacterium tuberculosis Infection (2006) (94)
Expression of heterologous genes in Mycobacterium bovis BCG: induction of a cellular response against HIV-1 Nef protein. (1991) (94)
The macrophage, target cell of the synthetic adjuvant muramyl dipeptide (1978) (93)
A synthetic vaccine constructed by copolymerization of B and T cell determinants (1987) (92)
Therapy of murine tumors with recombinant Bordetella pertussis adenylate cyclase carrying a cytotoxic T cell epitope. (1999) (91)
Cell Envelope Protein PPE68 Contributes to Mycobacterium tuberculosis RD1 Immunogenicity Independently of a 10-Kilodalton Culture Filtrate Protein and ESAT-6 (2004) (91)
Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens. (2004) (86)
Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells (2018) (83)
Charge-dependent translocation of Bordetella pertussis adenylate cyclase toxin into eukaryotic cells: implication for the in vivo delivery of CD8(+) T cell epitopes into antigen-presenting cells. (1998) (81)
Decoration of Outer Membrane Vesicles with Multiple Antigens by Using an Autotransporter Approach (2014) (81)
Expression of Escherichia coliβ‐galactosidase in Mycobacterium bovis BCG using an expression system isolated from Mycobacterium paratuberculosis which induced humoral and cellular immune responses (1992) (81)
Effect of Attenuation of Treg during BCG Immunization on Anti-Mycobacterial Th1 Responses and Protection against Mycobacterium tuberculosis (2008) (81)
Identification of a T-cell epitope adjacent to neutralization antigenic site 1 of poliovirus type 1 (1991) (80)
Antigen Targeting to CD11b Allows Efficient Presentation of CD4+ and CD8+ T Cell Epitopes and In Vivo Th1-Polarized T Cell Priming1 (2004) (79)
MGL signaling augments TLR2‐mediated responses for enhanced IL‐10 and TNF‐α secretion (2013) (78)
Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis (2020) (77)
A fully synthetic immunogen carrying a carcinoma-associated carbohydrate for active specific immunotherapy. (1999) (77)
In vivo treatment with recombinant IL‐12 protects C57BL/6J mice against secondary alveolar echinococcosis (1998) (77)
Characterization of T‐cell immune responses of Echinococcus multilocularis‐infected C57BL/6J mice (1996) (76)
Oral immunization with recombinant BCG induces cellular and humoral immune responses against the foreign antigen. (1993) (76)
ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis. (2011) (74)
TLR3 ligand stimulates fully functional memory CD8+ T cells in the absence of CD4+ T-cell help. (2007) (73)
Virus-like particles: a new family of delivery systems (2002) (73)
The T-cell receptor repertoire of tumor-infiltrating regulatory T lymphocytes is skewed toward public sequences. (2012) (73)
The B subunit of Shiga toxin coupled to full-size antigenic protein elicits humoral and cell-mediated immune responses associated with a Th1-dominant polarization. (2003) (72)
Direct delivery of the Bordetella pertussis adenylate cyclase toxin to the MHC class I antigen presentation pathway. (1999) (71)
Acylation of lysine 860 allows tight binding and cytotoxicity of Bordetella adenylate cyclase on CD11b-expressing cells. (2005) (70)
Efficient In Vivo Priming of Specific Cytotoxic T Cell Responses by Neonatal Dendritic Cells1 (2002) (68)
Preparation of a multiple antigen glycopeptide (MAG) carrying the Tn antigen. A possible approach to a synthetic carbohydrate vaccine. (2009) (67)
Intranasal Delivery of Recombinant Parvovirus-Like Particles Elicits Cytotoxic T-Cell and Neutralizing Antibody Responses (1999) (65)
Delivery of Multiple Epitopes by Recombinant Detoxified Adenylate Cyclase of Bordetella pertussisInduces Protective Antiviral Immunity (2001) (64)
Expression of heterologous peptides at two permissive sites of the MalE protein: antigenicity and immunogenicity of foreign B-cell and T-cell epitopes. (1992) (63)
A recombinant virus‐like particle system derived from parvovirus as an efficient antigen carrier to elicit a polarized Th1 immune response without adjuvant (1998) (62)
Intranasal immunization of mice against influenza with synthetic peptides anchored to proteosomes. (1995) (61)
Recombinant BCG strains expressing the SIVmac251nef gene induce proliferative and CTL responses against nef synthetic peptides in mice. (1995) (58)
Oral macrophage-like cells play a key role in tolerance induction following sublingual immunotherapy of asthmatic mice (2011) (58)
In vivo receptor‐mediated delivery of a recombinant invasive bacterial toxoid to CD11c+CD8α–CD11bhigh dendritic cells (2002) (55)
The cellular location of a foreign B cell epitope expressed by recombinant bacteria determines its T cell-independent or T cell-dependent characteristics. (1991) (55)
CD8+-T-CellResponses of Mycobacterium-Infected Mice to a Newly Identified MajorHistocompatibility Complex Class I-Restricted Epitope Shared byProteins of the ESAT-6Family (2003) (54)
Fetal spleen stroma drives macrophage commitment (2006) (53)
Adenylate cyclase toxin translocates across target cell membrane without forming a pore (2010) (52)
Systemic infection of Leishmania tropica (major) in various strains of mice. (1981) (51)
Protection against tuberculosis induced by oral prime with Mycobacterium bovis BCG and intranasal subunit boost based on the vaccine candidate Ag85B-ESAT-6 does not correlate with circulating IFN-gamma producing T-cells. (2009) (51)
New approaches in vaccine development. (1998) (51)
DNA‐Mediated Immunization to the Hepatitis B Surface Antigen (1995) (51)
Rapamycin Impairs Antitumor CD8+ T-cell Responses and Vaccine-Induced Tumor Eradication. (2015) (50)
Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN (2007) (49)
In vivo regulation of humoral and cellular immune responses of mice by a synthetic adjuvant, N-acetyl-muramyl-L-alanyl-D-isoglutamine, muramyl dipeptide for MDP. (1979) (49)
Cell-invasive activity of epitope-tagged adenylate cyclase of Bordetella pertussis allows in vitro presentation of a foreign epitope to CD8+ cytotoxic T cells (1995) (49)
The in vivo elimination of CD4+ T cells prevents the induction but not the expression of carrier-induced epitopic suppression. (1990) (49)
Calcium Influx Rescues Adenylate Cyclase-Hemolysin from Rapid Cell Membrane Removal and Enables Phagocyte Permeabilization by Toxin Pores (2012) (48)
CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection (2016) (47)
In vivo T helper cell response to retro-inverso peptidomimetics. (1997) (47)
Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant. (2010) (47)
Induction of a Polarized Th1 Response by Insertion of Multiple Copies of a Viral T-Cell Epitope into Adenylate Cyclase of Bordetella pertussis (2000) (46)
Induction of virus-neutralizing antibodies by bacteria expressing the C3 poliovirus epitope in the periplasm. The route of immunization influences the isotypic distribution and the biologic activity of the antipoliovirus antibodies. (1990) (46)
Regulatory B and T cells in infections. (2008) (46)
Induction of carbohydrate-specific antibodies in HLA-DR transgenic mice by a synthetic glycopeptide: a potential anti cancer vaccine for human use. (2003) (45)
Antibody response to a foreign epitope expressed at the surface of recombinant bacteria: importance of the route of immunization. (1989) (45)
Epitopic suppression in synthetic vaccine models: analysis of the effector mechanisms. (1987) (45)
Engineering parvovirus-like particles for the induction of B-cell, CD4(+) and CTL responses. (1999) (43)
Immunogenicity of poliovirus B and T cell epitopes presented by hybrid porcine parvovirus particles. (1995) (43)
Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin (2012) (42)
In vivo induction of CD4+ T cell responses by antigens covalently linked to synthetic microspheres does not require adjuvant. (1995) (42)
Dectin-1 activation unlocks IL12A expression and reveals the TH1 potency of neonatal dendritic cells. (2015) (42)
Lack of Th1 or Th2 polarization of CD4+ T cell response induced by particulate antigen targeted to phagocytic cells. (1997) (41)
Induction of Neutralizing Antibodies and Th1-Polarized and CD4-Independent CD8+ T-Cell Responses following Delivery of Human Immunodeficiency Virus Type 1 Tat Protein by Recombinant Adenylate Cyclase of Bordetella pertussis (2005) (41)
Carbohydrate antigens: synthesis aspects and immunological applications in cancer. (2006) (41)
Pivotal role of plasmacytoid dendritic cells in inflammation and NK-cell responses after TLR9 triggering in mice. (2012) (41)
Tn Glycosylation of the MUC6 Protein Modulates Its Immunogenicity and Promotes the Induction of Th17-biased T Cell Responses* (2010) (41)
Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis (2017) (40)
A Genetic System to Elicit and Monitor Anti-Peptide Antibodies Without Peptide Synthesis (1991) (39)
Associations between consumption of dietary fibers and the risk of cardiovascular diseases, cancers, type 2 diabetes, and mortality in the prospective NutriNet-Santé cohort. (2020) (39)
Immune responses induced by recombinant BCG strains according to level of production of a foreign antigen: malE. (2000) (38)
Interleukin 2 increases protection against experimental rabies. (1988) (38)
Expression and immunogenicity of the V3 loop from the envelope of human immunodeficiency virus type 1 in an attenuated aroA strain of Salmonella typhimurium upon genetic coupling to two Escherichia coli carrier proteins. (1993) (37)
Inhibition of human IL 2 production by MDP and derivatives. (1984) (37)
Secondary Echinococcus multilocularis infection in A/J mice: delayed metacestode development is associated with Th1 cytokine production (1997) (36)
Induction of CTL and Nonpolarized Th Cell Responses by CD8α+ and CD8α− Dendritic Cells1 (2001) (36)
The rate of dissociation between antibody and antigen determines the efficiency of antibody-mediated antigen presentation to T cells. (1998) (36)
Delivery of a MalE CD4+-T-Cell Epitope into the Major Histocompatibility Complex Class II Antigen Presentation Pathway by Bordetella pertussis Adenylate Cyclase (2002) (36)
Tumor-Derived TGFβ Alters the Ability of Plasmacytoid Dendritic Cells to Respond to Innate Immune Signaling. (2018) (35)
Mycobacterium bovis BCG priming induces a strong potentiation of the antibody response induced by recombinant BCG expressing a foreign antigen (1994) (35)
Genetic control of antibody responses induced against an antigen delivered by recombinant attenuated Salmonella typhimurium (1994) (35)
Immunogenicity of foreign peptide epitopes expressed in bacterial envelope proteins. (1990) (35)
Recombinant adenylate cyclase toxin of Bordetella pertussis induces cytotoxic T lymphocyte responses against HLA*0201-restricted melanoma epitopes. (2003) (35)
Influence of MDP and of some analogous synthetic glycopeptides on the in vitro mouse spleen cell viability and immune response to sheep erythrocytes. (1978) (35)
Intracytoplasmic delivery of listeriolysin O by a vaccinal strain of Bacillus anthracis induces CD8-mediated protection against Listeria monocytogenes. (1997) (34)
Monoclonal antibodies toward different Tn-amino acid backbones display distinct recognition patterns on human cancer cells. Implications for effective immuno-targeting of cancer (2013) (34)
The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR. (2015) (34)
Antigen Targeting to CD11b+ Dendritic Cells in Association with TLR4/TRIF Signaling Promotes Strong CD8+ T Cell Responses (2014) (33)
Neonatal Plasmacytoid Dendritic Cells (pDCs) Display Subset Variation but Can Elicit Potent Anti-Viral Innate Responses (2013) (33)
B cells promote tumor progression in a mouse model of HPV‐mediated cervical cancer (2016) (32)
Synthesis and immunological evaluation of an antitumor neoglycopeptide vaccine bearing a novel homoserine Tn antigen. (2004) (32)
The adenylate cyclase toxin from Bordetella pertussis--a novel promising vehicle for antigen delivery to dendritic cells. (2004) (32)
Induction of cytotoxic T‐cell response by optimal‐length peptides does not require CD4+ T‐cell help (1996) (31)
The Shift of Th1 to Th2 Immunodominance Associated with the Chronicity of Mycobacterium bovis Bacille Calmette-Guérin Infection Does Not Affect the Memory Response 1 (2003) (31)
Processing of the Bovine Spongiform Encephalopathy-Specific Prion Protein by Dendritic Cells (2006) (31)
Demonstration of muramyl dipeptide (MDP)‐induced T suppressor cells responsible for MDP immunosuppressive activity (1982) (30)
Short synthetic glycopeptides successfully induce antibody responses to carcinoma-associated Tn antigen. (2000) (30)
Enhancement by murabutide of the immune response to natural and synthetic hepatitis B surface antigens (1984) (30)
Synthetic immunomodulators and synthetic vaccines. (1986) (30)
The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells. (2009) (29)
Identification of helper T cell epitopes of dengue virus E-protein. (1993) (29)
Induction of protective antiviral cytotoxic T cells by a tubular structure capable of carrying large foreign sequences. (2002) (28)
Purification and properties of a β-1,6-glucanase from Streptomyces sp. EF-14, an actinomycete antagonistic to Phytophthora spp. (2001) (27)
Suppression of murine lupus autoantibodies to DNA by administration of muramyl dipeptide and syngeneic anti-DNA IgG. (1985) (27)
Influence of a synthetic adjuvant (MDP) on qualitative and quantitative changes of serum globulins. (1978) (27)
Influence of flanking sequences on presentation efficiency of a CD8+ cytotoxic T-cell epitope delivered by parvovirus-like particles. (2004) (27)
Extending the CD4+ T-Cell Epitope Specificity of the Th1 Immune Response to an Antigen Using aSalmonella enterica Serovar Typhimurium Delivery Vehicle (2000) (26)
Inhibitory and stimulatory effects of a synthetic glycopeptide (MDP) on the in vitro PFC response: factors affecting the response. (1979) (26)
Induction of T cell responses by chimeric bacterial proteins expressing several copies of a viral T cell epitope (1993) (26)
Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8+ T Cell Responses. (2019) (26)
Plasmacytoid dendritic cells engagement by influenza vaccine as a surrogate strategy for driving T-helper type 1 responses in human neonatal settings. (2014) (26)
Delivery of the HIV-1 Tat protein to dendritic cells by the CyaA vector induces specific Th1 responses and high affinity neutralizing antibodies in non human primates. (2006) (25)
Stimulation of a memory B cell response does not require primed helper T cells (1995) (25)
Modulation of carrier-induced epitopic suppression by Bordetella pertussis components and muramyl peptide. (1987) (25)
Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination. (2006) (25)
Molecular context of a viral T cell determinant within a chimeric bacterial protein alters the diversity of its T cell recognition. (1994) (25)
Appraisal of rabies vaccine potency by determination of in vitro, specific interleukin-2 production. (1991) (24)
In vivo induction of CTL responses by recombinant adenylate cyclase of Bordetella pertussis carrying multiple copies of a viral CD8(+) T-cell epitope. (1999) (24)
Marked enhancement of macrophage activation induced by synthetic muramyl dipeptide (MDP) conjugate using monoclonal anti-MDP antibodies. (1984) (24)
Induction of a Melanoma‐Specific Antibody Response by a Monovalent, but not a Divalent, Synthetic GM2 Neoglycopeptide (2009) (24)
Studies on visceral Leishmania tropica infection in BALB/c mice. I. Clinical features and cellular changes. (1981) (24)
Purification of splenic dendritic cells induces maturation and capacity to stimulate Th1 response in vivo. (2006) (24)
Modulating the immunological properties of a linear B-cell epitope by insertion into permissive sites of the MalE protein. (1996) (23)
The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity (2016) (23)
Expression of Escherichia coli beta-galactosidase in Mycobacterium bovis BCG using an expression system isolated from Mycobacterium paratuberculosis which induced humoral and cellular immune responses. (1992) (22)
Stabilization and enhancement of interleukin-2 in vitro bioactivity by new carriers: supramolecular biovectors. (1994) (22)
Conventional but Not Plasmacytoid Dendritic Cells Foster the Systemic Virus–Induced Type I IFN Response Needed for Efficient CD8 T Cell Priming (2014) (22)
Immunodominance does not result from peptide competition for MHC class II presentation. (1998) (22)
Induction of protective immunity against Mycobacterium tuberculosis by delivery of ESX antigens into airway dendritic cells (2012) (21)
Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses. (2012) (21)
Cross-Priming of T Cell Responses by Synthetic Microspheres Carrying a CD8+ T Cell Epitope Requires an Adjuvant Signal1 (2005) (21)
The adenylate cyclase of Bordetella pertussis: a vector to target antigen presenting cells. (2002) (21)
Expression of heterologous peptides at two permissive sites of the MalE protein: antigenicity and immunogenicity of foreign B-cell and T-cell epitopes. (1992) (21)
Immunodominance of a recombinant T-cell epitope depends on its molecular environment. (1993) (21)
Rabies-specific production of interleukin-2 by peripheral blood lymphocytes from human rabies vaccinees. (1991) (20)
The adjuvant effect of TLR agonists on CD4+ effector T cells is under the indirect control of regulatory T cells (2011) (19)
CD4-independent protective cytotoxic T cells induced in early life by a non-replicative delivery system based on virus-like particles. (2003) (19)
13 – Muramyl Peptides as Immunopharmacological Response Modifiers (1985) (19)
Critical role of neighbouring sequences on the immunogenicity of the C3 poliovirus neutralization epitope expressed at the surface of recombinant bacteria. (1990) (19)
New approaches in vaccine development. (2003) (19)
Inhibition of Phagosome Maturation by Mycobacteria Does Not Interfere with Presentation of Mycobacterial Antigens by MHC Molecules1 (2007) (19)
Efficient Ex Vivo Stimulation of Mycobacterium tuberculosis-Specific T Cells by Genetically Detoxified Bordetella pertussis Adenylate Cyclase Antigen Toxoids (2005) (18)
Production of porcine interleukin-2 and its biological and antigenic relationships with human interleukin-2. (1985) (18)
The fully synthetic glycopeptide MAG-Tn3 therapeutic vaccine induces tumor-specific cytotoxic antibodies in breast cancer patients (2020) (18)
Minor displacements in the insertion site provoke major differences in the induction of antibody responses by chimeric parvovirus-like particles. (1999) (18)
Genetic control of antibody responses induced by recombinant Mycobacterium bovis BCG expressing a foreign antigen (1997) (17)
Inhibition of phagosome maturation by mycobacteria does not interfere with presentation of mycobacterial Ags by MHC molecules. (2007) (17)
Immunogenicity of viral B-cell epitopes inserted into two surface loops of the Escherichia coli K12 LamB protein and expressed in an attenuated aroA strain of Salmonella typhimurium. (1999) (17)
B cells do not present antigen covalently linked to microspheres. (1993) (16)
Interleukin-2 production in vitro: a new approach to the study of rabies vaccine immunogenicity as appraised by testing different glycoprotein presentations. (1988) (16)
mAb against hen egg-white lysozyme regulate its presentation to CD4(+) T cells. (1999) (16)
Enhanced Ex Vivo Stimulation of Mycobacterium tuberculosis-Specific T Cells in Human Immunodeficiency Virus-Infected Persons via Antigen Delivery by the Bordetella pertussis Adenylate Cyclase Vector (2007) (16)
Recognition of Mycobacterial Antigens Delivered by Genetically Detoxified Bordetella pertussis Adenylate Cyclase by T Cells from Cattle with Bovine Tuberculosis (2004) (15)
Enhancement by muramyl dipeptide of in vitro nude mice responses to a T-dependent antigen. (1979) (15)
A Universal Influenza Vaccine Can Lead to Disease Exacerbation or Viral Control Depending on Delivery Strategies (2016) (15)
Immunogenicity of viral B- and T-cell epitopes expressed in recombinant bacterial proteins. (1994) (15)
Overcoming the crypticity of a viral T cell determinant by insertion into a chimeric bacterial protein. (1996) (15)
Immobilized cytokines as biomaterials for manufacturing immune cell based vaccines. (2008) (15)
Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate. (2016) (15)
[32] Bordetella pertussis adenylate cyclase toxin: A vehicle to deliver CD8-positive T-cell epitopes into antigen-presenting cells (2000) (14)
Dendritic Cells Present Exogenous Virus-like Particles to CD 8 T Cells and Subsequently Express CD 8 and CD 205 Molecules (2002) (14)
In vitro effects of lipopolysaccharides and mycobacterial cell wall components on swine alveolar macrophages (1983) (14)
Control by H-2 genes of the Th1 response induced against a foreign antigen expressed by attenuated Salmonella typhimurium (1996) (14)
Parameters affecting the immunogenicity of recombinant T cell epitopes inserted into hybrid proteins. (1997) (14)
Cellular basis of the resistance of newborn mice to the pathogenic effects of anti-CD3 treatment. (1991) (14)
Lack of H-2 gene influence on mouse susceptibility to secondary alveolar echinococcosis. (1997) (13)
Bordetella pertussis adenylate cyclase delivers chemically coupled CD8+ T-cell epitopes to dendritic cells and elicits CTL in vivo. (2004) (13)
Partial Activation of Neonatal CD11c+ Dendritic Cells and Induction of Adult-Like CD8+ Cytotoxic T Cell Responses by Synthetic Microspheres1 (2004) (12)
Polyclonal antibody-forming cell activation and immunomodulation of the in vitro immune response induced by streptococcal extracellular products. (1983) (12)
Nonspecific immunoprevention of L1210 leukemia by cord factor (6-6′ dimycolate of trehalose) administered in a metabolizable oil (1976) (11)
Induction of HLA-A2-restricted CTL responses by a tubular structure carrying human melanoma epitopes. (2002) (11)
Visceral Leishmania tropica infection of BALB/c mice: cellular analysis of in vitro unresponsiveness to sheep erythrocytes (1982) (10)
Cytotoxic T cell response to Mengo virus in mice: effector cell phenotype and target proteins. (1995) (10)
Bordetella pertussis adenylate cyclase toxin: a vehicle to deliver CD8-positive T-cell epitopes into antigen-presenting cells. (2000) (10)
[New technologies for vaccine development]. (2007) (10)
Lack of MHC class II molecules favors CD8+ T-cell infiltration into tumors associated with an increased control of tumor growth (2017) (10)
Comparison of immunomodulatory activities in mice and guinea pigs of a synthetic desmuramyl peptidolipid triglymyc (1984) (10)
Induction of antibodies directed against self and altered-self determinants by a synthetic adjuvant, muramyl dipeptide and some of its derivatives. (1980) (9)
Restricted specificity of anti-V3 antibodies induced in humans by HIV candidate vaccines. (1997) (9)
Immune responses to hybrid maltose-binding proteins. (1993) (9)
Design, Synthesis, and Immunological Evaluation of a Multicomponent Construct Based on a Glycotripeptoid Core Comprising B and T Cell Epitopes and a Toll-like Receptor 7 Agonist That Elicits Potent Immune Responses. (2018) (9)
Are there receptors for MDP at the macrophage surface (1986) (9)
Evaluation of the induction of specific cytotoxic T lymphocytes following immunization of F1 hybrid mice with rabies antigens. (1989) (9)
Inhibition of mitogen-induced polyclonal activation by by a synthetic adjuvant, muramyl dipeptide (MDP). (1980) (9)
Tumor therapy in mice by using a tumor antigen linked to modulin peptides from Staphylococcus epidermidis. (2010) (9)
Expression and immune response to foreign epitopes in bacteria. Perspectives for live vaccine development. (1997) (9)
Immune Profiling Enables Stratification of Patients With Active Tuberculosis Disease or Mycobacterium tuberculosis Infection (2020) (9)
Antigens linked to synthetic microspheres induce immune responses in primates in the absence of adjuvant. (1996) (8)
Effects of intravenous injection of BCG or Freund's complete adjuvant on swine alveolar macrophages. (1983) (7)
Alloantigen pretreatment induces a down‐regulation of the in vivo subsequent development of cytotoxic T lymphocytes directed against linked alloantigens (1989) (7)
Complexes of Streptavidin-Fused Antigens with Biotinylated Antibodies Targeting Receptors on Dendritic Cell Surface: A Novel Tool for Induction of Specific T-Cell Immune Responses (2012) (7)
Induction of anti-Tat neutralizing antibodies by the CyaA vector targeting dendritic cells: influence of the insertion site and of the delivery of multicopies of the dominant Tat B-cell epitope. (2010) (6)
High Frequency of CD 4 T Cells Specific for the TB 10 . 4 Protein Correlates with Protection against Mycobacterium tuberculosis Infection (2006) (6)
IL-17 suppresses the therapeutic activity of cancer vaccines through the inhibition of CD8+ T-cell responses (2020) (6)
Activation of B cells by 1 microm particulate lysozyme or peptides: a Th-dependent pathway requiring CD40-CD40 ligand interaction. (1998) (6)
Homogeneous processing and presentation of a recombined T cell epitope in inbred mice of different non-MHC genetic background. (1996) (5)
Molecular and cellular parameters controlling the immunogenicity of foreign B- or T-cell epitopes expressed by recombinant vectors. (1994) (5)
Structural requirements for the induction of "immunological castration" by linear monomeric LHRH-lys-MDP administered in saline. (1987) (5)
Challenges and issues in new vaccine development. (2002) (5)
CD 4-Independent Protective Cytotoxic T Cells Induced in Early Life by a Non-Replicative Delivery System Based on Virus-like Particles (2003) (4)
Immunomodulation of macrophages by muramyl peptides: recent findings concerning somnogenic activity of muramyl peptides and monokine. (1984) (4)
Control by Ig genes of the responsiveness to a neutralization viral B cell epitope. (1997) (4)
Treatment by CpG or Flt3-ligand does not affect mouse susceptibility to BSE prions (2008) (4)
Alloantigen‐specific regulation of cytotoxic T cell responses is mediated through the induction of clonal anergy of CD8+ T cells (1992) (3)
Prevention of low dose streptozotocin induced diabetes by muramyl dipeptide. (1988) (3)
Bacterial vectors to target and/or purify polypeptides: their use in immunological studies. (1991) (3)
Selective regulation of lymphokines production by MDP: A key to its immunomodulatory activity? (1985) (3)
In vivo OVA-specific Cytotoxic CD8+ T Cell Killing Assay (2016) (3)
Fine specificity of anti-V3 antibodies induced in chimpanzees by HIV candidate vaccines. (1998) (3)
Enhancement of Antibody-Dependent Cell-Mediated Cytotoxicity (ADCMC) by an Interphase Material (IPM) extracted from a non-pathogenic strain of mycobacteria (1977) (3)
A potential anti-pregnancy vaccine built by conjugation of the beta-subunit of human chorionic gonadotropin to adjuvant-active muramyl peptide. (1987) (3)
CD4 T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against PulmonaryMycobacterium tuberculosis Infection (2018) (2)
Increased adjuvanticity of MDP by conjugation to mannose: The specific targeting of MDP to macrophages could markedly enhance its activity (1985) (2)
Delivery of recombinant adenylate cyclase of Bordetella pertussis carrying a foreign epitope in the MHC class I processing pathway (1998) (2)
Host Immune System Interaction between Mycobacteria and the on the Mycobacterium tuberculosis ( RD 1 ) of Influence of ESAT-6 Secretion System 1 (2005) (2)
The T-cell receptor repertoire of tumor-infiltrating regulatory T lymphocytes is skewed towards public sequences Short title: T-cell repertoire of tumor-infiltrating Treg Authors (2012) (2)
Corrigendum: A Universal Influenza Vaccine Can Lead to Disease Exacerbation or Viral Control Depending on Delivery Strategies (2017) (2)
Anti-Tumor Immunity Provided by a Synthetic Multiple Antigenic Glycopeptide Displaying a TriTn TriTn TriTn Glycotope 1 (2001) (2)
Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines (2018) (2)
Vaccination against HIV and SIV. (1990) (2)
The EFIS vaccination task force expert report (2021) (1)
Regulation of antibody production by suppressor T cells (1989) (1)
IMMUNOSUPPRESSIVE PROPERTIES OF MURAMYL PEPTIDES (1986) (1)
Endosome-to-Cytosol Pathway Virus-Like Particles Using an In Vivo , Dendritic Cells Can Cross-Present (2003) (1)
Role of major and minor histocompatibility antigens in the suppression of alloreactive cytotoxic responses induced by alloantigen pretreatment. (1990) (1)
Preparation for Hapten Help by Glucan, Muramyl Dipeptide, and Its L‐ala‐Glycerol‐Mycolate Derivative (1985) (1)
Anti-viral protection conferred by recombinant adenylate cyclase toxins from Bordetella pertussis carrying a CD8+ T cell epitope from LCMV (1997) (1)
Towards a rational approach to vaccine development (2010) (1)
Recombinant proteins of human papillomavirus epitopes inserted in an Adenylatecyclase protein or carry in its fragments, and their use terapeutischen. (2004) (0)
Traitement des infections urinaires basses par la norfloxacine (1992) (0)
Proteinaceous vectors for introducing molecules in cells CD11b exprimirende (2000) (0)
A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals (2019) (0)
Recombinant adenylate cyclase toxin induced by bordetella t-cell respond to tumoral antigenic (2004) (0)
Iconographies supplémentaires de l'article : Dectin-1 activation unlocks IL12A expression and reveals the T H 1 potency of neonatal dendritic cells (2015) (0)
Mucosal immunity: immune response (WS-066) Chairpersons: Noriko Tsuji, Ichiro Takahashi (2010) (0)
Glycopeptide carbohydrate antigen multiple, vaccine comprising the same and their use. (1998) (0)
Induction de protection contre les infections virales (1991) (0)
Suppressor T cells: an appraisal of their role by in vivo elimination. (1989) (0)
Method for producing leishmania fractions possessing immunogenic and lymphoproliferative activity and fractions obtained by this method (1987) (0)
responses in vivo after viral stimulation Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell (2013) (0)
[Analysis of in vitro delivering CD8+ T epitopes by attenuated bacteria]. (2006) (0)
Cyclase Carrying a Cytotoxic T Cell Epitope Adenylate Bordetella pertussis Recombinant Therapy of Murine Tumors with (1999) (0)
Compositions based on a combination of liposomes and lymphokine presenting immunostimulating properties and their applications in human and veterinary medicine (1987) (0)
Synthetic Microspheres Cytotoxic T Cell Responses by + CD8Dendritic Cells and Induction of Adult-Like + Partial Activation of Neonatal CD11c (2004) (0)
Bordetella pertussis of Protein by Recombinant Adenylate Cyclase Human Immunodeficiency Virus Type 1 Tat T-Cell Responses following Delivery of + Th 1-Polarized and CD 4-Independent CD 8 Induction of Neutralizing Antibodies and (2005) (0)
Type I IFN Response Needed for Efficient Induced - Cells Foster the Systemic Virus Conventional but Not Plasmacytoid Dendritic (2014) (0)
Dendritic Cells Cytotoxic T Cell Responses by Neonatal Efficient In Vivo Priming of Specific (2022) (0)
respond to antigen-containing microparticles and their use for the induction of humoral or cellular (1993) (0)
[In-vivo dynamic changes of antigen presenting cells infected with recombinant attenuated Salmonella typhimurium expressing green fluorescent protein]. (2003) (0)
Response Infection Does Not Affect the Memory Bacille Calmette-Guérin Mycobacterium bovis Associated with the Chronicity of The Shift of Th 1 to Th 2 (2003) (0)
Multiple, carbohydrate-containing glycopeptide-antigenic, developed from vaccines and their use (1998) (0)
Cell Epitope Requires an Adjuvant Signal T + Synthetic Microspheres Carrying a CD 8 Cross-Priming of T Cell Responses (2005) (0)
Use fibronectin EDA domain (2006) (0)
Bordetella pertussis components given with carrier priming can overcome epitope suppression in synthetic vaccine models (1985) (0)
Microenvironment and Immunology The T-cell Receptor Repertoire of Tumor-In fi ltrating Regulatory T Lymphocytes Is Skewed Toward Public Sequences (2012) (0)
Regulation of IL2 production by muramyl dipeptide and derivatives (1982) (0)
Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells (2018) (0)
Recombinant viral pseudo-particles and their use as vaccine or as an anti-tumor active ingredients (1996) (0)
and Acquired Immunity Mycobacteria In Vivo That Trigger Innate Dendritic Cells Are Host Cells for (2002) (0)
Method for preparing conjugates of carbohydrate-glycopeptide multiple antigen (2012) (0)
bovis BCG vaccine strains. immunized with five different Mycobacterium Comparison of immune responses of mice (2013) (0)
Molecular and cellular targeting in the expression of foreign polypeptides in bacteria (1992) (0)
Displaying a Tri-Tn Glycotope Synthetic Multiple Antigenic Glycopeptide Anti-Tumor Immunity (2001) (0)
685 IMMUNIZATION AGAINST HEPATITIS C VIRUS USING A PEPTIDE FROM NS3 PROTEIN LINKED TO MODULINS DERIVED FROM STAPHYLOCOCCUS EPIDERMIDIS (2010) (0)
Non-replicative parvovirus-like particles carrying a single CD8+ CTL epitope from LCMV confer protection against lethal viral infection (1997) (0)
Immunogenicity of recombinant hybrid proteins in attenuated Salmonella typhimurium (1992) (0)
absence of CD4+ T-cell help TLR3 ligand stimulates fully functional memory CD8+ T-cells in the (2013) (0)
Mutant CyaA polypeptides and polypeptide derivatives suitable for the delivery of immunogenic molecu (2011) (0)
TLR9 activation is required for cytotoxic response elicited by baculovirus capsid display (2022) (0)
New non-replicative vectors for CTL activation (1998) (0)
Type I IFN Adaptive Immune Responses by Inducing Insect Baculoviruses Strongly Potentiate (2007) (0)
Antibody-Mediated Antigen Presentation to T and Antigen Determines the Efficiency of The Rate of Dissociation Between Antibody (1998) (0)
to CD8+ cytotoxic T cells. allows in vitro presentation of a foreign epitope adenylate cyclase of Bordetella pertussis Cell-invasive activity of epitope-tagged (2013) (0)
Pneumopathies communautaires de l'adulte (1995) (0)
Identification of RD1 and RD5 regions associated with virulence that allows the development of improved vaccines m. bovis BCG and m. microti. (2002) (0)
Identification of T cell epitopes of MalE protein expressed by recombinant Mycobacterium bovis BCG (2002) (0)
Lymphocyte activation by streptococcal exoproteins (1982) (0)
Recombinant mutant for induction of specific immune responses (1993) (0)

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