Claudio Franceschi

Claudio Franceschi's AcademicInfluence.com Rankings

Claudio Franceschi

Philosophy

#2851

World Rank

#4744

Historical Rank

Logic

#816

World Rank

#1361

Historical Rank

philosophy Degrees

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Philosophy

Claudio Franceschi's Degrees

PhD Biomedical Sciences University of Bologna
Doctorate Medicine University of Bologna

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Claudio Franceschi's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Inflamm‐aging: An Evolutionary Perspective on Immunosenescence (2000) (3720)
Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. (2014) (2422)
Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans (2007) (1762)
Chronic inflammation in the etiology of disease across the life span (2019) (1434)
Geroscience: Linking Aging to Chronic Disease (2014) (1391)
Inflammaging: a new immune–metabolic viewpoint for age-related diseases (2018) (1180)
Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians (2010) (1150)
A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1). (1993) (1039)
JC‐1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess ΔΨ changes in intact cells: implications for studies on mitochondrial functionality during apoptosis (1997) (991)
Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes? (2018) (746)
Increased cytokine production in mononuclear cells of healthy elderly people (1993) (632)
Gut Microbiota and Extreme Longevity (2016) (534)
The immunology of exceptional individuals: the lesson of centenarians. (1995) (519)
Inflammaging and ‘Garb-aging’ (2017) (515)
Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in aging. (2000) (496)
Interventions to Slow Aging in Humans: Are We Ready? (2015) (462)
The Continuum of Aging and Age-Related Diseases: Common Mechanisms but Different Rates (2018) (459)
Innate immunity and inflammation in ageing: a key for understanding age-related diseases (2005) (458)
Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space. (2000) (453)
Inflamm‐ageing and lifelong antigenic load as major determinants of ageing rate and longevity (2005) (446)
Mitochondria are selective targets for the protective effects of heat shock against oxidative injury. (1996) (419)
Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. (2003) (417)
Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice (2005) (410)
Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans (1999) (394)
The immune system in extreme longevity (2008) (393)
Inflammaging as a major characteristic of old people: can it be prevented or cured? (2007) (387)
Accelerated epigenetic aging in Down syndrome (2015) (381)
A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages. (2005) (353)
Expansion of cytotoxic CD8+ CD28− T cells in healthy ageing people, including centenarians (1996) (342)
Centenarians as a model for healthy aging. (2003) (341)
T cells and aging, January 2002 update. (2002) (328)
Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence (2017) (327)
Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries (2020) (326)
Methylation of ELOVL2 gene as a new epigenetic marker of age (2012) (326)
Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control. (2003) (321)
Inflammation markers predicting frailty and mortality in the elderly. (2006) (320)
The aging thyroid. (1995) (319)
Undulating changes in human plasma proteome profiles across the lifespan (2019) (317)
Aging of the immune system as a prognostic factor for human longevity. (2008) (316)
The network and the remodeling theories of aging: historical background and new perspectives (2000) (313)
Ageing of the human metaorganism: the microbial counterpart (2011) (310)
A gender–dependent genetic predisposition to produce high levels of IL‐6 is detrimental for longevity (2001) (303)
Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons. (2003) (302)
The neuroimmunology of stress from invertebrates to man (1996) (300)
Protective effect of N-acetylcysteine in tumor necrosis factor-alpha-induced apoptosis in U937 cells: the role of mitochondria. (1995) (297)
Plasma antioxidants and longevity: a study on healthy centenarians. (2000) (288)
Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition (2017) (283)
Risk factors and incidence of postoperative delirium in elderly patients after elective and emergency surgery (2010) (271)
Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for “inflamm‐aging” (2014) (260)
Functional metagenomic profiling of intestinal microbiome in extreme ageing (2013) (257)
Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring (2015) (244)
Do men and women follow different trajectories to reach extreme longevity? (2000) (242)
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age (2014) (238)
CD45 isoforms expression on CD4+ and CD8+ T cells throughout life, from newborns to centenarians: implications for T cell memory (1996) (235)
Vaccination in the elderly: The challenge of immune changes with aging. (2018) (232)
Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis (2018) (228)
The Three Genetics (Nuclear DNA, Mitochondrial DNA, and Gut Microbiome) of Longevity in Humans Considered as Metaorganisms (2014) (227)
Gender-specific association between −1082 IL-10 promoter polymorphism and longevity (2002) (227)
Complex alteration of thyroid function in healthy centenarians. (1993) (224)
The immune system in the elderly (2004) (220)
Identification of a geographic area characterized by extreme longevity in the Sardinia island: the AKEA study (2004) (220)
Correction: Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians (2010) (219)
Ageing and gut microbes: perspectives for health maintenance and longevity. (2013) (219)
Thyroid and other organ-specific autoantibodies in healthy ceritenarians (1992) (215)
Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile (2013) (213)
Inflamm-aging, cytokines and aging: state of the art, new hypotheses on the role of mitochondria and new perspectives from systems biology. (2006) (212)
Aging, Longevity, Inflammation, and Cancer (2004) (212)
Reconfiguration of DNA methylation in aging (2015) (212)
Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians (2005) (207)
The Genetics of Human Longevity (2006) (203)
Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of Lipids, Amino Acids, and Gut Microbiota Metabolism (2013) (200)
Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains (2006) (200)
Age-related differences in the expression of circulating microRNAs: miR-21 as a new circulating marker of inflammaging (2012) (199)
Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence (2003) (197)
N-glycomic biomarkers of biological aging and longevity: A link with inflammaging (2013) (195)
Oxidative stress and the ageing endocrine system (2013) (195)
Mitochondrial modifications during rat thymocyte apoptosis: a study at the single cell level. (1994) (192)
Inflamm-ageing (2013) (189)
Lipoprotein(a) and lipoprotein profile in healthy centenarians: a reappraisal of vascular risk factors (1998) (189)
Immunosenescence and Immunogenetics of Human Longevity (2008) (188)
Role of epigenetics in human aging and longevity: genome-wide DNA methylation profile in centenarians and centenarians’ offspring (2013) (186)
MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling (2013) (182)
Interleukin-6 gene alleles affect the risk of Alzheimer’s disease and levels of the cytokine in blood and brain (2003) (182)
Immune system, cell senescence, aging and longevity--inflamm-aging reappraised. (2013) (180)
Massive Load of Functional Effector CD4+ and CD8+ T Cells against Cytomegalovirus in Very Old Subjects1 (2007) (179)
MARK-AGE biomarkers of ageing (2015) (179)
Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 −1082 promoter SNP and its interaction with TNF-α −308 promoter SNP (2003) (177)
Fibroblast cultures from healthy centenarians have an active proteasome (2000) (177)
Genome‐wide linkage analysis for human longevity: Genetics of Healthy Aging Study (2013) (174)
Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease (2001) (173)
MicroRNAs linking inflamm-aging, cellular senescence and cancer (2013) (172)
Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes (2003) (171)
Cytomegalovirus Infection (2007) (171)
Gender, aging and longevity in humans: an update of an intriguing/neglected scenario paving the way to a gender-specific medicine (2016) (168)
Immunobiography and the Heterogeneity of Immune Responses in the Elderly: A Focus on Inflammaging and Trained Immunity (2017) (167)
The invertebrate phagocytic immunocyte: clues to a common evolution of immune and neuroendocrine systems. (1997) (161)
Extremely low frequency pulsed electromagnetic fields increase cell proliferation in lymphocytes from young and aged subjects. (1989) (160)
Mitochondrial membrane potential and DNA stainability in human sperm cells: a flow cytometry analysis with implications for male infertility. (1998) (159)
THYMIC HORMONE DEFICIENCY IN NORMAL AGEING AND DOWN'S SYNDROME: IS THERE A PRIMARY FAILURE OF THE THYMUS? (1984) (159)
A meta-analysis of genome-wide association studies identifies multiple longevity genes (2019) (158)
Increased brain-predicted aging in treated HIV disease (2017) (158)
The treatment of osteosarcoma of the extremities: Twenty year's experience at the istituto ortopedico rizzoli (1981) (153)
Age-related inflammation: the contribution of different organs, tissues and systems. How to face it for therapeutic approaches. (2010) (153)
Biomarkers of immunosenescence within an evolutionary perspective: the challenge of heterogeneity and the role of antigenic load (1999) (145)
Low vitamin D status, high bone turnover, and bone fractures in centenarians. (2003) (144)
Chemokines, sTNF-Rs and sCD30 serum levels in healthy aged people and centenarians (2001) (144)
Gut microbiota changes in the extreme decades of human life: a focus on centenarians (2017) (144)
Inflammaging and Cancer: A Challenge for the Mediterranean Diet (2015) (143)
Genes, demography, and life span: the contribution of demographic data in genetic studies on aging and longevity. (1999) (143)
A Cross-Sectional Analysis of Body Composition Among Healthy Elderly From the European NU-AGE Study: Sex and Country Specific Features (2018) (140)
HAPLOFIND: A New Method for High‐Throughput mtDNA Haplogroup Assignment (2013) (137)
What accounts for the wide variation in life span of genetically identical organisms reared in a constant environment? (2005) (137)
Novel loci and pathways significantly associated with longevity (2016) (136)
Cytometric analysis of immunosenescence. (1997) (132)
Opposite effects of interleukin 10 common gene polymorphisms in cardiovascular diseases and in successful ageing: genetic background of male centenarians is protective against coronary heart disease (2004) (132)
Changes in circuIating B cells and immunoglobulin cIasses and subcIasses in a healthy aged popuIation (1992) (131)
Immunogenetics, Gender, and Longevity (2006) (131)
Gene polymorphism affecting α1‐antichymotrypsin and interleukin‐1 plasma levels increases Alzheimer's disease risk (2000) (130)
Interleukin-10 promoter polymorphism in sporadic Alzheimer's disease (2003) (130)
New advances in CMV and immunosenescence (2014) (130)
Role of Toll-like receptor 4 in acute myocardial infarction and longevity. (2004) (129)
Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral blood lymphocytes during acute HIV syndrome (1997) (129)
Apoptosis‐like, reversible changes in plasma membrane asymmetry and permeability, and transient modifications in mitochondrial membrane potential induced by curcumin in rat thymocytes (1998) (128)
Paradoxes in longevity: sequence analysis of mtDNA haplogroup J in centenarians (2001) (127)
Curcumin in Cell Death Processes: A Challenge for CAM of Age-Related Pathologies (2007) (126)
Diverse Effect of Inflammatory Markers on Insulin Resistance and Insulin‐Resistance Syndrome in the Elderly (2004) (124)
Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2) (1998) (123)
A Study of Serum Immunoglobulin Levels in Elderly Persons That Provides New Insights into B Cell Immunosenescence (2006) (123)
What evidence is there for the existence of individual genes with antagonistic pleiotropic effects? (2005) (121)
Inflammaging and human longevity in the omics era (2017) (119)
Different contribution of EBV and CMV infections in very long-term carriers to age-related alterations of CD8+ T cells (2004) (118)
Evidence for Sub-Haplogroup H5 of Mitochondrial DNA as a Risk Factor for Late Onset Alzheimer's Disease (2010) (118)
Extremely low frequency pulsed electromagnetic fields increase interleukin‐2 (IL‐2) utilization and IL‐2 receptor expression in mitogen‐stimulated human lymphocytes from old subjects (1989) (117)
Aging and Imaging Assessment of Body Composition: From Fat to Facts (2020) (117)
Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity (2015) (117)
Combating inflammaging through a Mediterranean whole diet approach: The NU-AGE project's conceptual framework and design (2014) (116)
Precocious aging of the immune system in Down syndrome: alteration of B lymphocytes, T-lymphocyte subsets, and cells with natural killer markers. (2005) (116)
Cell proliferation, cell death and aging (1989) (116)
Vitamin E–gene interactions in aging and inflammatory age-related diseases: Implications for treatment. A systematic review (2014) (115)
Age-dependent modifications of Type 1 and Type 2 cytokines within virgin and memory CD4+ T cells in humans (2006) (114)
The G/C915 polymorphism of transforming growth factor β1 is associated with human longevity: a study in Italian centenarians (2004) (113)
Inhibition of apoptosis by zinc: a reappraisal. (1992) (112)
Resistance to apoptosis in CTLL-2 cells constitutively expressing c-Myb is associated with induction of BCL-2 expression and Myb-dependent regulation of bcl-2 promoter activity. (1997) (112)
In Vitro Exposure of Human Lymphocytes to 900 MHz CW and GSM Modulated Radiofrequency: Studies of Proliferation, Apoptosis and Mitochondrial Membrane Potential (2004) (112)
Human aging and longevity are characterized by high levels of mitokines. (2018) (112)
Telomere length in fibroblasts and blood cells from healthy centenarians. (1999) (111)
Thymic output and functionality of the IL‐7/IL‐7 receptor system in centenarians: implications for the neolymphogenesis at the limit of human life (2006) (110)
Mediterranean diet and inflammaging within the hormesis paradigm (2017) (110)
Allele frequencies of +874T→A single nucleotide polymorphism at the first intron of interferon-γ gene in a group of Italian centenarians (2002) (110)
Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia (2011) (109)
Serum profiling of healthy aging identifies phospho- and sphingolipid species as markers of human longevity (2014) (108)
Age-dependent alteration in muscle regeneration: the critical role of tissue niche (2013) (107)
An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging (2021) (106)
Age-related expansion of functionally inefficient cells with markers of natural killer activity in Down's syndrome. (1991) (106)
Serum N-glycan profile shift during human ageing (2010) (105)
Human intestinal microbiota: cross-talk with the host and its potential role in colorectal cancer (2011) (105)
Long-term immune-endocrine effects of bereavement: relationships with anxiety levels and mood (2003) (104)
Apoptosis and spermatogenesis: evidence from an in vivo model of testosterone withdrawal in the adult rat. (1994) (102)
AKEntAnnos. The Sardinia Study of Extreme Longevity (1999) (102)
Gene polymorphisms predicting high plasma levels of coagulation and fibrinolysis proteins. A study in centenarians. (1997) (102)
N-glycomic changes in serum proteins during human aging. (2007) (102)
Long-term immunologic effects of thymectomy in patients with myasthenia gravis. (1999) (101)
Mitochondria, aging and longevity – a new perspective (2001) (101)
Genetics of Healthy Aging in Europe (2007) (101)
The −174 C/G locus affects in vitro/in vivo IL-6 production during aging (2002) (101)
Oxygen radicals induce stress proteins and tolerance to oxidative stress in human lymphocytes. (1996) (100)
The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death (2004) (99)
Autocrine nerve growth factor protects human keratinocytes from apoptosis through its high affinity receptor (TRK): a role for BCL-2. (1997) (99)
Association of the mitochondrial DNA haplogroup J with longevity is population specific (2004) (99)
Identifying the genomic determinants of aging and longevity in human population studies: Progress and challenges (2013) (98)
Is Aging As Complex As It Would Appear? (1992) (97)
Metallothioneins/PARP-1/IL-6 interplay on natural killer cell activity in elderly: parallelism with nonagenarians and old infected humans. Effect of zinc supply (2003) (97)
Exposure to low frequency pulsed electromagnetic fields increases interleukin-1 and interleukin-6 production by human peripheral blood mononuclear cells. (1993) (97)
Hemopoiesis in healthy old people and centenarians: well-maintained responsiveness of CD34+ cells to hemopoietic growth factors and remodeling of cytokine network. (2000) (97)
Earthworm leukocytes that are not phagocytic and cross-react with several human epitopes can kill human tumor cell lines. (1996) (97)
Gene expression changes in human cells after exposure to mobile phone microwaves (2006) (96)
Metabolic age modelling: the lesson from centenarians (2000) (95)
Pro-opiomelanocortin-derived peptides, cytokines, and nitric oxide in immune responses and stress: an evolutionary approach. (1997) (95)
The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific (2013) (95)
The aging gut microbiota: New perspectives (2011) (95)
Effect of interleukin-6 polymorphisms on human longevity: A systematic review and meta-analysis (2009) (94)
C60 carboxyfullerene exerts a protective activity against oxidative stress-induced apoptosis in human peripheral blood mononuclear cells. (2000) (94)
-174 G>C polymorphism of interleukin 6 gene promoter affects interleukin 6 serum level in patients with colorectal cancer. (2003) (93)
Effect of Etanercept on Insulin Sensitivity in Nine Patients with Psoriasis (2007) (93)
In vivo accumulation of sulfated glycoprotein 2 mRNA in rat thymocytes upon dexamethasone-induced cell death. (1991) (92)
Age- and glycemia-related miR-126-3p levels in plasma and endothelial cells (2014) (92)
From lifetime to evolution: timescales of human gut microbiota adaptation (2014) (92)
The −174G/C polymorphism of IL-6 is useful to screen old subjects at risk for atherosclerosis or to reach successful ageing (2004) (92)
Serum IL-1beta levels in health and disease: a population-based study. 'The InCHIANTI study'. (2003) (92)
The A3 adenosine receptor mediates cell spreading, reorganization of actin cytoskeleton, and distribution of Bcl-XL: studies in human astroglioma cells. (1997) (91)
Apoptosis--programmed cell death: a role in the aging process? (1992) (91)
In vitro peroxidase oxidation induces stable dimers of beta-amyloid (1-42) through dityrosine bridge formation. (1999) (91)
Impact of personalized diet and probiotic supplementation on inflammation, nutritional parameters and intestinal microbiota - The "RISTOMED project": Randomized controlled trial in healthy older people. (2015) (90)
Discovery of novel and selective SIRT6 inhibitors. (2014) (89)
Leukocyte telomere length is associated with complications of Type 2 diabetes mellitus (2011) (88)
Identification of a DNA methylation signature in blood cells from persons with Down Syndrome (2014) (87)
Corticotropin-releasing hormone modulates cytokines release in cultured human peripheral blood mononuclear cells. (1993) (87)
Modulation of Apoptosis by Adenosine in the Central Nervous System: a Possible Role for the A3 Receptor (1997) (87)
A novel action for adenosine: apoptosis of astroglial cells in rat brain primary cultures. (1995) (86)
1800 MHz radiofrequency (mobile phones, different Global System for Mobile communication modulations) does not affect apoptosis and heat shock protein 70 level in peripheral blood mononuclear cells from young and old donors (2004) (85)
Intense Antiextracellular Adaptive Immune Response to Human Cytomegalovirus in Very Old Subjects with Impaired Health and Cognitive and Functional Status (2010) (85)
Pathophysiology of ageing, longevity and age related diseases (2007) (85)
Neuroinflammation and the genetics of Alzheimer’s disease: The search for a pro-inflammatory phenotype (2001) (85)
N-Glycomic Changes in Serum Proteins in Type 2 Diabetes Mellitus Correlate with Complications and with Metabolic Syndrome Parameters (2015) (84)
Genes and longevity: lessons from studies of centenarians. (2000) (84)
Presence of ACTH and β-endorphin immunoreactive molecules in the freshwater snail Planorbarius corneus (L.) (Gastropoda, Pulmonata) and their possible role in phagocytosis (1990) (84)
Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells (2020) (83)
Family clustering in Sardinian longevity: A genealogical approach (2006) (83)
Deficiency of autologous mixed lymphocyte reactions and serum thymic factor level in Down's syndrome. (1981) (83)
Association between the interleukin-1β polymorphisms and Alzheimer's disease: A systematic review and meta-analysis (2008) (83)
Retention of the p53 codon 72 arginine allele is associated with a reduction of disease-free and overall survival in arginine/proline heterozygous breast cancer patients. (2003) (83)
HLA, aging, and longevity: a critical reappraisal. (2000) (83)
Present and future of anti-ageing epigenetic diets (2014) (83)
Inflamm-aging of the stem cell niche: breast cancer as a paradigmatic example: breakdown of the multi-shell cytokine network fuels cancer in aged people. (2012) (82)
The evolution of the adipose tissue: a neglected enigma. (2011) (82)
Immunoproteasomes and immunosenescence (2003) (82)
Systematic review by meta-analyses on the possible role of TNF-α polymorphisms in association with Alzheimer's disease (2009) (82)
Have the oldest old adults ever been frail in the past? A hypothesis that explains modern trends in survival. (2001) (82)
Von Willebrand factor in Italian centenarians. (2003) (81)
Numerical and functional alterations of circulating γδ T lymphocytes in aged people and centenarians (2002) (81)
Presence of several cytokine-like molecules in molluscan hemocytes. (1993) (80)
Low circulating IGF-I bioactivity is associated with human longevity: Findings in centenarians’ offspring (2012) (80)
Association between longevity and cytokine gene polymorphisms. A study in Sardinian centenarians (2004) (79)
Decreased susceptibility to oxidative stress-induced apoptosis of peripheral blood mononuclear cells from healthy elderly and centenarians (2001) (79)
The role of low-grade inflammation and metabolic flexibility in aging and nutritional modulation thereof: A systems biology approach (2014) (79)
Carboxyfullerenes protect human keratinocytes from ultraviolet-B-induced apoptosis. (2000) (78)
Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system (2010) (78)
Perilipin 2 and Age-Related Metabolic Diseases: A New Perspective (2016) (78)
Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjects (2013) (78)
Mitochondrial DNA involvement in human longevity. (2006) (77)
Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairment (2001) (77)
Inherited Variability of the Mitochondrial Genome and Successful Aging in Humans (2000) (76)
Genes, ageing and longevity in humans: Problems, advantages and perspectives (2006) (76)
The Genetic Variability of APOE in Different Human Populations and Its Implications for Longevity (2019) (75)
Complexity of anti-immunosenescence strategies in humans. (2006) (75)
The unusual genetics of human longevity. (2006) (75)
The interleukin-6 -174 G>C promoter polymorphism is associated with a higher risk of death after an acute coronary syndrome in male elderly patients. (2005) (74)
Acceleration of leukocytes’ epigenetic age as an early tumor and sex-specific marker of breast and colorectal cancer (2017) (74)
Do people living with HIV experience greater age advancement than their HIV-negative counterparts? (2018) (74)
Mitochondrial heterogeneity during staurosporine-induced apoptosis in HL60 cells: analysis at the single cell and single organelle level. (2000) (74)
Mediterranean-Style Diet Improves Systolic Blood Pressure and Arterial Stiffness in Older Adults (2019) (74)
Apoptosis by 2-chloro-2′-deoxy-adenosine and 2-chloro-adenosine in human peripheral blood mononuclear cells (1998) (74)
Immunogenetics of longevity. Is major histocompatibility complex polymorphism relevant to the control of human longevity? A review of literature data (2001) (73)
Gut microbiota as a candidate for lifespan extension: an ecological/evolutionary perspective targeted on living organisms as metaorganisms (2011) (73)
Activation of the A3 adenosine receptor affects cell cycle progression and cell growth (2000) (73)
The highly reducing sugar 2-deoxy-D-ribose induces apoptosis in human fibroblasts by reduced glutathione depletion and cytoskeletal disruption. (1998) (72)
Low insulin resistance and preserved β-cell function contribute to human longevity but are not associated with TH–INS genes (2001) (72)
Inhibin and activin modulate human monocyte chemotaxis and human lymphocyte interferon-gamma production. (1991) (72)
Elevated gut microbiome abundance of Christensenellaceae, Porphyromonadaceae and Rikenellaceae is associated with reduced visceral adipose tissue and healthier metabolic profile in Italian elderly (2021) (71)
The extreme longevity: The state of the art in Italy (2008) (71)
The frequency of Klotho KL-VS polymorphism in a large Italian population, from young subjects to centenarians, suggests the presence of specific time windows for its effect (2010) (71)
Why do centenarians escape or postpone cancer? The role of IGF-1, inflammation and p53 (2009) (71)
Immunosenescence in humans: deterioration or remodelling? (1995) (71)
Metformin improves putative longevity effectors in peripheral mononuclear cells from subjects with prediabetes. A randomized controlled trial. (2015) (71)
Apoptosis of skeletal and cardiac muscles and physical exercise (1997) (71)
Handbook on immunosenescence : basic understanding and clinical applications (2009) (71)
The genetics of human longevity: an intricacy of genes, environment, culture and microbiome (2017) (69)
Human longevity and 11p15.5: a study in 1321 centenarians (2009) (69)
Autogeneic but not allogeneic earthworm effector coelomocytes kill the mammalian tumor cell target K562. (1995) (69)
Mitochondrial DNA Backgrounds Might Modulate Diabetes Complications Rather than T2DM as a Whole (2011) (69)
Gut microbiota and osteoarthritis management: An expert consensus of the European society for clinical and economic aspects of osteoporosis, osteoarthritis and musculoskeletal diseases (ESCEO) (2019) (69)
Male/female ratio in centenarians: a possible role played by population genetic structure (2002) (69)
Genomic Instability and Aging (1992) (69)
Massive activation of immune cells with an intact T cell repertoire in acute human immunodeficiency virus syndrome. (1995) (69)
Mutant factor V (Arg506Gln) in healthy centenarians (1996) (69)
Invertebrate and Vertebrate Immune Cells Express Pro-opiomelanocortin (POMC) mRNA (1995) (69)
Spontaneous and mitomycin-C-induced micronuclei in human lymphocytes exposed to extremely low frequency pulsed magnetic fields. (1991) (68)
Mitochondria hyperfusion and elevated autophagic activity are key mechanisms for cellular bioenergetic preservation in centenarians (2014) (68)
Oral zinc supplementation in Down's syndrome: restoration of thymic endocrine activity and of some immune defects. (2008) (68)
Inflammaging 2018: An update and a model. (2018) (68)
Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis (2004) (67)
Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population (2010) (67)
Age‐related changes of the 3′APOB‐VNTR genotype pool in ageing cohorts (1998) (67)
Lamins are rapamycin targets that impact human longevity: a study in centenarians (2014) (66)
Systems biology and longevity: an emerging approach to identify innovative anti-aging targets and strategies. (2010) (66)
Common evolutionary origin of the immune and neuroendocrine systems: from morphological and functional evidence to in silico approaches. (2007) (66)
Human Immunosenescence (2006) (66)
DNA multiallelic systems reveal gene/longevity associations not detected by diallelic systems. The APOB locus (1997) (65)
Hormetic approaches to the treatment of Parkinson's disease: Perspectives and possibilities (2018) (65)
Reprint of: A parallel randomized trial on the effect of a healthful diet on inflammageing and its consequences in European elderly people: Design of the NU-AGE dietary intervention study (2013) (65)
Studies of the relationship between cell proliferation and cell death. II. Early gene expression during concanavalin A-induced proliferation or dexamethasone-induced apoptosis of rat thymocytes. (1992) (64)
Anti-inflammatory effect of ubiquinol-10 on young and senescent endothelial cells via miR-146a modulation. (2013) (64)
Cell‐free DNA as a biomarker of aging (2018) (64)
Aged-related increase of high sensitive Troponin T and its implication in acute myocardial infarction diagnosis of elderly patients (2012) (64)
Association of metabolic syndrome with cognitive function: the role of sex and age. (2008) (64)
Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians (2002) (64)
Thyroid autoimmunity and aging (1998) (63)
Human models of aging and longevity. (2008) (63)
Genetics of Human Longevity Within an Eco-Evolutionary Nature-Nurture Framework (2018) (63)
PON1 is a longevity gene: Results of a meta-analysis (2009) (63)
Inhibition of c-fes expression by an antisense oligomer causes apoptosis of HL60 cells induced to granulocytic differentiation (1993) (62)
Association studies on human mitochondrial DNA: methodological aspects and results in the most common age-related diseases. (2007) (62)
Shotgun Metagenomics of Gut Microbiota in Humans with up to Extreme Longevity and the Increasing Role of Xenobiotic Degradation (2020) (62)
Stress response in the freshwater snail Planorbarius corneus (L.) (Gastropoda, Pulmonata): interaction between CRF, ACTH, and biogenic amines. (1992) (62)
Human longevity within an evolutionary perspective: The peculiar paradigm of a post-reproductive genetics (2008) (61)
Pre-Operative, High-IL-6 Blood Level is a Risk Factor of Post-Operative Delirium Onset in Old Patients (2014) (61)
Age-Related Modifications in Circulating IL-15 Levels in Humans (2005) (61)
Resistance to apoptosis in CTLL-2 cells overexpressing B-Myb is associated with B-Myb-dependent bcl-2 induction. (1999) (61)
Association between the MHC class I gene HFE polymorphisms and longevity: a study in Sicilian population (2002) (61)
p66 shc is highly expressed in fibroblasts from centenarians (2005) (61)
Charting the NF-κB Pathway Interactome Map (2012) (61)
Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: A proof of principle on type 2 diabetes (2013) (60)
Cholesteryl ester transfer protein (CETP) I405V polymorphism and longevity in Italian centenarians (2005) (60)
Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process (2017) (60)
What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians (2002) (60)
Are Nutrition-Related Knowledge and Attitudes Reflected in Lifestyle and Health Among Elderly People? A Study Across Five European Countries (2018) (60)
Immunosupportive therapies in aging (2007) (59)
Role of the pyrin M694V (A2080G) allele in acute myocardial infarction and longevity: a study in the Sicilian population (2006) (59)
CRF provokes the release of norepinephrine by hemocytes of Viviparus ater (Gastropoda, Prosobranchia): further evidence in favour of the evolutionary hypothesis of the mobile immune-brain. (1993) (59)
Age‐dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK‐AGE study (2016) (59)
Chronic antigenic load and apoptosis in immunosenescence. (2005) (59)
Towards a Liquid Self: How Time, Geography, and Life Experiences Reshape the Biological Identity (2014) (59)
Hypertension Is Associated With Intestinal Microbiota Dysbiosis and Inflammation in a Brazilian Population (2020) (59)
A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome accelerate short- and long-term inflammaging? (2020) (58)
Involvement of Ets transcription factors and targets in osteoblast differentiation and matrix mineralization. (2000) (58)
Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics. (2015) (58)
Age-Related Changes of Adaptive and Neuropsychological Features in Persons with Down Syndrome (2014) (58)
The role of IL-1 gene cluster in longevity: a study in Italian population (2003) (58)
T lymphocyte proliferative capability to defined stimuli and costimulatory CD28 pathway is not impaired in healthy centenarians (1997) (57)
Lack of chromosomal aberration and micronucleus induction in human lymphocytes exposed to pulsed magnetic fields. (1994) (57)
The epigenetic landscape of age-related diseases: the geroscience perspective (2017) (57)
The effect of L-carnitine and acetyl-L-carnitine on the disappearance of DNA single-strand breaks in human peripheral blood lymphocytes. (1993) (57)
Effect of the NU-AGE Diet on Cognitive Functioning in Older Adults: A Randomized Controlled Trial (2018) (57)
Cytokines and Evolution: In Vitro Effects of IL-1α, IL-1β, TNF-α and TNF-β on an Ancestral Type of Stress Response (1995) (56)
P53 codon 72 polymorphism and longevity: additional data on centenarians from continental Italy and Sardinia. (1999) (56)
p53 Codon 72 Alleles Influence the Response to Anticancer Drugs in Cells from Aged People by Regulating the Cell Cycle Inhibitor p21WAF1 (2005) (56)
A meta-analysis on age-associated changes in blood DNA methylation: results from an original analysis pipeline for Infinium 450k data (2015) (55)
Gene expression of cytokines and cytokine receptors is modulated by the common variability of the mitochondrial DNA in cybrid cell lines (2006) (55)
Increased circulating Interleukin-18 levels in centenarians with no signs of vascular disease: another paradox of longevity? (2003) (55)
Increased Plin2 Expression in Human Skeletal Muscle Is Associated with Sarcopenia and Muscle Weakness (2013) (55)
Meeting report: mitochondrial DNA and cancer epidemiology. (2007) (55)
The mitochondrial DNA control region shows genetically correlated levels of heteroplasmy in leukocytes of centenarians and their offspring (2007) (55)
Invariant NKT cells contribute to chronic lymphocytic leukemia surveillance and prognosis. (2017) (55)
An APOE haplotype associated with decreased ε4 expression increases the risk of late onset Alzheimer's disease. (2011) (55)
SERUM IMMUNOGLOBULINS AND LYMPHOCYTE SUBPOPULATIONS DERANGEMENT IN TURNER'S SYNDROME (1981) (54)
Stochastic epigenetic mutations (DNA methylation) increase exponentially in human aging and correlate with X chromosome inactivation skewing in females (2015) (54)
Successful immunosenescence and the remodelling of immune responses with ageing. (1996) (54)
TET2 gene expression and 5-hydroxymethylcytosine level in multiple sclerosis peripheral blood cells. (2014) (54)
Plasma concentrations of interleukin-1-beta, interleukin-6 and tumor necrosis factor-alpha, and of their soluble receptors and receptor antagonist in anorexia nervosa (2001) (54)
Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)γ-2 with longevity (2004) (53)
The Impact of Caloric Restriction on the Epigenetic Signatures of Aging (2019) (53)
A new theory on the common evolutionary origin of natural immunity, inflammation and stress response: the invertebrate phagocytic immunocyte as an eye-witness. (1998) (53)
Interleukin-6-174 G > C polymorphism affects the association between IL-6 plasma levels and insulin resistance in type 2 diabetic patients. (2006) (53)
GDF15 Plasma Level Is Inversely Associated With Level of Physical Activity and Correlates With Markers of Inflammation and Muscle Weakness (2020) (52)
Oxidative DNA damage repair and parp 1 and parp 2 expression in Epstein-Barr virus-immortalized B lymphocyte cells from young subjects, old subjects, and centenarians. (2007) (52)
Purification and properties of two lectins from the latex of the euphorbiaceous plants Hura crepitans L. (sand-box tree) and Euphorbia characias L. (Mediterranean spurge). (1983) (52)
A shift to Th0 cytokine production by CD4+ cells in human longevity: Studies on two healthy centenarians (1996) (52)
The unexpected contribution of immunosenescence to the leveling off of cancer incidence and mortality in the oldest old. (2001) (52)
Genetic polymorphisms of Fas (CD95) and FasL (CD178) in human longevity: studies on centenarians (2002) (52)
Microbiomes other than the gut: inflammaging and age-related diseases (2020) (52)
Is chronic inflammation a determinant of blood pressure in the elderly? (2003) (52)
Ageing, longevity, exceptional longevity and related genetic and non genetics markers: panel statement. (2014) (51)
Introduction: the reshaping of the immune system with age. (1995) (51)
Increased Cytokine Production by Peripheral Blood Mononuclear Cells from Healthy Elderly People a (1992) (51)
Presence of immunoreactive corticotropin-releasing hormone and cortisol molecules in invertebrate haemocytes and lower and higher vertebrate thymus (1998) (51)
Transcription factors DNA-binding activity in rat thymocytes undergoing apoptosis after heat-shock or dexamethasone treatment. (1993) (51)
T and B lypmhocyte subpopulations in Down's syndrome. A study on non-institutionalised subjects. (2008) (50)
Identification of miR‐31‐5p, miR‐141‐3p, miR‐200c‐3p, and GLT1 as human liver aging markers sensitive to donor–recipient age‐mismatch in transplants (2016) (50)
The −308G/A polymorphism of TNF‐α influences immunological parameters in old subjects affected by infectious diseases (2005) (50)
Nutrition and Inflammation: Are Centenarians Similar to Individuals on Calorie-Restricted Diets? (2018) (50)
Steroid Regulation of Cytokines. Relevance for TH1‐to‐TH2 Shift? a (1994) (49)
Involvement of ornithine decarboxylase and polyamines in glucocorticoid-induced apoptosis of rat thymocytes. (1995) (49)
Resistance to apoptosis of HCW‐2 cells can be overcome by curcumin‐ or vincristine‐induced mitotic catastrophe (2006) (49)
Inferring chronological age from DNA methylation patterns of human teeth. (2016) (49)
Karyotype instability and anchorage-independent growth in telomerase-immortalized fibroblasts from two centenarian individuals. (2003) (49)
The impact of mitochondrial DNA on human lifespan: A view from studies on centenarians (2008) (49)
Naïve and memory CD8 T cell pool homeostasis in advanced aging: impact of age and of antigen-specific responses to cytomegalovirus (2013) (49)
Adenosine A3 receptors and viability of astrocytes (1998) (49)
Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing (2018) (49)
Hormone replacement therapy enhances IGF-1 signaling in skeletal muscle by diminishing miR-182 and miR-223 expressions: a study on postmenopausal monozygotic twin pairs (2014) (48)
Differential modulation of invertebrate hemocyte motility by CRF, ACTH, and its fragments (1994) (48)
Age‐dependent skewing of X chromosome inactivation appears delayed in centenarians’ offspring. Is there a role for allelic imbalance in Healthy Aging and Longevity? (2011) (48)
Remodelling of biological parameters during human ageing: evidence for complex regulation in longevity and in type 2 diabetes (2013) (48)
p53 variants predisposing to cancer are present in healthy centenarians. (1999) (48)
Effects of Donepezil,Galantamine and Rivastigmine in 938 Italian Patients with Alzheimer’s Disease (2010) (47)
Is polyamine decrease a common feature of apoptosis? Evidence from gamma rays- and heat shock-induced cell death. (1995) (47)
The allele (A)-110 in the promoter region of the HSP70-1 gene is unfavorable to longevity in women (2004) (47)
Aging, Longevity, and Cancer: Studies in Down's Syndrome and Centenarians a (1991) (47)
Centenarians’ offspring as a model of healthy aging: a reappraisal of the data on Italian subjects and a comprehensive overview (2016) (47)
The Study of APOA1, APOC3 and APOA4 Variability in Healthy Ageing People Reveals Another Paradox   in the Oldest Old Subjects (2003) (47)
One-year Mediterranean diet promotes epigenetic rejuvenation with country- and sex-specific effects: a pilot study from the NU-AGE project (2020) (47)
50 Hz AC sinusoidal electric fields do not exert genotoxic effects (micronucleus formation) in human lymphocytes. (1993) (47)
Micronucleus frequency and cell proliferation in human lymphocytes exposed to 50 Hz sinusoidal magnetic fields. (1999) (46)
Tumor necrosis factor-alpha gene −308G>A polymorphism is associated with ST-elevation myocardial infarction and with high plasma levels of biochemical ischemia markers (2005) (46)
The Paradoxes of Longevity (1999) (46)
DNA repair after gamma irradiation in lymphocytes exposed to low-frequency pulsed electromagnetic fields. (1989) (46)
Mismatch repair system and aging: microsatellite instability in peripheral blood cells from differently aged participants. (2005) (46)
Studies of the relationship between cell proliferation and cell death. III. AP-1 DNA-binding activity during concanavalin A-induced proliferation or dexamethasone-induced apoptosis of rat thymocytes. (1993) (46)
Sex Differences in Genetic Associations With Longevity (2018) (46)
C3‐Fullero‐tris‐methanodicarboxylic acid protects epithelial cells from radiation‐induced anoikia by influencing cell adhesion ability (1999) (45)
Report from the second cytomegalovirus and immunosenescence workshop (2011) (45)
Gut Microbiome in Down Syndrome (2014) (45)
Senescence associated macrophages and “macroph-aging”: are they pieces of the same puzzle? (2016) (45)
MARK-AGE standard operating procedures (SOPs): A successful effort (2015) (45)
Epigenome-wide association study in hepatocellular carcinoma: Identification of stochastic epigenetic mutations through an innovative statistical approach (2017) (45)
Thyroid autoimmunity and ageing. (1995) (44)
Numerical and functional alterations of circulating gammadelta T lymphocytes in aged people and centenarians. (2002) (44)
Y Chromosome Binary Markers to Study the High Prevalence of Males in Sardinian Centenarians and the Genetic Structure of the Sardinian Population (2001) (44)
p53 codon 72 genotype affects apoptosis by cytosine arabinoside in blood leukocytes. (2002) (44)
The variability of the mitochondrial genome in human aging: a key for life and death? (2002) (44)
Enhanced DNA repair in lymphocytes of Down syndrome patients: the influence of zinc nutritional supplementation. (1993) (44)
Plasma N-Glycome Signature of Down Syndrome. (2015) (44)
Analysis of Population Substructure in Two Sympatric Populations of Gran Chaco, Argentina (2013) (44)
Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework (2020) (44)
Circulating miR-21, miR-146a and Fas ligand respond to postmenopausal estrogen-based hormone replacement therapy – A study with monozygotic twin pairs (2014) (44)
Decrease in mitochondrial energy coupling by thyroid hormones: a physiological effect rather than a pathological hyperthyroidism consequence (1998) (43)
Reduced susceptibility to peroxidation of erythrocyte plasma membranes from centenarians (2002) (43)
N-glycan profiles as tools in diagnosis of hepatocellular carcinoma and prediction of healthy human ageing (2009) (43)
Measuring the genetic influence in modulating the human life span: gene–environment interaction and the sex-specific genetic effect (2004) (43)
Markers of inflammation, Vitamin E and peripheral nervous system function The InCHIANTI study (2006) (43)
Studies on the relationship between cell proliferation and cell death: opposite patterns of SGP-2 and ornithine decarboxylase mRNA accumulation in PHA-stimulated human lymphocytes. (1991) (43)
Postoperative Delirium after elective and emergency surgery: analysis and checking of risk factors. A study protocol (2005) (43)
A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms (2006) (43)
Structural Brain Abnormalities in Successfully Treated HIV Infection: Associations With Disease and Cerebrospinal Fluid Biomarkers (2017) (42)
Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population: A Cross-Sectional Study in Six European Countries (2016) (42)
Somatic Point Mutations in mtDNA Control Region Are Influenced by Genetic Background and Associated with Healthy Aging: A GEHA Study (2010) (42)
Association of p53 polymorphisms and colorectal cancer: modulation of risk and progression. (2009) (42)
The “immune-mobile brain”: Evolutionary evidence (1991) (42)
Activity of mannose‐binding lectin in centenarians (2012) (42)
Association between the HFE mutations and unsuccessful ageing: a study in Alzheimer's disease patients from Northern Italy (2003) (42)
Genetic epidemiologic studies on age-specified traits (2000) (42)
Apoptosis remodeling in immunosenescence: implications for strategies to delay ageing. (2007) (42)
Evidence for an Association between the SRD5A2 (Type II Steroid 5α-Reductase) Locus and Prostate Cancer in Italian Patients (2002) (42)
Quantifying the relevance of different mediators in the human immune cell network (2004) (42)
LL-paraoxonase genotype is associated with a more severe degree of homeostasis model assessment IR in healthy subjects. (2002) (41)
Earthworm coelomocytes in vitro: cellular features and "granuloma" formation during cytotoxic activity against the mammalian tumor cell target K562. (1996) (41)
Growth properties and growth factor responsiveness in skin fibroblasts from centenarians. (1998) (41)
A Mediterranean-like dietary pattern with vitamin D3 (10 µg/d) supplements reduced the rate of bone loss in older Europeans with osteoporosis at baseline: results of a 1-y randomized controlled trial (2018) (41)
Mitochondrial mass and membrane potential in coelomocytes from the earthworm Eisenia foetida: studies with fluorescent probes in single intact cells. (1995) (41)
Mitochondria, immunosenescence and inflammaging: a role for mitokines? (2020) (41)
Paraoxonase 1: genetics and activities during aging. (2008) (41)
COVID-19 mortality in Lombardy: the vulnerability of the oldest old and the resilience of male centenarians (2020) (41)
Inflammaging, hormesis and the rationale for anti-aging strategies (2020) (41)
A polymorphism of the YTHDF2 gene (1p35) located in an Alu-rich genomic domain is associated with human longevity. (2006) (40)
Anti-beta 2 glycoprotein I antibodies in centenarians (2004) (40)
Complex interplay between neutral and adaptive evolution shaped differential genomic background and disease susceptibility along the Italian peninsula (2016) (39)
Ecoimmunology: is there any room for the neuroendocrine system? (2008) (39)
Enhancing effect of low frequency pulsed electromagnetic fields on lectin-induced human lymphocyte proliferation (1986) (39)
Paraoxonase activity and genotype predispose to successful aging. (2006) (38)
Poly(ADP-ribosyl)ation is involved in the epigenetic control of TET1 gene transcription (2014) (38)
The conundrum of human immune system “senescence” (2020) (38)
Genetic polymorphisms of inflammatory cytokines and myocardial infarction in the elderly (2006) (38)
A parallel randomized trial on the effect of a healthful diet on inflammageing and its consequences in European elderly people: Design of the NU-AGE dietary intervention study (2013) (38)
mtDNA mutations in human aging and longevity: Controversies and new perspectives opened by high-throughput technologies (2014) (38)
Polymorphisms of drug-metabolizing enzymes in healthy nonagenarians and centenarians: difference at GSTT1 locus. (2001) (37)
Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians (2019) (37)
The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans (2017) (37)
Association between the HFE mutations and longevity: a study in Sardinian population (2003) (37)
DNA repair after gamma radiation and superoxide dismutase activity in lymphocytes from subjects of far advanced age. (1982) (37)
Colorectal cancer microenvironment: among nutrition, gut microbiota, inflammation and epigenetics. (2012) (37)
Toxicity ofMomordica charantia lectin and inhibitor for human normal and leukaemic lymphocytes (1980) (37)
Systems medicine of inflammaging (2015) (37)
Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population (2009) (37)
Chagas disease: serological and electrocardiographic studies in Wichi and Creole communities of Misión Nueva Pompeya, Chaco, Argentina. (2010) (36)
Association between the HLA-DR alleles and longevity: a study in Sardinian population (2003) (36)
Age-related DNA methylation changes are sex-specific: a comprehensive assessment (2020) (36)
Modeling the in vitro 20S proteasome activity: the effect of PA28-alphabeta and of the sequence and length of polypeptides on the degradation kinetics. (2008) (36)
Studies on immunoproteasome in human liver. Part I: absence in fetuses, presence in normal subjects, and increased levels in chronic active hepatitis and cirrhosis. (2010) (36)
An allele of HRAS1 3'variable number of tandem repeats is a frailty allele: implication for an evolutionarily-conserved pathway involved in longevity. (2002) (35)
Health status and 6 years survival of 552 90+ Italian sib-ships recruited within the EU Project GEHA (GEnetics of Healthy Ageing) (2014) (35)
Impact of diet and nutraceutical supplementation on inflammation in elderly people. Results from the RISTOMED study, an open-label randomized control trial. (2016) (35)
3-Aminobenzamide protects cells from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion. (1995) (35)
Correction: Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of Lipids, Amino Acids, and Gut Microbiota Metabolism (2013) (35)
Antisense inhibition of c-fes proto-oncogene blocks PMA-induced macrophage differentiation in HL60 and in FDC-P1/MAC-11 cells. (1997) (34)
Immune parameters identify Italian centenarians with a longer five-year survival independent of their health and functional status (2014) (34)
Age-related increase of mitomycin C-induced micronuclei in lymphocytes from Down's syndrome subjects. (1990) (34)
A genetic-demographic approach reveals male-specific association between survival and tumor necrosis factor (A/G)-308 polymorphism. (2008) (34)
Cognitive status in the oldest old and centenarians: a condition crucial for quality of life methodologically difficult to assess (2017) (34)
Lamin A involvement in ageing processes (2020) (34)
A cluster analysis to define human aging phenotypes (2007) (34)
2-deoxy-d-ribose induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. (2008) (34)
Immunoproteasome in cancer and neuropathologies: a new therapeutic target? (2012) (34)
Epigenetic Variability across Human Populations: A Focus on DNA Methylation Profiles of the KRTCAP3, MAD1L1 and BRSK2 Genes (2016) (34)
Accelerated bio‐cognitive aging in Down syndrome: State of the art and possible deceleration strategies (2019) (33)
Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study (2016) (33)
Enhancing effect of lithium and potassium ions on lectin-induced lymphocyte proliferation in aging and Down's syndrome subjects. (1983) (33)
c-fos/c-jun expression and AP-1 activation in skin fibroblasts from centenarians. (1996) (33)
Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly population (2020) (33)
Congenital disorders sharing oxidative stress and cancer proneness as phenotypic hallmarks: prospects for joint research in pharmacology. (1998) (33)
Molecular variation of human HSP90α and HSP90β genes in Caucasians (2003) (33)
Opposite Role of Pro‐Inflammatory Alleles in Acute Myocardial Infarction and Longevity (2006) (33)
Changes in Dietary Intake and Adherence to the NU-AGE Diet Following a One-Year Dietary Intervention among European Older Adults—Results of the NU-AGE Randomized Trial (2018) (33)
Alterations of the capping phenomenon on lymphocytes from aged and Down's syndrome subjects. (1984) (33)
Immunoproteasome expression is induced in mesial temporal lobe epilepsy. (2011) (33)
Terminal differentiation of T cells is strongly associated with CMV infection and increased in HIV-positive individuals on ART and lifestyle matched controls (2017) (33)
The epigenetic side of human adaptation: hypotheses, evidences and theories (2015) (33)
Space/Population and Time/Age in DNA methylation variability in humans: a study on IGF2/H19 locus in different Italian populations and in mono- and di-zygotic twins of different age (2012) (32)
Heat shock response by EBV-immortalized B-lymphocytes from centenarians and control subjects: a model to study the relevance of stress response in longevity (2004) (32)
Purines and cell death (1996) (32)
High-Resolution Quantitative Metabolome Analysis of Urine by Automated Flow Injection NMR (2013) (32)
Genes associated with Type 2 Diabetes and vascular complications (2018) (32)
Identification of novel plasma glycosylation-associated markers of aging (2016) (32)
The Dual Role of the Pervasive “Fattish” Tissue Remodeling With Age (2019) (32)
The methylation of nuclear and mitochondrial DNA in ageing phenotypes and longevity (2017) (32)
Pre-analytical stability of the plasma proteomes based on the storage temperature (2013) (32)
Role of TLR4 Receptor Polymorphisms in Boutonneuse Fever (2005) (32)
Molecular Aging of Human Liver: An Epigenetic/Transcriptomic Signature (2018) (32)
Evolution of neuroendocrine thymus: studies on POMC-derived peptides, cytokines and apoptosis in lower and higher vertebrates (1997) (32)
Centenarians as extreme phenotypes: An ecological perspective to get insight into the relationship between the genetics of longevity and age-associated diseases (2017) (32)
Life Expectancy in the Immune Recovery Era: The Evolving Scenario of the HIV Epidemic in Northern Italy (2014) (31)
Age-dependent remodeling of rat thymus. Morphological and cytofluorimetric analysis from birth up to one year of age. (1998) (31)
The Aging Thyroid: A Reappraisal Within the Geroscience Integrated Perspective. (2019) (31)
Transmission from centenarians to their offspring of mtDNA heteroplasmy revealed by ultra-deep sequencing (2014) (31)
Immune therapy for age-related diseases. (2009) (31)
Cell death protection by 3-aminobenzamide and other poly(ADP-ribose)polymerase inhibitors: different effects on human natural killer and lymphokine activated killer cell activities. (1994) (30)
Phenotypic characteristics and tendency to apoptosis of peripheral blood mononuclear cells from HIV+ long term non progressors (1997) (30)
The peculiar aging of human liver: A geroscience perspective within transplant context (2019) (30)
Role of polymorphisms of CC-chemokine receptor-5 gene in acute myocardial infarction and biological implications for longevity (2008) (30)
Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project (2017) (30)
Complex patterns of gene expression in human T cells during in vivo aging. (2010) (30)
Age-Related DNA Methylation Changes: Potential Impact on Skeletal Muscle Aging in Humans (2019) (30)
Does the longevity of one or both parents influence the health status of their offspring? (2013) (30)
Metabolic syndrome in the offspring of centenarians: focus on prevalence, components, and adipokines (2013) (30)
Apoptosis-resistant phenotype in HL-60-derived cells HCW-2 is related to changes in expression of stress-induced proteins that impact on redox status and mitochondrial metabolism (2003) (30)
Analysis of HLA-DRB1,DQA1,DQB1 haplotypes in Sardinian centenarians (2008) (30)
In vitro IL-6 production by EBV-immortalized B lymphocytes from young and elderly people genotyped for −174 C/G polymorphism in IL-6 gene: a model to study the genetic basis of inflamm-aging (2003) (30)
Pattern of care and effectiveness of treatment for glioblastoma patients in the real world: Results from a prospective population-based registry. Could survival differ in a high-volume center? (2014) (30)
Distinct biological ages of organs and systems identified from a multi-omics study. (2022) (29)
The p53 codon 72 (Arg72Pro) polymorphism is associated with the degree of insulin resistance in type 2 diabetic subjects: a cross-sectional study (2013) (29)
Inflammation and Life-Span (2005) (29)
TP53 codon 72 polymorphism affects accumulation of mtDNA damage in human cells (2012) (29)
Proteomics in aging research: A roadmap to clinical, translational research (2021) (29)
Musculoskeletal system in the old age and the demand for healthy ageing biomarkers (2013) (28)
Association between the interleukin-1 beta polymorphisms and Alzheimer's disease: A systematic review and meta-analysis (2008) (28)
C4, BF, C3 allele distribution and complement activity in healthy aged people and centenarians. (1999) (28)
Polyamine depletion protects HL-60 cells from 2-deoxy-D-ribose-induced apoptosis. (1998) (28)
Genomic instability and aging. Studies in centenarians (successful aging) and in patients with Down's syndrome (accelerated aging). (1992) (28)
Does a retrograde response in human aging and longevity exist? (2000) (28)
Senescence, Immortalization, and Apoptosis (1992) (28)
Down syndrome, accelerated aging and immunosenescence (2020) (28)
Gender-specific association of body composition with inflammatory and adipose-related markers in healthy elderly Europeans from the NU-AGE study (2019) (28)
Cell Proliferation and Cell Death in Immunosenescence a (1992) (28)
MARK-AGE population: From the human model to new insights (2015) (28)
Inhibition of proteasome function prevents thymocyte apoptosis: involvement of ornithine decarboxylase. (1998) (28)
Centenarians as a 21st century healthy aging model: A legacy of humanity and the need for a world-wide consortium (WWC100+) (2017) (28)
Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer’s disease in comparison with healthy aging (2020) (28)
Calcium metabolism and vitamin D in the extreme longevity (2008) (27)
Heterogeneity of Thyroid Function and Impact of Peripheral Thyroxine Deiodination in Centenarians and Semi-Supercentenarians: Association With Functional Status and Mortality. (2018) (27)
Identification of Pre-frailty Sub-Phenotypes in Elderly Using Metabolomics (2019) (27)
Evidence for the presence of immunoreactive POMC-derived peptides and cytokines in the thymus of the goldfish (Carassius c. auratus) (1995) (27)
NK Cell Activity and T‐Lymphocyte Proliferation in Healthy Centenarians a (1992) (27)
Associations between Pro- and Anti-Inflammatory Gastro-Intestinal Microbiota, Diet, and Cognitive Functioning in Dutch Healthy Older Adults: The NU-AGE Study (2020) (27)
Lack of selective Vβ deletion in CD4+ or CD8+ T lymphocytes and functional integrity of T‐cell repertoire during acute HIV syndrome (1995) (26)
Association between the HLA-A2 allele and Alzheimer disease. (2006) (26)
Age-dependent changes in the susceptibility to apoptosis of peripheral blood CD4+ and CD8+ T lymphocytes with virgin or memory phenotype (2003) (26)
Genome-wide DNA methylation analysis in blood cells from patients with Werner syndrome (2017) (26)
Integrating Omics data for signaling pathways, interactome reconstruction, and functional analysis. (2011) (26)
Dissecting the Pre-Columbian Genomic Ancestry of Native Americans along the Andes–Amazonia Divide (2019) (26)
Neutral endopeptidase-24.11 (NEP) activity in human fibroblasts during development and ageing (1998) (26)
2-deoxy-d-ribose-induced apoptosis in HL-60 cells is associated with the cell cycle progression by spermidine. (1999) (25)
Recovery of human lymphocytes damaged with gamma-radiation or enzymatically produced oxygen radicals: different effects of poly(ADP-ribosyl)polymerase inhibitors. (1990) (25)
Whole-genome sequencing analysis of semi-supercentenarians (2021) (25)
Demographic, genetic and phenotypic characteristics of centenarians in Italy: Focus on gender differences (2017) (25)
Cytogenetic effects induced by extremely low frequency pulsed magnetic fields in lymphocytes from Turner's syndrome subjects (1997) (25)
Evidence for dissimilar mechanisms of enhancement of inorganic and organic hydroperoxide cytotoxicity by L-histidine. (1995) (25)
Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER‐2/neu transgenic mice (2002) (25)
Resistance to apoptosis in Fanconi's anaemia (1997) (25)
Differential expression of perilipin 2 and 5 in human skeletal muscle during aging and their association with atrophy-related genes (2015) (25)
The nucleolar size is associated to the methylation status of ribosomal DNA in breast carcinomas (2014) (25)
Exposure to 100 Hz pulsed magnetic fields increases micronucleus frequency and cell proliferation in human lymphocytes (1997) (24)
Cloning of differentially expressed genes in skin fibroblasts from centenarians (2004) (24)
Cytoskeleton alterations of erythrocytes from patients with Fanconi's anemia (2000) (24)
Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains (2021) (24)
The preventive strategy for pandemics in the elderly is to collect in advance samples & data to counteract chronic inflammation (inflammaging) (2020) (24)
Sister chromatid exchanges and DNA repair capability in sanitary workers exposed to ethylene oxide: evaluation of the dose-effect relationship. (1987) (24)
Effect of zinc ions on apoptosis in PBMCs from healthy aged subjects (2006) (24)
Purification and partial characterization of a mitogenic lectin from Vicia sativa. (1979) (24)
The Human Body as a Super Network: Digital Methods to Analyze the Propagation of Aging (2020) (24)
Healthy ageing in 2016: Obesity in geroscience — is cellular senescence the culprit? (2017) (24)
Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans (2020) (24)
A stochastic model for CD8(+)T cell dynamics in human immunosenescence: implications for survival and longevity. (2001) (24)
Evidence for reduction of pro-atherosclerotic properties in platelets from healthy centenarians (2003) (24)
Prostaglandin and thromboxane biosynthesis in isolated platelet-free human monocytes. I. A modified procedure for the characterization of the prostaglandin spectrum produced by resting and activated monocytes. (1985) (23)
A cytofluorimetric study of T lymphocyte subsets in rat lymphoid tissues (thymus, lymph nodes) and peripheral blood: a continuous remodelling during the first year of life (2000) (23)
Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study (2019) (23)
The neuro-immunological interface in an evolutionary perspective: the dynamic relationship between effector and recognition systems. (1998) (23)
Increase of homozygosity in centenarians revealed by a new inter-Alu PCR technique (2001) (23)
Effect of low frequency low energy pulsing electromagnetic fields on mice injected with cyclophosphamide. (1991) (23)
X-chromosome-linked miR548am-5p is a key regulator of sex disparity in the susceptibility to mitochondria-mediated apoptosis (2019) (23)
Recovery from 6-month spaceflight at the International Space Station: muscle-related stress into a proinflammatory setting (2019) (23)
Fine Dissection of Human Mitochondrial DNA Haplogroup HV Lineages Reveals Paleolithic Signatures from European Glacial Refugia (2015) (23)
Masticatory dysfunction is associated with osteoporosis in older men. (2007) (22)
Brain aging and garbage cleaning (2020) (22)
Literature review in support of adjuvanticity/immunogenicity assessment of proteins (2019) (22)
The BB-paraoxonase genotype is associated with impaired brachial reactivity after acute hypertriglyceridemia in healthy subjects. (2001) (22)
The challenges in moving from ageing to successful longevity. (2013) (22)
Metabolic gene polymorphisms and p53 mutations in healthy centenarians and younger controls (2003) (22)
A centenarian-only approach for assessing gene–gene interaction in human longevity (2002) (22)
Stress, inflammation and natural immunity in the aging process: a new theory (1997) (22)
Different antioxidant profiles in Italian centenarians: the Sardinian peculiarity (2007) (22)
Age‐related alterations in muscle architecture are a signature of sarcopenia: the ultrasound sarcopenia index (2021) (21)
Genes of human longevity: an endless quest? (2013) (21)
Conserved and species-specific molecular denominators in mammalian skeletal muscle aging (2017) (21)
Presence and role of cytokines and growth factors in invertebrates (1996) (21)
Maturation of the immkune response in vitro. Focal fluctuation and changes in affinity of anti-beta-D-galactosidase activating antibody. (1972) (21)
A novel sampling design to explore gene-longevity associations: the ECHA study (2008) (20)
Age dependent impact of LMP polymorphisms on TNFα-induced apoptosis in human peripheral blood mononuclear cells (2002) (20)
Allele frequencies of +874T→A single nucleotide polymorphism at the first intron of IFN-γ gene in Alzheimer’s disease patients (2003) (20)
Immunological parameters in aging: studies on natural immunomodulatory and immunoprotective substances. (1990) (20)
Effect of low frequency low energy pulsing electromagnetic field (PEMF) on X-ray-irradiated mice. (1989) (20)
Lifelong maintenance of composition, function and cellular/subcellular distribution of proteasomes in human liver (2014) (20)
In vitro hypersensitivity to oxygen of Fanconi anemia (FA) cells is linked to ex vivo evidence for oxidative stress in FA homozygotes and heterozygotes. (1997) (20)
The Contextualized Genetics of Human Longevity: JACC Focus Seminar. (2020) (20)
A review of the biomedical innovations for healthy longevity (2017) (20)
Models for preclinical studies in aging-related disorders: One is not for all (2015) (20)
C Polymorphism of Interleukin 6 Gene Promoter Affects Interleukin 6 Serum Level in Patients with Colorectal Cancer (2003) (19)
Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement (2017) (19)
Chronic renal impairment and DDAH2-1151 A/C polymorphism determine ADMA levels in type 2 diabetic subjects. (2013) (19)
Lifelong calorie restriction affects indicators of colonic health in aging C57Bl/6J mice. (2018) (19)
Impact of demography and population dynamics on the genetic architecture of human longevity (2018) (19)
Age‐Dependent Effects of in Vitro Radiofrequency Exposure (Mobile Phone) on CD95+ T Helper Human Lymphocytes (2006) (19)
Influence of f-MLP, ACTH(1–24) and CRH on in vitro Chemotaxis of Monocytes from Centenarians (2008) (19)
The Impact of Phenocopy on the Genetic Analysis of Complex Traits (2009) (19)
Ethical aspects of aging research (2011) (19)
Study of the Association with −330T/G IL-2 in a Population of Centenarians from Centre and South Italy (2005) (19)
Suggestions from Geroscience for the Genetics of Age-Related Diseases (2016) (19)
Replication studies in longevity: puzzling findings in Danish centenarians at the 3'APOB-VNTR locus. (2001) (19)
GDF15, an emerging key player in human aging (2022) (19)
Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients. (2009) (18)
The MALVA (MAntova LongeVA) study: an investigation on people 98 years of age and over in a province of Northern Italy (2003) (18)
Depression of homograft rejection and graft-versus-host reactivity following 7,12-dimethylbenz(a)anthracene exposure in the rat. (1971) (17)
The complex relationship between Immunosenescence and Inflammaging: Special issue on the New Biomedical Perspectives (2020) (17)
Evolution, immune responses and stress: studies on molluscan cells. (1992) (17)
Muscle‐specific Perilipin2 down‐regulation affects lipid metabolism and induces myofiber hypertrophy (2018) (17)
Risk profiles in type 2 diabetes (metabolic syndrome): integration of IL-10 polymorphisms and laboratory parameters to identify vascular damages related complications. (2010) (16)
D-ribose inhibits DNA repair synthesis in human lymphocytes. (1986) (16)
Actin cytoskeleton as a target for 2-chloro adenosine: evidence for induction of apoptosis in C2C12 myoblastic cells. (1997) (16)
Human natural killer cytotoxic activity is not affected by in vitro exposure to 50-Hz sinusoidal magnetic fields. (1995) (16)
Microbiome in Blood Samples From the General Population Recruited in the MARK-AGE Project: A Pilot Study (2021) (16)
High Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid (2017) (16)
Presence of a functional vitamin D receptor does not correlate with vitamin D3 phenotypic effects in myeloid differentiation (1997) (16)
A logistic regression model for measuring gene–longevity associations (2001) (16)
Immunosuppressive activity of Tamm-Horsfall glycoprotein oligosaccharides: effect of removal of outer sugars and conjugation with a protein carrier. (1991) (16)
HLA Antigens and Aging a (1992) (16)
Long telomeres and well preserved proliferative vigor in cells from centenarians: A contribution to longevity? (1999) (16)
Dietary Fibre May Mitigate Sarcopenia Risk: Findings from the NU-AGE Cohort of Older European Adults (2020) (16)
High Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid (2017) (16)
DNA Hydroxymethylation Levels Are Altered in Blood Cells From Down Syndrome Persons Enrolled in the MARK-AGE Project (2017) (16)
Mitogenic and haemagglutinating properties of a lectinpurified from Hura crepitans seeds. (1980) (16)
IMMUNOSUPPRESSION BY PHENYTOIN (1976) (16)
Charting the NF-kB pathway interactome map (2010) (16)
Evidences of +896 A/G TLR4 Polymorphism as an Indicative of Prevalence of Complications in T2DM Patients (2014) (15)
'Immunogenetics of Aging': report on the activities of the 15th International HLA and Immunogenetics Working Group and 15th International HLA and Immunogenetics Workshop. (2011) (15)
AGE-RELATED IMBALANCE OF VIRGIN (CD45RA+) AND MEMORY (CD45R0+) CELLS BETWEEN CD4+ AND CD8+ LYMPHOCYTES-T IN HUMANS - A STUDY FROM NEWBORNS TO CENTENARIANS (1992) (15)
The Onset of Type 2 Diabetes: Proposal for a Multi-Scale Model (2013) (15)
The ‘COmorBidity in Relation to AIDS’ (COBRA) cohort: Design, methods and participant characteristics (2018) (15)
Genetics of neurodegenerative disorders. (2003) (15)
BRCA1 Gene Sequence Variation in Centenarians (2001) (15)
Fighting Sarcopenia in Ageing European Adults: The Importance of the Amount and Source of Dietary Proteins (2020) (15)
Epigenetic up-regulation of ribosome biogenesis and more aggressive phenotype triggered by the lack of the histone demethylase JHDM1B in mammary epithelial cells (2017) (15)
Reduced Expression Levels of the Senescence Biomarker Clusterin/Apolipoprotein J in Lymphocytes from Healthy Centenarians (2006) (15)
Short Telomere Length Is Related to Limitations in Physical Function in Elderly European Adults (2018) (15)
Inflammaging in Endemic Areas for Infectious Diseases (2020) (15)
Exposure to low-frequency pulsed electromagnetic fields increases mitogen- induced lymphocyte proliferation in Down’s syndrome (1991) (15)
Biology of ageing. (2000) (15)
50 Hz sinusoidal magnetic fields do not affect human lymphocyte activation and proliferation in vitro (2004) (15)
p66(Shc) gene has a pro-apoptotic role in human cell lines and it is activated by a p53-independent pathway. (2006) (15)
Influence of endorphins on the migration of molluscan hemocytes (1994) (15)
Apoptotic features of peripheral blood granulocytes and monocytes during primary, acute HIV infection. (1999) (15)
Microplate enzyme-linked immunosorbent assay in the study of the structural relationship between myosin light chains. (1979) (15)
Chronic antigenic stress, immunosenescence and human survivorship over the 3 last centuries: heuristic value of a mathematical model (2003) (14)
Oxidative stress, poly(ADP)ribosylation and aging: in vitro studies on lymphocytes from normal and Down's syndrome subjects of different age and from patients with Alzheimer's dementia. (1990) (14)
Population-specific association of genes for telomere-associated proteins with longevity in an Italian population (2015) (14)
Variations at the H-strand replication origins of mitochondrial DNA and mitochondrial DNA content in the blood of type 2 diabetes patients. (2009) (14)
Defective self-recognition in subjects of far-advanced age. (1983) (14)
The PON1192RR genotype is associated with a higher prevalence of arterial hypertension (2006) (14)
Aberrant methylation patterns in colorectal cancer: a meta-analysis (2017) (14)
Slug/β-catenin-dependent proinflammatory phenotype in hypoxic breast cancer stem cells. (2013) (14)
Fetal thymic differentiation in Down's syndrome. (1989) (14)
Protection against Tetanus and Diphtheria in Europe: The impact of age, gender and country of origin based on data from the MARK-AGE Study (2017) (14)
Interference between DNA binding activities of AP-1 and GR transcription factors in rat thymocytes undergoing dexamethasone-induced apoptosis. (1996) (13)
Spontaneous and mitomycin-C-induced micronuclei in lymphocytes from subjects affected by Turner's syndrome. (1996) (13)
Cellular resistance to homocysteine: a key for longevity. (2000) (13)
Involvement of CD45 in dexamethasone- and heat shock-induced apoptosis of rat thymocytes. (1995) (13)
Tracing Behçet's disease origins along the Silk Road: an anthropological evolutionary genetics perspective. (2015) (13)
The adapter protein CD2AP binds to p53 protein in the cytoplasm and can discriminate its polymorphic variants P72R. (2015) (13)
Presence of immunoreactive pro-opiomelanocortin-derived peptides and cytokines in the thymus of an anuran amphibian (Rana esculenta). (1995) (13)
Neuroendocrine Modulation of the Immune System (1996) (13)
An Inflammatory Clock Predicts Multi-morbidity, Immunosenescence and Cardiovascular Aging in Humans (2019) (13)
Quality control data of physiological and immunological biomarkers measured in serum and plasma (2015) (13)
Production of antibodies to amanitins as the basis for their radioimmunoassay (1975) (13)
A geroscience approach for Parkinson’s disease: Conceptual framework and design of PROPAG-AGEING project (2020) (12)
The Pro/Pro genotype of the p53 codon 72 polymorphism modulates PAI-1 plasma levels in ageing (2009) (12)
LAK activity is inducible in blood mononuclear cells from human fetus. (1990) (12)
Beneficial Effects of Elderly Tailored Mediterranean Diet on the Proteasomal Proteolysis (2018) (12)
DNA repair in lymphocytes from humans and rats with chronic iron overload. (1988) (12)
Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells (2018) (12)
Cross-Sectional Analysis of the Correlation Between Daily Nutrient Intake Assessed by 7-Day Food Records and Biomarkers of Dietary Intake Among Participants of the NU-AGE Study (2018) (12)
SGP‐2, Apoptosis, and Aging a (1992) (12)
Memory and Selectivity in Evolving Scale-Free Immune Networks (2003) (11)
A meta-analysis of brain DNA methylation across sex, age and Alzheimer's disease points for accelerated epigenetic aging in neurodegeneration (2020) (11)
Phylogeny of the neuroendocrine-immune system: Fish and shellfish as model systems for social interaction stress research in humans (1993) (11)
Alpha1-antitrypsin heterozygosity plays a positive role in attainment of longevity (2007) (11)
Early downregulation of hsa-miR-144-3p in serum from drug-naïve Parkinson’s disease patients (2022) (11)
The Use of Non-Variant Sites to Improve the Clinical Assessment of Whole-Genome Sequence Data (2015) (11)
The validation of exceptional male longevity in Sardinia (2007) (11)
Cytokines and evolution: in vitro effects of IL-1 alpha, IL-1 beta, TNF-alpha and TNF-beta on an ancestral type of stress response. (1995) (11)
Immunosenescence and Altered Vaccine Efficiency in Older Subjects: A Myth Difficult to Change (2022) (11)
Specific features of the oldest old from the Longevity Blue Zones in Ikaria and Sardinia (2021) (11)
Polymorphisms of the IL-6 gene increase the risk for late onset Alzheimer's disease and affected IL-6 plasma levels (2000) (11)
A Meta-Analysis of Brain DNA Methylation Across Sex, Age, and Alzheimer's Disease Points for Accelerated Epigenetic Aging in Neurodegeneration (2021) (11)
Aging and Caloric Restriction Modulate the DNA Methylation Profile of the Ribosomal RNA Locus in Human and Rat Liver (2020) (11)
Zinc-Induced Metallothionein in Centenarian Offspring From a Large European Population: The MARK-AGE Project (2018) (11)
Plasminogen activator inhibitor-1 plasma level increases with age in subjects with the 4G allele at position -675 in the promoter region (2004) (11)
Biology and Genetics of Human Longetivity (1998) (11)
How to classify the oldest old according to their health status: A study on 1160 subjects belonging to 552 90+ Italian sib-ships characterized by familial longevity recruited within the GEHA EU Project (2013) (11)
Selective thymus-derived cell enrichment in the rat spleen as a result of immunodepression by urethan. (1972) (11)
Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation (2007) (11)
Thyroid hormones and frailty in persons experiencing extreme longevity (2020) (11)
Regulation of thromboxane A2 biosynthesis in platelet-free human monocytes and the possible role of polypeptide growth factor(s) in the induction of cyclooxygenase system. (1986) (11)
Erythropoietin (EPO) haplotype associated with all-cause mortality in a cohort of Italian patients with Type-2 Diabetes (2019) (10)
Antiproliferative activity of 3-aminobenzamide in A431 carcinoma cells is associated with a target effect on cytoskeleton. (1996) (10)
Failure to replicate an association of rs5984894 SNP in the PCDH11X gene in a collection of 1,222 Alzheimer's disease affected patients. (2010) (10)
Gut neuroendocrine cells: relationship to the proliferative activity and apoptosis of mucous epitheliocytes in aging. (2001) (10)
3-Aminobenzamide induces cytoskeleton rearrangement in M14 melanoma cells. (1994) (10)
Vitamin B-6 intake is related to physical performance in European older adults: results of the New Dietary Strategies Addressing the Specific Needs of the Elderly Population for Healthy Aging in Europe (NU-AGE) study (2021) (10)
Molecular variation of human HSP90alpha and HSP90beta genes in Caucasians. (2003) (10)
Immunoproteasome in Macaca fascicularis: no age-dependent modification of abundance and activity in the brain and insight into an in silico structural model. (2008) (10)
The Effect on Rat Thymocytes of the Simultaneous In Vivo Exposure to 50-Hz Electric and Magnetic Field and to Continuous Light (2004) (10)
Epigenetic DNA methylation changes in episodic and chronic migraine (2018) (10)
A novel mitochondrial DNA-like sequence insertion polymorphism in Intron I of the FOXO1A gene. (2004) (9)
Simple sugars inhibit proliferation of human T lymphocytes in autologous and allogeneic mixed lymphocyte reactions. (1987) (9)
Phagocytosis of Mycoplasma pneumoniae and Acholeplasma laidlawii measured as inhibition of [3H]uridine uptake by macrophages. (1986) (9)
Prevalence and loads of torquetenovirus (TTV) in the European MARK-AGE Study population. (2019) (9)
Effect of 4G/5G PAI-1 polymorphism on the response of PAI-1 activity to vitamin E supplementation in Type 2 diabetic patients. (2004) (9)
Sex-Specific Associations of Blood-Based Nutrient Profiling With Body Composition in the Elderly (2019) (9)
Expression pattern of perilipins in human brain during aging and in Alzheimer's disease (2021) (9)
Prothrombin Gene Mutation (G20210A) in Healthy Centenarians (1999) (9)
Beneficial Role of Replacing Dietary Saturated Fatty Acids with Polyunsaturated Fatty Acids in the Prevention of Sarcopenia: Findings from the NU-AGE Cohort (2020) (9)
Continuous remodeling as a key to aging and survival: an interview with Claudio Franceschi. Interview by Suresh I S Rattan. (2003) (9)
Prostaglandin and thromboxane biosynthesis in resting and activated platelet-free monocytes from aged subjects. (1986) (9)
Survival features of EBV-stabilized cells from centenarians: morpho-functional and transcriptomic analyses (2011) (9)
Combination of biomarkers to predict mortality in elderly patients with myocardial infarction (2008) (9)
Adherence of human monocytes to haemodialysis membranes: LFA 1 (CD11a/CD18) CR1 (CD35) and CR3 (CD11b/CD18) triggering promotes the biosynthesis of platelet-activating factor and adherence. (1995) (9)
6 – Electric and Magnetic Field Effects on the Immune System (1994) (9)
Distinct profile of CD34+ cells and plasma-derived extracellular vesicles from triple-negative patients with Myelofibrosis reveals potential markers of aggressive disease (2021) (9)
Molecular remodeling of potassium channels in fibroblasts from centenarians: A marker of longevity? (2010) (9)
Paraoxonase-1 55 LL Genotype Is Associated with No ST-Elevation Myocardial Infarction and with High Levels of Myoglobin (2012) (9)
The carotid plaque as paradigmatic case of site-specific acceleration of aging process: The microRNAs and the inflammaging contribution (2020) (9)
The “Oldest Man on the Planet” (2002) (9)
Evaluation of Lymphocyte Response to the Induced Oxidative Stress in a Cohort of Ageing Subjects, including Semisupercentenarians and Their Offspring (2018) (9)
Poly ( ADP-ribosyl ) ation is involved in the epigenetic control of TET 1 gene transcription (2019) (9)
Propagation of a transmissible cytotoxic activity on cultures of human peripheral blood lymphocytes. (2008) (8)
DNA repair, sensitivity to gamma radiation and to heat shock in lymphocytes from acute, untreated multiple sclerosis patients (1989) (8)
Convergent adaptation of cellular machineries in the evolution of large body masses and long life spans (2017) (8)
Age, sex and BMI influence on copper, zinc and their major serum carrier proteins in a large European population including Nonagenarian Offspring from MARK-AGE study. (2021) (8)
Immune Dysfunction in Primary Biliary Cirrhosis (1989) (8)
Both objective and paradoxical insomnia elicit a stress response involving mitokine production (2020) (8)
Age-Related Epigenetic Derangement upon Reprogramming and Differentiation of Cells from the Elderly (2018) (8)
Modeling the in Vitro 20 S Proteasome Activity : The Effect of PA 28 – αβ and of the Sequence and Length of Polypeptides on the Degradation Kinetics (2008) (8)
A patient with PMP22-related hereditary neuropathy and DBH-gene-related dysautonomia (2015) (8)
Different types of cell death in organismal aging and longevity: state of the art and possible systems biology approach. (2008) (8)
WHEN DID COMMUNICATION IN THE IMMUNE-SYSTEM BEGIN (1994) (8)
Capturing Degeneracy in the Immune System (2007) (8)
Spectrin changes occur in erythrocytes from patients with Fanconi's anemia and their parents. (2000) (8)
Aging and cellular defense mechanisms (1992) (8)
Helper activity of histocompatibility antigens on cell‐mediated immunity (1972) (8)
Inferring the genetic history of lactase persistence along the Italian peninsula from a large genomic interval surrounding the LCT gene. (2015) (8)
The genetics of successful aging. (1998) (8)
Cell death protection by 3-aminobenzamide: impairment of cytoskeleton function in human NK cell-mediated killing. (1994) (8)
Down Syndrome, Ageing and Epigenetics. (2019) (8)
Effect of vanadate of PHA-induced proliferation of human lymphocytes from young and old subjects. (1987) (8)
A microELISA assay to detect anti-liver-specific protein antibodies in the sera of patients with liver diseases. (1983) (8)
Natural cytotoxicity in a freshwater pulmonate mollusc: an unorthodox comparative approach (1991) (8)
Stable State Analysis of an Immune Network Model (1998) (7)
Networks from Gene Expression Time Series: Characterization of Correlation Patterns (2006) (7)
Enhancing Effect of Electromagnetic Exposure on Calciumionophore (A23187), but Not IL-1, Induced Txa2 Release by Human Neutrophils (1991) (7)
History of Research into Ageing/Senescence (2012) (7)
CORTICOTROPIN-RELEASING FACTOR AND ACTH-RELATED FRAGMENTS MODULATE THE PHAGOCYTIC-ACTIVITY OF HUMAN MONOCYTES (1995) (7)
Occurrence and expansion of trisomy 7 in a fibroblast strain from a centenarian individual☆ (1999) (7)
16th IHIW: Immunogenetics of Aging (2013) (7)
ERYTHROCYTE PLASMA MEMBRANES OBTAINED FROM CENTENARIANS SHOW DIFFERENT FUNCTIONAL PROPERTIES (2000) (7)
Mediterranean diet and inflammaging in the elderly: the European project NU-AGE. Preface. (2014) (7)
The Second International Conference “Genetics of Aging and Longevity” (2012) (7)
Low tobacco-related cancer incidence in offspring of long-lived siblings: a comparison with Danish national cancer registry data. (2015) (7)
Mitochondrial DNA and Cancer Epidemiology (2007) (7)
Selective effect on T and B cell subpopulations in rat lymphoid organs after urethan treatment. (1976) (7)
Effect of ADP‐Ribosyl Transferase Inhibitors on the Survival of Human Lymphocytes after Exposure to Different DNA‐Damaging Agents a (1988) (7)
A mathematical model for the immunosenescence. (2001) (7)
Circulating miR‐19a‐3p and miR‐19b‐3p characterize the human aging process and their isomiRs associate with healthy status at extreme ages (2021) (7)
Plasticity of lifelong calorie‐restricted C57BL/6J mice in adapting to a medium‐fat diet intervention at old age (2017) (7)
Applying hydrodynamic pressure to efficiently generate induced pluripotent stem cells via reprogramming of centenarian skin fibroblasts (2019) (7)
Alpine Skiing With total knee ArthroPlasty (ASWAP): impact on molecular and architectural features of musculo‐skeletal ageing (2015) (6)
Free radicals: Only part of the story? (1993) (6)
Systemic inflammatory markers in relation to cognitive function and measures of brain atrophy: a Mendelian randomization study (2022) (6)
Differential course of HIV-1 infection and apolipoprotein E polymorphism (2007) (6)
Attempt to Separate Antibody-Forming Clones of Different Affinity for One Antigenic Determinant on a Macromolecule (1971) (6)
Genetic and environmental influences on serum levels of immunoglobulins and complement components in monozygotic and dizygotic twins. (1988) (6)
Ancient pathogen-driven adaptation triggers increased susceptibility to non-celiac wheat sensitivity in present-day European populations (2016) (6)
Lower platelet count in healthy centenarians correlates with dispersion of the QT interval (2004) (6)
Detrimental links between physical inactivity, metabolic risk and N-glycomic biomarkers of aging (2019) (6)
Metabolite and lipoprotein profiles reveal sex-related oxidative stress imbalance in de novo drug-naive Parkinson’s disease patients (2022) (6)
Accelerated epigenetic aging and inflammatory/immunological profile (ipAGE) in patients with chronic kidney disease (2021) (6)
The hormetic and hermetic role of IL-6 (2022) (6)
Analysis of HLA-DQA, HLA-DQB frequencies in a group of Sardinian centenarians. (2006) (6)
Differential course of HIV-1 infection and APOE polymorphism (2008) (6)
Human longevity: The gender difference (1993) (6)
Erratum: A meta-analysis on age-associated changes in blood DNA methylation: results from an original analysis pipeline for Infinium 450k data (2016) (6)
Reprint of: Musculoskeletal system in the old age and the demand for healthy ageing biomarkers (2014) (6)
Genomic instability: A challenge for aging research (1990) (5)
Circulating perilipin 2 levels are associated with fat mass, inflammatory and metabolic markers and are higher in women than men (2021) (5)
Effects of Pulsed Electromagnetic Fields on the Proliferation of Lymphocytes from Aids Patients, HIV-Seropositive Subjects, and Seronegative Drug Users (1989) (5)
Prostaglandins and cyclic nucleotides as effectors in non-lymphocyte mediated surveillance processes ( short review). (1985) (5)
Immunosenescence: Paradoxes and New Perspectives Emerging from the Study of Healthy Centenarians (1996) (5)
Gut microbiota changes in the extreme decades of human life: a focus on centenarians (2017) (5)
Undulating changes in human plasma proteome across lifespan are linked to disease (2019) (5)
Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains (2012) (5)
Demographic characteristics of Sardinian centenarian genealogies: Preliminary results of the AKeA2 study (2015) (5)
Maternal longevity is associated with lower infant mortality (2014) (5)
New Targets for the Identification of an Anti-Inflammatory Anti-Senescence Activity (2012) (5)
Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjects (2013) (5)
Long-term effects of vaccination on attentional performance. (2004) (5)
Nutritional Factors Modulating Alu Methylation in an Italian Sample from The Mark-Age Study Including Offspring of Healthy Nonagenarians (2019) (5)
Autoantibodies to Poly(ADP-Ribose) Polymerase in Centenarians: A Reappraisal of Grabar’s Hypothesis (2009) (4)
Complex sex-specific age-related changes in DNA methylation including variability, epimutations and entropy (2020) (4)
Encoding the states of interacting proteins to facilitate biological pathways reconstruction (2010) (4)
The Elderly-Nutrient Rich Food Score Is Associated With Biochemical Markers of Nutritional Status in European Older Adults (2019) (4)
Medication Intake Is Associated with Lower Plasma Carotenoids and Higher Fat-Soluble Vitamins in the Cross-Sectional MARK-AGE Study in Older Individuals (2020) (4)
Circulating cell-free DNA in health and disease — the relationship to health behaviours, ageing phenotypes and metabolomics (2022) (4)
Gender and longevity (2015) (4)
Massive parallel sequencing of human whole mitochondrial genomes with Ion Torrent technology: an optimized workflow for Anthropological and Population Genetics studies (2017) (4)
Sudden spontaneous exercise increases myonuclear ubiquination and apoptosis of dystrophin deficent muscle (1996) (4)
Epidemiological and genetic overlap among biological aging clocks: New challenges in biogerontology (2021) (4)
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Biological age of transplanted livers (2018) (4)
The smell of longevity: a combination of Volatile Organic Compounds (VOCs) can discriminate centenarians and their offspring from age-matched subjects and young controls (2019) (4)
Caloric restriction modulates aging rate and sensitivity to oxygen free radical damage in rats (1991) (4)
Antibody response in partridge (Perdix perdix L.) 1. Effect of sex and age on the immune response to sheep red blood cells (SRBC), Newcastle disease virus (NDV) and Brucella abortus (Buck 19). (1985) (4)
Effects of extremely low frequency (ELF) pulsed electromagnetic fields (PEMFs) on immunocompetent cells (1989) (3)
Structural characterization of p53 isoforms due to the polymorphism at codon 72 by mass spectrometry and circular dichroism. (2010) (3)
Immunity, Inflammation and infections during aging (2006) (3)
TCR Vβ repertoire in an Italian longeval population including centenarians. (2001) (3)
olymorphisms of Drug-Metabolizing Enzymes n Healthy Nonagenarians and Centenarians : ifference at GSTT 1 Locus (2001) (3)
Age-related changes on platelet membrane: a study on elderly and centenarian monozygotic twins. (2005) (3)
Gut microbiota ecology: Biodiversity estimated from hybrid neutral-niche model increases with health status and aging (2020) (3)
Statistical strategies and stochastic predictive models for the MARK-AGE data (2015) (3)
Alu insertion site profiling in the human genome (2010) (3)
Prostanoids as second messengers of polypeptide growth factors (2005) (3)
Immune dysfunction in primary biliary cirrhosis (PBC): I. Increased sensitivity of PHA stimulated lymphocyte cultures to indomethacin. (1987) (3)
Age-related changes of thyroid function in both sexes. (1999) (3)
Effects of extremely low frequency (ELF) pulsed electromagnetic fields (PEMFs) on immunocomponent cells. In vitro studies (1989) (3)
Testosterone, gonadotropins, prolactin and sex hormone-binding globulin in healthy centenarians. (1999) (3)
Association of rs3027178 polymorphism in the circadian clock gene PER1 with susceptibility to Alzheimer’s disease and longevity in an Italian population (2021) (3)
Evaluation of adrenal function in aging. (1999) (3)
Role of mitochondrial DNA in longevity, aging and age-related diseases in humans: a reappraisal. (2007) (3)
Purification and partial characterization of serum monocytotropic factor, a platelet-derived cyclooxygenase-inducing polypeptide. (1988) (3)
Invertebrate/Vertebrate Neuroendocrine and Immune Systems: Commonality of Mechanisms and Signal Molecules (1996) (3)
Identification of a T cell gene expression clock obtained by exploiting a MZ twin design (2017) (3)
Nucleoside transport in activated macrophages. (1989) (3)
Metabonomics and Gut Microbial Paradigm in Healthy Aging (2015) (3)
Regulatory T cells from patients with end-stage organ disease can be isolated, expanded and cryopreserved according good manufacturing practice improving their function (2019) (3)
An emerging role of astrocytes in aging/neuroinflammation and gut-brain axis with consequences on sleep and sleep disorders (2022) (3)
Synergistic Immunodepressive Effect of 7,12-Dimethylbenz[a] Anthracene and Urethan in the Rat 1 (1971) (3)
No association between frailty index and epigenetic clocks in Italian semi-supercentenarians (2021) (3)
Genotype of inflammatory cytokines in limbal stem cell graft in Italian patients. (2005) (3)
DLX5/6 GABAergic Expression Affects Social Vocalization: Implications for Human Evolution (2020) (3)
Frequency and prognostic value of HLA antigens in osteosarcoma patients. (2008) (3)
Cytotoxicity and cell death: studies on molluscan cells and evolutionary considerations. (1992) (3)
Features of age-related response to sleep deprivation: in vivo experimental studies (2021) (3)
Thymus as a Possible Target of 50 Hz Electric and Magnetic Fields (1999) (3)
Neuroimmune System: Aging (2009) (3)
The effects of low frequency pulsing electromagnetic fields on the response of human lymphocytes to lectins (1988) (3)
A Novel Approach to Improve the Estimation of a Diet Adherence Considering Seasonality and Short Term Variability – The NU-AGE Mediterranean Diet Experience (2019) (3)
Ecological Sensing Through Taste and Chemosensation Mediates Inflammation: A Biological Anthropological Approach. (2020) (3)
Twelve-Week Daily Consumption of ad hoc Fortified Milk with ω-3, D, and Group B Vitamins Has a Positive Impact on Inflammaging Parameters: A Randomized Cross-Over Trial (2020) (3)
Insights Into Sibling Relationships and Longevity From Genetics of Healthy Ageing Nonagenarians: The Importance of Optimisation, Resilience and Social Networks (2022) (2)
DNA repair after UV and gamma irradiation. II. Human lymphocytes. (1976) (2)
Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes (2021) (2)
Reticuloendothelial system activity and antibody formation in hibernating hedgehogs (Erinaceus europaeus). (1972) (2)
Lack of correlation between immunodepression and reticuloendothelial system activity in urethan- or 7, 12-dimethylbenz-(a)-anthracene-treated rats. (1972) (2)
Shotgun Metagenomics of Human Gut Microbiota Up to Extreme Longevity and the Increasing Role of Xenobiotics Degradation (2019) (2)
Quality of Life: Psychological Symptoms—Effects of a 2-Month Healthy Diet and Nutraceutical Intervention; A Randomized, Open-Label Intervention Trial (RISTOMED) (2020) (2)
The role of platelet-activating factor in the biocompatibility of hemodialysis membranes. (1996) (2)
Role of connectivity in immune and neural network models: memory development and aging. (2003) (2)
Proteasome Modulation in Brain: A New Target for Anti-Aging Drugs? (2007) (2)
(Bi)sulfite Metabolism in Human Granulocytes: Age‐Dependent Formation of Free Radical Intermediates a (1992) (2)
Role of Epigenetic Therapy in the Modulation of Tumor Growth and Migration in Human Castration-Resistant Prostate Cancer Cells with Neuroendocrine Differentiation (2021) (2)
Bacterial DNAemia in Older Participants and Nonagenarian Offspring and Association With Redox Biomarkers: Results From MARK-AGE Study (2022) (2)
Diverse effects of three furocoumarins on human lymphocyte proliferation. (1989) (2)
Validation and characteristics of Sardinian supercentenarians (2003) (2)
Modulation of apoptosis in human lymphocytes by adenosine analogues. (1998) (2)
The Immune System as a Cognitive System: New Perspectives for Information Technology Society (2003) (2)
Aging, Inflammaging and Adaptation: Comment on "Dynamic and thermodynamic models of adaptation" by A.N. Gorban et al. (2021) (2)
Leading Edge Commentary Geroscience : Linking Aging to Chronic Disease (2014) (2)
Modeling of Immunosenescence and Risk of Death from Respiratory Infections: Evaluation of the Role of Antigenic Load and Population Heterogeneity (2017) (2)
Genetic mechanisms of aging in plants: What can we learn from them? (2022) (2)
Population immunology: Germs, aging and inflammation (2014) (2)
Interdisciplinary views on Molecular Anthropology in the Genomic Era. (2010) (2)
Apo E genotyping in Alzheimer disease (AD): multidimensional counseling by the geriatric assessment unit (GAU) to properly address scientific and bioethical issues emerging from molecular gerontology to geriatric practice. (1998) (2)
Application of Wavelet Packet Transform to detect genetic polymorphisms by the analysis of inter-Alu PCR patterns (2010) (2)
Sex differences in genetic associations with longevity in Han Chinese: sex-stratified genome-wide association study and polygenic risk score analysis (2017) (2)
Genomics and epigenomics (2015) (2)
Development of a pilot project on data sharing among partners of the Italian Hub of Population Biobanks (HIBP): association between lipid profile and socio-demographic variables. (2014) (2)
Intravenous ferric carboxymaltose versus standard medical care in the treatment of iron de fi ciency anemia in patients with chronic kidney disease : a randomized , active-controlled , multi-center study (2013) (2)
Do low molecular weight antioxidants contribute to the Protection against oxidative damage? The interrelation between oxidative stress and low molecular weight antioxidants based on data from the ARK-AGE study. (2021) (2)
Haemagglutinating activity of modeccin (1979) (2)
Extreme longevity: the role of antioxidant enzymes, vitamins, and micronutrients. (2001) (1)
Genetics and anthropology in studies on aging and chagas disease (2010) (1)
lnterleukin-6 is a determinant of PAI-1 levels in diabetic subjects with the 4G allele at position -675 of the PAI-1 gene (2006) (1)
Longevity genes across species: conservation versus evolvability (2007) (1)
DNA repair after UV and gamma irradiation. I. Rat spleen cells. (1976) (1)
New tools for the analysis of mitochondrial DNA complete sequences (2013) (1)
Apoptosis and immunosenescence (1995) (1)
Sensitivity to Genotoxic Agents and Immunological Status in a Case of Werner's Syndrome a (1992) (1)
A STOCHASTIC MODEL FOR THE CLONAL EXPANSION AND HOMEOSTASIS OF CYTOTOXIC T LYMPHOCYTES (2003) (1)
CHIVA effectiveness score: the correct one is below. (2012) (1)
Corrigendum to “What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?” [Mechanisms of Ageing and Development 126 (2005) 421–429] (2005) (1)
Immunological Effects of ELF Electric and Magnetic Fields: An Overview (1999) (1)
Reply from Franceschi et al. (1995) (1)
Monosaccharides and Tamm-Horsefal1 Glycopeptide Inhibit Allogeneic Antigen-Induced Lymphocyte Blàstogenesis in One-Way Mixed Lymphocyte Reaction (1982) (1)
[Response of rat thymocytes of mitogens: standardization of a culture micromethod]. (1974) (1)
Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study (2021) (1)
International conference on biomedical aspects of aging research (1998) (1)
Investigating Mitonuclear Genetic Interactions Through Machine Learning: A Case Study on Cold Adaptation Genes in Human Populations From Different European Climate Regions (2020) (1)
[Is it useful to correct the immunological deficit in cancer patients? And with what modality?]. (1985) (1)
Correction: X-chromosome-linked miR548am-5p is a key regulator of sex disparity in the susceptibility to mitochondria-mediated apoptosis (2019) (1)
Genetic Theories of Aging (2019) (1)
[Clinico-immunological study of 6 cases of Behçet's disease]. (1979) (1)
Nutritional Metabonomics: Development And Validation Of Ageing Biomarkers (2013) (1)
Session 16: Ageing and the immune system in vivo (2004) (1)
Autoimmunoregulation and the Importance of Opioid Peptides (1994) (1)
[Binding of 3-methyl-P-dimethylaminoazobenzene to DNA in different organs and in regenerating rat liver]. (1969) (1)
[Down's syndrome. Precocious aging of the immune system]. (1980) (1)
Erratum to: Differential expression of perilipin 2 and 5 in human skeletal muscle during aging and their association with atrophy-related genes (2015) (1)
Corrigendum to “Age-related changes on platelet membrance: A study on elderly and centenarian monozygotic twins” [Experimental gerontology 40/16 (2005) 519–525] (2005) (1)
Estrogen Containing Hormone Replacement Therapy Affects MicroRNAs And Fas/FasL In Genetically Identical Female Twin Pairs: 85 Board #6 May 28, 9 (2014) (1)
Author Correction: Sarcolab pilot study into skeletal muscle’s adaptation to longterm spaceflight (2018) (1)
Accelerated biological aging in people with Down syndrome with full and segmental trisomy 21 begins in childhood as revealed by immunoglobulin G glycosylation (2021) (1)
Contribution of invertebrate models to aging and longevity studies (2012) (1)
Abstract 1229: Clonal hematopoiesis of indeterminate potential (CHIP), centenarians and age-related cardiovascular risk: Is TET2 the culprit (2018) (1)
Response by Giuliani et al to Letter Regarding Article, "Genetics of Human Longevity Within an Eco-Evolutionary Nature-Nurture Framework". (2019) (1)
The Quest for Longevity and the End of Utopia (2011) (1)
On the Way to Longevity: How to Combat Neuro-Degenerative Disease (2013) (1)
Inflammaging and Its Role in Ageing and Age-Related Diseases (2016) (1)
The New Antigenic Ecospace of the Globalized World and its Impact on the Immune System: The Battleground of Trade-off and Antagonistic Pleiotropy (2014) (1)
Aging and Longevity in Animal Models and Humans (2009) (1)
Network markers of DNA methylation in neurodegenerative diseases (2020) (1)
MATURATION OF THE IMMUNE RESPONSE IN VITRO (1972) (1)
Mitochondrial DNA and aging: Study on heteroplasmy levels with DHPLC technology within the EU project MARKAGE (2013) (1)
Pathological Relevance of the Natural Immune System (2005) (1)
Replication studies in longevity: puzzling findings in Danish centenarians at the 3′APOB–VNTR locus (2001) (1)
Protein intake and bone mineral density: Cross‐sectional relationship and longitudinal effects in older adults (2022) (1)
THE METABOLIC SYNDROME: IL-10 POLYMORPHISMS INFLUENCE ON SEROLOGICAL AND HAEMATOLOGICAL PARAMETERS IN TYPE 2 DIABETES. (2007) (1)
World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2020): ESCEO-WHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Aging Symposium Abstracts (ESCEO-WHOCC) (2020) (1)
Health Status and Quality of Life at Extremely Advanced Ages: an Investigation on People 98 Years of Age and Over in a Province of Northern Italy. (2008) (1)
Heterogeneity of prodromal Parkinson symptoms in siblings of Parkinson disease patients (2021) (1)
The nucleolar size is associated to the methylation status of ribosomal DNA in breast carcinomas (2014) (1)
Blood circulating miR-28-5p and let-7d-5p associate with premature ageing in Down syndrome (2022) (1)
Fertility decline and the emergence of excess female survival in post-reproductive ages in Italy (2022) (1)
A Targeted Epigenetic Clock for the Prediction of Biological Age (2022) (1)
DNA Methylation Analysis of Ribosomal DNA in Adults With Down Syndrome (2022) (1)
Opposite role of CCR5 polymorphisms in cardiovascular diseases and longevity. (2005) (0)
Liver Aging in Transplantation: Future Perspective on Donor-Recipient Age-Mismatch (2011) (0)
Genetics, gender and longevity (2006) (0)
IMMUNOLOGICAL EVALUATION IN 5 CHILDREN AFFECTED BY HBsAG POSITIVE CHRONIC PERSISTENT HEPATITIS BEFORE AND AFTER A TREATMENT WITH LEVAMISOLE (1979) (0)
Circulating muscle-derived MIR-206 links skeletal muscle dysfunction to cardiac autonomic denervation (2020) (0)
Muscle-specific Plin2 down-regulation affects accumulation of ectopic lipid metabolites including ceramides (2016) (0)
influence is operating throughout the lifespan of the individual and that its deterioration may represent an important component of the aging processes 29. Conclusions and perspectives (1981) (0)
Apoptosis, aging and reactive oxygen species: studies in Fanconi's Anemia. (1997) (0)
Increased immunogenicity of TSTA on heterokaryocytes of syngeneic tumoral and allogeneic normal cells (1974) (0)
Professor Dr. Mark Mattson’s special contributions to ageing research and neuroscience (2019) (0)
Megakaryocytopoiesis in bone marrow-derived stromal-hemopoietic cells co-cultures: action of Tamm-Horsfall glycoprotein. (1984) (0)
A randomized trial on the effect of a full dietary intervention on ageing in European elderly people: the Nu-Age study (2013) (0)
Chronic exposure to 50 Hz-SInusolidal electric and magnetic fields:phenotypical study of immune system cells in an in vivo model. (1997) (0)
A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants (2022) (0)
[Chronic persistent HBsAg positive hepatitis in children. II. Effect of treatment with levamisole]. (1978) (0)
DNA and cell death (1991) (0)
Call for articles on neglected topics (2019) (0)
Apolipoprotein E levels in patients with probable Alzheimer S disease are affected by paraoxonase polymorphisms (2000) (0)
BECHET'S DISEASE: IMMUNOLOGICAL STUDY OF 5 CASES (1979) (0)
Further Studies on the Mitogenic Activity, Sugar Specificity and Affinity Properties of Vicia sativa Lectin (1982) (0)
Multiscale gene-expression dynamics and pathways co-regulation changes by conditional transcription factor activation (2006) (0)
Gene expression pattern modifications in cardiac hypertrophy induced by pressure overload conditioning (2007) (0)
Impact of Nutrition on Adult Vaccination Efficacy (2019) (0)
health relevance of the modification of low-grade inflammation in ageing: Could nutrition play a role? : 149/475. (2015) (0)
Class III allele frequencies and complement activity in italian healthy centenarians (1993) (0)
Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans (2020) (0)
UNDULATIONS OF THE PLASMA PROTEOME DEFINE DISTINCT STAGES OF HUMAN LIFESPAN AND REVEAL ACCELERATED AGING IN ALZHEIMER’S DISEASE (2019) (0)
Erythropoietin (EPO) haplotype associated with all-cause mortality in a cohort of Italian patients with Type-2 Diabetes (2019) (0)
Frailty in Old Age Is Associated with Altered Cytokine Production in Response to TLR Ligation (2019) (0)
ProteaMAlg: a Proteasome Modelling Algorithm to address the complexity of intracellular protein degradation kinetics (2008) (0)
Impact Of Physical Activity On N-glycan Profile In Older Adults (2019) (0)
Heterogeneity of Cellular Senescence: Cell Type-Specific and Senescence Stimulus-Dependent Epigenetic Alterations (2023) (0)
Computational dissection of large gene-expression dynamics (by the correlation method) reveals pathways co-regulation changes by conditional transcription factor activation (2006) (0)
Myotendinous and neuromuscular adaptation to long-term spaceflight: Results from the sarcolab pilot study (2016) (0)
The form of the paper : Regular Paper Biochemistry , Protein Interaction and Recognition The adapter protein CD 2 AP binds to p 53 protein in the cytoplasm and can discriminate its polymorphic variants P 72 R (2014) (0)
[A case of active chronic hepatitis with antimicrosomal and antinuclear antibodies]. (1977) (0)
Slug / b-Catenin e Dependent Proin fl ammatory Phenotype in Hypoxic Breast Cancer Stem Cells (2013) (0)
EXTRACELLULAR MITOCHONDRIAL DNA PLASMA LEVELS INCREASE DURING AGING AND LONGEVITY: IMPLICATIONS FOR "INFLAMMAGING" (2011) (0)
A simplified mathematical model for the immune system with" network" characteristics (1995) (0)
Quantification of Mediator Relevance in Immune Cell Network (2007) (0)
Muscle-speci fi c Perilipin 2 down-regulation affects lipid metabolism and induces myo fi ber hypertrophy (2018) (0)
The Neuroimmunology of Stress from Invertebrates to Man 1 1 Progress in Neurobiology, Volume 48, Numbers 4 5 (1996) (0)
Ancient pathogen-driven adaptation triggers increased susceptibility to non-celiac wheat sensitivity in present-day European populations (2016) (0)
Carboxyfullerens reduce apoptotic death induced in cultured human keratinocytes by ultraviolet radiation (1998) (0)
Letter: Immunosuppression by phenytoin. (1976) (0)
Gene-centric networks for multiscale transcriptome analysis and modelling (2007) (0)
Human Longevity Aging of the Immune System as a Prognostic Factor for (2016) (0)
The role of genetics and epigenetics in sex differences in human survival (2023) (0)
Gene expression profiling in T cells with ageing: 2. analysis of time series results encompassing the whole human lifespan (2006) (0)
Analysis of mitochondrial DNA sequence variations in type 2 diabetes patients characterized for haplogroup affiliation (2010) (0)
SUN-P108: Effects of a 2-Month Dietand Nutraceutical Intervention on Quality of Life and Depression with Respect to Inflammaging: Ristomed, an Open Label Intervention Trial (2016) (0)
Untargeted metabolomics reveals pre-frailty sub-phenotypes in elderly (2017) (0)
Role of TLR Polymorphisms in Aging and Age-Related Diseases (2017) (0)
DNA polymerase activity in proliferating and antigen-stimulated tissues. (1979) (0)
Survival features of EBV-stabilized cells from centenarians: morpho-functional and transcriptomic analyses (2011) (0)
Exercise induces ubiquination and apoptosis in dystrophin-deficient muscle of mice (1997) (0)
Author Correction: Erythropoietin (EPO) haplotype associated with all-cause mortality in a cohort of Italian patients with Type-2 Diabetes (2020) (0)
Do nonagenarian siblings provide mutual support? Insights from the EU GeHA project (2012) (0)
[Responses of mouse spleen cells to PHA and to Con A. Effect of the concentration of cells and mitogen in a culture micromethod]. (1976) (0)
Correlation analysis of gene expression time series at multiple scales: from the entire genome to metabolic and signalling pathways (2006) (0)
OP-MOLB190067 1254..1269 (2019) (0)
Abstract A15: Epigenetic up-regulation of ribosome biogenesis and more aggressive phenotype triggered by the lack of the histone demethylase JHDM1B in mammary epithelial cells (2017) (0)
Contributors to immune senescence during treated HIV-1 infection (2017) (0)
Conserved and species-specific molecular denominators in mammalian skeletal muscle aging (2017) (0)
Review Mitochondrial DNA involvement in human longevity (2006) (0)
3-Aminobenzamide protection from apoptosis: The role of cytoskeleton (1995) (0)
Mitochondrial haplogroups in a Sardinian centenarian population. (2006) (0)
Analysis of mitochndrial membrane potential [delta psi] with fluorescent probes (1997) (0)
LONGEVITY AND MYOCARDIAL INFARCTION: ROLE OF ALPHA1-ANTITRYPSIN DEFICENCY (2004) (0)
Gene expression profiling of Healthy Centenarians (2001) (0)
Mitochondria, Aging, and Disease: A Genomic Perspective (2003) (0)
Author response: Whole-genome sequencing analysis of semi-supercentenarians (2021) (0)
[Chronic persistent HBsAG positive hepatitis in children. I. Subpopulations of T and B lymphocytes]. (1978) (0)
Home administration of Pamidronate in patients with bone metastases from various types of cancers. Using an intermate infusion device. (2000) (0)
Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains (2021) (0)
Progetto Neurooncologia Emilia Romagna - PERNO (2008) (0)
Brain aging and garbage cleaning (2020) (0)
The epigenetic landscape of age-related diseases: the geroscience perspective (2017) (0)
Towards an unifying perspective of the fundamental properties and structural principles governing the immune system (2008) (0)
Association between fat-soluble vitamins and self-reported health status: a cross-sectional analysis of the MARK-AGE cohort (2021) (0)
MicroRNA profiles of human peripheral arteries and abdominal aorta in normal conditions: MicroRNAs-27a-5p, -139-5p and -155-5p emerge and in atheroma too (2021) (0)
Sarcolab pilot study into skeletal muscle’s adaptation to long-term spaceflight (2018) (0)
A novel action for adenosine suggested by apoptosis of astroglial cells in rat brain primary cultures (1995) (0)
Author Correction: Sarcolab pilot study into skeletal muscle’s adaptation to longterm spaceflight (2018) (0)
K252a, a high affinity NGF-receptor (trk) inhibitor, induces apoptosis in cultured human keratinocytes. (1995) (0)
Differential expression of perilipin 2 and 5 in human skeletal muscle during aging and their association with atrophy-related genes (2015) (0)
Association of Torquetenovirus viremia with physical frailty and cognitive impairment in three independent European cohorts. (2022) (0)
Epigenomic signature of the progeroid Cockayne syndrome exposes distinct and common features with physiological ageing (2021) (0)
Compared effects of N-hydroxyurethan, urethan and hydroxyurea on DNA synthesis. In vivo and in vitro studies (1977) (0)
Erratum to: Differential expression of perilipin 2 and 5 in human skeletal muscle during aging and their association with atrophy-related genes (2015) (0)
HUMAN LYMPHOC'flE PROLIFERATIIN VITRO AND DNA REPAIR (1988) (0)
A General Learning Rule for Network Modeling of Neuroimmune Interactome (2005) (0)
Down Syndrome: Neuropsychological phenotype and mitochondrial DNA (2012) (0)
Self‑rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains Konstanzer Online-Publikations-System (KOPS) URL: (2021) (0)
Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer’s disease in comparison with healthy aging (2020) (0)
Small immunological clocks identified by Deep Learning and Gradient Boosting (2023) (0)
The smell of longevity: a combination of Volatile Organic Compounds (VOCs) can discriminate centenarians and their offspring from age-matched subjects and young controls (2019) (0)
Heterogeneity of prodromal Parkinson symptoms in siblings of Parkinson disease patients (2021) (0)
Disease classification for whole-blood DNA methylation: Meta-analysis, missing values imputation, and XAI (2022) (0)
Role of Non-feminizing Estrogens in Brain Protection from Cerebral Ischemia and Alzheimer ’ s Disease Neuropathology (2016) (0)
Remodelling of biological parameters during human ageing: evidence for complex regulation in longevity and in type 2 diabetes (2011) (0)
Distinct profile of CD34+ cells and plasma-derived extracellular vesicles from triple-negative patients with Myelofibrosis reveals potential markers of aggressive disease (2021) (0)
Cognitive and Functional Old Subjects with Impaired Health and Very Response to Human Cytomegalovirus in Intense Antiextracellular Adaptive Immune (2010) (0)
DNA repair after gamma radiation and high temperature in peripheral blood lymphocytes from MS patients (1987) (0)
P1-339 mtDNA inherited and somatic variability in Alzheimer’s disease (2006) (0)
NACHR4 594C/T SNP IN ALZHEIMER’S DISEASE (2005) (0)
Gender-differences in centenarians: Health status and life-style (2013) (0)
Naïve and memory CD8 T cell pool homeostasis in advanced aging: impact of age and of antigen-specific responses to cytomegalovirus (2013) (0)
Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity. (2023) (0)
MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling (2012) (0)
Identification of a T cell gene expression clock obtained by exploiting a MZ twin design (2017) (0)
Metabolite and lipoprotein profiles reveal sex-related oxidative stress imbalance in de novo drug-naive Parkinson’s disease patients (2022) (0)
Role of IGF1 system in human longevity. A study in a wide population of centenarians and centenarians' offspring (2010) (0)
Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians (2019) (0)
Epigenetic clocks suggest accelerated aging in patients with isolated REM Sleep Behavior Disorder (2023) (0)
The Malignant Hemopoietic Clone of Triple Negative Patients with Myelofibrosis Shows in Vitro Functional Defects but Is Highly Responsive to the Pro-Survival Signals of Circulating Autologous Microvesicles (2018) (0)
Ageing of the human metaorganism: the microbial counterpart (2011) (0)
Inhibition and potentiation of T lymphocyte response to mitogens. Studies using two mitogenic stimuli simultaneously. (1978) (0)
Regulatory T cells from patients with end-stage organ disease can be isolated, expanded and cryopreserved according good manufacturing practice improving their function (2019) (0)
Forthcoming papers Effect of hyperthermia on the internal microviscosity of erythrocytes and lymph- ocytes : a spin label study (1990) (0)
Deep Learning vs Gradient Boosting in age prediction on immunology profile (2022) (0)
Role of epigenetics in human aging and longevity: genome-wide DNA methylation profile in centenarians and centenarians’ offspring (2012) (0)
Levamisole and HBsAg positive chronic persistent hepatitis. (1978) (0)
Author response: Non-nucleoside reverse transcriptase inhibitor-based combination antiretroviral therapy is associated with lower cell-associated HIV RNA and DNA levels compared to protease inhibitor-based therapy (2021) (0)
DNA methylation in human teeth as a molecular mechanism for age-estimation: a preliminary study focused on the cementum, dentin and pulp of teeth from modern individuals (2016) (0)
Age-dependent alteration in muscle regeneration: the critical role of tissue niche (2013) (0)
Transcriptomic analysis reveals an association of FCGBP with Parkinson’s disease (2022) (0)
Population-specific association of genes for telomere-associated proteins with longevity in an Italian population (2015) (0)
Serum dehydroepiandrosterone sulfate (DHEA-S) and total antioxidant capacity (TAC) in healthy centenarian subjects. (1999) (0)
The expression pattern of GDF15 in human brain changes during aging and in Alzheimer’s disease (2023) (0)
Uncovering the Relationship between Selenium Status, Age, Health, and Dietary Habits: Insights from a Large Population Study including Nonagenarian Offspring from the MARK-AGE Project (2023) (0)
One-year Mediterranean diet promotes epigenetic rejuvenation with country- and sex-specific effects: a pilot study from the NU-AGE project (2020) (0)
Circulating miR-122-5p, miR-92a-3p, and miR-18a-5p as Potential Biomarkers in Human Liver Transplantation Follow-Up (2023) (0)
A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome accelerate short- and long-term inflammaging? (2020) (0)
Long-term human spaceflight and inflammaging: Does it promote aging? (2023) (0)
Genomic stability, anti-inflammatory phenotype and up-regulation of the RNAseH2-dependent RNA:DNA hybrid degrading enzyme in cells from centenarians. (2019) (0)
Evidence for the presence of immunoreactive POMC-derived peptides and cytokines in the thymus of the goldfish (Carassius c. auratus) (2004) (0)
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years (2017) (0)
Electrocardiographic Evaluation of Pregnant Women with Indeterminate Chagas Disease (2010) (0)
Paper alert. (2020) (0)
The invertebrate blueprint of the connection between aging and immune neuroendocrine responses (2009) (0)
DNAging: the forum for molecular biological research on aging (1989) (0)
Adenosine-Induced Apoptosis of C 2 C 12 Myoblastic Cells (2007) (0)
Tu-P10:405 Increased levels of cysteine and homocysteine in Sardinian centenarians (AKEA-project) (2006) (0)
in Very Old Subjects T Cells against Cytomegalovirus + and CD8 + Massive Load of Functional Effector CD4 (2012) (0)
Corrigendum to “Immune parameters identify Italian centenarians with a longer five-year survival independent of their health and functional status” [Exp. Gerontol. 54C (2014) 14–20] (2016) (0)
-174 c>g polymorphism in interleukin-6 gene promoter affects preoperative interleukin-6 serum level in patients with colorectal cancer (2003) (0)
Immunogenetics of longevity: HLA antigens in Italian Centenarians (2001) (0)
Embedding machine-readable proteins interactions data in scientific articles for easy access and retrieval (2008) (0)
Absence of the Prothrombin Gene Variant in Koreans (2012) (0)
Preparation and Purification of Latrodectus Antivenene. (1942) (0)
Perspectives: Is Immunosenescence Clinically Relevant? (2019) (0)
Lifelong calorie restriction and markers of colonic health in aging mice (2018) (0)
The influences on human longe v ity by HUMTHO 1 . STR polymorphism ( Tyrosine Hydroxylase gene ) A relati v e risk approach (2002) (0)
Sysbiohealth Symposium 2007 (2007) (0)
RECIPROCAL FUELLING OF GARBAGING/INFLAMMAGING AND CHRONIC AGE-RELATED DISEASES (2017) (0)
Correction: Analysis of Population Substructure in Two Sympatric Populations of Gran Chaco, Argentina (2014) (0)
L'inevitabile Retorica Del Discorso Scientifico (2005) (0)
Sex differences in genetic associations with longevity in Han Chinese-- Sex-stratified GWAS and polygenic risk score analyses (2017) (0)
K252a, A High-Affinity NGF-Receptor (Trk) Inhibitor, Induces Apoptosis In Human Keratinocytes (1995) (0)
The Properties of Anti-Anthrax Serum: the Protective Antibodies. (0)
Interleukin-10 (IL-10) genotype frequencies in Italian centenarians (2001) (0)

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What Schools Are Affiliated With Claudio Franceschi?

Claudio Franceschi is affiliated with the following schools: