Claudio Tiribelli
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Claudio Tiribelli's Degrees
- PhD Biochemistry University of Milan
- Masters Biotechnology University of Milan
- Bachelors Biology University of Milan
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Why Is Claudio Tiribelli Influential?
(Suggest an Edit or Addition)According to Wikipedia, Claudio Tiribelli is an Italian hepatologist best known for his studies on bilirubin and Kernicterus, a bilirubin-induced neurological condition. Scientific activity Since very early in his career, Tiribelli was fascinated by bilirubin. Expanding upon his research activity and expertise, he founded Bilimetrix together with Richard Wennberg. Bilimetrix developed the first point-of-care device for measuring bilirubin in newborns. Early detection of harmful bilirubin levels would prevent neonatal jaundice and allow the newborns to receive timely and proper treatment.
Claudio Tiribelli's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Fatty Liver Index: a simple and accurate predictor of hepatic steatosis in the general population (2006) (1644)
- Prevalence of and Risk Factors for Hepatic Steatosis in Northern Italy (2000) (1304)
- Prevalence of and risk factors for nonalcoholic fatty liver disease: The Dionysos nutrition and liver study (2005) (1276)
- A new definition for metabolic associated fatty liver disease: an international expert consensus statement. (2020) (1099)
- Drinking habits as cofactors of risk for alcohol induced liver damage (1997) (624)
- Prevalence of chronic liver disease in the general population of northern Italy: The dionysos study (1994) (532)
- The many functions of APE1/Ref-1: not only a DNA repair enzyme. (2009) (455)
- Clinical patterns of hepatocellular carcinoma in nonalcoholic fatty liver disease: A multicenter prospective study (2016) (449)
- Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis. (2008) (416)
- Hepatitis B virus maintains its pro-oncogenic properties in the case of occult HBV infection. (2004) (409)
- Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis (1995) (394)
- Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis (2010) (372)
- Noninvasive in vivo quantitative assessment of fat content in human liver. (1997) (312)
- Global epidemiology of non‐alcoholic fatty liver disease/non‐alcoholic steatohepatitis: What we need in the future (2018) (286)
- Fatty Infiltration of the Liver: Quantification by 1H Localized Magnetic Resonance Spectroscopy and Comparison with Computed Tomography (1993) (273)
- Clinical course and risk factors of hepatitis C virus related liver disease in the general population: report from the Dionysos study (1999) (257)
- The spectrum of liver disease in the general population: lesson from the Dionysos study. (2001) (250)
- International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways (2015) (233)
- Bilirubin-induced neurologic damage--mechanisms and management approaches. (2013) (231)
- Incidence and natural course of fatty liver in the general population: The Dionysos study (2007) (220)
- Severity of liver disease with different hepatitis C viral clones (1991) (204)
- A simple index of lipid overaccumulation is a good marker of liver steatosis (2010) (199)
- Predictors of non-alcoholic fatty liver disease in obese children (2007) (174)
- Prevalence of non-organ-specific autoantibodies and chronic liver disease in the general population: a nested case-control study of the Dionysos cohort (1999) (171)
- Molecular basis of bilirubin-induced neurotoxicity. (2004) (170)
- Suppressor of cytokine signaling 3 (SOCS3) expression and hepatitis C virus–related chronic hepatitis: Insulin resistance and response to antiviral therapy (2007) (163)
- The epidemiology of fatty liver (2004) (159)
- High Prevalence of Celiac Disease in Italian General Population (2001) (155)
- Different genotypes of hepatitis C virus are associated with different severity of chronic liver disease (1994) (154)
- Structure and binding of unconjugated bilirubin: relevance for physiological and pathophysiological function. (1994) (152)
- Bilirubin protects astrocytes from its own toxicity by inducing up-regulation and translocation of multidrug resistance-associated protein 1 (Mrp1). (2004) (151)
- Differential expression of the multidrug resistance‐related proteins ABCb1 and ABCc1 between blood‐brain interfaces (2008) (147)
- New concepts in bilirubin encephalopathy (2003) (146)
- The pediatric NAFLD fibrosis index: a predictor of liver fibrosis in children with non-alcoholic fatty liver disease (2009) (140)
- Unbound (free) bilirubin: improving the paradigm for evaluating neonatal jaundice. (2009) (133)
- Hepatitis C virus and non‐Hodgkin's lymphomas (1996) (130)
- Role of cytokines in ethanol-induced cytotoxicity in vitro in Hep G2 cells. (1998) (125)
- Neonatal Jaundice in Low- and Middle-Income Countries: Lessons and Future Directions from the 2015 Don Ostrow Trieste Yellow Retreat (2016) (121)
- Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease (2012) (120)
- A Novel Perspective on the Biology of Bilirubin in Health and Disease. (2016) (119)
- Familial clustering of Helicobacter pylori infection: population based study. (1999) (118)
- Looking to the horizon: the role of bilirubin in the development and prevention of age-related chronic diseases. (2015) (115)
- Affinity of Human Serum Albumin for Bilirubin Varies with Albumin Concentration and Buffer Composition (2001) (111)
- Bilirubin mediated oxidative stress involves antioxidant response activation via Nrf2 pathway. (2014) (109)
- Reassessment of the Unbound Concentrations of Unconjugated Bilirubin in Relation to Neurotoxicity In Vitro (2003) (108)
- DNA oxidative damage in leukocytes correlates with the severity of HCV-related liver disease: validation in an open population study. (2001) (102)
- Inhibition of glutamate uptake by unconjugated bilirubin in cultured cortical rat astrocytes: role of concentration and pH. (1999) (101)
- Effects of maturation on RNA transcription and protein expression of four MRP genes in human placenta and in BeWo cells. (2003) (98)
- Molecular mechanisms for the hepatic uptake of magnetic resonance imaging contrast agents. (1999) (96)
- Subcellular Localization of APE1/Ref-1 in Human Hepatocellular Carcinoma: Possible Prognostic Significance (2007) (93)
- Epidemiology of fatty liver: an update. (2014) (91)
- Kinetics and Specificity of Feline Leukemia Virus Subgroup C Receptor (FLVCR) Export Function and Its Dependence on Hemopexin* (2010) (90)
- Tauroursodeoxycholic acid protects hepatocytes from ethanol‐fed rats against tumor necrosis factor–induced cell death by replenishing mitochondrial glutathione (2001) (89)
- Bilirubin inhibits the TNFalpha-related induction of three endothelial adhesion molecules. (2009) (86)
- Elevated expression and polymorphisms of SOCS3 influence patient response to antiviral therapy in chronic hepatitis C (2007) (85)
- Natural Course of Chronic HCV and HBV Infection and Role of Alcohol in the General Population: The Dionysos Study (2008) (80)
- A protective effect of breastfeeding on the progression of non-alcoholic fatty liver disease (2009) (80)
- Prevalence of hepatocellular carcinoma and relation to cirrhosis: Comparison of two different cities of the world—Trieste, Italy, and Chiba, Japan (1989) (80)
- Genetic Determinants of Ethanol-Induced Liver Damage (2001) (79)
- The Expression of CD90/Thy-1 in Hepatocellular Carcinoma: An In Vivo and In Vitro Study (2013) (79)
- Isolation of a sulfobromophthalein-binding protein from hepatocyte plasma membrane. (1978) (75)
- Changing molecular epidemiology of hepatitis C virus infection in Northeast Italy (2002) (74)
- The products of YCF1 and YLL015w (BPT1) cooperate for the ATP‐dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae (2000) (74)
- In vitro assessment of the ethanol-induced hepatotoxicity on HepG2 cell line. (1993) (74)
- Effect of tauroursodeoxycholic and ursodeoxycholic acid on ethanol-induced cell injuries in the human Hep G2 cell line. (1995) (72)
- Factors Affecting the Binding of Bilirubin to Serum Albumins: Validation and Application of the Peroxidase Method (2006) (71)
- Biochemical and molecular aspects of the hepatic uptake of organic anions. (1990) (71)
- Bilirubin and the risk of common non-hepatic diseases. (2005) (71)
- Rescue of bilirubin-induced neonatal lethality in a mouse model of Crigler-Najjar syndrome type I by AAV9-mediated gene transfer (2012) (71)
- The expression levels of the translational factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade. (2007) (69)
- Galectin-1 and Its Involvement in Hepatocellular Carcinoma Aggressiveness (2010) (68)
- Life-long correction of hyperbilirubinemia with a neonatal liver-specific AAV-mediated gene transfer in a lethal mouse model of Crigler-Najjar Syndrome. (2014) (67)
- The human multidrug-resistance-associated protein MRP1 mediates ATP-dependent transport of unconjugated bilirubin. (2004) (66)
- Cytotoxicity Is Predicted by Unbound and Not Total Bilirubin Concentration (2007) (66)
- Abc protein transport of MRI contrast agents in canalicular rat liver plasma vesicles and yeast vacuoles. (2001) (63)
- Overoxidation of peroxiredoxins as an immediate and sensitive marker of oxidative stress in HepG2 cells and its application to the redox effects induced by ischemia/reperfusion in human liver (2005) (62)
- Sorafenib Resistance in Hepatocellular Carcinoma: The Relevance of Genetic Heterogeneity (2020) (62)
- Ursodiol in the long-term treatment of chronic hepatitis: a double-blind multicenter clinical trial. (1993) (61)
- Mechanisms for the transport of unconjugated bilirubin in human trophoblastic BeWo cells (2001) (61)
- Reconstitution in vitro of sulfobromophthalein transport by bilitranslocase. (1982) (61)
- Gene Expression of ABC Proteins in Hepatocellular Carcinoma, Perineoplastic Tissue, and Liver Diseases (2002) (60)
- Translational approaches: from fatty liver to non-alcoholic steatohepatitis. (2014) (60)
- Hepatitis C virus infection, HBsAg carrier state and hepatocellular carcinoma: relative risk and population attributable risk from a case-control study in Italy. (1992) (58)
- The molecular basis of bilirubin encephalopathy and toxicity: report of an EASL Single Topic Conference, Trieste, Italy, 1-2 October, 2004. (2005) (58)
- Molecular Determinants in the Transport of a Bile Acid-Derived Diagnostic Agent in Tumoral and Nontumoral Cell Lines of Human Liver (2006) (57)
- Further studies on bilitranslocase, a plasma membrane protein involved in hepatic organic anion uptake. (1982) (57)
- Modulation of Mrp1 (ABCc1) and Pgp (ABCb1) by Bilirubin at the Blood-CSF and Blood-Brain Barriers in the Gunn Rat (2011) (56)
- Proteomic analysis of liver tissues subjected to early ischemia/reperfusion injury during human orthotopic liver transplantation (2006) (56)
- The role of multipotent cancer associated fibroblasts in hepatocarcinogenesis (2015) (55)
- Interferon therapy in chronic hepatitis C virus: Evidence of different outcome with respect to different viral strains (1995) (52)
- Serum type III procollagen peptide in alcoholic liver disease and idiopathic hemochromatosis: Its relationship to hepatic fibrosis, activity of the disease and iron overload (1985) (52)
- Relationship between fatty liver and glucose metabolism: a cross-sectional study in 571 obese children. (2012) (52)
- Role of multidrug resistance-associated protein 1 expression in the in vitro susceptibility of rat nerve cell to unconjugated bilirubin (2007) (50)
- Significance of hepatitis virus infection in the oncogenic initiation of hepatocellular carcinoma. (2016) (50)
- Evidence for carrier-mediated transport of unconjugated bilirubin across plasma membrane vesicles from human placental trophoblast. (2002) (49)
- Ethanol-induced apoptosis in vitro. (1997) (49)
- Gene and functional up-regulation of the BCRP/ABCG2 transporter in hepatocellular carcinoma (2012) (48)
- Bilistick: A Low-Cost Point-of-Care System to Measure Total Plasma Bilirubin (2012) (48)
- Hepatic cancer stem cells and drug resistance: Relevance in targeted therapies for hepatocellular carcinoma. (2010) (47)
- Cellular localization of sulfobromophthalein transport activity in rat liver. (1986) (47)
- The interplay between hepatic stellate cells and hepatocytes in an in vitro model of NASH. (2015) (47)
- The importance of the interaction between hepatocyte and hepatic stellate cells in fibrogenesis induced by fatty accumulation. (2015) (46)
- Vitamin D, Homocysteine, and Folate in Subcortical Vascular Dementia and Alzheimer Dementia (2017) (46)
- Bilirubin-induced cell toxicity involves PTEN activation through an APE1/Ref-1-dependent pathway (2007) (46)
- Bilirubin accumulation and Cyp mRNA expression in selected brain regions of jaundiced Gunn rat pups (2012) (45)
- Blood Flow Changes in Hepatocellular Carcinoma After the Administration of Thalidomide Assessed by Reperfusion Kinetics During Microbubble Infusion: Preliminary Results (2006) (45)
- Treatment options in Western hepatocellular carcinoma: a prospective study of 224 patients. (1998) (45)
- Alterations in the redox state and liver damage: hints from the EASL Basic School of Hepatology. (2013) (45)
- In vitro models for the study of non-alcoholic fatty liver disease. (2011) (45)
- The preS1 domain of hepatitis B virus and IgA cross-react in their binding to the hepatocyte surface. (1992) (44)
- An Animal Model for the Juvenile Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis (2016) (43)
- New concepts in bilirubin and jaundice: Report of the Third International Bilirubin Workshop, April 6‐8, 1995, Trieste, Italy (1996) (43)
- Hepatocyte-derived macrophage migration inhibitory factor mediates alcohol-induced liver injury in mice and patients. (2017) (43)
- Effective treatment of unconjugated hyperbilirubinemia with oral bile salts in Gunn rats. (2009) (42)
- The role of ABC transporters in protecting cells from bilirubin toxicity. (2009) (41)
- Specific Inhibition of the Redox Activity of Ape1/Ref-1 by E3330 Blocks Tnf-Α-Induced Activation of Il-8 Production in Liver Cancer Cell Lines (2013) (41)
- Induction of Mild Hyperbilirubinemia: Hype or Real Therapeutic Opportunity? (2019) (40)
- Multidrug resistance associated protein 1 protects against bilirubin‐induced cytotoxicity (2006) (39)
- HBV, HCV, and TTV detection by in situ polymerase chain reaction could reveal occult infection in hepatocellular carcinoma: comparison with blood markers (2006) (39)
- Epidemiology of hepatitis C virus infection in Italy: the slowly unraveling mystery. (2000) (38)
- Aptamer: A potential oligonucleotide nanomedicine in the diagnosis and treatment of hepatocellular carcinoma (2017) (38)
- Magnetic resonance contrast agents: from the bench to the patient. (2005) (38)
- Bilirubin-induced ER stress contributes to the inflammatory response and apoptosis in neuronal cells (2017) (37)
- Bilitranslocase and sulfobromophthalein/bilirubin-binding protein are both involved in the hepatic uptake of organic anions. (1993) (37)
- Liver and heart: a new link? (2008) (37)
- Th17 involvement in nonalcoholic fatty liver disease progression to non-alcoholic steatohepatitis (2016) (37)
- A proteomic approach to the bilirubin‐induced toxicity in neuronal cells reveals a protective function of DJ‐1 protein (2010) (36)
- The Crosstalk between Tumor Cells and the Microenvironment in Hepatocellular Carcinoma: The Role of Exosomal microRNAs and Their Clinical Implications (2020) (36)
- Bilirubin-Induced Oxidative Stress Leads to DNA Damage in the Cerebellum of Hyperbilirubinemic Neonatal Mice and Activates DNA Double-Strand Break Repair Pathways in Human Cells (2018) (35)
- Bilirubin effect on endothelial adhesion molecules expression is mediated by the NF-kappaB signaling pathway. (2009) (34)
- Bilitranslocase localization and function in basolateral plasma membrane of renal proximal tubule in rat. (1990) (34)
- Functional Induction of the Cystine-Glutamate Exchanger System Xc - Activity in SH-SY5Y Cells by Unconjugated Bilirubin (2011) (34)
- Hepatic uptake of organic anions affects the plasma bilirubin level in subjects with Gilbert's syndrome mutations in UGT1A1 (2001) (34)
- Mechanisms of bilirubin neurotoxicity (2002) (33)
- Transport of sulfobromophthalein and taurocholate in the HepG2 cell line in relation to the expression of membrane carrier proteins. (1992) (33)
- Is it time to change NAFLD and NASH nomenclature? (2017) (33)
- The role of microRNA in the resistance to treatment of hepatocellular carcinoma. (2019) (32)
- Transport and Metabolism at Blood–Brain Interfaces and in Neural Cells: Relevance to Bilirubin-Induced Encephalopathy (2012) (31)
- Attenuation of neuro-inflammation improves survival and neurodegeneration in a mouse model of severe neonatal hyperbilirubinemia (2018) (31)
- Intestinal flora and bilirubin. (2005) (30)
- Gene Expression Analysis in HBV Transgenic Mouse Liver: A Model to Study Early Events Related to Hepatocarcinogenesis (2006) (30)
- Sex differences in the hepatic uptake of sulphobromophthalein in the rat. (1985) (30)
- Hepatitis B virus genotypes, core promoter variants, and precore stop codon variants in patients infected chronically in North‐Eastern Italy (2006) (29)
- Rapid method for detection of extra (TA) in the promoter of the bilirubin-UDP-glucuronosyl transferase 1 gene associated with Gilbert syndrome. (2000) (29)
- A transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells (2009) (29)
- Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis (2015) (29)
- Differential proteomic analysis of hepatocellular carcinoma. (2010) (28)
- New concepts in bilirubin chemistry, transport and metabolism: Report of the second international bilirubin workshop, April 9–11, 1992, trieste, Italy (1990) (28)
- Mechanisms of hepatic uptake of organic anions. (1986) (28)
- Evidence for the existence of a carrier for bromosulphonphthalein in the liver cell plasma membrane (1974) (27)
- SOCS3 and IRS-1 gene expression differs between genotype 1 and genotype 2 hepatitis C virus-infected HepG2 cells (2009) (27)
- Spleen Stiffness Probability Index (SSPI): A simple and accurate method to detect esophageal varices in patients with compensated liver cirrhosis. (2019) (27)
- A comparative characterization of the circulating miRNome in whole blood and serum of HCC patients (2019) (27)
- Clinical, biochemical and histological features of primary haemochromatosis: a report of 67 cases. (2008) (26)
- In vitro and in vivo hepatic transport of the magnetic resonance imaging contrast agent B22956/1: role of MRP proteins. (2002) (26)
- The Biological Effects of Bilirubin Photoisomers (2016) (26)
- New molecular targets for functionalized nanosized drug delivery systems in personalized therapy for hepatocellular carcinoma (2017) (26)
- Upregulation in the expression of multidrug resistance protein Mrp1 mRNA and protein by increased bilirubin production in rat. (2003) (26)
- Repeated AAV-mediated gene transfer by serotype switching enables long-lasting therapeutic levels of hUgt1a1 enzyme in a mouse model of Crigler–Najjar Syndrome Type I (2017) (26)
- An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs (2021) (26)
- The cytotoxic effect of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells is modulated by the expression level of MRP1 but not MDR1. (2009) (25)
- Serum marker of type III procollagen in patients with idiopathic hemochromatosis and its relationship to hepatic fibrosis. (1983) (25)
- Serum miRNA Are Promising Biomarkers for the Detection of Early Hepatocellular Carcinoma after Treatment with Direct-Acting Antivirals (2019) (25)
- Modeling, identification and parameter estimation of bilirubin kinetics in normal, hemolytic and Gilbert's states. (1975) (25)
- Novel Kinetic Insights into Treatment of Unconjugated Hyperbilirubinemia: Phototherapy and Orlistat Treatment in Gunn Rats (2006) (25)
- Natural history of HBV infection: a 9 years follow up of the dionysos cohort (2002) (25)
- Bilitranslocase is the protein responsible for the electrogenic movement of sulfobromophthalein in plasma membrane vesicles from rat liver: immunochemical evidence using mono- and poly-clonal antibodies. (1989) (25)
- Comparison between Bilistick System and transcutaneous bilirubin in assessing total bilirubin serum concentration in jaundiced newborns (2017) (24)
- Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma (2019) (24)
- Isolation of bilitranslocase, the anion transporter from liver plasma membrane for bilirubin and other organic anions. (1989) (24)
- Reversal of ethinylestradiol-induced cholestasis by epomediol in rat. The role of liver plasma-membrane fluidity. (1989) (24)
- Circulating Long and Circular Noncoding RNA as Non-Invasive Diagnostic Tools of Hepatocellular Carcinoma (2021) (24)
- Albumin binding of unconjugated [3H]bilirubin and its uptake by rat liver basolateral plasma membrane vesicles. (1996) (24)
- Epomediol ameliorates pruritus in patients with intrahepatic cholestasis of pregnancy. (1992) (24)
- Neuro-inflammatory effects of photodegradative products of bilirubin (2018) (23)
- Preparation of an antibody recognizing both human and rodent MRP1. (2001) (23)
- Sex differences of nicotinate-induced hyperbilirubinemia in Gilbert's syndrome. Implication of bilitranslocase function. (1985) (23)
- Effects of Oral Administration of Silymarin in a Juvenile Murine Model of Non-alcoholic Steatohepatitis (2017) (23)
- Uptake of [3H]bilirubin in freshly isolated rat hepatocytes: role of free bilirubin concentration (1999) (22)
- Low solubility of unconjugated bilirubin in dimethylsulfoxide – water systems: implications for pKa determinations (2002) (22)
- Homocysteine in Neurology: A Possible Contributing Factor to Small Vessel Disease (2021) (22)
- Modulation of liver-specific cellular response to ethanol in vitro in hep G2 cells. (1998) (22)
- Bilirubin: the yellow hormone? (2021) (22)
- Measurement of the association of cholephylic organic anions with different binding proteins. (1985) (22)
- Unconjugated bilirubin modulates nitric oxide production via iNOS regulation. (2010) (21)
- Hyaluronic acid inhibition by 4-methylumbelliferone reduces the expression of cancer stem cells markers during hepatocarcinogenesis (2019) (21)
- Group 2 innate lymphoid cells exhibit progressively higher levels of activation during worsening of liver fibrosis. (2019) (21)
- In situ polymerase chain reaction detection of transfusion‐transmitted virus in liver biopsy (2002) (21)
- Alterations in the Cell Cycle in the Cerebellum of Hyperbilirubinemic Gunn Rat: A Possible Link with Apoptosis? (2013) (21)
- Effect of bilirubin on cytochrome c oxidase activity of mitochondria from mouse brain and liver (2010) (21)
- Genetic biomarkers for hepatocellular cancer risk in a caucasian population (2017) (21)
- Systematic review and meta-analysis on the adverse events of rimonabant treatment: Considerations for its potential use in hepatology (2009) (21)
- Prevalence of and risk factors for fatty liver in the general population of Northern Italy: the Bagnacavallo Study (2018) (21)
- Different morphologic aspects and clinical features in massive hepatic amyloidosis. (1984) (20)
- A Hypothesis for Using Pathway Genetic Load Analysis for Understanding Complex Outcomes in Bilirubin Encephalopathy (2016) (20)
- Chronic administration of ursodeoxycholic and tauroursodeoxycholic acid changes microsomal membrane lipid content and fatty acid compositions in rats. (1996) (20)
- New concepts in bilirubin neurotoxicity and the need for studies at clinically relevant bilirubin concentrations. (2001) (20)
- Diagnostic Performance Analysis of the Point-of-Care Bilistick System in Identifying Severe Neonatal Hyperbilirubinemia by a Multi-Country Approach (2018) (20)
- Evaluation of region selective bilirubin-induced brain damage as a basis for a pharmacological treatment (2017) (20)
- 1H NMR spectroscopic studies of lipid extracts from human fatty liver. (1993) (19)
- Bilirubin, a curse and a boon (2003) (19)
- Differentiation between stages of non-alcoholic fatty liver diseases using surface-enhanced Raman spectroscopy. (2020) (19)
- Is there an association between commonly employed biomarkers of liver fibrosis and liver stiffness in the general population? (2020) (19)
- The molecular basis of jaundice: An old symptom revisited (2017) (19)
- The activation of autophagy protects neurons and astrocytes against bilirubin-induced cytotoxicity (2017) (19)
- Cross-Talk Between Neurons and Astrocytes in Response to Bilirubin: Adverse Secondary Impacts (2014) (19)
- Serum Stem Cell Growth Factor Beta for the Prediction of Therapy Response in Hepatocellular Carcinoma (2018) (18)
- The Role of microRNAs in the Cisplatin- and Radio-Resistance of Cervical Cancer (2021) (18)
- UGT1A polymorphisms as genetic biomarkers for hepatocellular carcinoma risk in Caucasian population (2017) (18)
- Molecular aspects of organic anion uptake in liver. (1996) (18)
- Dose dependence of nicotinic acid-induced hyperbilirubinemia and its dissociation from hemolysis in Gilbert's syndrome. (1986) (17)
- Abnormal hepatic uptake of low doses of sulfobromophthalein in Gilbert's syndrome: The role of reduced affinity of the plasma membrane carrier of organic anions (1990) (17)
- Digital liver biopsy: Bio-imaging of fatty liver for translational and clinical research (2018) (17)
- Drug-induced acute cholestatic liver damage in a patient with mutation of UGT1A1 (2007) (17)
- Liver cirrhosis and pregnancy. (2006) (17)
- Obeticholic acid and INT-767 modulate collagen deposition in a NASH in vitro model (2020) (17)
- Bilirubin, Intestinal Integrity, the Microbiome, and Inflammation. (2020) (17)
- The multiple origin of cancer stem cells in hepatocellular carcinoma. (2015) (17)
- Comparison of nicotinic acid- and caloric restriction-induced hyperbilirubinaemia in the diagnosis of Gilbert's syndrome. (1985) (16)
- Role of brain cytochrome P450 mono-oxygenases in bilirubin oxidation-specific induction and activity (2016) (16)
- Abnormal apolipoprotein B pre-mRNA splicing in patients with familial hypobetalipoproteinaemia (2006) (16)
- Effect of ethinylestradiol and epomediol on bile flow and biliary lipid composition in rat. (1992) (16)
- Repeated double cross-validation applied to the PCA-LDA classification of SERS spectra: a case study with serum samples from hepatocellular carcinoma patients (2020) (16)
- Kinetics of the inflammatory response induced by free fatty acid accumulation in hepatocytes. (2013) (16)
- Sex steroid modulation of the hepatic uptake of organic anions in rat. (1988) (16)
- X chromosome contribution to the genetic architecture of primary biliary cholangitis. (2021) (16)
- Determinants in the hepatic uptake of organic anions. (1992) (16)
- The implication of bilitranslocase function in the impaired rifamycin SV metabolism in Gilbert's syndrome. (1985) (16)
- Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1-/- lethal mouse model of neonatal hyperbilirubinemia (2016) (16)
- Anti-transglutaminase antibodies and age. (2004) (15)
- Clinical update on non-alcoholic fatty liver disease and steatohepatitis. (2008) (15)
- Relationship between glucose metabolism and non-alcoholic fatty liver disease severity in morbidly obese women (2014) (15)
- ATP-dependent transport of unconjugated bilirubin by rat liver canalicular plasma membrane vesicles. (1998) (15)
- External Validation of Surrogate Indices of Fatty Liver in the General Population: The Bagnacavallo Study (2021) (15)
- Differential proteomic analysis of subfractioned human hepatocellular carcinoma tissues. (2009) (15)
- Accuracy of body mass index in detecting an elevated alanine aminotransferase level in adolescents (2004) (15)
- Sex differences in non-alcoholic fatty liver disease: hints for future management of the disease (2020) (15)
- Body mass index is a good predictor of an elevated alanine transaminase level in the general population: hints from the Dionysos study. (2003) (15)
- Silencing efficacy prediction: a retrospective study on target mRNA features (2015) (15)
- Diagnostic methods for neonatal hyperbilirubinemia: benefits, limitations, requirements, and novel developments (2021) (14)
- Circulatory miRNA as a Biomarker for Therapy Response and Disease-Free Survival in Hepatocellular Carcinoma (2020) (14)
- Optimization of Point-Shear Wave Elastography by Skin-to-Liver Distance to Assess Liver Fibrosis in Patients Undergoing Bariatric Surgery (2020) (14)
- Effect of ursodeoxycholic acid administration on bile duct proliferation and cholestasis in bile duct ligated rat (1993) (14)
- Detection of MRP1 mRNA in human tumors and tumor cell lines by in situ RT-PCR. (2000) (14)
- Cohort effect of HCV infection in liver cirrhosis assessed by a 25 year study. (2000) (13)
- Heterologous Ferredoxin Reductase and Flavodoxin Protect Cos-7 Cells from Oxidative Stress (2010) (13)
- Are non-invasive tests accurate enough to predict hepatic fibrosis in non-alcoholic fatty liver disease (NAFLD)? (2008) (13)
- Earliest Mechanisms of Dopaminergic Neurons Sufferance in a Novel Slow Progressing Ex Vivo Model of Parkinson Disease in Rat Organotypic Cultures of Substantia Nigra (2019) (13)
- Evaluation of liver parenchymal blood flow with contrast-enhanced US: preliminary results in healthy and cirrhotic patients. (2003) (13)
- Occult hepatitis B virus infection. (2000) (13)
- Pitfalls in preparation of (3)H-unconjugated bilirubin by biosynthetic labeling from precursor (3)H-5-aminolevulinic acid in the dog. (2001) (13)
- A rational use of laboratory tests in the diagnosis and management of hepatitis C virus infection. (2003) (13)
- Bilirubin-induced neurological damage (2011) (12)
- The effect of a hydrogen sulfide releasing molecule (Na2S) on the cold storage of livers from cardiac dead donor rats. A study in an ex vivo model. (2015) (12)
- The Extent of Intracellular Accumulation of Bilirubin Determines Its Anti- or Pro-Oxidant Effect (2020) (12)
- Natural Compounds for Counteracting Nonalcoholic Fatty Liver Disease (NAFLD): Advantages and Limitations of the Suggested Candidates (2022) (12)
- Bilirubin-induced neurologic damage. (2014) (12)
- Bilirubin disrupts calcium homeostasis in neonatal hippocampal neurons: a new pathway of neurotoxicity (2020) (11)
- Could Inflammatory Indices and Metabolic Syndrome Predict the Risk of Cancer Development? Analysis from the Bagnacavallo Population Study (2020) (11)
- X‐ray fluorescence elemental mapping and microscopy to follow hepatic disposition of a Gd‐based magnetic resonance imaging contrast agent (2011) (11)
- Bilirubin and inflammation in neurodegenerative and other neurological diseases (2020) (11)
- Weighted miRNA co-expression networks analysis identifies circulating miRNA predicting overall survival in hepatocellular carcinoma patients (2020) (11)
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- Homocysteine in Neurology: From Endothelium to Neurodegeneration (2017) (11)
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- HCV Proteins Modulate the Host Cell miRNA Expression Contributing to Hepatitis C Pathogenesis and Hepatocellular Carcinoma Development (2021) (10)
- The Pros and the Cons for the Use of Silybin-Rich Oral Formulations in Treatment of Liver Damage (NAFLD in Particular). (2015) (10)
- Differences in circulating microRNA signature in Prader–Willi syndrome and non-syndromic obesity (2018) (10)
- Activation of hepatic stem cells compartment during hepatocarcinogenesis in a HBsAg HBV-transgenic mouse model (2018) (10)
- The Fatty liver Index (FLI) 15 years later: a reappraisal (2021) (10)
- Ammonium detoxifying activity is maintained after 72 hours of cold preservation of rat hepatocytes in University of Wisconsin (UW) solution. (2002) (10)
- Estimation of the hepatic blood "flow" by galactose plasma clearance in patients with liver disease. (2008) (10)
- Histone acetylation as a new mechanism for bilirubin-induced encephalopathy in the Gunn rat (2018) (10)
- Modern strategies to identify new molecular targets for the treatment of liver diseases: The promising role of Proteomics and Redox Proteomics investigations (2009) (10)
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- Correction: Specific Inhibition of the Redox Activity of Ape1/Ref-1 by E3330 Blocks Tnf-Α-Induced Activation of Il-8 Production in Liver Cancer Cell Lines (2013) (10)
- Podocyte Expression of Membrane Transporters Involved in Puromycin Aminonucleoside-Mediated Injury (2013) (9)
- Spleen stiffness can be employed to assess the efficacy of spontaneous portosystemic shunts in relieving portal hypertension. (2020) (9)
- The Role of Bilirubin and the Other “Yellow Players” in Neurodegenerative Diseases (2020) (9)
- Incidence of hepatocellular carcinoma in Italy: what could we learn from autoptic studies? (1991) (9)
- COVID-19 Lockdown Effect on Not Institutionalized Patients with Dementia and Caregivers (2021) (9)
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- Screening methods for neonatal hyperbilirubinemia: benefits, limitations, requirements, and novel developments (2021) (7)
- The biological implication of cancer stem cells in hepatocellular carcinoma: a possible target for future therapy (2013) (7)
- HCV, HBV and Alcohol – the Dionysos Study (2011) (7)
- Difference in hepatic uptake of tetra- and di-bromosulfophthalein in rat. Role of hydrophobicity, binding to plasma proteins and affinity for plasma membrane carrier protein. (1993) (7)
- Concomitant primary hemochromatosis and beta-thalassemia trait: iron depletion by erythrocytapheresis and desferrioxamine. (1989) (7)
- Liver Bromosulphonphthalein Transport as a Carrier Mediated Process (1976) (7)
- Carrier-mediated transport of tetrabromosulfonephthalein by rat liver plasma membrane vesicles. (1992) (7)
- Bilirubin accumulation and Cyp mRNA expression in selected brain regions of jaundiced Gunn rat pups (2012) (7)
- Modulation of resting membrane potential of human and rat hepatocytes by sex steroids. (1990) (6)
- A simple in silico strategy identifies candidate biomarkers for the diagnosis of liver fibrosis in morbidly obese subjects (2018) (6)
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- HCC occurrence after DAA treatments: molecular tools to assess the post-treatment risk and surveillance (2020) (6)
- Phenobarbitone Sensitivity of Jaundice in Haemolytic Patients (1973) (6)
- Obesity and not alcohol intake is the main cause of liver steatosis (1998) (6)
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- SPECIFIC-INHIBITION OF THE HEPATIC-UPTAKE OF DIBROMOSULPHTHALEIN (DBSP) BY ANTIBILITRANSLOCASE ANTIBODY (1982) (5)
- The Beneficial Effects of Triterpenic Acid and Acteoside in an In Vitro Model of Nonalcoholic Steatohepatitis (NASH) (2022) (5)
- Competition of bile acids on the sulfobromophthalein uptake in basolateral rat liver plasma membrane vesicles. (1994) (5)
- therapy in chronic hepatitis C SOCS3 influence patient response to antiviral Elevated expression and polymorphisms of (2008) (5)
- Silybin Modulates Collagen Turnover in an In Vitro Model of NASH (2019) (5)
- Celiac Disease and Neurological Manifestations: From Gluten to Neuroinflammation (2022) (5)
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- Phototherapy in neonatal jaundice. (1972) (4)
- Association of Serum Bilirubin Level with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study of 1672 Obese Children (2021) (4)
- Efficient cold transfection of pea ferredoxin‐NADP(H) oxidoreductase into rat hepatocytes (2006) (4)
- Taste perception and expression in stomach of bitter taste receptor tas2r38 in obese and lean subjects (2021) (4)
- Characterization of SCCA-IgM as a biomarker of liver disease in an Asian cohort of patients (2018) (4)
- [Symptomatic effect of epomediol in patients with cholestasis of pregnancy]. (1992) (4)
- Rapid identification system of frontal dysfunction in subclinical hepatic encephalopathy. (2016) (4)
- Vascular network expansion, integrity of blood–brain interfaces, and cerebrospinal fluid cytokine concentration during postnatal development in the normal and jaundiced rat (2022) (4)
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- Translational Approach to the Protective Effect of Bilirubin in Diabetic Kidney Disease (2022) (3)
- Biomarkers for the Detection and Management of Hepatocellular Carcinoma in Patients Treated with Direct-Acting Antivirals (2022) (3)
- The Relevance of SOCS1 Methylation and Epigenetic Therapy in Diverse Cell Populations of Hepatocellular Carcinoma (2021) (3)
- P0340 : Clinical patterns of hepatocellular carcinoma (HCC) in non alcoholic fatty liver disease (NAFLD): A multicenter case-control study (2015) (3)
- Expression and distribution of aquaporin 8 in rat hepatocytes cold stored 72 hours in modified University of Wisconsin and bes-gluconate-sucrose solutions. Study of their correlation with water content. (2012) (3)
- Detection of hepatitis B virus transcripts in patients with chronic liver disease. (1990) (3)
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- Role of brain cytochrome P450 mono-oxygenases in bilirubin oxidation-specific induction and activity (2014) (2)
- Vagaries of impaired transporter function in PFIC 2 and 3 (2005) (2)
- Correction: Aptamer: A potential oligonucleotide nanomedicine in the diagnosis and treatment of hepatocellular carcinoma (2018) (2)
- The mRNA Distribution of Cancer Stem Cell Marker CD90/Thy-1 Is Comparable in Hepatocellular Carcinoma of Eastern and Western Populations (2020) (2)
- Cold storage of liver microorgans in ViaSpan and BG35 solutions: study of ammonia metabolism during normothermic reoxygenation. (2014) (2)
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- Variation in UGT1A1 activity in Gilbert's syndrome. (2001) (2)
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- 698 INCREASED EXPRESSION OF IL-6 AND IL-8 MRNA IN HUMAN IMMORTALIZED HEPATOCYTES AFTER FAT OVERLOAD (2009) (2)
- Clinical patterns of hepatocellular carcinoma (HCC) in non alcoholic fatty liver disease (NAFLD): a multicenter case-control study (2015) (2)
- Adipose Tissue-Liver Axis: Involvement of the TH17 Pathway in the Progression of Human NAFLD (2016) (2)
- Transcutaneous bilirubin measurements: useful, but also reproducible? (2020) (2)
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- The Novel N,N‐bis‐2‐Hydroxyethyl‐2‐Aminoethanesulfonic Acid–Gluconate–Polyethylene Glycol–Hypothermic Machine Perfusion Solution Improves Static Cold Storage and Reduces Ischemia/Reperfusion Injury in Rat Liver Transplant (2019) (2)
- The Assessment of Body Composition in Health and Disease (2006) (2)
- Epomediol ameliorates pruritus of intrahepatic cholestasis of pregnancy (ICP) (1990) (2)
- Antibody Pattern of HCV Infection and Hepatocellular Carcinoma in Italy: A Case Control Study (1994) (2)
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- Disturbances of bilirubin metabolism (2012) (1)
- Survey of health status , nutrition and geography of food selection of chronic liver disease patients (2014) (1)
- Updating the Clinical Application of Blood Biomarkers and Their Algorithms in the Diagnosis and Surveillance of Hepatocellular Carcinoma: A Critical Review (2023) (1)
- Effect of Phototherapy on the Physiologic Cholestasis of the Neonate (1984) (1)
- Recent Hints on the Dual Role of Discs Large MAGUK Scaffold Protein 5 in Cancers and in Hepatocellular Carcinoma. (2022) (1)
- Ape1/Ref-1 mRNA level in human hepatocellular carcinoma is higher in HCV related cancers (2008) (1)
- Liver and heart : A new link ? q (2008) (1)
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- Kernicterus, Bilirubin-Induced Neurological Dysfunction, and New Treatments for Unconjugated Hyperbilirubinemia in Neonates (2012) (1)
- Analysis of p53 and ras gene mutations in hepatocellular carcinoma in Italy (1994) (1)
- Typing core region of hepatitis C virus by polymerase chain reaction: results from North East of Italy (1993) (1)
- Powering the powerhouse: Heme oxygenase‐1 regulates mitochondrial function in non‐alcoholic fatty liver disease (NAFLD) (2023) (1)
- Sex related differences of sulfobromophthalein hepatic transport in rats (1984) (1)
- The urea cycle enzymes activity and its gene expression in rat hepatocytes are not affected by cold storage in University of Wisconsin solution. (2005) (1)
- Immune checkpoint and angiogenic inhibitors for the treatment of hepatocellular carcinoma: it takes two to tangle. (2022) (1)
- MRP1 at apical (maternal-facing) pole of human trophoblasts accounts for the placental transfer of unconjugated bilirubin (UCB) from the fetal to the maternal circulation (2001) (1)
- Circulating miR-3185 as a predictive marker for overall survival in patients with hepatocellular carcinoma (2019) (1)
- Circulating microRNA Associated to Different Stages of Liver Steatosis in Prader–Willi Syndrome and Non-Syndromic Obesity (2020) (1)
- Bilirubin Prevents the TH+ Dopaminergic Neuron Loss in a Parkinson’s Disease Model by Acting on TNF-α (2022) (1)
- Severe neonatal hyperbilirubinemia and the brain: the old but still evolving story (2021) (1)
- On the operational definition of fatty liver (2018) (1)
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- Ficolin-2 Plasma Level Assesses Liver Fibrosis in Non-Alcoholic Fatty Liver Disease (2022) (1)
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- Function and Dysfunction of the Liver: An Overview (2001) (0)
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- γ-Glutamyl transpeptidase and estrogen hormones (1978) (0)
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- Stem cells in the development of hepatocellular carcinoma: identification and expression (2011) (0)
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- Ethanol cytoxicity is reversed by epomediol in Hep G2 cells (1993) (0)
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- Neural precursor cell proliferation and differentiation: Looking at the redox environment and cell defense mechanisms (2010) (0)
- Editorial [Hot Topic: Bilirubin Induced Neurological Damage: From the Cell to the Newborn (Executive Editor: J.D. Ostrow and C. Tiribelli)] (2009) (0)
- 886 SOCS3 AND IRS-1 GENE EXPRESSION DIFFERS BETWEEN GENOTYPE 1 AND GENOTYPE 2 HCV- INFECTED HEPG2 CELLS (2009) (0)
- 250 Sub-cellular expression of Ape1/Ref1 in hepatocellular carcinoma at different stages: Possible prognostic significance (2006) (0)
- Bilirubin 2022: The Past, the Present and the Future (2022) (0)
- Selection and validation of miR-1280 as a suitable endogenous normalizer for qRT-PCR Analysis of serum microRNA expression in Hepatocellular Carcinoma (2020) (0)
- The impact of translational research on gastroenterology. (2014) (0)
- Subject Index Vol. 28, 2010 (2011) (0)
- External validation of biomarkers of fatty liver in the general population: the Bagnacavallo study (2020) (0)
- PO-091 Induction of anti-Fas regulates PUMA and MYC: P53-dependent apoptosis pathway in hepatocellular carcinoma cells (2018) (0)
- Common chemical structure of organic anions sharing carrier mediated hepatic uptake (1990) (0)
- Hepatic expression of ghrelin and adiponectin and their receptors in patients with non-alcoholic fatty liver disease by Misael Uribe et al (2008) (0)
- Renovation of Annals of Hepatology's Scientific Scope: Towards Preventing Rather Than Treating End-Stage Liver Disease. (2018) (0)
- The Multifaceted Aspects of Modern Hepatology. (2021) (0)
- Improvements and problems in preparation of 3H-un-conjugated bilirubin (3H-UCB) by biosynthetic labeling from 3H-δ-aminolevulinic acid (3H-δ-ALA) (2000) (0)
- In silico identification and validation of plasma Ficolin-2 (FCN-2) as non-invasive biomarker of fibrosis in Non-alcoholic Fatty Liver Disease (NAFLD) (2022) (0)
- Editorial: treatments for non‐alcoholic steatohepatitis ‐ still a long way to go (2017) (0)
- A new insight on the stem cell growth factor beta as astrong predictor of therapy response in hepatocellular carcinoma (2018) (0)
- The role of multipotent cancer associated fibroblasts in hepatocarcinogenesis (2015) (0)
- Neuro-inflammatory effects of photodegradative products of bilirubin (2018) (0)
- Molecular Networks in Hepatocellular Carcinoma: Telomerase Extratelomeric Effects (2016) (0)
- Network Analysis for the Discovery of Common Oncogenic Biomarkers in Liver Cancer Experimental Models (2023) (0)
- In vivo quantification of liver steatosis by proton nuclear magnetic resonance (1991) (0)
- T-51 NAFLD to NASH: an experimental study on the early events of fibrosis (2012) (0)
- Mir-106b for HCC patient management after therapy (2015) (0)
- Effect of age and gender in the progression of NAFLD towards NASH in a juvenile mice model (2015) (0)
- Charles E. Ahlfors (1944–2020) (2020) (0)
- Sex difference in intracellular hepatic pH in man (1991) (0)
- 558 Does Bilirubin Affect the Abcc1 (MRP1) Expression in the Brain Parenchyma of the Gunn Rat (2010) (0)
- Ursodeoxycholic acid treatment for unconjugated hyperbillrubinemia: promising results in Gunn rats (2009) (0)
- 579 Bilirubin Upregulates Gene Expression of Slc7A11 and Increases Cystine Uptake Mediated by System X c - in Sh-Sy5Y Neuroblastoma Cells (2010) (0)
- Ex-vivo liver perfusion: a successful technique of liver support (1998) (0)
- 304 DEVELOPMENT OF DOXORUBICIN-RESISTANCE IN HCC: IN-VITRO MOLECULAR INSIGHTS (2012) (0)
- A comparative characterization of the circulating miRNome in whole blood and serum of HCC patients (2019) (0)
- MiR-3201 as a Prognostic Blood Biomarker for Curative Treatments in Hepatocellular Carcinoma (2022) (0)
- Inhibition of Hyaluronic Acid in Hepatocarcinogenesis: A Novel Approach to Target CD44 and Other Cancer Stem Cell Populations (2016) (0)
- [The epidemiology and modes of transmission of Helicobacter pylori infection]. (2000) (0)
- Models of bilirubin neurological damage: lessons learned and new challenges. (2022) (0)
- Lymphocyte subsets, natural killer activity and HLA A, B and DR antigens in idiopathic haemochromatosis (1987) (0)
- Unconjugated bilirubin inhibits glutamate uptake in cortical astrocytes (1998) (0)
- Ungebundenes (freies) Bilirubin: eine bessere Grundlage für die Bewertung des Icterus neonatorum 1 / Unbound (free) bilirubin: improving the paradigm for evaluating neonatal jaundice (2010) (0)
- Jay Donald Ostrow: The yellow giant (2013) (0)
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