Clements Ip
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Biology
Clements Ip's Degrees
- PhD Molecular Biology Stanford University
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(Suggest an Edit or Addition)Clements Ip's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mammary cancer prevention by conjugated dienoic derivative of linoleic acid. (1991) (824)
- Lessons from basic research in selenium and cancer prevention. (1998) (677)
- Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat. (1994) (615)
- Conjugated linoleic acid-enriched butter fat alters mammary gland morphogenesis and reduces cancer risk in rats. (1999) (471)
- In vitro and in vivo studies of methylseleninic acid: evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention. (2000) (408)
- Requirement of essential fatty acid for mammary tumorigenesis in the rat. (1985) (323)
- Chemical form of selenium, critical metabolites, and cancer prevention. (1991) (308)
- Chemical speciation influences comparative activity of selenium-enriched garlic and yeast in mammary cancer prevention. (2000) (295)
- Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology. (2007) (238)
- Activity of methylated forms of selenium in cancer prevention. (1990) (222)
- The efficacy of conjugated linoleic acid in mammary cancer prevention is independent of the level or type of fat in the diet. (1996) (217)
- Mammary cancer prevention by regular garlic and selenium-enriched garlic. (1992) (214)
- cis-9, trans-11 CLA derived endogenously from trans-11 18:1 reduces cancer risk in rats. (2003) (208)
- Selenium‐induced inhibition of angiogenesis in mammary cancer at chemopreventive levels of intake (1999) (206)
- Review of the effects of trans fatty acids, oleic acid, n-3 polyunsaturated fatty acids, and conjugated linoleic acid on mammary carcinogenesis in animals. (1997) (205)
- Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array. (2003) (200)
- Effect of timing and duration of dietary conjugated linoleic acid on mammary cancer prevention. (1995) (199)
- Cancer-protective properties of high-selenium broccoli. (2001) (198)
- Synergistic effect of vitamin E and selenium in the chemoprevention of mammary carcinogenesis in rats. (1983) (189)
- Decrease in linoleic acid metabolites as a potential mechanism in cancer risk reduction by conjugated linoleic acid. (1999) (185)
- New Concepts in Selenium Chemoprevention (2004) (174)
- Conjugated linoleic acid inhibits proliferation and induces apoptosis of normal rat mammary epithelial cells in primary culture. (1999) (169)
- Distribution of conjugated linoleic acid and metabolites in different lipid fractions in the rat liver. (2001) (161)
- Conjugated Linoleic Acid Isomers and Mammary Cancer Prevention (2002) (159)
- Prophylaxis of mammary neoplasia by selenium supplementation in the initiation and promotion phases of chemical carcinogenesis. (1981) (148)
- Morphological and biochemical status of the mammary gland as influenced by conjugated linoleic acid: implication for a reduction in mammary cancer risk. (1997) (147)
- Human Peroxiredoxin 1 and 2 Are Not Duplicate Proteins (2007) (144)
- The anticarcinogenic effect of trans-11 18:1 is dependent on its conversion to cis-9, trans-11 CLA by delta9-desaturase in rats. (2004) (142)
- Prx1 suppresses radiation-induced c-Jun NH2-terminal kinase signaling in lung cancer cells through interaction with the glutathione S-transferase Pi/c-Jun NH2-terminal kinase complex. (2006) (140)
- Comparison of selenium and sulfur analogs in cancer prevention. (1992) (139)
- Prostate Specific Antigen Expression Is Down-Regulated by Selenium through Disruption of Androgen Receptor Signaling (2004) (134)
- Identification of molecular targets associated with selenium-induced growth inhibition in human breast cells using cDNA microarrays. (2002) (134)
- Retention of conjugated linoleic acid in the mammary gland is associated with tumor inhibition during the post-initiation phase of carcinogenesis. (1997) (129)
- Vaccenic Acid Feeding Increases Tissue Levels of Conjugated Linoleic Acid and Suppresses Development of Premalignant Lesions in Rat Mammary Gland (2001) (127)
- Conjugated linoleic acid and linoleic acid are distinctive modulators of mammary carcinogenesis. (1997) (125)
- Induction of apoptosis by conjugated linoleic acid in cultured mammary tumor cells and premalignant lesions of the rat mammary gland. (2000) (121)
- Synergy between selenium and vitamin E in apoptosis induction is associated with activation of distinctive initiator caspases in human prostate cancer cells. (2003) (119)
- Enhancement of mammary tumorigenesis by dietary selenium deficiency in rats with a high polyunsaturated fat intake. (1981) (118)
- Endoplasmic reticulum stress signal mediators are targets of selenium action. (2005) (117)
- Prevention of Mammary Cancer with Conjugated Linoleic Acid: Role of the Stroma and the Epithelium (2004) (117)
- Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates (2007) (113)
- Enhanced selenium effect on growth arrest by BiP/GRP78 knockdown in p53-null human prostate cancer cells (2006) (110)
- Fat and essential fatty acid in mammary carcinogenesis. (1987) (108)
- Enrichment of selenium in allium vegetables for cancer prevention. (1994) (98)
- Alterations in serum glycosyltransferases and 5'-nucleotidase in breast cancer patients. (1978) (98)
- Comparative effect of inorganic and organic selenocyanate derivatives in mammary cancer chemoprevention. (1994) (97)
- Milk fatty acids and human health: Potential role of conjugated linoleic acid and trans fatty acids (2006) (95)
- Factors influencing the anticarcinogenic efficacy of selenium in dimethylbenz[a]anthracene-induced mammary tumorigenesis in rats. (1981) (93)
- Tumorigenesis, metabolism, speciation, bioavailability, and tissue deposition of selenium in selenium-enriched ramps (Allium tricoccum). (2000) (92)
- Comparative effects of different animal and vegetable fats fed before and during carcinogen administration on mammary tumorigenesis, sexual maturation, and endocrine function in rats. (1986) (91)
- Inhibition of angiogenesis by the cancer chemopreventive agent conjugated linoleic acid. (2002) (90)
- Efficacy of cancer prevention by high-selenium garlic is primarily dependent on the action of selenium. (1995) (90)
- Methyl selenium metabolites decrease prostate-specific antigen expression by inducing protein degradation and suppressing androgen-stimulated transcription. (2004) (90)
- Selenium modulation of cell proliferation and cell cycle biomarkers in normal and premalignant cells of the rat mammary gland. (2000) (88)
- Methylseleninic Acid Potentiates Apoptosis Induced by Chemotherapeutic Drugs in Androgen-Independent Prostate Cancer Cells (2005) (87)
- The Chemopreventive Role of Selenium in Carcinogenesis (1986) (87)
- Isomers of conjugated linoleic acid differ in their effects on angiogenesis and survival of mouse mammary adipose vasculature. (2004) (87)
- Dietary intake of conjugated linoleic acids and risk of premenopausal and postmenopausal breast cancer, Western New York Exposures and Breast Cancer Study (WEB Study). (2004) (87)
- Monomethylated selenium inhibits growth of LNCaP human prostate cancer xenograft accompanied by a decrease in the expression of androgen receptor and prostate‐specific antigen (PSA) (2006) (84)
- Chemoprevention of mammary tumorigenesis by a combined regimen of selenium and vitamin A. (1981) (83)
- Ability of dietary fat to overcome the resistance of mature female rats to 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis. (1980) (83)
- Tissue selenium levels in selenium-supplemented rats and their relevance in mammary cancer protection. (1989) (83)
- Chemoprevention of mammary cancer with Se-allylselenocysteine and other selenoamino acids in the rat. (1999) (80)
- AMPK-mediated autophagy is a survival mechanism in androgen-dependent prostate cancer cells subjected to androgen deprivation and hypoxia. (2011) (80)
- Anticarcinogenic effect of selenium in rats treated with dimethylbenz[a]anthracene and fed different levels and types of fat. (1981) (80)
- Androgen receptor signaling intensity is a key factor in determining the sensitivity of prostate cancer cells to selenium inhibition of growth and cancer-specific biomarkers (2005) (79)
- Selenium-enriched garlic inhibits the early stage but not the late stage of mammary carcinogenesis. (1996) (77)
- Peroxiredoxin 1 interacts with androgen receptor and enhances its transactivation. (2007) (77)
- Hypoxia increases androgen receptor activity in prostate cancer cells. (2006) (75)
- Metabolites of sodium selenite and methylated selenium compounds administered at cancer chemoprevention levels in the rat. (1993) (74)
- Selenium inhibition of chemical carcinogenesis. (1985) (73)
- Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells. (2005) (72)
- A comparison of the effects of the prostaglandin synthesis inhibitors indomethacin and carprofen on 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis in rats fed different amounts of essential fatty acid. (1989) (69)
- The chemopreventive role of selenium in carcinogenesis. (1986) (69)
- The t10,c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium. (2007) (69)
- Modulation of phase I and phase II xenobiotic-metabolizing enzymes by selenium-enriched garlic in rats. (1997) (65)
- Delineating the mechanism by which selenium deactivates Akt in prostate cancer cells (2006) (65)
- Selenium disrupts estrogen signaling by altering estrogen receptor expression and ligand binding in human breast cancer cells. (2005) (65)
- Dietary vitamin E intake and mammary carcinogenesis in rats. (1982) (65)
- Characterization of tissue selenium profiles and anticarcinogenic responses in rats fed natural sources of selenium-rich products. (1994) (64)
- Serum sialyltransferase and 5'-nucleotidase as reliable biomarkers in women with breast cancer. (1980) (64)
- Role of prolactin in the promotion of dimethylbenz[a]anthracene-induced mammary tumors by dietary fat. (1980) (61)
- Methylselenocysteine modulates proliferation and apoptosis biomarkers in premalignant lesions of the rat mammary gland. (2001) (60)
- Bioactivity of selenium from Brazil nut for cancer prevention and selenoenzyme maintenance. (1994) (60)
- Similarity between trans fat and saturated fat in the modification of rat mammary carcinogenesis. (1984) (54)
- Effects of selenium on 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis and DNA adduct formation. (1985) (53)
- Detection of conjugated C16 PUFAs in rat tissues as possible partial beta-oxidation products of naturally occurring conjugated linoleic acid and its metabolites. (2004) (52)
- Control of Rat Mammary Epithelium Proliferation by Conjugated Linoleic Acid (2001) (52)
- Mammary cancer chemoprevention by inorganic and organic selenium: single agent treatment or in combination with vitamin E and their effects on in vitro immune functions. (1987) (51)
- Combination of blocking agents and suppressing agents in cancer prevention. (1991) (50)
- Survival advantage of AMPK activation to androgen-independent prostate cancer cells during energy stress. (2010) (49)
- Serum estrogens and estrogen responsiveness in 7,12-dimethylbenz[a]anthracene-induced mammary tumors as influenced by dietary fat. (1981) (49)
- Chemotherapeutic sensitization by endoplasmic reticulum stress: Increasing the efficacy of taxane against prostate cancer (2009) (47)
- High superoxide dismutase and low glutathione peroxidase activities in red blood cells predict susceptibility of lung cancer patients to radiation pneumonitis. (2007) (47)
- Efficacy of trimethylselenonium versus selenite in cancer chemoprevention and its modulation by arsenite. (1988) (46)
- Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats. (1986) (46)
- Increase in serum and tissue glycosyltransferases and glycosidases in tumor-bearing rats. (1977) (46)
- Dietary selenium intake and growth of the MT-W9B transplantable rat mammary tumor. (1981) (46)
- Androgen receptor-mTOR crosstalk is regulated by testosterone availability: implication for prostate cancer cell survival. (2010) (46)
- Differential effect of dietary methionine on the biopotency of selenomethionine and selenite in cancer chemoprevention. (1988) (45)
- Trans fatty acids and cancer. (2009) (44)
- Microarray Data Mining for Potential Selenium Targets in Chemoprevention of Prostate Cancer. (2005) (42)
- Selenium disrupts estrogen receptor α signaling and potentiates tamoxifen antagonism in endometrial cancer cells and tamoxifen-resistant breast cancer cells (2005) (41)
- Cancer chemoprevention by aliphatic selenocyanates: effect of chain length on inhibition of mammary tumors and DMBA adducts. (1995) (41)
- Quantitative assessment of fat and calorie as risk factors in mammary carcinogenesis in an experimental model. (1990) (41)
- Conjugated linoleic acid induces apoptosis of murine mammary tumor cells via Bcl-2 loss. (2007) (40)
- Prx1 Enhances Androgen Receptor Function in Prostate Cancer Cells by Increasing Receptor Affinity to Dihydrotestosterone (2009) (40)
- Triphenylselenonium and diphenylselenide in cancer chemoprevention: comparative studies of anticarcinogenic efficacy, tissue selenium levels and excretion profile. (1997) (39)
- Controversial issues of dietary fat and experimental mammary carcinogenesis. (1993) (38)
- Activities of structurally-related lipophilic selenium compounds as cancer chemopreventive agents. (1998) (37)
- Bioavailability of selenium from selenium-enriched garlic. (1993) (37)
- Current Concepts of Selenium and Mammary Tumorigenesis (1987) (37)
- Selenium and experimental cancer. (1986) (37)
- Telomerase as an Important Target of Androgen Signaling Blockade for Prostate Cancer Treatment (2010) (35)
- Potential of food modification in cancer prevention. (1994) (34)
- Thioredoxin reductase activity in rat liver is not affected by supranutritional levels of monomethylated selenium in vivo and is inhibited only by high levels of selenium in vitro. (2001) (34)
- Effects of high dietary fat on the growth and development of ovarian-independent carcinogen-induced mammary tumors in rats. (1986) (34)
- Prostate cancer cells differ in testosterone accumulation, dihydrotestosterone conversion, and androgen receptor signaling response to steroid 5α‐reductase inhibitors (2013) (34)
- Concurrent deregulation of gelsolin and cyclin D1 in the majority of human and rodent breast cancers (1999) (33)
- Feasibility of using lower doses of chemopreventive agents in a combination regimen for cancer protection. (1988) (32)
- Doxorubicin and selenium cooperatively induce fas signaling in the absence of Fas/Fas ligand interaction. (2007) (32)
- An increase in vitamin A status by the feeding of conjugated linoleic acid. (1999) (32)
- Impact of dietary conjugated linoleic acid on the oxidative stability of rat liver microsomes and skeletal muscle homogenates. (2000) (31)
- Novel Strategies in Selenium Cancer Chemoprevention Research (1994) (29)
- Methyl Selenocysteine: Single-Dose Pharmacokinetics in Men (2011) (28)
- Biological activities of trimethylselenonium as influenced by arsenite. (1992) (28)
- Attenuation of Estrogen Receptor α (ERα) Signaling by Selenium in Breast Cancer Cells via Downregulation of ERα Gene Expression (2005) (28)
- 20(S)‐protopanaxadiol‐aglycone downregulation of the full‐length and splice variants of androgen receptor (2013) (28)
- Neoplastic growth of carcinogen-treated mammary transplants as influenced by fat intake of donor and host. (1981) (27)
- Attenuation of the anticarcinogenic action of selenium by vitamin E deficiency. (1985) (26)
- Comparative effects of antioxidants on enzymes involved in glutathione metabolism. (1984) (26)
- Cell cycle arrest biomarkers in human lung cancer cells after treatment with selenium in culture. (2003) (26)
- Activation of FOXO1 is critical for the anticancer effect of methylseleninic acid in prostate cancer cells (2010) (25)
- Chemoprevention with triphenylselenonium chloride in selenium-deficient rats. (2000) (25)
- Mammary tumorigenesis and chemoprevention studies in carcinogen-treated rats (2005) (25)
- Relevance of trans fatty acids and fish oil in animal tumorigenesis studies. (1986) (25)
- The antiandrogenic effect of finasteride against a mutant androgen receptor (2011) (24)
- Evidence of a field effect associated with mammary cancer chemoprevention by methylseleninic acid. (2002) (24)
- Dietary fat and cancer (1986) (23)
- The attributes of selenium-enriched garlic in cancer prevention. (1996) (23)
- Cellular and molecular effects of alpha-tocopheryloxybutyrate: lessons for the design of vitamin E analog for cancer prevention. (2004) (21)
- The transcriptomics of de novo androgen biosynthesis in prostate cancer cells following androgen reduction (2010) (20)
- The t 10 , c 12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice overexpressing erbB 2 in the mammary epithelium (2007) (19)
- Exercise training and the differential prolactin response in male and female rats. (1989) (19)
- Effect of estradiol and prolactin on galactosyltransferase and alpha-lactalbumin activities in rat mammary gland and mammary tumor. (1978) (19)
- Activity of triphenylselenonium chloride in mammary cancer prevention. (1994) (19)
- New approaches to cancer chemoprevention with difluoromethylornithine and selenite. (1989) (18)
- Inhibition of mammary tumorigenesis by a reduction of fat intake after carcinogen treatment in young versus adult rats. (1980) (18)
- Free amino acid pools of rodent mammary tumors. (1982) (16)
- Yield of Terminal Duct Lobule Units in Normal Breast Stereotactic Core Biopsy Specimens: Implications for Biomarker Studies (2000) (16)
- Targeting the Nrf2-Prx1 Pathway with Selenium to Enhance the Efficacy and Selectivity of Cancer Therapy (2007) (16)
- Cytostasis and cancer chemoprevention: investigating the action of triphenylselenonium chloride in in vivo models of mammary carcinogenesis. (1998) (15)
- A Display Thiol-Proteomics Approach to Characterize Global Redox Modification of Proteins by Selenium: Implications for the Anticancer Action of Selenium. (2005) (15)
- Analysis of Protein Redox Modification by Hypoxia (2006) (14)
- Interaction of dietary fat and the thymus in the induction of mammary tumors by 7,12-dimethylbenz(a)anthracene. (1982) (14)
- The direct inhibitory effect of dutasteride or finasteride on androgen receptor activity is cell line specific (2013) (12)
- Temporal changes in tissue glutathione in response to chemical form, dose, and duration of selenium treatment (1991) (11)
- Attenuation of estrogen receptor alpha (ERalpha) signaling by selenium in breast cancer cells via downregulation of ERalpha gene expression. (2005) (11)
- Activity of Se‐allylselenocysteine in the presence of methionine γ‐lyase on cell growth, DNA integrity, apoptosis, and cell‐cycle regulatory molecules (2000) (11)
- Regulation of cyclic adenosine 3',5'-monophosphate in relation to growth of dimethylbenz[a]anthracene-induced mammary tumors in rats. (1980) (10)
- Neural Network‐Based Analysis of Thiol Proteomics Data in Identifying Potential Selenium Targets (2006) (9)
- Levels and 75Se-Labeling of Specific Proteins as a Consequence of Dietary Selenium Concentration in Mice and Rats (1991) (9)
- High SOD and low GPX activities in RBC predict susceptibility of lung cancer patients to radiation pneumonitis (2007) (9)
- Isomeric fatty acids and tumorigenesis: a commentary on recent work. (1985) (8)
- Modification of mammary carcinogenesis and tissue peroxidation by selenium deficiency and dietary fat. (1981) (7)
- Lack of effect of dietary fat on the growth and estrogen sensitivity of the MT-W9B transplantable mammary tumor. (1981) (7)
- Anticarcinogenic effect of selenium in the dimethylbenz(a)anthracene-induced mammary tumor model in rats (1984) (6)
- Augmented suppression of androgen receptor signaling by a combination of α‐tocopheryl succinate and methylseleninic acid (2006) (6)
- BCG-modulated mammary carcinogenesis is dependent on the schedule of immunization but is not affected by dietary fat. (1986) (6)
- Is Selenium Metabolism Necessary for Its Anticarcinogenic Activity (1989) (5)
- Changes in ornithine decarboxylase activity and polyamine levels in response to eight different forms of selenium. (1991) (5)
- The Impact of Calorie Restriction on Mammary Cancer Development in an Experimental Model (1991) (4)
- In Vitro and in Vivo Studies of Methylseleninic Acid : Evidence That a Monomethylated Selenium Metabolite Is Critical for Cancer Chemoprevention 1 (2000) (4)
- Serum and tumor sialyltransferase activities in women with breast cancer. (1986) (3)
- Selenium and carcinogenesis (1985) (3)
- Interaction of selenium deficiency and fat intake in the regulation of enzymes associated with peroxide metabolism (1983) (2)
- Workshop on individual fatty acids and cancer : proceedings of a symposium held in Washington, DC, June 4-5, 1996 (1997) (2)
- Modulation of Mammary Carcinogenesis by Eicosanoid Synthesis Inhibitors in Rats Fed High Levels of Linoleate (1991) (1)
- The anticancer effects of vaccenic acid in milk fat are due to its conversion to conjugated linoleic acid via ∆ 9-desaturase (2004) (1)
- Dietary Fat and Mammary Carcinogenesis (1986) (1)
- 498 PROSTATE CANCER CELLS DIFFER IN TESTOSTERONE ACCUMULATION, DIHYDROTESTOSTERONE CONVERSION, AND ANDROGEN RECEPTOR SIGNALING RESPONSE TO STEROID 5α-REDUCTASE INHIBITORS (2013) (1)
- Selenium and Cancer Prevention (2006) (1)
- Introduction: Prevention of Breast Cancer--Present Reality and Future Promise (2004) (1)
- 232: Activation of Androgen Receptor by Hypoxia in Prostate Cancer: Its Clinical and Biological Implications (2005) (1)
- Peering down the kaleidoscope of thiol proteomics and unfolded protein response in studying the anticancer action of selenium (2006) (1)
- 2458 : High Superoxide Dismutase (SOD) and Low Glutathione Peroxidase (GPX) Activities in Red Blood Cells (RBCs) Predict Susceptibility of Lung Cancer Patients to Radiation Pneumonitis (2006) (0)
- Tumor markers and their significance in the management of breast cancer : proceedings of a workshop held in Bethesda, Maryland, March 6, 1985 (1986) (0)
- Similarity between frans Fat and Saturated Fat in the Modification of Rat Mammary Carcinogenesis1 (2006) (0)
- Methylseleninic acid potentiates apoptosis induced by chemotherapeutic drugs in prostate cancer cells through enhancing caspase activation (2005) (0)
- Effect of Estradici and Prolactin on Galactosyltransferase and a-Lactalbumin Activities in Rat Mammary Gland and Mammary Tumor1 (2006) (0)
- Cancer Cells Hypoxia Increases Androgen Receptor Activity in Prostate (2006) (0)
- Prophylaxis of Mammary Neoplasia by Selenium Supplementation in the Initiation and Promotion Phases of Chemical Carcinogenesis1 (2006) (0)
- Dedication: Clifford W. Welsch (2005) (0)
- New leads on vitamin E succinate-induced apoptosis signaling in prostate cancer cells (2004) (0)
- Selenium-mediated inhibition of mammary carcinogenesis (1983) (0)
- Selenium decreases prostate specific antigen expression by inducing protein degradation and suppressing mRNA abundance (2004) (0)
- Failure of interventions to maintain mitochondrial function in ischemic myocardium. (1980) (0)
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