Clifford B. Saper

Clifford B. Saper's AcademicInfluence.com Rankings

Clifford B. Saper

Medical

#610

World Rank

#816

Historical Rank

Neurology

#43

World Rank

#80

Historical Rank

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Clifford B. Saper's Degrees

Masters Medicine Harvard University

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Clifford B. Saper's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Narcolepsy in orexin Knockout Mice Molecular Genetics of Sleep Regulation (1999) (2897)
Hypothalamic regulation of sleep and circadian rhythms (2005) (2373)
The sleep switch: hypothalamic control of sleep and wakefulness (2001) (1525)
Differential expression of orexin receptors 1 and 2 in the rat brain (2001) (1499)
From Lesions to Leptin Hypothalamic Control of Food Intake and Body Weight (1999) (1213)
Efferent connections of the parabrachial nucleus in the rat (1980) (1176)
The Need to Feed Homeostatic and Hedonic Control of Eating (2002) (1072)
Distributions of leptin receptor mRNA isoforms in the rat brain (1998) (1067)
A putative flip–flop switch for control of REM sleep (2006) (1065)
Sleep State Switching (2010) (1061)
Activation of Ventrolateral Preoptic Neurons During Sleep (1996) (995)
Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat (1984) (991)
Distribution of cholinergic neurons in rat brain: Demonstrated by the immunocytochemical localization of choline acetyltransferase (1983) (960)
Expression of ghrelin receptor mRNA in the rat and the mouse brain (2006) (944)
Connections of the parabrachial nucleus with the nucleus of the solitary tract and the medullary reticular formation in the rat (1990) (930)
Leptin Differentially Regulates NPY and POMC Neurons Projecting to the Lateral Hypothalamic Area (1999) (896)
Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area (1998) (863)
Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. (2007) (860)
Leptin Activates Hypothalamic CART Neurons Projecting to the Spinal Cord (1998) (796)
Efferent projections of the infralimbic cortex of the rat (1991) (767)
Leptin Regulation of Neuroendocrine Systems (2000) (755)
The &agr;2-Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects (2003) (740)
Organization of cerebral cortical afferent systems in the rat. II. Magnocellular basal nucleus (1984) (698)
Innervation of Histaminergic Tuberomammillary Neurons by GABAergic and Galaninergic Neurons in the Ventrolateral Preoptic Nucleus of the Rat (1998) (681)
Evidence for a viscerotopic sensory representation in the cortex and thalamus in the rat (1987) (679)
The central autonomic nervous system: conscious visceral perception and autonomic pattern generation. (2002) (667)
Fos Expression in Orexin Neurons Varies with Behavioral State (2001) (657)
The Rostromedial Tegmental Nucleus (RMTg), a GABAergic Afferent to Midbrain Dopamine Neurons, Encodes Aversive Stimuli and Inhibits Motor Responses (2009) (579)
Convergence of autonomic and limbic connections in the insular cortex of the rat (1982) (565)
Effect of Lesions of the Ventrolateral Preoptic Nucleus on NREM and REM Sleep (2000) (564)
The sedative component of anesthesia is mediated by GABAA receptors in an endogenous sleep pathway (2002) (557)
Expression of melanocortin 4 receptor mRNA in the central nervous system of the rat (2003) (551)
Melanopsin in cells of origin of the retinohypothalamic tract (2001) (551)
Pedunculopontine tegmental nucleus of the rat: Cytoarchitecture, cytochemistry, and some extrapyramidal connections of the mesopontine tegmentum (1987) (544)
Unraveling the central nervous system pathways underlying responses to leptin (1998) (527)
Critical Role of Dorsomedial Hypothalamic Nucleus in a Wide Range of Behavioral Circadian Rhythms (2003) (507)
The hypothalamic integrator for circadian rhythms (2005) (507)
Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. (2002) (499)
Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance (2000) (496)
Neurobiology of the Sleep-Wake Cycle: Sleep Architecture, Circadian Regulation, and Regulatory Feedback (2006) (493)
Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome. (2005) (486)
Organization of visceral and limbic connections in the insular cortex of the rat (1991) (471)
Hypothalamic Arousal Regions Are Activated during Modafinil-Induced Wakefulness (2000) (465)
A Broad Role for Melanopsin in Nonvisual Photoreception (2003) (462)
Organization of cerebral cortical afferent systems in the rat. II. Hypothalamocortical projections (1985) (459)
Afferents to the Ventrolateral Preoptic Nucleus (2002) (445)
The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms (2006) (438)
Leptin activates neurons in ventrobasal hypothalamus and brainstem. (1997) (432)
A neural mechanism for exacerbation of headache by light (2010) (428)
Reassessment of the structural basis of the ascending arousal system (2011) (407)
Schizophrenic subjects activate dorsolateral prefrontal cortex during a working memory task, as measured by fMRI (1999) (405)
Identification of Wake-Active Dopaminergic Neurons in the Ventral Periaqueductal Gray Matter (2006) (401)
Orexin (Hypocretin) Neurons Contain Dynorphin (2001) (400)
Characterization of CART neurons in the rat and human hypothalamus (2001) (396)
Midbrain dopaminergic cell loss in parkinson's disease: Computer visualization (1989) (395)
Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei. (1998) (395)
Spinal and trigeminal dorsal horn projections to the parabrachial nucleus in the rat (1985) (384)
Organization of cortical, basal forebrain, and hypothalamic afferents to the parabrachial nucleus in the rat (1990) (380)
Atriopeptins as cardiac hormones. (1985) (379)
Decreased Number of Parvalbumin and Cholinergic Interneurons in the Striatum of Individuals with Tourette Syndrome (2009) (377)
Chemical characterization of leptin‐activated neurons in the rat brain (2000) (369)
Homeostatic, circadian, and emotional regulation of sleep (2005) (363)
Atriopeptin-immunoreactive neurons in the brain: presence in cardiovascular regulatory areas. (1985) (353)
Distribution of fos‐like immunoreactivity in the rat brain following intravenous lipopolysaccharide administration (1996) (343)
Bed nucleus of the stria terminalis: Cytoarchitecture, immunohistochemistry, and projection to the parabrachial nucleus in the rat (1989) (341)
Mechanisms of CNS response to systemic immune challenge: the febrile response (1997) (331)
Neurochemical organization of the hypothalamic projection to the spinal cord in the rat (1988) (330)
Contrasting Effects of Ibotenate Lesions of the Paraventricular Nucleus and Subparaventricular Zone on Sleep–Wake Cycle and Temperature Regulation (2001) (317)
Organization of central adrenergic pathways: I. Relationships of ventrolateral medullary projections to the hypothalamus and spinal cord (1987) (309)
Medullary and spinal efferents of the pedunculopontine tegmental nucleus and adjacent mesopontine tegmentum in the rat (1988) (307)
Afferent connections of the median preoptic nucleus in the rat: Anatomical evidence for a cardiovascular integrative mechanism in the anteroventral third ventricular (AV3V) region (1983) (297)
EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses (2007) (296)
Projections of the pedunculopontine tegmental nucleus in the rat: evidence for additional extrapyramidal circuitry (1982) (294)
Intravenous lipopolysaccharide induces cyclooxygenase 2‐like immunoreactivity in rat brain perivascular microglia and meningeal macrophages (1997) (292)
Direct projections from the A5 catecholamine cell group to the intermediolateral cell column (1979) (291)
Concomitant loss of dynorphin, NARP, and orexin in narcolepsy (2005) (285)
A Proposal for a Coordinated Effort for the Determination of Brainwide Neuroanatomical Connectivity in Model Organisms at a Mesoscopic Scale (2009) (264)
Selective Activation of the Extended Ventrolateral Preoptic Nucleus during Rapid Eye Movement Sleep (2002) (261)
Ventrolateral preoptic nucleus contains sleep-active, galaninergic neurons in multiple mammalian species (2002) (253)
Descending projections from the pontine micturition center (1979) (252)
Ventromedial Preoptic Prostaglandin E2 Activates Fever-Producing Autonomic Pathways (1996) (252)
Magic peptides, magic antibodies: Guidelines for appropriate controls for immunohistochemistry (2003) (248)
Differential Rescue of Light- and Food-Entrainable Circadian Rhythms (2008) (248)
Neurochemical architecture of the human striatum (1997) (240)
Wake–sleep circuitry: an overview (2017) (238)
Reciprocal parabrachial-cortical connections in the rat (1982) (237)
Any way you cut it: A new journal policy for the use of unbiased counting methods (1996) (231)
GABAergic parafacial zone is a medullary slow–wave–sleep promoting center (2014) (229)
Recombinant adeno-associated virus vector: use for transgene expression and anterograde tract tracing in the CNS (1998) (223)
Organization of medullary adrenergic and noradrenergic projections to the periaqueductal gray matter in the rat (1992) (215)
Topographic organization of cardiovascular responses to electrical and glutamate microstimulation of the parabrachial nucleus in the rat (1992) (213)
Neural circuitry engaged by prostaglandins during the sickness syndrome (2012) (208)
Neural Circuitry of Stress-Induced Insomnia in Rats (2008) (201)
Distribution and characterization of tumor necrosis factor‐α‐like immunoreactivity in the murine central nervous system (1993) (200)
An open letter to our readers on the use of antibodies (2005) (198)
Expression of inducible cyclooxygenase mRNA in the mouse brain after systemic administration of bacterial lipopolysaccharide (1996) (196)
Colocalization of orexin a and glutamate immunoreactivity in axon terminals in the tuberomammillary nucleus in rats (2003) (188)
Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy--a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group. (2013) (187)
Role of endogenous sleep‐wake and analgesic systems in anesthesia (2008) (183)
Organization of atriopeptin‐like immunoreactive neurons in the central nervous system of the rat (1986) (182)
Cholecystokinin‐, galanin‐, and corticotropin‐releasing factor‐like immunoreactive projections from the nucleus of the solitary tract to the parabrachial nucleus in the rat (1990) (182)
Staying awake for dinner: hypothalamic integration of sleep, feeding, and circadian rhythms. (2006) (179)
The pontine REM switch: past and present (2007) (178)
Distribution and characterization of cyclooxygenase immunoreactivity in the ovine brain (1992) (177)
The biochemical pharmacology of atrial peptides. (1989) (171)
Glutamatergic Signaling from the Parabrachial Nucleus Plays a Critical Role in Hypercapnic Arousal (2013) (169)
A Guide to the Perplexed on the Specificity of Antibodies (2009) (168)
Characteristics of thermoregulatory and febrile responses in mice deficient in prostaglandin EP1 and EP3 receptors. (2003) (167)
Activation of ventrolateral preoptic neurons by the somnogen prostaglandin D2. (1998) (160)
Neuronal pathology in the nucleus basalis and associated cell groups in senile dementia of the Alzheimer's type (1985) (157)
The hypothalamus (2014) (156)
Calcitonin gene‐related peptide (CGRP) immunoreactive projections from the thalamus to the striatum and amygdala in the rat (1991) (154)
Activation of neurons projecting to the paraventricular hypothalamic nucleus by intravenous lipopolysaccharide (1996) (152)
Neuropeptide‐immunoreactive neurons projecting to the paraventricular hypothalamic nucleus in the rat (1994) (149)
Relationship of EP1‐4 prostaglandin receptors with rat hypothalamic cell groups involved in lipopolysaccharide fever responses (2000) (148)
Chapter 1 The emotional motor system (1996) (148)
Edinger-Westphal nucleus: Projections to the brain stem and spinal cord in the cat (1978) (146)
Hypothalamic pathology in Alzheimer's disease (1987) (145)
Suprachiasmatic neuron numbers and rest–activity circadian rhythms in older humans (2015) (144)
Medullary catecholamine inputs to the anteroventral third ventricular cardiovascular regulatory region in the rat (1983) (143)
A human brain network derived from coma-causing brainstem lesions (2016) (142)
Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice (2018) (140)
Organization of the facial nucleus and corticofacial projection in the monkey (1987) (139)
A neurohistochemical blueprint for pain-induced loss of appetite (2001) (136)
COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice. (2009) (134)
Lipopolysaccharide Activates Specific Populations of Hypothalamic and Brainstem Neurons That Project to the Spinal Cord (2000) (133)
Parallel Preoptic Pathways for Thermoregulation (2009) (133)
Evidence for a deficit in cholinergic interneurons in the striatum in schizophrenia (1999) (131)
Locus Ceruleus and Anterior Cingulate Cortex Sustain Wakefulness in a Novel Environment (2010) (131)
A Novel Population of Wake-Promoting GABAergic Neurons in the Ventral Lateral Hypothalamus (2016) (129)
Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer's disease. (2014) (129)
Effects of adenosine on gabaergic synaptic inputs to identified ventrolateral preoptic neurons (2003) (125)
A cytoarchitectonic and histochemical study of nucleus basalis and associated cell groups in the normal human brain (1984) (121)
Spinal projections of the A5, A6 (locus coeruleus), and A7 noradrenergic cell groups in rats (2012) (121)
Calcitonin gene‐related peptide immunoreactivity in the visceral sensory cortex, thalamus, and related pathways in the rat (1989) (120)
Re-evaluation of the efferent projections of the Edinger-Westphal nucleus in the cat (1978) (119)
The emotional motor system. (1996) (116)
Inhibition of the firing of vasopressin neurons by atriopeptin (1987) (114)
Supramammillary glutamate neurons are a key node of the arousal system (2017) (114)
Correspondence of melanin-pigmented neurons in human brain with A1-A14 catecholamine cell groups. (1982) (109)
Preservation of hypothalamic dopaminergic neurons in Parkinson's disease (1985) (109)
Adenosine inhibits basal forebrain cholinergic and noncholinergic neurons in vitro (2006) (109)
Inhibition of nitric oxide synthase produces hypothermia and depresses lipopolysaccharide fever. (1996) (109)
The central circadian timing system (2013) (107)
Brain natriuretic peptides: Differential localization of a new family of neuropeptides (1989) (104)
Neurobiological Basis of Fever (1998) (103)
A hypothalamic circuit for the circadian control of aggression (2018) (102)
Neuropeptide organization of the hypothalamic projection to the parabrachial nucleus in the rat (1990) (102)
Microinjection of a cyclooxygenase inhibitor into the anteroventral preoptic region attenuates LPS fever. (1998) (100)
Colocalization of atriopeptin-like immunoreactivity with choline acetyltransferase-and substance P-like immunoreactivity in the pedunculopontine and laterodorsal tegmental nuclei in the rat (1986) (99)
Cholecystokinin-immunoreactive innervation of the ventromedial hypothalamus in the rat: Possible substrate for autonomic regulation of feeding (1985) (98)
Specific roles of cyclooxygenase‐1 and cyclooxygenase‐2 in lipopolysaccharide‐induced fever and fos expression in rat brain (2003) (97)
Paraneoplastic cerebellar degeneration (1992) (96)
Focal Deletion of the Adenosine A1 Receptor in Adult Mice Using an Adeno-Associated Viral Vector (2003) (94)
Lateral hypothalamic innervation of the cerebral cortex: Immunoreactive staining for a peptide resembling but immunochemically distinct from pituitary/arcuate α-melanocyte stimulating hormone (1986) (94)
A Brainstem Network Mediating Apneic Reflexes in the Rat (1998) (94)
Specificity of spinal projections from hypothalamic and brainstem areas which innervate sympathetic preganglionic neurons (1985) (92)
Medullary catecholaminergic neurons in the normal human brain and in Parkinson's disease (1991) (91)
A Genetically Defined Circuit for Arousal from Sleep during Hypercapnia (2017) (91)
Fos activation in hypothalamic neurons during cold or warm exposure: Projections to periaqueductal gray matter (2005) (89)
Co-Localization of substance P- and phenylethanolamine-N-methyltransferase-like immunoreactivity in neurons of ventrolateral medulla that project to the spinal cord: Potential role in control of vasomotor tone (1985) (88)
Calcitonin gene-related peptide-like immunoreactivity marks putative visceral sensory pathways in human brain (2000) (85)
Increased fragmentation of rest-activity patterns is associated with a characteristic pattern of cognitive impairment in older individuals. (2012) (85)
The biological basis for mind body interactions (2000) (84)
Evidence for a cholinergic projection from the pedunculopontine tegmental nucleus to the rostral ventrolateral medulla in the rat (1990) (82)
Identifying the efferent projections of leptin‐responsive neurons in the dorsomedial hypothalamus using a novel conditional tracing approach (2010) (81)
Role of the Medial Prefrontal Cortex in Cataplexy (2013) (80)
Stabilization of TMB Reaction Product for electron microscopic retrograde and anterograde fiber tracing (1985) (78)
Neurofibrillary tangles in the cerebral cortex of sheep (1994) (78)
Effects of Sleep on Wake-Induced c-fos Expression (1997) (77)
Hypothalamic connections with the cerebral cortex. (2000) (77)
Melanin-concentrating hormone neurons specifically promote rapid eye movement sleep in mice (2016) (75)
Synaptic and morphological characteristics of temperature‐sensitive and ‐insensitive rat hypothalamic neurones (2001) (75)
Retinal input to the sleep-active ventrolateral preoptic nucleus in the rat (1999) (72)
Ciliary neurotrophic factor and leptin induce distinct patterns of immediate early gene expression in the brain. (2004) (71)
Gelastic epilepsy and hypothalamic hamartomas: neuroanatomical analysis of brain lesions in 100 patients. (2011) (70)
Cholinergic innervation in the human hippocampal formation including the entorhinal cortex (1994) (69)
Projections from the subparaventricular zone define four channels of output from the circadian timing system (2015) (69)
Connections of the hippocampal formation in humans: I. The mossy fiber pathway (1997) (69)
Distribution of catecholamine-containing neurons in the normal human hypothalamus (1985) (69)
The spinoparabrachial pathway: Shedding new light on an old path (1995) (68)
Anatomical Location of the Mesencephalic Locomotor Region and Its Possible Role in Locomotion, Posture, Cataplexy, and Parkinsonism (2015) (68)
Pathological changes in frontal cortex from biopsy to autopsy in Alzheimer's disease (1993) (66)
Distribution and characterization of tumor necrosis factor-alpha-like immunoreactivity in the murine central nervous system. (1993) (66)
Reciprocal Control of Drinking Behavior by Median Preoptic Neurons in Mice (2016) (66)
Effects of lesions of the histaminergic tuberomammillary nucleus on spontaneous sleep in rats. (2004) (65)
The insular cortex and cardiac response to stroke (2006) (65)
Respiratory‐related outputs of glutamatergic, hypercapnia‐responsive parabrachial neurons in mice (2015) (64)
Localization of mu-opioid receptors on amygdaloid projection neurons in the parabrachial nucleus of the rat (1999) (64)
33 – Cholinergic System (1990) (64)
Reduced Density of Cholinergic Interneurons in the Ventral Striatum in Schizophrenia: An In Situ Hybridization Study (2005) (63)
Modafinil: a drug in search of a mechanism. (2004) (61)
Quantification of the fragmentation of rest-activity patterns in elderly individuals using a state transition analysis. (2011) (60)
REM sleep behavior disorder (2003) (59)
Molecular Evolution of τ Protein: Implications for Alzheimer's Disease (1996) (59)
What optogenetic stimulation is telling us (and failing to tell us) about fast neurotransmitters and neuromodulators in brain circuits for wake–sleep regulation (2014) (55)
Central neurogenic hyperventilation: a case report and discussion of pathophysiology. (2005) (54)
Brain natriuretic peptide-like immunoreactive innervation of the cardiovascular and cerebrovascular systems in the rat. (1990) (53)
Contrasting effects of E type prostaglandin (EP) receptor agonists on core body temperature in rats (2003) (53)
Metabolic effects of chronic sleep restriction in rats. (2012) (53)
Handbook of Psychiatry in Palliative Medicine (2002) (52)
Function of the locus coeruleus (1987) (51)
Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice. (2016) (51)
Cholinergic innervation of the human cerebellum (1993) (51)
The lateral hypothalamic parvalbumin‐immunoreactive (PV1) nucleus in rodents (2012) (51)
CHOLINERGIC INNERVATION IN THE HUMAN STRIATUM: A THREE-COMPARTMENT MODEL (1996) (50)
Orexin, drugs and motivated behaviors (2005) (48)
A common polymorphism near PER1 and the timing of human behavioral rhythms (2012) (46)
Movement suppression during anesthesia: Neural projections from the mesopontine tegmentum to areas involved in motor control (2005) (44)
Connections of the hippocampal formation in humans: II. The endfolial fiber pathway (1997) (44)
Deletion of presynaptic adenosine A1 receptors impairs the recovery of synaptic transmission after hypoxia (2005) (44)
Median preoptic glutamatergic neurons promote thermoregulatory heat loss and water consumption in mice (2017) (43)
α‐synuclein pathology accumulates in sacral spinal visceral sensory pathways (2015) (42)
A Simple inexpensive and reliable nanoliter syringe (1983) (42)
Evidence for a cortical projection to the magnocellular basal nucleus in the rat: an electron microscopic axonal transport study (1985) (42)
Chapter 28 – Anatomy of the Mammalian Circadian System (2005) (42)
Focus on the pedunculopontine nucleus. Consensus review from the May 2018 brainstem society meeting in Washington, DC, USA (2019) (42)
The Consortium. (1995) (41)
Diffuse Cortical Projection Systems: Anatomical Organization and Role in Cortical Function (2011) (41)
Atriopeptin: potent hormone and potential neuromediator (1985) (41)
The Neurobiology of Sleep (2013) (38)
Plum and Posner's Diagnosis and Treatment of Stupor and Coma (2019) (37)
Ultrastructure of neurofibrillary tangles in the cerebral cortex of sheep (1995) (37)
In living color (2007) (37)
Neural Circuitry Underlying Waking Up to Hypercapnia (2019) (37)
EP3R-Expressing Glutamatergic Preoptic Neurons Mediate Inflammatory Fever (2020) (36)
Stabilization of the Tetramethylbenzidine (TMB) Reaction Product (1984) (35)
Pain as a visceral sensation. (2000) (35)
The ventrolateral preoptic nucleus is not required for isoflurane general anesthesia (2011) (35)
A Glutamatergic Hypothalamomedullary Circuit Mediates Thermogenesis, but Not Heat Conservation, during Stress-Induced Hyperthermia (2018) (34)
Orexins: looking forward to sleep, back at addiction (2007) (34)
CHAPTER 24 – Central Autonomic System (2004) (34)
Molecular evolution of tau protein: implications for Alzheimer's disease. (1996) (33)
Alz-50 immunohistochemistry in the normal sheep striatum: a light and electron microscope study (1993) (33)
A translational approach to capture gait signatures of neurological disorders in mice and humans (2017) (32)
Microinjection of a cyclooxygenase inhibitor into the anteroventral preoptic region attenuates LPS fever. (1998) (29)
Role of the cerebral cortex and striatum in emotional motor response. (1996) (28)
Perspectives on the rapid eye movement sleep switch in rapid eye movement sleep behavior disorder. (2013) (27)
Impaired Circadian Photosensitivity in Mice Lacking Glutamate Transmission from Retinal Melanopsin Cells (2015) (27)
Chemical Neuroanatomy of Alzheimer’s Disease (1988) (27)
Response to Comment on "Differential Rescue of Light- and Food-Entrainable Circadian Rhythms" (2008) (26)
REM sleep behavior disorder (2006) (26)
Reassessing the Role of Histaminergic Tuberomammillary Neurons in Arousal Control (2019) (25)
Differential distribution of AMPA-selective glutamate receptor subunits in the parabrachial nucleus of the rat (1995) (24)
The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep (2015) (24)
The House Alarm. (2016) (24)
Inducible clocks: living in an unpredictable world. (2007) (24)
Is there even such a thing as “Idiopathic normal pressure hydrocephalus”? (2017) (24)
Critical Dynamics and Coupling in Bursts of Cortical Rhythms Indicate Non-Homeostatic Mechanism for Sleep-Stage Transitions and Dual Role of VLPO Neurons in Both Sleep and Wake (2019) (24)
The Dance of the Perivascular and Endothelial Cells: Mechanisms of Brain Response to Immune Signaling (2010) (23)
Is Food-Directed Behavior an Appropriate Measure of Circadian Entrainment to Restricted Daytime Feeding? (2007) (23)
Efferent connections of the parvalbumin‐positive (PV1) nucleus in the lateral hypothalamus of rodents (2013) (23)
Connectivity of sleep- and wake-promoting regions of the human hypothalamus observed during resting wakefulness (2018) (22)
Regulation of hippocampal dendritic spines following sleep deprivation (2020) (22)
Unbiased Stereology: Three-Dimensional Measurement in Microscopy by C.V. Howard and M.G. Reed (1999) (21)
Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals (2020) (20)
Prostaglandin E2 Attenuates Preoptic Expression of GABAA Receptors via EP3 Receptors* (2008) (19)
Counting on our reviewers to set the standards (1997) (18)
Sleep, circadian rhythms, and dementia (2011) (17)
Lateral hypothalamic acetylcholinesterase-immunoreactive neurons co-express either orexin or melanin concentrating hormone (2004) (17)
Chapter V The cholinergic system in the primate brain: basal forebrain and pontine-tegmental cell groups (1997) (16)
Standards of evidence in chronobiology: A response (2009) (16)
Atriopeptin: neuromediator in the central regulation of cardiovascular function (1988) (16)
Emerging therapeutics in sleep (2013) (15)
'Like a thief in the night': the selectivity of degeneration in Parkinson's disease. (1999) (14)
CHAPTER 17 – Hypothalamus (2004) (14)
Leukemic infiltration of the cerebellum in acute myelomonocytic leukemia (1982) (14)
Flipping the switch on the body’s thermoregulatory system (2020) (14)
Long‐term synaptic plasticity is impaired in rats with lesions of the ventrolateral preoptic nucleus (2009) (14)
The rostromedial tegmental nucleus ( RMTg ) , a major GABAergic afferent to midbrain dopamine neurons , selectively encodes aversive stimuli and promotes behavioral inhibition (2010) (13)
Chapter 16 – Hypothalamus (2012) (13)
Chronic motor axonal neuropathy: Pathological evidence of inflammatory polyradiculoneuropathy (1999) (13)
The Emperor has no clothes (2016) (13)
Injections of okadaic acid, but not beta-amyloid peptide, induce Alz-50 immunoreactive dystrophic neurites in the cerebral cortex of sheep (1996) (11)
Pathophysiology of Signs and Symptoms of Coma (2008) (10)
“All fall down”: The mechanism of orthostatic hypotension in multiple systems atropy and Parkinson's disease (1998) (10)
Multimodal anesthesia and systems neuroscience: the new frontier. (2008) (9)
Jason W (2006) (9)
Erratum: Expression of ghrelin receptor mRNA in the rat and the mouse brain (Journal of Comparative Neurology 494 (528-548)) (2006) (9)
Academic publishing, part III: How to write a research paper (so that it will be accepted) in a high‐quality journal (2015) (9)
Multifocal, Diffuse, and Metabolic Brain Diseases Causing Delirium, Stupor, or Coma (2008) (9)
How low can you go? (2015) (8)
Image is Everything (1999) (8)
Commentaries on Viewpoint: Central chemoreception is a complex system function that involves multiple brain stem sites. (2009) (8)
Orexin neurons inhibit sleep to promote arousal (2022) (8)
Role of the median preoptic nucleus in the autonomic response to heat-exposure* (2018) (8)
Armodafinil-induced wakefulness in animals with ventrolateral preoptic lesions (2014) (8)
Neurobiology of Insomnia (2005) (8)
Functional Anatomical Analysis of Respiratory Circuitry (2002) (7)
Animal behaviour: The nexus of sex and violence (2011) (7)
Passages: 1994–1995 (1995) (7)
The Neuroscience Peer Review Consortium (2009) (6)
Genetic identification of preoptic neurons that regulate body temperature in mice (2021) (6)
Commentary on: Efferent connections of the parabrachial nucleus in the rat. C.B. Saper and A.D. Loewy, Brain Research 197:291–317, 1980 (2016) (6)
Activation of Ventrolateral Preoptic Neurons During Sleep (Reports) (1996) (6)
Characteristics of thermoregulatory and febrile responses in mice deficient in prostaglandin EP1 and EP3 receptors (2003) (6)
The value of alternative morphological approaches to alzheimer's disease (1987) (6)
Biology of sleep and circadian rhythms in the neurology resident (2015) (5)
Life, the Universe, and Body Temperature (2006) (5)
Clinical case conference: A 41‐year‐old woman with progressive weakness and sensory loss (2014) (5)
Brain natriuretic peptide-like immunoreactive innervation of the cerebrovascular system in the rat. (1990) (5)
Restoration: Potential for compensatory changes in numbers of neurons in adult human brain (2013) (5)
Examination of the Comatose Patient (2008) (5)
Up in smoke: A neurologist's approach to “medical marijuana” (2015) (5)
Progress in Epilepsy Research (1998) (5)
The agony of the ecstasy (2009) (5)
New perspectives on circadian rhythms and sleep (2013) (5)
Special issue: The anatomy of the soul (2005) (4)
Somatosympathetic reflex unilateral sweating and pupillary dilatation in a paraplegic man (1986) (4)
Short and Sweet (2015) (4)
Academic publishing, part II: Where to publish your work (2014) (4)
Of hearts and minds: Natriuretic peptides in the brain (1995) (4)
The intermediate nucleus in humans: Cytoarchitecture, chemoarchitecture, and relation to sleep, sex, and Alzheimer disease. (2021) (4)
Reassessment of the structural basis of the ascending arousal system (4)
Homage to Sanford L. Palay, M.D. Editor‐in‐Chief, 1980–1993 (1996) (4)
Hypothalamic Dysfunction Without Hamartomas Causing Gelastic Seizures in Optic Nerve Hypoplasia (2015) (4)
Commentary on: Saper CB, Loewy AD, Swanson LW, Cowan WM. (1976) Direct hypothalamo-autonomic connections. Brain Research 117:305–312 (2016) (3)
Approach to Management of the Unconscious Patient (2008) (3)
Prognosis in Coma and Related Disorders of Consciousness, Mechanisms Underlying Outcomes, and Ethical Considerations (2008) (3)
Origin of porcine brain natriuretic peptide-like immunoreactive innervation of the middle cerebral artery in the rat (1991) (3)
Why “Medicare for All” would be a disaster (2019) (3)
The Neuroscience Peer Review Consortium (2008) (3)
Chronic circadian disruption on a high-fat diet impairs glucose tolerance. (2022) (3)
Enhanced appetitive discrimination learning in rats treated with α-methyltyrosine (2004) (3)
Academic publishing, part I: Peering into the review process (2014) (3)
Brain Circuitry for Arousal from Apnea. (2019) (3)
The importance of being earnest: The role of industry employees in studies about their products (2014) (3)
Structural Causes of Stupor and Coma (2008) (3)
The Neuroscience Peer Review Consortium (2009) (3)
The great depression of biomedical science (2014) (2)
The Neuroscience Peer Review Consortium (2009) (2)
Role of Calcitonin-Gene-Related Peptide (CGRP) as a Chemical Marker for the Thalamocortical Visceral Sensory System (1994) (2)
Leptin regulates NPY and MCH immunoreactivities in the mouse brain (1997) (2)
Median preoptic GABA and glutamate neurons exert differential control over sleep behavior (2022) (2)
Hypothalamic Hamartomas (2021) (2)
Symptomatic Hydrocephalus with Normal Cerebrospinal Pressure and Alzheimer's Disease (2020) (2)
Corrigendum to “Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy—a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group” [Sleep Med 14(8) (2013) 795–806] (2014) (2)
Corrigendum: Orexin, drugs and motivated behaviors (2005) (2)
The Neuroscience Peer Review Consortium (2009) (2)
Passing a small-bore nasogastric feeding catheter. (1980) (1)
The search for thermoregulatory neurons is heating up. (2021) (1)
0117 GENETIC DISSECTION OF NEURAL PATHWAYS INVOLVED IN REM SLEEP REGULATION BY MELANIN-CONCENTRATING HORMONE NEURONS (2017) (1)
Limitations of morphological studies in human brain: Opportunities for studies in nonhuman primates (1993) (1)
No place for secrets in scientific research (2006) (1)
The role of adenosine A1 receptors in sleep and behavioral arousal; focal gene deletion using the Cre-loxP system (2002) (1)
Corrigendum: The GABAergic parafacial zone is a medullary slow wave sleep–promoting center (2014) (1)
Book ReviewLocalization in Clinical Neurology (1985) (1)
Which came first, the neuritic plaque or the neurofibrillary tangle? (1986) (1)
Major advances in sleep neurology: 2002–22 (2022) (1)
Evolving Understanding and Management (1)
Reply to is there even such a thing as “idiopathic normal pressure hydrocephalus”? (2017) (1)
Schizophrenics are not hypofrontal on a working memory task as measured by fMRI (1998) (1)
Weighed and Measured (2014) (1)
VISCERAL SENSATION AND VISCERAL SENSORY DISORDERS (2007) (1)
Book Review The Psychoses of Epilepsy By Michael R. Trimble. 210 pp., illustrated. New York, Raven Press, 1991. $62. (1991) (1)
A Human Brain Network Linking Arousal to Awareness (S35.004) (2015) (1)
You can quote me on this… (2016) (1)
MR spectroscopy in translational neuroscience (2010) (1)
Human Brainstem and Cerebellum Atlas: Chemoarchitecture and Cytoarchitecture Paired to MRI (2022) (1)
The Affordable Care Act…or Is It? (2015) (1)
Progress in Brain Research. (1996) (1)
Remembrance of Things Past: A Critical Step in Changing our Future (2021) (1)
0065 Serotonergic Dorsal Raphe Neurons and the Neuronal Circuit for the Hypercapnia Induced Arousal (2018) (1)
Clinical problem-solving: diagnosis of tuberculous meningitis. (1999) (1)
On not-so-simple tests of simple hypotheses: A commentary on the review and model system by de lacoste and white (1993) (1)
Mice deficient in prostaglandin EP3 receptors do not induce fever but produce psychological stress-induced rise in core temperature (2003) (1)
Neuronal Mechanisms of REM Sleep and their Role in REM Sleep Behavior Disorder (2011) (1)
Mechanisms of homeostatically regulated behaviors (2013) (1)
FoxP2 cells in the lateral parabrachial area may drive respiratory responses to hypercapnia (2021) (1)
Genetic dissection of neural circuitry regulating behavioral state using conditional transgenics (2011) (1)
Forward into our next century—A letter from the editor‐in‐chief to the readers of the Journal of Comparative Neurology (1994) (1)
Book Review Basic Neurology Second edition. By John Gilroy. 423 pp., illustrated. New York, Pergamon Press, 1990. $49.50 (cloth); $29.50 (paper) (1991) (0)
Passages: 2006 (2005) (0)
Optogenetic stimulation of distinct populations of anterior preoptic neurons reveals a locus for the reciprocal control of thirst (2016) (0)
Passages 2009 changing an institution: Refocusing JCN on systems neuroscience (2009) (0)
0156 Ascending Projections of Identified Neuronal Subpopulations of the Supramammillary Hypothalamus (2018) (0)
Faculty Opinions recommendation of Transplanted hypothalamic neurons restore leptin signaling and ameliorate obesity in db/db mice. (2011) (0)
The Journal of Comparative Neurology, Table of Content, Vol. 526, No. 1, January 1, 2018 (2017) (0)
The neurophysiology of the cerebral cortex. By Lynn Bindman and Olof Lippold Austin, University of Texas Press, 1981 495 pp, illustrated, $85.00 (1983) (0)
The view from here: The eighth year of RomneyCare (2014) (0)
Passages: 2003 (2002) (0)
Flipping the switch on the body’s thermoregulatory system (2020) (0)
Message from the incoming editor (2013) (0)
The Neuroscience Peer Review Consortium (2009) (0)
Message from the incoming editor (2013) (0)
A hypothalamic circuit for the circadian control of aggression (2018) (0)
Passages: 1997 (0)
Prognosis in Coma and Related Disorders of Consciousness and Mechanisms Underlying Outcomes (2019) (0)
A treasure trove of gene expression patterns (2010) (0)
Book ReviewMedical Therapy of Acute Stroke (1989) (0)
Psychogenic Unresponsiveness (2019) (0)
What's in a name? (2015) (0)
0148 Serotonergic Dorsal Raphe Neurons Regulate Hypercapnia Induced Arousal Through 5HT2A Receptors on the Parabrachial Neurons (2020) (0)
The Journal of Comparative Neurology, Table of Content, Vol. 526, No. 4, March 1, 2018 (2018) (0)
This Week in The Journal (2020) (0)
The Neuroscience Peer Review Consortium (2009) (0)
In memoriam: William M. Landau, MD (2018) (0)
Nicotine addiction in young people. (1995) (0)
0045 Circadian Circuitry for Behavioral Aggression and its Implications for Sundowning in Dementia and Alzheimer’s Disease (2018) (0)
A word to our authors (2014) (0)
Brain Death (2019) (0)
Book ReviewBasic Neuroscience: Anatomy and physiology (1987) (0)
Relationship of motor symptoms to intellectual deficits in PD (1983) (0)
Specific Causes of Structural Coma (2008) (0)
Reply to “Medicare for All?” (2019) (0)
Cortical innervation of forehead (1988) (0)
Transition‐1997 (0)
Reply to Letter (2015) (0)
Introduction to the Topic (2017) (0)
Human Sleep- and Wake-Promoting Networks Are Anticorrelated (S13.005) (2016) (0)
Identifying specific populations of preoptic thermoregulatory neurons: The way forward (2022) (0)
The Seeds of Our Own Destruction (2010) (0)
Reply: To PMID 24942598. (2015) (0)
STATE TRANSITION ANALYSIS TO QUANTIFY REST-ACTIVITY IN THE ELDERLY (2011) (0)
Rationalizing funding of graduate medical education (2014) (0)
In memoriam: Sanford L. Palay, M.D., Editor‐In‐Chief, 1980‐1993 (2003) (0)
Supramammillary glutamate neurons are a key node of the arousal system (2017) (0)
The role of the hypothalamus in sleep regulation (2000) (0)
Corrigendum (0)
Glutamatergic Neurons in the Dorsal Hypothalamic Area Dissociate Thermogenesis from Heat Conserving Pathways During Stress Responses (2017) (0)
Reply to Drs. Halperin, Gronseth, and Gloss. (2016) (0)
Neuroendocrinologies Membership of the Neuroscience Peer Review Consortium (2009) (0)
Goodbye to Edward G. (Ted) Jones, MD, DPhil, 1939‐2011 (2011) (0)
Management of Frequently Encountered Causes of Unconsciousness (2019) (0)
Channel Contribution to Excitability Biophysical Characterization of Rat Caudal Hypothalamic Neurons: Calcium (2008) (0)
029 Median preoptic dual control over sleep regulation (2021) (0)
Channel Contribution to Excitability Biophysical Characterization of Rat Caudal Hypothalamic Neurons: Calcium (2008) (0)
What is quality in medical care? (2015) (0)
Diabetes NSF: Standard 8 - hospital admission (2004) (0)
Reply (2015) (0)
The Neuroscience Peer Review Consortium (2009) (0)
Opening up the JCN toolbox (2009) (0)
Minding the mind. (1999) (0)
The Prehistory of Orexin/Hypocretin and Melanin-Concentrating Hormone Neurons of the Lateral Hypothalamus (2011) (0)
Past as prelude: The central nervous system of vertebrates (1999) (0)
The somnogen PGD2 induces FOS expression within unique populations of sleep-active neurons (1998) (0)
0160 WAKE PROMOTION BY SUPRAMAMMILLARY NITRIC OXIDE NEURONS CRITICALLY DEPENDS ON GLUTAMATE RELEASE (2017) (0)
The Neuroscience Peer Review Consortium (2009) (0)
Annals policy on deceptive disclosure of conflicts of interest (2014) (0)
Book ReviewBrain Aging: Neuropathology and neuropharmacology (1983) (0)
A translational approach to capture gait signatures of neurological disorders in mice and humans (2017) (0)
Your Questions Answered: INSOMNIA (2006) (0)
CHAPTER 15 – The Differential Role of Prostaglandin E2 Receptors in the CNS Response to Systemic Immune Challenge (2007) (0)
Passages: 2005 (0)
Cytoarchitectonic cytochemical features of the nucleus tegmenti pedunculopontinus in the rat are distinct from extrapyramidal projections to the mesopontine tegmentum (1985) (0)
The Neuroscience Peer Review Consortium (2009) (0)
Reminiscence (2003) (0)
JCN at 500 (2007) (0)
What Are the Odds? (2020) (0)
Role of Atriopeptin in Central Cardiovascular Control (1988) (0)
Feeding ? Is Food-Directed Behavior an Appropriate Measure of Circadian Entrainment to Restricted Daytime (2007) (0)
Passages 1999: Evolution of a journal (1999) (0)
A changing of the guard (2016) (0)
Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice (2018) (0)
W. Maxwell Cowan, M.B.B.Ch., D. Phil. 1932–2002 (2003) (0)
0123 A CIRCUIT FOR THE CIRCADIAN CONTROL OF AGGRESSION (2017) (0)
Is it time to reconsider the classic neurological examination? (2018) (0)
Effect of lesionsof the ventrolateral preoptic nucleus on water maze performance (2005) (0)
activities in anesthetized but not conscious rats neurons suppresses genioglossus and diaphragm Inhibition of serotonergic medullary raphe obscurus (2015) (0)
An open letter to those who write dean's letters (2016) (0)
Passages: 1998 (0)
Initial Management of Patients with Stupor and Coma (2019) (0)
Metabolic and Diffuse Encephalopathies: Disruption of the Internal Milieu (2019) (0)
Passages 2018 (2018) (0)
The Journal of Comparative Neurology, Table of Content, Vol. 526, No. 7, May 1, 2018 (2018) (0)
Identification of preoptic neurons that generate a fever response (2021) (0)
Reply (2016) (0)
Erratum: A neurohistochemical blueprint for pain-induced loss of appetite (Proceedings of the National Academy of Sciences of the United States of America (August 14, 2001) 98: 17 (9930-9935)) (2001) (0)
Inducible clocks: Food entrainment of circadian rhythms (2007) (0)
Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals (2020) (0)
0141 DORSAL RAPHE SEROTONINERGIC NEURONS ARE PART OF THE NEURONAL CIRCUITRY REGULATING CO2 - INDUCED AROUSALS (2017) (0)
The Neuroscience Peer Review Consortium (2010) (0)
Prefrontal cortex activation in schizophrenia is related to response accuracy on a working memory task as measured by fMRI (1997) (0)

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What Schools Are Affiliated With Clifford B. Saper?

Clifford B. Saper is affiliated with the following schools:

University of Chicago