Clifford John Steer
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(Suggest an Edit or Addition)Clifford John Steer's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Molecular mechanisms of hepatocellular carcinoma (2008) (609)
- A guiding map for inflammation (2017) (402)
- The role of p53 in apoptosis. (2010) (327)
- Ursodeoxycholic Acid May Inhibit Deoxycholic Acid-Induced Apoptosis by Modulating Mitochondrial Transmembrane Potential and Reactive Oxygen Species Production (1998) (323)
- Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states (2009) (315)
- Bile acids: regulation of apoptosis by ursodeoxycholic acid (2009) (291)
- Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease (2002) (283)
- Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation (1999) (255)
- Similar Patterns of Mitochondrial Vulnerability and Rescue Induced by Genetic Modification of α-Synuclein, Parkin, and DJ-1 in Caenorhabditis elegans* (2005) (252)
- In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides (1998) (250)
- Cellular and molecular mechanisms of hepatocellular carcinoma: an update (2013) (206)
- MicroRNA‐143 reduces viability and increases sensitivity to 5‐fluorouracil in HCT116 human colorectal cancer cells (2009) (196)
- MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis (2009) (195)
- Studies on a mammalian hepatic binding protein specific for asialoglycoproteins. Evidence for receptor recycling in isolated rat hepatocytes. (1980) (194)
- Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide. (1999) (191)
- Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats (2003) (189)
- Uptake and distribution of placental glucocerebrosidase in rat hepatic cells and effects of sequential deglycosylation. (1981) (177)
- miR-34a Regulates Mouse Neural Stem Cell Differentiation (2011) (176)
- Image averaging of flexible fibrous macromolecules: the clathrin triskelion has an elastic proximal segment. (1991) (168)
- MicroRNA-21 is a potential link between non-alcoholic fatty liver disease and hepatocellular carcinoma via modulation of the HBP1-p53-Srebp1c pathway (2015) (157)
- MicroRNAs as gatekeepers of apoptosis (2010) (156)
- miRNA Expression in Colon Polyps Provides Evidence for a Multihit Model of Colon Cancer (2011) (150)
- Gene networks and microRNAs implicated in aggressive prostate cancer. (2009) (148)
- The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases (2014) (147)
- Neuroprotection by a Bile Acid in an Acute Stroke Model in the Rat (2002) (141)
- Inhibition of microRNA‐24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia (2014) (134)
- Tumor-stromal cross talk: direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes. (2014) (134)
- Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma. (2012) (133)
- Dietary selenium affects methylation of the wobble nucleoside in the anticodon of selenocysteine tRNA([Ser]Sec). (1993) (127)
- Changes in Colonic Bile Acid Composition following Fecal Microbiota Transplantation Are Sufficient to Control Clostridium difficile Germination and Growth (2016) (115)
- A Bile Acid Protects against Motor and Cognitive Deficits and Reduces Striatal Degeneration in the 3-Nitropropionic Acid Model of Huntington's Disease (2001) (113)
- Developmental regulation of CRD-BP, an RNA-binding protein that stabilizes c-myc mRNA in vitro (1997) (110)
- Nucleotide Exchange in Genomic DNA of Rat Hepatocytes Using RNA/DNA Oligonucleotides (1999) (110)
- Tauroursodeoxycholic Acid Prevents Amyloid-β Peptide-Induced Neuronal Death Via a Phosphatidylinositol 3-Kinase-Dependent Signaling Pathway (2003) (109)
- Tauroursodeoxycholic Acid Partially Prevents Apoptosis Induced by 3‐Nitropropionic Acid (2000) (109)
- Mature hepatocytes exhibit unexpected plasticity by direct dedifferentiation into liver progenitor cells in culture (2012) (106)
- Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice. (2009) (104)
- Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease. (2008) (102)
- Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome C release in isolated mitochondria. (2003) (100)
- MicroRNA-378 promotes hepatic inflammation and fibrosis via modulation of the NF-κB-TNFα pathway. (2019) (94)
- Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid. (2010) (93)
- Efficient recovery of proteins from multiple source samples after trizol® or trizol®LS RNA extraction and long-term storage (2013) (91)
- Unique distribution of glycoprotein receptors on parenchymal and sinusoidal cells of rat liver. (1979) (91)
- Tool from ancient pharmacopoeia prevents vision loss. (2006) (90)
- Tauroursodeoxycholic Acid Improves the Survival and Function of Nigral Transplants in a Rat Model of Parkinson's Disease (2002) (88)
- Regulation of Heme Oxygenase-1 Protein Expression by miR-377 in Combination with miR-217* (2010) (87)
- Safety, Tolerability, and Cerebrospinal Fluid Penetration of Ursodeoxycholic Acid in Patients With Amyotrophic Lateral Sclerosis (2010) (87)
- Ursodeoxycholic Acid Inhibits Clostridium difficile Spore Germination and Vegetative Growth, and Prevents the Recurrence of Ileal Pouchitis Associated With the Infection (2016) (86)
- Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells (2016) (86)
- Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease (2010) (85)
- Detection of membrane cholesterol by filipin in isolated rat liver coated vesicles is dependent upon removal of the clathrin coat (1984) (85)
- Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells. (2014) (85)
- The uptake of native and desialylated glucocerebrosidase by rat hepatocytes and Kupffer cells. (1978) (85)
- Inhibition of the E2F‐1/p53/Bax pathway by tauroursodeoxycholic acid in amyloid β‐peptide‐induced apoptosis of PC12 Cells (2004) (81)
- p53 Is a Key Molecular Target of Ursodeoxycholic Acid in Regulating Apoptosis* (2007) (81)
- Genome-Wide Transcriptional Profiling Reveals MicroRNA-Correlated Genes and Biological Processes in Human Lymphoblastoid Cell Lines (2009) (79)
- Apoptosis-associated microRNAs are modulated in mouse, rat and human neural differentiation (2010) (79)
- Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction (2018) (78)
- Genomewide microRNA down‐regulation as a negative feedback mechanism in the early phases of liver regeneration (2011) (74)
- Tauroursodeoxycholic acid modulates p53‐mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells (2006) (74)
- Hepatic recognition and catabolism of serum glycoproteins. (1981) (74)
- Neuronal Loss in the Rostral Ventromedial Medulla in a Rat Model of Neuropathic Pain (2011) (73)
- Ursodeoxycholic Acid Modulates E2F-1 and p53 Expression through a Caspase-independent Mechanism in Transforming Growth Factor β1-induced Apoptosis of Rat Hepatocytes* (2003) (71)
- Chemotherapy-Induced Tunneling Nanotubes Mediate Intercellular Drug Efflux in Pancreatic Cancer (2018) (69)
- Clathrin-induced pH-dependent fusion of phosphatidylcholine vesicles. (1983) (68)
- Intracellular trafficking of proteins (1991) (67)
- Posttranscriptional regulation of gene expression in liver regeneration: role of mRNA stability (1996) (65)
- Administration of tauroursodeoxycholic acid (TUDCA) reduces apoptosis following myocardial infarction in rat. (2007) (64)
- Dose-dependent differential mRNA target selection and regulation by let-7a-7f and miR-17-92 cluster microRNAs (2012) (63)
- Polylysine induces pH-dependent fusion of acidic phospholipid vesicles: a model for polycation-induced fusion. (1986) (63)
- The therapeutic effects of ursodeoxycholic acid as an anti-apoptotic agent (2001) (63)
- Mature microRNAs identified in highly purified nuclei from HCT116 colon cancer cells (2010) (62)
- Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference. (2005) (61)
- MicroRNA-206 prevents hepatosteatosis and hyperglycemia by facilitating insulin signaling and impairing lipogenesis (2016) (61)
- Gene repair using chimeric RNA/DNA oligonucleotides. (1999) (60)
- Targeting the p53 pathway of apoptosis. (2010) (60)
- The Bile Acid Tauroursodeoxycholic Acid Modulates Phosphorylation and Translocation of Bad via Phosphatidylinositol 3-Kinase in Glutamate-Induced Apoptosis of Rat Cortical Neurons (2004) (60)
- Combinatorial Treatment of DNA and Chromatin-Modifying Drugs Cause Cell Death in Human and Canine Osteosarcoma Cell Lines (2012) (60)
- Ethanol inhibits liver regeneration in rats without reducing transcripts of key protooncogenes. (1990) (56)
- Sequential expression of miR‐182 and miR‐503 cooperatively targets FBXW7, contributing to the malignant transformation of colon adenoma to adenocarcinoma (2014) (56)
- A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver (2008) (56)
- Effect of ethanol on polyamine synthesis during liver regeneration in rats. (1990) (55)
- Double-stranded siRNA targeted to the huntingtin gene does not induce DNA methylation. (2004) (55)
- Sp1-mediated transcriptional activation of miR-205 promotes radioresistance in esophageal squamous cell carcinoma (2016) (54)
- Gene Repair and Transposon‐Mediated Gene Therapy (2002) (52)
- Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53. (2007) (51)
- Apoptosis and the liver: A mechanism of disease, growth regulation, and carcinogenesis (1999) (50)
- Modulation of nuclear steroid receptors by ursodeoxycholic acid inhibits TGF-beta1-induced E2F-1/p53-mediated apoptosis of rat hepatocytes. (2004) (50)
- Trimeric binding of the 70-kD uncoating ATPase to the vertices of clathrin triskelia: a candidate intermediate in the vesicle uncoating reaction (1989) (50)
- MicroRNA‐206 prevents the pathogenesis of hepatocellular carcinoma by modulating expression of met proto‐oncogene and cyclin‐dependent kinase 6 in mice (2017) (44)
- Caspases and p53 modulate FOXO3A/Id1 signaling during mouse neural stem cell differentiation (2009) (43)
- Long‐term reduction of jaundice in Gunn rats by nonviral liver‐targeted delivery of Sleeping Beauty transposon (2009) (43)
- Clathrin-coated vesicles from rat liver: enzymatic profile and characterization of ATP-dependent proton transport. (1984) (43)
- Game and players: mitochondrial apoptosis and the therapeutic potential of ursodeoxycholic acid. (2007) (41)
- Selective hepatic uptake of human beta-hexosaminidase A by a specific glycoprotein recognition system on sinusoidal cells. (1979) (41)
- Haptoglobin and albumin synthesis in isolated rat hepatocytes. Response to potential mediators of the acute-phase reaction. (1981) (41)
- p53 and the regulation of hepatocyte apoptosis: implications for disease pathogenesis. (2009) (40)
- One Medicine One Science: a framework for exploring challenges at the intersection of animals, humans, and the environment (2014) (39)
- Cellular and Molecular Networking Within the Ecosystem of Cancer Cell Communication via Tunneling Nanotubes (2018) (39)
- Differential regulation of cyclin D1 and cell death by bile acids in primary rat hepatocytes. (2007) (39)
- Hepatic differentiation of porcine induced pluripotent stem cells in vitro. (2012) (39)
- A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acid. (2005) (38)
- Hepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease (2016) (38)
- Modulation of hepatocyte apoptosis: cross-talk between bile acids and nuclear steroid receptors. (2006) (37)
- Metabolism of Intact and Desialylated α1-Antitrypsin (1978) (36)
- Intercellular Transfer of Oncogenic KRAS via Tunneling Nanotubes Introduces Intracellular Mutational Heterogeneity in Colon Cancer Cells (2019) (36)
- Mitochondria isolated from liver contain the essential factors required for RNA/DNA oligonucleotide-targeted gene repair. (2001) (35)
- H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice (2014) (35)
- Molecular size of the hepatic receptor for asialoglycoproteins determined in situ by radiation inactivation. (1981) (35)
- Apoptosis in Transgenic Mice Expressing the P301L Mutated Form of Human Tau (2008) (34)
- microRNAs in Mitochondria: An Unexplored Niche. (2015) (34)
- Circulating microRNAs as biomarkers: A new frontier in diagnostics (2012) (34)
- Gene therapy as an alternative to liver transplantation (2002) (33)
- Imaging Tunneling Membrane Tubes Elucidates Cell Communication in Tumors. (2017) (32)
- Transmembrane orientation of the mannose 6-phosphate receptor in isolated clathrin-coated vesicles. (1985) (32)
- Infrared spectroscopic study of the pH-dependent secondary structure of brain clathrin (1984) (30)
- A negative feedback loop between microRNA-378 and Nrf1 promotes the development of hepatosteatosis in mice treated with a high fat diet. (2018) (30)
- Clathrin‐Coated Pits and Coated Vesicles: Functional and Structural Studies (2007) (29)
- MicroRNA-206 Prevents the Pathogenesis of Hepatocellular Carcinoma Via Modulating Expression of cMet and Cdk 6 (2017) (29)
- Interaction of liver clathrin coat protein with lipid model membranes. (1982) (29)
- Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition (2010) (29)
- Applicability of agarose gel electrophoresis to the physical characterization of clathrin-coated vesicles. (1985) (29)
- Ethanol interferes with regeneration‐associated changes in biotransforming enzymes: A potential mechanism underlying ethanol's carcinogenicity? (1991) (29)
- Synthesis and Biological Evaluation of Bile Acid Analogues Inhibitory to Clostridium difficile Spore Germination. (2017) (28)
- Molecular Regulation of Liver Regeneration a (1997) (28)
- Hepatic differentiation of liver‐derived progenitor cells and their characterization by microRNA analysis (2010) (28)
- Erythroid-specific expression of beta-globin by the sleeping beauty transposon for Sickle cell disease. (2007) (28)
- Liver‐targeted gene therapy: Approaches and challenges (2015) (26)
- Evaluation of a new high-dimensional miRNA profiling platform (2009) (26)
- The uptake of agalacto‐glucocerebrosidase by rat hepatocytes and kupffer cells (1978) (25)
- A transwell assay that excludes exosomes for assessment of tunneling nanotube-mediated intercellular communication (2017) (24)
- Modulation of amyloid-β peptide-induced toxicity through inhibition of JNK nuclear localization and caspase-2 activation. (2010) (24)
- Polysome trafficking of transcripts and microRNAs in regenerating liver after partial hepatectomy. (2009) (24)
- MicroRNAs in the Evaluation and Potential Treatment of Liver Diseases (2016) (24)
- Gene repair in the new age of gene therapy (2002) (24)
- Alpha1-antitrypsin deficiency with cirrhosis associated with the protease inhibitor phenotype SZ. (1978) (24)
- Synthesis and Evaluation of Water‐Soluble Prodrugs of Ursodeoxycholic Acid (UDCA), an Anti‐apoptotic Bile Acid (2013) (23)
- Merit of an Ursodeoxycholic Acid Clinical Trial in COVID-19 Patients (2020) (22)
- Metabolism of intact and desialylated alpha 1-antitrypsin. (1978) (22)
- The role of retinoblastoma protein in apoptosis (2004) (21)
- Sleeping Beauty transposition in the mouse genome is associated with changes in DNA methylation at the site of insertion. (2006) (21)
- Pancreatic Cancer: Modulation of KRAS, MicroRNAs, and Intercellular Communication in the Setting of Tumor Heterogeneity (2013) (21)
- ATP-dependent proton transport by isolated brain clathrin-coated vesicles. Role of clathrin and other determinants of acidification. (1985) (21)
- Plasma levels of ursodeoxycholic acid in black bears, Ursus americanus: seasonal changes. (2006) (21)
- Regulation of bile acid synthesis by deoxycholic acid in the rat: Different effects on cholesterol 7α‐hydroxylase and sterol 27‐hydroxylase (1995) (21)
- Role of nuclear steroid receptors in apoptosis. (2009) (20)
- Immune-Mediated Therapies for Liver Cancer (2017) (20)
- DNA methylation of Sleeping Beauty with transposition into the mouse genome (2005) (20)
- Tauroursodeoxycholic acid improves the survival and function of nigral transplants in a rat model of Parkinson's disease. (2002) (20)
- Hepatic membrane receptors for glycoproteins. (1986) (20)
- LXRα Promotes Hepatosteatosis in Part Through Activation of MicroRNA‐378 Transcription and Inhibition of Ppargc1β Expression (2019) (20)
- MicroRNA-206 promotes the recruitment of CD8+ T cells by driving M1 polarisation of Kupffer cells (2021) (19)
- Mitochondrial MicroRNAs and Their Potential Role in Cell Function (2014) (19)
- Regulation of bile acid synthesis by deoxycholic acid in the rat: Different effects on cholesterol 7α-hydroxylase and sterol 27-hydroxylase (1995) (19)
- High-level genomic integration, epigenetic changes, and expression of sleeping beauty transgene. (2010) (19)
- Prevention of Acute Kidney Injury by Tauroursodeoxycholic Acid in Rat and Cell Culture Models (2012) (18)
- Imprinting defects at human 14q32 locus alters gene expression and is associated with the pathobiology of osteosarcoma (2016) (18)
- Ligand-induced modulation of the hepatic receptor for asialoglycoproteins in the human hepatoblastoma cell line, Hep G2. (1987) (18)
- Host–MicroRNA–Microbiota Interactions in Colorectal Cancer (2019) (17)
- Amyloid-β peptide-induced secretion of endoplasmic reticulum chaperone glycoprotein GRP94. (2011) (17)
- Modulation of steady‐state messenger RNA levels in the regenerating rat liver with bile acid feeding (2001) (17)
- Infrared spectroscopic study of ethanol-induced changes in rat liver plasma membrane. (1989) (17)
- Functional size of the human asialoglycoprotein receptor as determined by radiation inactivation. (1984) (16)
- Special Issue: MicroRNA Regulation in Health and Disease (2019) (16)
- A new era of gene editing for the treatment of human diseases. (2019) (16)
- The application of DNA repair vectors to gene therapy. (2002) (16)
- Stem Cell Origins and Animal Models of Hepatocellular Carcinoma (2010) (16)
- β‐globin matrix attachment region improves stable genomic expression of the Sleeping beauty transposon (2011) (16)
- β-Globin Sleeping Beauty Transposon Reduces Red Blood Cell Sickling in a Patient-Derived CD34+-Based In Vitro Model (2013) (16)
- Binding and internalization of transforming growth factor‐β1 by human hepatoma cells: Evidence for receptor recycling (1991) (15)
- Isolated Kupffer cells, endothelial cells and hepatocytes as investigative tools for liver research. (1981) (15)
- CRISPR/Cas9-Based Lateral Flow and Fluorescence Diagnostics (2021) (15)
- MicroRNA-15a/16-1 Prevents Hepatocellular Carcinoma by Disrupting the Communication between Kupffer Cells and Tregs. (2021) (15)
- Changes in cell cycle‐associated gene expression in a model of impaired liver regeneration (1994) (15)
- Pharmacokinetics, Safety, and Tolerability of Orally Administered Ursodeoxycholic Acid in Patients With Parkinson's Disease—A Pilot Study (2020) (15)
- Erythroid-Specific Expression of β-globin from Sleeping Beauty-Transduced Human Hematopoietic Progenitor Cells (2011) (14)
- Lost in translation: applying 2D intercellular communication via tunneling nanotubes in cell culture to physiologically relevant 3D microenvironments (2017) (14)
- Activation of microRNA-378a-3p biogenesis promotes hepatic secretion of VLDL and hyperlipidemia by modulating ApoB100-Sortilin1 axis (2020) (14)
- Targeted gene correction strategies. (2001) (14)
- Gene editing technology as an approach to the treatment of liver diseases (2016) (14)
- Ursodeoxycholic acid: A promising therapeutic target for inflammatory bowel diseases? (2019) (14)
- Cell surface receptors in the liver. (1979) (13)
- The retinoblastoma gene product is a negative modulator of the apoptotic pathway. (1996) (13)
- Interspecies Organogenesis for Human Transplantation (2019) (13)
- Cell-mediated cytotoxicity of desialylated human lymphocytes induced by a mitogenic mammalian liver protein (1978) (13)
- Ursodeoxycholic acid modulates the ubiquitin-proteasome degradation pathway of p53. (2010) (13)
- Modification of hepatic genomic DNA using RNA/DNA oligonucleotides (2002) (13)
- Site-specific base changes in the coding or promoter region of the human β- and γ-globin genes by single-stranded oligonucleotides (2005) (12)
- Evidence For the Presence of the Asialoglycoprotein Receptor in Coated Vesicles Isolated from Rat Liver (2007) (12)
- Enhanced primer selection and synthetic amplicon templates optimize high-resolution melting analysis of single-nucleotide polymorphisms in a large population. (2013) (12)
- Short, single-stranded oligonucleotides mediate targeted nucleotide conversion using extracts from isolated liver mitochondria. (2003) (11)
- A differential scanning calorimetric study of brain clathrin. (1989) (11)
- Gene expression profiling of MYC-driven tumor signatures in porcine liver stem cells by transcriptome sequencing. (2015) (11)
- Binding of the SARS-CoV-2 Spike Protein to the Asialoglycoprotein Receptor on Human Primary Hepatocytes and Immortalized Hepatocyte-Like Cells by Confocal Analysis (2021) (10)
- Transcriptional rate and steady‐state changes of retinoblastoma mRNA in regenerating rat liver (1994) (10)
- Unbound E2F modulates TGF-β1-induced apoptosis in HuH-7 cells (2002) (10)
- Studies of complement receptors on cytotoxic effector cells in human peripheral blood. (1978) (10)
- Circulating microRNAs: novel biomarkers for early detection of colorectal cancer. (2015) (10)
- Advancing One Health Policy and Implementation Through the Concept of One Medicine One Science (2015) (9)
- Gene editing for inflammatory disorders (2018) (9)
- In Vivo Application of Non-viral Vectors to the Liver (2002) (9)
- Membrane lipid response to clathrin coat protein determined by infrared spectroscopy. Possible involvement in coated vesicle formation. (1984) (9)
- Systematic Review of Candidate Single-nucleotide Polymorphisms as Biomarkers for Responsiveness to Neoadjuvant Chemoradiation for Rectal Cancer. (2015) (9)
- The selective hepatic uptake of desialylated peripheral blood mononuclear cells in rabbits (1980) (8)
- Utility of Common Marmoset (Callithrix jacchus) Embryonic Stem Cells in Liver Disease Modeling, Tissue Engineering and Drug Metabolism (2020) (8)
- Oligonucleotide-mediated site-directed gene repair. (2002) (8)
- Functional and physical molecular size of the chicken hepatic lectin determined by radiation inactivation and sedimentation equilibrium analysis. (1990) (8)
- A new era of genetic engineering for autoimmune and inflammatory diseases. (2019) (8)
- CRISPR/Cas9 therapeutics for liver diseases (2018) (8)
- Identification of receptors for immunoglobulin and complement on mouse Kupffer cells in vitro (1978) (8)
- Liver development is restored by blastocyst complementation of HHEX knockout in mice and pigs (2021) (8)
- A Novel Link Between REC2, a DNA Recombinase, the Retinoblastoma Protein, and Apoptosis* (1997) (8)
- Fooling the Fas ligand in death (2006) (8)
- Site-specific base changes in the coding or promoter region of the human beta- and gamma-globin genes by single-stranded oligonucleotides. (2005) (7)
- Erratum: Tauroursodeoxycholic acid improves the survival and function of nigral transplants in a rat model of Parkinson's Disease (Cell Transplantation 11:3 (195-205)) (2002) (7)
- Blood outgrowth endothelial cells as a vehicle for transgene expression of hepatocyte-secreted proteins via Sleeping Beauty. (2007) (7)
- Corrigendum to “Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference” [Biochem. Biophys. Res. Commun. 329 (2005) 646–652] (2005) (7)
- Development of immortalized human hepatocyte-like hybrid cells by fusion of multi-lineage progenitor cells with primary hepatocytes (2020) (7)
- Studies of lysosomal function: I. Metabolism of some complex lipids by isolated hepatocytes and Kupffer cells. (1978) (7)
- Liver Regeneration in the Acute Liver Failure Patient. (2018) (6)
- Membrane contents of distinct subpopulations of coated vesicles determined by scanning transmission electron microscopy. (1988) (6)
- Quantitative Assessment of Occipital Metabolic and Energetic Changes in Parkinson’s Patients, Using In Vivo 31P MRS-Based Metabolic Imaging at 7T (2021) (6)
- Isolation of mitochondria from liver and extraction of total RNA and protein: analyses of microRNA and protein expressions. (2015) (6)
- Establishment and characterization of a unique 1 microm diameter liver-derived progenitor cell line. (2010) (6)
- The binding site of chicken hepatic lectin. (1983) (6)
- 5. THE ROLE OF BILE ACIDS IN THE MODULATION OF APOPTOSIS (2004) (6)
- Bile Acids as Modulators of Apoptosis (2008) (6)
- High-resolution melting analysis of single nucleotide polymorphisms. (2015) (6)
- Unbound E2F modulates TGF-beta1-induced apoptosis in HuH-7 cells. (2002) (5)
- Novel mechanisms of chemoresistance by Fusobacterium nucleatum involve not so novel pathways of microRNAs and autophagy (2018) (5)
- A common variant in MTHFR influences response to chemoradiotherapy and recurrence of rectal cancer. (2015) (5)
- “Let my liver rather heat with wine” - a review of hepatic fibrosis pathophysiology and emerging therapeutics (2019) (4)
- Disease Genes and Gene Regulation by microRNAs (2010) (4)
- Quantitative real-time polymerase chain reaction (qRT-PCR) restriction fragment length polymorphism (RFLP) method for monitoring highly conserved transgene expression during gene therapy. (2008) (4)
- Hepatic Differentiation of Marmoset Embryonic Stem Cells and Functional Characterization of ESC-Derived Hepatocyte-Like Cells (2020) (4)
- Strategies for Hepatic Gene Correction (2002) (4)
- Human DNA Methyltransferase 3a does not Associate with MicroRNAs in the Regulation of DNA Methylation (2010) (4)
- 23 Targeted Gene Repair in Mammalian Cells Using Chimeric RNA/DNA Oligonucleotides (1999) (4)
- MicroRNA‐206 enhances antitumor immunity by disrupting the communication between malignant hepatocytes and regulatory T cells in c‐Myc mice (2021) (3)
- Gene therapy and CVD: how near are we? (2004) (3)
- In vitro Differentiation of Human TERT-Transfected Multi-Lineage Progenitor Cells (MLPC) into Immortalized Hepatocyte-Like Cells (2020) (3)
- Efficient silencing of hepatitis B virus S gene through CRISPR‐mediated base editing (2022) (3)
- Cyclins and gap junctions in liver growth and repair (1998) (2)
- Hemopexin Gene Therapy Inhibits Inflammation and Vaso-Occlusion in Transgenic Sickle Cell Mice (2015) (2)
- One Medicine One Science and policy. (2015) (2)
- No evidence of direct binding between ursodeoxycholic acid and the p53 DNA-binding domain. (2010) (2)
- Reversing Age-Related DNA Damage Through Engineered DNA Repair (2010) (2)
- Liver targeted gene therapy: Insights into emerging therapies. (2019) (2)
- The Evolution of Gene Therapy in the Treatment of Metabolic Liver Diseases (2020) (2)
- Author Correction: A guiding map for inflammation (2020) (2)
- Detection of Sleeping Beauty transposition in the genome of host cells by non-radioactive Southern blot analysis. (2016) (2)
- Cell-mediated cytotoxicity of desialylated human lymphocytes induced by a mitogenic mammalian liver protein. (1978) (2)
- Tauroursodeoxycholic acid prevents apoptosis induced by the neurotoxin 3-nitropropionic acid in rat neuronal cells: Evidence for a mitochondrial-dependent pathway that does not involve the permeability transition (2000) (2)
- 1081. Targeted Nanocapsules for Liver Cell-Type Delivery of Plasmids In Vivo (2006) (2)
- MicroRNA-378a-3p prevents initiation and growth of colorectal cancer by fine tuning polyamine synthesis (2022) (1)
- Use of vibrational spectroscopy in defining the role of clathrin in coated vesicle formation. (1986) (1)
- H-Ferritin Ferroxidase Activity Induces Cytoprotective Pathways and Inhibits Microvascular Stasis in Transgenic Sickle Mice (2012) (1)
- Erythroid-specific Expression of β-globin by Sleeping Beauty Transposon for Sickle Cell Disease (2014) (1)
- Function of nuclear steroid receptors in apoptosis: role of ursodeoxycholic acid (2007) (1)
- Animal Models of Liver Cancer (2014) (1)
- The Bioengineering of Exogenic Organs and/or Cells for Use in Regenerative Medicine (2019) (1)
- W1862 Proteoliposomes Containing Sendai Virus F-Glycoprotein for Hepatocyte-Targeted Gene Therapy of the Gunn Rat Model of Crigler-Najjar Syndrome Type 1 (2008) (1)
- Cellular and molecular mechanisms of hepatocellular carcinoma: an update (2012) (1)
- Isolation of Mitochondria from Liver and Extraction of Total RNA and Protein: Analyses of miRNA and Protein Expression. (2021) (1)
- Binding Studies of Bile Acids using the Native Fluorescence of the Tryptophan Residue Of Bax Protein (2006) (1)
- microRNA Regulation in Health and Disease (2020) (1)
- Hepatocellular Carcinoma (2014) (1)
- 985. Transposition of the Agouti Transgene by Sleeping Beauty Transposon Is Not Associated with Significant Changes in DNA Methylation in the Mouse Genome (2004) (0)
- Understanding brain microRNA profiling in the double transgenic APP/PS1 mouse model of Alzheimer's disease (2012) (0)
- Differentiation of Highly Conserved Host and Transgene mRNA in HO-1 Gene Therapy. (2007) (0)
- HMER_A_243277 15..27 (2020) (0)
- The selective hepatic uptake of desialylated peripheral blood mononuclear cells in rabbits. (1980) (0)
- Liver Regeneration in Acute and Acute-on-Chronic Liver Failure (2020) (0)
- Abstract 2037: Spatial omic changes of malignant pleural mesothelioma following treatment using tumor-treating fields (2022) (0)
- Tauroursodeoxycholic acid reduces apoptosis following myocardial infarction in the rat (2006) (0)
- 216. Gene Therapy of Huntington Disease Using RNA Interference and Sleeping Beauty Transposon (2004) (0)
- 184 Ursodeoxycholic acid prevents TGF-β1-induced apoptosis through modulation of the glucocorticoid receptor in primary rat hepatocytes (2003) (0)
- The mechanism of selective hepatic uptake of desialylated lymphocytes in the rabbit (1978) (0)
- Subconjunctival Delivery of a Neuroprotectant using Fibrin Sealant (2011) (0)
- Differential uptake of native and desialylated glucocere-brosidase by rat hepatocytes and Kupffer cells (1978) (0)
- HMER_A_213397 109..129 (2019) (0)
- Interspecies Chimeric Barriers for Generating Exogenic Organs and Cells for Transplantation (2022) (0)
- Genomic Structure and Function of the UDP-Glucuronosyltransferases (2002) (0)
- Efficient recovery of proteins from multiple source samples after trizol® or trizol®LS RNA extraction and long-term storage (2013) (0)
- Abstract 4368: MicroRNAs miR-503 and -182 regulate FBXW7 contributing to the malignant transformation to colon adenocarcinoma (2014) (0)
- Long-term gene expression mediated by the "sleeping beauty" DNA transposon system. (2002) (0)
- Pathophysiology of HCC (2014) (0)
- Heme Oxygenase-1 Gene Therapy in a Murine Model of Sickle Cell Disease. (2009) (0)
- Control of apoptosis in experimental alzheimer’s disease: Therapeutic opportunities for an ancient bile acid (2010) (0)
- 884 Ursodeoxycholic acid modulates the RB/E2F-1 apoptotic pathway in rat hepatocytes as determined by microarray analysis (2003) (0)
- Differentiation of immortalized human MLPC to alveolar type 2 (AT2)-like cells: ACE-2 expression and binding of SARS-CoV-2 spike and spike 1 proteins (2021) (0)
- Precision medicine, agriculture, and genome editing: science and ethics (2019) (0)
- Nuclear steroid receptors in apoptosis (2010) (0)
- In Silico Stage-Matching of Human, Marmoset, Mouse, and Pig Embryos to Enhance Organ Development Through Interspecies Chimerism (2023) (0)
- Sleeping beauty transposon mediates long-term expression of GFP and UDP-glucuronosyltransferase in liver (2001) (0)
- Chemotherapy-Induced Tunneling Nanotubes Mediate Intercellular Drug Efflux in Pancreatic Cancer (2018) (0)
- Treatment with Tumor-Treating Fields (TTFields) Suppresses Intercellular Tunneling Nanotube Formation In Vitro and Upregulates Immuno-Oncologic Biomarkers In Vivo in Malignant Mesothelioma (2022) (0)
- Induction of Endogenous Repair Mechanisms by Single-Stranded DNA Oligonucleotide Therapy for Correction of the DNA-PK Mutation in Murine Severe Combined Immune Deficiency. (2006) (0)
- Novel Therapeutic Strategies to Combat HCC (2014) (0)
- A transwell assay that excludes exosomes for assessment of tunneling nanotube-mediated intercellular communication (2017) (0)
- 154. Small inhibitory RNA expressed from sleeping beauty transposons can reduce alpha1-antitrypsin expression (2004) (0)
- Abstract 3599: Long-distance intercellular transport of microRNAs via tunneling nanotubes: Role in tumor-stroma interactions and malignant potential (2014) (0)
- Molecular Mechanisms of HCC (2014) (0)
- Abstract 3189: Tunneling nanotube formation is significantly upregulated in invasive cancer cells (2015) (0)
- Novel mechanisms of chemoresistance in ovarian cancer: The role of tunneling nanotubes (2014) (0)
- Differential expression of Bcl-2 gene family induced by transforming growth factor beta1 (TGF-beta1) is regulated by ursodeoxycholate (UDC) (2002) (0)
- Liver Regeneration in Acute on Chronic Liver Failure (2023) (0)
- Current Diagnosis and Treatment Options for HCC (2014) (0)
- A Positive Feedback Loop between Cholesterol Synthesis and the Pentose Phosphate Pathway Drives HCC in c-Myc Mice (2022) (0)
- A qRT-PCR RFLP Method for Monitoring Highly Conserved Transgene Expression during Gene Therapy (2009) (0)
- HMER_A_301979 37..44 (2021) (0)
- Cellular Biology of the Normal Liver (2006) (0)
- The Dynamics of Clathrin and the Coated Vesicle Pathway (1986) (0)
- P53 is a specific molecular target of ursodeoxycholic acid in regulating apoptosis (2007) (0)
- Protection against Acute Kidney Injury by TUDCA Protection against Acute Kidney Injury by TUDCA (2007) (0)
- Hepatic Metabolism of Serum Asialoglycoproteins (1982) (0)
- Selective hepatic uptakeofhumanf3-hexosaminidas (1979) (0)
- Word count : 6094 Number of figures and tables : 6 figures Conflicts of Interest (2018) (0)
- Correction: β-Globin Sleeping Beauty Transposon Reduces Red Blood Cell Sickling in a Patient-Derived CD34+-Based In Vitro Model (2014) (0)
- Game and players (2007) (0)
- Increased liver tissue ursodeoxycholic acid (UDCA) concentration and reduced lithocholate formation in rats orally administered the taurine conjugate of UDCA compared with uncojugated UDCA (1995) (0)
- 428 Development of an Oncolytic Adenovirus to Treat Metastatic Colorectal Cancer (2023) (0)
- Differentiation of immortalized human multi-lineage progenitor to alveolar type 2-like cells: angiotensin-converting enzyme 2 expression and binding of severe acute respiratory syndrome coronavirus 2 spike and spike 1 proteins (2021) (0)
- Abstract 4042: Loss of imprinting at the 14q32 locus contributes to osteosarcoma (2012) (0)
- 178. Site-Specific Base Alteration in the Promoter Region of the Human Gamma Globin Gene by Single-Stranded Oligonucleotides for Gene Therapy of Sickle Cell Disease (2004) (0)
- A method for lifelong genetic manipulation of regenerating hepatocytes in mouse (2008) (0)
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