Clotilde Théry
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French molecular biologist and researcher
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Clotilde Thérybiology Degrees
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Cell Biology
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Biology
Clotilde Théry's Degrees
- PhD Molecular Biology Université Paris Cité
- Masters Biochemistry Université Paris Cité
- Bachelors Biology Université Paris Cité
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Why Is Clotilde Théry Influential?
(Suggest an Edit or Addition)According to Wikipedia, Clotilde Théry is a professor and INSERM director of research at Institut Curie in Paris, France. She is president of the International Society for Extracellular Vesicles , where she previously served as founding secretary general and as editor-in-chief of the Journal of Extracellular Vesicles. She is team leader of the group "Extracellular Vesicles, Immune Responses and Cancer" within the INSERM Unit 932 on "Immunity and Cancer." Théry researches extracellular vesicles that are released by immune and tumor cellss, including exosomess that originate in the multivesicular body.
Clotilde Théry's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines (2018) (5288)
- Exosomes: composition, biogenesis and function (2002) (4283)
- Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids (2006) (4266)
- Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. (2014) (4055)
- Membrane vesicles as conveyors of immune responses (2009) (3446)
- Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes (2016) (2221)
- Communication by Extracellular Vesicles: Where We Are and Where We Need to Go (2016) (2167)
- Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles (2014) (1971)
- Antigen presentation and T cell stimulation by dendritic cells. (2002) (1939)
- Rab27a and Rab27b control different steps of the exosome secretion pathway (2010) (1917)
- Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication (2019) (1809)
- Standardization of sample collection, isolation and analysis methods in extracellular vesicle research (2013) (1798)
- Proteomic Analysis of Dendritic Cell-Derived Exosomes: A Secreted Subcellular Compartment Distinct from Apoptotic Vesicles1 (2001) (1439)
- Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming (2001) (1422)
- Biogenesis and secretion of exosomes. (2014) (1260)
- Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation (2012) (1104)
- Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles (2013) (1062)
- Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. (1999) (1025)
- Fcγ Receptor–mediated Induction of Dendritic Cell Maturation and Major Histocompatibility Complex Class I–restricted Antigen Presentation after Immune Complex Internalization (1999) (990)
- Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses (2011) (932)
- Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper (2015) (922)
- Indirect activation of naïve CD4+ T cells by dendritic cell–derived exosomes (2002) (847)
- Exosomes: secreted vesicles and intercellular communications (2011) (807)
- EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research (2017) (699)
- Techniques used for the isolation and characterization of extracellular vesicles: results of a worldwide survey (2016) (596)
- ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. (2005) (538)
- Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper (2017) (499)
- Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation (2012) (483)
- Rab27a supports exosome-dependent and -independent mechanisms that modify the tumor microenvironment and can promote tumor progression. (2012) (477)
- Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC (2015) (473)
- Exosomes: immune properties and potential clinical implementations (2011) (471)
- 1 Rab 27 a and Rab 27 b control different steps of the exosome secretion pathway (2009) (391)
- The cell biology of antigen presentation in dendritic cells. (2001) (347)
- Extracellular vesicles or exosomes? On primacy, precision, and popularity influencing a choice of nomenclature (2019) (293)
- Lactadherin promotes VEGF-dependent neovascularization (2005) (292)
- Bacteria-induced neo-biosynthesis, stabilization, and surface expression of functional class I molecules in mouse dendritic cells. (1998) (286)
- Dendritic cell-derived exosomes for cancer immunotherapy: what's next? (2010) (286)
- Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses. (2005) (277)
- A novel community driven software for functional enrichment analysis of extracellular vesicles data (2017) (272)
- Targeting tumor antigens to secreted membrane vesicles in vivo induces efficient antitumor immune responses. (2008) (264)
- Phagocytosis executes delayed neuronal death after focal brain ischemia (2013) (254)
- CD8+ Dendritic Cells Use LFA-1 to Capture MHC-Peptide Complexes from Exosomes In Vivo1 (2007) (246)
- Why the need and how to approach the functional diversity of extracellular vesicles (2017) (230)
- Transmission of innate immune signaling by packaging of cGAMP in viral particles (2015) (219)
- TSAP6 Facilitates the Secretion of Translationally Controlled Tumor Protein/Histamine-releasing Factor via a Nonclassical Pathway* (2004) (209)
- Qualitative differences in T‐cell activation by dendritic cell‐derived extracellular vesicle subtypes (2017) (208)
- Cytotoxic Effect of Brain Macrophages on Developing Neurons (1991) (195)
- Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 (2021) (182)
- Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility (2017) (175)
- Prospects for exosomes in immunotherapy of cancer (2006) (172)
- MFG-E8 Mediates Primary Phagocytosis of Viable Neurons during Neuroinflammation (2012) (167)
- Exosomes from Bronchoalveolar Fluid of Tolerized Mice Prevent Allergic Reaction1 (2008) (166)
- Updated Technology to Produce Highly Immunogenic Dendritic Cell-derived Exosomes of Clinical Grade: A Critical Role of Interferon-&ggr; (2011) (163)
- Methods for Separation and Characterization of Extracellular Vesicles: Results of a Worldwide Survey Performed by the ISEV Rigor and Standardization Subcommittee (2020) (144)
- A role for HLA‐DO as a co‐chaperone of HLA‐DM in peptide loading of MHC class II molecules (1998) (143)
- Dendritic cell derived‐exosomes: biology and clinical implementations (2006) (140)
- Accumulation of MFG-E8/lactadherin on exosomes from immature dendritic cells. (2005) (122)
- Cancer: Diagnosis by extracellular vesicles (2015) (112)
- Exosomes and communication between tumours and the immune system: are all exosomes equal? (2013) (108)
- A role for HGF/SF in neural induction and its expression in Hensen's node during gastrulation. (1995) (105)
- SnapShot: Extracellular Vesicles (2020) (98)
- Expression of macrophage colony‐stimulating factor gene in the mouse brain during development (1990) (94)
- Expression of HGF/SF, HGF1/MSP, and c-met suggests new functions during early chick development. (1995) (89)
- The power of imaging to understand extracellular vesicle biology in vivo (2021) (88)
- CD8+ tumor-infiltrating T cells are trapped in the tumor-dendritic cell network. (2013) (80)
- Extracellular vesicles containing ACE2 efficiently prevent infection by SARS‐CoV‐2 Spike protein‐containing virus (2020) (79)
- International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 (2020) (76)
- Downregulation of in vitro neurotoxicity of brain macrophages by prostaglandin E2 and a β‐adrenergic agonist (1994) (71)
- Molecular Characterization of Dendritic Cell-Derived Exosomes (1999) (65)
- Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles (2021) (64)
- A brief history of nearly EV‐erything – The rise and rise of extracellular vesicles (2021) (63)
- Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells (2021) (63)
- Interleukin 1 and Tumor Necrosis Factor‐α Stimulate the Production of Colony‐Stimulating Factor 1 by Murine Astrocytes (1992) (61)
- The Cell Biology of Neurogenesis : Toward an Understanding of the Development and Evolution of the Neocortex (2014) (57)
- Milk fat globule—epidermal growth factor—factor VIII (MFGE8)/lactadherin promotes bladder tumor development (2011) (48)
- An essential role for decorin in bladder cancer invasiveness (2013) (46)
- ISEV2018 abstract book (2018) (46)
- Antigen Localization Controls T Cell-Mediated Tumor Immunity (2011) (46)
- Secretory granules of mast cells accumulate mature and immature MHC class II molecules. (2001) (43)
- New Blocking Antibodies Impede Adhesion, Migration and Survival of Ovarian Cancer Cells, Highlighting MFGE8 as a Potential Therapeutic Target of Human Ovarian Carcinoma (2013) (41)
- General Strategy for Decoration of Enveloped Viruses with Functionally Active Lipid-Modified Cytokines (2007) (41)
- Different immunogenicity but similar antitumor efficacy of two DNA vaccines coding for an antigen secreted in different membrane vesicle-associated forms (2014) (40)
- Unraveling the physiological functions of exosome secretion by tumors (2013) (40)
- Influence of interleukin-1 and tumor necrosis factor alpha on the growth of microglial cells in primary cultures of mouse cerebral cortex: involvement of colony-stimulating factor 1 (1993) (40)
- Extracellular vesicles and chronic inflammation during HIV infection (2019) (37)
- MHC Class II Transport from Lysosomal Compartments to the Cell Surface Is Determined by Stable Peptide Binding, But Not by the Cytosolic Domains of the α- and β-Chains (1998) (35)
- Acetylcholinesterase is not a generic marker of extracellular vesicles (2019) (32)
- Roles of kringle domain-containing serine proteases in epithelial-mesenchymal transitions during embryonic development. (1996) (27)
- Rigor and standardization of extracellular vesicle research: Paving the road towards robustness (2020) (26)
- Neurotoxicity of brain macrophages. (1993) (23)
- Comparative analysis of the tissue distribution of three fibroblast growth factor receptor mRNAs during amphibian morphogenesis. (1994) (22)
- Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus (2020) (22)
- No Significant CTL Cross-Priming by Dendritic Cell-Derived Exosomes during Murine Lymphocytic Choriomeningitis Virus Infection1 (2009) (21)
- Maternal environment interacts with modifier genes to influence progression of nephrotic syndrome. (2008) (21)
- The launch of Journal of Extracellular Vesicles (JEV), the official journal of the International Society for Extracellular Vesicles – about microvesicles, exosomes, ectosomes and other extracellular vesicles (2012) (20)
- Unbiased proteomic profiling of host cell extracellular vesicle composition and dynamics upon HIV‐1 infection (2021) (20)
- The International Society for Extracellular Vesicles launches the first massive open online course on extracellular vesicles (2016) (18)
- ISEV and ISCT statement on EVs from MSCs and other cells: considerations for potential therapeutic agents to suppress COVID-19 (2020) (17)
- Journal of extracellular vesicles: the seven year itch! (2019) (16)
- Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcome (2022) (16)
- Of mice and frogs. (1994) (15)
- Extending gene ontology in the context of extracellular RNA and vesicle communication (2016) (15)
- CHAPTER 13 – Dendritic cell-derived exosomes (2001) (15)
- Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking and synchronized extracellular vesicle release of CD9 and CD63 (2020) (14)
- MHC class II transport from lysosomal compartments to the cell surface is determined by stable peptide binding, but not by the cytosolic domains of the alpha- and beta-chains. (1998) (13)
- European Network on Microvesicles and Exosomes in Health and Disease (ME-HaD). (2017) (9)
- Involvement of Livertine, a hepatocyte growth factor family member, in neural morphogenesis (1996) (8)
- Vivo MHC-Peptide Complexes from Exosomes In Dendritic Cells Use LFA-1 to Capture + CD 8 Amigorena and Clotilde Théry (2007) (8)
- Urinary extracellular vesicles contain mature transcriptome enriched in circular and long noncoding RNAs with functional significance in prostate cancer (2022) (7)
- MFGE8 does not orchestrate clearance of apoptotic neurons in a mouse model of Parkinson's disease (2013) (7)
- Faculty Opinions recommendation of Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. (2011) (6)
- Vesicles Compartment Distinct from Apoptotic Exosomes : A Secreted Subcellular Proteomic Analysis of Dendritic Cell-Derived (2001) (6)
- ISEV RNA Workshop—New York City, October 1–2, 2012 (2012) (4)
- Extracellular vesicles: eat glutamine and spit acidic bubbles (2020) (3)
- naive T cell priming ICAM-1 on exosomes from mature dendritic cells is critical for efficient (2013) (3)
- Exosomes: Naturally Occurring Minimal Antigen-Presenting Units (2010) (3)
- MPAPASS software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays (2022) (3)
- Homosalate boosts the release of tumour‐derived extracellular vesicles with protection against anchorage‐loss property (2022) (2)
- Evidence for a novel growth factor in Xenopus oocytes. (1989) (2)
- Exosomes from bronchoalveolar fluid of tolerized mice prevent allergen-specific allergic reaction (2007) (2)
- MFGE8 Does Not Influence Chorio-Retinal Homeostasis or Choroidal Neovascularization in vivo (2012) (2)
- Scientific Program 2012 ISEV meeting Wednesday 18th April (2012) (2)
- Cigarette smoke-induced extracellular vesicles from dendritic cells alter T-cell activation and HIV replication. (2022) (2)
- Homosalate boosts the release of tumor-derived Extracellular Vesicles with anti-anoikis properties (2021) (1)
- [Extracellular vesicles: How to pass in a few decades from a status of cellular debris, or worse, garbage bags, to that of inter-cellular messengers]. (2021) (1)
- [In vivo secreted vesicles allow improvement of anti-tumor immune response]. (2008) (1)
- Fibroblast growth factor-2 bound to specific dermal fibroblast-derived extracellular vesicles is protected from degradation (2022) (0)
- B39 Modelling and biological evidence for alteration of extracellular vesicles in huntington’s disease (2016) (0)
- [Lactadherin promotes VEGF-dependent neovascularization]. (2005) (0)
- MPA PASS Enables Stitched Multiplex Multi-Dimensional EV Repertoire Analysis (2021) (0)
- Faculty Opinions recommendation of GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c(+)MHCII(+) Macrophages and Dendritic Cells. (2015) (0)
- Faculty Opinions recommendation of Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C. (2011) (0)
- Obituary (2014) (0)
- Infection Murine Lymphocytic Choriomeningitis Virus Dendritic Cell-Derived Exosomes during No Significant CTL Cross-Priming by Amigorena and (2009) (0)
- Faculty Opinions recommendation of Unstressing intemperate models: how cold stress undermines mouse modeling. (2012) (0)
- Towards a molecular understanding of neural induction (1995) (0)
- Comparative analysis of the tissue distribution of the three fibroblast growth facteur receptor mRNA during amphibien morphogenesis (1995) (0)
- Faculty Opinions recommendation of Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes. (2011) (0)
- Urinary Extracellular Vesicles contain simplified transcriptomes enriched in circular & long noncoding RNAs with functional significance in prostate cancer (2021) (0)
- Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication (2019) (0)
- Faculty Opinions recommendation of [CONFERENCE POSTER]: Microvesicles of Dictyostelium as a model of eukaryotic extracellular vesicles. (2012) (0)
- Detection of tumor-derived extracellular vesicles interactions with immune cells is dependent on EV-labelling methods (2023) (0)
- D18 Small extracellular vesicles in response to mutant huntingtin (2022) (0)
- Applying extracellular vesicles based therapeutics in clinical trials (cid:2) an ISEV position paper (2015) (0)
- Cellule de suppression des anticorps liée à la lactadhérine (2013) (0)
- Faculty Opinions recommendation of Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs. (2014) (0)
- Proteomic Profiling Allows Unbiased Compositional Analysis of Extracellular Vesicle Subtypes (2020) (0)
- Cell-Mediated Tumor Immunity Antigen Localization Controls T (2011) (0)
- Milk Fat Globule-epidermal Growth Factor-factor VIII (MFGE8) / Lactadherin Deficiency Does Not Alter Retinal Homeostasis And Choroidal Neovascularization (2011) (0)
- Obituary: Dr Melissa Piper (2014) (0)
- Extracellular vesicles and co-isolated endogenous retroviruses differently affect dendritic cells (2023) (0)
- Faculty Opinions recommendation of Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation. (2014) (0)
- Prostate cancer urinary Extracellular Vesicles are enriched in cytoplasmic intron-free mRNAs and circular/long noncoding RNAs with functional significance (2021) (0)
- CD 8 + Tumor-Infiltrating T Cells Are Trapped in the Tumor-Dendritic Cell Network 1 (2013) (0)
- Faculty Opinions recommendation of B lymphocytes secrete antigen-presenting vesicles. (2011) (0)
- Circulating extracellular vesicles provide valuable protein, but not DNA, biomarkers in metastatic breast cancer (2022) (0)
- Lactadherin‐Dependent Phagocytosis and Clearance of Oxidized Erythrocytes Following Intra‐Plaque Hemorrhage (2007) (0)
- Abstract B175: Lactadherin/MFGE8 favors bladder tumor progression by promoting tolerogenic immune responses (2009) (0)
- Faculty Opinions recommendation of MicroRNAs are exported from malignant cells in customized particles. (2012) (0)
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