Connie Eaves

Q: What Schools Are Affiliated With Connie Eaves

Connie Eaves is affiliated with the following schools: Catholic University of Korea, University of Hong Kong, University of British Columbia, Queen's University at Kingston, University of Toronto, University of Manchester

Connie Eaves's AcademicInfluence.com Rankings

Connie Eaves

Law

#1692

World Rank

#2117

Historical Rank

Common Law

#43

World Rank

#48

Historical Rank

law Degrees

Download Badge

Connie Eaves's Degrees

PhD Medical Genetics University of British Columbia
Doctorate Medicine University of British Columbia

Why Is Connie Eaves Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Connie Jean Eaves, CorrFRSE , is a Canadian biologist with significant contributions to cancer and stem cell research. Eaves is a professor generics of genetics at the University of British Columbia and is also the co-founder with Allen C Eaves of Terry Fox Laboratory .

(See a Problem?)

Connie Eaves's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. (2006) (2967)
The clonal and mutational evolution spectrum of primary triple-negative breast cancers (2012) (1807)
Purification and unique properties of mammary epithelial stem cells (2006) (1593)
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (2008) (1105)
Cancer stem cells: an evolving concept (2012) (1093)
Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro. (1989) (750)
Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers. (1990) (713)
Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. (1995) (648)
Cancer stem cell definitions and terminology: the devil is in the details (2012) (619)
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. (1994) (587)
Long-term propagation of distinct hematopoietic differentiation programs in vivo. (2007) (586)
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution (2014) (566)
Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia. (1999) (553)
Correction of Sickle Cell Disease in Transgenic Mouse Models by Gene Therapy (2001) (533)
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia. (2011) (514)
Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines. (1983) (502)
Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scid/scid mice. (1997) (502)
Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy. (1990) (477)
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin (2007) (455)
Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal (2014) (387)
Hematopoietic stem cells: concepts, definitions, and the new reality. (2015) (384)
Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies (2007) (373)
Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium. (1996) (373)
Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue (2001) (365)
Differential cytokine effects on primitive (CD34+CD38-) human hematopoietic cells: novel responses to Flt3-ligand and thrombopoietin (1996) (364)
The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (2016) (360)
Long-term marrow culture reveals chromosomally normal hematopoietic progenitor cells in patients with Philadelphia chromosome-positive chronic myelogenous leukemia. (1983) (346)
Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect. (2006) (338)
Transcriptome analysis of the normal human mammary cell commitment and differentiation process. (2008) (330)
Enzymatic treatment of long-term human marrow cultures reveals the preferential location of primitive hemopoietic progenitors in the adherent layer. (1983) (326)
A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability (2008) (324)
Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential. (2009) (313)
Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer. (1991) (308)
Steroid hormone receptor status of mouse mammary stem cells. (2006) (304)
High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays (2011) (303)
Cytokine manipulation of primitive human hematopoietic cell self-renewal. (1997) (303)
Expansion in vitro of adult murine hematopoietic stem cells with transplantable lympho-myeloid reconstituting ability. (1997) (299)
The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells (2013) (297)
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy (2017) (293)
Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G(2)/M transit and do not reenter G(0). (2000) (284)
Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells. (1991) (284)
Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs. (2012) (278)
Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals. (2016) (277)
Selective expression of CD45 isoforms on functional subpopulations of CD34+ hemopoietic cells from human bone marrow (1990) (270)
Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia. (1999) (267)
Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation. (2012) (262)
Functional differences between transplantable human hematopoietic stem cells from fetal liver, cord blood, and adult marrow. (1999) (258)
Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast. (1998) (256)
Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties (2007) (251)
Enhanced detection, maintenance, and differentiation of primitive human hematopoietic cells in cultures containing murine fibroblasts engineered to produce human steel factor, interleukin-3, and granulocyte colony-stimulating factor. (1996) (251)
Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice. (1997) (249)
Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. I. Stimulatory role of a variety of mesenchymal cell activators and inhibitory role of TGF-beta. (1990) (247)
The repopulation potential of fetal liver hematopoietic stem cells in mice exceeds that of their liver adult bone marrow counterparts. (1996) (239)
Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia. (2015) (233)
The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets. (2006) (226)
Human granulocyte-macrophage colony-stimulating factor is a growth factor active on a variety of cell types of nonhemopoietic origin. (1988) (224)
Unregulated proliferation of primitive chronic myeloid leukemia progenitors in the presence of normal marrow adherent cells. (1986) (213)
Prognostic implications of differences in telomere length between normal and malignant cells from patients with chronic myeloid leukemia measured by flow cytometry. (2000) (212)
Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-beta2 microglobulin-null mice. (2001) (211)
Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis. (1996) (202)
High level engraftment of NOD/SCID mice by primitive normal and leukemic hematopoietic cells from patients with chronic myeloid leukemia in chronic phase. (1998) (200)
Erythropoietin (Ep) dose-response curves for three classes of erythroid progenitors in normal human marrow and in patients with polycythemia vera (1978) (192)
Permanent and panerythroid correction of murine β thalassemia by multiple lentiviral integration in hematopoietic stem cells (2002) (186)
Primitive quiescent leukemic cells from patients with chronic myeloid leukemia spontaneously initiate factor-independent growth in vitro in association with up-regulation of expression of interleukin-3. (2001) (183)
Rapid decline of chronic myeloid leukemic cells in long-term culture due to a defect at the leukemic stem cell level. (1992) (181)
Characterization of primitive hematopoietic cells in normal human peripheral blood. (1992) (179)
Regulation of Hematopoietic Stem Cells by the Steel Factor/KIT Signaling Pathway (2008) (179)
Properties of the earliest clonogenic hemopoietic precursors to appear in the developing murine yolk sac. (1986) (177)
Evidence of both ontogeny and transplant dose-regulated expansion of hematopoietic stem cells in vivo. (1996) (175)
Alkaline Phosphatase‐Positive Colony Formation Is a Sensitive, Specific, and Quantitative Indicator of Undifferentiated Human Embryonic Stem Cells (2008) (174)
Epithelial Progenitors in the Normal Human Mammary Gland (2005) (172)
Comprehensive microRNA expression profiling of the hematopoietic hierarchy (2010) (171)
Autografting with cultured marrow in chronic myeloid leukemia: results of a pilot study. (1994) (170)
Hematopoietic stem cell heterogeneity takes center stage. (2012) (168)
Mutagenesis of retroviral vectors transducing human beta‐globin gene and beta‐globin locus control region derivatives results in stable transmission of an active transcriptional structure. (1994) (161)
Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance. (2010) (160)
Self-renewal of hemopoietic stem cells during mixed colony formation in vitro. (1981) (160)
Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells. (2002) (155)
Efficient retroviral-mediated gene transfer to human cord blood stem cells with in vivo repopulating potential. (1998) (154)
Instability of BCR-ABL gene in primary and cultured chronic myeloid leukemia stem cells. (2007) (153)
Successful autografting in chronic myeloid leukaemia after maintenance of marrow in culture. (1989) (152)
Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors. (2012) (148)
ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signaling (2014) (147)
Direct evidence for multiple self-renewal divisions of human in vivo repopulating hematopoietic cells in short-term culture. (1999) (146)
Proliferation of totipotent hematopoietic stem cells in vitro with retention of long-term competitive in vivo reconstituting ability. (1992) (144)
Regulated proliferation of primitive hematopoietic progenitor cells in long-term human marrow cultures. (1985) (144)
Distinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells. (2001) (143)
Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice. (2002) (141)
Elucidating critical mechanisms of deregulated stem cell turnover in the chronic phase of chronic myeloid leukemia (2002) (141)
Expansion of Hematopoietic Progenitor Cell Populations in Stirred Suspension Bioreactors of Normal Human Bone Marrow Cells (1994) (138)
A comparison of long-term repopulating hematopoietic stem cells in fetal liver and adult bone marrow from the mouse. (1996) (138)
Transplantable hematopoietic stem cells in human fetal liver have a CD34(+) side population (SP)phenotype. (2001) (137)
Different subsets of primary chronic myeloid leukemia stem cells engraft immunodeficient mice and produce a model of the human disease (2005) (136)
NOD/SCID mice engineered to express human IL-3, GM-CSF and Steel factor constitutively mobilize engrafted human progenitors and compromise human stem cell regeneration (2004) (135)
ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium (2011) (132)
Unresponsiveness of primitive chronic myeloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cells. (1993) (131)
Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo. (2001) (130)
High-resolution video monitoring of hematopoietic stem cells cultured in single-cell arrays identifies new features of self-renewal. (2006) (127)
Insights into the stem cells of chronic myeloid leukemia (2010) (127)
Characterization of primitive subpopulations of normal and leukemic cells present in the blood of patients with newly diagnosed as well as established chronic myeloid leukemia. (1996) (124)
Improved engraftment of human acute myeloid leukemia progenitor cells in beta 2-microglobulin-deficient NOD/SCID mice and in NOD/SCID mice transgenic for human growth factors (2003) (124)
Amplification of Sca-1+ Lin- WGA+ cells in serum-free cultures containing steel factor, interleukin-6, and erythropoietin with maintenance of cells with long-term in vivo reconstituting potential. (1994) (124)
Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors. (2013) (122)
Sustained proliferation, multi‐lineage differentiation and maintenance of primitive human haemopoietic cells in NOD/SCID mice transplanted with human cord blood (1997) (121)
Characterization and purification of a primitive hematopoietic cell type in adult mouse marrow capable of lymphomyeloid differentiation in long-term marrow "switch" cultures. (1995) (120)
A ligand-receptor signaling threshold model of stem cell differentiation control: a biologically conserved mechanism applicable to hematopoiesis. (2000) (118)
Kinetics of committed and primitive blood progenitor mobilization after chemotherapy and growth factor treatment and their use in autotransplants. (1994) (117)
Different in vivo repopulating activities of purified hematopoietic stem cells before and after being stimulated to divide in vitro with the same kinetics. (2003) (114)
Targeting YB-1 in HER-2 overexpressing breast cancer cells induces apoptosis via the mTOR/STAT3 pathway and suppresses tumor growth in mice. (2008) (114)
High-resolution tracking of cell division suggests similar cell cycle kinetics of hematopoietic stem cells stimulated in vitro and in vivo. (2000) (113)
Isolation in a single step of a highly enriched murine hematopoietic stem cell population with competitive long-term repopulating ability. (1989) (110)
Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells. (2011) (110)
High-level β-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells (2004) (110)
Clonal hematopoiesis demonstrated by X-linked DNA polymorphisms after allogeneic bone marrow transplantation. (1989) (109)
Separation of functionally distinct subpopulations of primitive human hematopoietic cells using rhodamine-123. (1991) (109)
High-resolution whole genome tiling path array CGH analysis of CD34+ cells from patients with low-risk myelodysplastic syndromes reveals cryptic copy number alterations and predicts overall and leukemia-free survival. (2008) (108)
Selective expansion of primitive normal hematopoietic cells in cytokine-supplemented cultures of purified cells from patients with chronic myeloid leukemia. (1997) (105)
Methodology of long-term culture of human hemopoietic cells (1991) (104)
Optimization of retroviral-mediated gene transfer to human NOD/SCID mouse repopulating cord blood cells through a systematic analysis of protocol variables. (1999) (104)
Unique effects of Stat3 on the early phase of hematopoietic stem cell regeneration. (2006) (104)
Cancer stem cells: Here, there, everywhere? (2008) (104)
Common and distinct features of cytokine effects on hematopoietic stem and progenitor cells revealed by dose–response surface analysis (2002) (103)
Steel factor responsiveness regulates the high self-renewal phenotype of fetal hematopoietic stem cells. (2007) (103)
Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice. (2013) (102)
Intermittent Exposure of Primitive Quiescent Chronic Myeloid Leukemia Cells to Granulocyte-Colony Stimulating Factor In vitro Promotes their Elimination by Imatinib Mesylate (2006) (101)
High‐resolution cell division tracking demonstrates the Flt3‐ligand‐dependence of human marrow CD34+CD38− cell production in vitro (1997) (100)
Engraftment of NOD/SCID-beta2 microglobulin null mice with multilineage neoplastic cells from patients with myelodysplastic syndrome. (2004) (99)
Studies of W mutant mice provide evidence for alternate mechanisms capable of activating hematopoietic stem cells. (1996) (97)
Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells (2015) (97)
BCR/ABL and other kinases from chronic myeloproliferative disorders stimulate single-strand annealing, an unfaithful DNA double-strand break repair. (2008) (97)
Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex. (2011) (96)
Improved purification of hematopoietic stem cells based on their elevated aldehyde dehydrogenase activity (2007) (94)
Alternative mechanisms with and without steel factor support primitive human hematopoiesis. (1993) (93)
Retrovirus-mediated gene transfer to purified hemopoietic stem cells with long-term lympho-myelopoietic repopulating ability. (1989) (92)
Expansion in vitro of retrovirally marked totipotent hematopoietic stem cells. (1990) (92)
Quantitation of the quiescent fraction of long-term culture-initiating cells in normal human blood and marrow and the kinetics of their growth factor-stimulated entry into S-phase in vitro. (1995) (90)
Telomere Length Dynamics in Normal Individuals and in Patients with Hematopoietic Stem Cell‐Associated Disorders (2001) (89)
DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts (2014) (89)
Profiling YB-1 target genes uncovers a new mechanism for MET receptor regulation in normal and malignant human mammary cells (2009) (89)
MCP-1, not MIP-1alpha, is the endogenous chemokine that cooperates with TGF-beta to inhibit the cycling of primitive normal but not leukemic (CML) progenitors in long-term human marrow cultures. (1998) (89)
Deciphering the Mammary Epithelial Cell Hierarchy (2006) (88)
High-efficiency gene transfer to human hematopoietic cells maintained in long-term marrow culture. (1989) (88)
Familial bone marrow monosomy 7. Evidence that the predisposing locus is not on the long arm of chromosome 7. (1989) (88)
Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1–BCR-ABL–JAK2 Complex (2013) (88)
Erythropoietin (Ep) dose-response curves for three classes of erythroid progenitors in normal human marrow and in patients with polycythemia vera. (1978) (87)
Differentiation-associated changes in CD44 isoform expression during normal hematopoiesis and their alteration in chronic myeloid leukemia. (1995) (87)
Preselection of retrovirally transduced bone marrow avoids subsequent stem cell gene silencing and age-dependent extinction of expression of human beta-globin in engrafted mice. (2000) (87)
Long-term marrow culture of cells from patients with acute myelogenous leukemia. Selection in favor of normal phenotypes in some but not all cases. (1985) (87)
Analysis of Normal Human Mammary Epigenomes Reveals Cell-Specific Active Enhancer States and Associated Transcription Factor Networks. (2016) (86)
Childhood myelodysplasia: suggested classification as myelodysplastic syndromes based on laboratory and clinical findings. (1990) (86)
Lonafarnib reduces the resistance of primitive quiescent CML cells to imatinib mesylate in vitro (2005) (85)
Impaired steel factor responsiveness differentially affects the detection and long-term maintenance of fetal liver hematopoietic stem cells in vivo. (1997) (82)
Aldehyde Dehydrogenase Activity Is a Biomarker of Primitive Normal Human Mammary Luminal Cells (2012) (80)
A method for obtaining high quality chromosome preparations from single hemopoietic colonies on a routine basis. (1981) (79)
Characterization of a primitive erythropoietic progenitor found in mouse marrow before and after several weeks in culture. (1979) (78)
Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions. (2007) (76)
Kinetics of in vivo homing and recruitment into cycle of hematopoietic cells are organ-specific but CD44-independent (2000) (74)
ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status. (2004) (74)
Hierarchical organization of fetal and adult hematopoietic stem cells. (2014) (74)
Ex vivo treatment of proliferating human cord blood stem cells with stroma-derived factor-1 enhances their ability to engraft NOD/SCID mice. (2002) (74)
Unique differentiation programs of human fetal liver stem cells shown both in vitro and in vivo in NOD/SCID mice. (1999) (73)
Developmental changes in hematopoietic stem cell properties (2013) (73)
Rapid and efficient selection of human hematopoietic cells expressing murine heat-stable antigen as an indicator of retroviral-mediated gene transfer. (1996) (73)
Liver and marrow of adult mdr-1a/1b(-/-) mice show normal generation, function, and multi-tissue trafficking of primitive hematopoietic cells. (2002) (71)
Retroviral gene transfer to primitive normal and leukemic hematopoietic cells using clinically applicable procedures. (1992) (71)
NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species (2012) (71)
CD44 isoforms in normal and leukemic hematopoiesis. (1999) (71)
Sustained high-level reconstitution of the hematopoietic system by preselected hematopoietic cells expressing a transduced cell-surface antigen. (1997) (70)
High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells. (2004) (70)
Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets (2014) (70)
Cell culture studies in CML. (1987) (68)
Steel factor coordinately regulates the molecular signature and biologic function of hematopoietic stem cells. (2008) (68)
During ontogeny primitive (CD34(+)CD38(-)) hematopoietic cells show altered expression of a subset of genes associated with early cytokine and differentiation responses of their adult counterparts. (2000) (67)
Clonal analysis via barcoding reveals diverse growth and differentiation of transplanted mouse and human mammary stem cells. (2014) (66)
Human growth factor-enhanced regeneration of transplantable human hematopoietic stem cells in nonobese diabetic/severe combined immunodeficient mice. (1999) (66)
The biology of normal and neoplastic stem cells in CML. (1993) (66)
RANK Signaling Amplifies WNT-Responsive Mammary Progenitors through R-SPONDIN1 (2015) (65)
Rapid differentiation of a rare subset of adult human lin(-)CD34(-)CD38(-) cells stimulated by multiple growth factors in vitro. (1999) (64)
Cytogenetic studies of early myeloid progenitor compartments in Ph1‐positive chronic myeloid leukaemia (CML) I. PERSISTENCE OF Ph1‐NEGATIVE COMMITTED PROGENITORS THAT ARE SUPPRESSED FROM DIFFERENTIATING IN VIVO (1984) (64)
Quantitation and characterization of human megakaryocyte colony‐forming cells using a standardized serum‐free agarose assay (1997) (64)
Partial characterization of a novel stromal cell-derived pre-B-cell growth factor active on normal and immortalized pre-B cells. (1988) (63)
Cytogenetic studies of early myeloid progenitor compartments in Ph1- positive chronic myeloid leukemia. II. Long-term culture reveals the persistence of Ph1-negative progenitors in treated as well as newly diagnosed patients (1984) (62)
The human hematopoietic stem cell in vitro and in vivo. (1992) (62)
Familial and congenital polycythemia in three unrelated families. (1992) (62)
Overexpression of a dominant negative form of STAT3 selectively impairs hematopoietic stem cell activity (2002) (61)
BCR-ABL expression in different subpopulations of functionally characterized Ph+ CD34+ cells from patients with chronic myeloid leukemia. (1996) (61)
Differential and synergistic effects of human granulocyte-macrophage colony-stimulating factor and human granulocyte colony-stimulating factor on hematopoiesis in human long-term marrow cultures. (1991) (61)
High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations (2018) (61)
Unfulfilled promise of endostatin in a gene therapy-xenotransplant model of human acute lymphocytic leukemia. (2002) (60)
Enhanced normal short-term human myelopoiesis in mice engineered to express human-specific myeloid growth factors. (2013) (60)
Differentiation stage-specific regulation of primitive human hematopoietic progenitor cycling by exogenous and endogenous inhibitors in an in vivo model. (1999) (60)
Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate. (2010) (59)
Molecular Analysis of Primitive Hematopoietic Cell Proliferation Control Mechanisms a (1991) (58)
Developmental Changes in the in Vitro Activated Regenerative Activity of Primitive Mammary Epithelial Cells (2013) (58)
Modulation of p210(BCR-ABL) activity in transduced primary human hematopoietic cells controls lineage programming. (2002) (58)
Transplantation of patients with high risk acute myeloid leukemia in first remission with autologous marrow cultured in interleukin-2 followed by interleukin-2 administration. (1994) (57)
New insights in biology and current therapeutic options for patients with chronic myelogenous leukemia. (1997) (57)
The tetrapeptide AcSDKP specifically blocks the cycling of primitive normal but not leukemic progenitors in long-term culture: evidence for an indirect mechanism. (1994) (56)
Acute myeloid leukemia and the Wnt pathway. (2010) (56)
BCR – ABL accelerates C2-ceramide-induced apoptosis (1998) (56)
Peripheral blood stem cells reach new heights [editorial; comment] (1993) (56)
Changes in the Proliferative Activity of Human Hematopoietic Stem Cells in NOD/SCID Mice and Enhancement of Their Transplantability after In Vivo Treatment with Cell Cycle Inhibitors (2002) (55)
Deregulated expression in Ph+ human leukemias of AHI-1, a gene activated by insertional mutagenesis in mouse models of leukemia. (2004) (55)
High marrow seeding efficiency of human lymphomyeloid repopulating cells in irradiated NOD/SCID mice. (2000) (55)
Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita. (2008) (55)
Heterogeneity of neoplastic stem cells: theoretical, functional, and clinical implications. (2013) (54)
Defective regulation of leukemic hematopoiesis in chronic myeloid leukemia. (1998) (54)
Phenotypic heterogeneity of primitive leukemic hematopoietic cells in patients with chronic myeloid leukemia. (1992) (54)
The Luminal Progenitor Compartment of the Normal Human Mammary Gland Constitutes a Unique Site of Telomere Dysfunction (2013) (53)
Characterization of Mouse Hematopoietic Stem and Progenitor Cells (2008) (53)
Evidence for a positive role of SHIP in the BCR-ABL-mediated transformation of primitive murine hematopoietic cells and in human chronic myeloid leukemia. (2003) (53)
Modeling the process of human tumorigenesis (2017) (53)
Expression of CD34 on human B cell precursors (1991) (52)
Production of granulocyte-macrophage colony-stimulating factor by Abelson virus-induced tumorigenic mast cell lines. (1986) (52)
Purification of hematopoietic stem cells for further biological study. (1999) (51)
Distinct Stromal Cell Factor Combinations Can Separately Control Hematopoietic Stem Cell Survival, Proliferation, and Self-Renewal (2014) (51)
Individual BFU-E in polycythemia vera produce both erythropoietin dependent and independent progeny. (1983) (50)
Abnormal erythropoiesis in the myeloproliferative disorders: an analysis of underlying cellular and humoral mechanisms. (1980) (50)
Molecular Decoy to the Y-Box Binding Protein-1 Suppresses the Growth of Breast and Prostate Cancer Cells whilst Sparing Normal Cell Viability (2010) (50)
Hematopoietic stem cells: Inferences from in vivo assays (1997) (50)
The marrow homing efficiency of murine hematopoietic stem cells remains constant during ontogeny. (2003) (48)
Malignant progenitors from patients with acute myelogenous leukemia are sensitive to a diphtheria toxin-granulocyte-macrophage colony-stimulating factor fusion protein. (1998) (48)
Diverse effects of anti‐CD44 antibodies on the stromal cell‐mediated support of normal but not leukaemic (CML) haemopoiesis in vitro (1997) (47)
Two classes of primitive pluripotent hemopoietic progenitor cells: Separation by adherence (1985) (46)
Nonclonal hemopoietic progenitor cells detected in long-term marrow cultures from a Turner syndrome mosaic with chronic myeloid leukemia (1984) (45)
Meta-Analysis of Differentiating Mouse Embryonic Stem Cell Gene Expression Kinetics Reveals Early Change of a Small Gene Set (2006) (45)
Focal Adhesion Kinase Splice Variants Maintain Primitive Acute Myeloid Leukemia Cells Through Altered Wnt Signaling (2012) (44)
Primitive interleukin 3 null hematopoietic cells transduced with BCR-ABL show accelerated loss after culture of factor-independence in vitro and leukemogenic activity in vivo. (2002) (44)
Enzymatic dissociation and culture of normal human mammary tissue to detect progenitor activity. (2005) (44)
Probing the mitotic history and developmental stage of hematopoietic cells using single telomere length analysis (STELA). (2008) (44)
Enhanced generation of hematopoietic cells from human hepatocarcinoma cell-stimulated human embryonic and induced pluripotent stem cells. (2009) (44)
Human Milk Protein Production in Xenografts of Genetically Engineered Bovine Mammary Epithelial Stem Cells (2010) (43)
Nonclonal hemopoietic progenitors in a G6PD heterozygote with chronic myelogenous leukemia revealed after long‐term marrow culture (1987) (43)
Granulocyte-macrophage colony-stimulating factor modulation of the inhibitory effect of transforming growth factor-beta on normal and leukemic human hematopoietic progenitor cells. (1992) (43)
Clinical significance of long-term cultures of myeloid blood cells. (1987) (43)
Stem Cells and the Developing Mammary Gland (2013) (42)
Cellular determinants affecting the rate of cytokine in cultures of human hematopoietic cells. (1997) (42)
Large-scale production of SAGE libraries from microdissected tissues, flow-sorted cells, and cell lines. (2006) (42)
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia. (1998) (41)
Lack of evidence for abnormal autocrine or paracrine mechanisms underlying the uncontrolled proliferation of primitive chronic myeloid leukemia progenitor cells. (1991) (41)
Amplification of Sca-1+ Lin-WGA+ cells in serum-free cultures containing steel factor, interleukin-6, and erythropoietin with maintenance of cells with long-term in vivo reconstituting potential (1994) (41)
Advances in hematopoietic stem cell culture. (1998) (40)
Altered patterns of CD44 epitope expression in human chronic and acute myeloid leukemia. (1996) (40)
Differential effects of granulocyte colony-stimulating factor on marrow- and blood-derived hematopoietic and immune cell populations in healthy human donors. (2004) (40)
Comparison of natural killer activity of human bone marrow and blood cells in cultures containing IL-2, IL-7 and IL-12. (1996) (39)
Nucleosome Density ChIP-Seq Identifies Distinct Chromatin Modification Signatures Associated with MNase Accessibility. (2016) (39)
Modeling human hematopoietic cell development from pluripotent stem cells. (2012) (39)
Genomic instability of human mammary epithelial cells overexpressing a truncated form of EMSY. (2005) (38)
Regulation of primitive human hematopoietic cells in long-term marrow culture. (1991) (37)
Functional assays for human embryonic stem cell pluripotency. (2011) (37)
Erythropoiesis in culture. (1984) (37)
Differences between normal and cml stem cells: Potential targets for clinical exploitation (1998) (37)
CFU-S in individual erythroid colonies derived in vitro from adult mouse marrow (1979) (36)
High-efficiency retroviral transduction of mammalian cells on positively charged surfaces. (2000) (36)
Introduction to Stem Cell Biology in Vitro: Threshold to the Future (1999) (36)
PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+ human leukemia (2018) (36)
Quantitation of human mammary epithelial stem cells with in vivo regenerative properties using a subrenal capsule xenotransplantation assay (2010) (36)
Efficient retrovirus-mediated gene transfer to transplantable human bone marrow cells in the absence of fibronectin. (2000) (36)
Transformation-associated alterations in interactions between pre-B cells and fibronectin. (1990) (35)
Differential effects of microenvironmentally presented interleukin 3 versus soluble growth factor on primitive human hematopoietic cells. (1991) (35)
Single-cell analysis identifies a CD33+ subset of human cord blood cells with high regenerative potential (2018) (35)
BCR-ABL-transduced human cord blood cells produce abnormal populations in immunodeficient mice (2005) (35)
Retinoblastoma-binding proteins 4 and 9 are important for human pluripotent stem cell maintenance. (2011) (34)
Long-term culture-initiating cell assays for human and murine cells. (2002) (34)
Identification of novel small molecule inhibitors of centrosome clustering in cancer cells (2013) (34)
Distinct signaling programs control human hematopoietic stem cell survival and proliferation. (2017) (34)
Efficient marking of human cells with rapid but transient repopulating activity in autografted recipients. (2005) (34)
Molecular analysis of clonality and bcr rearrangements in Philadelphia chromosome-positive acute lymphoblastic leukemia. (1988) (33)
Identification of properties that can distinguish primitive populations of stromal-cell-responsive lympho-myeloid cells from cells that are stromal-cell-responsive but lymphoid-restricted and cells that have lympho-myeloid potential but are also capable of competitively repopulating myeloablated rec (1996) (32)
Peripheral blood stem cells reach new heights. (1993) (32)
Detection of breakpoint cluster region- negative and nonclonal hematopoiesis in vitro and in vivo after transplantation of cells selected in cultures of chronic myeloid leukemia marrow (1990) (32)
Quantitation of murine and human hematopoietic stem cells by limiting-dilution analysis in competitively repopulated hosts. (2002) (32)
Activation of multiple hemopoietic growth factor genes in Abelson virus-transformed myeloid cells. (1988) (32)
Growth Arrest Specific 2 Is Up-Regulated in Chronic Myeloid Leukemia Cells and Required for Their Growth (2014) (32)
Explanation of dose-rate and split-dose effects on mouse foot reactions using the same time factor. (1980) (32)
Human long-term culture initiating cell assay. (2013) (31)
Heterogeneity in hematopoietic stem cell populations: implications for transplantation (2013) (31)
Increased erythropoietin-receptor expression on CD34-positive bone marrow cells from patients with chronic myeloid leukemia. (1992) (30)
LongSAGE profiling of nine human embryonic stem cell lines (2007) (29)
Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13. (2014) (29)
Practical and theoretical considerations in the use of the mouse foot system to derive epithelial stem cell survival parameters. (1979) (29)
Functional identification of bovine mammary epithelial stem/progenitor cells (2009) (29)
A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation (2015) (29)
Disruption of IKAROS activity in primitive chronic-phase CML cells mimics myeloid disease progression. (2015) (29)
Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β‐thalassemia patient (2013) (29)
Fluorodeoxyuridine synchronization of hemopoietic colonies. (1987) (28)
Increased erythropoietin-receptor expression on CD34-positive bone marrow cells from patients with chronic myeloid leukemia (1992) (27)
Sorafenib treatment of FLT 3-ITD acute myeloid leukemia : favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D 835 mutation (2012) (27)
Cell division tracking and expansion of hematopoietic long-term repopulating cells (1999) (27)
Variable expression of features of normal and neoplastic stem cells in patients with thrombocytosis (1992) (27)
4 Stem cell kinetics (1997) (27)
Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy. (2020) (26)
Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice (2017) (25)
Design and validation of a clinically applicable culture procedure for the generation of interleukin-2 activated natural killer cells in human bone marrow autografts. (1993) (25)
A Dominant-Negative Isoform of IKAROS Expands Primitive Normal Human Hematopoietic Cells (2014) (25)
Isolation and assessment of long-term reconstituting hematopoietic stem cells from adult mouse bone marrow. (2007) (25)
Characterization of Human Hematopoietic Cells with Short‐Lived in Vivo Repopulating Activity (2001) (24)
A quantitative bioassay for erythropoietin, using mouse bone marrow. (1981) (24)
Stem Cells and the Future of Regenerative Medicine (2002) (24)
The challenges of targeting chronic myeloid leukemia stem cells. (2007) (24)
Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors. (2020) (24)
Juvenile monosomy 7 syndrome: evidence that the disease originates in a pluripotent hemopoietic stem cell. (1987) (23)
Expression of an anti-sickling beta-globin in human erythroblasts derived from retrovirally transduced primitive normal and sickle cell disease hematopoietic cells. (2004) (23)
Quantitation of primitive and lineage-committed progenitors in mobilized peripheral blood for prediction of platelet recovery post autologous transplant (2000) (23)
Stability of patient-specific features of altered DNA replication timing in xenografts of primary human acute lymphoblastic leukemia. (2017) (22)
Evidence for differences in the mechanisms by which antibodies against CD44 promote adhesion of erythroid and granulopoietic progenitors to marrow stromal cells (1998) (22)
Concentration-dependent internalization of a cytokine/cytokine receptor complex in human hematopoietic cells. (1999) (22)
Autonomous multi-lineage differentiation in vitro of primitive CD34+ cells from patients with chronic myeloid leukemia (2000) (22)
Regulation of p21 by TWIST2 contributes to its tumor-suppressor function in human acute myeloid leukemia (2014) (22)
Transient suppression of clonal hemopoiesis associated with pregnancy in a patient with a myeloproliferative disorder. (1988) (22)
Phenotypic analysis of human embryonic stem cells. (2007) (22)
Chronic Myeloid Leukemia : Biology and Treatment (2003) (22)
Basal-like Breast Cancers: From Pathology to Biology and Back Again (2018) (22)
Dissociation of Survival, Proliferation, and State Control in Human Hematopoietic Stem Cells (2017) (22)
The BRG1 Chromatin Remodeler Protects Against Ovarian Cysts, Uterine Tumors, and Mammary Tumors in a Lineage-Specific Manner (2012) (22)
GateFinder: projection-based gating strategy optimization for flow and mass cytometry (2018) (21)
Maintenance and proliferation control of primitive hemopoietic progenitors in long-term cultures of human marrow cells. (1988) (21)
CM Affi‐Gel Blue chromatography of human urine: a simple one‐step procedure for obtaining erythropoietin suitable for in vitro erythropoietic progenitor assays (1984) (21)
Leukemic Stem Cells of Chronic Phase CML Patients Consistently Display Very High BCR-ABL Transcript Levels and Reduced Responsiveness to Imatinib Mesylate in Addition to Generating a Rare Subset That Produce Imatinib Mesylate-Resistant Differentiated Progeny. (2004) (21)
Mass Cytometric Analysis Reveals Viable Activated Caspase-3+ Luminal Progenitors in the Normal Adult Human Mammary Gland. (2017) (21)
The miR-185/PAK6 Axis Predicts Therapy Response and Regulates Survival of Drug-Resistant Leukemic Stem Cells in CML. (2020) (21)
Molecular profiling reveals similarities and differences between primitive subsets of hematopoietic cells generated in vitro from human embryonic stem cells and in vivo during embryogenesis. (2008) (21)
Evidence that ceramide mediates the ability of tumor necrosis factor to modulate primitive human hematopoietic cell fates. (2000) (20)
UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells (2018) (20)
Distinct but phenotypically heterogeneous human cell populations produce rapid recovery of platelets and neutrophils after transplantation. (2012) (20)
Stem cell kinetics. (1997) (19)
Ontogeny stage-independent and high-level clonal expansion in vitro of mouse hematopoietic stem cells stimulated by an engineered NUP98-HOX fusion transcription factor. (2011) (19)
Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis (2022) (19)
Use of a sensitive bioimmunoabsorbent assay to isolate and characterize monoclonal antibodies to biologically active human erythropoietin. (1988) (19)
Quantitation, mobilization, and clinical use of long-term culture-initiating cells in blood cell autografts. (1995) (19)
Integrin β3 links therapy resistance and cancer stem cell properties (2014) (19)
Stem Cell Biomarkers in Chronic Myeloid Leukemia (2008) (19)
Biological strategies for the selective manipulation of normal and leukemic stem cells (1993) (18)
Ex vivo expansion of normal and chronic myeloid leukemic stem cells without functional alteration using a NUP98HOXA10homeodomain fusion gene (2012) (18)
Detection of breakpoint cluster region- negative and nonclonal hematopoiesis in vitro and in vivo after transplantation of cells selected in cultures of chronic myeloid leukemia marrow. (1990) (18)
Both cycling and noncycling primitive progenitors continue to be mobilized into the circulation during the leukapheresis of patients pretreated with chemotherapy and G‐CSF (1997) (18)
Manipulation of the hematopoietic stem cell in vitro. (1992) (18)
Differential ability of flt3-ligand, interleukin-11, and Steel factor to support the generation of B cell progenitors and myeloid cells from primitive murine fetal liver cells. (1997) (18)
Expression of the leukemic prognostic marker CD7 is linked to epigenetic modifications in chronic myeloid leukemia (2010) (18)
Expression of a human beta-globin transgene in erythroid cells derived from retrovirally transduced transplantable human fetal liver and cord blood cells. (2002) (18)
An approach to the management of chronic myeloid leukemia in British Columbia (2008) (18)
p53: A New Kingpin in the Stem Cell Arena (2009) (18)
Characterization of Epithelial Progenitors in Normal Human Palatine Tonsils and Their HPV16 E6/E7-Induced Perturbation (2015) (17)
Prolonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cells. (2011) (17)
PKCθ Regulates T-Cell Leukemia-Initiating Activity via Reactive Oxygen Species (2012) (17)
Abnormalities in the erythroid progenitor compartments in patients with chronic myelogenous leukemia (CML). (1979) (16)
Method of analysis to derive cell survival from observation of tissue damage following fractionated irradiation. (1979) (16)
Determination of normal human serum erythropoietin levels, using mouse bone marrow. (1981) (16)
Cytogenetic studies of early myeloid progenitor compartments in Ph1-positive chronic myeloid leukemia. II. Long-term culture reveals the persistence of Ph1-negative progenitors in treated as well as newly diagnosed patients. (1984) (16)
Clonal analysis of individual human embryonic stem cell differentiation patterns in microfluidic cultures. (2015) (15)
A randomized phase II study of BB‐10010: a variant of human macrophage inflammatory protein‐1α for patients receiving high‐dose etoposide and cyclophosphamide for malignant lymphoma and breast cancer (1997) (15)
Initiation of human mammary cell tumorigenesis by mutant KRAS requires YAP inactivation (2019) (15)
The elusive peripheral blood hemopoietic stem cell. (1993) (15)
Cell Fate Decisions in Malignant Hematopoiesis: Leukemia Phenotype Is Determined by Distinct Functional Domains of the MN1 Oncogene (2014) (15)
Growth autonomy and lineage switching in BCR-ABL-transduced human cord blood cells depend on different functional domains of BCR-ABL (2004) (14)
Transcriptional regulation of normal human mammary cell heterogeneity and its perturbation in breast cancer (2019) (14)
Differential manipulation of normal and chronic myeloid leukemia stem cell proliferation in vitro. (1994) (14)
Manipulating hematopoietic stem cell amplification with Wnt (2003) (14)
BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells (2017) (14)
A novel population of local pericyte precursor cells in tumor stroma that require Notch signaling for differentiation. (2015) (14)
Transcriptional regulation of normal human mammary cell heterogeneity and its perturbation in breast cancer (2019) (14)
Stem cell clonality -- theoretical concepts, experimental techniques, and clinical challenges. (2013) (14)
Culture purging in leukemia: past, present, and future. (1993) (14)
Whole-genome analysis reveals unexpected dynamics of mutant subclone development in a patient with JAK2-V617F-positive chronic myeloid leukemia. (2017) (14)
Cytogenetic studies of haemopoietic colonies from patients with an initial diagnosis of acute lymphoblastic leukaemia (1988) (13)
Mammary epithelial cells have lineage-rooted metabolic identities (2021) (13)
The future of mammary stem cell biology: the power of in vivo transplants (2008) (13)
Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity. (2018) (13)
SDF-1 tells stem cells to mind their P's and Z's. (2005) (13)
Isolation and Assessment of Single Long-Term Reconstituting Hematopoietic Stem Cells from Adult Mouse Bone Marrow. (2016) (13)
Primitive haematopoietic progenitors in the blood of patients with sickle cell disease appear to be endogenously mobilized. (2000) (13)
Autocrine production of pre-B-cell stimulating activity by a variety of transformed murine pre-B-cell lines. (1988) (12)
Slow receptor acquisition by NK cells regenerated in vivo from transplanted fetal liver or adult bone marrow stem cells. (2003) (12)
Evidence for a multistep pathogenesis in the generation of tumorigenic cell lines from hemopoietic colonies exposed to Abelson virus in vitro. (1987) (12)
A Modified Polymerase Chain Reaction‐Long Serial Analysis of Gene Expression Protocol Identifies Novel Transcripts in Human CD34+ Bone Marrow Cells (2007) (12)
Selective growth of freshly isolated human breast epithelial cells cultured at low concentrations in the presence or absence of bone marrow cells (1996) (12)
Hemopoietic stem cell characterization. (1992) (12)
Breast Cancers Activate Stromal Fibroblast-Induced Suppression of Progenitors in Adjacent Normal Tissue (2017) (12)
A topological view of human CD34+ cell state trajectories from integrated single-cell output and proteomic data. (2019) (12)
Autografting in chronic myeloid leukemia with cultured marrow. (1992) (12)
Characterization of Normal Human Breast Epithelial Cell Subpopulations Isolated by Fluorescence-Activated Cell Sorting and Their Clonogenic Growth In Vitro (2000) (11)
Ex vivo expansion of human and murine hematopoietic stem cells. (2002) (11)
3 Cytokines acting early in human haematopoiesis (1994) (11)
A human embryonic stem cell line adapted for high throughput screening (2013) (11)
Phenotype-independent DNA methylation changes in prostate cancer (2018) (11)
Dose dependence of pion RBE values for mouse foot skin reactions. (1981) (10)
Growth factor regulation of the maintenance and differentiation of human long-term culture-initiating cells (LTC-IC). (1993) (10)
Age-correlated protein and transcript expression in breast cancer and normal breast tissues is dominated by host endocrine effects (2020) (10)
Early production of human neutrophils and platelets posttransplant is severely compromised by growth factor exposure. (2016) (10)
A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells (2019) (10)
Genotypic and functional diversity of phenotypically defined primitive hematopoietic cells in patients with chronic myeloid leukemia. (2013) (10)
Ontogeny of the mouse hemopoietic system. (1985) (10)
Replication timing alterations in leukemia affect clinically relevant chromosome domains. (2019) (10)
Maintenance of normal and abnormal hemopoietic cell populations in long-term cultures of CML and AML marrow cells. (1985) (10)
Cell separation improves the sensitivity of detecting rare human normal and leukemic hematopoietic cells in vivo in NOD/SCID mice. (2000) (10)
Modeling Normal and Disordered Human Hematopoiesis. (2015) (10)
Tipping the balance: MTDH-SND1 curbs oncogene-induced apoptosis and promotes tumorigenesis. (2014) (10)
Environmental Requirements of Hematopoietic Progenitor Cells in Ex Vivo Expansion Systems (1999) (10)
Short-term repopulating cells with myeloid potential in human mobilized peripheral blood do not have a side population (SP) phenotype. (2006) (9)
The role of erythropoietin and other growth factors in transfusion medicine. (1991) (9)
Role of macrophage-colony-stimulating factor in regulating the accumulation and phenotype of tumor-associated macrophages (1997) (9)
Correlation of CD44 expression with proliferative activity of normal human breast epithelial cells in culture (1998) (9)
Plerixafor effectively mobilizes CD56bright NK cells in blood, providing an allograft predicted to protect against GVHD. (2018) (9)
Empirical models of the proliferative response of cytokine‐dependent hematopoietic cell lines (2004) (8)
Variable persistence of leukemic progenitor cells in long-term CML and AML marrow cultures. (1984) (8)
Lack of effect of hematopoietic growth factors on human breast epithelial cell growth in serum-free primary culture. (1994) (8)
Stage-specific alterations in serum levels of G-CSF in chronic myeloid leukaemia (2003) (8)
MYC-induced human acute myeloid leukemia requires a continuing IL-3/GM-CSF costimulus. (2020) (8)
Evidence of similar effects of short-term culture on the initial repopulating activity of mobilized peripheral blood transplants assessed in NOD/SCID-beta2microglobulin(null) mice and in autografted patients. (2005) (7)
Macrophages stimulate mammary stem cells (2018) (7)
Control of the hematopoietic stem cell state (2013) (7)
Long-term culture-initiating cell assay for mouse cells. (2013) (7)
Modification of BRCA1-associated breast cancer risk by HMMR overexpression (2022) (7)
Continuous activation of primitive hematopoietic cells in long‐term human marrow cultures containing irradiated tumor cells (1991) (7)
Regulation of hemopoietic progenitor cell proliferation. (1988) (7)
Analysis of BCR–ABL1 tyrosine kinase domain mutational spectra in primitive chronic myeloid leukemia cells suggests a unique mutator phenotype (2010) (7)
Molecular mechanisms regulating TNF-alpha production by tumor-associated macrophages. (1997) (7)
A novel triple purge strategy for eliminating chronic myelogenous leukemia (CML) cells from autografts (2006) (7)
Unregulated proliferation of primitive neoplastic progenitor cells in long-term polycythemia vera marrow cultures. (1988) (7)
Cytokines acting early in human haematopoiesis. (1994) (6)
Childhood Leukemias: Anatomy and physiology of hematopoiesis (2006) (6)
Nonlinear effects of radiation dose on donor-cell reconstitution by limited numbers of purified stem cells. (1995) (6)
Reversing clonality in leukemia. (1991) (6)
New Models to Investigate Mechanisms of Disease Genesis from Primitive BCR‐ABL+ Hematopoietic Cells (2003) (6)
Allografting in chronic myeloid leukemia with cultured marrow: Update of the vancouver study (1993) (6)
Nonclonal hemopoietic progenitor cells detected in long-term marrow cultures from a Turner syndrome mosaic with chronic myeloid leukemia. (1984) (6)
Deregulated expression of HOXB 4 enhances the primitive growth activity of human hematopoietic cells (2002) (6)
Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia (2019) (6)
Feasibility of using autologous transplantation to evaluate hematopoietic stem cell-based gene therapy strategies in transgenic mouse models of human disease. (2002) (5)
SDF-1 And tgf-β enhance the detection of transplantable human stem cells regenerating in nod/scid mice (2000) (5)
MYC-induced human acute myeloid leukemia requires a continuing IL3/GM-CSF co-stimulus. (2020) (5)
In vitro culture of bone marrow cells for autografting in CML. (1993) (5)
A randomized phase II study of BB-10010: a variant of human macrophage inflammatory protein-1alpha for patients receiving high-dose etoposide and cyclophosphamide for malignant lymphoma and breast cancer. (1997) (5)
Blast colonies containing hemopoietic progenitor cells can give rise to Abelson virus (A-MuLV)-transformed cell lines. (1988) (5)
Characterization, quantitation and mobilization of early hematopoietic progenitors: implications for transplantation. (1996) (5)
Gene transfer into hematopoietic cells. Response (1990) (5)
Primitive haematopoietic progenitors in the blood of patients with sickle cell disease appear to be endogenously mobilized (2000) (5)
Fundamental Control of Hematopoiesis (1992) (5)
Marrow flask cultures -- a system for examining early erythropoietic differentiation events. (1979) (5)
Response to Comment on “PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+ human leukemia” (2019) (4)
Molecular mechanisms regulating TNF-α production by tumor-associated macrophages (1997) (4)
Leukemic Stem Cells of Chronic Phase CML Patients Possess Uniquely Elevated BCR-ABL Kinase Activity and Acquire Spontaneous BCR-ABL Kinase Domain Mutations at a High Frequency. (2005) (4)
Erythropoietic cells. (1984) (4)
A Prospective Analysis of Human Leukemogenesis (2018) (4)
Regulatory activity of endogenous MIP-1 alpha in long-term cultures of human marrow. (1994) (4)
Very high concentrations of cytokines are required for the maximal stimulation in vitro of primitive human hematopoietic progenitors and are depleted most rapidly by subpopulations of cells that are highly enriched in their LTC-IC content (1995) (4)
Suppresses Tumor Growth in Mice Cells Induces Apoptosis via the mTOR / STAT 3 Pathway and Targeting YB-1 in HER-2 Overexpressing Breast Cancer (2008) (4)
Regulate the Cell Cycle Status of Very Primitive Hematopoietic Cells in Long-Term Human Marrow Cultures . 11 . Analysis of Positive and Negative Regulators Produced by Stromal Cells Within the Adherent Layer (2003) (4)
Two functionally distinct epithelial progenitors exist within the luminal cell compartment of the mouse mammary gland (2008) (4)
A JAK/STAT-Mediated Inflammatory Signaling Cascade Drives Oncogenesis In AF10-Rearranged AML (2020) (3)
Differentially Expressed and Novel Transcripts in Highly Purified Chronic Phase CML Stem Cells (2008) (3)
The inherent differentiation program of short-term hematopoietic repopulating cells changes during human ontogeny. (2010) (3)
Mammary epithelial cells have lineage-restricted metabolic identities (2019) (3)
Inhibition of Let-7 Processing in Adult Murine Hematopoietic Stem Cells Induces a Fetal-Like High Self-Renewal Pattern in Their Progeny (2011) (3)
Preclinical Evaluation of a Bone-Marrow Autograft Culture Procedure for Generating Lymphokine-Activated Killer Cells in Vitro (1992) (3)
Notch-Mediated Suppression of PKCθ Reduces Reactive Oxygen Species and Promotes Leukemic Stem Cell Activity In T-Cell Acute Lymphoblastic Leukemia (T-ALL) (2010) (3)
Characterization of monoclonal antibodies to epithelial antigens expressed on breast cancer cells and absent on hematopoietic cells (1995) (3)
Time Course Studies of the Progeny of Barcoded CD34+ Human Cord Blood Cells Generated in Transplanted NOD/SCID-IL2Rγ−/− Mice Unveil the Clonal Dynamics of Short Term, Intermediate Term and Long Term Repopulating Cells (2012) (3)
Whole Genome Sequencing Of Chronic Myeloid Leukemia (CML)-Derived Induced Pluripotent Stem Cells (iPSC) Reveals Faithful Genocopying Of Highly Mutated Primary Leukemic Cells (2013) (3)
Long-term deregulated human hematopoiesis in goats transplanted in utero with BCR-ABL-transduced lin−CD34+ cord blood cells (2013) (3)
Colony stimulating factors. (1988) (3)
Quantitation of Human Cells that Produce Neutrophils and Platelets in Vivo Obtained from Normal Donors Treated with Granulocyte Colony-Stimulating Factor and/or Plerixafor. (2016) (3)
Overexpression of HOXA 10 perturbs human lymphomyelopoiesis in vitro and in vivo (2001) (3)
Changes in the cytokine regulation of stem cell self‐renewal during ontogeny (1998) (3)
A Novel Triple Purge Strategy for Eliminating Chronic Myelogenous Leukemia (CML) Cells from Autografts. (2004) (3)
G-CSF as a Potent Mitogen Augments the Elimination of CML Stem Cells by Imatinib Mesylate In Vitro . (2004) (3)
Erythroid progenitor cell numbers in human marrow - implications for regulation. (1979) (3)
Behavior of human leukemic progenitor populations in long-term marrow culture. (1985) (3)
Restricted expression of a new acute myelogenous leukemia-associated antigen (NHL-30.5) on normal hemopoietic progenitor cells. (1986) (3)
CML leukapheresis products can be enriched for CD34+ cells and simultaneously depleted of CD15+ cells using a simple Ab cocktail. (2002) (3)
Phenotypic characterization of mouse mammary epithelial stem and progenitor cells (2006) (3)
Clonal Origin in Normal Adults of All Blood Lineages and Circulating Hematopoietic Stem Cells. (2020) (2)
Hematopoietic stem cells get closer to the bone (2004) (2)
Targeting Rac2 - Mitochondrial Respiratory Chain Complex III Signaling to Prevent Genomic Instability in Leukemia Stem and Progenitor Cells (2011) (2)
Single-cell analysis of autophagy activity in normal and de novo transformed human mammary cells (2020) (2)
Pathogenic BRCA1 variants disrupt PLK1-regulation of mitotic spindle orientation (2022) (2)
Identification of New microRNA Biomarkers and Candidate Target Genes in Primitive CML Cells Using Global Comparative RNA analyses (2014) (2)
Role of STAT3 for hematopoietic stem cells (2002) (2)
Differential expression of homeobox genes in functionally distinct CD 34 + subpopulations of human bone marrow cells ( cDNA / hematopoiesi / Hox genes / reverse transcription PCR / stem cell-specdfc genes ) (2004) (2)
Enhanced and Accelerated Repopulation of Mutant C-Kit Immunodeficient Mice By Transplants of Primary Chronic and Acute Myeloid Leukemic Human Cells (2016) (2)
and differentiation responses of their adult counterparts altered expression of a subset of genes associated with early cytokine ) hematopoietic cells show − CD 38 + During ontogeny primitive ( CD 34 (2000) (2)
Autologous Transplantation in Patients with Acute Myeloid Leukemia in First Remission with IL-2-Cultured Marrow or Peripheral Blood Stem Cells Followed by in vivo IL-2 (1995) (2)
Growth control in leukemia. (1990) (2)
Inhibition of Mitochondrial Translation As a Therapeutic Strategy for Acute Myeloid Leukemia (AML) (2011) (2)
Transplantation of Immunodeficient Mice with Chronic Myeloid Leukemia (CML) Cells from Chronic Phase Patients Reveals a Hierarchy of CD34+ Aldehyde Dehydrogenase-Positive Cells with Short- and Long-Term Repopulating Activity and Transient Responsiveness to Imatinib Mesylate in Vivo. (2004) (2)
TEL me all. (2009) (2)
Identification of key microRNAs as predictive biomarkers of Nilotinib response in chronic myeloid leukemia: a sub-analysis of the ENESTxtnd clinical trial (2022) (2)
Sorafenib treatment of FLT 3-ITD + acute myeloid leukemia : favorable initial outcome and mechanisms of subsequent non-responsiveness associated with the emergence of a D 835 mutation Short-title : New D 835 clone in sorafenib treated FLT 3-ITD + AML (2012) (2)
The Focal Adhesion Complex Ilk-Pinch-Parvin Is Key to Niche Interactions and Survival of Quiescent Stem Cells in Chronic Myeloid Leukemia In Vitro and In Vivo (2016) (2)
Chronic Myeloid Leukemia Stem Cells Possess Unique Properties That Predict Intrinsic and Acquired Resistance to Imatinib Mesylate. (2006) (2)
Dominant-negative IKAROS enhances IL-3-stimulated signaling in wild-type but not BCR-ABL1(+) mouse BA/F3 cells. (2015) (2)
Clonal Origin in Normal Adults of All Blood Lineages and Circulating Hematopoietic Stem Cells (2019) (1)
50-FOLD Enrichment of CD34+ cells directly from cord blood in a single density separation (2000) (1)
Polycomb contraction differentially regulates terminal human hematopoietic differentiation programs (2019) (1)
Effects of hematopoietic growth factors on nonhematopoietic cells. (1992) (1)
Isolation and analysis of different subpopulations of normal human breast epithelial cells early after their infection with a retroviral vector encoding a cell surface marker (1997) (1)
Targeting Y-box binding protein-1 (YB-1) in Her-2 over-expressing breast cancer cells induces apoptosis via the signal transducer and activator or transcription-3 (STAT3) pathway and suppresses tumor growth. (2008) (1)
Single Cell-Resolution Analysis of HSC Dysfunction in Mir-146a knockout Mice (2017) (1)
Replication timing alterations in leukemia reflect stable clinically-relevant changes in genome architecture (2019) (1)
A simple three-step purification procedure for interleukin 3 involving absorption to fixed cells. (1989) (1)
Combined Targeting of BCR-ABL and JAK2 with ABL and JAK2 Inhibitors Is Effective Against CML Patients' Leukemic Stem/Progenitor Cells. (2010) (1)
Epigenetic and functional changes imposed by NUP98-HOXA9 in a genetically engineered model of chronic myeloid leukemia progression. (2020) (1)
A fond farewell to Ernest A. McCulloch--a beacon who inspired generations of scientists and framed the foundation of modern stem cell biology. (2011) (1)
Abstract 3459: BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells (2017) (1)
Letter The future of mammary stem cell biology: the power of in vivo (2008) (1)
Polycomb contraction differentially regulates terminal human hematopoietic differentiation programs (2022) (1)
Very primitive hematopoietic cells in normal adult human blood and marrow show differences in the regulation of their cycling state (1995) (1)
A Novel Strategy for Expanding Primitive Leukemic Cells from Chronic Phase CML Patients by Forced Overexpression of a NUP98-HOXA10 Homeodomain Fusion Gene. (2008) (1)
Reduction in multi-lineage and erythroid progenitors distinguishes myelodysplastic syndromes from non-malignant cytopenias. (2009) (1)
Abstract A63: Clonal analysis of normal and malignant human mammary epithelial cell responsiveness to radiation (2016) (1)
Resource Characterization of Epithelial Progenitors in Normal Human Palatine Tonsils and Their HPV 16 E 6 / E 7-Induced Perturbation (2015) (1)
miR-146a regulates hematopoietic stem cell maintenance and cell cycle entry (2013) (1)
New insights on clonal growth in vivo from barcoded transplants (2014) (1)
A JAK/STAT-MEDIATED INFLAMMATORY SIGNALING CASCADE DRIVES ONCOGENESIS IN AF10-REARRANGED AML. (2021) (1)
Variable Retention of Differentiation-specific DNA Replication Timing in Human Pediatric Leukemia (2019) (1)
Response : Discrete stem cell subsets (2006) (1)
MN1 Overexpression Promotes Proliferation and Self-Renewal of Primitive Normal Human Hematopoietic Cells (2008) (1)
Pions for radiotherapy at TRIUMF. (1980) (1)
Comprehensive Profiling of Micrornas in Murine Hematopoietic Stem Cells and Lineages Using a Microfluidics Approach (2008) (1)
Comparative Transcriptome Analysis of Different Subsets of CD34+ Normal and Chronic Myeloid Leukemia Cells Identifies Novel Perturbations in the CML Stem Cell Population. (2007) (1)
Rapiddecline ofchronic myeloid leukemic cells inlong-term culture duetoadefect attheleukemic stemcell level (hematopoletic stemcells/self-renewal/hematopoiesis) (1992) (1)
Molecular and biological analysis of human hematopoietic stem cells at single-cell resolution (2017) (1)
Expression of a human (cid:1) -globin transgene in erythroid cells derived from retrovirally transduced transplantable human fetal liver and cord blood cells (2002) (1)
Cancer Stem Cells: Notes for Authors (2020) (1)
Abstract 3887: A screen for new cancer specific drugs that target centrosome clustering (2012) (1)
Hematologic and immunologic changes in hairy cell leukemia patients treated with alpha interferon. (1988) (1)
De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer (2021) (1)
Unexpectedly High Self-Renewal Capacity Demonstrable by Serial Transplantation Is a Property of a Subset of Normal Adult Mouse Hematopoietic Stem Cells. (2004) (0)
New Candidate Regulators of Hematopoietic Stem Cells Identified from Transcriptional Comparisons of Highly Purified Populations of Longterm Repopulating Cells with Markedly Different in Vivo Self-Renewal Activities (2008) (0)
Disruption Of Ikaros In Patients’ Chronic Phase CML Cells Induces The Features Of Accelerated Phase Disease (2013) (0)
bone marrow cells in the absence of fibronectin Efficient retrovirus-mediated gene transfer to transplantable human (2013) (0)
Growth Factor-Dependent Activation of a MYC-Induced Latent AML Program in Human Hematopoietic Cells (2019) (0)
YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER (2018) (0)
Fetal Vs. Adult Hematopoietic Progenitors Respond Differently to NOTCH1: Implications for Pediatric Vs. Adult T-ALL. (2012) (0)
Early Appearance and Rapid, Selective Expansion of Lymphoid-Deficient Fetal HSCs Associated with Their Preferential Localization in the Marrow (2011) (0)
Abstract 1949: Caspase 3 plays a requisite role in regulating survival of human breast cancer cells (2021) (0)
The origin of blood cells: A matter of life and death (1997) (0)
hematopoietic cells controls lineage programming Modulation of p210BCR-ABL activity in transduced primary human (2013) (0)
B. Erythropoietic Cells (1984) (0)
Human Cord Blood Cells with Rapid In Vivo Platelet Regenerating Activity in NOD/SCID-IL-2Rγc-/- Mice Show Variable Aldehyde Dehydrogenase Activity. (2009) (0)
Identification of a Key Co-Operative Role of YB-1 in the Genesis and Metastasis of Human Breast Cancer (2019) (0)
Unregulated proliferation ofprimitive chronic myeloid leukemia progenitors inthepresence ofnormalmarrowadherent cells (1986) (0)
Analysis of hematopoietic cells generated from human induced pluripotent stem cells differentiating in teratomas (2016) (0)
modulate primitive human hematopoietic cell fates Evidence that ceramide mediates the ability of tumor necrosis factor to (2013) (0)
Methylation analysis of x linked genes reveals persisting monoclonal hemopoiesis of donor origin after allogeneic marrow transplantation (1988) (0)
and discovery in human embryonic stem cells Application of massively parallel sequencing to microRNA profiling Material Supplemental (2008) (0)
1032 - PROSPECTIVE ANALYSIS OF THE HUMAN LEUKEMOGENIC PROCESS (2019) (0)
Discrete stem cells : subsets or a continuum? Authors' reply (2006) (0)
A Fond Salute to George Stamatoyannopoulos - Scholar Leader Mentor Colleague Friend. (2018) (0)
Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia (2019) (0)
Integrin-Linked Kinase As a Key Mediator of Stromal Cell-Enhanced Resistance of Primitive CML Cells to Tyrosine Kinase Inhibitors (2014) (0)
mutation outcome and mechanisms of subsequent non-responsiveness associated acute myeloid leukemia : favorable initial + Sorafenib treatment of FLT 3-ITD (2012) (0)
19 – Distinct ROS Control Mechanisms and their Mutagenic Consequences in Progenitor Subsets of Normal Human Mammary Gland (2013) (0)
Ontogeny-related functional changes in very primitive hematopoietic cells (1995) (0)
Abstract 4258: Influence of lifestyle factors on adipocyte size in human breast tissue (2017) (0)
Cfu-s content of macroscopic erythroid bursts produced by adult bone marrow. Abstr. (1979) (0)
Phenotype-independent DNA methylation changes in prostate cancer (2018) (0)
Identification and Characterization of New Microrna Biomarkers and Target Genes in Drug-Insensitive CD34+ CML Stem/Progenitor Cells Using Global Comparative RNA-Seq Analyses (2015) (0)
O-13 Hematopoietic stem cells in normaland preleukemic disease states (2005) (0)
Hemopoietic growth factor regulation in malignant hemopoiesis (1997) (0)
Spontaneous reactivation of primitive quiescent cml cells is associated with upregulation of IL-3 expression (2000) (0)
Balancing work and life: an interview with Connie Eaves. (2009) (0)
Roles of microrna miR-146a in hematopoietic stem cell function (2017) (0)
Differences in the Transcriptomes of Highly Purified Fetal Liver and Adult Bone Marrow Hematopoietic Stem Cells Revealed by Long Serial Analysis of Gene Expression (LongSAGE) (2007) (0)
High-Resolution CGH Analysis of CD34+ Cells from Lower-Risk Myelodysplastic Patients Reveals Cryptic Copy Number Alterations and Predicts Overall and Leukemia-Free Survival. (2007) (0)
Identification of Novel Genes and Candidate Targets in CML Stem Cells (2008) (0)
dyskeratosis congenita Characterization of primitive hematopoietic cells from patients with (2013) (0)
3105 – ENHANCED OUTPUT OF PRIMITIVE HEMATOPOIETIC CELL PHENOTYPES IN TERATOMAS GENERATED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) IN MORE PERMISSIVE IMMUNODEFICIENT MICE (2020) (0)
Generation of a new de novo model of human AML from C-MYC-transduced normal human CD34+ cord blood cells transplanted into NRG-3/GM-CSF/S mice (2016) (0)
Longterm Multilineage Human Hematopoietic Repopulation of Untreated KIT-Mutant Immunodeficient Mice (2014) (0)
Abstract 125: First report of a full spectrum of de novo induced human breast cancer subtypes generated from oncogene-transduced freshly isolated normal human mammary cells (2021) (0)
Constitutive expression of the homeobox transcription factor HOXB4 amplifies human primitive hematopoietic progenitor cells in vitro and in vivo (2001) (0)
Diphtheria toxin fused to human gm-csf is toxic to primary malignant progenitors from patients with AML, JMML and CMML (1998) (0)
Rapid and Irreversible Alteration of the Ability of Hematopoietic Stem Cells To Execute Both Symmetric and Asymmetric Self-Renewal Divisions by Exposure to Reduced Steel Factor Concentrations with No Effect on Their Survival or Mitogenesis. (2006) (0)
Experimental hematology transitions forward again with new leadership and great expectations. (2023) (0)
Global Transcriptome Profiling Identifies a Key Mir-185-PAK6 Axis That Promotes Survival of Leukemic Stem Cells and Drug-Insensitive Blasts in BCR-ABL+ Human Leukemia (2018) (0)
Global Transcriptome Profiling Identifies a Key Mir-185-PAK6 Axis That Promotes Survival of Leukemic Stem Cells and Drug-Insensitive Blasts in BCR-ABL+ Human Leukemia (2018) (0)
Chronic Myeloid Leukemia Cytokine-Supplemented Cultures of Purified Cells From Patients With Selective Expansion of Primitive Normal Hematopoietic Cells in (2011) (0)
Multi-Tissue, Long-Term Engraftment and Expansion of BCR-ABL- transduced Human Lin - CD34 + Cord Blood Cells in a Large Animal Model. (2009) (0)
A Novel TWIST2-ID2 Axis That Modulates The Growth and Imatinib Sensitivity Of CML CD34+ Cells (2013) (0)
Tessa Laurie Holyoake, (March 17, 1963 – August 30, 2017): Remembering a life that knew no boundaries (2017) (0)
chromosome-positive acute lymphoblastic leukemia Molecular analysis of clonality and bcr rearrangements in Philadelphia (2011) (0)
Characterization of hematopoietic cells generated from normal and leukemic human induced pluripotent stem cells (hiPSCs) in teratomas (2017) (0)
Reply to 'Reassessing the human mammary stem cell concept by modeling limiting dilution transplantation assays' (2009) (0)
Single-Cell Analysis of Human B Lymphoid and Neutrophil/Monocyte Lineage Restriction (2021) (0)
Abstract IA13: Clonal dynamics of normal and malignant human mammary cell growth in xenografts (2016) (0)
Growth factor regulation of normal hematopoiesis (1995) (0)
High-level b-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells (2018) (0)
3039 – CLONAL TRACKING OF HUMAN B LYMPHOID AND NEUTROPHIL/MONOCYTE LINEAGE RESTRICTION (2021) (0)
A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation (2015) (0)
1009 Targeting Chronic Myeloid Leukemia Stem/progenitor Cells by Effective Inhibition of a Novel AHI-1-BCR-ABL-JAK2 Interaction Complex (2012) (0)
Role of serum erythropoietin, erythropoietin-independent erythroid colony formation, and bone marrow assessment in the diagnosis of polycythemia vera in patients with JAK2 V617F mutation. (2009) (0)
Prior Granulocyte Colony-Stimulating Factor Treatment Enhances the Immediate and Transient Output of Primitive Hematopoietic Cells in the Blood of Normal Adult Human Donors Treated with Plerixafor (2014) (0)
Developmental downregulation of LIN28 and HMGA2 expression in primitive normal human hematopoietic cells (2014) (0)
Stem Cell Repor ts Cancer Stem Cells: Notes for Authors (2020) (0)
Phenotypic and functional analyses of hematopoietic stem cells from murine adult bone marrow versus fetal liver reveal discrepancies between the in vivo and in vitro proliferative and self-renewal properties (1995) (0)
Differential Expression of Mirna Species in Cancer and the Contribution of MiR-223 to the Development of Acute Myeloid Leukemia. (2009) (0)
Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones (2018) (0)
Properties of CD34 + CML Cells That Predict Clinical Response to Tyrosine Kinase Inhibitors. (2007) (0)
Identification of two discrete patterns of hematopoietic stem cell differentiation that are reproducibly accompanied by extensive self-renewal potential (2007) (0)
NUP98-HOXA9-Initiates Molecular and Biologic Features of Disease Progression in a Humanized Model of CML (2019) (0)
A NUP98-HOX Fusion Gene Containing the Homeodomain of HOXA10 Promotes Significant Expansion of Primitive Human Hematopoietic Cells in Extended Cultures. (2006) (0)
Kongressbericht – Congress Report (1995) (0)
In Vitro Expansion of Human Hematopoietic Cells with Delayed but Sustained Multi-Lineage Repopulating Activity (2011) (0)
Ex vivo expansion of hematopoietic stem cells for use in nonmyeloablative transplantation (2008) (0)
3169 – ONCOGENE CONTRIBUTIONS IN A SYNTHETIC MODEL OF DE NOVO GENERATED HUMAN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (2019) (0)
Blood Stem Cells: A Simple Concept, but a Complex Reality (2018) (0)
Analysis of BCR ABL1 Tyrosine Kinase Domain Mutations In Primitive Chronic Myeloid Leukemia Cells Identifies a Unique Mutator Phenotype (2010) (0)
Demonstration of a permanent line of self-renewing mutli- potential hematopoietic stem cells in vitro. Abstr. (1981) (0)
Post-natal conservation of human blood and marrow-specific CD34+ hematopoietic phenotypes. (2022) (0)
Investigations of Murine Embryonic Stem Cell Maintenance by Analyses of Culture Variables and Gene Expression (2007) (0)
3125 – IDENTIFICATION OF CULTURE CONDITIONS THAT SUSTAIN THE IN VIVO REGENERATIVE PROPERTIES OF A NEW SUBSET OF HUMAN FETAL LIVER HEMATOPOIETIC STEM CELLS (2022) (0)
Detection of IL-3 and g-csf mRNA and protein in CD34+ progenitor cells and serum from cml patients (2000) (0)
"Hematopoietic Stem Cells: Mechanisms of Heterogeneity and Transformation" (2012) (0)
Genotypic Representation of Myelodysplastic/Myeloproliferative Neoplasms in Nrg, Nrg-3GS and Srg-W41 Mice with Transgenic Expression of Human Cytokines (2018) (0)
Distinct Human Cell Populations Produce Rapidly Detectable Levels of Neutrophils and Platelets in NOD/SCID-IL-2Receptor Gamma Chain Null Mice Transgenically Engineered to Produce Human Myeloid Growth Factors (2011) (0)
Therapeutic Effect of HOXB4-Expanded Stem Cells in Mice with Beta Thalassemia Given a Non-Myeloablative Conditioning Regimen. (2006) (0)
New Fine Structure within the Adult Hematopoietic Stem Cell Compartment Revealed by Longterm Analysis of Mice Repopulated with Single Cells or Their In Vitro Generated Clonal Progeny. (2005) (0)
Loss of Primitive Hematopoietic Cells in Patients with Dyskeratosis Congenita. (2007) (0)
Quantitation of the Quiescent Fraction of Long-Term Culture-In Cells in Normal Human Blood and Marrow and the Kinetics of Growth Factor-Stimulated Entry Into S-Phase In Vitro itiating Their (2016) (0)
3013 – AGE-ASSOCIATED DIFFERENCES IN HUMAN HEMATOPOIETIC STEM CELL PROLIFERATION CONTROL REVEALED BY A NOVEL MULTIPARAMETER SINGLE-CELL ANALYSIS APPROACH (2020) (0)
Identification of a New Population of Human Cord Blood Cells with Lymphoid-Restricted Reconstituting Potential in Sublethally Irradiated Immunodeficient Mice. (2004) (0)
Short Term Signalling Responses of the Most Primitive Subsets of Human Hematopoietic Cells Stimulated in Vitro Correlate with Their Subsequent Self-Renewal Behaviour. (2012) (0)
Direct evidence that stromal derived factor-1 inhibits the proliferation of human hemopoietic stem cells in NOD/SCID mice (2002) (0)
Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scidyscid mice (hematopoietic stem cellsytransplantationyin vitro cell expansion) (1997) (0)
Abstract 2919: Different ROS control mechanisms and mutagenic consequences in primitive subsets of normal human mammary cells. (2013) (0)
cells retrovirally transduced transplantable human fetal liver and cord blood -globin transgene in erythroid cells derived from β Expression of a human (2013) (0)
Stromal Cell Regulation of Murine Hematopoietic Stem Cells. (2010) (0)
Interactions between primitive hematopoietic cells and bone marrow stroma (1997) (0)
retroviral-mediated gene transfer expressing murine heat-stable antigen as an indicator of Rapid and efficient selection of human hematopoietic cells (2010) (0)
Abstract B45: De novo generation of highly aggressive human breast tumors by rapid serial passaging of oncogene-transduced starting populations of purified normal cells (2016) (0)
Targeting ILK impairs TKI-resistance of quiescent leukemic stem cells in vitro and in vivo (2017) (0)
Regulators of human stem cell proliferation and engraftment (2002) (0)
Modeling Normal and Disordered Human (2015) (0)
The focal adhesion protein ilk is key to niche interactions and survival of CML stem cells (2015) (0)
Factors and hemopoiesis: Pandora's box revisited. (1984) (0)
Conservation of human hematopoietic CD34+ phenotypes during aging (2022) (0)
Aging alters the cell cycle control and mitogenic signaling responses of human hematopoietic stem cells. (2023) (0)
Differences In the Short Term Granulocyte and Platelet Producing Activity of Cord Blood and Mobilized Peripheral Blood Transplants Revealed by Quantitative Repopulation Assays In NOD/SCID-IL-2Rγc−/− Mice. (2010) (0)
362 - Elevated ROS Activates KIT, a Lineage-Specific Signaling Receptor in Normal Human Mammary Epithelial Cells (2014) (0)
Single Cell Immune Profiling Reveals Distinct T Cell Clones and Functional States in in-Vitro Expanded Cord Blood Derived Gamma Delta T Cells (2020) (0)
De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer (2021) (0)
Abstract A23: Human mammary luminal progenitor cells use cKIT-H2O2 interactions to regulate their growth (2016) (0)
Modeling of Hematopoietic Stem Cell Response to Cytokines (2001) (0)
DNA barcoded competitive clone-initiating cell analysis reveals novel features of metastatic growth in a cancer xenograft model (2022) (0)
Pyrimido-Indole Derivatives Are Novel Agonists of Human Cord Blood Hematopoietic Stem Cell Self-Renewal (2014) (0)
Differential Activation of V γ4V δ1 and V γ9V δ2 Cord Blood Derived Gamma Delta T Cells upon Exposure to EBV-Lcl and K562 Cells (2021) (0)
The Reduced Lymphopoietic Potential of a Novel Subclass of Hematopoietic Stem Cells Is Mediated by Specific Defects In the Production and Activity of Their Common Lymphoid Progenitor (CLP) Progeny (2010) (0)
Comparative RNA-seq analyses identify new microRNA biomarkers and candidate target genes in patients’ drug-resistant CD34+ CML stem/progenitor cells (2015) (0)
Wilsede-Schule für Onkologie und Hämatologie – Wilsede School for Oncology and Hematology (1995) (0)
Comparative RNA-seq analyses identify new microRNA biomarkers and candidate target genes in patients’ drug-resistant CD34+ CML stem/progenitor cells (2015) (0)
Development of a Clinically Relevant in Vitro Drug Screening Platform for Chemo-Refractory AML Patients (2014) (0)
HOXA10-Overexpression causes severe perturbations in human hematopoiesis (2000) (0)
Autografting with Cultured Marrow for the Myeloid Leukemias: The Vancouver Experience (2020) (0)
YB-1 Is Critical For The Genesis And Progression Of KRAS Mutated Human Breast Cancer (2018) (0)
progenitors genomic instability in chronic myeloid leukemia stem cells and primitive mitochondrial respiratory chain complex III-generated ROS cause - Rac2 (2012) (0)
Immunotherapy in Marrow Transplantation — Interferon Early after Transplantation or IL-2-Activated Bone Marrow (1994) (0)
High Resolution Time-Lapse Monitoring of Individual Hematopoietic Stem Cells Reveals New Biomarkers of Self-Renewal. (2005) (0)
High Resolution Time-Lapse Monitoring of Individual Hematopoietic Stem Cells Reveals New Biomarkers of Self-Renewal. (2005) (0)
Message from the Editor. (2018) (0)
Yeast Deletion Mutants Systematic Genetic Analysis with Ordered Arrays (2007) (0)
growth factor-stimulated entry into S-phase in vitro cells in normal human blood and marrow and the kinetics of their Quantitation of the quiescent fraction of long-term culture-initiating (2011) (0)
Evidence That High-Mobility Group A2 (Hmga2) Expression Contributes to the Ontogeny-Dependent Properties of Fetal Hematopoietic Stem Cells. (2010) (0)
Clonal Analysis of Mouse Mammary Luminal Epithelial Cell Transplants. (2019) (0)
Marrow and in Patients with Polycythemia Vera (2016) (0)
Single-cell analysis identifies a CD33+ subset of human cord blood cells with high regenerative potential (2018) (0)
Purification and characterization of hematopoietic stem and progenitor cells (1994) (0)
Quantitative Assays for Human Hemopoietic Progenitor Cells (2020) (0)
Generation of a new, human growth factor-dependent, de novo model of AML from c-MYC-transduced normal human CD34+ hematopoietic cells (2017) (0)
fetal hematopoietic stem cells Steel factor responsiveness regulates the high self-renewal phenotype of (2013) (0)
Longterm Serial Transplantability of BCR-ABL+ Chronic Phase CML Cells Is Predicted by a 6-Week LTC-IC Assay. (2012) (0)
NOTCH1 Induces Differential Epigenomic Patterning and Genomic Organization in Fetal Liver- and Adult Bone Marrow-Derived Hematopoietic Progentiors (2015) (0)
Most of the Short Term Repopulating Cells in Human Mobilized Peripheral Blood Do Not Have a Side Population (SP) Phenotype. (2004) (0)
Unexpected and Sustained Symmetry in the Repopulation Programs Displayed by Clonally Amplified Hematopoietic Stem Cells. (2006) (0)
Brief an die Herausgeber · Letter to the Editors (2009) (0)

This paper list is powered by the following services:

Other Resources About Connie Eaves

en.wikipedia.org

What Schools Are Affiliated With Connie Eaves?

Connie Eaves is affiliated with the following schools:

Connie Eaves's Academic­Influence.com Rankings