Cornelis Murre

Q: What Schools Are Affiliated With Cornelis Murre

Cornelis Murre is affiliated with the following schools: University of Amsterdam, University of California, San Diego, Vanderbilt University, Massachusetts Institute of Technology, Harvard University

Cornelis Murre's AcademicInfluence.com Rankings

Cornelis Murre

Biology

#9398

World Rank

#12599

Historical Rank

Molecular Biology

#1283

World Rank

#1310

Historical Rank

Biochemistry

#1433

World Rank

#1557

Historical Rank

biology Degrees

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Biology

Cornelis Murre's Degrees

PhD Molecular Biology University of Amsterdam
Masters Biochemistry University of Amsterdam
Bachelors Chemistry University of Amsterdam

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Cornelis Murre's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. (2010) (8812)
A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins (1989) (2387)
Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence (1989) (1736)
Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic Organisms (2000) (1725)
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements (1994) (849)
Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo (1991) (830)
A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B all (1990) (706)
Structure and function of helix-loop-helix proteins. (1994) (504)
A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates the B cell fate (2010) (482)
E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas (1997) (428)
Helix-loop-helix proteins and lymphocyte development (2005) (340)
The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets (2011) (338)
Induction of Early B Cell Factor (EBF) and Multiple B Lineage Genes by the Basic Helix-Loop-Helix Transcription Factor E12 (1998) (301)
The 3D Structure of the Immunoglobulin Heavy-Chain Locus: Implications for Long-Range Genomic Interactions (2008) (300)
Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade (2001) (295)
CTCF Binding Elements Mediate Control of V(D)J Recombination (2011) (264)
E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells. (2000) (264)
extradenticle Raises the DNA binding specificity of homeotic selector gene products (1994) (263)
E-proteins directly regulate expression of activation-induced deaminase in mature B cells (2003) (261)
Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. (2000) (239)
Both E12 and E47 allow commitment to the B cell lineage. (1997) (239)
A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1. (1997) (237)
The function of E- and id proteins in lymphocyte development (2001) (228)
B Cell Super-Enhancers and Regulatory Clusters Recruit AID Tumorigenic Activity (2014) (227)
Global changes in nuclear positioning of genes and intra- and inter-domain genomic interactions that orchestrate B cell fate (2012) (210)
Early Thymocyte Development Is Regulated by Modulation of E2a Protein Activity (2001) (208)
E protein function in lymphocyte development. (2002) (207)
CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells (2011) (206)
E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment (2006) (203)
Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells. (2005) (203)
TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB. (2004) (201)
3D Trajectories Adopted by Coding and Regulatory DNA Elements: First-Passage Times for Genomic Interactions (2014) (194)
Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-β (2001) (193)
Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription (2004) (189)
Human γ-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7 (1985) (187)
Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate (2017) (184)
B-cell- and myocyte-specific E2-box-binding factors contain E12/E47-like subunits (1991) (176)
E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins (1993) (174)
A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells (1993) (168)
Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development. (2006) (162)
Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent. (2004) (161)
Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia. (1999) (161)
The gene for enhancer binding proteins E12/E47 lies at the t(1;19) breakpoint in acute leukemias. (1989) (160)
E2A activity is induced during B‐cell activation to promote immunoglobulin class switch recombination (1999) (155)
Chromatin Architecture and the Generation of Antigen Receptor Diversity (2009) (146)
FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development (2008) (138)
Thymocyte Maturation Is Regulated by the Activity of the Helix-Loop-Helix Protein, E47 (1999) (137)
E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors (2009) (135)
Mouse FGF15 is the ortholog of human and chick FGF19, but is not uniquely required for otic induction. (2004) (134)
The role of E2A-PBX1 in leukemogenesis (2001) (133)
Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia. (1993) (129)
Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors. (2011) (127)
Positive and Negative Regulation of V(D)J Recombination by the E2A Proteins (1999) (127)
E2A proteins: essential regulators at multiple stages of B‐cell development (2000) (122)
Localized Gene-Specific Induction of Accessibility to V(D)j Recombination Induced by E2a and Early B Cell Factor in Nonlymphoid Cells (2001) (120)
Neuronal Death and Perinatal Lethality in Voltage-Gated Sodium Channel αII-Deficient Mice (2000) (119)
E2A proteins enforce a proliferation checkpoint in developing thymocytes (2004) (119)
Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomas. (1999) (118)
Human T-cell gamma chain genes: organization, diversity, and rearrangement. (1986) (118)
Engrailed and Hox homeodomain proteins contain a related Pbx interaction motif that recognizes a common structure present in Pbx. (1996) (116)
Interplay between RORgammat, Egr3, and E proteins controls proliferation in response to pre-TCR signals. (2006) (116)
The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells (2011) (116)
The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins. (1995) (115)
The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells (1996) (115)
Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47. (2007) (109)
Receptor Editing and Marginal Zone B Cell Development Are Regulated by the Helix-Loop-Helix Protein, E2A (2004) (106)
Localization of E2A mRNA expression in developing and adult rat tissues. (1993) (106)
The role of E-proteins in B- and T-lymphocyte development. (1998) (104)
Ets proteins: new factors that regulate immunoglobulin heavy-chain gene expression (1993) (103)
Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease (2014) (103)
Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth (2015) (102)
Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci (2009) (96)
Chromatin topology and the regulation of antigen receptor assembly. (2012) (96)
Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice. (2000) (95)
Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate (2012) (95)
BCR-ABL-transformed GMP as myeloid leukemic stem cells (2008) (92)
Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation (1999) (90)
Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2 (1995) (87)
Faculty Opinions recommendation of Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development. (2009) (86)
The regulation and function of the Id proteins in lymphocyte development (2001) (86)
Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing (2020) (82)
Human T-cell γ genes contain N segments and have marked junctional variability (1986) (81)
Pbx raises the DNA binding specificity but not the selectivity of antennapedia Hox proteins (1997) (78)
T cell receptor gene rearrangements define a monoclonal T cell proliferation in patients with T cell lymphocytosis and cytopenia. (1986) (76)
The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor (2011) (75)
Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses (2020) (75)
Characterization of ABF-1, a Novel Basic Helix-Loop-Helix Transcription Factor Expressed in Activated B Lymphocytes (1998) (74)
Helix–loop–helix proteins and the advent of cellular diversity: 30 years of discovery (2019) (71)
β-Selection-induced proliferation is required for αβ T cell differentiation. (2012) (70)
Specific residues in the Pbx homeodomain differentially modulate the DNA-binding activity of Hox and Engrailed proteins. (1997) (70)
Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions (2019) (69)
IL‐7Rα and E47: independent pathways required for development of multipotent lymphoid progenitors (2002) (69)
The E‐Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development (2017) (67)
CCCTC‐Binding Factor Translates Interleukin 2‐ and &agr;‐Ketoglutarate‐Sensitive Metabolic Changes in T Cells into Context‐Dependent Gene Programs (2017) (65)
Comprehensive characterization of neutrophil genome topology (2017) (60)
E2A Deﬁciency Leads to Abnormalities in ab T-Cell Development and to Rapid Development of T-Cell Lymphomas (1997) (60)
Fgf15 is required for proper morphogenesis of the mouse cardiac outflow tract (2005) (59)
Disruption of pre-TCR expression accelerates lymphomagenesis in E2A-deficient mice (2002) (58)
Molecular organization of mammalian meiotic chromosome axis revealed by expansion STORM microscopy (2019) (58)
Transcription factor regulation of B lineage commitment. (2001) (54)
Dissection of serological and cytolytic T lymphocyte epitopes on murine major histocompatibility antigens by a recombinant H-2 gene separating the first two external domains (1984) (54)
Factors and networks that underpin early hematopoiesis. (2011) (52)
AID targeting: old mysteries and new challenges. (2015) (52)
New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors (2015) (52)
32 The Helix-Loop-Helix Motif: Structure and Function (1992) (51)
Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain. (1986) (51)
Dpbx, a new homeobox gene closely related to the human proto-oncogene pbxl molecular structure and developmental expression (1993) (50)
Induction of a Diverse T Cell Receptor γ/δ Repertoire by the Helix-Loop-Helix Proteins E2a and Heb in Nonlymphoid Cells (2001) (47)
The E–Id protein axis modulates the activities of the PI3K–AKT–mTORC1–Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis (2015) (40)
Localization of Pbx1 transcripts in developing rat embryos (1995) (39)
The establishment of B versus T cell identity. (2014) (38)
A novel mechanism of somatic rearrangement predicted by a human T-cell antigen receptor beta-chain complementary DNA. (1985) (38)
Transcription and recombination factories: common features? (2011) (35)
Helix-Loop-Helix Proteins (2002) (34)
c-jun inhibits insulin control element-mediated transcription by affecting the transactivation potential of the E2A gene products (1995) (34)
Regulation and function of the E2A proteins in B cell development. (2007) (30)
E2A and CBP/p300 Act in Synergy To Promote Chromatin Accessibility of the Immunoglobulin κ Locus (2012) (30)
DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection. (2005) (28)
The cellular Pax-Hox-helix connection. (2003) (28)
Biochemical and Phosphoproteomic Analysis of the Helix-Loop-Helix Protein E47 (2012) (28)
Differential Roles for the E2A Activation Domains in B Lymphocytes and Macrophages1 (2008) (28)
Transcription factors in hematopoiesis. (1999) (27)
Conformational changes induced in Hoxb-8/Pbx-1 heterodimers in solution and upon interaction with specific DNA (1997) (27)
Developmental trajectories in early hematopoiesis. (2009) (27)
Intertwining proteins in thymocyte development and cancer (2000) (27)
Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment (1986) (25)
A B-Cell-Specific Enhancer Orchestrates Nuclear Architecture to Generate a Diverse Antigen Receptor Repertoire. (2019) (24)
Calcium signaling instructs NIPBL recruitment at active enhancers and promoters via distinct mechanisms to reconstruct genome compartmentalization (2020) (22)
Human gamma-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7. (1985) (22)
The opposing roles of E2A and Id3 that orchestrate and enforce the naïve T cell fate (2011) (21)
FOXO1 constrains activation and regulates senescence in CD8 T cells. (2021) (20)
CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis (2019) (20)
Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program (2020) (18)
E2A gene products are not required for insulin gene expression. (1996) (16)
Id3 Orchestrates Germinal Center B Cell Development (2016) (16)
Cellular and chromatin dynamics of antibody‐secreting plasma cells (2016) (16)
Defining the pathways of early adult hematopoiesis. (2007) (15)
Differential expression of H-2Dd and H-2Ld histocompatibility antigens (1985) (14)
The E protein-TCF1 axis controls γδ T cell development and effector fate (2021) (12)
Plasma Cell Fate Is Orchestrated by Elaborate Changes in Genome Compartmentalization and Inter-chromosomal Hubs. (2020) (12)
Epigenetics of antigen-receptor gene assembly. (2007) (12)
Suppression of E-protein activity interferes with the development of BCR-ABL-mediated myeloproliferative disease (2008) (11)
AKR murine thymic leukemias are from a distinct thymic cell lineage and do not express the beta chain of the T-cell antigen receptor. (1986) (11)
Human T-cell gamma genes contain N segments and have marked junctional variability. (1986) (10)
Spatial Organization of Chromatin: Transcriptional Control of Adaptive Immune Cell Development (2021) (10)
Nuclear positioning rather than contraction controls ordered rearrangements of immunoglobulin loci (2015) (10)
Id Proteins Suppress E2A-Driven Invariant Natural Killer T Cell Development prior to TCR Selection (2018) (10)
The Helix-Loop-Helix Motif (1992) (10)
Ectopic expression of E 47 or E 12 promotes the death of E 2 A-deficient lymphomas (1999) (9)
β2-Microglobulin from serum associates with several class I antigens expressed on the surface of mouse L-cells (1985) (8)
Role of helix-loop-helix proteins in lymphocyte development. (1999) (7)
Ribosomal Proteins and the Control of αβ T Lineage Development (2007) (7)
Molecular determinants and heterogeneity of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing (2020) (6)
Molecular mechanisms that orchestrate the assembly of antigen receptor loci (2015) (6)
proteins and Notch signaling cooperate to promote T cell lineage specifi cation and commitment (2006) (6)
Pax1/E2a Double-Mutant Mice Develop Non-Lethal Neural Tube Defects that Resemble Human Malformations (2005) (6)
Ribosomal proteins and the control of alphabeta T lineage development. (2007) (5)
The Structure and Regulation of the Immunoglobulin Loci (2015) (5)
Nuclear location and the control of developmental progression. (2013) (4)
Plasma Cell Fate Is Orchestrated by Elaborate Changes in Genome Compartmentalization and Inter-chromosomal Hubs. (2020) (4)
An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells (2004) (4)
Direct observation of RAG recombinase recruitment to chromatin and the IgH locus in live pro-B cells (2020) (4)
A regulatory network of microRNAs confers lineage commitment during early developmental trajectories of B and T lymphocytes (2021) (3)
‘Big bang’ of B-cell development revealed (2018) (3)
Ldb1, a new guardian of hematopoietic stem cell maintenance (2011) (3)
CRISPR/Cas9 For Photoactivated Localization Microscopy (PALM) (2014) (3)
Differential Roles for the E 2 A Activation Domains in B Lymphocytes and Macrophages 1 (2008) (3)
Bursty gene expression and mRNA decay pathways orchestrate B cell activation (2021) (3)
Faculty Opinions recommendation of The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells. (2011) (2)
Marking Emerging - and ?d-Selected T Cells (2006) (2)
Ensuring an equal playing field for antigen receptor loci variable regions (2015) (2)
Nuclear geography and allelic exclusion (2008) (2)
Faculty Opinions recommendation of A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation. (2005) (2)
Boosting lymphocyte production. (2013) (2)
A proposed unified interphase nucleus chromosome structure: Preliminary preponderance of evidence (2021) (2)
A Common Mechanism that Underpins Antibody Diversification (2015) (2)
Reprogramming Committed B Lineage Cells (2004) (2)
Epigenetic Regulation of Lymphocyte Development (2012) (1)
A proposed unified mitotic chromosome architecture (2021) (1)
Upon microbial challenge human neutrophils undergo rapid changes in nuclear architecture to orchestrate an immediate inflammatory gene program (2019) (1)
Correction: FGF15 promotes neurnogenesis and opposes FGF8 function during neocortical development (2008) (1)
Zhu 1 Comprehensive characterization of neutrophil genome topology (2017) (1)
mTECs Aire on the side of caution (2018) (1)
Imatinib-Resistant Activation of β-Catenin by BCR-ABL in a Murine Model of Chronic Myelogenous Leukemia Stem Cells. (2006) (0)
The epigenetics of early lymphocyte development. (2013) (0)
Macrophages Domains in B Lymphocytes and Differential Roles for the E2A Activation (2008) (0)
Faculty Opinions recommendation of GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages. (2003) (0)
Faculty Opinions recommendation of Two forms of loops generate the chromatin conformation of the immunoglobulin heavy-chain gene locus. (2012) (0)
Abstract A182: Zbtb7b is involved in the association of EBF1 enhancer to the nuclear lamina during early B cell commitment (2016) (0)
Transcriptional control (SY4-4) Chairpersons: Toshinori Nakayama, Ellen Rothenberg (2010) (0)
Nuclear Architecture Controls the Timescales of Genomic Interactions (2018) (0)
Active maintenance of CD8+ T cell naïvety through regulation of global genome architecture (2023) (0)
Faculty Opinions recommendation of Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene. (2002) (0)
Intertwining Proteins Helix-Loop-Helix Transcription Factors By Trevor Littlewood and Gerard I. Evan Oxford: Oxford University Press (1998). 151 pp. $46.95 (1999) (0)
On the Border of Order: Chromosomal Organization in Space and Time (2019) (0)
Id proteins suppress E2A-driven innate-like T cell development prior to TCR selection (2017) (0)
Assays of Cell-mediated Cytotoxicity (2003) (0)
Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens (2023) (0)
Construction, expression and function of H-2 mutant and H-2 recombinant genes (1984) (0)
Faculty Opinions recommendation of Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus. (2009) (0)
Immunoglobulin Promote Chromatin Accessibility of the E 2 A and CBP / p 300 Act in Synergy To Murre and (2012) (0)
mTECs Aire on the side of caution (2018) (0)
Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions (2019) (0)
EtsProteins: New Factors ThatRegulate Immunoglobulin Heavy-Chain GeneExpression (1993) (0)
Correction (2015) (0)
E2A and the Development of B and T Lymphocytes (2002) (0)
proliferation in patients with T cell lymphocytosis and cytopenia T cell receptor gene rearrangements define a monoclonal T cell (2011) (0)
Faculty Opinions recommendation of Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection. (2004) (0)
Ensur ing an equal playing field for antigen receptor loci var iable reg ions (2015) (0)
orchestrate B cell fate. (2016) (0)
Antigen receptor locus dynamics is orchestrated near the sol-gel phase transition to enforce stepwise VDJ gene rearrangement (2018) (0)
Current Opinion in Immunology. Editorial overview. (2010) (0)
Regulating intertwining proteins. (2003) (0)
Faculty Opinions recommendation of Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. (2006) (0)
Marking emerging beta- and gammadelta-selected T cells. (2006) (0)
A HESitant decision for T cells (2013) (0)
The 3D Architecture and Dynamics of the Immunoglobin Heavy-Chain and other Loci and its Functional Implications for Genome Organization (2011) (0)
immunoglobulin heavy-chain gene expression. Ets proteins: new factors that regulate (2013) (0)
Helix-Loop-Helix Proteins in Adaptive Immune Development (2022) (0)
Global approaches to identify novel participants that modulate intestinal epithelial cell development. (2010) (0)

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What Schools Are Affiliated With Cornelis Murre?

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Why Is Cornelis Murre Influential?

Cornelis Murre's Published Works

Published Works

What Schools Are Affiliated With Cornelis Murre?

Cornelis Murre's AcademicInfluence.com Rankings