Cornelis Murre
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Cornelis Murrebiology Degrees
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Molecular Biology
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Biology
Cornelis Murre's Degrees
- PhD Molecular Biology University of Amsterdam
- Masters Biochemistry University of Amsterdam
- Bachelors Chemistry University of Amsterdam
Why Is Cornelis Murre Influential?
(Suggest an Edit or Addition)Cornelis Murre's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. (2010) (8812)
- A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins (1989) (2387)
- Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence (1989) (1736)
- Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic Organisms (2000) (1725)
- E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements (1994) (849)
- Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo (1991) (830)
- A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B all (1990) (706)
- Structure and function of helix-loop-helix proteins. (1994) (504)
- A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates the B cell fate (2010) (482)
- E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas (1997) (428)
- Helix-loop-helix proteins and lymphocyte development (2005) (340)
- The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets (2011) (338)
- Induction of Early B Cell Factor (EBF) and Multiple B Lineage Genes by the Basic Helix-Loop-Helix Transcription Factor E12 (1998) (301)
- The 3D Structure of the Immunoglobulin Heavy-Chain Locus: Implications for Long-Range Genomic Interactions (2008) (300)
- Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade (2001) (295)
- CTCF Binding Elements Mediate Control of V(D)J Recombination (2011) (264)
- E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells. (2000) (264)
- extradenticle Raises the DNA binding specificity of homeotic selector gene products (1994) (263)
- E-proteins directly regulate expression of activation-induced deaminase in mature B cells (2003) (261)
- Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. (2000) (239)
- Both E12 and E47 allow commitment to the B cell lineage. (1997) (239)
- A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1. (1997) (237)
- The function of E- and id proteins in lymphocyte development (2001) (228)
- B Cell Super-Enhancers and Regulatory Clusters Recruit AID Tumorigenic Activity (2014) (227)
- Global changes in nuclear positioning of genes and intra- and inter-domain genomic interactions that orchestrate B cell fate (2012) (210)
- Early Thymocyte Development Is Regulated by Modulation of E2a Protein Activity (2001) (208)
- E protein function in lymphocyte development. (2002) (207)
- CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells (2011) (206)
- E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment (2006) (203)
- Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells. (2005) (203)
- TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB. (2004) (201)
- 3D Trajectories Adopted by Coding and Regulatory DNA Elements: First-Passage Times for Genomic Interactions (2014) (194)
- Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-β (2001) (193)
- Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription (2004) (189)
- Human γ-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7 (1985) (187)
- Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate (2017) (184)
- B-cell- and myocyte-specific E2-box-binding factors contain E12/E47-like subunits (1991) (176)
- E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins (1993) (174)
- A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells (1993) (168)
- Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development. (2006) (162)
- Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent. (2004) (161)
- Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia. (1999) (161)
- The gene for enhancer binding proteins E12/E47 lies at the t(1;19) breakpoint in acute leukemias. (1989) (160)
- E2A activity is induced during B‐cell activation to promote immunoglobulin class switch recombination (1999) (155)
- Chromatin Architecture and the Generation of Antigen Receptor Diversity (2009) (146)
- FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development (2008) (138)
- Thymocyte Maturation Is Regulated by the Activity of the Helix-Loop-Helix Protein, E47 (1999) (137)
- E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors (2009) (135)
- Mouse FGF15 is the ortholog of human and chick FGF19, but is not uniquely required for otic induction. (2004) (134)
- The role of E2A-PBX1 in leukemogenesis (2001) (133)
- Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia. (1993) (129)
- Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors. (2011) (127)
- Positive and Negative Regulation of V(D)J Recombination by the E2A Proteins (1999) (127)
- E2A proteins: essential regulators at multiple stages of B‐cell development (2000) (122)
- Localized Gene-Specific Induction of Accessibility to V(D)j Recombination Induced by E2a and Early B Cell Factor in Nonlymphoid Cells (2001) (120)
- Neuronal Death and Perinatal Lethality in Voltage-Gated Sodium Channel αII-Deficient Mice (2000) (119)
- E2A proteins enforce a proliferation checkpoint in developing thymocytes (2004) (119)
- Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomas. (1999) (118)
- Human T-cell gamma chain genes: organization, diversity, and rearrangement. (1986) (118)
- Engrailed and Hox homeodomain proteins contain a related Pbx interaction motif that recognizes a common structure present in Pbx. (1996) (116)
- Interplay between RORgammat, Egr3, and E proteins controls proliferation in response to pre-TCR signals. (2006) (116)
- The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells (2011) (116)
- The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins. (1995) (115)
- The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells (1996) (115)
- Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47. (2007) (109)
- Receptor Editing and Marginal Zone B Cell Development Are Regulated by the Helix-Loop-Helix Protein, E2A (2004) (106)
- Localization of E2A mRNA expression in developing and adult rat tissues. (1993) (106)
- The role of E-proteins in B- and T-lymphocyte development. (1998) (104)
- Ets proteins: new factors that regulate immunoglobulin heavy-chain gene expression (1993) (103)
- Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease (2014) (103)
- Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth (2015) (102)
- Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci (2009) (96)
- Chromatin topology and the regulation of antigen receptor assembly. (2012) (96)
- Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice. (2000) (95)
- Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate (2012) (95)
- BCR-ABL-transformed GMP as myeloid leukemic stem cells (2008) (92)
- Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation (1999) (90)
- Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2 (1995) (87)
- Faculty Opinions recommendation of Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development. (2009) (86)
- The regulation and function of the Id proteins in lymphocyte development (2001) (86)
- Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing (2020) (82)
- Human T-cell γ genes contain N segments and have marked junctional variability (1986) (81)
- Pbx raises the DNA binding specificity but not the selectivity of antennapedia Hox proteins (1997) (78)
- T cell receptor gene rearrangements define a monoclonal T cell proliferation in patients with T cell lymphocytosis and cytopenia. (1986) (76)
- The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor (2011) (75)
- Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses (2020) (75)
- Characterization of ABF-1, a Novel Basic Helix-Loop-Helix Transcription Factor Expressed in Activated B Lymphocytes (1998) (74)
- Helix–loop–helix proteins and the advent of cellular diversity: 30 years of discovery (2019) (71)
- β-Selection-induced proliferation is required for αβ T cell differentiation. (2012) (70)
- Specific residues in the Pbx homeodomain differentially modulate the DNA-binding activity of Hox and Engrailed proteins. (1997) (70)
- Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions (2019) (69)
- IL‐7Rα and E47: independent pathways required for development of multipotent lymphoid progenitors (2002) (69)
- The E‐Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development (2017) (67)
- CCCTC‐Binding Factor Translates Interleukin 2‐ and &agr;‐Ketoglutarate‐Sensitive Metabolic Changes in T Cells into Context‐Dependent Gene Programs (2017) (65)
- Comprehensive characterization of neutrophil genome topology (2017) (60)
- E2A Deficiency Leads to Abnormalities in ab T-Cell Development and to Rapid Development of T-Cell Lymphomas (1997) (60)
- Fgf15 is required for proper morphogenesis of the mouse cardiac outflow tract (2005) (59)
- Disruption of pre-TCR expression accelerates lymphomagenesis in E2A-deficient mice (2002) (58)
- Molecular organization of mammalian meiotic chromosome axis revealed by expansion STORM microscopy (2019) (58)
- Transcription factor regulation of B lineage commitment. (2001) (54)
- Dissection of serological and cytolytic T lymphocyte epitopes on murine major histocompatibility antigens by a recombinant H-2 gene separating the first two external domains (1984) (54)
- Factors and networks that underpin early hematopoiesis. (2011) (52)
- AID targeting: old mysteries and new challenges. (2015) (52)
- New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors (2015) (52)
- 32 The Helix-Loop-Helix Motif: Structure and Function (1992) (51)
- Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain. (1986) (51)
- Dpbx, a new homeobox gene closely related to the human proto-oncogene pbxl molecular structure and developmental expression (1993) (50)
- Induction of a Diverse T Cell Receptor γ/δ Repertoire by the Helix-Loop-Helix Proteins E2a and Heb in Nonlymphoid Cells (2001) (47)
- The E–Id protein axis modulates the activities of the PI3K–AKT–mTORC1–Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis (2015) (40)
- Localization of Pbx1 transcripts in developing rat embryos (1995) (39)
- The establishment of B versus T cell identity. (2014) (38)
- A novel mechanism of somatic rearrangement predicted by a human T-cell antigen receptor beta-chain complementary DNA. (1985) (38)
- Transcription and recombination factories: common features? (2011) (35)
- Helix-Loop-Helix Proteins (2002) (34)
- c-jun inhibits insulin control element-mediated transcription by affecting the transactivation potential of the E2A gene products (1995) (34)
- Regulation and function of the E2A proteins in B cell development. (2007) (30)
- E2A and CBP/p300 Act in Synergy To Promote Chromatin Accessibility of the Immunoglobulin κ Locus (2012) (30)
- DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection. (2005) (28)
- The cellular Pax-Hox-helix connection. (2003) (28)
- Biochemical and Phosphoproteomic Analysis of the Helix-Loop-Helix Protein E47 (2012) (28)
- Differential Roles for the E2A Activation Domains in B Lymphocytes and Macrophages1 (2008) (28)
- Transcription factors in hematopoiesis. (1999) (27)
- Conformational changes induced in Hoxb-8/Pbx-1 heterodimers in solution and upon interaction with specific DNA (1997) (27)
- Developmental trajectories in early hematopoiesis. (2009) (27)
- Intertwining proteins in thymocyte development and cancer (2000) (27)
- Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment (1986) (25)
- A B-Cell-Specific Enhancer Orchestrates Nuclear Architecture to Generate a Diverse Antigen Receptor Repertoire. (2019) (24)
- Calcium signaling instructs NIPBL recruitment at active enhancers and promoters via distinct mechanisms to reconstruct genome compartmentalization (2020) (22)
- Human gamma-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7. (1985) (22)
- The opposing roles of E2A and Id3 that orchestrate and enforce the naïve T cell fate (2011) (21)
- FOXO1 constrains activation and regulates senescence in CD8 T cells. (2021) (20)
- CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis (2019) (20)
- Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program (2020) (18)
- E2A gene products are not required for insulin gene expression. (1996) (16)
- Id3 Orchestrates Germinal Center B Cell Development (2016) (16)
- Cellular and chromatin dynamics of antibody‐secreting plasma cells (2016) (16)
- Defining the pathways of early adult hematopoiesis. (2007) (15)
- Differential expression of H-2Dd and H-2Ld histocompatibility antigens (1985) (14)
- The E protein-TCF1 axis controls γδ T cell development and effector fate (2021) (12)
- Plasma Cell Fate Is Orchestrated by Elaborate Changes in Genome Compartmentalization and Inter-chromosomal Hubs. (2020) (12)
- Epigenetics of antigen-receptor gene assembly. (2007) (12)
- Suppression of E-protein activity interferes with the development of BCR-ABL-mediated myeloproliferative disease (2008) (11)
- AKR murine thymic leukemias are from a distinct thymic cell lineage and do not express the beta chain of the T-cell antigen receptor. (1986) (11)
- Human T-cell gamma genes contain N segments and have marked junctional variability. (1986) (10)
- Spatial Organization of Chromatin: Transcriptional Control of Adaptive Immune Cell Development (2021) (10)
- Nuclear positioning rather than contraction controls ordered rearrangements of immunoglobulin loci (2015) (10)
- Id Proteins Suppress E2A-Driven Invariant Natural Killer T Cell Development prior to TCR Selection (2018) (10)
- The Helix-Loop-Helix Motif (1992) (10)
- Ectopic expression of E 47 or E 12 promotes the death of E 2 A-deficient lymphomas (1999) (9)
- β2-Microglobulin from serum associates with several class I antigens expressed on the surface of mouse L-cells (1985) (8)
- Role of helix-loop-helix proteins in lymphocyte development. (1999) (7)
- Ribosomal Proteins and the Control of αβ T Lineage Development (2007) (7)
- Molecular determinants and heterogeneity of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing (2020) (6)
- Molecular mechanisms that orchestrate the assembly of antigen receptor loci (2015) (6)
- proteins and Notch signaling cooperate to promote T cell lineage specifi cation and commitment (2006) (6)
- Pax1/E2a Double-Mutant Mice Develop Non-Lethal Neural Tube Defects that Resemble Human Malformations (2005) (6)
- Ribosomal proteins and the control of alphabeta T lineage development. (2007) (5)
- The Structure and Regulation of the Immunoglobulin Loci (2015) (5)
- Nuclear location and the control of developmental progression. (2013) (4)
- Plasma Cell Fate Is Orchestrated by Elaborate Changes in Genome Compartmentalization and Inter-chromosomal Hubs. (2020) (4)
- An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells (2004) (4)
- Direct observation of RAG recombinase recruitment to chromatin and the IgH locus in live pro-B cells (2020) (4)
- A regulatory network of microRNAs confers lineage commitment during early developmental trajectories of B and T lymphocytes (2021) (3)
- ‘Big bang’ of B-cell development revealed (2018) (3)
- Ldb1, a new guardian of hematopoietic stem cell maintenance (2011) (3)
- CRISPR/Cas9 For Photoactivated Localization Microscopy (PALM) (2014) (3)
- Differential Roles for the E 2 A Activation Domains in B Lymphocytes and Macrophages 1 (2008) (3)
- Bursty gene expression and mRNA decay pathways orchestrate B cell activation (2021) (3)
- Faculty Opinions recommendation of The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells. (2011) (2)
- Marking Emerging - and ?d-Selected T Cells (2006) (2)
- Ensuring an equal playing field for antigen receptor loci variable regions (2015) (2)
- Nuclear geography and allelic exclusion (2008) (2)
- Faculty Opinions recommendation of A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation. (2005) (2)
- Boosting lymphocyte production. (2013) (2)
- A proposed unified interphase nucleus chromosome structure: Preliminary preponderance of evidence (2021) (2)
- A Common Mechanism that Underpins Antibody Diversification (2015) (2)
- Reprogramming Committed B Lineage Cells (2004) (2)
- Epigenetic Regulation of Lymphocyte Development (2012) (1)
- A proposed unified mitotic chromosome architecture (2021) (1)
- Upon microbial challenge human neutrophils undergo rapid changes in nuclear architecture to orchestrate an immediate inflammatory gene program (2019) (1)
- Correction: FGF15 promotes neurnogenesis and opposes FGF8 function during neocortical development (2008) (1)
- Zhu 1 Comprehensive characterization of neutrophil genome topology (2017) (1)
- mTECs Aire on the side of caution (2018) (1)
- Imatinib-Resistant Activation of β-Catenin by BCR-ABL in a Murine Model of Chronic Myelogenous Leukemia Stem Cells. (2006) (0)
- The epigenetics of early lymphocyte development. (2013) (0)
- Macrophages Domains in B Lymphocytes and Differential Roles for the E2A Activation (2008) (0)
- Faculty Opinions recommendation of GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages. (2003) (0)
- Faculty Opinions recommendation of Two forms of loops generate the chromatin conformation of the immunoglobulin heavy-chain gene locus. (2012) (0)
- Abstract A182: Zbtb7b is involved in the association of EBF1 enhancer to the nuclear lamina during early B cell commitment (2016) (0)
- Transcriptional control (SY4-4) Chairpersons: Toshinori Nakayama, Ellen Rothenberg (2010) (0)
- Nuclear Architecture Controls the Timescales of Genomic Interactions (2018) (0)
- Active maintenance of CD8+ T cell naïvety through regulation of global genome architecture (2023) (0)
- Faculty Opinions recommendation of Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene. (2002) (0)
- Intertwining Proteins Helix-Loop-Helix Transcription Factors By Trevor Littlewood and Gerard I. Evan Oxford: Oxford University Press (1998). 151 pp. $46.95 (1999) (0)
- On the Border of Order: Chromosomal Organization in Space and Time (2019) (0)
- Id proteins suppress E2A-driven innate-like T cell development prior to TCR selection (2017) (0)
- Assays of Cell-mediated Cytotoxicity (2003) (0)
- Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens (2023) (0)
- Construction, expression and function of H-2 mutant and H-2 recombinant genes (1984) (0)
- Faculty Opinions recommendation of Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus. (2009) (0)
- Immunoglobulin Promote Chromatin Accessibility of the E 2 A and CBP / p 300 Act in Synergy To Murre and (2012) (0)
- mTECs Aire on the side of caution (2018) (0)
- Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions (2019) (0)
- EtsProteins: New Factors ThatRegulate Immunoglobulin Heavy-Chain GeneExpression (1993) (0)
- Correction (2015) (0)
- E2A and the Development of B and T Lymphocytes (2002) (0)
- proliferation in patients with T cell lymphocytosis and cytopenia T cell receptor gene rearrangements define a monoclonal T cell (2011) (0)
- Faculty Opinions recommendation of Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection. (2004) (0)
- Ensur ing an equal playing field for antigen receptor loci var iable reg ions (2015) (0)
- orchestrate B cell fate. (2016) (0)
- Antigen receptor locus dynamics is orchestrated near the sol-gel phase transition to enforce stepwise VDJ gene rearrangement (2018) (0)
- Current Opinion in Immunology. Editorial overview. (2010) (0)
- Regulating intertwining proteins. (2003) (0)
- Faculty Opinions recommendation of Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. (2006) (0)
- Marking emerging beta- and gammadelta-selected T cells. (2006) (0)
- A HESitant decision for T cells (2013) (0)
- The 3D Architecture and Dynamics of the Immunoglobin Heavy-Chain and other Loci and its Functional Implications for Genome Organization (2011) (0)
- immunoglobulin heavy-chain gene expression. Ets proteins: new factors that regulate (2013) (0)
- Helix-Loop-Helix Proteins in Adaptive Immune Development (2022) (0)
- Global approaches to identify novel participants that modulate intestinal epithelial cell development. (2010) (0)
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