Craig D. Logsdon
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Philosophy
Craig D. Logsdon's Degrees
- PhD Cancer Biology Johns Hopkins University
- Bachelors Biology University of Maryland, College Park
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(Suggest an Edit or Addition)Craig D. Logsdon's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cancer-associated stromal fibroblasts promote pancreatic tumor progression. (2008) (1010)
- Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. (2009) (785)
- Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. (2003) (568)
- StellaTUM: current consensus and discussion on pancreatic stellate cell research (2011) (351)
- Roles for KRAS in pancreatic tumor development and progression. (2013) (332)
- Mechanism of glucocorticoid receptor down-regulation by glucocorticoids. (1988) (313)
- S100P Stimulates Cell Proliferation and Survival via Receptor for Activated Glycation End Products (RAGE)* (2004) (283)
- Molecular cloning of a gene encoding the histamine H2 receptor. (1991) (272)
- An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice. (2012) (243)
- S100P Promotes Pancreatic Cancer Growth, Survival, and Invasion (2005) (240)
- Glucocorticoids increase amylase mRNA levels, secretory organelles, and secretion in pancreatic acinar AR42J cells (1985) (233)
- Chemokine gene expression in rat pancreatic acinar cells is an early event associated with acute pancreatitis. (1997) (222)
- Silencing of the Hypoxia-Inducible Cell Death Protein BNIP3 in Pancreatic Cancer (2004) (222)
- Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization. (2009) (208)
- Differentiation of the Chloride Extrusion Mechanism During Seawater Adaptation of a Teleost Fish, The Cichlid Sarotherodon Mossambicus (1981) (204)
- NF-κB activation in pancreas induces pancreatic and systemic inflammatory response (2002) (203)
- RAGE and RAGE ligands in cancer. (2007) (196)
- Ras activity levels control the development of pancreatic diseases. (2009) (189)
- Activation of nuclear factor-κB in acinar cells increases the severity of pancreatitis in mice. (2013) (188)
- A high-fat diet activates oncogenic Kras and COX2 to induce development of pancreatic ductal adenocarcinoma in mice. (2013) (187)
- Cell surface lactate receptor GPR81 is crucial for cancer cell survival. (2014) (165)
- Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver. (2008) (163)
- Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer. (2008) (160)
- Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survival. (2008) (160)
- Dynamic mast cell-stromal cell interactions promote growth of pancreatic cancer. (2013) (159)
- CEACAM1, a Novel Serum Biomarker for Pancreatic Cancer (2007) (158)
- The immune system in cancer metastasis: friend or foe? (2017) (158)
- Effect of cromolyn on S100P interactions with RAGE and pancreatic cancer growth and invasion in mouse models. (2006) (153)
- A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis. (2012) (148)
- New insights into neurohormonal regulation of pancreatic secretion. (2004) (145)
- Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in β cells and mice. (2012) (143)
- Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice. (2011) (135)
- Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma (2011) (134)
- Human pancreatic acinar cells lack functional responses to cholecystokinin and gastrin. (2001) (134)
- Oncogenic K-Ras requires activation for enhanced activity (2014) (128)
- Stimulation of pancreatic acinar cell growth by CCK, epidermal growth factor, and insulin in vitro. (1986) (128)
- Nuclear factor-κB maintains TRAIL resistance in human pancreatic cancer cells (2006) (126)
- Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression. (2008) (126)
- Mast Cells in Tumor Microenvironment Promotes the In Vivo Growth of Pancreatic Ductal Adenocarcinoma (2011) (123)
- Pancreatic gene expression during the initiation of acute pancreatitis: identification of EGR-1 as a key regulator. (2003) (122)
- An Autoantibody-Mediated Immune Response to Calreticulin Isoforms in Pancreatic Cancer (2004) (117)
- A Transforming Growth Factor β-Induced Smad3/Smad4 Complex Directly Activates Protein Kinase A (2004) (117)
- S100P-Derived RAGE Antagonistic Peptide Reduces Tumor Growth and Metastasis (2012) (117)
- NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response. (2002) (115)
- Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis. (2006) (113)
- Nuclear Factor-κB p65/relA Silencing Induces Apoptosis and Increases Gemcitabine Effectiveness in a Subset of Pancreatic Cancer Cells (2008) (111)
- Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach (2019) (111)
- Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression (2012) (108)
- American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and Comparative Physiology American Journal of Physiology: Renal, Fluid and Electrolyte (2003) (108)
- Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis (2011) (106)
- Pancreatic acinar cells in culture: expression of acinar and ductal antigens in a growth-related manner. (1990) (105)
- Overexpressed Galectin-3 in Pancreatic Cancer Induces Cell Proliferation and Invasion by Binding Ras and Activating Ras Signaling (2012) (105)
- Glucocorticoids increase cholecystokinin receptors and amylase secretion in pancreatic acinar AR42J cells. (1986) (105)
- Jun Kinases Are Rapidly Activated by Cholecystokinin in Rat Pancreas both in Vitro and in Vivo(*) (1996) (103)
- The Molecular Basis of Pancreatic Fibrosis: Common Stromal Gene Expression in Chronic Pancreatitis and Pancreatic Adenocarcinoma (2004) (100)
- Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression (2007) (100)
- Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer. (2006) (96)
- The role of protein synthesis and digestive enzymes in acinar cell injury (2013) (93)
- Mechanisms of Insulin-Induced Insulin-Receptor Downregulation: Decrease of Receptor Biosynthesis and mRNA Levels (1989) (92)
- Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment. (2017) (91)
- Adrenomedullin is expressed in pancreatic cancer and stimulates cell proliferation and invasion in an autocrine manner via the adrenomedullin receptor, ADMR. (2007) (91)
- Dual Targeting of Endothelial Cells and Pericytes in Antivascular Therapy for Ovarian Carcinoma (2007) (91)
- Down-regulation of ZIP4 by RNA Interference Inhibits Pancreatic Cancer Growth and Increases the Survival of Nude Mice with Pancreatic Cancer Xenografts (2009) (89)
- Inhibition of the Hedgehog Pathway Targets the Tumor-Associated Stroma in Pancreatic Cancer (2012) (89)
- ZIP4 Regulates Pancreatic Cancer Cell Growth by Activating IL-6/STAT3 Pathway through Zinc Finger Transcription Factor CREB (2010) (86)
- CCK stimulates mob-1 expression and NF-κB activation via protein kinase C and intracellular Ca2+ (2000) (85)
- Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: Accurate detection of CA19‐9 levels in pancreatic cancer (2008) (84)
- A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth (2013) (83)
- Accurate molecular classification of human cancers based on gene expression using a simple classifier with a pathological tree-based framework. (2003) (79)
- Dominant Negative Rab3D Inhibits Amylase Release from Mouse Pancreatic Acini* (2002) (77)
- CCK independently activates intracellular trypsinogen and NF-kappaB in rat pancreatic acinar cells. (2001) (75)
- Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells. (2006) (74)
- Galectin-3 Mediates Tumor Cell-Stroma Interactions by Activating Pancreatic Stellate Cells to Produce Cytokines via Integrin Signaling. (2017) (73)
- Targeting Pancreatic Ductal Adenocarcinoma Acidic Microenvironment (2014) (70)
- Secretagogues differentially activate endoplasmic reticulum stress responses in pancreatic acinar cells. (2007) (69)
- Intracellular Trypsin Induces Pancreatic Acinar Cell Death but Not NF-κB Activation* (2009) (66)
- Trefoil Factor 1 Stimulates Both Pancreatic Cancer and Stellate Cells and Increases Metastasis (2011) (65)
- Raf kinase inhibitory protein inhibits β-cell proliferation (2004) (62)
- Pancreatic acinar cells in monolayer culture: direct trophic effects of caerulein in vitro. (1986) (59)
- Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models (2011) (59)
- Endoplasmic reticulum stress and the pancreatic acinar cell (2008) (58)
- Regulating Insulin-Receptor-Gene Expression by Differentiation and Hormones (1990) (58)
- The Significance of Ras Activity in Pancreatic Cancer Initiation (2016) (57)
- Progress on molecular markers of pancreatic cancer (2007) (57)
- Robust acinar cell transgene expression of CreErT via BAC recombineering (2008) (57)
- Identification and cloning of GP-3 from rat pancreatic acinar zymogen granules as a glycosylated membrane-associated lipase. (1993) (57)
- Cholecystokinin induction of mob-1 chemokine expression in pancreatic acinar cells requires NF-κB activation. (1999) (56)
- Smad4 mediates activation of mitogen-activated protein kinases by TGF-beta in pancreatic acinar cells. (2001) (55)
- Ras activity in acinar cells links chronic pancreatitis and pancreatic cancer. (2009) (54)
- Transfected cholecystokinin receptors mediate growth inhibitory effects on human pancreatic cancer cell lines. (1997) (52)
- Expression of receptors for cholecystokinin and other Ca2+-mobilizing hormones in Xenopus oocytes. (1988) (51)
- Molecular Profiling of Direct Xenograft Tumors Established from Human Pancreatic Adenocarcinoma After Neoadjuvant Therapy (2012) (51)
- New Blocking Antibodies against Novel AGR2–C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in Mice (2015) (51)
- Regulation of pancreatic acinar cell insulin receptors by insulin. (1984) (48)
- Mutation of carboxyl-terminal threonine residues in human m3 muscarinic acetylcholine receptor modulates the extent of sequestration and desensitization. (1995) (46)
- Dietary Energy Balance Modulation of Kras- and Ink4a/Arf+/−-Driven Pancreatic Cancer: The Role of Insulin-like Growth Factor-I (2013) (46)
- Pancreatic acini in short-term culture: regulation by EGF, carbachol, insulin, and corticosterone. (1983) (46)
- Phenotypic changes in mouse pancreatic stellate cell Ca2+ signaling events following activation in culture and in a disease model of pancreatitis (2011) (45)
- The induction of S100p expression by the Prostaglandin E2 (PGE2)/EP4 receptor signaling pathway in colon cancer cells (2010) (45)
- Functional somatostatin receptors on a rat pancreatic acinar cell line. (1988) (44)
- Prostaglandin E2 Regulates Pancreatic Stellate Cell Activity Via the EP4 Receptor (2013) (44)
- Raf kinase inhibitory protein inhibits beta-cell proliferation. (2004) (44)
- Mechanism of glucocorticoid-induced increase in pancreatic amylase gene transcription. (1987) (43)
- Increased MMP-9 expression and activity by aortic smooth muscle cells after nitric oxide synthase inhibition is associated with increased nuclear factor-kappaB and activator protein-1 activity. (2004) (43)
- CCK stimulates mob-1 expression and NF-kappaB activation via protein kinase C and intracellular Ca(2+). (2000) (41)
- CCK, bombesin, and carbachol stimulate c-fos, c-jun, and c-myc oncogene expression in rat pancreatic acini. (1992) (41)
- Regulation of Insulin-Receptor mRNA Levels by Glucocorticoids (1987) (40)
- Stress-activated protein kinase activation is the earliest direct correlate to the induction of secretagogue-induced pancreatitis in rats. (1996) (39)
- Long-term Ethanol Consumption Alters Pancreatic Gene Expression in Rats: A Possible Connection to Pancreatic Injury (2006) (39)
- Designing and Developing S100P Inhibitor 5-Methyl Cromolyn for Pancreatic Cancer Therapy (2013) (39)
- Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53 (2016) (39)
- Identification of a Specific Vimentin Isoform That Induces an Antibody Response in Pancreatic Cancer (2006) (38)
- TM4SF1 Regulates Pancreatic Cancer Migration and Invasion In Vitro and In Vivo (2016) (37)
- The CUL7/F-box and WD Repeat Domain Containing 8 (CUL7/Fbxw8) Ubiquitin Ligase Promotes Degradation of Hematopoietic Progenitor Kinase 1* (2013) (37)
- Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet. (2019) (37)
- Cholecystokinin stimulates heat shock protein 27 phosphorylation in rat pancreas both in vivo and in vitro. (1997) (37)
- Pancreatic digestive enzyme gene expression: effects of CCK and soybean trypsin inhibitor. (1989) (36)
- Dexamethasone effects on somatostatin receptors in pancreatic acinar AR4-2J cells. (1987) (36)
- The Interface of Pancreatic Cancer With Diabetes, Obesity, and Inflammation: Research Gaps and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. (2018) (36)
- Human pancreatic acinar cells do not respond to cholecystokinin. (2002) (36)
- Improved Retention of Zymogen Granules in Cultured Murine Pancreatic Acinar Cells and Induction of Acinar-Ductal Transdifferentiation In Vitro (2005) (34)
- Regulator of calcineurin 1 controls growth plasticity of adult pancreas. (2010) (34)
- Species Differences between Rat and Mouse CCKAReceptors Determine the Divergent Acinar Cell Response to the Cholecystokinin Analog JMV-180* (2000) (34)
- Intracellular Ca2+ and phorbol esters synergistically inhibit internalization of epidermal growth factor in pancreatic acini. (1984) (33)
- Both low- and high-affinity CCK receptor states mediate trophic effects on rat pancreatic acinar cells. (1993) (33)
- Disruption of TGFβ signaling pathways in human pancreatic cancer cells (2000) (33)
- The ADMR Receptor Mediates the Effects of Adrenomedullin on Pancreatic Cancer Cells and on Cells of the Tumor Microenvironment (2009) (32)
- Molecular Mechanism Underlying Partial and Full Agonism Mediated by the Human Cholecystokinin-1 Receptor* (2005) (32)
- Role of small GTP binding proteins in the growth-promoting and antiapoptotic actions of gastrin. (2004) (32)
- Cholecystokinin induction of mob-1 chemokine expression in pancreatic acinar cells requires NF-kappaB activation. (1999) (32)
- Adenovirus-mediated gene transfer of RasN17 inhibits specific CCK actions on pancreatic acinar cells. (1999) (31)
- Pancreatic acinar cell amylase gene expression: selective effects of adrenalectomy and corticosterone replacement. (1987) (31)
- Do insulin and the insulin like growth factors (IGFs) stimulate growth of the exocrine pancreas? (1987) (31)
- Stimulation of both CCK-A and CCK-B receptors activates MAP kinases in AR42J and receptor-transfected CHO cells. (1997) (31)
- DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters. (2019) (30)
- Pancreatic cancer-associated Cathepsin E as a drug activator. (2013) (30)
- CCK-B receptors produce similar signals but have opposite growth effects in CHO and Swiss 3T3 cells. (1997) (29)
- The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer (2019) (29)
- Met Receptor Tyrosine Kinase Signaling Induces Secretion of the Angiogenic Chemokine Interleukin-8/CXCL8 in Pancreatic Cancer (2012) (28)
- Transforming growth factor-β (TGF-β1) inhibits pancreatic acinar cell growth (1992) (28)
- Proteasome-mediated degradation and functions of hematopoietic progenitor kinase 1 in pancreatic cancer. (2009) (28)
- Plectin-1 Targeted AAV Vector for the Molecular Imaging of Pancreatic Cancer (2013) (27)
- Epidermal growth factor binding and biologic effects on mouse pancreatic acini (1983) (27)
- Molecular imaging of Cathepsin E-positive tumors in mice using a novel protease-activatable fluorescent probe. (2011) (26)
- Regulation of muscarinic acetylcholine receptors in cultured guinea pig pancreatic acini. (1986) (26)
- Stimulation of pancreatic growth by cholecystokinin is mediated by high affinity receptors on rat pancreatic acinar cells. (1993) (26)
- Molecular cloning of a gene encoding the histamine H2 receptor. (1991) (26)
- TM4SF1 Promotes Gemcitabine Resistance of Pancreatic Cancer In Vitro and In Vivo (2015) (26)
- Ca2+ signaling through secretagogue and growth factor receptors on pancreatic AR42J cells (1995) (26)
- Digesting new information about the role of trypsin in pancreatitis. (2011) (26)
- Detection of Pancreatic Carcinomas by Imaging Lactose-Binding Protein Expression in Peritumoral Pancreas Using [18F]Fluoroethyl-Deoxylactose PET/CT (2009) (24)
- Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma (2018) (24)
- Transgenic Expression of PRSS1R122H Sensitizes Mice to Pancreatitis. (2020) (24)
- Human m3 muscarinic acetylcholine receptor carboxyl-terminal threonine resides are required for agonist-induced receptor down-regulation. (1993) (24)
- Carboxyl-terminal Domains Determine Internalization and Recycling Characteristics of Bombesin Receptor Chimeras (*) (1995) (24)
- Bisphosphonates Inhibit Stellate Cell Activity and Enhance Antitumor Effects of Nanoparticle Albumin–Bound Paclitaxel in Pancreatic Ductal Adenocarcinoma (2014) (24)
- Islet hypertrophy following pancreatic disruption of Smad4 signaling. (2006) (23)
- Regulation of epithelial cell growth by ZBP-89 (2002) (23)
- Bombesin binding and biological effects on pancreatic acinar AR42J cells. (1987) (23)
- Adenoviral-mediated gene transfer of a constitutively active retinoblastoma gene inhibits human pancreatic tumor cell proliferation. (1997) (23)
- Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer (2020) (21)
- Influence of Second and Third Cytoplasmic Loops on Binding, Internalization, and Coupling of Chimeric Bombesin/m3 Muscarinic Receptors (*) (1995) (20)
- Induction of inflammatory bowel disease accelerates adenoma formation in Min +/- mice. (2006) (20)
- Animal Models of Gastrointestinal and Liver Diseases. The difficulty of animal modeling of pancreatic cancer for preclinical evaluation of therapeutics. (2015) (20)
- Transforming growth factor-beta (TGF-beta 1) inhibits pancreatic acinar cell growth. (1992) (20)
- Lysophosphatidic acid stimulates calcium transients in enteric glia (2004) (20)
- Muscarinic acetylcholine receptor down-regulation limits the extent of inhibition of cell cycle progression in Chinese hamster ovary cells. (1995) (20)
- Adenovirus-mediated gene transfer of dominant-negative Smad4 blocks TGF-β signaling in pancreatic acinar cells (2001) (19)
- Effect of intracellular Ca2+ on insulin-like growth factor II. internalization into pancreatic acini. Roles of insulin and cholecystokinin. (1984) (18)
- Glandular kallikrein gene expression is selectively down-regulated by glucocorticoids in pancreatic AR42J cells. (1991) (18)
- Sphingosine-1-phosphate mediates calcium signaling in guinea pig enteroglial cells. (2004) (18)
- Disruption of TGFbeta signaling pathways in human pancreatic cancer cells. (2000) (18)
- Direct trophic effects of fibroblast growth factors on rat pancreatic acinar cells in vitro. (1993) (18)
- RAGE maintains high levels of NFκB and oncogenic Kras activity in pancreatic cancer. (2017) (18)
- Obesogenic high-fat diet heightens aerobic glycolysis through hyperactivation of oncogenic KRAS (2019) (18)
- Pancreatic duct cell cultures: there is more to ducts than salty water. (1995) (17)
- Direct versus indirect action of cholecystokinin on human pancreatic acinar cells: is it time for a judgment after a century of trial? (2008) (16)
- Bovine chromaffin granule membranes undergo Ca(2+)-regulated exocytosis in frog oocytes (1992) (15)
- Study human pancreatic cancer in mice: how close are they? (2013) (15)
- Glucocorticoids stimulate ornithine decarboxylase gene expression in pancreatic AR42J cells. (1991) (15)
- Epidermal growth factor: intracellular Ca2+ inhibits its association with pancreatic acini and A431 cells (1983) (15)
- Monoclonal antibodies as probes for plasma membrane domains in the exocrine pancreas. (1988) (13)
- Role of Cholecystokinin in Physiologic and Pathophysiologic Growth of the Pancreas (1999) (13)
- Involvement of extracellular calcium in gastric stimulation. (1981) (13)
- A prospective study of soluble receptor for advanced glycation end-products and colorectal cancer risk in postmenopausal women. (2016) (12)
- Isolation and monolayer culture of guinea pig pancreatic duct epithelial cells (1988) (12)
- Synthesis and Ex Vivo Autoradiographic Evaluation of Ethyl-β-d-galactopyranosyl-(1,4′)-2′-deoxy-2′-[18F]fluoro-β-d-glucopyranoside—A Novel Radioligand for Lactose-Binding Protein: Implications for Early Detection of Pancreatic Carcinomas with PET (2011) (12)
- Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype (2015) (12)
- Effects of calcium mediated secretagogues on the growth of pancreatic acinar cells in vitro. (1987) (12)
- Pancreatic kallikrein gene expression: effects of glucocorticoids in vivo and in vitro. (1989) (11)
- The influence of the cellular context on receptor function: a necessary consideration for physiologic interpretations of receptor expression studies. (1999) (11)
- Epidermal growth factor binding and biologic effects on mouse pancreatic acini. (1983) (11)
- Convergence of Nanotechnology and Cancer Prevention: Are We There Yet? (2014) (10)
- Effects of cholecystokinin on pancreatic ornithine decarboxylase gene expression. (1988) (10)
- Ultrastructural changes during stimulation of amphibian oxyntic cells viewed by scanning and transmission electron microscopy (1982) (10)
- Effects of bombesin on pancreatic digestive enzyme gene expression. (1992) (9)
- Chemoprevention of Pancreatic Cancer: Ready for the Clinic? (2010) (9)
- Phosphatidylinositol 3-kinase and trypsin activation in pancreatitis. (2001) (8)
- Cancer Metabolism and Its Therapeutic Implications (2013) (8)
- Adenovirus-mediated gene transfer of dominant-negative Smad4 blocks TGF-beta signaling in pancreatic acinar cells. (2001) (8)
- Novel Kinase Signaling Cascades in Pancreatic Acinar Cells (1997) (7)
- Chinese hamster ovary mRNA-dependent, Na(+)-independent L-leucine transport in Xenopus laevis oocytes (1992) (7)
- Hematopoietic progenitor kinase 1 down-regulates the oncogenic receptor tyrosine kinase AXL in pancreatic cancer (2020) (7)
- Signal transduction in pancreatic acinar cell physiology and pathophysiology. (2000) (7)
- Sphingosine-1-phosphate induces early response gene expression in C6 glioma cells. (2005) (7)
- Downregulation of GSTM2 enhances gemcitabine chemosensitivity of pancreatic cancer in vitro and in vivo. (2020) (6)
- Ionic requirements for H+ secretion and membrane elaboration in frog oxyntic cells. (1982) (6)
- Role of polyamines in glucocorticoid effects on pancreatic acinar AR42J cell growth and differentiation. (1992) (6)
- High-Affinity and Low-Affinity CCKA Receptor States Mediate Specific Growth-Inhibitory Effects on CHO Cells (1995) (6)
- Smad 4 mediates activation of mitogen-activated protein kinases by TGF-b in pancreatic acinar cells (2001) (6)
- Fetal rabbit gastric epithelial cells cultured on floating collagen gels (1982) (5)
- Down-regulation of the G-proteins Gq alpha and G11 alpha by transfected human M3 muscarinic acetylcholine receptors in Chinese hamster ovary cells is independent of receptor down-regulation. (1995) (5)
- Bovine chromaffin granule membranes undergo Ca2+-regulated exocytosis in frog oocytes: J. Cell Biol. 116, 359–365 (1992) (4)
- Nucleotides regulate the binding affinity of the recombinant type A cholecystokinin receptor in CHO K1 cells (1996) (4)
- Glucocorticoids have opposite effects on ornithine decarboxylase and cell growth in pancreatic acinar AR42J cells. (1992) (4)
- Recent Advancements in Pancreatic Cancer Immunotherapy (2016) (4)
- Acinar Ductal Metaplasia: Yap Fills a Gap. (2016) (4)
- The RAGE ligand, S100P, has increased expression in colon cancer (2004) (3)
- Pancreatic Cancer Growth , Survival , and Invasion (2005) (3)
- CCK-B receptors produce similar signals but have opposite growth effects in CHO and Swiss 3T3 cells. (1997) (3)
- Adenovirus-mediated gene transfer of RasN 17 inhibits specific CCK actions on pancreatic acinar cells (1999) (3)
- Expression of Ca2+ mobilizing receptors in Xenopus oocytes: a tool for receptor characterization. (1990) (3)
- Transgenic expression of cyclooxygenase-2 in pancreatic acinar cells induces chronic pancreatitis. (2019) (3)
- Oligonucleotide-directed microarray gene profiling of pancreatic adenocarcinoma. (2005) (2)
- Oncogenic Ras requires activation for pathological levels of activity (2013) (2)
- 19 – Pancreatic Adaptation Involves Regulation of Gene Expression by Cholecystokinin (1990) (2)
- Elevated acinar cell NF-κB activity increases pancreatitis severity (2013) (2)
- Differential Effects of Dietary Macronutrients on the Development of Oncogenic KRAS-Mediated Pancreatic Ductal Adenocarcinoma (2022) (2)
- High- and low-affinity CCKA receptor states mediate specific growth inhibitory effects on CHO cells. (1995) (2)
- Nuclear factor-K B maintains TRAIL resistance in human pancreatic cancer cells (2006) (2)
- PGE2 Regulates Pancreatic Stellate Cell Activity Via The EP4 Receptor (2013) (2)
- Independent activation of trypsinogen and NFKB in pancreatic acinar cells during experimental acute pancreatitis (2000) (1)
- Lipocalin-2 Promotes Obesity-Induced Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment (2016) (1)
- The ataxia telangiectasia group D associated gene confers a cellular survival advantage in pancreatic adenocarcinoma (2003) (1)
- Molecular Relationships Between Chronic Pancreatitis and Cancer (2010) (1)
- EXPRESSION OF CELL DIVISION CYCLE 20 HOMOLOG (CDC20) IS ASSOCIATED WITH TUMORIGENESIS AND PROGRESSION OF PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) (2008) (1)
- Mutant Human PRSS1 R122H Expression in Mice Greatly Exacerbates Pancreatitis (2017) (1)
- Correlation between the stimulation of c-fos gene expression and DNA synthesis in rat pancreatic acinar cells in vitro (1995) (1)
- Molecular and Cellular Pathobiology A Novel FoxM 1-Caveolin Signaling Pathway Promotes Pancreatic Cancer Invasion and Metastasis (2012) (1)
- Long‐Term Regulation of Pancreatic Function Studied in Vitro (2011) (1)
- ADRENOMEDULLIN IS OVEREXPRESSED IN PANCREATIC CANCER AND STIMULATES CELL GROWTH AND INVASION. (2004) (1)
- Abstract 891: FGF21 prevents high fat diet-induced pancreatic cancer in mice expressing oncogenic Kras (2015) (1)
- CROMOLYN BLOCKS S100P ACTIVATION OF RAGE AND IMPROVES GEMCITABINE EFFECTIVENESS IN PANCREATIC CANCER (2006) (1)
- gene transfer of a constitutively active retinoblastoma gene inhibits human pancreatic tumor ceil proliferation (1997) (1)
- DEVELOPMENT OF AN EFFICIENT INDUCIBLE ACINAR CELL SPECIFIC TRANSGENIC MODEL (2006) (1)
- The MET Receptor Tyrosine Kinase Confers Repair of Murine Pancreatic Acinar Cells following Acute and Chronic Injury (2016) (1)
- Abstract 2357: Novel transgenic animal model of salivary gland tumors (2012) (1)
- Abstract LB-187: Dietary energy balance modulation of Kras- and Ink4a/Arf+/-driven pancreatic cancer: the role of insulin-like growth factor-1. (2013) (1)
- Abstract LB-425: An NF-κB pathway mediated positive feedback loop amplifies Ras activity to pathological levels in mice (2012) (1)
- TUMOR-ASSOCIATED PANCREATIC STELLATE CELLS STIMULATE ANGIOGENESIS IN VITRO AND IN AN ORTHOTOPIC MODEL OF PANCREATIC CANCER (2008) (1)
- S100P INCREASES PANCREATIC CANCER GROWTH AND INVASION. (2004) (1)
- Identification of pancreatic genes expressed during the initiation of acute pancreatitis: EGR-1 is a key regulator (2003) (1)
- M1970 Knock Down of Signal Tranducer and Avtivator of Transcripton3 (STAT3) Enhance Gemcitabine Mediated Apoptosis in Chemoresistant Pancreatic Cancer Cells In Vitro and In Vivo (2010) (0)
- 132 Galectin-3 Induces Human Pancreatic Stellate Cell Activation and IL-8 Production via NF-kB Signaling (2010) (0)
- Minutes of the Business Meeting of the American Pancreatic Association, Friday, November 6, 2009, Honolulu, Hawaii (2010) (0)
- GENE EXPRESSION PROFILING DISTINGUISHES BETWEEN DRUG-SENSITIVE AND RESISTANT PANCREATIC CANCER CELL LINES (2008) (0)
- Evaluation of 1'-[18F]fluoroethyl-{beta}-D-lactose ([18F]FEL) for detection of pancreatic cancer in nude mouse orthotopic xenografts (2014) (0)
- Regulated in Pancreatic Cancer Chronic Pancreatitis Identifies Multiple Genes Differentially Molecular Profiling of Pancreatic Adenocarcinoma and Updated (2003) (0)
- DIETARY ZINC TRANSPORTER ZIP4 IS A MALIGNANT FACTOR AND THERAPEUTIC TARGET IN PANCREATIC CANCER (2008) (0)
- Abstract PR6: Oncogenic Ras requires stimulation for activity sufficient to initiate a feed-forward inflammatory mechanism capable of inducing pancreatic diseases, including pancreatitis and cancer. (2012) (0)
- ADRENOMEDULLIN IS AN AUTOCRINE REGULATOR OF PANCREATIC CANCER ACTING VIA THE ADMR RECEPTOR (2006) (0)
- 475q Tm4sf1 is Highly Expressed in Pancreatic Cancer and Promotes Cancer Cell Migration, Invasion and Survival (2010) (0)
- Abstract 3920: EphA2 transcription is regulated by activation of Ras / MEK2 / cytoplasmic ERK pathway in pancreatic cancer (2010) (0)
- Adenovirus-mediated gene transfer of dominant-negative Smad4 blocks TGF- b signaling in pancreatic acinar cells (2001) (0)
- Mechanisms of pancreatic cancer associated with obesity or dietary fat (2015) (0)
- TGFβ activation of cAMP responsive element-binding protein (CREB) is dependent on PKA and smads in pancreatic acinar cells (2001) (0)
- Genes down-regulated in pancreatic adenocarcinoma affect cell survival: Reintroduction of proapoptotic BNIP3 leads to cancer cell death (2003) (0)
- ASIC — LIVER , PANCREAS , AND BILIARY RACT as Activity Levels Control the Development of Pancreatic Diseases (0)
- Abstract B24: Targeting pancreatic ductal adenocarcinoma acidic microenvironment (2015) (0)
- Abstract #LB-148: Mast cells in the tumor microenvironment are essential for the tumorigenesis of pancreatic ductal adenocarcinoma (PDAC) (2009) (0)
- Transforming growth factor β activates mitogen-activated (MAP) kinases in pancreatic acinar cells (1998) (0)
- Adenovirus-mediated gene transfer of RasN17 inhibits specific CCK actions on pancreatic acinar cells. (1999) (0)
- Abstract 4328: Galectin-3 mediates tumor-stromal interaction by activating pancreatic stellate cell through integrinβ1/ILK/NF-κB signaling (2017) (0)
- Targeting Periostin in the Tumor-Associated Stroma of Pancreatic Cancer (2010) (0)
- Abstract 4437: Fbxw8 targets hematopoietic progenitor kinase 1 for proteasomal degradation (2014) (0)
- TGFb inhibits growth in a human pancreatic cancer cell line lacking DPC4 (2000) (0)
- PANCREATIC GENE EXPRESSION DURING ARGININE-INDUCED PANCREATITIS (2006) (0)
- ADRENOMEDULLIN ACTIVATES PANCREATIC TUMOR, STELLATE AND ENDOTHELIAL CELLS VIA THE ADMR RECEPTOR (2008) (0)
- B-cyclodextrins enhance efficiency of adenoviral mediated gene delivery to pancreas in vivo without inducing pancreatitis (2000) (0)
- Abstract C61: High fat triggers oncogenic K-Ras activity and a COX2 dependent feed-forward loop to induce pancreatic ductal adenocarcinoma development (2013) (0)
- 890 Intracellular Trypsinogen Activation Induces Pancreatic Acinar Cell Apoptosis and Necrosis While Extracellular Trypsin Activates Nf-κB (2008) (0)
- Systemic Delivery of Liposome-Incorporated Adrenomedullin Receptor (ADMR) Small Interfering RNA Against Tumor and Its Microenvironment Reduced Pancreatic Tumor Growth (2009) (0)
- CROSS-PLATFORM MOLECULAR PROFILING OF CELLULAR PATHWAYS INVOLVED IN PANCREATIC CANCER (2007) (0)
- Retraction Statement: Paper by Qian Y, Ma J, Guo X, Sun J, Yu Y, CaoB, Zhang L, Ding X, Huang J, Shao JF, entitled ‘Curcumin Enhances the Radiosensitivity ofU87 Cells by Inducing DUSP-2 Up-Regulation‘ Cell Physiol Biochem 2015;35(4):1381-93.doi: 10.1159/000373959 (2016) (0)
- LIPOSOMAL DELIVERY OF EPHA2 SIRNA IN COMBINATION WITH GEMCITABINE REDUCES PANCREATIC TUMOR GROWTH AND INVASION (2006) (0)
- EXTRACELLULAR BUT NOT INTRACELLULAR TRYPSIN ACTIVATES NF-KAPPA B. (2004) (0)
- A TGFβ-INDUCED SMAD3/SMAD4 COMPLEX DIRECTLY ACTIVATES PROTEIN KINASE A: THE INTERACTION DOMAINS OF THE TRIMERIC COMPLEX. (2004) (0)
- Abstract 937: Soluble receptor for advanced glycation end-products is a player in obesity-related colorectal cancer (2015) (0)
- Abstract A112: Eradication of cancer stem-like cells in PDAC (2015) (0)
- CCKB/gastrin receptors expressed in mouse pancreatic acinar cells couple to similar responses as CCKA receptors at physiologic agonist concentrations but show differences at high concentrations (2000) (0)
- SECRETAGOGUES DIFFERENTIALLY ACTIVATE ENDOPLASMIC RETICULUM STRESS RESPONSES IN PANCREATIC ACINI (2007) (0)
- M1961 Galectin-3 Induces Cell Proliferation and Invasion by Binding K-RAS and Activating RAS Signaling in Pancreatic Cancer Cells (2010) (0)
- Correction to: Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer (2021) (0)
- Effects of oncogenic K-ras on pancreatic acinar cells In vitro (2001) (0)
- SILENCING OF STAT3 ENHANCES GEMCITABINE MEDIATED APOPTOSIS IN CHEMORESISTANT PANCREATIC CANCER CELLS (2008) (0)
- A High-Fat Diet Activates Oncogenic Kras and COX 2 to Induce Development of Pancreatic Ductal Adenocarcinoma in Mice Short Title : Mechanism of high fat diet induction of PDAC (2013) (0)
- Ca2+ and phorbol esters synergistically inhibit the internalization of EGF and IGF II (1984) (0)
- Abstract 1094: Dynamics of Gemcitabine induced interleukin-8 (IL-8) expression in pancreatic tumor microenvironment (2014) (0)
- ARGININE PANCREATITIS INDUCES ENDOPLASMIC RETICULUM STRESS. (2004) (0)
- Small Molecule Therapeutics Bisphosphonates Inhibit Stellate Cell Activity and Enhance Antitumor Effects of Nanoparticle Albumin – Bound Paclitaxel in Pancreatic Ductal Adenocarcinoma (2014) (0)
- Abstract 5075: Naproxen blocks spontaneous lung adenoma progression to adenocarcinoma in Kras-G12Vmice (2019) (0)
- Hedgehog signaling in pancreatic cancer is dependent on stellate cells in a paracrine fashion (2013) (0)
- ANTERIOR GRADIENT-2 IS OVER-EXPRESSED IN PANCREATIC CANCER AND ITS SILENCING REDUCED CELL GROWTH, MIGRATION, INVASION AND SURVIVAL (2005) (0)
- Minutes of the Business Meeting of the American Pancreatic Association Thursday, November 6, 2008, Chicago, Illinois (2009) (0)
- Abstract LB-504: Mast cell cytokines stimulate cancer-associated fibroblasts proliferation and promote pancreatic cancer progression (2012) (0)
- Minutes of the Business Meeting of the American Pancreatic Association Friday, November 4, 2005, Chicago, Illinois (2006) (0)
- Abstract 2961: Targeting stromal-derived Dickkopf-3 (DKK3) for the treatment of pancreatic ductal adenocarcinoma (PDAC) (2017) (0)
- ACINAR CELL SPECIFIC TARGETING OF MUTANT KRAS INDUCES CHRONIC PANCREATITIS, PREINVASIVE, INVASIVE, AND METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA (2007) (0)
- Subject Index, Vol. 46, Supplement 2, 1990 (1990) (0)
- Lysophosphatidic acid signaling in the enteric nervous system (2001) (0)
- TRANSGENIC EXPRESSION OF ACTIVATED K-RAS IN PANCREATIC ACINAR CELLS CAUSES PANCREATIC DAMAGE RESEMBLING CHRONIC PANCREATITIS (2006) (0)
- 70. Targeting Zinc Transporter ZIP4 Inhibits Pancreatic Cancer Progession (2009) (0)
- TRANSGENIC EXPRESSION OF THE NFκB SUBUNIT p65 IN PANCREATIC ACINAR CELLS OF TRANSGENIC MICE INCREASES THE SEVERITY OF ACUTE PANCREATITIS (2005) (0)
- CEACAM1 IS A BIOMARKER FOR PANCREATIC CANCER. (2004) (0)
- Abstract B51: Gemcitabine-induced interleukin-8 expression is a surrogate marker for effects on pancreatic ductal adenocarcinoma cells and is associated with tumor microenvironment remodeling. (2012) (0)
- PANCREATIC CANCER ASSOCIATED GENE EXPRESSION FROM FNA SAMPLES DIFFERENTIATES NEOPLASTIC FROM BENIGN PANCREATIC DISEASES. (2004) (0)
- CCKA receptor structural differences determine the acinar cell response to the CCK analog JMV-180 in rat and mouse (2000) (0)
- Pancreatic Enzyme Secretion (Physiology) (2004) (0)
- S100P is expressed in pancreatic adenocarcinoma and stimulates pancreatic cancer cell proliferation and survival (2003) (0)
- Minutes of the Business Meeting of the American Pancreatic Association Thursday, November 2, 2006, Chicago, Illinois (2007) (0)
- Abstract 4959: Targeting pancreatic stellate cells (PSC) to treat pancreatic cancer. (2013) (0)
- Cck bombesin and carbachol stimulate oncogene expression in rat pancreatic acini (1990) (0)
- CCKA receptor activation inhibits CHO cell growth via both high and low affinity states (1995) (0)
- A REVERSE PHASE ARRAY PLATFORM FOR MEASUREMENT OF PANCREATIC BIOMARKERS (2006) (0)
- NFkB reporter signaling distinguishes gemcitabine sensitive from resistant cell lines (2007) (0)
- Effects of CCK on gene expression of endocrine pancreatic hormones. (1990) (0)
- Transcription factor activation by TGFB in pancreatic acinar cells: role of DPC4 and map kinases (2000) (0)
- Abstract 4711: Novel mechanism involved in the regulation ofoncogenic Axl receptor tyrosine kinase in cancer (2020) (0)
- Acknowledgement to Reviewers (2012) (0)
- Abstract B113: High Fat Diet Accelerates Development of Precancerous Lesions and Fibrosis in Mice Expressing mutant K-Ras in Pancreatic Acinar Cells (2012) (0)
- TFF1 is expressed early in pancreatic cancer and increases cancer cell invasion and growth and migration of stellate cells within the tumor microenvironment. (2008) (0)
- INTRACELLULAR TRYPSINOGEN ACTIVATION INDUCES APOPTOSIS. (2004) (0)
- Abstract 3822: Immunosuppressive role of mast cells is essential for the tumorigenesis of pancreatic ductal adenocarcinoma (PDAC) (2010) (0)
- YAP PART OF THE HIPPO PATHWAY IS OVEREXPRESSED IN PANCREATIC CANCER (2007) (0)
- Acknowledgement to Referees (1998) (0)
- Molecular Markers From EUS Fine Needle Specimens Can Differentiate Pancreatic Neoplasia Requiring Surgery From Chronic Pancreatitis and Other Benign Conditions of the Pancreas (2005) (0)
- Abstract 1837: High Ras activity promotes neoplasia in pancreatic ductal cells (2017) (0)
- Pancreatic cancer cells do not express functional levels of CCK1 or CCK2 receptor mRNA (2003) (0)
- M2023 Expression of Cathepsin E Reverses EMT in Pancreatic Cancer Cells In Vitro and Expression Correlates with Increased Patient Survival in Human Pancreatic Adenocarcinoma (2008) (0)
- Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer. (2021) (0)
- ABSTRACTS Session 2: Pancreatic Cancer Mast cells in tumor microenvironment promotes the in vivo growth of pancreatic ductal adenocarcinoma. (2012) (0)
- Autocrine regulation of adrenomedullin on pancreatic cancer cells is mediated via ADMR (2007) (0)
- Acute pancreatitis and systemic inflammatory response induced by NF-κB activation in pancreas (2001) (0)
- PANCREATIC CANCER CELLS HAVE REDUCED RESPONSES TO ER STRESS (2008) (0)
- Obesogenic high-fat diet heightens aerobic glycolysis through hyperactivation of oncogenic KRAS (2019) (0)
- ATDC IS OVEREXPRESSED IN PANCREATIC CANCER AND MAY FUNCTION AS A NOVEL DNA REPAIR GENE (2005) (0)
- SILENCING OF RELA/P65 ENHANCES TRAIL BUT NOT GEMCITABINE MEDIATED APOPTOSIS IN PANCREATIC CANCER CELLS (2006) (0)
- Abstract 3655: Mast cells promote immunosuppression and pancreatic ductal adenocarcinoma development (2011) (0)
- RAGE IS ALTERNATIVELY SPLICED IN PANCREATIC CANCER AND ITS SECRETORY FORM STIMULATES CANCER CELL GROWTH AND INVASION (2005) (0)
- Novel fluorescent probe for selective imaging of Cathepsin E expression in human pancreatic tumors (2011) (0)
- Abstract 806: Selective killing of cancer cells with mitochondrial respiratory dysfunction induced by activation of oncogenic Ras (2014) (0)
- TGFB-mediated growth inhibition and induction of P21 in pancreatic acinar cells is blocked by adenoviral gene transfer of dominant negative DPC4 (2000) (0)
- INHIBITION OF NADPH OXIDASE REDUCES ENDOPLASMIC RETICULUM STRESS AND AMELIORATES ACUTE PANCREATITIS (2005) (0)
- Abstract 5324: Cathepsin E expression: A new potential target for pancreatic tumor imaging (2011) (0)
- CCK increases chemokine gene expression and NFκB activation in rat pancreatic acinar cells in vitro (1998) (0)
- Interleukin-8 (IL-8) expression is a surrogate marker for effects of gemcitabine on pancreatic ductal adenocarcinoma (PDAC) cells (2013) (0)
- Minutes of the Business Meeting of the American Pancreatic Association Friday, November 2, 2007, Chicago, Illinois (2008) (0)
- Adenovirus-mediated gene transfer of dominant negative rasasn17 in pancreatic acinar cells inhibits specific CCK actions (1998) (0)
- Gene expression analysis reveals the complexity of acute pancreatitis (2008) (0)
- 536 Oncogenic Ki-RAS-miR-21 Signaling Promotes AKT Activation in Pancreatic Cancer Cells Through a Novel AKT-Interacting Protein Bsta (2013) (0)
- The Difficulty of Animal Modeling of Pancreatic Cancer for (2015) (0)
- IDENTIFICATION OF A NEW TUMOR SUPPRESSOR GENE RAP1GAP IN PANCREATIC CANCER. (2004) (0)
- THE EVOLVING INFLAMMATORY STATUS IN A TRANSGENETIC SPONTANOUS PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) MOUSE MODEL (2008) (0)
- M1837 Increased Severity of Arginine Induced Pancreatitis Is Reflected By Differential Pancreatic Gene Expression (2008) (0)
- Cerulein-treated Ras-activated mice develop painful chronic pancreatitis (2012) (0)
- Cromolyn blocks S100P activation of RAGE, reduces pancreatic cancer growth and invasion and enhances gemcitabine chemotherapy (2006) (0)
- TRANSGENIC EXPRESSION OF INTRACELLULAR ACTIVE TRYPSIN DOES NOT CAUSE ACUTE PANCREATITIS (2008) (0)
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