Csaba Szabo
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Why Is Csaba Szabo Influential?
(Suggest an Edit or Addition)According to Wikipedia, Csaba Szabo, a physician and pharmacologist, is the Head of the Pharmacology Section of the University of Fribourg in Switzerland. The Public Library of Science Magazine, PLOS Biology, recognized Szabo in 2019 as one of the most cited researchers in the world.
Csaba Szabo 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Peroxynitrite: biochemistry, pathophysiology and development of therapeutics (2007) (1748)
- Hydrogen sulphide and its therapeutic potential (2007) (1622)
- The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors (2002) (1391)
- Therapeutic Effects of Xanthine Oxidase Inhibitors: Renaissance Half a Century after the Discovery of Allopurinol (2006) (1076)
- Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function (2007) (1010)
- Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors (2005) (869)
- Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. (2003) (763)
- Hydrogen sulfide is an endogenous stimulator of angiogenesis (2009) (725)
- Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion. (1998) (701)
- DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite. (1996) (644)
- Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation (2001) (618)
- Selective pharmacological inhibition of distinct nitric oxide synthase isoforms. (1996) (584)
- Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. (1996) (544)
- Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation (2012) (535)
- Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer (2013) (530)
- Multiple pathways of peroxynitrite cytotoxicity. (2003) (508)
- THE PATHOPHYSIOLOGICAL ROLE OF PEROXYNITRITE IN SHOCK, INFLAMMATION, AND ISCHEMIA‐REPERFUSION INJURY (1996) (483)
- DNA damage induced by peroxynitrite: subsequent biological effects. (1997) (443)
- Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention. (2003) (441)
- Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase. (1994) (424)
- Nitric oxide‐mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock (1993) (415)
- Gasotransmitters in cancer: from pathophysiology to experimental therapy (2015) (367)
- Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide. (1993) (361)
- Alterations in nitric oxide production in various forms of circulatory shock. (1995) (355)
- Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease. (2008) (354)
- Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury. (1998) (353)
- Biology of nitric oxide signaling (2000) (339)
- Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro. (2007) (335)
- Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms (2014) (334)
- Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. (1997) (333)
- Therapeutic applications of PARP inhibitors: anticancer therapy and beyond. (2013) (330)
- Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies. (2005) (326)
- Melatonin is a scavenger of peroxynitrite. (1997) (322)
- Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10. (1999) (321)
- Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide. (1996) (318)
- Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE) (2013) (317)
- Effects of nitric oxide in septic shock. (2000) (313)
- Inosine Inhibits Inflammatory Cytokine Production by a Posttranscriptional Mechanism and Protects Against Endotoxin-Induced Shock1 (2000) (304)
- Intra-mitochondrial Poly(ADP-ribosylation) Contributes to NAD+ Depletion and Cell Death Induced by Oxidative Stress* (2003) (300)
- The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes. (2002) (296)
- Physiological and pathophysiological roles of nitric oxide in the central nervous system (1996) (295)
- Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors. (2007) (294)
- Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury. (2000) (292)
- Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity (1995) (288)
- Inhibition of poly (ADP-ribose) Synthetase Attenuates Neutrophil Recruitment and Exerts Antiinflammatory Effects (1997) (283)
- Potent Metalloporphyrin Peroxynitrite Decomposition Catalyst Protects Against the Development of Doxorubicin-Induced Cardiac Dysfunction (2003) (278)
- Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase. (1998) (274)
- Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function (2011) (272)
- MD-2 is required for disulfide HMGB1–dependent TLR4 signaling (2015) (267)
- Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NFκB activation (1998) (264)
- DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite. (1996) (260)
- Immunomodulatory and neuroprotective effects of inosine. (2004) (259)
- Protective effect of melatonin in carrageenan‐induced models of local inflammation: Relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity (1997) (256)
- Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite. (1996) (256)
- Intranuclear localization of apoptosis‐inducing factor (AIF) and large scale dna fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite (2002) (255)
- International Union of Basic and Clinical Pharmacology. CII: Pharmacological Modulation of H2S Levels: H2S Donors and H2S Biosynthesis Inhibitors (2017) (246)
- Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke. (2001) (245)
- Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo (1995) (243)
- Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death. (1998) (242)
- Nitric Oxide Sensitivity of the Aconitases* (1997) (241)
- Intramitochondrial hydrogen sulfide production by 3‐mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics (2013) (241)
- Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase. (1997) (237)
- Nitrosative stress and pharmacological modulation of heart failure. (2005) (231)
- Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation. (1998) (231)
- Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger (1996) (230)
- Peroxynitrite‐induced thymocyte apoptosis: the role of caspases and poly (ADP‐ribose) synthetase (PARS) activation (1998) (226)
- Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock (1995) (225)
- The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock (1997) (218)
- Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy. (2004) (215)
- Poly(ADP-Ribose) Polymerase Is Involved in the Development of Diabetic Retinopathy via Regulation of Nuclear Factor-κB (2004) (215)
- Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo. (1994) (214)
- Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase. (2000) (212)
- Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects (2014) (211)
- Reactive oxygen species mediate a cellular ‘memory’ of high glucose stress signalling (2007) (205)
- AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro. (2014) (204)
- A monobromobimane‐based assay to measure the pharmacokinetic profile of reactive sulphide species in blood (2010) (203)
- Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock (1993) (202)
- Novel phenanthridinone inhibitors of poly(adenosine 5′-diphosphate-ribose) synthetase: Potent cytoprotective and antishock agents* (2002) (198)
- Activation of poly(ADP-Ribose) polymerase-1 is a central mechanism of lipopolysaccharide-induced acute lung inflammation. (2002) (195)
- Poly(ADP-ribose) polymerase inhibitors. (2003) (193)
- Toxicological and pathophysiological roles of reactive oxygen and nitrogen species. (2010) (189)
- Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure. (2002) (188)
- Intermittent high glucose enhances ICAM‐1, VCAM‐1, E‐selectin and interleukin‐6 expression in human umbilical endothelial cells in culture: the role of poly(ADP‐ribose) polymerase (2004) (187)
- Suppression of macrophage inflammatory protein (MIP)‐1α production and collagen‐induced arthritis by adenosine receptor agonists (1998) (187)
- INVITED OPINION: ROLE OF NITRIC OXIDE IN HEMORRHAGIC, TRAUMATIC, AND ANAPHYLACTIC SHOCK AND THERMAL INJURY (1994) (186)
- Part I: Pathogenetic Role of Peroxynitrite in the Development of Diabetes and Diabetic Vascular Complications: Studies With FP15, A Novel Potent Peroxynitrite Decomposition Catalyst (2002) (178)
- Hydrogen sulphide and angiogenesis: mechanisms and applications (2011) (177)
- Roles of hydrogen sulfide in the pathogenesis of diabetes mellitus and its complications. (2012) (176)
- Beneficial effects of 3‐aminobenzamide, an inhibitor of poly (ADP‐ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion (1997) (175)
- Mercaptoethylguanidine and Guanidine Inhibitors of Nitric-oxide Synthase React with Peroxynitrite and Protect against Peroxynitrite-induced Oxidative Damage* (1997) (175)
- Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications. (2005) (174)
- Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair–deficient malignant glioma xenograft (2005) (173)
- The effects of therapeutic sulfide on myocardial apoptosis in response to ischemia-reperfusion injury. (2008) (171)
- Poly(ADP-Ribose) Polymerase Is Activated in Subjects at Risk of Developing Type 2 Diabetes and Is Associated With Impaired Vascular Reactivity (2002) (170)
- The therapeutic potential of cystathionine β-synthetase/hydrogen sulfide inhibition in cancer. (2015) (170)
- Role of peroxynitrite in the pathogenesis of cardiovascular complications of diabetes. (2006) (169)
- Poly(ADP-ribose) polymerase inhibition: past, present and future (2020) (167)
- Resistance to Acute Septic Peritonitis in Poly(ADP-ribose) Polymerase-1-Deficient Mice (2002) (166)
- Bench-to-bedside review: Hydrogen sulfide – the third gaseous transmitter: applications for critical care (2009) (164)
- Peroxynitrite‐mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia‐reperfusion injury (1995) (162)
- Poly(ADP-Ribose) Polymerase Inhibition Reduces Reperfusion Injury After Heart Transplantation (2002) (160)
- BENEFICIAL VERSUS DETRIMENTAL EFFECTS OF NITRIC OXIDE SYNTHASE INHIBITORS IN CIRCULATORY SHOCK LESSONS LEARNED FROM EXPERIMENTAL AND CLINICAL STUDIES (1997) (159)
- Rapid Reversal of the Diabetic Endothelial Dysfunction by Pharmacological Inhibition of Poly(ADP-Ribose) Polymerase (2001) (158)
- Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme. (2005) (158)
- Clinical perspectives of PARP inhibitors. (2005) (155)
- Regulation of cytokine and chemokine production by transmitters and co-transmitters of the autonomic nervous system. (1998) (155)
- Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst (2005) (153)
- A timeline of hydrogen sulfide (H2S) research: From environmental toxin to biological mediator. (2017) (151)
- Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide. (1993) (150)
- Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction (2009) (148)
- An agonist of adenosine A3 receptors decreases interleukin-12 and interferon-gamma production and prevents lethality in endotoxemic mice. (1998) (148)
- Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase (1999) (147)
- Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury. (2009) (145)
- Opportunities for the repurposing of PARP inhibitors for the therapy of non‐oncological diseases (2018) (145)
- Mitochondrial nitric oxide synthase is not eNOS, nNOS or iNOS. (2003) (144)
- Vascular biology of hydrogen sulfide. (2017) (142)
- Hydrogen Sulfide and Cancer. (2015) (141)
- Isoproterenol regulates tumour necrosis factor, interleukin‐10, interleukin‐6 and nitric oxide production and protects against the development of vascular hyporeactivity in endotoxaemia (1997) (138)
- Novel roles of nitric oxide in hemorrhagic shock. (1999) (137)
- Role of nitric oxide in vascular permeability after combined burns and smoke inhalation injury. (2001) (134)
- Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase (2001) (133)
- Induction and activity of nitric oxide synthase in cultured human intestinal epithelial monolayers. (1996) (130)
- S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics. (2016) (129)
- Left ventricular pressure-volume relationship in a rat model of advanced aging-associated heart failure. (2004) (128)
- Effects of NG‐nitro‐L‐arginine and L‐arginine on regional cerebral blood flow in the cat. (1992) (126)
- Hydrogen sulfide, an enhancer of vascular nitric oxide signaling: mechanisms and implications. (2017) (125)
- Cardioprotective effects of hydrogen sulfide. (2011) (124)
- Poly(ADP-Ribose) Polymerase Inhibitors Ameliorate Nephropathy of Type 2 Diabetic Leprdb/db Mice (2006) (124)
- The role of H2S bioavailability in endothelial dysfunction. (2015) (123)
- Mitochondrial NO and reactive nitrogen species production: does mtNOS exist? (2006) (123)
- Decrease of the inflammatory response and induction of the Akt/protein kinase B pathway by poly-(ADP-ribose) polymerase 1 inhibitor in endotoxin-induced septic shock. (2003) (121)
- Purines inhibit poly(ADP‐ribose) polymerase activation and modulate oxidant‐induced cell death (2001) (120)
- Gaseotransmitters: New Frontiers for Translational Science (2010) (119)
- Regulation of the expression of the inducible isoform of nitric oxide synthase. (1995) (118)
- Role of peroxynitrite and neuronal nitric oxide synthase in the activation of poly(ADP-ribose) synthetase in a murine model of cerebral ischemia-reperfusion (1998) (118)
- Protective effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalation. (2008) (116)
- The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5'-N-methyluronamide, is protective in two murine models of colitis. (2003) (116)
- Adenosine receptor activation ameliorates type 1 diabetes (2007) (116)
- An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice. (2001) (113)
- Regulation of Vascular Tone, Angiogenesis and Cellular Bioenergetics by the 3-Mercaptopyruvate Sulfurtransferase/H2S Pathway: Functional Impairment by Hyperglycemia and Restoration by dl-α-Lipoic Acid (2015) (113)
- Hydrogen sulfide decreases adenosine triphosphate levels in aortic rings and leads to vasorelaxation via metabolic inhibition. (2008) (110)
- PATHOPHYSIOLOGICAL ROLES OF PEROXYNITRITE IN CIRCULATORY SHOCK (2010) (110)
- Role of poly(ADP-ribose)synthetase in inflammation. (1998) (110)
- Bacterial induction of inducible nitric oxide synthase in cultured human intestinal epithelial cells. (1998) (109)
- Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB. (2004) (109)
- Identification of Conserved Domains in Salmonella muenchen Flagellin That Are Essential for Its Ability to Activate TLR5 and to Induce an Inflammatory Response in Vitro* (2004) (109)
- Gallotannin Inhibits the Expression of Chemokines and Inflammatory Cytokines in A549 Cellss⃞ (2005) (108)
- Endogenous peroxynitrite is involved in the inhibition of mitochondrial respiration in immuno-stimulated J774.2 macrophages. (1995) (108)
- Effect of Hydrogen Sulfide in a Porcine Model of Myocardial Ischemia-Reperfusion: Comparison of Different Administration Regimens and Characterization of the Cellular Mechanisms of Protection (2009) (108)
- Potential role of poly(adenosine 5′-diphosphate-ribose) polymerase activation in the pathogenesis of myocardial contractile dysfunction associated with human septic shock (2006) (108)
- HEMODYNAMIC AND METABOLIC EFFECTS OF HYDROGEN SULFIDE DURING PORCINE ISCHEMIA/REPERFUSION INJURY (2008) (107)
- Flagellin from Gram-Negative Bacteria is a Potent Mediator of Acute Pulmonary Inflammation in Sepsis (2003) (107)
- Identification of poly‐ADP‐ribosylated mitochondrial proteins after traumatic brain injury (2008) (107)
- Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep. (2002) (106)
- Potential role for 8‐oxoguanine DNA glycosylase in regulating inflammation (2005) (106)
- Rapid ‘glycaemic swings’ induce nitrosative stress, activate poly(ADP-ribose) polymerase and impair endothelial function in a rat model of diabetes mellitus (2009) (105)
- Protective effect of a novel, potent inhibitor of poly(adenosine 5′-diphosphate-ribose) synthetase in a porcine model of severe bacterial sepsis* (2002) (104)
- Dual role of poly(ADP‐ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells (2009) (104)
- Peroxynitrite causes energy depletion and increases permeability via activation of poly (ADP-ribose) synthetase in pulmonary epithelial cells. (1997) (103)
- Gender Differences in the Endotoxin-Induced Inflammatory and Vascular Responses: Potential Role of Poly(ADP-ribose) Polymerase Activation (2005) (102)
- Poly(ADP-Ribose) Polymerase Promotes Cardiac Remodeling, Contractile Failure, and Translocation of Apoptosis-Inducing Factor in a Murine Experimental Model of Aortic Banding and Heart Failure (2005) (102)
- Detection of exhaled hydrogen sulphide gas in healthy human volunteers during intravenous administration of sodium sulphide. (2010) (101)
- Nitric Oxide: an Important Articular Free Radical* (1996) (101)
- Poly(ADP-ribose) synthetase activation mediates increased permeability induced by peroxynitrite in Caco-2BBe cells. (1998) (100)
- Blockade of Poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis. (1999) (100)
- Hyperosmotic stress induces nuclear factor-kappaB activation and interleukin-8 production in human intestinal epithelial cells. (2002) (99)
- Diabetes‐induced overexpression of endothelin‐1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP‐ribose) polymerase activation (2003) (99)
- Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure. (2002) (98)
- Effect of genetic disruption of poly (ADP-ribose) synthetase on delayed production of inflammatory mediators and delayed necrosis during myocardial ischemia-reperfusion injury. (2000) (98)
- Heart mitochondria contain functional ATP-dependent K+ channels. (2003) (96)
- A dual role for poly‐ADP‐ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14‐3‐3γ (2003) (95)
- Proinflammatory cytokines depress cardiac efficiency by a nitric oxide-dependent mechanism. (1998) (95)
- Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models (2006) (94)
- Inosine reduces inflammation and improves survival in a murine model of colitis. (2003) (93)
- Investigation of the subunit composition and the pharmacology of the mitochondrial ATP-dependent K+ channel in the brain (2003) (93)
- Detection of Poly(ADP-ribose) Polymerase Activation in Oxidatively Stressed Cells and Tissues Using Biotinylated NAD Substrate (2002) (93)
- Poly (ADP-ribose) synthetase mediates intestinal mucosal barrier dysfunction after mesenteric ischemia. (1998) (92)
- Cystathionine-β-synthase: Molecular Regulation and Pharmacological Inhibition (2020) (92)
- Inosine reduces systemic inflammation and improves survival in septic shock induced by cecal ligation and puncture. (2001) (91)
- Disruption of the actin cytoskeleton results in nuclear factor‐κB activation and inflammatory mediator production in cultured human intestinal epithelial cells (2004) (91)
- The synthesis and functional evaluation of a mitochondria-targeted hydrogen sulfide donor, (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)decyl) triphenylphosphonium bromide (AP39) (2014) (91)
- Poly (ADP‐ribose) polymerase‐1 is a key mediator of liver inflammation and fibrosis (2014) (90)
- Endothelial dysfunction in aging animals: the role of poly(ADP‐ribose) polymerase activation (2002) (90)
- Anti‐inflammatory effects of PJ34, a poly(ADP‐ribose) polymerase inhibitor, in transient focal cerebral ischemia in mice (2006) (89)
- Transcriptional regulation of human inducible nitric oxide synthase gene in an intestinal epithelial cell line. (1997) (89)
- Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation. (1998) (89)
- Isoproterenol Inhibits IL-10, TNF-α, and Nitric Oxide Production in RAW 264.7 Macrophages (1998) (89)
- Nitric oxide and shock. (1997) (89)
- Effect of L‐buthionine‐(S,R)‐sulphoximine, an inhibitor of γ‐glutamylcysteine synthetase on peroxynitrite‐ and endotoxic shock‐induced vascular failure (1998) (89)
- Peroxynitrite production and activation of poly (adenosine diphosphate‐ribose) synthetase in spinal cord injury (1999) (87)
- Consensus Molecular Subtypes of Colorectal Cancer and their Clinical Implications. (2017) (87)
- Roles of poly(ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications. (2005) (87)
- Stimulation of β-adrenoceptors inhibits endotoxin-induced IL-12 production in normal and IL-10 deficient mice (1998) (87)
- Nicotine reduces the incidence of type I diabetes in mice. (2002) (87)
- Inosine Exerts a Broad Range of Antiinflammatory Effects in a Murine Model of Acute Lung Injury (2002) (86)
- Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform (1996) (86)
- Suppression of poly (ADP‐ribose) polymerase activation by 3‐aminobenzamide in a rat model of myocardial infarction: long‐term morphological and functional consequences (2001) (86)
- cDNA Microarray Analysis Reveals a Nuclear Factor-κB-Independent Regulation of Macrophage Function by Adenosine (2003) (85)
- Peroxynitrite Is a Mediator of Cytokine-Induced Destruction of Human Pancreatic Islet β Cells (2001) (85)
- Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro. (2013) (84)
- Exogenous and endogenous catecholamines inhibit the production of macrophage inflammatory protein (MIP) 1α via a β adrenoceptor mediated mechanism (1998) (84)
- AP39, A Mitochondrially Targeted Hydrogen Sulfide Donor, Exerts Protective Effects in Renal Epithelial Cells Subjected to Oxidative Stress in Vitro and in Acute Renal Injury in Vivo (2016) (84)
- Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells (2018) (83)
- Low-dose poly(ADP-ribose) polymerase inhibitor-containing combination therapies reverse early peripheral diabetic neuropathy. (2005) (83)
- Hydrogen sulfide-mediated stimulation of mitochondrial electron transport involves inhibition of the mitochondrial phosphodiesterase 2A, elevation of cAMP and activation of protein kinase A. (2013) (83)
- Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis. (2017) (82)
- Nifedipine inhibits the induction of nitric oxide synthase by bacterial lipopolysaccharide. (1993) (82)
- Mitochondrial-to-nuclear translocation of apoptosis-inducing factor in cardiac myocytes during oxidant stress: potential role of poly(ADP-ribose) polymerase-1. (2004) (82)
- Pathophysiologic role of oxidative stress-induced poly(ADP-ribose) polymerase-1 activation: focus on cell death and transcriptional regulation. (2005) (81)
- Matrix metalloproteinase activation is an early event in doxorubicin-induced cardiotoxicity. (2004) (81)
- Protection by inhibition of poly (ADP-ribose) synthetase against oxidant injury in cardiac myoblasts In vitro. (1997) (81)
- Poly(ADP-ribose) polymerase activation by reactive nitrogen species--relevance for the pathogenesis of inflammation. (2006) (80)
- A New, Potent Poly(ADP-ribose) Polymerase Inhibitor Improves Cardiac and Vascular Dysfunction Associated with Advanced Aging (2004) (80)
- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors (2021) (79)
- Angiotensin II-Mediated Endothelial Dysfunction: Role of Poly(ADP-ribose) Polymerase Activation (2004) (79)
- Comparison of Inflammation, Organ Damage, and Oxidant Stress Induced by Salmonella enterica Serovar Muenchen Flagellin and Serovar Enteritidis Lipopolysaccharide (2002) (79)
- Requirement of intracellular calcium mobilization for peroxynitrite-induced poly(ADP-ribose) synthetase activation and cytotoxicity. (1999) (79)
- Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy (2008) (78)
- Interleukin-1 contributes to the induction of nitric oxide synthase by endotoxin in vivo. (1993) (78)
- Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure. (2006) (77)
- The Therapeutic Effects of PJ34 [N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a Selective Inhibitor of Poly(ADP-Ribose) Polymerase, in Experimental Allergic Encephalomyelitis Are Associated with Immunomodulation (2004) (77)
- Crucial role of apopain in the peroxynitrite-induced apoptotic DNA fragmentation. (1998) (77)
- Circulating methemoglobin and nitrite/nitrate concentrations as indicators of nitric oxide overproduction in critically ill children with septic shock. (1997) (76)
- Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy (2004) (76)
- Cystathionine &ggr; Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis (2019) (75)
- Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress. (2012) (75)
- Poly(ADP-ribose) polymerase activation in the reperfused myocardium. (2004) (75)
- Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation (2017) (75)
- Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics (2016) (75)
- Blockade of poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis (1999) (75)
- Regulation and role of endogenously produced hydrogen sulfide in angiogenesis. (2016) (74)
- Hydrogen sulfide: an endogenous regulator of the immune system. (2020) (74)
- Inhibition of Poly (ADP-ribose) Polymerase Attenuates Acute Lung Injury in an Ovine Model of Sepsis (2004) (74)
- Mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, reduces trinitrobenzene sulfonic acid-induced colonic damage in rats. (1998) (74)
- Dopamine suppresses IL-12 p40 production by lipopolysaccharide-stimulated macrophages via a β-adrenoceptor-mediated mechanism (2002) (73)
- Nitric oxide‐peroxynitrite‐poly(ADP‐ribose) polymerase pathway in the skin (2002) (73)
- Inhibition by spermine of the induction of nitric oxide synthase in J774.2 macrophages: requirement of a serum factor (1994) (73)
- Activation of poly(ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging. (2002) (72)
- Spermine differentially regulates the production of interleukin-12 p40 and interleukin-10 and suppresses the release of the T helper 1 cytokine interferon-gamma. (2000) (72)
- Novel modulators of poly(ADP-ribose) polymerase. (2006) (71)
- POTENTIAL ROLE OF THE PEROXYNITRITE‐POLY(ADP‐RIBOSE) SYNTHETASE PATHWAY IN A RAT MODEL OF SEVERE HEMORRHAGIC SHOCK (1998) (71)
- Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function (2014) (70)
- Peroxynitrite production, DNA breakage, and poly(ADP-ribose) polymerase activation in a mouse model of oxazolone-induced contact hypersensitivity. (2001) (70)
- Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide. (2016) (70)
- Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway. (2013) (70)
- Overproduction of H2S, generated by CBS, inhibits mitochondrial Complex IV and suppresses oxidative phosphorylation in Down syndrome (2019) (70)
- Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: preclinical studies in a murine model of cecal ligation and puncture (2014) (70)
- Suppression of IL‐12 production by phosphodiesterase inhibition in murine endotoxemia is IL‐10 independent (1998) (70)
- Discovery of potent poly(ADP-ribose) polymerase-1 inhibitors from the modification of indeno[1,2-c]isoquinolinone. (2005) (69)
- Detection of exhaled hydrogen sulphide gas in rats exposed to intravenous sodium sulphide (2009) (69)
- Inosine improves gut permeability and vascular reactivity in endotoxic shock (2001) (69)
- Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway. (2015) (69)
- Poly(ADP-ribose) polymerase inhibition protect neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke. (2004) (68)
- ATP suppression of interleukin‐12 and tumour necrosis factor‐α release from macrophages (2000) (68)
- Lipocortin 1 protects against splanchnic artery occlusion and reperfusion injury by affecting neutrophil migration. (1997) (68)
- Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms (2016) (67)
- Contribution of Poly(ADP-Ribose) Polymerase to Postischemic Blood—Brain Barrier Damage in Rats (2007) (67)
- IL‐12 as a therapeutic target for pharmacological modulation in immune‐mediated and inflammatory diseases: regulation of T helper 1/T helper 2 responses (1999) (66)
- Collagen induced arthritis: reversal by mercaptoethylguanidine, a novel antiinflammatory agent with a combined mechanism of action. (1998) (66)
- Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor. (2002) (65)
- Inhibition of angiogenesis by the poly(ADP-ribose) polymerase inhibitor PJ-34. (2008) (65)
- NHE blockade inhibits chemokine production and NF-kappaB activation in immunostimulated endothelial cells. (2002) (65)
- Bacterial Invasion Is Not Required for Activation of NF-κB in Enterocytes (1999) (64)
- Mitochondrial poly(ADP-ribose) polymerase: The Wizard of Oz at work. (2016) (64)
- K(ATP)-channel inhibition improves hemodynamics and cellular energetics in hemorrhagic shock. (1997) (64)
- Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression. (2004) (64)
- Cardiac and metabolic effects of hypothermia and inhaled hydrogen sulfide in anesthetized and ventilated mice* (2010) (63)
- Protection against hypoxia-reoxygenation in the absence of poly (ADP-ribose) synthetase in isolated working hearts. (1999) (63)
- Modification of energy metabolism and radiation response of a murine tumour by changes in nitric oxide availability. (1993) (63)
- S‐nitrosoglutathione‐containing hydrogel increases dermal blood flow in streptozotocin‐induced diabetic rats (2007) (63)
- Effect of interleukin‐4 and interleukin‐10 on leucocyte migration and nitric oxide production in the mouse (1995) (63)
- Poly(ADP-Ribose) Polymerase Contributes to the Development of Myocardial Infarction in Diabetic Rats and Regulates the Nuclear Translocation of Apoptosis-Inducing Factor (2004) (63)
- PROTECTIVE EFFECTS OF NICOTINAMIDE AGAINST NITRIC OXIDE‐MEDIATED DELAYED VASCULAR FAILURE IN ENDOTOXIC SHOCK: POTENTIAL INVOLVEMENT OF polyADP RIBOSYL SYNTHETASE (1996) (62)
- Drug resistance induces the upregulation of H2S‐producing enzymes in HCT116 colon cancer cells (2017) (61)
- Adenosine: a potential mediator of immunosuppression in multiple organ failure. (2002) (61)
- Time-Dependent and Organ-Specific Changes in Mitochondrial Function, Mitochondrial DNA Integrity, Oxidative Stress and Mononuclear Cell Infiltration in a Mouse Model of Burn Injury (2015) (61)
- Radiosensitization of human and rodent cell lines by INO-1001, a novel inhibitor of poly(ADP-ribose) polymerase. (2004) (60)
- Poly (adp-ribose) polymerase inhibitors as potential therapeutic agents in stroke and neurotrauma. (2005) (60)
- Altered calcium handling is an early sign of streptozotocin-induced diabetic cardiomyopathy. (2006) (60)
- Effects of poly(ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma. (2004) (59)
- Lithium Induces NF-κB Activation and Interleukin-8 Production in Human Intestinal Epithelial Cells* (2002) (59)
- The mechanism of the inhibitory effect of polyamines on the induction of nitric oxide synthase: role of aldehyde metabolites (1994) (59)
- Poly(ADP-ribose) Polymerase is a Regulator of Chemokine Production: Relevance for the Pathogenesis of Shock and Inflammation (2002) (59)
- Effects of Intravenous Sulfide During Porcine Aortic Occlusion-Induced Kidney Ischemia/Reperfusion Injury (2011) (59)
- Activation of soluble guanylyl cyclase by a factor other than nitric oxide or carbon monoxide contributes to the vascular hyporeactivity to vasoconstrictor agents in the aorta of rats treated with endotoxin. (1994) (59)
- Inhibition of Mitochondrial Bioenergetics by Esterase-Triggered COS/H2S Donors. (2017) (58)
- Pharmacological characterization of guanidinoethyldisulphide (GED), a novel inhibitor of nitric oxide synthase with selectivity towards the inducible isoform (1996) (58)
- Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase and pleiotropic modifier of cellular signal pathways. (1997) (58)
- Evidence for Reactive Nitrogen Species Formation in the Gingivomucosal Tissue (2001) (58)
- Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H2S) pathway in cancer cells. (2020) (58)
- Local administration of the poly(ADP-ribose) polymerase inhibitor INO-1001 prevents NAD+ depletion and improves water maze performance after traumatic brain injury in mice. (2007) (57)
- NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes. (2002) (57)
- Evidence for the expression of cyclooxygenase-2 enzyme in periodontitis. (2001) (57)
- Critical role of reactive nitrogen species in lung ischemia-reperfusion injury. (2003) (57)
- Disruption of the actin cytoskeleton results in nuclear factor‐κB activation and inflammatory mediator production in cultured human intestinal epithelial cells (2004) (57)
- Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach (2016) (56)
- PARP as a Drug Target for the Therapy of Diabetic Cardiovascular Dysfunction. (2002) (56)
- Nitric oxide in skeletal muscle: inhibition of nitric oxide synthase inhibits walking speed in rats. (2001) (56)
- Single dose treatment with PARP-inhibitor INO-1001 improves aging-associated cardiac and vascular dysfunction (2007) (56)
- The impact of lead and cadmium on selected motility, prooxidant and antioxidant parameters of bovine seminal plasma and spermatozoa (2013) (56)
- Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects (2019) (56)
- Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro. (2001) (55)
- Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer (2016) (55)
- Sulphasalazine inhibits macrophage activation: inhibitory effects on inducible nitric oxide synthase expression, interleukin‐12 production and major histocompatibility complex II expression (2001) (55)
- Inventing new therapies without reinventing the wheel: the power of drug repurposing (2018) (55)
- Hydrogen Sulfide Is an Antiviral and Antiinflammatory Endogenous Gasotransmitter in the Airways. Role in Respiratory Syncytial Virus Infection. (2016) (55)
- Effects of a novel guanylyl cyclase inhibitor on the vascular actions of nitric oxide and peroxynitrite in immunostimulated smooth muscle cells and in endotoxic shock. (1999) (54)
- H2S during circulatory shock: some unresolved questions. (2014) (54)
- H2S‐induced S‐sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells (2017) (54)
- Thioglycine and L-thiovaline: biologically active H₂S-donors. (2012) (54)
- Na+/H+ exchanger blockade inhibits enterocyte inflammatory response and protects against colitis. (2002) (54)
- Cardioprotective effects of poly(ADP-ribose) polymerase inhibition. (2005) (54)
- Hydrogen sulfide attenuates cytokine production through the modulation of chromatin remodeling (2015) (54)
- Regulation of macrophage inflammatory protein-1 alpha expression and function by endogenous interleukin-10 in a model of acute inflammation. (1999) (53)
- Activation of Poly(ADP-Ribose) Polymerase by Myocardial Ischemia and Coronary Reperfusion in Human Circulating Leukocytes (2006) (53)
- Role of poly(ADP-ribose) polymerase activation in endotoxin-induced cardiac collapse in rodents. (2002) (53)
- Importance of basal nitric oxide synthesis in regulation of myocardial blood flow. (1991) (53)
- Poly(ADP-ribose) polymerase regulates myocardial calcium handling in doxorubicin-induced heart failure. (2005) (52)
- Protective effects of 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase against peroxynitrite-induced glial damage and stroke development. (1998) (51)
- Role of Hydrogen Sulfide in Paramyxovirus Infections (2015) (51)
- Beneficial effect of a hydrogen sulphide donor (sodium sulphide) in an ovine model of burn‐ and smoke‐induced acute lung injury (2009) (51)
- Indices of Apoptosis Activation After Blood Cardioplegia and Cardiopulmonary Bypass (2006) (49)
- Effect of hydrogen sulfide on myocardial protection in the setting of cardioplegia and cardiopulmonary bypass. (2010) (49)
- Nitrative stress and poly(ADP-ribose) polymerase activation in healthy and gestational diabetic pregnancies (2009) (49)
- INTERLEUKIN‐1β AND INTERFERON‐γ REGULATE INTERLEUKIN‐6 PRODUCTION IN CULTURED HUMAN INTESTINAL EPITHELIAL CELLS (1997) (49)
- Poly(ADP-ribose) polymerase as a drug target for cardiovascular disease and cancer: an update. (2007) (49)
- Part II: Beneficial Effects of the Peroxynitrite Decomposition Catalyst FP15 in Murine Models of Arthritis and Colitis (2002) (49)
- Dihydropyridine antagonists and agonists of calcium channels inhibit the induction of nitric oxide synthase by endotoxin in cultured macrophages. (1993) (49)
- Effects of intravenous sulfide during resuscitated porcine hemorrhagic shock* (2012) (49)
- Characterization of AQX‐1125, a small‐molecule SHIP1 activator (2013) (49)
- Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation (2001) (48)
- Complement Component C3 Production in IL-1β-Stimulated Human Intestinal Epithelial Cells Is Blocked by NF-κB Inhibitors and by Transfection with Ser 32/36 Mutant IκBα (1999) (48)
- Activation of the Poly(ADP-Ribose) Polymerase Pathway in Human Heart Failure (2006) (48)
- The discovery and synthesis of novel adenosine substituted 2,3-dihydro-1H-isoindol-1-ones: potent inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1). (2004) (48)
- Poly (ADP-ribose) polymerase inhibition prevents spontaneous and recurrent autoimmune diabetes in NOD mice by inducing apoptosis of islet-infiltrating leukocytes. (2003) (47)
- Cardiopulmonary, histologic, and inflammatory effects of intravenous Na2S after blunt chest trauma-induced lung contusion in mice. (2011) (47)
- Peroxynitrite‐induced oligodendrocyte toxicity is not dependent on poly(ADP‐ribose) polymerase activation (2003) (47)
- Cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis (2009) (47)
- Inosine Protects Against the Development of Diabetes in Multiple-Low-Dose Streptozotocin and Nonobese Diabetic Mouse Models of Type 1 Diabetes (2003) (47)
- Myocardial Ischemic Preconditioning in Rodents Is Dependent on Poly (ADP-Ribose) Synthetase (2001) (46)
- Induction of hypoxia in experimental murine tumors by the nitric oxide synthase inhibitor, NG-nitro-L-arginine. (1994) (46)
- Amelioration by mercaptoethylguanidine of the vascular and energetic failure in haemorrhagic shock in the anesthetised rat. (1997) (46)
- Poly(ADP-ribose) polymerase: a new therapeutic target? (2008) (46)
- Neuronal nitric oxide synthase inhibition attenuates cardiopulmonary dysfunctions after combined burn and smoke inhalation injury in sheep (2008) (45)
- Beneficial effects of mercaptoethylguanidine, an inhibitor of the inducible isoform of nitric oxide synthase and a scavenger of peroxynitrite, in a porcine model of delayed hemorrhagic shock. (1999) (45)
- Reduction of hemorrhagic transformation by PJ34, a poly(ADP-ribose)polymerase inhibitor, after permanent focal cerebral ischemia in mice. (2008) (45)
- gamma-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury. (2008) (45)
- Alpha7 cholinergic-agonist prevents systemic inflammation and improves survival during resuscitation (2008) (45)
- Beneficial effects of PJ34 and INO-1001, two novel water-soluble poly(ADP-ribose) polymerase inhibitors, on the consequences of traumatic brain injury in rat (2005) (45)
- Inhibition of poly(adenosine diphosphate-ribose) polymerase by the active form of vitamin D. (2007) (45)
- Inhibition of ATP-activated potassium channels exerts pressor effects and improves survival in a rat model of severe hemorrhagic shock. (1996) (45)
- Partial protection by poly(ADP-ribose) polymerase inhibitors from nitroxyl-induced cytotoxity in thymocytes. (2001) (45)
- Immunohistochemical Localization of Protein 3-Nitrotyrosine and S-nitrosocysteine in a Murine Model of Inhaled Nitric Oxide Therapy (2000) (44)
- Modulation of lipopolysaccharide-induced tumor necrosis factor-alpha and nitric oxide production by dopamine receptor agonists and antagonists in mice. (1996) (44)
- Cell-Based Screening Identifies Paroxetine as an Inhibitor of Diabetic Endothelial Dysfunction (2013) (44)
- Differentiation-Associated Downregulation of Poly(ADP-Ribose) Polymerase-1 Expression in Myoblasts Serves to Increase Their Resistance to Oxidative Stress (2015) (44)
- Adenosine stimulates CREB activation in macrophages via a p38 MAPK-mediated mechanism. (2004) (43)
- Role of Akt Activation in PARP Inhibitor Resistance in Cancer (2020) (43)
- Lack of mitochondrial nitric oxide production in the mouse brain (2004) (43)
- Glucocorticoids Suppress Mitochondrial Oxidant Production via Upregulation of Uncoupling Protein 2 in Hyperglycemic Endothelial Cells (2016) (42)
- A novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs. (2002) (42)
- Role of intracellular calcium mobilization and cell-density-dependent signaling in oxidative-stress-induced cytotoxicity in HaCaT keratinocytes. (2003) (42)
- Poly (ADP-ribose) synthetase activation mediates pulmonary microvascular and intestinal mucosal dysfunction in endotoxin shock. (1998) (42)
- Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform. (1995) (42)
- Poly(ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by reactive oxidant hydrogen peroxide in vitro. (2007) (42)
- Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics in Murine Colon Cancer Cells (2020) (41)
- Ursodeoxycholate inhibits induction of NOS in human intestinal epithelial cells and in vivo. (1997) (41)
- Influence of PARP-1 polymorphisms in patients after traumatic brain injury. (2010) (41)
- LOW‐LEVEL EXPRESSION AND LIMITED ROLE FOR THE INDUCIBLE ISOFORM OF NITRIC OXIDE SYNTHASE IN THE VASCULAR HYPOREACTIVITY AND MORTALITY ASSOCIATED WITH CECAL LIGATION AND PUNCTURE IN THE RAT (1996) (41)
- MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells. (2006) (40)
- Role of Nitric Oxide in Endotoxic Shock a : An Overview of Recent Advances (1998) (40)
- Mitochondria produce reactive nitrogen species via an arginine-independent pathway (2006) (40)
- Effects of a Potent Peroxynitrite Decomposition Catalyst in Murine Models of Endotoxemia and Sepsis (2011) (40)
- Restoration of the endothelial function in the aortic rings of apolipoprotein E deficient mice by pharmacological inhibition of the nuclear enzyme poly(ADP-ribose) polymerase. (2004) (40)
- INO-1001 A NOVEL POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITOR IMPROVES CARDIAC AND PULMONARY FUNCTION AFTER CRYSTALLOID CARDIOPLEGIA AND EXTRACORPORAL CIRCULATION (2004) (40)
- THE PARP-1 INHIBITOR INO-1001 FACILITATES HEMODYNAMIC STABILIZATION WITHOUT AFFECTING DNA REPAIR IN PORCINE THORACIC AORTIC CROSS-CLAMPING-INDUCED ISCHEMIA/REPERFUSION (2006) (39)
- THE EFFECT OF INDUCIBLE NITRIC OXIDE SYNTHASE (iNOS) INHIBITION ON SMOKE INHALATION INJURY IN SHEEP (2000) (39)
- Inhibition of poly(ADP‐ribose) synthetase (PARS) and protection against peroxynitrite‐induced cytotoxicity by zinc chelation (1999) (39)
- Hydrogen Sulfide, an Endogenous Stimulator of Mitochondrial Function in Cancer Cells (2021) (39)
- Proteasome Inhibitors Induce Inhibitory κB (IκB) Kinase Activation, IκBα Degradation, and Nuclear Factor κB Activation in HT-29 Cells (2004) (39)
- 3‐AMINOBENZAMIDE, AN INHIBITOR OF POLY (ADP‐RIBOSE) SYNTHETASE, IMPROVES HEMODYNAMICS AND PROLONGS SURVIVAL IN A PORCINE MODEL OF HEMORRHAGIC SHOCK (1998) (39)
- Facile and convenient syntheses of 6,11-dihydro-5H-indeno[1,2-c]isoquinolin- 5-ones and 6,11-dihydro-5H-indolo[3,2-c]isoquinolin-5-one. (2005) (39)
- H2S, a Bacterial Defense Mechanism against the Host Immune Response (2018) (38)
- Oxidant-induced cardiomyocyte injury: identification of the cytoprotective effect of a dopamine 1 receptor agonist using a cell-based high-throughput assay. (2007) (38)
- DIFFERENTIAL EFFECTS OF HYPEROXIA ON THE INDUCIBLE AND CONSTITUTIVE ISOFORMS OF NITRIC OXIDE SYNTHASE IN THE LUNG (1997) (38)
- Stimulation of beta-adrenoceptors inhibits endotoxin-induced IL-12 production in normal and IL-10 deficient mice. (1998) (38)
- Intra-mitochondrial poly(ADP-ribosyl)ation: potential role for alpha-ketoglutarate dehydrogenase. (2009) (38)
- BCL-2 protects peroxynitrite-treated thymocytes from poly(ADP-ribose) synthase (PARS)-independent apoptotic but not from PARS-mediated necrotic cell death. (2000) (37)
- Endogenously produced hydrogen sulfide supports tumor cell growth and proliferation (2013) (37)
- Endogenously produced peroxynitrite induces the oxidation of mitochondrial and nuclear proteins in immunostimulated macrophages (1997) (37)
- Protective Mechanisms of a Metalloporphyrinic Peroxynitrite Decomposition Catalyst, WW85, in Rat Cardiac Transplants (2005) (37)
- A cell-microelectronic sensing technique for the screening of cytoprotective compounds. (2010) (37)
- Poly(ADP-ribose) polymerase inhibition improves postischemic myocardial function after cardioplegia-cardiopulmonary bypass. (2003) (37)
- Inhibition of Nitric Oxide–Stimulated Vasorelaxation by Carbon Monoxide-Releasing Molecules (2011) (37)
- Mechanisms of cell necrosis. (2005) (37)
- The pathogenesis of diabetic complications: the role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity. (2005) (37)
- Inhibition of the production of nitric oxide and vasodilator prostaglandins attenuates the cardiovascular response to bacterial endotoxin in adrenalectomized rats (1993) (36)
- Poly(ADP-ribose) polymerase activity contributes to peroxynitrite-induced spinal cord neuronal cell death in vitro. (2004) (36)
- Cytoprotective effect of gallotannin in oxidatively stressed HaCaT keratinocytes: the role of poly(ADP‐ribose) metabolism (2004) (36)
- Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock (2016) (36)
- Identification of Pharmacological Modulators of HMGB1-Induced Inflammatory Response by Cell-Based Screening (2013) (35)
- 3‐Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics (2020) (35)
- ATP suppression of interleukin-12 and tumour necrosis factor-alpha release from macrophages. (2000) (35)
- Intratracheal instillation of a novel NO/nucleophile adduct selectively reduces pulmonary hypertension. (1997) (35)
- Time Profile of Oxidative Stress and Neutrophil Activation in Ovine Acute Lung Injury and Sepsis (2012) (35)
- Contractile and Endothelium-Dependent Dilatory Responses of Cerebral Arteries at Various Extracellular Magnesium Concentrations (1991) (35)
- Primary role of superoxide anion generation in the cascade of events leading to endothelial dysfunction and damage in high glucose treated HUVEC. (2007) (35)
- Potential role of hydrogen sulfide in the pathogenesis of vascular dysfunction in septic shock. (2013) (35)
- ADENOSINE STIMULATES CREB ACTIVATION IN MACROPHAGES VIA A P38 MAPK‐MEDIATED MECHANISM: 165 (2003) (35)
- Antibodies raised against N'-terminal Pseudomonas aeruginosa flagellin prevent mortality in lethal murine models of infection. (2005) (35)
- Blocking mineralocorticoid receptor with spironolactone may have a wide range of therapeutic actions in severe COVID-19 disease (2020) (35)
- Role of poly(ADP-ribose) synthetase activation in the suppression of cellular energetics in response to nitric oxide and peroxynitrite. (1997) (34)
- Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase (2016) (34)
- Exogenous and endogenous catecholamines inhibit the production of macrophage inflammatory protein (MIP) 1 alpha via a beta adrenoceptor mediated mechanism. (1998) (34)
- Protein kinase C–dependent activation of NF-κB in enterocytes is independent of IκB degradation (1999) (34)
- Calcium entry blockers increase interleukin-10 production in endotoxemia. (1997) (34)
- Inhibition of nitric oxide synthase ameliorates cellular injury in sickle cell mouse kidneys. (2000) (34)
- Effects of inosine on reperfusion injury after heart transplantation. (2006) (33)
- Severe Burn Injury Induces Thermogenically Functional Mitochondria in Murine White Adipose Tissue (2015) (33)
- Regulation of Mitochondrial Poly(ADP-Ribose) Polymerase Activation by the β-Adrenoceptor/cAMP/Protein Kinase A Axis during Oxidative Stress (2014) (33)
- Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage (2013) (33)
- Activation of the Cholinergic Antiinflammatory Pathway Reduces Ricin-Induced Mortality and Organ Failure in Mice (2009) (33)
- Pathophysiological Roles of Nitric Oxide in Inflammation (2000) (33)
- Alterations in nitric oxide homeostasis during traumatic brain injury. (2017) (33)
- Characterization of AQX‐1125, a small‐molecule SHIP1 activator (2013) (33)
- Peroxynitrite decomposition catalyst, FP15, and poly(ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats (2004) (32)
- Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients. (2013) (32)
- 5-aminosalicylic acid inhibits iNOS transcription in human intestinal epithelial cells. (1999) (32)
- Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia. (2012) (31)
- Prevention of early myocardial depression in hyperdynamic endotoxemia in dogs. (2000) (31)
- Poly(Adenosine diphosphate-ribose) polymerase inhibition preserves erectile function in rats after cavernous nerve injury. (2005) (31)
- Pyrrolidinedithiocarbamate inhibits NF-kappaB activation and IL-8 production in intestinal epithelial cells. (2003) (31)
- Physiological roles of hydrogen sulfide in mammalian cells, tissues and organs. (2022) (31)
- Effect of the phosphodiesterase III inhibitor amrinone on cytokine and nitric oxide production in immunostimulated J774.1 macrophages. (1997) (31)
- Role of the peroxynitrite-poly (ADP-ribose) polymerase pathway in the pathogenesis of liver injury. (2006) (31)
- Inhibition of the Na(+)/H(+) antiporter suppresses IL-12 p40 production by mouse macrophages. (2001) (31)
- Inhibition of neuronal nitric oxide synthase in ovine model of acute lung injury* (2009) (31)
- Activation of the peroxynitrite-poly(adenosine diphosphate-ribose) polymerase pathway during neointima proliferation: a new target to prevent restenosis after endarterectomy. (2006) (31)
- AMRINONE AND THEOPHYLLINE DIFFERENTIALLY REGULATE CYTOKINE AND NITRIC OXIDE PRODUCTION IN ENDOTOXEMIC MICE (1997) (31)
- Modulation by dantrolene of endotoxin‐induced interleukin‐10, tumour necrosis factor‐α and nitric oxide production in vivo and in vitro (1998) (31)
- Treatment with insulin inhibits poly(ADP-ribose)polymerase activation in a rat model of endotoxemia. (2008) (31)
- Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages. (2002) (31)
- Oxidation, tyrosine nitration and cytostasis induction in the absence of inducible nitric oxide synthase. (1998) (30)
- PARP inhibition improves the effectiveness of neural stem cell transplantation in experimental brain trauma. (2003) (30)
- Overexpression of Cystathionine γ-Lyase Suppresses Detrimental Effects of Spinocerebellar Ataxia Type 3 (2015) (30)
- Pathomechanisms of myocardial dysfunction in sepsis. (2010) (30)
- The novel red-fluorescent probe DAR-4M measures reactive nitrogen species rather than NO. (2005) (29)
- Mitogen-activated protein kinase phosphorylation in kidneys of beta(s) sickle cell mice. (2000) (29)
- Hemorrhagic hypotension impairs endothelium-dependent relaxations in the renal artery of the cat. (1992) (29)
- Role of nitric oxide in physiology and patophysiology of periodontal tissues (1998) (29)
- Modulation of Poly(ADP-Ribose) Polymerase-1 (PARP-1)-Mediated Oxidative Cell Injury by Ring Finger Protein 146 (RNF146) in Cardiac Myocytes (2014) (29)
- Impact of Seminal Chemical Elements on the Oxidative Balance in Bovine Seminal Plasma and Spermatozoa (2013) (29)
- PARP inhibition induces Akt‐mediated cytoprotective effects through the formation of a mitochondria‐targeted phospho‐ATM‐NEMO‐Akt‐mTOR signalosome (2019) (28)
- Poly(ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates angiotensin AT2 receptor (AT2R) and AT2R binding protein (ATBP) genes. (2009) (28)
- Suppression of intestinal polyposis in Apcmin/+ mice by targeting the nitric oxide or poly(ADP-ribose) pathways. (2004) (28)
- THERAPEUTIC INJECTION OF PARP INHIBITOR INO-1001 PRESERVES CARDIAC FUNCTION IN PORCINE MYOCARDIAL ISCHEMIA AND REPERFUSION WITHOUT REDUCING INFARCT SIZE (2010) (28)
- Poly(ADP-Ribose) Polymerase Inhibition Improves Endothelial Dysfunction Induced by Hypochlorite (2007) (28)
- Systemic and Hepatosplanchnic Hemodynamic and Metabolic Effects of the PARP Inhibitor PJ34 During Hyperdynamic Porcine Endotoxemia (2003) (28)
- The Flagellin-TLR5 Axis: Therapeutic Opportunities. (2002) (28)
- Poly(ADP-ribose) polymerase inhibition attenuates biventricular reperfusion injury after orthotopic heart transplantation. (2005) (27)
- Both the H2S biosynthesis inhibitor aminooxyacetic acid and the mitochondrially targeted H2S donor AP39 exert protective effects in a mouse model of burn injury. (2016) (27)
- Protein kinase C protects from DNA damage‐induced necrotic cell death by inhibiting poly(ADP‐ribose) polymerase‐1 (2008) (27)
- Isoproterenol inhibits Il-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages. (1998) (27)
- Nebulization With &ggr;-Tocopherol Ameliorates Acute Lung Injury After Burn and Smoke Inhalation in the Ovine Model (2012) (27)
- Adenosine and inosine exert cytoprotective effects in an in vitro model of liver ischemia-reperfusion injury (2012) (27)
- Potential Pharmacological Chaperones for Cystathionine Beta-Synthase-Deficient Homocystinuria. (2018) (27)
- Reduction of liver ischemia-reperfusion injury via glutamine pretreatment. (2011) (27)
- beta-Adrenergic activation reveals impaired cardiac calcium handling at early stage of diabetes. (2005) (27)
- Reduced adipose tissue H2S in obesity (2017) (27)
- Anti-inflammatory adjuvant in resuscitation fluids improves survival in hemorrhage* (2009) (26)
- Pharmacological induction of mesenchymal-epithelial transition via inhibition of H2S biosynthesis and consequent suppression of ACLY activity in colon cancer cells. (2021) (26)
- Activation of Poly(ADP-Ribose) Polymerase in Circulating Leukocytes During Myocardial Infarction (2004) (26)
- Temperature and Cell-Type Dependency of Sulfide Effects on Mitochondrial Respiration (2012) (26)
- Poly (ADP-ribose) polymerase activation and circulatory shock. (2007) (26)
- Role of the L-arginine-nitric oxide pathway in the changes in cerebrovascular reactivity following hemorrhagic hypotension and retransfusion. (1992) (26)
- Inhibition of the induction of nitric oxide synthase by spermine is modulated by aldehyde dehydrogenase. (1994) (25)
- The selective poly(ADP)ribose-polymerase 1 inhibitor INO1001 reduces spinal cord injury during porcine aortic cross-clamping-induced ischemia/reperfusion injury (2007) (25)
- Complement component C3 production in IL-1beta-stimulated human intestinal epithelial cells is blocked by NF-kappaB inhibitors and by transfection with ser 32/36 mutant IkappaBalpha. (1999) (25)
- Short-term alanyl-glutamine dipeptide pretreatment in liver ischemia-reperfusion model: effects on microcirculation and antioxidant status in rats. (2007) (25)
- The re-emerging pathophysiological role of the cystathionine-β-synthase - hydrogen sulfide system in Down syndrome. (2020) (25)
- Potent inhibition of the inducible isoform of nitric oxide synthase by aminoethylisoselenourea and related compounds. (1996) (25)
- Pre-exposure to heat shock inhibits peroxynitrite-induced activation of poly(ADP) ribosyltransferase and protects against peroxynitrite cytotoxicity in J774 macrophages. (1996) (25)
- The clinically used PARP inhibitor olaparib improves organ function, suppresses inflammatory responses and accelerates wound healing in a murine model of third‐degree burn injury (2018) (24)
- THE ATP-SENSITIVE POTASSIUM-CHANNEL INHIBITOR GLIBENCLAMIDE IMPROVES OUTCOME IN AN OVINE MODEL OF HEMORRHAGIC SHOCK (2004) (24)
- Oxidative stress and regional ischemia-reperfusion injury: the peroxynitrite–poly(ADP-ribose) polymerase connection (2003) (24)
- Effects of S-isopropyl isothiourea, a potent inhibitor of nitric oxide synthase, in severe hemorrhagic shock. (1996) (24)
- Poly(adenosine diphosphate ribose) polymerase inhibition modulates spinal cord dysfunction after thoracoabdominal aortic ischemia-reperfusion. (2005) (24)
- The Combined Inducible Nitric Oxide Synthase Inhibitor and Free Radical Scavenger Guanidinoethyldisulfide Prevents Multiple Low-Dose Streptozotocin-Induced Diabetes In Vivo and Interleukin-1&bgr;-Induced Suppression of Islet Insulin Secretion In Vitro (2004) (24)
- Excessive stimulation of poly(ADP‐ribosyl)ation contributes to endothelial dysfunction in pre‐eclampsia (2005) (24)
- Il-1β Induction Of Nf-κb Activation In Human Intestinal Epithelial Cells Is Independent Of Oxyradical Signaling (2000) (24)
- Regulation of Kinase Cascade Activation and Heat Shock Protein Expression by Poly(ADP-ribose) Polymerase Inhibition in Doxorubicin-induced Heart Failure (2011) (24)
- S-substituted isothioureas are potent inhibitors of nitric oxide biosynthesis in cartilage. (1996) (23)
- Role of poly(ADP-ribose) polymerase activation in the pathogenesis of cardiopulmonary dysfunction in a canine model of cardiopulmonary bypass. (2004) (23)
- The Peroxynitrite Catalyst WW-85 Improves Pulmonary Function in Ovine Septic Shock (2011) (23)
- Hydrogen Sulfide Preserves Endothelial Nitric Oxide Synthase Function by Inhibiting Proline-Rich Kinase 2: Implications for Cardiomyocyte Survival and Cardioprotection (2017) (23)
- Molecular biological effects of selective neuronal nitric oxide synthase inhibition in ovine lung injury. (2010) (23)
- Gene expression reprogramming protects macrophage from septic-induced cell death. (2010) (23)
- Role of nitric oxide in myocardial dysfunction after combined burn and smoke inhalation injury. (2001) (23)
- Lung-protective effects of the metalloporphyrinic peroxynitrite decomposition catalyst WW-85 in interleukin-2 induced toxicity. (2008) (22)
- Complement C3 Production in Human Intestinal Epithelial Cells Is Regulated by Interleukin 1β and Tumor Necrosis Factor α (1997) (22)
- Mechanism of cystathionine-β-synthase inhibition by disulfiram: the role of bis(N,N-diethyldithiocarbamate)-copper(II). (2020) (22)
- Traumatic brain injury in mice deficient in poly-ADP(ribose) polymerase: a preliminary report. (2000) (22)
- Modulation of peroxynitrite‐ and hypochlorous acid‐induced inactivation of α1‐antiproteinase by mercaptoethylguanidine (1999) (22)
- Bacterial invasion is not required for activation of NF-kappaB in enterocytes. (1999) (22)
- Poly (ADP) ribose polymerase inhibition improves rat cardiac allograft survival. (2005) (22)
- Role of flagellin in the pathogenesis of shock and acute respiratory distress syndrome: Therapeutic opportunities (2003) (22)
- Increased Poly(ADP-Ribosyl)ation in Skeletal Muscle Tissue of Pediatric Patients with Severe Burn Injury: Prevention by Propranolol Treatment (2011) (22)
- Poly-ADP-ribosylation in health and disease (2005) (22)
- Cardiovascular disease and resuscitated septic shock lead to the downregulation of the H2S-producing enzyme cystathionine-γ-lyase in the porcine coronary artery (2017) (22)
- Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: role of PYK2 (2017) (22)
- ROLE OF PEROXYNITRITE IN THE PROTEIN OXIDATION AND APOPTOTIC DNA FRAGMENTATION IN VASCULAR SMOOTH MUSCLE CELLS STIMULATED WITH BACTERIAL LIPOPOLYSACCHARIDE AND INTERFERON‐&ggr; (1995) (22)
- Pharmacological inhibition of poly(ADP-ribose) polymerase in cardiovascular disorders: future directions. (2005) (21)
- The HIV Protease Inhibitor Saquinavir Inhibits HMGBl-Driven Inflammation by Targeting the Interaction of Cathepsin V with TLR4/MyD88 (2015) (21)
- Calcium channel blockers and dantrolene differentially regulate the production of interleukin-12 and interferon-γ in endotoxemic mice (1998) (21)
- Beneficial pulmonary effects of a metalloporphyrinic peroxynitrite decomposition catalyst in burn and smoke inhalation injury. (2011) (21)
- SHORT-TERM EFFECTS OF GLIPIZIDE (AN ADENOSINE TRIPHOSPHATE-SENSITIVE POTASSIUM CHANNEL INHIBITOR) ON CARDIOPULMONARY HEMODYNAMICS AND GLOBAL OXYGEN TRANSPORT IN HEALTHY AND ENDOTOXEMIC SHEEP (2006) (21)
- The effect of inducible nitric oxide synthase (iNOS) inhibition on smoke inhalation injury in sheep. (1999) (20)
- Quantification of Poly(ADP-Ribose)-Modified Proteins in Cerebrospinal Fluid from Infants and Children after Traumatic Brain Injury (2008) (20)
- Poly(ADP-ribose) polymerase mediates inflammation in a mouse model of contact hypersensitivity. (2009) (20)
- Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection (2018) (20)
- Upregulation and Mitochondrial Sequestration of Hemoglobin Occur in Circulating Leukocytes during Critical Illness, Conferring a Cytoprotective Phenotype (2015) (20)
- Lipid A and the lipid A analogue anti-tumour compound ONO-4007 induce nitric oxide synthase in vitro and in vivo. (1995) (20)
- Poly-ADP-ribose polymerase inhibition protects against myocardial and endothelial reperfusion injury after hypothermic cardiac arrest. (2003) (20)
- Detection of peroxynitrite-induced protein and DNA modifications. (2002) (20)
- Poly(ADP-ribose) polymerase and renal hypothermic preservation injury. (2004) (20)
- Effects of 7-ketocholesterol on the activity of endothelial poly(ADP-ribose) polymerase and on endothelium-dependent relaxant function. (2006) (20)
- Bacterial lysine decarboxylase influences human dental biofilm lysine content, biofilm accumulation, and subclinical gingival inflammation. (2012) (20)
- Hydrogen sulfide and PKG in ischemia–reperfusion injury: sources, signaling, accelerators and brakes (2015) (19)
- Human heart mitochondria do not produce physiologically relevant quantities of nitric oxide. (2007) (19)
- Effects of combined selective iNOS inhibition and peroxynitrite blockade during endotoxemia in pigs. (2001) (19)
- The Discovery and Synthesis of Novel Adenosine Substituted 2,3‐Dihydro‐1H‐isoindol‐1‐ones: Potent Inhibitors of Poly(ADP‐ribose) Polymerase‐1 (PARP‐1). (2004) (19)
- Role of the Activation of the Nuclear Enzyme Poly(ADP-Ribose) Polymerase in the Pathogenesis of Periodontitis (2003) (19)
- Modification of metabolism of transplantable and spontaneous murine tumors by the nitric oxide synthase inhibitor, nitro-L-arginine. (1994) (18)
- Activated neutrophils inhibit cerebrovascular endothelium-dependent relaxations in vitro. (1991) (18)
- Progesterone inhibits inducible nitric oxide synthase mRNA expression in human intestinal epithelial cells. (2000) (18)
- Development of a stretch‐induced neurotrauma model for medium‐throughput screening in vitro: identification of rifampicin as a neuroprotectant (2018) (18)
- Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation and Cellular Bioenergetics in Human Down Syndrome Fibroblasts (2020) (18)
- Catalytic peroxynitrite decomposition improves reperfusion injury after heart transplantation. (2012) (18)
- Intratracheal poly (ADP) ribose synthetase inhibition ameliorates lung ischemia reperfusion injury. (2004) (18)
- The anti-oxidative role of cytoglobin in podocytes: implications for a role in chronic kidney disease. (2020) (18)
- Methylene blue infusion in septic shock. (1995) (18)
- Emerging roles of cystathionine β-synthase in various forms of cancer (2022) (18)
- Proteasome inhibitors induce inhibitory kappa B (I kappa B) kinase activation, I kappa B alpha degradation, and nuclear factor kappa B activation in HT-29 cells. (2004) (17)
- Depression of the inotropic action of isoprenaline by nitric oxide synthase induction in rat isolated hearts. (1997) (17)
- Selenium-Binding Protein 1 (SELENBP1) Supports Hydrogen Sulfide Biosynthesis and Adipogenesis (2021) (17)
- Nicotinamide: a jack of all trades (but master of none?) (2003) (17)
- Salvage of nicotinamide adenine dinucleotide plays a critical role in the bioenergetic recovery of post‐hypoxic cardiomyocytes (2015) (17)
- Stent placement in patients with coronary heart disease decreases plasma levels of the endogenous nitric oxide synthase inhibitor ADMA. (2009) (17)
- Physiological concentrations of cyanide stimulate mitochondrial Complex IV and enhance cellular bioenergetics (2021) (16)
- Protein tyrosine nitration and poly(ADP-ribose) polymerase activation in N-methyl-N-nitro-N-nitrosoguanidine-treated thymocytes: implication for cytotoxicity. (2007) (16)
- Adenovirus infection increases iNOS and peroxynitrite production in the lung. (2001) (16)
- Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart (2018) (16)
- Regulation of the Expression of the Inducible Isoform of Nitric Oxide Synthase by Glucocorticoids a (1998) (16)
- Meta-analysis of metabolites involved in bioenergetic pathways reveals a pseudohypoxic state in Down syndrome (2020) (16)
- Parenteral administration of glipizide sodium salt, an inhibitor of adenosine triphosphate-sensitive potassium channels, prolongs short-term survival after severe controlled hemorrhage in rats* (2003) (16)
- Cystathionine-gamma-lyase deficient mice are protected against the development of multiorgan failure and exhibit reduced inflammatory response during burn. (2017) (16)
- Improvement of aging-associated cardiovascular dysfunction by the orally administered copper(II)-aspirinate complex. (2008) (16)
- Poly(ADP-Ribose) Polymerase Inhibition in Acute Lung Injury. A Reemerging Concept (2020) (15)
- Hydrogen Sulfide Contributes to Retinal Neovascularization in Ischemia-Induced Retinopathy (2016) (15)
- Sulfide-inhibition of mitochondrial respiration at very low oxygen concentrations. (2014) (15)
- Recombinant human activated protein C attenuates cardiovascular and microcirculatory dysfunction in acute lung injury and septic shock (2010) (15)
- The Role of Cystathionine-&ggr;-Lyase In Blunt Chest Trauma in Cigarette Smoke Exposed Mice (2017) (15)
- Olaparib, a clinically used poly(ADP-ribose) polymerase inhibitor protects against oxidant-induced cardiac myocyte death in vitro and improves cardiac contractility during early phase after heart transplantation in a rat model in vivo. (2017) (15)
- Biofilm Lysine Decarboxylase, a New Therapeutic Target for Periodontal Inflammation. (2015) (14)
- Hypothalamic blood flow remains unaltered following chronic nitric oxide synthase blockade in rats (1995) (14)
- Endotoxin tolerance: selective alterations in gene expression and protection against lymphocyte death. (2010) (14)
- Effect of mercaptoethylguanidine scavengers of peroxynitrite on the development of experimental allergic encephalomyelitis in PLSJL mice (2001) (14)
- Uptake and Release of Serotonin in Rat Cerebrovascular Nerves After Subarachnoid Hemorrhage (1992) (14)
- Na+,K+-ATPase activity is inhibited in cultured intestinal epithelial cells by endotoxin or nitric oxide. (2005) (14)
- Effect of PJ-34 PARP-inhibitor on rat liver microcirculation and antioxidant status. (2007) (14)
- Inhibition of experimental gingivitis in beagle dogs with topical mercaptoalkylguanidines. (2006) (14)
- THE NOVEL INOSINE ANALOGUE INO-2002 EXERTS AN ANTI-INFLAMMATORY EFFECT IN A MURINE MODEL OF ACUTE LUNG INJURY (2009) (14)
- Topical administration of a novel nitric oxide donor, linear polyethylenimine-nitric oxide/nucleophile adduct (DS1), selectively increases vaginal blood flow in anesthetized rats (2003) (14)
- Differential acute and chronic effects of burn trauma on murine skeletal muscle bioenergetics. (2016) (14)
- Mercaptoethylguanidine inhibits the inflammatory response in a murine model of chronic infection with Pseudomonas aeruginosa. (2000) (14)
- Enhanced peroxynitrite decomposition protects against experimental obliterative bronchiolitis. (2003) (14)
- Poly (ADP) ribose synthetase inhibition reduces obliterative airway disease in rat tracheal allografts. (2004) (14)
- Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome (2022) (14)
- Cooperative Interactions Between NO and H2S: Chemistry, Biology, Physiology, Pathophysiology (2017) (14)
- Sepsis induces Telomere Shortening: a Potential Mechanism Responsible for Delayed Pathophysiological Events in Sepsis Survivors? (2016) (14)
- Role of platelet-activating factor in the development of endothelial dysfunction in hemorrhagic hypotension and retransfusion. (1992) (13)
- Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation. (2000) (13)
- Hydrogen sulfide modulates chromatin remodeling and inflammatory mediator production in response to endotoxin, but does not play a role in the development of endotoxin tolerance (2016) (13)
- Poly (ADP) ribose synthetase inhibition in alveolar macrophages undergoing hypoxia and reoxygenation. (2008) (13)
- The Outsiders: Emerging Roles of Ectonucleotidases in Inflammation (2012) (13)
- Inhibition of nitric oxide synthase with pyrazole-1-carboxamidine and related compounds. (1997) (13)
- The Angiotensin-Converting Enzyme Inhibitor Captopril Inhibits Poly(Adp-Ribose) Polymerase Activation and Exerts Beneficial Effects in an Ovine Model of Burn and Smoke Injury (2011) (13)
- AQX‐1125, small molecule SHIP1 activator inhibits bleomycin‐induced pulmonary fibrosis (2017) (13)
- Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis (2018) (12)
- Effects of The Poly(ADP-ribose) Polymerase Inhibitor Olaparib in Cerulein-Induced Pancreatitis. (2020) (12)
- The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock (2019) (12)
- Role of poly(ADP-ribosyl)ation in a ‘two-hit’ model of hypoxia and oxidative stress in human A549 epithelial cells in vitro (2013) (12)
- Oxandrolone protects against the development of multiorgan failure, modulates the systemic inflammatory response and promotes wound healing during burn injury. (2019) (12)
- A cell-microelectronic sensing technique for the screening of cytoprotective compounds (2010) (12)
- Burn and Smoke Injury Activates Poly(ADP-ribose)polymerase in Circulating Leukocytes (2011) (12)
- Efficacy of Novel Aminooxyacetic Acid Prodrugs in Colon Cancer Models: Towards Clinical Translation of the Cystathionine β-Synthase Inhibition Concept (2021) (12)
- Immunomodulatory effects of poly(ADP-ribose) polymerase inhibition contribute to improved cardiac function and survival during acute cardiac rejection. (2006) (12)
- Protein kinase C-dependent activation of NF-kappaB in enterocytes is independent of IkappaB degradation. (1999) (11)
- Effects of FP15, a peroxynitrite decomposition catalyst on cardiac and pulmonary function after cardiopulmonary bypass. (2012) (11)
- In vitro effect of the potent poly(ADP-ribose) polymerase (PARP) inhibitor INO-1001 alone and in combination with aspirin, eptifibatide, tirofiban, enoxaparin or alteplase on haemostatic parameters. (2006) (11)
- The world according to poly(ADP-ribose) polymerase (PARP)—update 2006 (2006) (11)
- Role of poly (ADP) ribose synthetase in lung ischemia-reperfusion injury. (2004) (11)
- Mesenteric injury after cardiopulmonary bypass: Role of poly(adenosine 5′-diphosphate-ribose) polymerase* (2004) (11)
- Intraluminal Flagellin Differentially Contributes to Gut Dysbiosis and Systemic Inflammation following Burn Injury (2016) (11)
- Effect of superoxide dismutase on hemorrhagic hypotension and retransfusion-evoked middle cerebral artery endothelial dysfunction. (1994) (11)
- Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis. (2019) (11)
- Novel Aryl-Substituted Pyrimidones as Inhibitors of 3-Mercaptopyruvate Sulfurtransferase with Antiproliferative Efficacy in Colon Cancer. (2021) (11)
- Endothelium-dependent influence of small changes in extracellular magnesium concentration on the tone of feline middle cerebral arteries. (1991) (11)
- Interleukin-1 beta and interferon-gamma regulate interleukin-6 production in cultured human intestinal epithelial cells. (1997) (11)
- Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock (2017) (11)
- Immunomodulatory and Antibacterial Effects of Cystatin 9 against Francisella tularensis (2013) (11)
- Effects of coronary revascularization with or without cardiopulmonary bypass on plasma levels of asymmetric dimethylarginine (2011) (11)
- Q50, an iron-chelating and zinc-complexing agent, improves cardiac function in rat models of ischemia/reperfusion-induced myocardial injury. (2013) (11)
- Role of poly(ADP-ribose) polymerase (PARP) activation in the mitochondrial to nuclear translocation of apoptosis inducing factor (AIF) in stroke (2003) (10)
- The peroxynitrite catalyst WW-85 improves microcirculation in ovine smoke inhalation injury and septic shock. (2011) (10)
- The two faces of cyanide: an environmental toxin and a potential novel mammalian gasotransmitter (2021) (10)
- Aerosolized linear polyethylenimine-nitric oxide/nucleophile adduct attenuates endotoxin-induced lung injury in sheep. (2002) (10)
- IL-1beta induction of NF-kappaB activation in human intestinal epithelial cells is independent of oxyradical signaling. (2000) (10)
- The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes. (2008) (10)
- Changes in energy metabolism and X-ray sensitivity in murine tumours by the nitric oxide donor SIN-1. (1996) (10)
- NFκB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes (Journal of Endocrinology (2000) 173 (457-464)) (2010) (10)
- Quantification of PARP Activity in Human Tissues: Ex Vivo Assays in Blood Cells and Immunohistochemistry in Human Biopsies. (2017) (10)
- Pharmacological inhibition of poly(ADP-ribose) polymerase (PARP) (2003) (10)
- Effects of radiodetoxified endotoxin on nitric oxide production in J774 macrophages and in endotoxin shock (1996) (10)
- Poly(ADP-ribose) polymerase inhibition reverses vascular dysfunction after γ-irradiation (2006) (10)
- Isoflavone-mediated inhibition of tyrosine kinase: a novel antiinflammatory approach. (1999) (9)
- Does the activation of poly (ADP-ribose) synthetase mediate tissue injury in the sepsis induced by cecal ligation and puncture? Shock 16:137-142, 2001. (2002) (9)
- Inhibition of terminal calcium overload protects against peroxynitrite-induced cellular injury in macrophages. (1996) (9)
- Olaparib protects cardiomyocytes against oxidative stress and improves graft contractility during the early phase after heart transplantation in rats (2018) (9)
- Mechanism of hemoglobin-induced spasm in the isolated middle cerebral artery of the cat. (1989) (9)
- Comparison of the inhibitory effect of isothiourea and mercapto-alkylguanidine derivatives on the alternative pathways of arginine metabolism in macrophages. (1997) (9)
- Effects of stent implementation on plasma levels of asymmetric dimethylarginine in patients with or without ST-segment elevation acute myocardial infarction. (2010) (9)
- Role of endothelium in the responses of human intracranial arteries to a slight reduction of extracellular magnesium (1992) (9)
- Effects of Selective Nitric Oxide Synthase Inhibition in Hyperdynamic Endotoxemia in Dogs (1999) (9)
- Effects of cold or warm ischemia and ex-vivo lung perfusion on the release of damage associated molecular patterns and inflammatory cytokines in experimental lung transplantation. (2021) (9)
- Endothelial dysfunction as predictor of mortality in sepsis. (2011) (9)
- Effect of small changes in extracellular magnesium concentration on the tone of feline mesenteric arteries: involvement of endothelium. (1992) (9)
- Effect of Hemorrhagic Hypotension on Cerebrovascular Reactivity and infrastructure in the Cat (1991) (9)
- Hydroxyguanidines inhibit peroxynitrite-induced oxidation. (1998) (9)
- Emulsion stability and demulsification during the direct extraction of penicillin broth (1992) (9)
- Nitric oxide, intracellular calcium overload, and cytotoxicity. (1996) (9)
- Antiperoxynitrite strategies for the experimental therapy of shock. (2000) (8)
- Role of Peroxynitrite Anion in Renal Hypothermic Preservation Injury (2005) (8)
- Inhibition of poly(ADP-ribose)polymerase (PARP) by INO-1001 attenuates ovine acute lung injury in an ovine model of sepsis following smoke inhalation injury (2003) (8)
- Production of interleukin-12 is under the control of endogenous interleukin-10 in myocardial ischemia-reperfusion. (2001) (8)
- Cell death: The role of poly (ADP-ribose) polymerase (2000) (8)
- Contractile dysfunction in experimental cardiac allograft rejection: role of the poly (ADP‐ribose) polymerase pathway * (2006) (8)
- Infusion of sodium sulfide improves myocardial and endothelial function in a canine model of cardiopulmonary bypass (2007) (8)
- NADPH Diaphorase Histochemistry Detects Inducible Nitric Oxide Synthetase Activity in the Thymus of Naive and Staphylococcal Enterotoxin B-stimulated Mice (1998) (8)
- Complement C3 production in human intestinal epithelial cells is regulated by interleukin 1beta and tumor necrosis factor alpha. (1997) (8)
- Medicinal Chemistry and Therapeutic Applications of the Gasotransmitters NO, CO, and H2S and their Prodrugs (2010) (8)
- The hydrogen sulfide donor IK‐1001 stimulates neovascularization and improves wound healing (2008) (8)
- Calcium channel blockers and dantrolene differentially regulate the production of interleukin-12 and interferon-gamma in endotoxemic mice. (1998) (8)
- Effect of 3-mercaptopyruvate Sulfurtransferase Deficiency on the Development of Multiorgan Failure, Inflammation, and Wound Healing in Mice Subjected to Burn Injury. (2019) (8)
- Integrin-mediated suppression of endotoxin-induced DNA damage in lung endothelial cells is sensitive to poly(ADP-ribose) polymerase-1 gene deletion. (2003) (7)
- Pathophysiological aspects of cellular pyridine nucleotide metabolism: focus on the vascular endothelium. Review. (2003) (7)
- Detection of certain peroxynitrite-induced DNA modifications. (2002) (7)
- Cytoprotective and anti-inflammatory effects of hydrogen sulfide in macrophages and mice (2007) (7)
- 2-(N-acyl) and 2-N-acyl-N(6)-substituted analogues of adenosine and their affinity at the human adenosine receptors. (2004) (7)
- Combined Recombinant Human Activated Protein C and Ceftazidime Prevent the Onset of Acute Respiratory Distress Syndrome in Severe Sepsis (2012) (7)
- Differential vascular actions of ethanol in feline middle cerebral and mesenteric artery. (1991) (7)
- Role of Hydrogen Sulfide and 3-Mercaptopyruvate Sulfurtransferase in the Regulation of the Endoplasmic Reticulum Stress Response in Hepatocytes (2020) (7)
- Host cystathionine-γ lyase derived hydrogen sulfide protects against Pseudomonas aeruginosa sepsis (2021) (7)
- Prolonging hypothermic ischaemic cardiac and vascular storage by inhibiting the activation of the nuclear enzyme poly(adenosine diphosphate-ribose) polymerase (2017) (7)
- Poly (ADP-Ribose) Synthetase as a Novel Therapeutic Target for Circulatory Shock (2001) (7)
- The mitochondria‐targeted hydrogen sulfide donor AP39 improves health and mitochondrial function in a C. elegans primary mitochondrial disease model (2020) (7)
- Use of mono‐bromo‐bimane to derivatize sulfide in whole blood: comparison of blood sulfide levels during atmospheric hydrogen sulfide exposure and intravenous sulfide infusion (2008) (7)
- ACTIVATION OF POLY (ADP) RIBOSYL SYNTHETASE (PARS) MEDIATES CYTOTOXICITY INDUCED BY PEROXYNITRITE IN HUMAN INTESTINAL EPITHELIAL CELLS.: 193 (1996) (6)
- Poly(ADP-ribose) polymerase (PARP) activation is an early event in angiotensin-induced cardiovascular disorders (2003) (6)
- Mitochondrial respiration and cytochrome c inhibition by sulfide in peritoneal macrophages in vitro: effects of temperature and pH (2010) (6)
- H2S as a Therapeutic Adjuvant Against COVID-19: Why and How? (2021) (6)
- Suppression of experimental allergic encephalomyelitis by administration of 5-IODO-6-Amino-1,2,benzopyrone. A novel inhibitor of poly (ADP-ribose) synthetase (1998) (6)
- PP65 - Selectivity of hydrogen sulfide toward cyclic nucleotide phosphodiesterases (2015) (6)
- Poly(ADP-ribose) polymerase inhibition combined with irradiation: a dual treatment concept to prevent neointimal hyperplasia after endarterectomy. (2006) (6)
- Cytokines stimulate expression of inducible nitric oxide synthase in DLD-1 human adenocarcinoma cells by activating poly(A) polymerase (2004) (6)
- Short-time effects of glipizide, an ATP-sensitive potassium channel inhibitor, on cardiopulmonary hemodynamics and global oxygen transport in healthy and endotoxemic sheep: A-724 (2006) (6)
- Characterization of a neurogenic and a direct smooth muscle component in the contractile response to electrical field stimulation in rat tail artery. (1990) (6)
- Prevention of the hemorrhagic hypotension-induced hepatic arterial vasoconstriction by L-arginine and naloxone. (1999) (6)
- Role of Poly(ADP-ribose) Polymerase in Brain Inflammation and Neuroinjury (2008) (5)
- Diabetic endothelial dysfunction (2001) (5)
- ΔMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage (2021) (5)
- Poly(ADP-ribose) polymerase inhibition reverses vascular dysfunction after gamma-irradiation. (2006) (5)
- Sequential Accumulation of ‘Driver’ Pathway Mutations Induces the Upregulation of Hydrogen-Sulfide-Producing Enzymes in Human Colonic Epithelial Cell Organoids (2022) (5)
- Intravenous hydrogen sulfide does not induce neuroprotection after aortic balloon occlusion-induced spinal cord ischemia/reperfusion injury in a human-like porcine model of ubiquitous arteriosclerosis (2018) (5)
- Nebulized nitric oxide/nucleophile adduct reduces pulmonary vascular resistance in mechanically ventilated septicemic sheep* (2005) (5)
- Repurposing of Clinically Approved Poly-(ADP-Ribose) Polymerase Inhibitors for the Therapy of Sepsis (2021) (5)
- 3-Mercaptopyruvate sulfurtransferase deficient mice show accelerated glucose uptake and a dysregulated metabolic profile (2015) (5)
- Cytoprotective effect of γ-tocopherol against tumor necrosis factor α induced cell dysfunction in L929 cells. (2011) (5)
- ARGININE VASOPRESSIN RECEPTOR 2 ACTIVATION PROMOTES MICROVASCULAR PERMEABILITY IN SEPSIS. (2020) (5)
- Proinflammatory cytokines depress cardiac efficiency by a nitric oxide-dependent mechanism. (1998) (5)
- Changes of contractile and endothelium-dependent relaxant responses following a 2-H hemorrhagic hypotension in cats: Regional differences (1991) (5)
- Role of endothelium in the response of the vein wall to magnesium withdrawal (1992) (4)
- Regulation of CyR61 expression and release by 3-mercaptopyruvate sulfurtransferase in colon cancer cells (2022) (4)
- Maturation-dependent sequential expression of interferon regulatory factor-1 and inducible nitric oxide synthase in cultured human enterocytes. (2000) (4)
- Glutamate Excitotoxicity Induced by Nitric Oxide Mediated Dysfunction of the Mitochondrial 2-Oxoglutarate Dehydrogenase Complex (2017) (4)
- Noradrenaline induces rhythmic contractions of feline middle cerebral artery at low extracellular magnesium concentration. (1990) (4)
- Quantification of PARP activity in human tissues: ex vivo assays in blood cells and immunohistochemistry in human biopsies. (2011) (4)
- Inhibition of the 3-mercaptopyruvate sulfurtransferase—hydrogen sulfide system promotes cellular lipid accumulation (2022) (4)
- Oxidative-Nitrative Stress and Poly (ADP-Ribose) Polymerase Activation 3 Years after Pregnancy (2018) (4)
- Opposite effects of vascular irradiation on inflammatory response and apoptosis induction in the vessel wall layers via the peroxynitrite-poly(ADP-ribose) polymerase pathway (2006) (4)
- Peroxynitrite: Biochemistry, toxicology and development of therapeutics (2009) (4)
- Role of poly(ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and diabetic vascular dysfunction (2002) (4)
- Erratum: Disruption of the actin cytoskeleton results in nuclear factor-κB activation and inflammatory mediator production in cultured human intestinal epithelial cells (Journal of Cellular Physiology (2004) (71-81) DOI:10.1002/jcp.10477) (2004) (4)
- Intravenous β-endorphin administration fails to alter hypothalamic blood flow in rats expressing normal or reduced nitric oxide synthase activity (1996) (4)
- Poly-ADP-ribose polymerase inhibition reduces mesenteric injury after cardiopulmonary bypass. (2004) (4)
- Meta-analysis of gene expression patterns in Down syndrome highlights significant alterations in mitochondrial and bioenergetic pathways. (2021) (4)
- Graft derived cells with double nuclei in the penumbral region of experimental brain trauma (2006) (3)
- 233 NON-ARGININE BASED, SELECTIVE INHIBITORS OF INDUCIBLE NO SYNTHASE EXERT BENEFICIAL EFFECTS IN ENDOTOXIC SHOCK (1995) (3)
- Role of Nitric Oxide in the Development of Vascular Contractile Dysfunction in Circulatory Shock (2011) (3)
- Interplay of superoxide, nitric oxide and peroxynitrite in doxorubicin‐induced cell death (2008) (3)
- OP21 Role of phosphodiesterase inhibition and modulation of mitochondrial cAMP levels in the bioenergetic effect of hydrogen sulfide in isolated mitochondria (2013) (3)
- Inhibition of poly (ADP-ribose) synthetase prevents the neurological development of experimental allergic encephalomyelitis (1998) (3)
- Adenosine receptor agonists inhibit Macrophage Inflammatory Protein (MIP)-1α production in immunostimulated macrophages (1998) (3)
- Regional differences in the contractile activity of neuropeptide Y, endothelin, oxytocin and vasopressin: comparison with non-peptidergic constrictors. An in vitro study in the basilar and mesenteric arteries of the rat. (1992) (3)
- Human internal thoracic artery grafts exhibit severe morphological and functional damage and spasmic vasomotion due to oxidative stress (2011) (3)
- P19 Cysthionine-β-synthetase inhibition in combination with standard-chemotherapy decreases colorectal cancer metastasis to the liver (2014) (3)
- Time-dependent effects of intravenous H2S during long-term, resuscitated porcine hemorrhagic shock (2010) (3)
- H2S and cancer: Give credit where credit is due. (2016) (3)
- Cytopathic Hypoxia in Circulatory Shock: The Role of Poly (ADP-Ribose) Synthetase Activation (2002) (3)
- H2S biogenesis by cystathionine beta-synthase: mechanism of inhibition by aminooxyacetic acid and unexpected role of serine (2022) (3)
- Effects of the PARP Inhibitor Olaparib on the Response of Human Peripheral Blood Leukocytes to Bacterial Challenge or Oxidative Stress (2022) (3)
- Inhibitors of Nitric Oxide Biosynthesis (1999) (3)
- The Physiology and Pathophysiology of Nitric Oxide in the Lung (1997) (3)
- Anti-inflammatory and cytoprotective effects of inosine (2006) (3)
- Role of Calcium in Contractile and Endothelium-Dependent Dilatory Responses of Cerebral, Mesenteric and Coronary Arteries (1990) (3)
- The effects of therapeutic sulfide on myocardial apoptosis in response to ischemia—reperfusion injury § , (2011) (3)
- Role of interleukin-10 in the suppression of the immunological response in mice exposed to staphylococcal enterotoxin (1998) (2)
- Role of the cystathionine β-synthase / H2S pathway in the development of cellular metabolic dysfunction and pseudohypoxia in down syndrome (2022) (2)
- Nitric oxide and sepsis. (1996) (2)
- P20: Pro- and anti-proliferative effects of hydrogen sulfide in colon cancer cells: A unifying hypothesis (2014) (2)
- POLY-ADP-RIBOSYLATION AS A POST-TRANSLATIONAL MODIFICATION OF MITOCHONDRIAL PROTEINS: 82 (2004) (2)
- Faculty Opinions recommendation of Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis. (2013) (2)
- Effects of temperature and H2S inhalation on glucose metabolism in murine resuscitated septic shock (2010) (2)
- [The role of nitric oxide synthase, and of granulocytes, in endotoxin-induced early myocardial depression]. (2000) (2)
- Cytoglobin Silencing Promotes Melanoma Malignancy but Sensitizes for Ferroptosis and Pyroptosis Therapy Response (2022) (2)
- Simultaneous targeting or multiple pathways of shock: how promising, how novel? (1999) (2)
- Poly(ADP-ribose) activation in circulating cells in human myocardial infarction. (2009) (2)
- MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity (2022) (2)
- POLY (ADP‐RIBOSE) SYNTHETASE ACTIVATION INDUCED BY PEROXYNITRITE MEDIATES MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY: 351 (1997) (2)
- Effect of intravenous H2S on porcine aortic occlusion-induced systemic inflammation and kidney ischemia/reperfusion injury (2010) (2)
- Early Diabetes-Induced Changes in the Retina: Comparison of STZ Models in Rat and Mouse (2003) (2)
- Inflammatory disease and sunlight: the vitamin D-poly (ADP-ribose) polymerase connection (2008) (2)
- Hydrogen sulfide-induced S-sulfhydration of ATP synthase stimulates mitochondrial bioenergetics (2015) (2)
- MODULATION OF CYTOKINE AND NITRIC OXIDE PRODUCTION BY ADRENERGIC, DOPAMINERGIC AND ADENOSINE RECEPTOR LIGANDS IN ENDOTOXEMIA: 106 (1997) (2)
- The E3-Ubiquitin Ligase Ring Finger Protein 146 (RNF146) Regulates Cardiomyocyte Injury during Oxidative Stress (2014) (2)
- 864 Inhibition of poly(ADP-ribose) polymerase (PARP) protects mice from cholestatic liver injury (2003) (2)
- Hydrogen sulfide: anti-inflammatory and cytoprotective effects (2009) (2)
- Influence of extracellular magnesium on the contractile and endothelium-dependent dilatory responses of feline mesenteric arteries. (1991) (2)
- Free radical scavenging as a therapeutic strategy for bacteremia. (2005) (2)
- Hydrogen sulfide in lung adenocarcinoma: A tumor cell survival factor, an enhancer of mitochondrial DNA repair and a cellular bioenergetic stimulator (2015) (2)
- Mercaptoethylguanidine, an inhibitor of nitric oxide synthase, and a scavenger of peroxynitrite exerts beneficial effects in hemorrhagic shock (1997) (2)
- POLY (ADP‐RIBOSE) SYNTHETASE MEDIATES NEUTROPHIL SEQUESTRATION AND LIPID PEROXIDATION AFTER MESENTERIC ISCHEMIA.: 188 (1998) (2)
- Epigallocatechin gallate is a potent inhibitor of cystathionine beta-synthase: Structure-activity relationship and mechanism of action. (2022) (2)
- Effects of parenteral alanyl-glutamine dipeptide pretreatments on the ischemia-reperfusion injury of the liver in rats (2009) (2)
- Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis (2022) (2)
- OP17 Cystathionine-β-synthase (CBS) is upregulated in colorectal cancer cells and promotes their proliferation (2013) (2)
- Perspectives of the livestock sector in the Philippines: A review (2021) (2)
- INHIBITION OF THE Na+/H+ ANTIPORTER SUPPRESSES IL‐12 PRODUCTION BY MOUSE MACROPHAGES.: 68 (2001) (2)
- Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Inflammation and Circulatory Shock (2006) (2)
- Local and systemic inflammation: role of poly (ADP-ribose) synthetase activation by reactive nitrogen species (2001) (2)
- P23 The angiogenic and vasorelaxant effect of H2S require the endogenous production of NO, while the angiogenic and vasorelaxant effect of NO require the endogenous production of H2S (2012) (2)
- Distinguishing endogenous and exogenous sulfide by mass spectroscopy (2008) (2)
- To the Editor: (2020) (2)
- NF B 1 ( p 50 )-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes (2002) (2)
- Effect of L-arginine on adrenal and renal blood flows during hemorrhage in cats. (1998) (2)
- ANTI‐INFLAMMATORY PROFILE OF DANTROLENE: INHIBITION OF ENDOTOXIN‐INDUCED TUMOR NECROSIS FACTOR AND ENHANCEMENT OF INTERLEUKIN ‐ 10 PRODUCTION, BUT NO EFFECT ON NITRIC OXIDE AND INTERLEUKIN‐6 PRODUCTION.: 145 (1996) (2)
- Epalrestat induces cell proliferation and migration in endothelial cells via mTOR activation through PI3/Akt signaling (2014) (2)
- Poly (ADP-ribose) synthetase modulates expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia-reperfusion injury (1998) (1)
- PARP inhibition is therapeutic in CNS inflammation through immunomodulation (2003) (1)
- 2-aminopyridines: Novel inhibitors of nitric oxide synthases with potent pressor effects (1996) (1)
- EFFECTS OF THE PARP INHIBITOR PJ34 DURING PORCINE ENDOTOXEMIA.: 29 (2002) (1)
- Regulation of monocyte/macrophage function by adenosine receptors (2006) (1)
- Poly(ADP-Ribose)synthetase activation and NAD depletion after traumatic brain injury in rats (1999) (1)
- Role of poly(ADP-ribose) polymerase activation in the pathogenesis of shock and inflammation (2002) (1)
- Melatonin inhibits the expression of the inducible isoform of nitric oxide synthase and exerts protective effects in a carrageenan-induced model of inflammation (1998) (1)
- Peroxynitrite: The Dark Side of Nitric Oxide-Effects of Mercaptoethylguanidine, a Combined Inhibitor of Inducible Nitric Oxide Synthase and Scavenger of Peroxynitrite, in Shock, Inflammation, and Ischemia-Reperfusion Injury (1999) (1)
- Erratum to "Toxicological and pathophysiological roles of reactive oxygen and nitrogen species" [Toxicology 276 (2010) 85-94] (2011) (1)
- P35 Cystathionine-β-synthase (CBS)-derived hydrogen sulfide (H2S) supports cellular bioenergetics in colon cancer cells in vitro (2013) (1)
- ROLE OF POLY (ADP‐RIBOSE) SYNTHETASE IN SPLANCHNIC ARTERY OCCLUSION SHOCK IN THE RAT: 131 (1997) (1)
- Aldose Reductase Inhibitor Fidarestat Alleviates Diabetes–Induced Retinal Oxidative–Nitrosative Stress and Poly(ADP–Ribose) Polymerase Activation (2005) (1)
- Corrigendum: Protective effects of mercoptoethylguanidine, a selective inhibitor of inducible nitric oxide synthase, in ligature-induced periodontitis in the rat (Journal of Pharmacology (1998) 123 (353-360)) (1998) (1)
- STIMULATION OF β-ADRENOCEPTORS INHIBITS ENDOTOXIN-INDUCED IL-12 AND MIP-1α PRODUCTION IN MICE.: 95 (1998) (1)
- NITRIC OXIDE, PEROXYNITRITE AND POLY(ADP‐RIBOSE) SYNTHETASE IN ANAPHYLACTIC SHOCK (1997) (1)
- Hydrogen Sulfide, an Emerging Regulator of Acid-Sensing Ion Channels (2021) (1)
- EFFECTS OF MERCAPTOETHYLGUANIDINE, A SELECTIVE INHIBITOR OF THE INDUCIBLE ISOFORM OF NITRIC OXIDE SYNTHASE, IN ENDOTOXIC SHOCK, HEMORRHAGIC SHOCK AND POLYMICROBIAL SEPSIS: 268 (1997) (1)
- Effects of nitric oxide synthase inhibition on the hemodynamic changes in hyperdynamic endotoxemia. (1997) (1)
- Oxidatively Damaged Mitochondrial DNA Induces Inflammation in Lung Epithelial Cells (2017) (1)
- PEROXYNITRITE IS INVOLVED IN THE PATHOGENESIS OF THE VASCULAR CONTRACTILE AND ENERGETIC FAILURE IN ENDOTOXIC SHOCK: 208 (1996) (1)
- A NOVEL METHOD FOR QUANTIFICATION OF POLY(ADPRIBOSE)-MODIFIED PROTEINS VALIDATED IN CEREBROSPINAL FLUID FROM INFANTS AND CHILDREN AFTER TRAUMATIC BRAIN INJURY.: 29 (2005) (1)
- INTERFERON‐GAMMA PRIMES CULTURED HUMAN INTESTINAL EPITHELIAL CELLS FOR INDUCTION OF NITRIC OXIDE SYNTHASE BY LIPOPOLYSACCHARIDE OR LIVE BACTERIA.: 75 (1996) (1)
- Correction: Intraluminal Flagellin Differentially Contributes to Gut Dysbiosis and Systemic Inflammation following Burn Injury (2017) (1)
- Abstract 4791: Cystathionine-β-Synthase (CBS) and the progression of colorectal carcinogenesis (2017) (1)
- P16 Hydrogen sulfide stimulates colorectal cancer-associated fibroblast proliferation and migration (2014) (1)
- Novel mitochondria-targeted hydrogen sulfide (H2S) donors stimulate cellular bioenergetics and protect endothelial cells from oxidative stress-induced injury and mitochondrial DNA damage. (2014) (1)
- PP78 - The biological effects of 3-mercaptopyruvate include vasodilatation, hypotension, stimulation of angiogenesis and stimulation of cellular bioenergetics: Relative contribution of enzymatic versus non-enzymatic hydrogen sulfide production (2015) (1)
- EVIDENCE FOR THE EXPRESSION OF THE INDUCIBLE NITRIC OXIDE SYNTHASE IN PERIODONTITIS : PROTECTIVE EFFECTS OF MERCAPTOETHYLGUANIDINE, A SELECTIVE INHIBITOR OF THE INDUCIBLE NITRIC OXIDE SYNTHASE (1997) (1)
- TRANSCRIPTIONAL REGULATION OF THE HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE GENE IN A COLONIC EPITHELIAL CELL LINE.: 195 (1996) (1)
- Inosine Protects Against Both the Primary Disease and Rejection of Syngeneic Islet Grafts in NOD Mice (2002) (1)
- BLOCKADE OF α2-ADRENOCEPTORS INHIBITS ENDOTOXIN-INDUCED IL-12 AND MIP-1α PRODUCTION IN MICE.: 108 (1998) (1)
- Peroxynitrite and nitrosative stress in heart failure: Role of matrix metalloproteinases (MMPs) and poly(ADP)-ribose polymerase (PARP) (2007) (1)
- Selective poly(ADP-ribose)-polymerase inhibition affects neither DNA repair nor cell senescence after ischemia-reperfusion (2005) (1)
- Myocardial Ischemia-reperfusion Injury: Role of the Peroxynitrite-poly(ADP-ribose) Polymerase Pathway (2002) (1)
- PP38 – Role of hydrogen sulfide in the endotoxemia and tolerance to lipopolysaccharide (2015) (1)
- CHARACTERIZATION OF THE INDUCTION AND ACTIVITY OF THE HUMAN INTESTINAL EPITHELIAL NITRIC OXIDE SYNTHASE.: 40 (1995) (1)
- ROLE OF POLY‐ADP RIBOSYL SYNTHETASE IN THE ENERGETIC AND FUNCTIONAL INJURY OF PULMONARY EPITHELIAL CELLS EXPOSED TO PEROXYNITRITE IN VITRO.: 203 (1996) (1)
- PP82 – Systemic infection and combined burn and infection: Contribution of host-derived and bacteria-derived hydrogen sulfide production to bacterial clearance (2015) (1)
- Abstract 2980: Cystathionine-beta-synthase (CBS)-derived hydrogen sulfide (H2S) supports proliferation, migration and bioenergetics in colon cancer-associated fibroblasts (CAFs) (2017) (1)
- Effects of neuronal nitric oxide synthase in ovine lung injury (2007) (1)
- [The severity of gestational diabetes mellitus affects microvascular dysfunction measured three years after pregnancy that may be related to increased oxidative stress]. (2015) (1)
- Nitric oxide synthases (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (1)
- Effect of inhibition of poly (AOP-ribose) synthetase on peroxynitrrte-induced thymocyte apoptosis (1998) (1)
- PP75 - AP39, a mitochondrially targeted hydrogen sulfide donor, exerts protective effects in a rat model of renal ischemia–reperfusion (2015) (1)
- OP22 – Gasotransmitters in cancer (2015) (1)
- POLY(ADP‐RIBOSE) POLYMERASE IS A REGULATOR OF CHEMOKINE PRODUCTION: RELEVANCE FOR THE PATHOGENESIS OF SHOCK AND INFLAMMATION.: 50 (2002) (1)
- Tu1975 H2S Inhibition of Cystathionine-β-Synthase (CBS) Using Novel Prodrug Decreases Colorectal Cancer Xenograft Growth With Less Toxicity Than Aminooxyacetic Acid (AOAA) (2015) (1)
- AQX-1125, A SHIP1 Activator In Clinical Development For Pulmonary Inflammation: Pharmacokinetics, Metabolism And Tolerability In Healthy Humans Volunteers (2012) (1)
- Bioequivalence between inhaled hydrogen sulfide and intravenously administered sodium sulfide (2008) (1)
- Analyses of heavy metals in attic dust of a former industrial city (Ózd, Hungary) (2021) (1)
- Comparison of two colorimetric antioxidant capacity assessment methods in bovine semen fractions. (2016) (1)
- Detection of exhaled sulfide gas: a potential in vivo, continuous monitoring technique for therapeutic sulfide donor compounds (2008) (1)
- Nitric oxide (NO) increases expression of vascular endothelium growth factor (VEGF) in cultured cells (1996) (1)
- Effect of a selective adenosine 3 receptor agonist on chemokine, cytokine and nitric oxide production in immunosttmulated macrophages and fibroblasts (1998) (0)
- Partial selectivity theoretical approximation of nitric oxide synthase (NOS) isoenzyme sulfur-based inhibitors (1998) (0)
- A rat model of glycaemic variability. Reply to Zaccardi F, Pitocco D, Ghirlanda G [letter] (2009) (0)
- Pyrazole-1- Carboxamidine and related compounds and novel inhibitors of nitric oxide synthase: Pharmacological characterization in cultured cells and vascular rings (1997) (0)
- P08 Cystathionine-β-synthase (CBS)-derived hydrogen sulfide (H2S) supports colorectal tumor growth and angiogenesis in vivo (2013) (0)
- Inhibition of neuronal nitric oxide syhnthase with 7-nitroindazole attenuates oxidative stress after combined burn and smoke injury in sheep: 4AP8-9 (2007) (0)
- Molecular Mechanisms of the Nitric Oxide Induced Vessel Wall Dysfunction in Sepsis (1998) (0)
- Substituted indeno-ä1,2 cue isoquinoline derivatives and uses it (2002) (0)
- Pro‐tumorigenic Effects of Hydrogen Sulfide (H2S) on Normal Colonic Fibroblasts (NCF) and Colorectal (CRC) Cancer‐Associated Fibroblasts (CAF) (2015) (0)
- Contractile dysfunction in experimental cardiac allograft rejection: role of the poly (ADP-ribose) polymerase pathway (2006) (0)
- NITRIC OXIDE SENSITIVITY OF THE ACONITASES (1997) (0)
- ROLE OF POLY (ADP‐RIBOSE) SYNTHETASE (PARS) ACTIVATION IN THE ALTERATIONS IN MITOCHONDRIAL FUNCTION IN PEROXYNITRITE TREATED CELLS.: 40 (1998) (0)
- ANTI‐INFLAMMATORY EFFECTS OF VERAPAMIL AND DILTIAZEM IN ENDOTOXIN‐TREATED MICE: 366 (1997) (0)
- inhalation injury peroxynitrite decomposition catalyst in burn and smoke Beneficial pulmonary effects of a metalloporphyrinic (2011) (0)
- ROLE OF POLY‐ADP RIBOSYL SYNTHETASE IN THE PATHOGENESIS OF THE VASCULAR CONTRACTILE AND ENERGETIC FAILURE IN RODENT ENDOTOXIN SHOCK: 210 (1996) (0)
- P31 Sulfide metabolism at low oxygen conditions (2012) (0)
- Screening of Heteroaromatic Scaffolds against Cystathionine Beta-Synthase Enables Identification of Substituted Pyrazolo[3,4-c]Pyridines as Potent and Selective Orthosteric Inhibitors (2020) (0)
- P21: Cytoprotective effects of AP39, a mitochondrially targeted hydrogen sulfide donor in oxidatively stressed endothelial cells: Protection against the loss of cell viability and bioenergetics and attenuation of mitochondrial DNA injury (2014) (0)
- Recombinant human activated protein C reduces cardiac 3-nitrotyrosine and malondialdehyde levels in ovine acute respiratory distress syndrome and septic shock (2009) (0)
- burn and smoke inhalation injury in sheep Role of L-selectin in physiological manifestations after (2013) (0)
- Role of hydrogen sulfide in respiratory syncytial virus infection (2015) (0)
- IS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITION BENIFICIAL IN NON-CONTROLED HEMORRHAGIC SHOCK?: 161 (1999) (0)
- Therapeutic potential of PARP inhibitors in inflammatory dermatosis (2003) (0)
- Agents inhibiteurs d'inflammation et de lesion par perfusions repetees ; methode d'utilisation (2001) (0)
- Regulation of peroxynitrite-induced thymocyte apoptosis by poly(ADP-ribose) synthetase (PARS) (1998) (0)
- receptor agonists purine derivatives as adenosine A 1 and application procedures for (2005) (0)
- Angiotensin Converting Enzyme Inhibitor Treatment Influences Cardiopulmonary Function In Ovine Acute Lung Injury (2011) (0)
- Combined RhAPC and Ceftazidime reduces cardiac 3-nitrotyrosine levels in septic shock (2011) (0)
- 115 – High Glucose Exposure Induces a Compensatory Up-Regulation of Mitochondrial Function, Resulting in Cellular Resistance to Oxidative Stress in Human Endothelial Cells (2014) (0)
- Hydrogen sulfide modulates chromatin remodeling and inflammatory mediator production in response to endotoxin, but does not play a role in the development of endotoxin tolerance (2016) (0)
- Role of nitric oxide in hemorrhagic shock (1996) (0)
- MATURATION OF INTESTINAL EPITHELIAL CELLS REGULATES THE a OF HUMAN iNOS EXPRESSION (1997) (0)
- 557: FP15, a novel peroxynitrite decomposition catalyst reduces reperfusion injury in a rat heart transplantation model (2007) (0)
- Dantrolene inhibits IL-12, TNF-α, and nitric oxide production, but increases the formation of IL-10 in endotoxemic mice (1997) (0)
- The hydrogen sulfide donor IK‐1001 improves the outcome of acute respiratory distress syndrome in murine and ovine models (2008) (0)
- 11: EFFECTS OF 3-AMINOBENZAMIDE, AN INHIBITOR OF POLY (ADP-RIBOSE) SYNTHETASE, ON HEMODYNAMICS AND SURVIVAL IN A PORCINE MODEL OF HEMORRHAGIC SHOCK (1998) (0)
- Gaso-Transmitters Vascular biology of hydrogen sulfide (2017) (0)
- Effects of phosphodiesterase inhibitors rolipram and amrinone on IL-12, IFN-γ, IL-1, and nitric oxide production in endotoxemic mice: Relationship to production of IL-10 (1997) (0)
- BENEFICIAL EFFECTS OF GUANIDINO‐ETHYL‐DISULFIDE (GED), A NOVEL NITRIC OXIDE SYNTHASE INHIBITOR IN RODENT MODELS OF ENDOTOXIN SHOCK.: 205 (1996) (0)
- PL12 Molecular mechanisms and therapeutic implications of the pro-angiogenic effect of hydrogen sulfide (2013) (0)
- 80 - Posthypoxic Bioenergetic Recovery Requires Nicotinamide Adenine Dinucleotide (NAD+) Salvage in Cardiomyocytes (2014) (0)
- Peroxynitrite-induced toxicity in spinal cord neurons is dependent on poly(ADP-ribose) polymerase activation (2003) (0)
- Hypertonic saline solution (7,5% NaCl) in Acute Pancreatitis: the effect in hepatic expression of MMPs, HSPs and oxidative stress (2008) (0)
- 162 - Mitochondrial PARP1 Negatively Regulates Mitochondrial DNA Repair and Biogenesis ensitizing Cells to Oxidative Stress (2014) (0)
- Aminoethylisoselenourea and related compounds are potent inhibition of the inducible isoform of nitric oxide synthase in vitro and in vivo (1996) (0)
- REGULATION OF MACROPHAGE INFLAMMATORY PROTEIN (MIP)‐l&agr; PRODUCTION IN IMMUNOSTIMULATED MACROPHAGES BY MODULATION OF ADRENERGIC AND PURINERGIC RECEPTORS.: 74 (1998) (0)
- 140 - Hydrogen Sulfide Decreases Cytokine Production by Modulation of Histone Deacetylase and Chromatin Remodeling (2014) (0)
- Protective Role of Hydrogen Sulfide in Paramyxovirus Infection (2015) (0)
- Potent novel peroxynitrite decomposition catalyst FP15 improves ageing-associated cardiac and vascular dysfunction (2006) (0)
- Stable pharmaceutical compositions comprising desloratadine (2004) (0)
- Poly(ADP-ribose) polymerase inhibition: past, present and future (2020) (0)
- 37: INTRACELLULAR CALCIUM MOBILIZATION IS REQUIRED FOR PEROXYNITRITE-INDUCED POLY(ADP-RIBOSE) SYNTHASE ACTIVATION AND CYTOTOXICITY (1998) (0)
- Contribution of poly(ADP‐ribose) polymerase (PARP) to post‐ischemic blood‐brain barrier (BBB) damage in rats (2006) (0)
- Inhibition of poly (ADP) ribose synthetase ameliorates experimental obliterative bronchiolitis in rat tracheal allografts (2003) (0)
- 2-(N-Acyl) and 2-N-Acyl-N6-substituted Analogues of Adenosine and Their Affinity at the Human Adenosine Receptor. (2004) (0)
- Biopesticides the sustainable way of organic and healthy tomato production (2020) (0)
- Insulin therapy inhibits poly(ADP-ribose)polymerase activation in endotoxin shock (2007) (0)
- Poly(ADP-ribose) polymerase activation and the pathogenesis of circulatory shock (2000) (0)
- Transcriptional Regulation of the Human Inducible Nitric Oxide Synthase Gene in an Intestinal Epithelial Cell Line † 127 (1997) (0)
- Aztreonam L-lysine and process for its production (2004) (0)
- Editorial Note on the Special Issue: Chemistry, biology and clinical applications of the third gasotransmitter, hydrogen sulfide (H2S) (2021) (0)
- Effect of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, on the expression of P-selecitn and intercellular adhesion molecule-1 in myocardialischemia-reperfusion (1998) (0)
- Hydrogen Sulfide: A Metabolic Modulator and a Protective Agent in Animal Models of Reperfusion Injury (2009) (0)
- Poly (ADP-ribose) polymerase inhibition improves safe cardiac preservation times and cardiac function during heart transplantation (2006) (0)
- WW-85 IMPROVES CARDIOVASCULAR FUNCTIONS AND MICROCIRCULATION IN OVINE SEPTIC SHOCK (2006) (0)
- Inhibition of poly (ADP-Ribose) polymerase improves endothelial and myocardial function after brain death (2007) (0)
- Novel Role of Cathepsin V in TLR4 Mediated Signaling (2014) (0)
- Damaged Mitochondrial DNA as a Potent Inducer of Lung Inflammation (2016) (0)
- BLOCKADE OF POTASSIUM‐ATP CHANNELS INCREASES SURVIVAL AND IMPROVES HEMODYNAMIC AND METABOLIC PARAMETERS IN HEMORRHAGIC SHOCK.: 58 (1996) (0)
- 139 - Upregulation of Intracellular Hemoglobin in Peripheral Blood Mononuclear Cells during Burn Injury Serves as an Antioxidant and Cytoprotectant (2014) (0)
- 26 – Development and Optimization of a Stretch-Induced Neurotrauma Model for Medium-Throughput Screening (2014) (0)
- P17 Modulatory effect of S-adenyl-methionine, an allosteric activator of cystathionine-beta-synthase on the proliferation and bioenergetics of colon cancer cells: Mechanism of action (2014) (0)
- NITRIC OXIDE AND PEROXYNITRITE MEDIATED ACTIVATION OF POLY-ADF RIBOSYL SYNTHETASE CAUSES DEPLETION OF CELLULAR ENERGY STORES ??? A NOVEL PATHWAY IN THE PATHOGENESIS OF CIRCULATORY SHOCK (1995) (0)
- Basal poly-ADP ribosyl synthetase activity is involved in the regulation of the expression of the indicible isoform of ntric oxide synthase in cultured macrophages and conscious rats (1996) (0)
- PEROXYNITRITE FORMATION AND ACTIVATION OF POLY (ADP‐RIBOSE) SYNTHETASE IN SPINAL CORD TRAUMA: 19 (1998) (0)
- 215 - Hydrogen Sulfide Is an Endogenous Stimulator of Mitochondrial DNA Repair (2014) (0)
- The cystathionine gamma-lyase/hydrogen sulfide pathway is involved in pathological retinal neovascularization in ischemic retinopathy (2015) (0)
- Single dose treatment with PARP-inhibitor INO-1001 improves cardiovascular dysfunction associated with advanced aging (2007) (0)
- Efficacy of Clinically Used PARP Inhibitors in a Murine Model of Acute Lung Injury (2022) (0)
- The Role of CD73 in the Generation of Extracellular Adenosine for Adenosine Receptor Signaling (2006) (0)
- 151 - Hydrogen Sulfide: A Supporter of Mitochondrial DNA Repair and Cellular Bioenergetics in Lung CancerCells (2015) (0)
- PROGESTERONE REGULATES INDUCIBLE NITRIC OXIDE SYNTHASE mRNA EXPRESSION IN HUMAN INTESTINAL EPITHELIAL CELLS AT A POST‐TRANSCRIPTIONAL LEVEL.: 70 (1998) (0)
- S6.4 Mechanisms of increased mitochondrial ROS generation in sepsis: The impact of AIF and delta Ψ (2008) (0)
- Rapid Communication ACTIVATION OF POLY(ADP-RIBOSE) POLYMERASE IN CIRCULATING LEUKOCYTES DURING MYOCARDIAL INFARCTION (2018) (0)
- Effect of ibuprofen on thermal injury with smoke inhalation (1997) (0)
- P32 Effect of co-morbidity on kidney expression of H2S-producing enzymes during porcine I/R injury (2013) (0)
- P35 Exacerbation of the septic response in cystathionine-gamma-lyase deficient mice (2014) (0)
- 337 - Glucocorticoids Decrease the Glucose-Induced Mitochondrial Reactive Oxygen Species (ROS) Production via Uncoupling Protein 2 (UCP2) Induction (2014) (0)
- Editor's note regarding "protective mechanisms of a metalloporhyrinic peroxynitrite decomposition catalyst, WW85, in rat cardiac transplants" (2006) (0)
- Effects of mercaptoethylguanidine during long-term hyperdynamic porcine endotoxemia (2000) (0)
- Poly(ADP-Ribose) Polymerase Activation and Nitrosative Stress in the Development of Cardiovascular Disease in Diabetes (2005) (0)
- Tryptophan nitration physiologically regulates cardiac lactate dehydrogenase active site loop mobility and activity (2018) (0)
- The poly(ADP-ribose) polymerase inhibitor PJ-34 inhibits neovascularization and vascular endothelial growth factor signalling (2007) (0)
- Endogenous glutathione protects against the vascular failure in response to peroxynitrite and endotoxic shock (1997) (0)
- Abstract 4276: Cystathionine-β-synthase overexpression increases cell proliferation, migration, bioenergetics and tumorigenesis in a non-tumorigenic colorectal cancer (CRC) cell line (2016) (0)
- Title : Poly ( ADP-ribose ) polymerase-1 is a key mediator of liver inflammation and fibrosis (0)
- THE ROLE OF NITRIC OXIDE IN IGG IMMUNE COMPLEX-INDUCED LUNG INJURY IN RATS (1999) (0)
- Brain Histology and Immunohistochemistry After Resuscitation From Hemorrhagic Shock in Swine With Pre-Existing Atherosclerosis and Sodium Thiosulfate (Na2S2O3) Treatment (2022) (0)
- Non-arginine based nitric oxide synthase inhibitors are potent inhibitors of cyclooxygenase activity in J774 macrophages (1996) (0)
- Pravastatin sodium new form of (2004) (0)
- 346: Poly (ADP-ribose) polymerase inhibition prolongs safe cardiac preservation times and improves cardiac function after heart transplantation (2006) (0)
- The development of science is uninterrupted (2021) (0)
- INHIBITORS OF POLY‐ADP RIBOSYLTRANSFERASE (PARS) INHIBIT THE DECREASE IN CELL VIABILITY IN RESPONSE TO NO DONORS OR IN RESPONSE TO NO SYNTHASE INDUCTION IN THE VASCULAR SMOOTH MUSCLE.: 41 (1995) (0)
- Effect of lipopolysaccharide (LPS)‐induced endotoxemia in mice genetically deficient in either one of the three major hydrogen‐sulfide producing enzymes (2016) (0)
- Hydrogen sulfide for organ protection (2008) (0)
- Procedure for the preparation of the amorphy form of a pharmaco. (2005) (0)
- PL-03 - Role of hydrogen sulfide in critical illness (2016) (0)
- EFFECTS OF THE NITRIC OXIDE SYNTHASE INHIBITORS AMINOETHYL‐ISOTHIOUREA AND NG‐NITRO‐L‐ARGININE ON THE POSTISCHEMIC FLOW RESPONSE OF THE DOG INTESTINE.: 5 (1996) (0)
- INHALATION OF A NEBULIZED NO/NUCLEOPHILE ADDUCT PREFERENTIALLY REDUCES PULMONARY VASCULAR RESISTANCE IN AWAKE SEPTICEMIC SHEEP (1999) (0)
- Protection against ruggle by bioherbicides, herbicides and mechanical methods (2020) (0)
- INDUCTION OF NITRIC OXIDE PRODUCTION IN HUMAN EPITHELIAL CELLS INVOLVES TYROSINE PHOSPHORYLATION.: 199 (1998) (0)
- LPS induced a tissue‐dependent upregulation of some of the H2S‐producing enzymes in WT mice (upregulation of CBS in the spleen, upregulation of 3MST in the liver and upregulation (2016) (0)
- Activation of the peroxynitrite-poly (ADP-ribose) polymerase pathway during neointima proliferation: a new target to prevent restenosis after endarterectomy? (2006) (0)
- 357 - Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage (2013) (0)
- INO-1001, a novel poly(ADP-ribose) polymerase inhibitor reduces myocardial and endothelial reperfusion injury after orthotopic heart transplantation (2004) (0)
- STIMULATION OF &bgr;‐ADRENOCEPTORS INHIBITS ENDOTOXIN‐INDUCED IL‐12 AND MIP‐1&agr; PRODUCTION IN MICE.: 95 (1998) (0)
- P25 Exogenous and endogenous H2S stimulates mitochondrial electron transport and cellular bioenergetics in hepatocytes (2012) (0)
- Nitric oxide, peroxynitrite and poly (adpribose) synthetase activation: role in the suppression of cellular energetics (1997) (0)
- nitric oxide-dependent mechanism Proinflammatory cytokines depress cardiac efficiency by a (2016) (0)
- HEMODYNAMIC EFFECTS OF INHALED HYDROGEN SULFIDE DURING RESUSCITATED MURINE SEPTIC SHOCK (2009) (0)
- Role of peroxynitrite and poly-(ADP-ribose) synthetase in shock, inflammation, and ischemia-reperfusion injury (1999) (0)
- Nitrative signaling into cardiac lactate dehydrogenase Trp324 modulates active site loop mobility and activity under metabolic stress (2018) (0)
- 277 – Novel Mitochondria-Targeted Hydrogen Sulfide (H2S) Donors AP39 and AP123 Attenuate Hyperglycaemia-Induced Oxidative Stress and Loss of Bioenergetics in Microvascular Endothelial Cells (2014) (0)
- Poly (ADP-ribose) polymerase inhibition improves cardiac function during cardiac rejection (2005) (0)
- Haem oxygenase (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
- Gamma‐tocopherol nebulization attenuates acute lung injury with burn and smoke inhalation in the ovine model (2012) (0)
- Improvement of aging-associated cardiac and endothelial dysfunction by the copper (II) aspirinate complex (2009) (0)
- Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells (2018) (0)
- PEROXYN1TRITE‐DEPENDENT AND PEROXYNITRITE ‐ INDEPENDENT CYTOTOXIC MECHANISMS IN THE ABSENCE OF INDUCIBLE NITRIC OXIDE SYNTHASE.: 202 (1998) (0)
- NITRIC OXIDE AND SEPSIS. AUTHORS'S REPLY (1996) (0)
- 'Professor Galveston' has departed. Obituary - Daniel Traber (2012) (0)
- THE POLY (ADP‐RIBOSE) SYNTHETASE (PARS) PATHWAY AS A MEDIATOR OF METABOLIC ALTERATIONS IN SHOCK AND REPERFUSION INJURY.: 216 (1998) (0)
- EFFECT OF AMNIRONE ON CYTOKINE AND NITRIC OXIDE PRODUCTION IN IMMUNOSTIMULATED MACROPHAGES AND IN ENDOTOXEMIC MICE: 277 (1997) (0)
- for disulfide HMGB1– dependent TLR4 signaling (2015) (0)
- Transplanted stem cells undergo cellular fusion in experimental brain trauma (2005) (0)
- 275 – Development of Mitochondrial Dysfunction in a Murine Model of Burn Injury (2014) (0)
- PP76 – Aminooxyacetic acid, an inhibitor of cystathionine-β-synthase, exerts protective effects in a murine model of thermal injury (2015) (0)
- Procede de preparation de mycophenolate mofetil et d'autres esters d'acide mycophenolique (2005) (0)
- Introduction: Cell death by energy depletion: A reemerging concept via the nitric oxide connection (2000) (0)
- Amorhes simvastatin calcium and methods for production thereof (2004) (0)
- WW-85 IMPROVES PULMONARY FUNCTION IN OVINE SMOKE INHALATION INJURY AND SEPSIS (2006) (0)
- NITRIC OXIDE AND PEROXYNITRITE RELATED ANTI-INFLAMMATORY EFFECTS OF MELATONIN (1997) (0)
- Oxidation of mitochondrial and nuclear proteins by endogenously produced peroxynitrite in immunostimulated macrophages (1997) (0)
- 355 - Regulation of Mitochondrial Poly(ADP-Ribose) Polymerase Activation by the Beta-Adrenoceptor/CAMP / Protein Kinase Axis during Oxidative Stress (2014) (0)
- ENDOGENOUS INTERLEUKIN-10 ATTENUATES SPLANCHNIC ISCHEMIA-REPERFUSION INJURY IN MICE (1999) (0)
- 267 – Diabetes Impairs the 3-Mercaptopyruvate Sulfurtransferase / Hydrogen Sulfide Mediated Cellular Bioenergetic System: Protection by Alpha-Lipoic Acid (2014) (0)
- EFFECTS OF S‐METHYL‐ISOTHIOUREA ON THE MYOCARDIAL CONTRACTILITY AND THE HEMODYNAMIC CHANGES IN HYPERDYNAMIC ENDOTOXEMIA.: 192 (1996) (0)
- Tamás Transplantation Poly ( ADP-Ribose ) Polymerase Inhibition Reduces Reperfusion Injury After Heart (2001) (0)
- POLY(ADP‐RIBOSE) POLYMERASE: RELEVANCE FOR SHOCK AND INFLAMMATION: 358 (2004) (0)
- Hydrogen sulphide induces angiogenesis (2009) (0)
- Endotoxin-Induced Shock Mechanism and Protects Against Production by a Posttranscriptional Inosine Inhibits Inflammatory Cytokine (1999) (0)
- Mercaptoethylguanidine and related compounds are scavengers of peroxynitrite (1997) (0)
- Endogenous Inhibitors of the Induction of the Inducible Isoform of Nitric Oxide Synthase (1996) (0)
- A process for the recovery of statin compounds from a fermentation broth (2000) (0)
- A process for preparing 1,2,3,9-tetrahydro-9-methyl-3 - [(2-methyl-1H-imidazol-1-yl) methyl] -4H-carbazol-4-one (2003) (0)
- Efficacy of a novel SHIP1 activator in animals and healthy human volunteers exposed to inhaled lipopolysaccharide (2012) (0)
- BLOCKADE OF &agr;2‐ADRENOCEPTORS INHIBITS ENDOTOXIN‐INDUCED IL‐12 AND MIP‐1&agr; PRODUCTION IN MICE.: 108 (1998) (0)
- Poly-ADP-ribosylation is a prevalent post-translational modification of mitochondrial proteins in the brain (2005) (0)
- Ceftazidime reduces cardiac 3-nitrotyrosine and malondialdehyde levels in ovine ards and septic shock (2009) (0)
- S8-1 Pathophysiological changes in hyrogen sulfide homeostasis during diabetic complications (2014) (0)
- Editorial: Old dog, new tricks: proangiogenic effect of adenosine via stimulation of thrombospondin‐1 in macrophages (2015) (0)
- PP77 – Upregulation of hemoglobins in burn injury confers protection against hydrogen sulfide mediated cellular dysfunction (2015) (0)
- The phosphodtesterase m inhibitor amrinone modulates cytokjne and nttric oxide production in immunostimulated macrophages (1998) (0)
- 5‐AMINOSALICYLIC ACID (5‐ASA) INHIBITS INDUCIBLE NITRIC OXIDE SYNTHASE (iNOS) EXPRESSION IN HUMAN INTESTINAL EPITHELIAL CELLS.: 195 (1998) (0)
- Inhibition of PARP inhibits development of early stages of diabetic retinopathy (2004) (0)
- Mitokondriális eredetű nitrogén szabadgyökök és ATP-függő K-csatornák szerepe az organellum működésében = The involvement of mitochondrial-derived nitrogen radicals and mitoK-ATP channels in the regulation of organelle function (2009) (0)
- University of Groningen Overexpression of Cystathionine gamma-Lyase Suppresses Detrimental Effects of Spinocerebellar Ataxia Type 3 Snijder, (2016) (0)
- Poly(ADP-ribose) polymerase (PARP) in the pathogenesis of diabetic complications (2003) (0)
- Abstract 16315: Olaparib, a Clinically Used Poly(adp-ribose) Polymerase Inhibitor, Protects Against Oxidant-Induced Cardiac Myocyte Death in vitro and Improves Cardiac Contractility During Early Phase After Heart Transplantation in an in vivo Rat Model (2017) (0)
- endothelial reperfusion injury after hypothermic cardiac arrest Poly-ADP-ribose polymerase inhibition protects against myocardial and (2013) (0)
- Nitric oxide and sepsis (1996) (0)
- Circulating methemoglobin & nitrite/nitrate in children with septic shock (1996) (0)
- -Adrenoceptor/cAMP/Protein Kinase A Axis during Oxidative Stress (2015) (0)
- Oxidative Stress Induces an Early-Onset Mitochondrial Poly(ADP-Ribose) Polymerase Activation in U937 Cells (2014) (0)
- EFFECTS OF GLIPIZIDE (AN ATP-SENSITIVE POTASSIUM CHANNEL INHIBITOR) AND NOREPINEPHRINE ON HEMODYNAMICS AND GLOBAL OXYGEN TRANSPORT IN ENDOTOXEMIC SHEEP.: 159-T (2005) (0)
- production in the lung Adenovirus infection increases iNOS and peroxynitrite (2013) (0)
- 69 - Endothelial Dysfunction Is a Potential Contributor to Multiple Organ Failure and Mortality in Aged Mice Subjected to Septic Shock: Preclinical Studies in a Murine Model of Cecal Ligation and Puncture (2014) (0)
- THE EFFECT OF ecNOS INHIBITION ON INTESTINAL MICROCIRCULATION DURING HEMORRHAGIC SHOCK.: 209 (1996) (0)
- Role of poly(ADP-ribose) polymerase (PARP) activation in the pathogenesis of toxic liver injury (2003) (0)
- Role of Nitric Oxide on Cardiac Dysfunction After Massive Cutaneous Burn and Smoke Inhalation Combined Injury in Conscious Sheep: 140. (2000) (0)
- Facile and Convenient Syntheses of 6,11‐Dihydro‐5H‐indeno[1,2‐c]isoquinolin‐5‐ones and 6,11‐Dihydro‐5H‐indolo[3,2‐c]isoquinolin‐5‐one. (2005) (0)
- Role of Cystathionine β-Synthase and 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics of Murine Breast Cancer Cells (2023) (0)
- exchanger blockade inhibits enterocyte inflammatory response and protects against colitis (2002) (0)
- P22: Mitochondira-targeted hydrogen sulfide donors AP39 and AP123 attenuate hyperglycaemia-induced oxidative stress and loss of bioenergetics in microvascular endothelial cells (2014) (0)
- Poly(ADP-ribose) polymerase (PARP) and chronic heart failure (2003) (0)
- Tu2004 Increased Levels of Cystathionine-β-Synthase Arise From Cancer Stem-Like Cells in Colon Cancer (2015) (0)
- 254 - High-Glucose-Induced Reactive Oxygen Species (ROS) Generation Is Reduced by Microtubular Agents in Microvascular Endothelial Cells (2014) (0)
- ADHESION OF BACTERIAL PATHOGENS TO INTESTINAL EPITHELIAL CELLS IS A SUFFICIENT STIMULUS OF NF‐&kgr;B ACTIVATION.: 71 (1998) (0)
- INHIBITORY EFFECT OF ESTROGEN AND PROGESTERONE ON THE EXPRESSION AND ACTIVITY OF THE INDUCIBLE NITRIC OXIDE SYNTHASE IN HUMAN INTESTINAL EPITHELIAL CELL MONOLAYERS.: 202 (1996) (0)
- Incretin mimetics restore the ER-mitochondrial axis and switch neuronal fate towards survival. (2021) (0)
- Oxidant-Induced Cell Death Mediates Mitochondrial Injury During Poly(ADP-Ribose) Synthetase Activation (2017) (0)
- The effect of growing media on the nutritional value of cherry tomato (2020) (0)
- Regulation of Vascular Tone and Angiogenesis by the 3-Mercaptopyruvate Sulfur Transferase / Hydrogen Sulfide System under Physiological Conditions and during Diabetes (2014) (0)
- Inhibition of Poly (ADP‐ribose) Polymerase (PARP) by PJ‐34 regulates angiogenesis and VEGF‐induced MAPK‐signalling (2008) (0)
- Method for determination of impurities in a lysine salt of amorphous aztreonam. (2004) (0)
- Abstract 631: Complementary Roles for 3-mercaptopyruvate Sulfurtransferase and Cystathionine γ-lyase in Angiogenesis (2019) (0)
- Zolpidem Hemitartrate micronisé (2001) (0)
- Procedures for the preparation of polymorphic forms of desloratadine. (2004) (0)
- A process for preparing pimecrolimus (2005) (0)
- Investigation of the synergism of air pollution and ruggle pollene load (2020) (0)
- Structural characterization of an endoglucanase from Serpula lacrymans var. lacrymans S7.9 (2011) (0)
- Role of nitric oxide in circulatory shock. (1995) (0)
- 867-3 Peroxynitrite inactivates Akt pathway and enhances tissue factor expression in thrombin stimulated endothelial cells (2004) (0)
- Process for the recovery of compounds stanine from a fermentation broth. (2000) (0)
- A process for producing highly pure deferoxamine salts (1993) (0)
- A process for the preparation of 1,2,3,9-tetrahydro-9-methyl-3 - [(2-methyl-1H-imidazol-1-yl) methyl] -4H-carbazol-4-one (2003) (0)
- Inhibition of poly (ADP-nbose) synthetase ameliorates neutrophil recruitment in vivo (1998) (0)
- P98 Tetracyclin antibiotics as inhibitors of H2S synthesis (2014) (0)
- Zolpidem hemitartrate comme solvate (2001) (0)
- ABSENCE OF INDUCIBLE NITRIC OXIDE SYNTHASE REDUCES LETHALITY IN TNBSINDUCED COLITIS.: 134 (1998) (0)
- Procedure de preparation d'un medicament de forme amorphe (2005) (0)
- Erratum: Role of nitric oxide in vascular permeability after combined burns and smoke inhalation injury (American Journal of Respiratory and Critical Care Medicine (2001) 163 (745-752)) (2001) (0)
- BENEFICIAL EFFECTS OF MERCAPTOETHYLGUANIDINE IN A PORCINE MODEL OF HEMORRHAGIC SHOCK (1998) (0)
- Meta-analysis of metabolites involved in bioenergetic pathways reveals a pseudohypoxic state in Down syndrome (2020) (0)
- The hydrogen sulfide donor IK‐1001 protects against hepatic reperfusion injury in a murine model: evidence for a gender difference (2008) (0)
- Biomineralization and detoxification of toxic compounds, otavite production by Cupriavidus campinensis S14E4C (2021) (0)
- Novel Regulatory Roles of Hydrogen Sulfide in Health and Disease (2022) (0)
- Mycophenolate de sodium cristallin (2005) (0)
- S6-5 Role of cystathionine-beta synthase and its product, hydrogen sulfide in cancer biology (2014) (0)
- Abstract 3548: Hypoxia-induced Cystathionine-β-synthase (CBS) expression: impact on colonic epithelial cells metabolism, proliferation and migration (2017) (0)
- PL03 Expression of H2S-catalyzing enzymes during “acute chronic disease” (2013) (0)
- NO‐related hemodynamic effects of KATP channel blockade in canine endotoxic shock.: 116 (1996) (0)
- Hydrogen sulphide synthesis (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
- Poly (ADP-Ribose) Polymerase Inhibitor (PJ34) Inhibits Leukocyte Entrapment in the Retinal Microcirculation of Diabetic Rats (2003) (0)
- PP79 - Screening of a composite collection of clinically used drugs and well-annotated compounds for the inhibition of cystathionine-β-synthetase activity (2015) (0)
- Reply to Giamogante et al.: The effect of low cyanide on O2 consumption is best observed in physiological, rather than reductionist, systems (2021) (0)
- BENEFICIAL EFFECTS OF NITRIC OXIDE SYNTHASE INHIBITION IN SHOCK STATES.: 223 (1996) (0)
- Cell necrosis: A futile, unregulated process, or a novel drug development target? (2006) (0)
- Abstract 492: Circulating Hydrogen Sulfide is Stored as Labile Sulfurs in Albumin (2013) (0)
- HYPERTONICITY INDUCES NF‐&kgr;B ACTIVATION AND IL‐8 PRODUCTION IN HUMAN INTESTINAL EPITHELIAL CELLS.: 27 (2002) (0)
- Pharmacological inhibition, or genetic ablation of poly (ADPribose) synthetase exerts anti-inflammatory effects in a zymosan induced model of multiple organ failure (1998) (0)
- Inhaled nitric oxide in ARDS: is the question closed? (1999) (0)
- Abstract 1950: Role of Superoxide, Nitric Oxide and Peroxynitrite in Doxorubicin-induced Cell Death in vitro and in vivo (2007) (0)
- The of Ectonucleotidases ammation (2016) (0)
- 369 - Role of PARP1 in Oxidative Stress Resistance in the Context of Muscle Cell Differentiation (2014) (0)
- DEVELOPMENT OF ENDOTOXIN TOLERANCE BY RADIO‐DETOXIFIED ENDOTOXIN SUPPRESSES NITRIC OXIDE AND PROSTAGLANDIN SYNTHESIS.: 188 (1996) (0)
- A method for underground-purifying water pit (1984) (0)
- AQX-1125, A SHIP1 Activator, Inhibits Chemotaxis In Vitro And Exerts Pleiotropic Anti-Inflammatory Effects In A Rodent Model Of Endotoxin-Induced Pulmonary Inflammation (2012) (0)
- 141: Inhibition of poly (ADP-ribose) polymerase improves endothelial and myocardial function after brain death (2007) (0)
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