Cynthia E. Dunbar
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American hematologist and physician-scientist
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Why Is Cynthia E. Dunbar Influential?
(Suggest an Edit or Addition)According to Wikipedia, Cynthia Dunbar is an American scientist and hematologist at the National Heart Lung and Blood Institute , which is part of the National Institutes of Health . She is the Branch Chief of the Translational Stem Cell Biology Branch.
Cynthia E. Dunbar's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1 (2006) (1196)
- Gene therapy comes of age (2018) (769)
- Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer (1992) (537)
- MRI detection of single particles for cellular imaging. (2004) (506)
- Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation. (1995) (476)
- Serial Cardiac Magnetic Resonance Imaging of Injected Mesenchymal Stem Cells (2003) (467)
- Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction. (1996) (440)
- Highly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells. (2003) (422)
- Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice. (1990) (335)
- Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia (2017) (332)
- Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug. (2014) (315)
- Genotoxicity of retroviral integration in hematopoietic cells. (2006) (312)
- Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner. (2005) (291)
- Distinct Genomic Integration of MLV and SIV Vectors in Primate Hematopoietic Stem and Progenitor Cells (2004) (266)
- Ex vivo expansion of genetically marked rhesus peripheral blood progenitor cells results in diminished long-term repopulating ability. (1998) (251)
- Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia (2018) (249)
- Polyclonal long-term repopulating stem cell clones in a primate model. (2002) (247)
- Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome. (2004) (241)
- Outcomes and risks of granulocyte colony-stimulating factor in patients with coronary artery disease. (2005) (231)
- Antithymocyte Globulin for Treatment of the Bone Marrow Failure Associated with Myelodysplastic Syndromes (2002) (226)
- CD34+ cell dose predicts survival, posttransplant morbidity, and rate of hematologic recovery after allogeneic marrow transplants for hematologic malignancies (1996) (212)
- Eltrombopag and improved hematopoiesis in refractory aplastic anemia. (2012) (208)
- Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial. (2003) (205)
- AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates. (2006) (196)
- Retroviral transfer of the glucocerebrosidase gene into CD34+ cells from patients with Gaucher disease: in vivo detection of transduced cells without myeloablation. (1998) (168)
- Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells (2011) (164)
- Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus-based lentiviral vector system. (2004) (163)
- Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells. (2005) (162)
- Improved retroviral gene transfer into murine and Rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor. (1996) (159)
- Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells. (2014) (149)
- Molecular characterisation of side population cells with cancer stem cell-like characteristics in small-cell lung cancer (2010) (149)
- American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells. (2003) (148)
- Retroviral-mediated gene transfer into CD34-enriched human peripheral blood stem cells. (1993) (147)
- Rabaptin-5 is a novel fusion partner to platelet-derived growth factor beta receptor in chronic myelomonocytic leukemia. (2001) (146)
- Engraftment of MDR1 and NeoR gene-transduced hematopoietic cells after breast cancer chemotherapy. (1999) (139)
- Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque. (2006) (138)
- Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients. (1999) (136)
- Activity of STI571 in chronic myelomonocytic leukemia with a platelet-derived growth factor beta receptor fusion oncogene. (2002) (135)
- High-dose cyclophosphamide in severe aplastic anaemia: a randomised trial (2000) (135)
- Patients with myeloid malignancies bearing PDGFRB fusion genes achieve durable long-term remissions with imatinib. (2014) (121)
- Tumor-specific recognition of human myeloma cells by idiotype-induced CD8(+) T cells. (2000) (117)
- Cytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 gene. (2007) (109)
- Prolonged high-level detection of retrovirally marked hematopoietic cells in nonhuman primates after transduction of CD34+ progenitors using clinically feasible methods. (2000) (108)
- Many multipotential gene-marked progenitor or stem cell clones contribute to hematopoiesis in nonhuman primates. (2000) (108)
- Donor demographic and laboratory predictors of allogeneic peripheral blood stem cell mobilization in an ethnically diverse population. (2008) (107)
- Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques. (2007) (101)
- Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates. (2001) (101)
- Relapse following discontinuation of imatinib mesylate therapy for FIP1L1/PDGFRA-positive chronic eosinophilic leukemia: implications for optimal dosing. (2007) (101)
- High-dose cyclophosphamide with autologous lymphocyte-depleted peripheral blood stem cell (PBSC) support for treatment of refractory chronic autoimmune thrombocytopenia. (2003) (96)
- Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity (2011) (94)
- Update on the use of nonhuman primate models for preclinical testing of gene therapy approaches targeting hematopoietic cells. (2001) (93)
- Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study. (2014) (93)
- Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia. (2004) (93)
- Treatment of Severe Combined Immunodeficiency Disease (SCID) due to Adenosine Deaminase Deficiency with CD34+ Selected Autologous Peripheral Blood Cells Transduced with a Human ADA Gene (Amendment). National Institutes of Health (1993) (90)
- Improved engraftment of human hematopoietic cells in severe combined immunodeficient (SCID) mice carrying human cytokine transgenes (1995) (87)
- Pharmacological Modulation of Humoral Immunity in a Nonhuman Primate Model of AAV Gene Transfer for Hemophilia B (2012) (82)
- Retroviral mediated transfer of the human multidrug resistance gene (MDR-1) into hematopoietic stem cells during autologous transplantation after intensive chemotherapy for metastatic breast cancer. (1994) (82)
- Hematopoietic stem-cell behavior in nonhuman primates. (2007) (81)
- An Introduction to the Analysis of Single-Cell RNA-Sequencing Data (2018) (80)
- Gene transfer into hematopoietic progenitor and stem cells: Progress and problems (1994) (79)
- Path to the clinic: assessment of iPSC-based cell therapies in vivo in a nonhuman primate model. (2014) (79)
- Retrovirus-mediated transfer and expression of the interleukin-3 gene in mouse hematopoietic cells result in a myeloproliferative disorder (1989) (79)
- Growth factors and stromal support generate very efficient retroviral transduction of peripheral blood CD34+ cells from Gaucher patients. (1995) (76)
- Introduction of a xenogeneic gene via hematopoietic stem cells leads to specific tolerance in a rhesus monkey model. (2000) (74)
- Multilineage involvement of the fusion gene in patients with FIP1L1/PDGFRA‐positive hypereosinophilic syndrome (2006) (74)
- Gene transfer to hematopoietic stem cells: implications for gene therapy of human disease. (1996) (73)
- Mobilization as a preparative regimen for hematopoietic stem cell transplantation. (2004) (73)
- Hematopoietic stem cell engineering at a crossroads. (2012) (73)
- Retroviral marking and transplantation of rhesus hematopoietic cells by nonmyeloablative conditioning. (1999) (73)
- Human gene marker/therapy clinical protocols. (1996) (73)
- Antibody-mediated cell labeling of peripheral T cells with micron-sized iron oxide particles (MPIOs) allows single cell detection by MRI. (2007) (72)
- CD34+ cell dose predicts survival, posttransplant morbidity, and rate of hematologic recovery after allogeneic marrow transplants for hematologic malignancies. (1996) (72)
- Retroviral gene transduction of adult peripheral blood or marrow-derived CD34+ cells for six hours without growth factors or on autologous stroma does not improve marking efficiency assessed in vivo. (1997) (71)
- Intercellular transfer to signaling endosomes regulates an ex vivo bone marrow niche (2009) (68)
- Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ. (2019) (67)
- An AAVS1-targeted minigene platform for correction of iPSCs from all five types of chronic granulomatous disease. (2015) (66)
- Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs. (2013) (66)
- Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells. (2017) (65)
- The MDS1-EVI1 gene complex as a retrovirus integration site: impact on behavior of hematopoietic cells and implications for gene therapy. (2008) (64)
- In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene. (2009) (64)
- Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag. (2019) (62)
- Prediction and prevention of transplant-related mortality from pulmonary causes after total body irradiation and allogeneic stem cell transplantation. (2005) (61)
- IFN‐γ regulates survival and function of tumor‐induced CD11b+Gr‐1high myeloid derived suppressor cells by modulating the anti‐apoptotic molecule Bcl2a1 (2014) (60)
- The effect of multidrug-resistance 1 gene versus neo transduction on ex vivo and in vivo expansion of rhesus macaque hematopoietic repopulating cells. (2001) (59)
- Long-term in vivo expression of the human glucocerebrosidase gene in nonhuman primates after CD34+ hematopoietic cell transduction with cell-free retroviral vector preparations. (1995) (57)
- Human and rhesus macaque hematopoietic stem cells cannot be purified based only on SLAM family markers. (2011) (56)
- Development of an inducible caspase-9 safety switch for pluripotent stem cell–based therapies (2014) (56)
- Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells. (2009) (56)
- Genetically modified CD34+ hematopoietic stem cells contribute to turnover of brain perivascular macrophages in long-term repopulated primates. (2009) (53)
- iPSCs and fibroblast subclones from the same fibroblast population contain comparable levels of sequence variations (2017) (53)
- Bone marrow homing and engraftment of human hematopoietic stem and progenitor cells is mediated by a polarized membrane domain. (2012) (52)
- Granulocyte colony-stimulating factor recruitment of CD34+ progenitors to peripheral blood : Impaired mobilization in chronic granulomatous disease and adenosine deaminase-deficient severe combined immunodeficiency disease patients (1996) (51)
- Transient in vivo selection of transduced peripheral blood cells using antifolate drug selection in rhesus macaques that received transplants with hematopoietic stem cells expressing dihydrofolate reductase vectors. (2004) (51)
- Human gene marker/therapy clinical protocols. (1999) (51)
- Retroviral transduction efficiency of G-CSF+SCF-mobilized peripheral blood CD34+ cells is superior to G-CSF or G-CSF+Flt3-L-mobilized cells in nonhuman primates. (2003) (51)
- Challenges in vector and trial design using retroviral vectors for long-term gene correction in hematopoietic stem cell gene therapy. (2012) (50)
- A new spontaneous mouse mutation in the Kcne1 gene (2000) (50)
- Retroviral mediated transfer of the cDNA for human glucocerebrosidase into hematopoietic stem cells of patients with Gaucher disease. A phase I study. (1996) (49)
- Molecular and serological examination of the relationship of human herpesvirus 8 to multiple myeloma: orf 26 sequences in bone marrow stroma are not restricted to myeloma patients and other regions of the genome are not detected. (1998) (47)
- Long-term culture of chronic myelogenous leukemia marrow cells on stem cell factor-deficient stroma favors benign progenitors. (1995) (47)
- Quantitative stability of hematopoietic stem and progenitor cell clonal output in rhesus macaques receiving transplants. (2017) (47)
- Absence of donor-derived keratinocyte stem cells in skin tissues cultured from patients after mobilized peripheral blood hematopoietic stem cell transplantation. (2002) (46)
- Assessing the risks of genotoxicity in the therapeutic development of induced pluripotent stem cells. (2013) (46)
- Gene marking and gene therapy directed at primary hematopoietic cells (1996) (46)
- Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells (2011) (45)
- Gene Editing of Human Hematopoietic Stem and Progenitor Cells: Promise and Potential Hurdles. (2016) (45)
- Correction of the disease phenotype in canine leukocyte adhesion deficiency using ex vivo hematopoietic stem cell gene therapy. (2006) (44)
- Retroviral mediated gene transfer of the Fanconi anemia complementation group C gene to hematopoietic progenitors of group C patients. (1997) (43)
- Separating the wheat from the chaff: selection of benign hematopoietic cells in chronic myeloid leukemia. (1992) (43)
- No Evidence for Clonal Selection Due to Lentiviral Integration Sites in Human Induced Pluripotent Stem Cells (2010) (42)
- Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy. (2011) (42)
- In vivo marking of rhesus monkey lymphocytes by adeno-associated viral vectors: direct comparison with retroviral vectors. (1999) (41)
- Dexpramipexole as an oral steroid-sparing agent in hypereosinophilic syndromes. (2018) (41)
- Positive selection of CD34+ hematopoietic cells using an immunoaffinity column results in T cell-depletion equivalent to elutriation. (1995) (40)
- The impact of low-dose busulfan on clonal dynamics in nonhuman primates. (2004) (40)
- Functional Niche Competition Between Normal Hematopoietic Stem and Progenitor Cells and Myeloid Leukemia Cells (2015) (39)
- Dynamic clonal analysis of murine hematopoietic stem and progenitor cells marked by 5 fluorescent proteins using confocal and multiphoton microscopy. (2012) (38)
- In vivo persistence of retrovirally transduced murine long-term repopulating cells is not limited by expression of foreign gene products in the fully or minimally myeloablated setting. (2001) (38)
- Geographic clonal tracking in macaques provides insights into HSPC migration and differentiation (2018) (37)
- Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders. (2015) (36)
- Large Animal Models for Stem and Progenitor Cell Analysis (2005) (36)
- The impact of aging on primate hematopoiesis as interrogated by clonal tracking. (2018) (35)
- Measurement of the absolute immature platelet number reflects marrow production and is not impacted by platelet transfusion (2012) (35)
- Granulocyte colony-stimulating factor recruitment of CD34+ progenitors to peripheral blood: impaired mobilization in chronic granulomatous disease and adenosine deaminase--deficient severe combined immunodeficiency disease patients. (1996) (35)
- Reduced genotoxicity of avian sarcoma leukosis virus vectors in rhesus long-term repopulating cells compared to standard murine retrovirus vectors. (2008) (35)
- Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with CD34+ selected autologous peripheral blood cells transduced with a human ADA gene. Amendment to clinical research project, Project 90-C-195, January 10, 1992. (1993) (35)
- Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction. (1994) (34)
- Clonal expansion and compartmentalized maintenance of rhesus macaque NK cell subsets (2018) (34)
- Acquired somatic mutations in PNH reveal long-term maintenance of adaptive NK cells independent of HSPCs. (2017) (34)
- In Vivo Tracking of Adoptively Transferred Natural Killer Cells in Rhesus Macaques Using 89Zirconium-Oxine Cell Labeling and PET Imaging (2020) (32)
- Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia. (2011) (32)
- Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes (2013) (31)
- Introduction to clinical applications of stem cells at the National Institutes of Health: a meeting held on 24 May 2004 at the Clinical Center of the National Institutes of Health, Bethesda, Maryland, USA (2004) (31)
- Amendment to clinical research projects. Genetic marking with retroviral vectors to study the feasibility of stem cell gene transfer and the biology of hematopoietic reconstitution after autologous transplantation in multiple myeloma, chronic myelogenous leukemia, or metastatic breast cancer. (1993) (30)
- Differences in the Phenotype, Cytokine Gene Expression Profiles, and In Vivo Alloreactivity of T Cells Mobilized with Plerixafor Compared with G-CSF (2013) (30)
- Genetic marking as an approach to studying in vivo hematopoiesis: progress in the non-human primate model (2002) (30)
- Adeno-associated virus serotype 2-mediated gene transfer to the parotid glands of nonhuman primates. (2007) (29)
- Hematopoietic stem cell gene therapy: dead or alive? (2005) (29)
- Transduction of hematopoietic stem cells in humans and in nonhuman primates (1997) (28)
- Transcriptome analysis reveals similarities between human blood CD3− CD56bright cells and mouse CD127+ innate lymphoid cells (2017) (28)
- T cell receptor VB repertoire diversity in patients with immune thrombocytopenia following splenectomy (2003) (27)
- Sorting of transgenic secretory proteins in rhesus macaque parotid glands after adenovirus-mediated gene transfer. (2008) (27)
- High efficiency restriction enzyme-free linear amplification-mediated polymerase chain reaction approach for tracking lentiviral integration sites does not abrogate retrieval bias. (2013) (27)
- 5‐AZACYTIDINE TREATMENT IN A βo‐THALASSAEMIC PATIENT UNABLE TO BE TRANSFUSED DUE TO MULTIPLE ALLOANTIBODIES (1989) (27)
- Ex vivo expansion of retrovirally transduced primate CD34+ cells results in overrepresentation of clones with MDS1/EVI1 insertion sites in the myeloid lineage after transplantation. (2010) (27)
- Regulated Apoptosis of Genetically Modified Hematopoietic Stem and Progenitor Cells Via an Inducible Caspase‐9 Suicide Gene in Rhesus Macaques (2015) (26)
- Eltrombopag mobilizes iron in patients with aplastic anemia. (2018) (25)
- Low-dose total body irradiation causes clonal fluctuation of primate hematopoietic stem and progenitor cells. (2005) (25)
- Primary T lymphocytes as targets for gene therapy. (2000) (25)
- The Impact of ex Vivo Cytokine Stimulation on Engraftment of Primitive Hematopoietic Cells in a Non‐Human Primate Model (2001) (25)
- Eltrombopag monotherapy can improve hematopoiesis in patients with low to intermediate risk-1 myelodysplastic syndrome. (2020) (25)
- Retroviral transduction of CD34-enriched hematopoietic progenitor cells under serum-free conditions. (1996) (23)
- Combination therapy with rFVIIa and platelets for hemorrhage in patients with severe thrombocytopenia and alloimmunization (2006) (23)
- Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque. (2019) (23)
- Prolonged multilineage clonal hematopoiesis in a rhesus recipient of CD34 positive cells marked with a RD114 pseudotyped oncoretroviral vector. (2003) (23)
- Eltrombopag for patients with moderate aplastic anemia or uni-lineage cytopenias. (2020) (23)
- Thymidine kinase suicide gene-mediated ganciclovir ablation of autologous gene-modified rhesus hematopoiesis. (2012) (23)
- Gene Transfer into Hematopoietic Cells: Implications for Cancer Therapy (1994) (23)
- GATA2 deficiency and human hematopoietic development modeled using induced pluripotent stem cells. (2018) (22)
- BCL2A1a Over-Expression in Murine Hematopoietic Stem and Progenitor Cells Decreases Apoptosis and Results in Hematopoietic Transformation (2012) (22)
- Analysis of origin and optimization of expansion and transduction of circulating peripheral blood endothelial progenitor cells in the rhesus macaque model. (2002) (22)
- Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia Accelerates Count Recovery and Increases Response Rates (2015) (21)
- Gene therapy activates EVI1, destabilizes chromosomes (2010) (20)
- Retroviral-mediated transfer of interleukin-6 into hematopoietic cells of mice results in a syndrome resembling Castleman's disease. (1990) (20)
- Efficient Characterization of Retro‐, Lenti‐, and Foamyvector‐Transduced Cell Populations by High‐Accuracy Insertion Site Sequencing (2003) (20)
- Retroviral transduction and engraftment ability of primate hematopoietic progenitor and stem cells transduced under serum-free versus serum-containing conditions. (2002) (19)
- Genetic manipulation of hematopoietic stem cells. (2004) (19)
- CNS interleukin-3 (IL-3) expression and neurological syndrome in antisense-IL-3 transgenic mice. (1999) (19)
- Improved Amphotropic Retrovirus‐Mediated Gene Transfer into Hematopoietic Stem Cells (1998) (19)
- Rhesus iPSC Safe Harbor Gene-Editing Platform for Stable Expression of Transgenes in Differentiated Cells of All Germ Layers. (2017) (19)
- Anti-interleukin-2 receptor antibody (daclizumab) treatment of corticosteroid-refractory autoimmune thrombocytopenic purpura. (2006) (19)
- Human hematopoietic stem cells from mobilized peripheral blood can be purified based on CD49f integrin expression. (2015) (19)
- Effect of chronic cytokine therapy on clonal dynamics in nonhuman primates. (2004) (18)
- Large granular lymphocytic proliferation‐associated cyclic thrombocytopenia (2005) (18)
- Busulfan Combined with Immunosuppression Allows Efficient Engraftment of Gene-Modified Cells in a Rhesus Macaque Model. (2019) (18)
- Efficient differentiation of cardiomyocytes and generation of calcium-sensor reporter lines from nonhuman primate iPSCs (2018) (17)
- Direct comparison of RD114-pseudotyped versus amphotropic-pseudotyped retroviral vectors for transduction of rhesus macaque long-term repopulating cells. (2003) (17)
- Contributions of gene marking to cell and gene therapies. (2011) (17)
- Graft-versus-host disease: role of inflammation in the development of chromosomal abnormalities of keratinocytes. (2010) (17)
- Transient silencing of PTEN in human CD34(+) cells enhances their proliferative potential and ability to engraft immunodeficient mice. (2012) (16)
- No Evidence of Clonal Dominance in Primates up to 4 Years Following Transplantation of Multidrug Resistance 1 Retrovirally Transduced Long‐Term Repopulating Cells (2007) (16)
- Hematopoietic stem cell gene therapy:assessing the relevance of preclinical models. (2013) (16)
- Integration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34+ Cells Correlates With In Vivo Vector Copy Number (2013) (15)
- Imatinib-Responsive Hypereosinophilia in a Patient with B Cell ALL (2004) (15)
- The presence of the carboxy-terminal fragment of fibronectin allows maintenance of non-human primate long-term hematopoietic repopulating cells during extended ex vivo culture and transduction. (2004) (15)
- REVIEW The use of nonhuman primate models to improve gene transfer into haematopoietic stem cells (2001) (15)
- No discrepancy between in vivo gene marking efficiency assessed in peripheral blood populations compared with bone marrow progenitors or CD34+ cells. (1999) (15)
- Transduction of rhesus macaque hematopoietic stem and progenitor cells with avian sarcoma and leukosis virus vectors. (2007) (15)
- Stem Cell Gene Transfer: Insights into Integration and Hematopoiesis from Primate Genetic Marking Studies (2005) (14)
- Update on hematopoietic stem cell gene transfer using non-human primate models. (2002) (14)
- The yin and yang of stem cell gene therapy: insights into hematopoiesis, leukemogenesis, and gene therapy safety. (2007) (14)
- Plasticity and hematopoiesis: Circe's transforming potion? (2002) (14)
- CRISPR/Cas9 PIG -A gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs. (2019) (13)
- Workshop on long-term follow-up of participants in human gene transfer research. (2004) (13)
- Glucocorticoid-induced eosinopenia results from CXCR4-dependent bone marrow migration. (2020) (12)
- Assessment of rapid remobilization intervals with G–CSF and SCF in murine and rhesus macaque models (2001) (12)
- Pilot study of high dose ICE (ifosfamide, carboplatin, etoposide) chemotherapy and autologous bone marrow transplant (ABMT) with neoR-transduced bone marrow and peripheral blood stem cells in patients with metastatic breast cancer. (1993) (12)
- Modeling Human Bone Marrow Failure Syndromes Using Pluripotent Stem Cells and Genome Engineering. (2015) (12)
- Impact of CMV Infection on Natural Killer Cell Clonal Repertoire in CMV-Naïve Rhesus Macaques (2019) (12)
- Telomere dynamics and hematopoietic differentiation of human DKC1-mutant induced pluripotent stem cells. (2019) (12)
- In vivo gene marking of rhesus macaque long‐term repopulating hematopoietic cells using a VSV‐G pseudotyped versus amphotropic oncoretroviral vector (2004) (11)
- In Vitro Culture During Retroviral Transduction Improves Thymic Repopulation and Output After Total Body Irradiation and Autologous Peripheral Blood Progenitor Cell Transplantation in Rhesus Macaques (2006) (11)
- The Role of Nonhuman Primate Animal Models in the Clinical Development of Pluripotent Stem Cell Therapies. (2016) (11)
- A new direction for gene therapy: intrathymic T cell-specific lentiviral gene transfer. (2005) (11)
- Eltrombopag for Refractory Severe Aplastic Anemia: Dosing Regimens, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling (2017) (10)
- Persistent elevation of plasma thrombopoietin levels after treatment in severe aplastic anemia. (2017) (10)
- Blood's 70th anniversary: CARs on the Blood highway. (2016) (9)
- In vivo clonal tracking of hematopoietic stem and progenitor cells marked by five fluorescent proteins using confocal and multiphoton microscopy. (2014) (9)
- Thrombopoietic status of patients on haemodialysis (2016) (9)
- Human gene marker/therapy clinical protocols. (1997) (9)
- 'Ghostbusting' at blood. (2009) (9)
- Integration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34+ Cells Correlates With In Vivo Vector Copy Number. (2013) (8)
- Feline Leukemia Virus Integrase And Capsid Packaging Functions Do Not Change The Insertion Profile Of Standard Moloney Retroviral Vectors (2010) (8)
- Repetitive busulfan administration after hematopoietic stem cell gene therapy associated with a dominant HDAC7 clone in a nonhuman primate. (2010) (8)
- Gene therapy approaches for multiple myeloma. (2001) (8)
- Interrogation of clonal tracking data using barcodetrackR (2021) (8)
- Retroviral-mediated transfer of the murine interleukin-3 gene engineered for intracellular retention results in a myeloproliferative syndrome but is associated with circulating interleukin-3 levels. (1993) (8)
- BM-derived cell therapies for cardiovascular disease. (2007) (8)
- A Novel Method to Study the in Vivo Trafficking and Homing of Adoptively Transferred NK Cells in Rhesus Macaques and Humans (2014) (7)
- Barcoding of Macaque Hematopoietic Stem and Progenitor Cells: A Robust Platform to Assess Vector Genotoxicity (2018) (7)
- Statistical inference for partially observed branching processes with application to cell lineage tracking of in vivo hematopoiesis (2016) (7)
- 564. The Cytotoxic Effect of RNA-Guided Endonuclease Cas9 on Human Hematopoietic Stem and Progenitor Cells (HSPCs) (2016) (7)
- Clonal tracking of haematopoietic cells: insights and clinical implications (2020) (7)
- CRISPR/Cas9-Based Safe-Harbor Gene Editing in Rhesus iPSCs. (2017) (7)
- Interferon-γ Perturbs Key Signaling Pathways Induced By Thrombopoietin, but Not Eltrombopag, in Human Hematopoietic Stem/Progenitor Cells (2016) (7)
- HOXB4 and retroviral vectors: adding fuel to the fire. (2008) (6)
- GMA161 Treatment of Refractory ITP: Efficacy of Fcγ-RIII Blockade. (2006) (6)
- CRISPR/Cas9‐mediated introduction of the sodium/iodide symporter gene enables noninvasive in vivo tracking of induced pluripotent stem cell‐derived cardiomyocytes (2020) (6)
- Predictors of clonal evolution and myeloid neoplasia following immunosuppressive therapy in severe aplastic anemia (2022) (6)
- Macaque Clonal Hematopoiesis Model Demonstrates Expansion of TET2-Disrupted Clones and Utility for Testing Interventions. (2022) (6)
- Even “Moderate” Dose Cyclophosphamide for Severe Aplastic Anemia Is Associated with Significant Toxicities and Does Not Prevent Relapse and Clonal Evolution (2012) (6)
- The use of nonhuman primate models to improve gene transfer into haematopoietic stem cells. (2001) (6)
- Rhesus Macaque iPSC Generation and Maintenance. (2017) (5)
- Prediction and Validation of Hematopoietic Stem and Progenitor Cell Off-Target Editing in Transplanted Rhesus Macaques. (2021) (5)
- Eltrombopag Can Stimulate Trilineage Hematopoiesis with Transfusion Independence in Patients with Refractory Severe Aplastic Anemia: Results From a Phase II Trial (2011) (5)
- Hematopoietic Stem Cell Behavior in Non-human Primates (2007) (5)
- No impact of lentiviral transduction on hematopoietic stem/progenitor cell telomere length or gene expression in the rhesus macaque model. (2014) (5)
- CD9 up-regulation on CD34+ cells with ingenol 3,20-dibenzoate does not improve homing in NSG mice. (2011) (5)
- Keratinocyte Growth Factor Increases Thymic Output of Naïve T-Cells after Total Body Irradiation and Autologous Peripheral Blood Progenitor Cell Transplantation in Rhesus Macaques. (2005) (4)
- Lentiviruses get specific (2002) (4)
- Clonal hematopoiesis is not significantly associated with COVID-19 disease severity (2022) (4)
- Lack of benefit from cytokine mobilized stem cell therapy for acute myocardial infarction in nonhuman primates (2003) (4)
- Studies in a mosaic DBA patient and chimeric mice reveal erythroid cell-extrinsic contributions to erythropoiesis. (2022) (4)
- A plethora of gene therapies for hemoglobinopathies (2021) (4)
- Comparative Results of Gene Therapy for Adenosine Deaminase Deficiency with or without PEG-ADA Withdrawal and Myelosuppressive Chemotherapy. (2007) (4)
- Stem and progenitor cell therapies: insights from non-human primate models. (2004) (4)
- An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human Primates (2019) (4)
- Gene therapy for hematologic disease: Don't throw the baby out with the bathwater! (2004) (4)
- In vivo models for studying the role of autocrine or paracrine growth factors in hematologic malignancies. (1995) (4)
- Immunosuppression and growth factors for severe aplastic anemia: new data for old questions (2020) (4)
- Understanding and Overcoming Adverse Consequences of Genome Editing on Hematopoietic Stem and Progenitor Cells. (2021) (4)
- Intrabone transplantation of CD34+ cells with optimized delivery does not enhance engraftment in a rhesus macaque model. (2020) (4)
- A Pilot Study Of Rituximab In Patients With Moderate Aplastic Anemia, Diamond-Blackfan Anemia and Pure Red Cell Aplasia (2013) (4)
- 56 ELTROMBOPAG FOR LOW TO INTERMEDIATE-2 RISK MYELODYSPLASTIC SYNDROME (2015) (3)
- The Thrombopoietin Receptor Agonist Eltrombopag Has DNA Repair Activity in Human Hematopoietic Stem and Progenitor Cells (2015) (3)
- Resetting the immune system in immune thrombocytopenic purpura: immunoablative strategies. (2003) (3)
- Bone Marrow as a Source of Cells for Paroxysmal Nocturnal Hemoglobinuria Detection (2018) (3)
- Highlights from the third annual ASGT meeting. American Society of Gene Therapy. (2000) (3)
- Clonal tracking of erythropoiesis in rhesus macaques (2019) (3)
- Statistical inference in partially observed stochastic compartmental models with application to cell lineage tracking of in vivo hematopoiesis (2016) (3)
- Differential diagnosis of bone marrow failure syndromes guided by machine learning. (2022) (3)
- Successful Treatment of a Diamond-Blackfan Anemia (DBA) Patient with Eltrombopag (2016) (3)
- Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene. (1999) (3)
- Sox4 Downregulates Pu.1 Gene Expression by Binding to An Upper Regulatory Element of Pu.1, a Mechanism Contributing to Leukemogenesis. (2009) (3)
- 53 – Hematopoietic Stem Cell Mobilization and Homing (2004) (2)
- A Non-Human Primate CRISPR/Cas9 Model of Clonal Hematopoiesis of Indeterminate Potential Demonstrates Expansion of TET2-Disrupted Clones (2017) (2)
- Gene Therapy for Hematological Disorders (2002) (2)
- Eltrombopag in aplastic anaemia (2015) (2)
- 387. Myeloid Sarcoma Associated with Gene Marking of Hematopoietic Stem Cells in a Rhesus Macaque (2005) (2)
- Dexpramipexole As a Steroid-Sparing Agent in Hypereosinophilic Syndromes (HES): An Open-Label Proof-of-Concept Study (2016) (2)
- Eltrombopag Improves Hematopoiesis in Patients with Low to Intermediate-2 Risk Myelodysplastic Syndrome (MDS) (2018) (2)
- Clonal Hematopoiesis Analyses in Clinical, Epidemiologic, and Genetic Aging Studies to Unravel Underlying Mechanisms of Age-Related Dysfunction in Humans (2022) (2)
- Faculty of 1000 evaluation for Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression. (2018) (2)
- Comparative engraftment and clonality of macaque HSPCs expanded on human umbilical vein endothelial cells versus non-expanded cells (2021) (2)
- Sources and Methods for Obtaining Stem and Progenitor Cells (2005) (2)
- Lineage Analysis of the FIPL1-PDGFRα Fusion Gene in Myeloproliferative Hypereosinophilic Syndrome. (2004) (2)
- Detection of Single Particles and Single Cells by MRI (2003) (2)
- In Vitro Culture during Retroviral Transduction Improves Thymic Repopulation and Output after TBI and Autologous PBPC Transplantation in Rhesus Macaques. (2004) (2)
- Macaque CRISPR/Cas9 Age-Related Clonal Hematopoiesis Model Demonstrates Expansion of TET2-Mutated Clones and Applicability for Testing Mitigation Approaches (2020) (2)
- Distinctive Integration Profile of Avian Sarcoma Leukosis Virus Vectors in Rhesus Long-Term Repopulating Cells. (2007) (2)
- Reduced Genotoxicity of Avian Sarcoma Leukosis Virus Vectors in Rhesus Long-term Repopulating Cells Compared to Standard Murine Retrovirus Vectors. (2008) (2)
- Special report Collection of hematopoietic stem cells from patients with autoimmune diseases (2001) (2)
- 707. Retroviral insertion site analysis in rhesus macaques transplanted with CD34+ hematopoietic stem cells transduced with a simian immunodeficiency virus-based lentiviral vector (2004) (2)
- Blood and the American Society of Hematology in 2008: looking back and moving forward (2008) (2)
- Expanded NK cells used for adoptive cell therapy maintain diverse clonality and contain long-lived memory-like NK cell populations (2022) (2)
- Analysis of Clonal Contributions to T Lymphoid and Myeloid Lineages during Early Hematopoiesis Following Autologous Transplantation in the Rhesus Macaque. (2004) (1)
- Long‐term eltrombopag for bone marrow failure depletes iron (2022) (1)
- Recurrent Retroviral Vector Integration at the MDS1-EVI1 Locus in Rhesus Long-Term Repopulating Hematopoietic Stem Cells. (2004) (1)
- HEMATOPOIETIC STEM CELL GENE THERAPY: ASSESSING THE RELEVANCE OF PRE-CLINICAL MODELS (2013) (1)
- Evaluation of a rapamycin-regulated serotype 2 adeno-associated viral vector in macaque parotid glands. (2010) (1)
- An educational infusion: more synergy between Blood and the American Society of Hematology. (2012) (1)
- Strong Predictors of Chromosomal Aberrations and Myeloid Neoplasia Following Immunosuppression Therapy for Severe Aplastic Anemia: A Retrospective Cohort Study (2021) (1)
- Validation and Long-Term Follow Up of CD33 Off-Targets Predicted In Vitro and In Silico Using Error-Corrected Sequencing in Rhesus Macaques (2020) (1)
- Transient in vivo selection of transduced peripheral blood cells using antifolate drug selection in rhesus macaques transplanted with hematopoietic stem cells expressing dihydrofolate reductase vectors (2003) (1)
- barcodetrackR: an R package for the interrogation of clonal tracking data (2020) (1)
- Progress Towards Creation of a Rhesus Macaque Animal Model for PNH Disease Via Crispr/Cas9 Technology to Knock out the PIG-a Gene (2014) (1)
- IL-15 Administration to In-Vivo Expand Adoptively Transferred NK Cells In Rhesus Macaques (2010) (1)
- George Stamatoyannopoulos (1934–2018) (2018) (1)
- Aberrant Clonal Hematopoiesis of the Erythroid and Myeloid Lineages in a Lentivirally Barcoded Rhesus Macaque (2017) (1)
- Genomic-Based Machine Learning Towards Prediction of the Etiology of Bone Marrow Failure Syndromes (2021) (1)
- Tissue Trafficking Kinetics of Rhesus Macaque Natural Killer Cells Measured by Serial Intravascular Staining (2022) (1)
- Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure (2018) (1)
- A Diamond-Blackfan Anemia Patient's Response to Eltrombopag and Genomic Analysis in Different Lineages (2020) (1)
- Identification and Ex Vivo Expansion of a Circulating NK Cell Progenitor Population That Leads to Sustained Production of CD56+ NK Cells (2015) (1)
- Long-term culture of CML marrow on stem cell factor-deficient stroma favors-benign progenitors (1993) (1)
- NADPH oxidase correction by mRNA transfection of apheresis granulocytes in chronic granulomatous disease. (2020) (1)
- Applying a clinical lens to animal models of CAR-T cell therapies (2022) (1)
- Bone marrow skeletal stem / progenitor cell defects in patients with dyskeratosis congenita and telomere biology disorders (2014) (1)
- Estimating the Replication Rate of Hematopoietic Stem Cells in Non-Human Primates: A Test of Hayflick’s Hypothesis. (2005) (1)
- Persistent Elevation of Plasma Thrombopoietin Levels in Severe Aplastic Anemia, Even with Hematologic Recovery (2015) (1)
- Long-Term Polyclonal and Stable Gene Transfer into Rhesus Repopulating Hematopoietic Stem Cells Using a Simian Immunodeficiency Virus-Based Lentiviral Vector System. (2006) (1)
- Analysis of Viral Integration Sites in Human Induced Pluripotent Stem Cells. (2009) (1)
- 68: Gene Therapy for Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID): Comparative Results with or without PEG-ADA Withdrawal and Myelosuppressive Chemotherapy (2008) (1)
- Rhesus Macaque NK Cells Expanded Ex Vivo Undergo Similar Phenotypic and Functional Changes Observed With Expanded Human NK Cells Providing An Excellent Model To Optimize Adoptive NK Cell Transfer (2013) (1)
- “Ask and Ye Shall Receive” – Women, Stand Up and Be Counted! (2014) (1)
- AMD3100-Mobilized CD34+ Cells Are Phenotypically Different and Better Targets for Retroviral Transduction Than G-CSF-Mobilized CD34+ Cells in Rhesus Macaques. (2004) (1)
- Myeloid Neoplasm Gene Somatic Mutations in Patients with Severe Aplastic Anemia Treated with Eltrombopag and Standard Immunosuppression (2016) (1)
- Comparison of busulfan and total body irradiation conditioning on hematopoietic clonal dynamics following lentiviral gene transfer in rhesus macaques (2022) (1)
- The use of cytokines active on primitive hematopoietic cells and stromal or fibronectin support during transduction improves stable retroviral gene transfer into primate CD34+ hematopoietic cells to clinically relevant levels (1998) (1)
- Plerixafor Compared with G-CSF Alloreactivity of T Cells Mobilized with Expression Profiles, and In Vivo Differences in the Phenotype, Cytokine Gene (2013) (0)
- 732. Avian Sarcoma Leukosis Virus Vectors Can Transduce Rhesus Macaque HSCs and Result in a Potentially Safer Integration Profile (2006) (0)
- Transcriptome analysis reveals similarities between human blood CD3− CD56bright cells and mouse CD127+ innate lymphoid cells (2017) (0)
- New Aspects on the Safety of Multidrug-Resistance 1 Gene Transfers: No Indication for Clonal Dominance after Long-Term Follow-Up in a Primate Transplantation Model. (2004) (0)
- HSC Clonal Dynamics after T-Cell Depletion in a Nonhuman Primate Model of Lentiviral Gene Therapy (2016) (0)
- Long-Term Eltrombopag for Bone Marrow Failure Depletes Total Body Iron (2020) (0)
- Two Decades of ASGCT: Dreams Become Reality. (2017) (0)
- In vivo tracking of rhesus macaque eosinophils to assess migration in response to glucocorticoids: 583 (2019) (0)
- Leukemic and Hematopoietic Stem Cells Compete for the Same Functional Marrow Niche in a MLL-AF9 Murine Leukemia Model (2012) (0)
- Efficient differentiation of cardiomyocytes and generation of calcium-sensor reporter lines from nonhuman primate iPSCs (2018) (0)
- Tissue-Resident Clonal Expansions of Rhesus Macaque NK Cells (2021) (0)
- Repetitive Busulfan Administration Uncovers a Competitive Advantage for Hematopoietic Clones with a Retrovirus Insertion Near the HDAC7A Locus (2007) (0)
- Basic Studies Toward Hematopoietic Stem Cell Gene Therapy (2000) (0)
- Ex Vivo Expansion of Retrovirally-Transduced Primate CD34+ Cells Results in Preferential Engraftment and Persistence of Clones with MDS1/EVI1 Insertion Sites. (2006) (0)
- Culture of Mobilized Human CD34+ Cells in Hypoxic Conditions Improves Lentiviral Transduction Efficiency in SCID-Repopulating Cells (2008) (0)
- Factors Affecting Allogeneic Peripheral Blood Stem Cell Mobilization in a Large, Ethnically, Diverse Population. (2007) (0)
- 708. Retroviral Vector Integration into the Genome of Rhesus Macaque Long-Term Repopulating Cells (2004) (0)
- ASGCT co-founder and past president Arthur Nienhuis (1941-2021). (2021) (0)
- Hieh-Dose Immunosuppressive Chemotherapy with Autologous Stem Cell Support for Chronic Autoimmune Thrombocytopenia (2019) (0)
- Eltrombopag Can Stimulate Trilineage Hematopoiesis In Patients with Refractory Severe Aplastic Anemia (2010) (0)
- Response: More on ghostbusting (2009) (0)
- deficiency using ex-vivo hematopoietic stem cell gene therapy Correction of the disease phenotype in canine leukocyte adhesion (2013) (0)
- 3154 – RHESUS MACAQUES AS NATURAL MODELS FOR AGE-RELATED CLONAL HEMATOPOIESIS (2020) (0)
- 523. Human Umbilical Vein Endothelial Cell, HUVEC, Co-Culture Promotes Robust Expansion and Maintains Phenotypic Integrity of Rhesus Hematopoietic Stem and Progenitor Cells, HSPC, Prior to Autologous Tansplantation (2016) (0)
- The Unique Ontogeny Of Natural Killer Cells As Revealed By Genetic Barcoding In The Nonhuman Primate Model (2013) (0)
- Myeloma gets the measles (2001) (0)
- Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling (2018) (0)
- Investigation of the Impact of Clonal Hematopoiesis on Severity and Pathophysiology of COVID-19 in Rhesus Macaques (2023) (0)
- Quantitative Real Time PCR Analysis of MDR1 Transduced Rhesus Macaque Hematopoietic Stem Cells Shows No Indication for Proliferative Advantage after Long-Term Follow-Up. (2005) (0)
- CT-167 Using the Sodium Iodide Symporter to Visualize CAR-T Cell Trafficking. (2022) (0)
- A RUNX1-FPDMM rhesus macaque model reproduces the human phenotype and predicts challenges to curative gene therapies. (2022) (0)
- Abstract 193: CRISPR-mediated Introduction of the Sodium-iodide Symporter to Enable Non-invasive Monitoring of Macaque Induced-pluripotent Stem Cell-derived Cardiomyocytes (2017) (0)
- Transfer of genes in hematopoietic cells with retroviral vectors. (1988) (0)
- BCL2A1 Is a Survival and Immortalization Factor for Primitive Hematopoietic Cells. (2007) (0)
- Telomere Dynamics in Pluripotent Stem Cells Derived From Patients with Telomere Diseases (2011) (0)
- Patients, hematologists, and time. (2011) (0)
- Barcode clonal tracking of tissue-resident immune cells in rhesus macaque highlights distinct clonal distribution pattern of tissue NK cells (2022) (0)
- A Specialized Polarized Membrane Domain Found On Normal but Not Leukemic Hematopoietic Progenitor Cells Is Required for Homing to the Bone Marrow Microenvironment. (2009) (0)
- Clinical Protocol Amendment to Clinical Research Project Project 90-C-195 (1999) (0)
- MDS1-EVI1 and EVI1 Overexpression Results in Changes in the Behavior of Murine Hematopoietic Cells. (2006) (0)
- Mobilization for Gene Therapy (2012) (0)
- Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag (2020) (0)
- Aberrant Clonal Hematopoiesis Following Lentiviral Transduction of HSPC in a Rhesus Macaque (2019) (0)
- Granulocyte Transfusions As an Adjunctive Therapy in Severe Aplastic Anemia (2022) (0)
- Single Cell Transcriptome Analysis of GATA2 Deficiency in Hematopoiesis Modeled with Induced Pluripotent Stem Cells (2018) (0)
- Commitment and Promiscuity in the Twenty-First Century (2002) (0)
- Clonal Tracking of the Geographic Distribution of Hematopoiesis in Nonhuman Primates Provides New Insights into HSPC Migration and Differentiation (2015) (0)
- Keystone meeting on controversies in bone marrow transplantation : gene therapy workshop (1995) (0)
- Lentiviral Transduction of Nonhuman Primate Hematopoietic Stem and Progenitor Cells. (2023) (0)
- Human and Rhesus Macaque Hematopoietic Stem Cells Are Not Enriched in the CD150+CD48- SLAM Population. (2009) (0)
- Intrabone Delivery of CD34+ Cells Using an Optimized Delivery System Does Not Enhance Engraftment in a Rhesus Macaque Model of Hematopoietic Stem Cell Transplantation (2018) (0)
- aplastic anemia that can be sustained on discontinuation of drug Eltrombopag restores trilineage hematopoiesis in refractory severe (2014) (0)
- 62 Selectively depleting host-reactive T cells from peripheral blood stem cell allografts — preliminary results of a feasibility study (2003) (0)
- Ongoing Production of Tissue-Resident Macrophages from Hematopoietic Stem Cells in Healthy Adult Macaques (2022) (0)
- 241. Barcoding as a Tool To Predict Integrating Vector Genotoxicity in HSPCs (2015) (0)
- Gene and Cell Therapies in Expansion Mode: ASGCT 2016. (2016) (0)
- Characterization and isolation of rhesus macaque eosinophils (2018) (0)
- A Rhesus Macaque Model to Optimize Adoptive NK Cell Therapy (2008) (0)
- achieve durable long-term remissions with imatinib fusion genes PDGFRB Patients with myeloid malignancies bearing (2014) (0)
- Human gene marker/therapy clinical protocols. (1996) (0)
- Genotoxic Lemons Become Epigenomic Lemonade. (2018) (0)
- Clonal Dynamics of HDR-Edited HSPCs Targeting the CD33 Locus in Rhesus Macaques (2022) (0)
- Old before its time: age-related thymic dysfunction may preclude efficacy of gene therapy in older SCID-X1 patients (2005) (0)
- Insights into Clonal Relationships of Putative Adaptive Natural Killer Cells (NK) in Humans, Via Mapping of Somatic Piga Mutations in Patients with Paroxysmal Nocturna Hemoglobinuria (PNH) (2015) (0)
- PU.1 Cooperates with SOX4 in Myeloid Cells. (2007) (0)
- siRNA-Induced Transient Silencing of PTEN Expression Enhances Human Hematopoietic Cell Engraftment in NOD/SCID/γ c null Mice and Increases Gene Transduction Efficiency. (2008) (0)
- Repetitive Busulfan Administration Induces Emergence of Dominant and Expanding Hematopoietic Clones with Retroviral Vector Insertion in Rhesus Macaques (2008) (0)
- Single Cell RNA-Seq Characterization of an Adaptive Population of NK Cells after Primary CMV Infection in Rhesus Macaques (2021) (0)
- Proliferation of CD8 + T-Cells Specific for CMV and EBV in Response to TCR Mediated Recognition of Cognate Antigen Is Inhibited by Imatinib in a Dose-Dependent Manner. (2004) (0)
- Long-Term Hematopoietic Clonal Stability Tracked Using Molecular Barcoding in Non-Human Primates (2014) (0)
- Culture Of Mobilized Rhesus Macaque CD34+ Cells In Hypoxic Conditions Does Not Improve Lentiviral Transduction Efficiency In Long-Term Repopulating Hematopoietic Stem Cells (2013) (0)
- Abstract 467: Bcl2A1 - an IFN-gamma dependent master switch for the function of CD11b+Gr-1high myeloid derived suppressor cells. (2013) (0)
- A Platform Minigene AAVS1 Targeted Safe Harbor Approach For Genetic Correction Of iPSC Derived From Patients With Each Of The 5 Genetic Forms Of Chronic Granulomatous Disease (2013) (0)
- Evaluation of the Relationship between Clonal Hematopoiesis and Severe COVID-19 Disease in Rhesus Macaques (2021) (0)
- Gene Transfer to Hematopoietic Cells: Progress and Problems (1998) (0)
- Modeling Human Paroxysmal Nocturnal Hemoglobinuria Via CRISPR/Cas9 HSPC Gene Editing in Non-Human Primate (2018) (0)
- More frequent Blood transfusions. (2009) (0)
- Rhesus Macaques As a Preclinical Model Organism for RUNX1-FPD (2021) (0)
- Clonal Expansion and Long-Term Persistence of Rhesus Macaque NK Cells with an Adaptive Phenotype (2016) (0)
- Human gene marker/therapy clinical protocols. (2000) (0)
- Comparing the Impact of NHEJ-CRISPR/Cas9 and Base Gene Editing on Rhesus Macaque Hematopoietic Stem Cell Clonal Behavior and Integrity (2022) (0)
- Introducing "e-Blood". (2009) (0)
- Mobilization as a Preparative Regimen for Hematopoietic Stem Cell (HSC) Transplantation in Rhesus Macaques. (2005) (0)
- Long-Term, Clonal Tracking Comparing Autologous Transplantation of G-CSF/SCF-Primed Bone Marrow CD34+ Cells with G-CSF/SCF-Mobilized Peripheral Blood CD34+ Cells in Rhesus Macaques (2018) (0)
- Avian Sarcoma Leukosis Virus (ASLV) Derived Retroviral Vectors Efficiently Transduce CD34+ Cells and Have a Distinct Integration Profile in the Rhesus Macaque Transplantation Model. (2005) (0)
- 527. Improvement of Pre-Clinical Non-Human Primate Model for Pluripotent Stem Cell Based Therapies by Introducing Marker Genes in Safe Harbor Locus (2016) (0)
- Cynthia E . Dunbar and Stefan Fruehauf Farastuk Bozorgmehr , Stefanie Laufs , Stephanie E . Sellers , Ingo Roeder , Werner J . Repopulating Cells Transplantation of Multidrug Resistance 1 Retrovirally Transduced Long-Term (2007) (0)
- 705. AMD3100-Mobilized CD34+ Cells are phenotypically different and better targets for retroviral transduction than G-CSF-mobilized CD34+ Cells in rhesus macaques (2004) (0)
- Collaborative RISC-Score Database: Creation of an International Database for Retroviral Integration Analysis. (2004) (0)
- The Impact of Aging of Hematopoietic Stem and Progenitor Cells (HSPCs) in Non-Human Primates As Interrogated By Genetic Barcode Clonal Tracking (2015) (0)
- Suicide Gene (HSVtk) Ablation of Hematopoietic Stem Cells and Their Progeny In the Rhesus Macaque Model: An Approach to Deletion of Dangerous Clones. (2010) (0)
- from academia or the pharmaceutical and biomedical research industries, be fully acknowledged. (2017) (0)
- After Breast Cancer Chemotherapy Engraftment of MDR1 and NeoR Gene-Transduced Hematopoietic Cells (2013) (0)
- efficacy of gene therapy in older SCID-X1 patients Old before its time: age-related thymic dysfunction may preclude (2013) (0)
- 1009 – HSPC EDITING IN THE RHESUS MACAQUE TO MODEL HUMAN BIOLOGY AND TO DEVELOP NEW THERAPIES (2020) (0)
- Arginine metabolism regulates human erythroid differentiation through hypusination of eIF5A. (2023) (0)
- Development of an Inducible Caspase-9 Safety Switch for Pluripotent Stem Cell Based Therapies (2012) (0)
- Specific Impaired CD56+ NK Cell Development in GATA2 Deficiency As Revealed By Ex Vivo NK Expansion (2014) (0)
- 737. Induction of Molecular Chimerism in Rhesus Macaques Reconstituted with Autologous CD34+ Cells Transduced with the Gene Encoding the |[alpha]|(1-3)galactosyltranferase (|[alpha]|GT) (2005) (0)
- Tracking of long-term multi-lineage hematopoiesis in a rhesus macaque (2000) (0)
- 674. Administration of rAAV2 and rAAV5 to the Parotid Gland of Non-Human Primates (2006) (0)
- Genotoxicity in the rhesus macaque model (2008) (0)
- PU.1 Is a Downstream Target of SOX4 in Myeloid Cells. (2006) (0)
- Macaque Age-Related Clonal Hematopoiesis Model Demonstrates Expansion of TET2-Disrupted Clones and Utility for Testing Therapeutic Approaches (2020) (0)
- Keeping up with Blood: introducing our CME program. (2010) (0)
- Methylguanine Methyltransferase-Based In Vivo Selection Results in Only Transient Improvement in Long-Term Marking after Autologous Transplantation of Transduced Hematopoietic Stem Cells in Rhesus Macaques. (2006) (0)
- Human gene marker/therapy clinical protocols. (1999) (0)
- Stochastic Modeling of Hematopoietic Stem and Progenitor Cell Barcoding Data from Rhesus Macaques Challenges the Classic Model of Hematopoiesis (2016) (0)
- STEROID-SPARING IMMUNOSUPPRESSION FOR LONG TERM ALLOGENEIC STEM-CELL DERIVED CARDIOMYOCYTE TRANSPLANTATION IN MACAQUES (2023) (0)
- hematopoietic progenitor cells in a rhesus macaque Acute myeloid leukemia is associated with retroviral gene transfer to (2014) (0)
- Fluorescence in situ hybridization confirms the presence of Merkel cell polyomavirus in chronic lymphocytic leukemia cells (2011) (0)
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