David Allan Butterfield

David Allan Butterfield's AcademicInfluence.com Rankings

Biology

#2990

World Rank

#4643

Historical Rank

Neuroscience

#261

World Rank

#275

Historical Rank

biology Degrees

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Biology

David Allan Butterfield's Degrees

PhD Neuroscience University of California, San Francisco
Doctorate Medicine Stanford University

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David Allan Butterfield's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (2007) (1143)
Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide. (2001) (1109)
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. (1994) (1105)
Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress. (2002) (905)
An off-axis hydrothermal vent field near the Mid-Atlantic Ridge at 30° N (2001) (877)
Brain Regional Correspondence Between Alzheimer's Disease Histopathology and Biomarkers of Protein Oxidation (1995) (790)
Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease (2019) (749)
Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity. (2000) (710)
Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review. (2002) (688)
Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer’s disease brain contribute to neuronal death (2002) (680)
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase‐related protein 2, α‐enolase and heat shock cognate 71 (2002) (600)
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. (2002) (559)
Evidence of increased oxidative damage in subjects with mild cognitive impairment (2005) (536)
Proteomic identification of nitrated proteins in Alzheimer's disease brain (2003) (531)
Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death (1995) (519)
Protein oxidation in the brain in Alzheimer's disease (2001) (498)
Roles of amyloid β-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment (2007) (497)
The glial glutamate transporter, GLT‐1, is oxidatively modified by 4‐hydroxy‐2‐nonenal in the Alzheimer's disease brain: the role of Aβ1–42 (2001) (468)
Ferulic acid antioxidant protection against hydroxyl and peroxyl radical oxidation in synaptosomal and neuronal cell culture systems in vitro: structure-activity studies. (2002) (455)
The antioxidants α‐lipoic acid and N‐acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice (2003) (452)
Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins (2001) (428)
Amyloid β-peptide (1-42)-induced oxidative stress in Alzheimer disease: importance in disease pathogenesis and progression. (2013) (426)
Chapter 7 Protein Oxidation Processes in Aging Brain (1997) (418)
β-Amyloid Peptide Free Radical Fragments Initiate Synaptosomal Lipoperoxidation in a Sequence-Specific Fashion: Implications to Alzheimer′s Disease (1994) (403)
Lipid peroxidation triggers neurodegeneration: a redox proteomics view into the Alzheimer disease brain. (2013) (392)
Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia (2005) (386)
Nutritional approaches to combat oxidative stress in Alzheimer's disease. (2002) (378)
Oxidative stress in Alzheimer's disease brain: new insights from redox proteomics. (2006) (364)
Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: Insights into the development of Alzheimer's disease (2006) (363)
Collateral damage in cancer chemotherapy: oxidative stress in nontargeted tissues. (2007) (359)
Human endogenous retrovirus glycoprotein–mediated induction of redox reactants causes oligodendrocyte death and demyelination (2004) (358)
Obesity and hypertriglyceridemia produce cognitive impairment. (2008) (356)
Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach (2006) (356)
Oxidative stress precedes fibrillar deposition of Alzheimer’s disease amyloid β-peptide (1–42) in a transgenic Caenorhabditis elegans model (2003) (354)
30,000 Years of Hydrothermal Activity at the Lost City Vent Field (2003) (351)
Direct evidence of oxidative injury produced by the Alzheimer's β-Amyloid peptide (1–40) in cultured hippocampal neurons (1995) (343)
Geochemistry of hydrothermal fluids from Axial Seamount hydrothermal emissions study vent field, Juan de Fuca Ridge: Subseafloor boiling and subsequent fluid‐rock interaction (1990) (341)
beta-Amyloid-associated free radical oxidative stress and neurotoxicity: implications for Alzheimer's disease. (1997) (334)
In vitro and in vivo oxidative stress associated with Alzheimer's amyloid beta-peptide (1-42) (1999) (331)
Protective effect of quercetin in primary neurons against Abeta(1-42): relevance to Alzheimer's disease. (2009) (325)
Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: An approach to understand pathological and biochemical alterations in AD (2006) (321)
Protein carbonylation. (2010) (320)
Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1--42) and A beta(25--35). (2001) (310)
Elevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brain. (2014) (304)
Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders. (2007) (302)
Anomalous CH4 and NH4+ concentrations at an unsedimented mid-ocean-ridge hydrothermal system (1993) (298)
Oxidative Modification of Creatine Kinase BB in Alzheimer’s Disease Brain (2000) (295)
Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear explants (1996) (293)
The senescence-accelerated prone mouse (SAMP8): A model of age-related cognitive decline with relevance to alterations of the gene expression and protein abnormalities in Alzheimer's disease (2005) (289)
The Lipid Peroxidation Product, 4‐Hydroxy‐2‐trans‐Nonenal, Alters the Conformation of Cortical Synaptosomal Membrane Proteins (1997) (288)
Elevated concentrations of formate, acetate and dissolved organic carbon found at the Lost City hydrothermal field (2010) (286)
Role of oxidative stress in the progression of Alzheimer's disease. (2010) (285)
Free radicals and brain aging. (2004) (283)
Ferulic acid ethyl ester protects neurons against amyloid β‐ peptide(1–42)‐induced oxidative stress and neurotoxicity: relationship to antioxidant activity (2005) (278)
Measurement of oxidized/reduced glutathione ratio. (2010) (276)
Elevation of glutathione as a therapeutic strategy in Alzheimer disease. (2012) (273)
Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease. (2010) (266)
Gradients in the composition of hydrothermal fluids from the Endeavour segment vent field: Phase separation and brine loss (1994) (263)
Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis (2006) (254)
The critical role of methionine 35 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity. (2005) (249)
Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: insights into mechanism of neurodegeneration from redox proteomics. (2006) (248)
The Glutamatergic System and Alzheimer’s Disease (2003) (247)
Redox proteomic identification of 4-Hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: Insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease (2008) (244)
Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre‐clinical AD, amnestic mild cognitive impairment and late‐stage AD (2015) (244)
Amyloid β‐Peptide(1‐42) Contributes to the Oxidative Stress and Neurodegeneration Found in Alzheimer Disease Brain (2004) (241)
Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment (2006) (235)
Free radicals: key to brain aging and heme oxygenase as a cellular response to oxidative stress. (2004) (233)
Magmatic events can produce rapid changes in hydrothermal vent chemistry (2003) (231)
mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy (2015) (231)
Vitamin E Prevents Alzheimer's Amyloid beta-Peptide (1-42)-Induced Neuronal Protein Oxidation and Reactive Oxygen Species Production. (2000) (226)
Oxidative stress, protein modification and Alzheimer disease (2017) (224)
Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease. (2006) (224)
Proteomics analysis of the Alzheimer's disease hippocampal proteome. (2007) (219)
Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease: many pathways to neurodegeneration. (2010) (218)
Amyloid β Peptide (25–35) Inhibits Na+‐Dependent Glutamate Uptake in Rat Hippocampal Astrocyte Cultures (1996) (217)
Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: Implications for the role of nitration in the progression of Alzheimer's disease (2007) (217)
Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-α-phenylnitrone (1997) (217)
Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain (2004) (216)
Chemical, Physical, and Gel-forming Properties of Oxidized Myofibrils and Whey- and Soy-protein Isolates (2000) (214)
Submarine hydrothermal activity and gold-rich mineralization at Brothers Volcano, Kermadec Arc, New Zealand (2011) (210)
Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer’s Disease (2018) (206)
Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment. (2007) (205)
Bcl‐2 Protects Isolated Plasma and Mitochondrial Membranes Against Lipid Peroxidation Induced by Hydrogen Peroxide and Amyloid β‐Peptide (1998) (197)
Nitric oxide in cell survival: a janus molecule. (2009) (196)
Oxidative stress in HIV demented patients and protection ex vivo with novel antioxidants (2003) (194)
Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: Relevance to Alzheimer's disease (2008) (194)
Geochemistry of north Cleft segment vent fluids: Temporal changes in chlorinity and their possible relation to recent volcanism (1994) (192)
Oxidative stress and neurodegeneration (2017) (192)
Proteomic identification of HNE-bound proteins in early Alzheimer disease: Insights into the role of lipid peroxidation in the progression of AD (2009) (192)
Oxidatively modified proteins in Alzheimer’s disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis (2009) (188)
Oxidatively Induced Structural Alteration of Glutamine Synthetase Assessed by Analysis of Spin Label Incorporation Kinetics: Relevance to Alzheimer's Disease (1997) (188)
Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration (2003) (186)
4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: a toxic combination illuminated by redox proteomics studies. (2012) (184)
In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP. (2010) (184)
Adriamycin-induced, TNF-α-mediated central nervous system toxicity (2006) (183)
Abeta, oxidative stress in Alzheimer disease: evidence based on proteomics studies. (2014) (183)
Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease (2001) (182)
Survival of mussels in extremely acidic waters on a submarine volcano. (2009) (182)
Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: A nutritional approach (2003) (181)
Redox proteomics identification of 4‐hydroxynonenal‐modified brain proteins in Alzheimer's disease: Role of lipid peroxidation in Alzheimer's disease pathogenesis (2009) (177)
Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress. (2004) (174)
In-vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain (2000) (172)
Peroxynitrite‐Induced Alterations in Synaptosomal Membrane Proteins (1999) (172)
Methionine residue 35 is important in amyloid β-peptide-associated free radical oxidative stress (1999) (172)
Proteomic Analysis of Protein Expression and Oxidative Modification in R6/2 Transgenic Mice (2005) (172)
Intracellular Human Immunodeficiency Virus Tat Expression in Astrocytes Promotes Astrocyte Survival but Induces Potent Neurotoxicity at Distant Sites via Axonal Transport* (2003) (172)
Free radical mediated oxidative stress and toxic side effects in brain induced by the anti cancer drug adriamycin: Insight into chemobrain (2005) (171)
Adriamycin‐mediated nitration of manganese superoxide dismutase in the central nervous system: insight into the mechanism of chemobrain (2007) (170)
An increase in S‐glutathionylated proteins in the Alzheimer's disease inferior parietal lobule, a proteomics approach (2007) (169)
Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid β-peptide (1–42) into rat brain: Implications for Alzheimer’s disease (2005) (169)
Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes. (2004) (168)
The quantum event of oceanic crustal accretion: impacts of diking at mid-ocean ridges. (1998) (165)
Amyloid beta-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists. (2002) (164)
Structural and Functional Changes in Proteins Induced by Free Radical‐mediated Oxidative Stress and Protective Action of the Antioxidants N‐tert‐Butyl‐α‐phenylnitrone and Vitamin E a (1998) (162)
Redox proteomics in selected neurodegenerative disorders: from its infancy to future applications. (2012) (161)
Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: Involvement of the transcription factor Nrf2 (2005) (161)
Mitochondrial associated metabolic proteins are selectively oxidized in A30P α-synuclein transgenic mice—a model of familial Parkinson's disease (2005) (158)
Oxidatively Modified GST and MRP1 in Alzheimer’s Disease Brain: Implications for Accumulation of Reactive Lipid Peroxidation Products (2004) (157)
Increased expression of heat shock proteins in rat brain during aging: relationship with mitochondrial function and glutathione redox state (2004) (155)
Proteomic identification of oxidized mitochondrial proteins following experimental traumatic brain injury. (2007) (152)
Oxidative stress in Alzheimer disease and mild cognitive impairment: evidence from human data provided by redox proteomics (2015) (152)
Natural antioxidants in Alzheimer's disease (2007) (152)
Biological colonization of new hydrothermal vents following an eruption on Juan de Fuca Ridge (1997) (152)
Multifunctional roles of enolase in Alzheimer’s disease brain: beyond altered glucose metabolism (2009) (152)
Alumina nanoparticles induce expression of endothelial cell adhesion molecules. (2008) (151)
Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain (2004) (150)
Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia (2011) (150)
REVIEW: Pin1 in Alzheimer's disease (2006) (150)
Acetyl‐L‐carnitine‐induced up‐regulation of heat shock proteins protects cortical neurons against amyloid‐beta peptide 1–42‐mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease (2006) (150)
Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis. (2005) (148)
Elevated oxidative stress in models of normal brain aging and Alzheimer's disease. (1999) (147)
Submarine venting of phase-separated hydrothermal fluids at Axial Volcano, Juan de Fuca Ridge (1989) (144)
Amyloid beta-peptide [1-42]-associated free radical-induced oxidative stress and neurodegeneration in Alzheimer's disease brain: mechanisms and consequences. (2003) (143)
Brain oxidative stress in animal models of accelerated aging and the age-related neurodegenerative disorders, Alzheimer's disease and Huntington's disease. (2001) (142)
Active submarine eruption of boninite in the northeastern Lau Basin (2011) (141)
Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: Mitochondrial dysfunction, glutamate dysregulation and impaired protein synthesis (2006) (140)
Methionine residue 35 is critical for the oxidative stress and neurotoxic properties of Alzheimer’s amyloid β-peptide 1–42 (2002) (138)
Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and alpha-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. (2007) (138)
Quantitative proteomics analysis of differential protein expression and oxidative modification of specific proteins in the brains of old mice (2006) (137)
Redox homeostasis and cellular stress response in aging and neurodegeneration. (2010) (136)
Initial results of the rapid response to the 1993 CoAxial event: Relationships between hydrothermal and volcanic processes (1995) (136)
Submarine venting of liquid carbon dioxide on a Mariana Arc volcano (2006) (136)
Alterations in brain antioxidant enzymes and redox proteomic identification of oxidized brain proteins induced by the anti-cancer drug adriamycin: implications for oxidative stress-mediated chemobrain (2010) (135)
Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway (2010) (135)
A neuronal model of Alzheimer's disease: An insight into the mechanisms of oxidative stress–mediated mitochondrial injury (2008) (134)
2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-α release: implications for the reactive oxygen species-mediated mechanisms of chemobrain. (2011) (132)
Alzheimer’s amyloid β-peptide (1–42): involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide (2004) (131)
Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease. (2003) (130)
Apolipoprotein E modulates Alzheimer’s Aβ(1–42)-induced oxidative damage to synaptosomes in an allele-specific manner (2002) (130)
Redox proteomic analysis of carbonylated brain proteins in mild cognitive impairment and early Alzheimer's disease. (2010) (130)
Long-term eruptive activity at a submarine arc volcano (2006) (128)
Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain. (2014) (128)
Proteomic identification of proteins oxidized by Aβ(1–42) in synaptosomes: Implications for Alzheimer's disease (2005) (127)
Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: insights into the progression of this dementing disorder. (2007) (126)
Proteomic analysis of specific brain proteins in aged SAMP8 mice treated with alpha-lipoic acid: implications for aging and age-related neurodegenerative disorders (2005) (126)
Redox regulation of heat shock protein expression by signaling involving nitric oxide and carbon monoxide: relevance to brain aging, neurodegenerative disorders, and longevity. (2006) (125)
Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis. (2005) (123)
Acetylcarnitine and cellular stress response: roles in nutritional redox homeostasis and regulation of longevity genes. (2006) (123)
Distribution, elimination, and biopersistence to 90 days of a systemically introduced 30 nm ceria-engineered nanomaterial in rats. (2012) (121)
The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: It's time for reconciliation (2014) (120)
Protein oxidation and enzyme activity decline in old brown Norway rats are reduced by dietary restriction (1998) (119)
An off-axis hydrothermal vent field near the Mid-Atlantic Ridge at 30 degrees N. (2001) (119)
Glutathione elevation by γ‐glutamyl cysteine ethyl ester as a potential therapeutic strategy for preventing oxidative stress in brain mediated by in vivo administration of adriamycin: Implication for chemobrain (2007) (119)
Antisense directed at the Aβ region of APP decreases brain oxidative markers in aged senescence accelerated mice (2004) (118)
Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease. (2014) (117)
Redox proteomics identification of oxidatively modified brain proteins in inherited Alzheimer's disease: an initial assessment. (2006) (117)
Roles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease (2011) (116)
HIV-dementia, Tat-induced oxidative stress, and antioxidant therapeutic considerations (2005) (114)
Redox regulation in neurodegeneration and longevity: role of the heme oxygenase and HSP70 systems in brain stress tolerance. (2004) (114)
In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe2+/H2O2: Insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders (2006) (114)
Elevation of brain glutathione by γ‐glutamylcysteine ethyl ester protects against peroxynitrite‐induced oxidative stress (2002) (113)
Nutritional approaches to modulate oxidative stress in Alzheimer's disease. (2011) (112)
In vivo protective effects of ferulic acid ethyl ester against amyloid‐beta peptide 1–42‐induced oxidative stress (2006) (112)
Oxidative modification of lipoic acid by HNE in Alzheimer disease brain☆ (2013) (112)
Brain distribution and toxicological evaluation of a systemically delivered engineered nanoscale ceria. (2010) (112)
Beneficial Effects of Dietary Restriction on Cerebral Cortical Synaptic Terminals (2000) (111)
Silica and germanium in Pacific Ocean hydrothermal vents and plumes (1993) (111)
EPR Spin-Trapping Studies of the Hydroxyl Radical Scavenging Activity of Carnosine and Related Dipeptides (1994) (111)
Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain. (2013) (110)
Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment. (2012) (110)
Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome. (2012) (109)
Oxidation of Cytosolic Proteins and Expression of Creatine Kinase BB in Frontal Lobe in Different Neurodegenerative Disorders (1999) (109)
Elevation of mitochondrial glutathione by γ‐glutamylcysteine ethyl ester protects mitochondria against peroxynitrite‐induced oxidative stress (2003) (109)
Effect of Exogenous and Endogenous Antioxidants on 3‐Nitropionic Acid‐Inducedin vivo Oxidative Stress and Striatal Lesions (2000) (108)
Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: implications for Aβ accumulation in AD brain. (2010) (108)
Spin Labeling in Disease (1982) (108)
Proteomics analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by L-acetylcarnitine: insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative stress. (2006) (108)
The expression of key oxidative stress-handling genes in different brain regions in alzheimer’s disease (1998) (107)
β-Amyloid peptide-derived, oxygen-dependent free radicals inhibit glutamate uptake in cultured astrocytes: implications for Alzheimer's disease (1995) (107)
Adriamycin-induced, TNF-alpha-mediated central nervous system toxicity. (2006) (106)
Mutations in amyloid precursor protein and presenilin‐1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid β‐peptide (1–42), H2O2 and kainic acid: implications for Alzheimer's disease (2006) (106)
Redox proteomics in aging rat brain: Involvement of mitochondrial reduced glutathione status and mitochondrial protein oxidation in the aging process (2010) (104)
Chemo brain (chemo fog) as a potential side effect of doxorubicin administration: role of cytokine-induced, oxidative/nitrosative stress in cognitive dysfunction. (2010) (104)
Increased protein and lipid oxidative damage in mitochondria isolated from lymphocytes from patients with Alzheimer's disease: insights into the role of oxidative stress in Alzheimer's disease and initial investigations into a potential biomarker for this dementing disorder. (2011) (104)
Elevated levels of pro-apoptotic p53 and its oxidative modification by the lipid peroxidation product, HNE,in brain from subjects with amnestic mild cognitive impairment and Alzheimer's disease (2008) (103)
Boron and halide systematics in submarine hydrothermal systems: Effects of phase separation and sedimentary contributions (1994) (103)
Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment (2009) (103)
Catalytic biofunctional membranes containing site-specifically immobilized enzyme arrays: a review (2001) (103)
Seafloor deformation and forecasts of the April 2011 eruption at Axial Seamount (2012) (103)
Mass spectrometry and redox proteomics: applications in disease. (2014) (103)
Proteomics-determined differences in the concanavalin-A-fractionated proteome of hippocampus and inferior parietal lobule in subjects with Alzheimer's disease and mild cognitive impairment: implications for progression of AD. (2009) (102)
Protein Levels and Activity of Some Antioxidant Enzymes in Hippocampus of Subjects with Amnestic Mild Cognitive Impairment (2008) (102)
Protein levels of heat shock proteins 27, 32, 60, 70, 90 and thioredoxin-1 in amnestic mild cognitive impairment: An investigation on the role of cellular stress response in the progression of Alzheimer disease (2010) (101)
Short-term molecular-level effects of silver nanoparticle exposure on the earthworm, Eisenia fetida. (2012) (101)
Lipopolysaccharide impairs amyloid beta efflux from brain: altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood–brain barrier (2012) (100)
Amyloid beta-peptide-associated free radical oxidative stress, neurotoxicity, and Alzheimer's disease. (1999) (100)
Biodistribution and oxidative stress effects of a systemically-introduced commercial ceria engineered nanomaterial (2009) (100)
Electron paramagnetic resonance investigations of free radical-induced alterations in neocortical synaptosomal membrane protein infrastructure. (1994) (100)
Redox proteomics: from protein modifications to cellular dysfunction and disease. (2006) (100)
Bilirubin injury to neurons: contribution of oxidative stress and rescue by glycoursodeoxycholic acid. (2008) (100)
Vitamin E is essential for Purkinje neuron integrity (2014) (99)
A link between hyperbilirubinemia, oxidative stress and injury to neocortical synaptosomes (2004) (99)
Spin label study of erythrocyte membrane fluidity in myotonic and Duchenne muscular dystrophy and congenital myotonia (1976) (98)
Role of the proteasome in protein oxidation and neural viability following low‐level oxidative stress (2003) (98)
Proteomic identification of proteins specifically oxidized in Caenorhabditis elegans expressing human Aβ(1–42): Implications for Alzheimer's disease (2006) (97)
Modulation of phospholipid asymmetry in synaptosomal membranes by the lipid peroxidation products, 4-hydroxynonenal and acrolein: implications for Alzheimer's disease (2004) (97)
Redox proteomics. (2012) (97)
Strategy to reduce free radical species in Alzheimer’s disease: an update of selected antioxidants (2015) (97)
Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration (2015) (96)
Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease (2008) (96)
The Expression of Several Mitochondrial and Nuclear Genes Encoding the Subunits of Electron Transport Chain Enzyme Complexes, Cytochrome c Oxidase, and NADH Dehydrogenase, in Different Brain Regions in Alzheimer's Disease (1999) (95)
Alzheimer's amyloid β-peptide associated free radicals increase rat embryonic neuronal polyamine uptake and ornithine decarboxylase activity: protective effect of vitamin E (1999) (95)
Proteomic identification of nitrated brain proteins in amnestic mild cognitive impairment: a regional study (2007) (94)
Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment. (2014) (93)
The Antioxidant Vitamin E Modulates Amyloid β-Peptide-Induced Creatine Kinase Activity Inhibition and Increased Protein Oxidation: Implications for the Free Radical Hypothesis of Alzheimer's Disease (1999) (92)
Role of spermine in amyloid β‐peptide‐associated free radical‐induced neurotoxicity (2001) (91)
Acrolein inhibits NADH-linked mitochondrial enzyme activity: Implications for Alzheimer's disease (2009) (91)
The 2013 SFRBM discovery award: selected discoveries from the butterfield laboratory of oxidative stress and its sequela in brain in cognitive disorders exemplified by Alzheimer disease and chemotherapy induced cognitive impairment. (2014) (90)
Electron spin resonance study of membrane protein alterations in erythrocytes in Huntington's disease (1977) (90)
Quantitative proteomics analysis of phosphorylated proteins in the hippocampus of Alzheimer's disease subjects. (2011) (90)
In vivo administration of D609 leads to protection of subsequently isolated gerbil brain mitochondria subjected to in vitro oxidative stress induced by amyloid beta-peptide and other oxidative stressors: relevance to Alzheimer's disease and other oxidative stress-related neurodegenerative disorders. (2006) (90)
Redox proteomics analysis of brains from subjects with amnestic mild cognitive impairment compared to brains from subjects with preclinical Alzheimer's disease: insights into memory loss in MCI. (2011) (89)
Different Mechanisms of Oxidative Stress and Neurotoxicity for AlzheimersA ‚(1-42) and A‚(25-35) (2001) (89)
Oxidative stress occurs early in Down syndrome pregnancy: A redox proteomics analysis of amniotic fluid (2011) (88)
Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action. (2011) (88)
Antioxidants protect against reactive oxygen species associated with adriamycin-treated cardiomyocytes. (1999) (88)
Redox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down's syndrome and Alzheimer's disease brain. (2014) (88)
Disruption of Thiol Homeostasis and Nitrosative Stress in the Cerebrospinal Fluid of Patients with Active Multiple Sclerosis: Evidence for a Protective Role of Acetylcarnitine (2003) (87)
Alteration of hepatic structure and oxidative stress induced by intravenous nanoceria. (2012) (87)
Methionine-35 of Aβ(1–42): Importance for Oxidative Stress in Alzheimer Disease (2011) (87)
3-Nitropropionic acid induced in vivo protein oxidation in striatal and cortical synaptosomes: insights into Huntington's disease (2000) (87)
Microbial utilization of abiogenic carbon and hydrogen in a serpentinite-hosted system (2012) (87)
Exploring the Submarine Ring of Fire: Mariana Arc - Western Pacific (2007) (86)
Aging‐ and Oxygen‐induced Modifications in Brain Biochemistry and Behavior a (1994) (85)
Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease. (2014) (85)
Preclinical Alzheimer disease: Brain oxidative stress, Aβ peptide and proteomics (2010) (85)
Oxidative and nitrosative modifications of biliverdin reductase-A in the brain of subjects with Alzheimer's disease and amnestic mild cognitive impairment. (2011) (84)
Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm. (2016) (84)
Proteomic analysis of brain proteins in the gracile axonal dystrophy (gad) mouse, a syndrome that emanates from dysfunctional ubiquitin carboxyl‐terminal hydrolase L‐1, reveals oxidation of key proteins (2004) (84)
Substitution of isoleucine-31 by helical-breaking proline abolishes oxidative stress and neurotoxic properties of Alzheimer’s amyloid β-peptide (1–42) (2002) (84)
Oxidative modification of brain proteins in Alzheimer's disease: perspective on future studies based on results of redox proteomics studies. (2012) (83)
Redox regulation of cellular stress response in neurodegenerative disorders. (2006) (83)
Oxidative modification of glutamine synthetase by amyloid beta peptide. (1997) (83)
Oxidative damage in brain from human mutant APP/PS-1 double knock-in mice as a function of age. (2008) (83)
Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment. (2011) (82)
Electron spin resonance studies of membrane proteins in erythrocytes in myotonic muscular dystrophy. (1976) (82)
Aging and caloric restriction affect mitochondrial respiration and lipid membrane status: an electron paramagnetic resonance investigation. (1997) (82)
Rodent Abeta(1-42) exhibits oxidative stress properties similar to those of human Abeta(1-42): Implications for proposed mechanisms of toxicity. (2004) (81)
Peptides and proteins in plasma and cerebrospinal fluid as biomarkers for the prediction, diagnosis, and monitoring of therapeutic efficacy of Alzheimer's disease. (2008) (81)
Role of glycine-33 and methionine-35 in Alzheimer's amyloid beta-peptide 1-42-associated oxidative stress and neurotoxicity. (2002) (81)
Oxidative stress in neurodegenerative disorders. (2006) (81)
Statins more than cholesterol lowering agents in Alzheimer disease: their pleiotropic functions as potential therapeutic targets. (2014) (80)
Doxorubicin-induced elevated oxidative stress and neurochemical alterations in brain and cognitive decline: protection by MESNA and insights into mechanisms of chemotherapy-induced cognitive impairment (“chemobrain”) (2018) (79)
It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease (2016) (79)
High SO2 flux, sulfur accumulation, and gas fractionation at an erupting submarine volcano (2011) (78)
Protection against amyloid beta-peptide (1-42)-induced loss of phospholipid asymmetry in synaptosomal membranes by tricyclodecan-9-xanthogenate (D609) and ferulic acid ethyl ester: implications for Alzheimer's disease. (2005) (78)
Potential in vivo amelioration by N‐acetyl‐L‐cysteine of oxidative stress in brain in human double mutant APP/PS‐1 knock‐in mice: Toward therapeutic modulation of mild cognitive impairment (2010) (78)
The Free Radical Antioxidant Vitamin E Protects Cortical Synaptosomal Membranes from Amyloid β-Peptide(25-35) Toxicity But Not from Hydroxynonenal Toxicity: Relevance to the Free Radical Hypothesis of Alzheimer's Disease (1998) (78)
Temporal and spatial variability of hydrothermal manganese and iron at Cleft segment, Juan de Fuca Ridge (1994) (77)
Ischemia/reperfusion-induced changes in membrane proteins and lipids of gerbil cortical synaptosomes (1995) (77)
Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Abeta region of amyloid precursor protein. (2005) (77)
Oxidative damage in human gingival fibroblasts exposed to cigarette smoke. (2012) (76)
A comparative electron spin resonance study of the erythrocyte membrane in myotonic muscular dystrophy. (1974) (76)
Vitamin E protects against Alzheimer's amyloid peptide (25–35)-induced changes in neocortical synaptosomal membrane lipid structure and composition (1998) (75)
Redox proteomics identification of oxidatively modified proteins in Alzheimer's disease brain and in vivo and in vitro models of AD centered around Abeta(1-42). (2006) (75)
Venting of a Separate CO2-Rich Gas Phase from Submarine Arc Volcanoes (2008) (75)
Proteomics in animal models of Alzheimer's and Parkinson's diseases (2009) (75)
Increased protein oxidation and decreased creatine kinase BB expression and activity after spinal cord contusion injury. (2002) (75)
APP and PS-1 mutations induce brain oxidative stress independent of dietary cholesterol: implications for Alzheimer’s disease (2004) (73)
beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease. (1994) (73)
Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease (2020) (73)
Prevention of Hyperoxia‐Induced Alterations in Synaptosomal Membrane‐Associated Proteins by N‐tert‐Butyl‐α‐Phenylnitrone and 4‐Hydroxy‐2,2,6,6‐Tetramethylpiperidin‐1‐oxyl (Tempol) (1996) (73)
Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone. (1997) (73)
Cholesterol-independent neuroprotective and neurotoxic activities of statins: perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders. (2011) (72)
Effects of oxidative and nitrosative stress in brain on p53 proapoptotic protein in amnestic mild cognitive impairment and Alzheimer disease. (2008) (72)
Glutathionylation of the Pro-apoptotic Protein p53 in Alzheimer’s Disease Brain: Implications for AD Pathogenesis (2009) (72)
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome (2018) (71)
Protective Effect of Carnosine During Nitrosative Stress in Astroglial Cell Cultures (2005) (71)
Interactions Between Carnosine and the Different Redox States of Myoglobin (1995) (71)
Oxidative Stress in HPV-Driven Viral Carcinogenesis: Redox Proteomics Analysis of HPV-16 Dysplastic and Neoplastic Tissues (2012) (70)
Effects of UVB-induced oxidative stress on protein expression and specific protein oxidation in normal human epithelial keratinocytes: a proteomic approach (2010) (70)
Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients. (2015) (70)
Layer-by-layer-assembled microfiltration membranes for biomolecule immobilization and enzymatic catalysis. (2006) (70)
4-Hydroxynonenal oxidatively modifies histones: implications for Alzheimer's disease (2004) (68)
Unconjugated bilirubin differentially affects the redox status of neuronal and astroglial cells (2008) (68)
Spin label and biochemical studies of erythrocyte membranes in Alzheimer's disease (1980) (68)
Vitamin Ε as an Antioxidant/Free Radical Scavenger Against Amyloid β-Peptide-Induced Oxidative Stress in Neocortical Synaptosomal Membranes and Hippocampal Neurons in Culture: Insights into Alzheimer's Disease (1999) (68)
Dietary vitamin D deficiency in rats from middle to old age leads to elevated tyrosine nitration and proteomics changes in levels of key proteins in brain: implications for low vitamin D-dependent age-related cognitive decline. (2013) (68)
Conformational Altered p53 as an Early Marker of Oxidative Stress in Alzheimer's Disease (2012) (68)
Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function. (2006) (68)
Circulating biomarkers of protein oxidation for Alzheimer disease: expectations within limits. (2011) (67)
Apolipoprotein A‐I: Insights from redox proteomics for its role in neurodegeneration (2013) (67)
Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease. (2001) (66)
Oxidative stress and therapeutic approaches in HIV dementia. (2006) (66)
Molecular Chaperones and Their Roles in Neural Cell Differentiation (2002) (66)
A beta (25-35) peptide displays H2O2-like reactivity towards aqueous Fe2+, nitroxide spin probes, and synaptosomal membrane proteins. (1995) (66)
In Vivo Processing of Ceria Nanoparticles inside Liver: Impact on Free-Radical Scavenging Activity and Oxidative Stress. (2014) (66)
Redox proteomics and the dynamic molecular landscape of the aging brain (2014) (65)
Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain. (2012) (65)
Biliverdin reductase‐A: a novel drug target for atorvastatin in a dog pre‐clinical model of Alzheimer disease (2012) (64)
Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice. (2004) (64)
Electron spin resonance studies of erythrocytes from patients with myotonic muscular dystrophy. (1974) (63)
Redox proteomics and amyloid β‐peptide: insights into Alzheimer disease (2018) (63)
A tombstone in Alzheimer's? (1995) (63)
γ‐glutamylcysteine ethyl ester‐induced up‐regulation of glutathione protects neurons against Aβ(1–42)‐mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease (2005) (63)
Electron spin resonance investigations of membrane proteins in erythrocytes in muscle diseases. Duchenne and myotonic muscular dystrophy and congenital myotonia. (1977) (63)
Lymphocyte mitochondria: toward identification of peripheral biomarkers in the progression of Alzheimer disease. (2013) (62)
The Triangle of Death in Alzheimer's Disease Brain: The Aberrant Cross-Talk Among Energy Metabolism, Mammalian Target of Rapamycin Signaling, and Protein Homeostasis Revealed by Redox Proteomics. (2017) (62)
Decreased expression and increased oxidation of plasma haptoglobin in Alzheimer disease: Insights from redox proteomics. (2012) (62)
Aberrant protein phosphorylation in Alzheimer disease brain disturbs pro-survival and cell death pathways. (2016) (61)
Role of phenylalanine 20 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity. (2004) (61)
Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease (2015) (60)
Redox proteomic identification of oxidized cardiac proteins in adriamycin-treated mice. (2006) (60)
Adriamycin-induced changes of creatine kinase activity in vivo and in cardiomyocyte culture. (1999) (59)
Disruption of the hippocampal and hypothalamic blood–brain barrier in a diet-induced obese model of type II diabetes: prevention and treatment by the mitochondrial carbonic anhydrase inhibitor, topiramate (2019) (59)
Glutamine Synthetase‐Induced Enhancement of β‐Amyloid Peptide Aβ(1–40) Neurotoxicity Accompanied by Abrogation of Fibril Formation and Aβ Fragmentation (1996) (59)
Oxidative stress and toxicity induced by the nucleoside reverse transcriptase inhibitor (NRTI)—2′,3′-dideoxycytidine (ddC): Relevance to HIV-dementia (2007) (59)
Polythiol-functionalized alumina membranes for mercury capture (2005) (58)
ESR studies of the erythrocyte membrane skeletal protein network: influence of the state of aggregation of spectrin on the physical state of membrane proteins, bilayer lipids, and cell surface carbohydrates. (1985) (58)
Acrolein induces selective protein carbonylation in synaptosomes (2007) (58)
Proteomic identification of nitrated brain proteins in traumatic brain‐injured rats treated postinjury with gamma‐glutamylcysteine ethyl ester: Insights into the role of elevation of glutathione as a potential therapeutic strategy for traumatic brain injury (2009) (57)
Seismic precursors and magma ascent before the April 2011 eruption at Axial Seamount (2012) (57)
Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease (2018) (56)
In vivo protection by the xanthate tricyclodecan-9-yl-xanthogenate against amyloid β-peptide (1–42)-induced oxidative stress (2006) (55)
Rat brain pro-oxidant effects of peripherally administered 5 nm ceria 30 days after exposure. (2012) (55)
Plausible biochemical mechanisms of chemotherapy-induced cognitive impairment ("chemobrain"), a condition that significantly impairs the quality of life of many cancer survivors. (2019) (55)
Differential expression and redox proteomics analyses of an Alzheimer disease transgenic mouse model: effects of the amyloid-β peptide of amyloid precursor proteinΞ (2011) (55)
In vivo modulation of rodent glutathione and its role in peroxynitrite-induced neocortical synaptosomal membrane protein damage. (1999) (54)
Vitamin D deficiency and Alzheimer disease: Common links (2015) (54)
Proteomics for the identification of specifically oxidized proteins in brain: Technology and application to the study of neurodegenerative disorders (2003) (53)
Variability in Microbial Communities in Black Smoker Chimneys at the NW Caldera Vent Field, Brothers Volcano, Kermadec Arc (2009) (53)
Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and Duchenne muscular dystrophy (1980) (53)
Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1/BVR-a system: insights for transition to Alzheimer's disease. (2015) (53)
Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells. (2017) (52)
Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice: insights into mechanisms of familial Parkinson's disease (2015) (52)
Elevated glutathione as a therapeutic strategy in Alzheimer's disease (2002) (52)
Amyloid β‐Peptide Effects on Synaptosomes from Apolipoprotein E‐Deficient Mice (2000) (52)
Cell Cycle Proteins in Brain in Mild Cognitive Impairment: Insights into Progression to Alzheimer Disease (2012) (51)
Increased O-GlcNAc levels correlate with decreased O-GlcNAcase levels in Alzheimer disease brain. (2014) (51)
Vitamin E as an antioxidant/free radical scavenger against amyloid beta-peptide-induced oxidative stress in neocortical synaptosomal membranes and hippocampal neurons in culture: insights into Alzheimer's disease. (1999) (50)
Aging in a dish: Age‐dependent changes of neuronal survival, protein oxidation, and creatine kinase BB expression in long‐term hippocampal cell culture (1999) (50)
Increased sodium plus potassium adenosine triphosphatase activity in erythrocyte membranes in Huntington's disease (1978) (50)
D609 inhibits ionizing radiation-induced oxidative damage by acting as a potent antioxidant. (2001) (50)
Insufficient Sun Exposure Has Become a Real Public Health Problem (2020) (49)
Effect of botanical extracts containing carnosic acid or rosmarinic acid on learning and memory in SAMP8 mice (2016) (49)
Redox proteomics: understanding oxidative stress in the progression of age-related neurodegenerative disorders (2008) (49)
Proteomic identification of differentially expressed proteins in the aging murine olfactory system and transcriptional analysis of the associated genes (2005) (49)
Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. (2015) (49)
Methamphetamine toxicity is attenuated in mice that overexpress human manganese superoxide dismutase (2000) (49)
Striatal Damage and Oxidative Stress Induced by the Mitochondrial Toxin Malonate Are Reduced in Clorgyline-Treated Rats and MAO-A Deficient Mice (2004) (48)
Oxidative Stress in Synaptosomal Proteins from Mutant Presenilin-1 Knock-in Mice: Implications for Familial Alzheimer's Disease (2002) (48)
Electron spin resonance and biochemical studies of the interaction of the polyamine, spermine, with the skeletal network of proteins in human erythrocyte membranes. (1988) (48)
Mrp1 Localization and Function in Cardiac Mitochondria after Doxorubicin (2009) (47)
Tumor necrosis factor alpha–mediated nitric oxide production enhances manganese superoxide dismutase nitration and mitochondrial dysfunction in primary neurons: an insight into the role of glial cells (2008) (47)
Structural and functional changes in proteins induced by free radical-mediated oxidative stress and protective action of the antioxidants N-tert-butyl-alpha-phenylnitrone and vitamin E. (1998) (47)
Regional Expression of Key Cell Cycle Proteins in Brain from Subjects with Amnestic Mild Cognitive Impairment (2007) (47)
Pharmacologists and Alzheimer disease therapy: to boldly go where no scientist has gone before (2011) (47)
γ‐Glutamylcysteine ethyl ester protection of proteins from Aβ(1–42)‐mediated oxidative stress in neuronal cell culture: A proteomics approach (2005) (47)
Protective effect of D609 against amyloid‐beta1–42‐induced oxidative modification of neuronal proteins: Redox proteomics study (2006) (46)
Proteomics analysis of human astrocytes expressing the HIV protein Tat. (2005) (46)
Effects of mitochondrial respiratory stimulation on membrane lipids and proteins: an electron paramagnetic resonance investigation. (1998) (45)
In vivo protection of synaptosomes from oxidative stress mediated by Fe2+/H2O2 or 2,2-azobis-(2-amidinopropane) dihydrochloride by the glutathione mimetic tricyclodecan-9-yl-xanthogenate. (2005) (45)
Temporal relations among amyloid β-peptide-induced free-radical oxidative stress, neuronal toxicity, and neuronal defensive responses (1998) (45)
HO-1/BVR-a system analysis in plasma from probable Alzheimer's disease and mild cognitive impairment subjects: a potential biochemical marker for the prediction of the disease. (2012) (45)
Proteomic analysis of brain proteins in APP/PS‐1 human double mutant knock‐in mice with increasing amyloid β‐peptide deposition: Insights into the effects of in vivo treatment with N‐acetylcysteine as a potential therapeutic intervention in mild cognitive impairment and Alzheimer's disease (2011) (45)
Redox proteomics analyses of the influence of co-expression of wild-type or mutated LRRK2 and Tau on C. elegans protein expression and oxidative modification: relevance to Parkinson disease. (2012) (44)
Amyloid β-peptide inhibits Na+-dependent glutamate uptake (1999) (44)
Long-term ethanol administration enhances age-dependent modulation of redox state in different brain regions in the rat: protection by acetyl carnitine. (2002) (44)
Amyloid beta-peptide spin trapping. I: Peptide enzyme toxicity is related to free radical spin trap reactivity. (1995) (44)
Protein Carbonyl Levels—An Assessment of Protein Oxidation (2003) (44)
Oxidative stress in the aging murine olfactory bulb: Redox proteomics and cellular localization (2007) (43)
Protective effect of ferulic acid ethyl ester against oxidative stress mediated by UVB irradiation in human epidermal melanocytes (2009) (43)
Scanning electron microscopy studies of erythrocytes in Huntington's disease. (1977) (43)
Effects of apolipoprotein E on the human immunodeficiency virus protein tat in neuronal cultures and synaptosomes (2004) (43)
The triangle of death of neurons: Oxidative damage, mitochondrial dysfunction, and loss of choline-containing biomolecules in brains of mice treated with doxorubicin. Advanced insights into mechanisms of chemotherapy induced cognitive impairment ("chemobrain") involving TNF-α. (2019) (42)
Amyloid beta-peptide (1-40)-mediated oxidative stress in cultured hippocampal neurons. Protein carbonyl formation, CK BB expression, and the level of Cu, Zn, and Mn SOD mRNA. (1998) (42)
Antioxidant activity of the organotellurium compound 3-[4-(N,N-dimethylamino)benzenetellurenyl]propanesulfonic acid against oxidative stress in synaptosomal membrane systems and neuronal cultures (2001) (42)
Increase in Mrp1 expression and 4-hydroxy-2-nonenal adduction in heart tissue of Adriamycin-treated C57BL/6 mice (2006) (42)
Permeability and Separation Characteristics of Polypeptide-Functionalized Polycarbonate Track-Etched Membranes (2004) (42)
Observations of manganese and iron at the CoAxial Seafloor Eruption Site, Juan de Fuca Ridge (1995) (42)
Open peer commentary In vitro and in vivo oxidative stress associated with Alzheimer's amyloid b-peptide (1- 42) (1999) (41)
In vitro and in vivo neuroprotection by γ-glutamylcysteine ethyl ester against MPTP: Relevance to the role of glutathione in Parkinson's disease (2006) (41)
Substitution of isoleucine-31 by helical-breaking proline abolishes oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide. (2002) (41)
Prevention of ischemia/reperfusion-induced alterations in synaptosomal membrane-associated proteins and lipids by N-tert-butyl-α-phenylnitrone and difluoromethylornithine (1995) (41)
A model for beta-amyloid aggregation and neurotoxicity based on the free radical generating capacity of the peptide: implications of "molecular shrapnel" for Alzheimer's disease. (1995) (41)
Membrane protein alterations in rodent erythrocytes and synaptosomes due to aging and hyperoxia. (1995) (41)
Lectin‐affinity chromatography brain glycoproteomics and Alzheimer disease: Insights into protein alterations consistent with the pathology and progression of this dementing disorder (2011) (41)
Proteomic identification of specifically carbonylated brain proteins in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice model of Alzheimer disease as a function of age. (2011) (41)
Submarine Hydrothermal Activity and Gold-Rich Mineralization at Brothers Volcano, Southern Kermadec Arc, New Zealand (2006) (40)
Oxidative Damage in Rat Brain During Aging: Interplay Between Energy and Metabolic Key Target Proteins (2010) (40)
Age-related loss of phospholipid asymmetry in APP NLh /APP NLh x PS-1 P264L /PS-1 P264L human double mutant knock-in mice: Relevance to Alzheimer disease (2010) (40)
Helium isotope, C/3He, and Ba‐Nb‐Ti signatures in the northern Lau Basin: Distinguishing arc, back‐arc, and hotspot affinities (2015) (40)
Variations in water‐column ³He/heat ratios associated with the 1993 CoAxial event, Juan de Fuca Ridge (1995) (40)
Extracellular Vesicles Released by Cardiomyocytes in a Doxorubicin-Induced Cardiac Injury Mouse Model Contain Protein Biomarkers of Early Cardiac Injury (2017) (39)
Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease (2019) (39)
The wheat germ agglutinin‐fractionated proteome of subjects with Alzheimer's disease and mild cognitive impairment hippocampus and inferior parietal lobule: Implications for disease pathogenesis and progression (2010) (39)
Oxidative Stress and Proteostasis Network: Culprit and Casualty of Alzheimer’s-Like Neurodegeneration (2014) (38)
Amyloid beta-peptide spin trapping. II: Evidence for decomposition of the PBN spin adduct. (1995) (38)
Superoxide induces protein oxidation in plasma and TNF-α elevation in macrophage culture: Insights into mechanisms of neurotoxicity following doxorubicin chemotherapy. (2015) (38)
Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome (2019) (38)
α-1-Antichymotrypsin interaction with Aβ (1–40) inhibits fibril formation but does not affect the peptide toxicity (1996) (38)
Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome (2020) (38)
The hydrophobic environment of Met35 of Alzheimer's Aβ(1–42) is important for the neurotoxic and oxidative properties of the peptide (2002) (37)
Activity and abundance of denitrifying bacteria in the subsurface biosphere of diffuse hydrothermal vents of the Juan de Fuca Ridge (2012) (37)
Enhancement of β‐Amyloid Peptide Aβ(1–40)‐Mediated Neurotoxicity by Glutamine Synthetase (1995) (37)
Lentivirus Infection Causes Neuroinflammation and Neuronal Injury in Dorsal Root Ganglia: Pathogenic Effects of STAT-1 and Inducible Nitric Oxide Synthase1 (2005) (37)
Effect of lipopolysaccharide on the physical conformation of the erythrocyte cytoskeletal proteins. (1995) (37)
HNE-modified proteins in Down syndrome: Involvement in development of Alzheimer disease neuropathology. (2017) (37)
Low molecular weight thiol amides attenuate MAPK activity and protect primary neurons from Aβ(1–42) toxicity (2006) (37)
Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: a proteomics study. (2013) (37)
Targeting Mitochondria in Alzheimer Disease: Rationale and Perspectives (2019) (37)
Plasma TNF-α and Soluble TNF Receptor Levels after Doxorubicin with or without Co-Administration of Mesna—A Randomized, Cross-Over Clinical Study (2015) (36)
Selective spin labeling of sialic acid residues of glycoproteins and glycolipids in erythrocyte membranes: a novel method to study cell surface interactions. (1980) (36)
Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling. (2016) (36)
Deep submergence synergy: Alvin and ABE explore the gálapagos rift at 86°W (2003) (36)
Huntington's disease: a generalized membrane defect. (1981) (36)
Submarine magmatic-hydrothermal systems at the monowai volcanic center, Kermadec Arc (2012) (36)
Biological and synthetic membranes (1989) (35)
Electron spin resonance studies of erythrocyte membranes in muscular dystrophy (1977) (35)
Effect of 2-cyclohexene-1-one-induced glutathione diminution on ischemia/reperfusion-induced alterations in the physical state of brain synaptosomal membrane proteins and lipids (1997) (35)
Redox proteomics in some age-related neurodegenerative disorders or models thereof (2006) (35)
Identification of the oxidative stress proteome in the brain. (2011) (34)
Quantitative phosphoproteomic analyses of the inferior parietal lobule from three different pathological stages of Alzheimer's disease. (2015) (34)
Biofunctional membranes: an EPR study of active site structure and stability of papain non-covalently immobilized on the surface of modified poly(ether) sulfone membranes through the avidin-biotin linkage (1996) (34)
S100A4 alters metabolism and promotes invasion of lung cancer cells by up-regulating mitochondrial complex I protein NDUFS2 (2019) (33)
Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease. (2018) (33)
Disturbance of redox homeostasis in Down Syndrome: Role of iron dysmetabolism. (2018) (32)
Mitochondrial Oxidative and Nitrosative Stress and Alzheimer Disease (2020) (32)
Brain lipid peroxidation and alzheimer disease: Synergy between the Butterfield and Mattson laboratories (2020) (32)
Geological, chemical, and biological evidence for recent volcanism at 17.5°S: East Pacific Rise (1998) (32)
Interaction of hemin with erythrocyte membranes: alterations in the physical state of the major sialoglycoprotein. (1989) (32)
Adriamycin induces protein oxidation in erythrocyte membranes. (1998) (32)
The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease. (2021) (32)
Lack of p53 decreases basal oxidative stress levels in the brain through upregulation of thioredoxin-1, biliverdin reductase-A, manganese superoxide dismutase, and nuclear factor kappa-B. (2012) (31)
Spin Labeling of Membrane Proteins in Mammalian Brain Synaptic Plasma Membranes: Partial Characterization (1992) (31)
Proteomics analysis in Alzheimer's disease: new insights into mechanisms of neurodegeneration. (2004) (31)
Activation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype. (2016) (31)
In vivo amelioration of adriamycin induced oxidative stress in plasma by gamma-glutamylcysteine ethyl ester (GCEE). (2009) (31)
Acute treatment with doxorubicin affects glutamate neurotransmission in the mouse frontal cortex and hippocampus (2017) (31)
Proteomic analysis of oxidatively modified proteins in Alzheimer's disease brain: insights into neurodegeneration. (2003) (31)
Electron spin resonance, hematological, and deformability studies of erythrocytes from patients with Huntington's disease. (1979) (31)
The identification of protein biomarkers for oxidative stress in Down syndrome (2011) (30)
Proteomics identification of carbonylated and HNE-bound brain proteins in Alzheimer's disease. (2009) (29)
Alternations in lipid membrane fluidity and the physical state of cell-surface sialic acid in zinc-deficient rat erythrocyte ghosts. (1987) (29)
Biofunctional membranes Part IV. Active-site structure and stability of an immobilized enzyme, papain, on modified polysulfone membranes studied by electron paramagnetic resonance and kinetics (1994) (29)
Redox Proteomics: A Key Tool for New Insights into Protein Modification with Relevance to Disease. (2017) (29)
mTOR in Alzheimer Disease and Its Earlier Stages: Links to Oxidative Damage in the Progression of this Dementing Disorder. (2021) (29)
The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal (2012) (29)
Rat hippocampal responses up to 90 days after a single nanoceria dose extends a hierarchical oxidative stress model for nanoparticle toxicity (2014) (29)
Menadione-induced cytotoxicity effects on human erythrocyte membranes studied by electron paramagnetic resonance. (1994) (29)
Identification of 3-nitrotyrosine-modified brain proteins by redox proteomics. (2008) (28)
Perspectives on Oxidative Stress in Alzheimer's Disease and Predictions of Future Research Emphases. (2018) (28)
Electron spin resonance studies of fatty acid-induced alterations in membrane fluidity in cultured endothelial cells. (1995) (28)
Alterations of some membrane transport proteins in Alzheimer's disease: role of amyloid beta-peptide. (2008) (28)
Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease. (2018) (28)
Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer’s disease pathology (2017) (28)
beta-Amyloid peptide-derived, oxygen-dependent free radicals inhibit glutamate uptake in cultured astrocytes: implications for Alzheimer's disease. (1995) (28)
Insulin resistance in Alzheimer disease: Is heme oxygenase-1 an Achille's heel? (2015) (27)
Flat‐sheet and hollow fiber membrane bioreactors: A study of the kinetics and active site conformational changes of immobilized papain including sorption studies of reaction constituents (1995) (27)
Amyloid beta-peptide effects on synaptosomes from apolipoprotein E-deficient mice. (2000) (27)
Slot-blot analysis of 3-nitrotyrosine-modified brain proteins. (2008) (27)
Proteomic analysis of oxidatively modified proteins induced by the mitochondrial toxin 3-nitropropionic acid in human astrocytes expressing the HIV protein tat. (2005) (26)
Proteomics analysis of protein expression and specific protein oxidation in human papillomavirus transformed keratinocytes upon UVB irradiation (2009) (26)
Opiate receptor binding properties of morphine-, dihydromorphine-, and codeine 6-O-sulfate ester congeners. (2006) (26)
Oxidative Stress and Biomaterials (2016) (26)
In Vitro and in vivo Protein Oxidation Induced by Alzheimer's Disease Amyloid β‐Peptide (1–42) (1999) (26)
Principles of biological membrane structure: Alteration of the physical state of one side of the membrane by modulation of the physical state of the op☆ (1990) (26)
Proteomic identification of oxidatively-modified proteins in Alzheimer's disease brain: creatine kinase BB, glutamine synthetase and ubiquitin carboxy-terminal hydroalse (2002) (25)
Controlled curcumin release via conjugation into PBAE nanogels enhances mitochondrial protection against oxidative stress. (2016) (25)
Persistent Hepatic Structural Alterations Following Nanoceria Vascular Infusion in the Rat (2014) (25)
Do proteomics analyses provide insights into reduced oxidative stress in the brain of an Alzheimer disease transgenic mouse model with an M631L amyloid precursor protein substitution and thereby the importance of amyloid-beta-resident methionine 35 in Alzheimer disease pathogenesis? (2012) (25)
New insights into membrane science and technology : polymeric and biofunctional membranes (2003) (25)
Poly-ubiquitin profile in Alzheimer disease brain (2018) (25)
mTOR Inhibitor Everolimus in Regulatory T Cell Expansion for Clinical Application in Transplantation (2019) (23)
An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach. (2014) (23)
Gamma-glutamylcysteine ethyl ester-induced up-regulation of glutathione protects neurons against Abeta(1-42)-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. (2005) (23)
Erythrocyte membrane alterations in Huntington disease: Effects of γ‐aminobutyric acid (1978) (22)
Communication between the Maternal Testa and the Embryo and/or Endosperm Affect Testa Attributes in Tomato1[w] (2003) (22)
Evidence for a membrane surface defect in erythrocytes in Huntington's disease. (1980) (22)
Effects of phytohaemagglutinin, wheat-germ agglutinin, and concanavalin-A on the physical state of sialic acid and membrane proteins in human erythrocyte ghosts: a spin label study. (1982) (22)
A seismic swarm and regional hydrothermal and hydrologic perturbations: The northern Endeavour segment, February 2005 (2010) (22)
Sorafenib and FH535 in combination act synergistically on hepatocellular carcinoma by targeting cell bioenergetics and mitochondrial function. (2017) (22)
Original Contribution Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice—A model of familial amyotrophic lateral sclerosis (2005) (22)
Myotonic muscular dystrophy Time-dependent alterations in erythrocyte membrane fluidity (1981) (22)
Spin Labeling and Kinetic Studies of a Membrane‐Immobilized Proteolytic Enzyme (1992) (21)
α1-Antichymotrypsin interaction with Aβ(1–42) does not inhibit fibril formation but attenuates the peptide toxicity (1996) (21)
A Recent Volcanic Eruption Discovered on the Central Mariana Back-Arc Spreading Center (2018) (21)
Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: a harmful synergistic path in Down syndrome. (2021) (21)
Structural and enzymatic characterizations of papain immobilized onto vinyl alcohol/vinyl butyral copolymer membrane (1992) (21)
Tuning of the pro-oxidant and antioxidant activity of trolox through the controlled release from biodegradable poly(trolox ester) polymers. (2011) (21)
Oxidative Stress in Alzheimer Disease: Synergy Between the Butterfield and Markesbery Laboratories (2011) (20)
Lipid peroxidation and tyrosine nitration in traumatic brain injury: Insights into secondary injury from redox proteomics (2016) (20)
Abundance and Distribution of Hydrothermal Chimneys and Mounds on the Endeavour Ridge Determined by 1-m Resolution AUV Multibeam Mapping Surveys (2008) (20)
Doxorubicin-induced thymus senescence. (2010) (20)
Acetylcarnitine increases membrane cytoskeletal protein-protein interactions. (1993) (20)
Amyloid beta-peptide inhibits Na+-dependent glutamate uptake. (1999) (20)
Alzheimer’s β-Amyloid Peptide and Free Radical Oxidative Stress (2002) (20)
5-Aminosalicylic Acid Protection against Oxidative Damage to Synaptosomal Membranes by Alkoxyl Radicals In Vitro (2004) (20)
β-amyloid-Derived Free Radical Oxidation: A Fundamental Process in Alzheimers Disease (1996) (20)
Involvement of stat3 in mouse brain development and sexual dimorphism: A proteomics approach (2010) (20)
Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53 (2015) (19)
Redox proteomics studies of in vivo amyloid beta‐peptide animal models of Alzheimer's disease: Insight into the role of oxidative stress (2008) (19)
6 Aging and Oxidative Stress Response in the CNS (2008) (19)
Increased chloride transport in erythrocytes in Huntington's disease. (1980) (19)
Research report Proteomic identification of proteins oxidized by Ah(1-42) in synaptosomes: Implications for Alzheimer's disease (2005) (19)
Alteration of the erythrocyte membrane via enzymatic degradation of ankyrin (band 2.1): subcellular surgery characterized by EPR spectroscopy. (1993) (19)
In vitro and in vivo neuroprotection by gamma-glutamylcysteine ethyl ester against MPTP: relevance to the role of glutathione in Parkinson's disease. (2006) (19)
Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: Novel hints on immunosenescence and biomarker detection (2018) (18)
Lack of p53 Affects the Expression of Several Brain Mitochondrial Proteins: Insights from Proteomics into Important Pathways Regulated by p53 (2012) (18)
Neurotoxicity and oxidative stress in D1M-substituted Alzheimer's Aβ(1-42): relevance to N-terminal methionine chemistry in small model peptides (2005) (18)
Coenzyme Q10 and cognition in atorvastatin treated dogs (2011) (18)
Electron spin resonance (ESR) studies of skeletal protein interactions in human erythrocyte membranes exposed to polyanions and in membranes prepared from inositol hexaphosphate (IHP)-incorporated low-affinity erythrocytes. (1987) (18)
Spin label studies of human erythrocyte membranes in aging. (1982) (17)
3-O-Acetylmorphine-6-O-sulfate: A potent, centrally acting morphine derivative (1996) (17)
INDUCED ALTERATIONS IN THE PHYSICAL STATE OF SIALIC ACID AND MEMBRANE PROTEINS IN HUMAN ERYTHROCYTE GHOSTS: IMPLICATIONS FOR THE TOPOLOGY OF THE MAJOR SIALOGLYCOPROTEIN * (1983) (17)
3–Nitropropionic Acid–Induced Changes in Bilayer Fluidity in Synaptosomal Membranes: Implications for Huntington's Disease (2002) (17)
alpha-1-antichymotrypsin interaction with A beta (1-40) inhibits fibril formation but does not affect the peptide toxicity. (1996) (17)
Clinical implications from proteomic studies in neurodegenerative diseases: lessons from mitochondrial proteins (2016) (17)
Metabolic clues to salubrious longevity in the brain of the longest‐lived rodent: the naked mole‐rat (2015) (17)
Kinetics and Active Fraction Determination of a Protease Enzyme Immobilized on Functionalized Membranes: Mathematical Modeling and Experimental Results (1998) (17)
Glutamine synthetase-induced enhancement of beta-amyloid peptide A beta (1-40) neurotoxicity accompanied by abrogation of fibril formation and A beta fragmentation. (1996) (17)
Increased formation of short-chain organic acids after chronic ethanol administration and its interaction with the carnitine pool in rat. (2004) (16)
The role of charge in the toxicity of polymer-coated cerium oxide nanomaterials to Caenorhabditis elegans. (2017) (16)
Erythrocyte membrane fluidity in chicken muscular dystrophy. (1978) (16)
Experimental research on nitric oxide and the therapy of Alzheimer disease: a challenging bridge. (2011) (16)
Formation of a protein-bound pyrazinium free radical cation during glycation of histone H1. (2000) (16)
Detection of carbonylated proteins in two-dimensional sodium dodecyl sulfate polyacrylamide gel electrophoresis separations. (2008) (16)
Structure-activity investigation of the alteration of the physical state of the skeletal network of proteins in human erythrocyte membranes induced by 9-amino-1,2,3,4-tetrahydroacridine. (1990) (15)
Active site structure and stability of the thiol protease papain studied by electron paramagnetic resonance employing a methanethiosulfonate spin label. (1994) (15)
Altered Metabolism in Alzheimer Disease Brain: Role of Oxidative Stress. (2021) (15)
Loss of CLN3, the gene mutated in juvenile neuronal ceroid lipofuscinosis, leads to metabolic impairment and autophagy induction in retina pigment epithelium. (2020) (15)
Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender: Relevance to Parkinson disease. (2019) (15)
Biomarkers of Oxidative Stress in Neurodegenerative Diseases (2013) (15)
Extracellular vesicle-mediated macrophage activation: An insight into the mechanism of thioredoxin-mediated immune activation (2019) (15)
Effects of dehydroabietic acid on the physical state of cytoskeletal proteins and the lipid bilayer of erythrocyte membranes. (1994) (15)
Effect of endotoxin on lipid order and motion in erythrocyte membranes. (1994) (14)
Involvement of PI 3 K / PKG / ERK 1 / 2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and α-lipoic acid against HNE-mediated oxidative stress and neurotoxicity : Implications for Alzheimer ' s disease (2007) (14)
The BACH1/Nrf2 Axis in Brain in Down Syndrome and Transition to Alzheimer Disease-Like Neuropathology and Dementia (2020) (14)
Chronic PERK induction promotes Alzheimer-like neuropathology in Down syndrome: Insights for therapeutic intervention (2020) (14)
Methylmalonate-induced seizures are attenuated in inducible nitric oxide synthase knockout mice (2009) (14)
Autoantibodies Profile in Matching CSF and Serum from AD and aMCI patients: Potential Pathogenic Role and Link to Oxidative Damage. (2016) (14)
Electron paramagnetic resonance studies of the effects of methoxyacetic acid, a teratologic toxin, on human erythrocyte membranes. (1993) (14)
Optimization of covalently coupling enzymes to polymeric membranes: EPR studies of papain (1993) (14)
Membrane-altering effects of velnacrine and N-methylacridinium: relevance to tacrine and Alzheimer's disease. (1992) (13)
Redox Proteomics: A New Approach to Investigate Oxidative Stress in Alzheimer's Disease (2006) (13)
The pyrrolopyrimidine U101033E is a potent free radical scavenger and prevents Fe(II)-induced lipid peroxidation in synaptosomal membranes. (2000) (13)
Lipid Specific Spin-Labeling of Erythrocyte Membranes: Development and Characterization of a new Labeling Procedure for a Cationic Spin Label, CAT-16 (1988) (13)
Electron spin resonance investigation of the interaction of the anion and glucose transport inhibitor, p-azidobenzylphlorizin, with the human red cell membrane. (1989) (13)
Atorvastatin and Aβ(1–40): Not as Simple as Cholesterol Reduction in Brain and Relevance to Alzheimer Disease (2011) (13)
Microdose Lithium NP03 Diminishes Pre-Plaque Oxidative Damage and Neuroinflammation in a Rat Model of Alzheimer's-like Amyloidosis. (2018) (13)
Mapping AUV Survey of Axial Seamount (2006) (12)
CHAPTER 4 – The Relationship of Membrane Fluidity to Degenerative Muscular Diseases (1985) (12)
Detection of 4-hydroxy-2-nonenal- and 3-nitrotyrosine-modified proteins using a proteomics approach. (2009) (12)
Wild type but not mutant APP is involved in protective adaptive responses against oxidants (2010) (12)
Serial Review : Causes and Consequences of Oxidative Stress in Alzheimer ’ s Disease (2002) (11)
Radical decay kinetics in ferrocytochrome c model membranes. A spin label study. (1975) (11)
Hydroacoustic, Seismic, and Bathymetric Observations of the 2014 Submarine Eruption at Ahyi Seamount, Mariana Arc (2019) (11)
Alpha 1-antichymotrypsin interaction with A beta (1-42) does not inhibit fibril formation but attenuates the peptide toxicity. (1996) (11)
Enhancement of the Yu and Ledeen gas-liquid chromatographic method for sialic acid estimation: use of methane chemical ionization mass fragmentography. (1980) (11)
Deep-Sea Volcanic Eruptions Create Unique Chemical and Biological Linkages Between the Subsurface Lithosphere and the Oceanic Hydrosphere (2018) (10)
Antioxidant activity of X-34 in synaptosomal and neuronal systems (2003) (10)
Polyubiquitinylation Profile in Down Syndrome Brain Before and After the Development of Alzheimer Neuropathology. (2017) (10)
Biofunctional Membranes (1996) (10)
Electron paramagnetic resonance spin label titration: a novel method to investigate random and site-specific immobilization of enzymes onto polymeric membranes with different properties (2002) (10)
Enhancement of beta-amyloid peptide A beta(1-40)-mediated neurotoxicity by glutamine synthetase. (1995) (10)
Electron spin resonance studies of the effects of naturally-occurring excitotoxic amino acid analogues on the physical state of membrane proteins in human erythrocytes. (1981) (10)
The alteration of membrane proteins in human erythrocyte membranes induced by quinolinic acid, an endogenous neurotoxin. Correlation of effect with structure. (1984) (10)
Antioxidants and antioxidant treatment in disease. (2012) (9)
Original Contribution In vivo protection of synaptosomes from oxidative stress mediated by Fe 2+ /H 2 O 2 or 2,2-azobis-(2-amidinopropane) dihydrochloride by the glutathione mimetic tricyclodecan-9-yl-xanthogenate (2005) (9)
Evidence for an Altered Physical State of Membrane Proteins in Erythrocytes in Friedreich's Ataxia (1979) (9)
Tuning of the Pro-oxidant and Antioxidant Activity of Trolox Through the Controlled Release from Biodegradable Poly(trolox ester) Polymers (2010) (9)
Spin-labelling studies of the interaction of 9-amino-1,2,3,4-tetrahydroacridine (THA), a proposed drug for the treatment of Alzheimer's disease, with erythrocyte membranes. (1990) (9)
Proteomics identification of oxidatively modified proteins in brain. (2009) (9)
Evidence for an increased rate of choline efflux across erythrocyte membranes in Alzheimer's disease (1985) (9)
Selective labeling of membrane protein sulfhydryl groups with methanethiosulfonate spin label. (1995) (9)
Comparative proteomic analyses of the parietal lobe from rhesus monkeys fed a high-fat/sugar diet with and without resveratrol supplementation, relative to a healthy diet: Insights into the roles of unhealthy diets and resveratrol on function. (2017) (9)
Identification of AGE-modified proteins in SH-SY5Y and OLN-93 Cells (2006) (9)
Spectroscopic methods in degenerative neurological diseases. (1986) (9)
Antioxidant Agents in Alzheimers Disease (2008) (9)
Hydrogen and thiosulfate limits for growth of a thermophilic, autotrophic Desulfurobacterium species from a deep-sea hydrothermal vent. (2016) (8)
Lack of p 53 Decreases Basal Oxidative Stress Levels in the Brain Through Upregulation of Thioredoxin-1 , Biliverdin Reductase-A , Manganese Superoxide Dismutase , and Nuclear Factor Kappa-B (2012) (8)
Posteruption Enhancement of Hydrothermal Activity: A 33‐Year, Multieruption Time Series at Axial Seamount (Juan de Fuca Ridge) (2019) (8)
Membrane processes associated with the osmotic-pulse incorporation of inositol hexaphosphate. (1990) (8)
Spotlight: Axial Seamount (2010) (8)
Global effects of adriamycin treatment on mouse splenic protein levels. (2012) (8)
2,2,6,6-Tetramethyl-4-Amino[d17]Piperidine-15N-1-OXYL as a Spin Label For Cell Surface Carbohydrates (1985) (8)
Corrigendum to “Lipopolysaccharide alters the blood–brain barrier transport of amyloid b protein: A mechanism for inflammation in the progression of Alzheimer’s disease” [Brain Behav. Immun. 23 (2009) 507–517] (2011) (8)
Structural alterations in synaptosomal membrane-associated proteins and lipids by transient middle cerebral artery occlusion in the cat (1995) (8)
Redox Proteomics in Human Biofluids: Sample Preparation, Separation and Immunochemical Tagging for Analysis of Protein Oxidation. (2016) (8)
Unique Solid Phase Microextraction Sampler Reveals Distinctive Biogeochemical Profiles among Various Deep-Sea Hydrothermal Vents (2020) (7)
AUV Mapping of Axial Seamount, Juan de Fuca Ridge: The Southern Caldera Floor and Upper South Rift (2007) (7)
Increase in Mrp 1 expression and 4-hydroxy-2-nonenal adduction in heart tissue of Adriamycin-treated C 57 BL / 6 mice (2006) (7)
Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat (2016) (7)
Proteomic analysis of brain protein expression levels in NF-κβ p50 −/− homozygous knockout mice (2008) (7)
P4-162: Proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: Insights into the progression of this dementing disorder (2008) (7)
Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal‐derived extracellular vesicles (2021) (7)
Phosphoproteomics of Alzheimer disease brain: Insights into altered brain protein regulation of critical neuronal functions and their contributions to subsequent cognitive loss. (2019) (7)
Annexin A1 Complex Mediates Oxytocin Vesicle Transport (2013) (7)
Evidence of the immunomodulatory role of dual PI3K/mTOR inhibitors in transplantation: an experimental study in mice (2017) (7)
Redox Proteomics of Oxidatively Modified Brain Proteins in Mild Cognitive Impairment (2010) (7)
Healthy dietary intake moderates the effects of age on brain iron concentration and working memory performance (2021) (7)
Nanoceria distribution and effects are mouse-strain dependent (2020) (7)
Selective spin labeling of terminal galactose and N-acetylgalactosamine residues on the membrane surface of erythrocytes. (1984) (7)
Down syndrome: From development to adult life to Alzheimer disease. (2018) (7)
Time-Series Exploration and Biological, Geological, and Geochemical Characterization of the Rosebud and Calyfield Hydrothermal Vent Fields at 86°W and 89.5°W on the Galapagos Rift (2002) (7)
Protein and lipid oxidation following ischemia/reperfusion injury, the role of polyamines: an electron paramagnetic resonance analysis. (1996) (6)
Interaction of tacrine and velnacrine with neocortical synaptosomal membranes: Relevance to Alzheimer's disease (1993) (6)
In Vitro Cellular Assays for Oxidative Stress and Biomaterial Response (2016) (6)
Membrane fluidity and myotonia: Effects of cholesterol and desmosterol on erythrocyte membrane fluidity in rats with 20,25-diazacholesterol-induced myotonia and on phospholipid liposomes (1984) (6)
The effects of the extracellular manganese concentration and variation of the interpulse delay time in the CPMG sequence on water exchange time across erythrocyte membranes. (1990) (6)
Rapid variations in fluid chemistry constrain hydrothermal phase separation at the Main Endeavour Field (2017) (6)
Oxidative Stress and mTOR Activation in Down Syndrome Brain: Roles in Aβ42 and Tau Neuropathology and Transition to Alzheimer Disease-Like Dementia (2017) (6)
Spin-labeling studies of the conformation of the Ca(2+)-regulatory protein calmodulin in solution and bound to the membrane skeleton in erythrocyte ghosts: implications to transmembrane signaling. (1992) (6)
Fidelity of the PINK1 Knockout Rat to Oxidative Stress and Other Characteristics of Parkinson Disease. (2020) (6)
Stimulation of Epstein‐Barr virus‐infected human B cell growth by physiological concentrations of 4‐hydroxynonenal (2006) (5)
Electron paramagnetic resonance investigations of the effects of diethylstilbestrol on the physical state of membrane lipids and proteins (1980) (5)
Amyloid β-peptide(1–40)-mediated oxidative stress in cultured hippocampal neurons (2007) (5)
Oxidative Stress in Animal Models of Accelerated Aging, Alzheimer’s Disease and Huntington’s Disease (2004) (5)
Difluoromethylornithine decreases long-lasting protein oxidation induced by neonatal ethanol exposure in the hippocampus of adolescent rats. (2007) (5)
The 2013 Discovery Award from the Society for Free Radical Biology and Medicine : Selected Discoveries from the Butterfield Laboratory of Oxidative Stress and Its Sequelae in Brain in Cognitive Disorders Exemplified by Alzheimer Disease and Chemotherapy Induced Cognitive Impairment (2014) (5)
Immobilized Enzyme Reactions on Beads and Membranes (1996) (5)
Effects of domain-specific erythrocyte membrane modulators on acetylcholinesterase and NADH:cytochrome b5 reductase activities. (1990) (5)
Ubiquitin carboxyl-terminal hydrolase L-1 in brain: Focus on its oxidative/nitrosative modification and role in brains of subjects with Alzheimer disease and mild cognitive impairment. (2021) (5)
Chapter 11 – Biofunctional membranes: site-specifically immobilized enzyme arrays (2003) (5)
Time-dependence of, and effects of inhibition and cellular aging on, chloride efflux across erythrocyte membranes in Huntington's disease (1982) (5)
Proteomic identification of proteins oxidized by Abeta(1-42) in synaptosomes (2005) (4)
Spin labeling studies of membrane proteins in erythrocyte ghosts from patients with Huntington's disease (1983) (4)
Spotlight: Northwest Rota-1 Seamount (2010) (4)
Brain Protein Oxidation and Modification for Good or for Bad in Alzheimer’s Disease (2011) (4)
Metabolic Features of Brain Function with Relevance to Clinical Features of Alzheimer and Parkinson Diseases (2022) (4)
William R. Markesbery, M.D.: A legacy of excellence in Alzheimer's disease research and a life well-lived. (2010) (4)
Electron paramagnetic resonance studies of the effects of tri-n-butyltin on the physical state of proteins and lipids in erythrocyte membranes. (1991) (4)
Quinolinic acid, an endogenous metabolite with neurotoxic properties, alters the physical state of membrane proteins in human erythrocytes. (1984) (4)
Effects of beta-(N-methylamino)-L-alanine on cytoskeletal proteins of erythrocyte membranes. (1993) (4)
Erratum: Glutathionylation of the pro-apoptotic protein p53 in alzheimer's disease brain: Implications for AD pathogenesis (Neurochemical Research (2009) 34 (727-733) DOI 10.1007/s11064-009-9924-9 (2009) (4)
Specificity of biochemical and biophysical tests in Duchenne and myotonic muscular dystrophy, carrier states, and congenital myotonia. (1975) (4)
Zinc deficiency and the physical state of rat erythrocyte membrane proteins (1991) (4)
Benzodiazepine receptors in Huntington's disease (1988) (4)
Investigation of Peroxynitrite Induced Oxidative Stress in Red Blood Cells Monitored by Luminol-Dependent Chemiluminescence. (1999) (4)
CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down Syndrome. (2022) (4)
β-amyloid-Derived Free Radical Oxidation (1997) (4)
mTOR: Alzheimer's disease prevention for APOE4 carriers (2016) (4)
Group Report: How can we describe fluid-mineral processes and the related energy and material fluxes? (2003) (4)
BIOPHYSICAL STUDIES OF ERYTHROCYTE MEMBRANES IN HUNTINGTON'S DISEASE (1978) (4)
Lipids in Alzheimer’s Disease Brain (2009) (3)
Amyloid b-Peptide Effects on Synaptosomes from Apolipoprotein E-Deficient Mice * (2000) (3)
Amyloid β-Peptide(1-42), Oxidative Stress, and Alzheimer’s Disease (2007) (3)
Nitrated Proteins in the Progression of Alzheimer’s Disease: A Proteomics Comparison of Mild Cognitive Impairment and Alzheimer’s Disease Brain (2009) (3)
Onset of Senescence and Steatosis in Hepatocytes as a Consequence of a Shift in the Diacylglycerol/Ceramide Balance at the Plasma Membrane (2021) (3)
Sulfur Isotope Geochemistry of Mariana Arc Hydrothermal Systems (2004) (3)
EFFECTS OF OXIDATIVE STRESS ON THE MODEL THIOL PROTEASE-PAPAIN : AN INVESTIGATION OF CHANGES IN ACTIVITY AND STRUCTURE (1996) (3)
An Overview of Biofunctional Membranes for Tunable Separations, Metal-Ion Capture, and Enzyme Catalysis Based on Research from the Laboratories of Allan Butterfield and Dibakar Bhattacharyya (2008) (3)
Hydrothermal Systems on Kermadec Arc Volcanoes Revealed by PISCES V Submersible Dives (2005) (3)
Chemotherapy-induced cognitive impairment: focus on the intersection of oxidative stress and TNFα (2021) (3)
Mid-Ocean Ridges: Seafloor eruptions and evolution of hydrothermal fluid chemistry (1999) (3)
Overview of Vent Fluid Chemistry From the Marianas Volcanic Arc (2004) (3)
Chapter 4 – Nitric Oxide and Cellular Stress Response in Brain Aging and Neurodegenerative Disorders (2007) (3)
APOE in Alzheimer's disease and neurodegeneration (2020) (3)
Conformational altered p 53 as an early marker of oxidative stress in Alzheimer ' s disease (2017) (3)
A dihydromorphine-6-O-sulfate (1996) (3)
Liquid Carbon Dioxide Venting at the Champagne Hydrothermal Site, NW Eifuku Volcano, Mariana Arc (2004) (3)
Heme Oxygenase as a Therapeutic Funnel in Nutritional Redox Homeostasis and Cellular Stress Response (2009) (3)
Continuous, Long-term, Cyclic, Varied Eruptive Activity Observed at NW Rota-1 Submarine Volcano, Mariana Arc (2009) (3)
The Glutamatergic System in Alzheimer’s Disease Brain: Dysfunction Associated with Amyloid β-Peptide and Oxidative Stress (2004) (3)
The triangle of death of neurons, oxidative damage, mitochondrial dysfunction, and loss of choline-containing biomolecules, in brains of mice treated with doxorubicin: advanced insights into mechanisms of “chemobrain” (2018) (3)
Spontaneous Vertebrate Models of Alzheimer Dementia: Selectively Bred Strains (SAM Strains) (2011) (3)
Adenine and thymine grafts on polyethyleneimine (1989) (2)
Acetyl-l-Carnitine and Ferulic Acid Action in Aging and Neurodegenerative Diseases (2009) (2)
Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological diseases: Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and Duchenne muscular dystrophy. (1979) (2)
Reductive methylation of membrane proteins in human erythrocyte ghosts (1982) (2)
Extensive hydrothermal activity in the NE Lau basin revealed by ROV dives (2014) (2)
Disruption of endothelial barrier function: relationship to fluidity of membrane extracellular lamella. (1994) (2)
Spin labeling studies of wheat germ calmodulin in solution. (1991) (2)
Interactions of chlorpromazine with spin-labeled calmodulin : allosteric effects (1991) (2)
Intermediate products of sulfur disproportional reaction and their physical role in effusive to explosive submarine volcanic activity (2009) (2)
Mitochondrial Dysfunction in Nervous System Injury (2009) (2)
P4-237 Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain: insights into potential mechanisms of neurodegeneration (2004) (2)
Sulfur Lakes and Sulfur-rich Volcanic Hydrothermal Systems on the Mariana Arc (2007) (2)
Membrane Cytoskeletal Protein Alterations in Alzheimer's Disease (1995) (2)
Erratum: Nutritional approach to combat oxidative stress in Alzheimer's disease (review) (Journal of Nutritional Biochemistry (August 2002) 13:8 (444-461)) (2003) (2)
Brain Oxidative Stress in the Pathogenesis and Progression of Alzheimer’s Disease (2013) (2)
Morphological alterations in erythrocyte membranes induced by 9-amino-1,2,3,4-tetrahydroacridine and 9-aminoacridine. (1989) (2)
Neurobiology of Disease (2015) (2)
Protein Carbonylation in Brains of Subjects with Selected Neurodegenerative Disorders (2017) (2)
Tracking salt and magmatic gas in two hydrothermal observatories in the NE Pacific (2018) (2)
Erythrocyte membrane alterations in Huntington disease: effects of gamma-aminobutyric acid. (1978) (2)
Proteomics Identification of Oxidatively Modified Proteins in the Alzheimer’s Disease Brain and Models Thereof: Insights into Potential Mechanisms of Neurodegeneration (2005) (2)
Redox Proteomics and Metabolic Proteins in Brain of Subjects with Alzheimer's Disease, Mild Cognitive Impairment, and Models Thereof (2008) (2)
Tidal Variability in Diffuse Flow Vents in the Main Endeavour Field (2001) (2)
Deep submergence synergy (2003) (2)
Video Observations by Telepresence Reveal Two Types of Hydrothermal Venting on Kawio Barat Seamount (2010) (2)
RADICAL DECAY KINETICS IN FERROCYTOCHROME C MODEL MEMBRANES, A SPIN LABEL STUDY (1975) (2)
Research report Antisense directed at the Ah region of APP decreases brain oxidative markers in aged senescence accelerated mice (2004) (1)
Book reviewMembrane systems: Analysis and design. Applications in biotechnology, biomedicine, and polymer scienceWolf R. Vieth (Ed.), Hansen Publishers, Munich, 1988, XV + 360 pp, ISBN 3-446-15206-7. (1993) (1)
Hydrothermal systems and recent eruptive activity in the northern Lau Basin, South Pacific Ocean (2009) (1)
Effects of 9-amino-1,2,3,4-tetrahydroacridine (THA), a potential drug for treatment of Alzheimer's disease, on the physical state of human erythrocyte membranes. (1989) (1)
Potential Therapeutic Effects of Statins in Alzheimer’s Disease (2014) (1)
Gas Chemistry of Hydrothermal Systems of the Explorer Ridge, NE Pacific Ocean (2002) (1)
An Overview of the Lost City Vent Field: An Extensive Off-Axis, Serpentinite-Hosted Hydrothermal Field, 30° N, Mid-Atlantic Ridge (2001) (1)
Lack of p 53 Affects the Expression of Several Brain Mitochondrial Proteins : Insights from Proteomics into Important Pathways Regulated by p 53 (2017) (1)
apoE Isoform and Risk of Alzheimer Disease: Role of Abeta and the Lipid Peroxidation Product, HNE (2020) (1)
Disruption of the hippocampal and hypothalamic blood–brain barrier in a diet-induced obese model of type II diabetes: prevention and treatment by the mitochondrial carbonic anhydrase inhibitor, topiramate (2019) (1)
Redox Proteomics Identification of Oxidatively Modified Proteins in Alzheimer’s Disease Brain and in Brain from a Rodent Model of Familial Parkinson’s Disease: Insights into Potential Mechanisms of Neurodegeneration (2008) (1)
Tectonic and Volcanic Character of the Endeavour Ridge Axis From 1-m Resolution AUV Multibeam Mapping Surveys (2008) (1)
Differential Expression and Redox Proteomics Analyses of an Alzheimer Disease Transgenic Mouse Model: Effects of the Amyloid-β Peptide of APPΞ (2011) (1)
Water Movement Through Lipid Bilayers, Pores, and Plasma Membranes. Theory and Reality : Alan Finkelstein (Ed.), Wiley Interscience, New York, NY, 1987, 228 pages + xii. (1990) (1)
Biliverdin reductase-A: A novel drug target for atorvastatin in a dog preclinical model of Alzheimer’s disease (2012) (1)
Production of Isotopically Heavy Dissolved Organic Carbon in the Lost City Hydrothermal Vent Field (2005) (1)
Alzheimer’s Amyloid β-Peptide-Associated Oxidative Stress (2000) (1)
Oxidative Stress and the Triangle of Death in Alzheimer Disease Brain: The Aberrant Crosstalk among Energy Metabolism, MTOR Signaling and Protein Homeostasis Revealed by Redox Proteomics (2016) (1)
Redox signaling in neurodegeneration (2015) (1)
LOSS OF BILIVERDIN REDUCTASE-A FAVORS TAU HYPER-PHOSPHORYLATION IN ALZHEIMER DISEASE (2019) (1)
U and Th Concentration and Isotopic Composition of Hydrothermal Fluids at the Lost City Hydrothermal Field (2006) (1)
Functionality and architecture of the LOCUS distributed operating systems (1987) (1)
Selective spin labelling of sialic acid residues of glycoproteins and glycolipids in erythrocyte membranes (1)
Glutathionylation of the Pro-apoptotic Protein p53 in Alzheimer’s Disease Brain: Implications for AD Pathogenesis (2009) (1)
Up-Close Fluid Sampling at a Deep Submarine Lava Eruption (2006) (1)
Decreased expression and increased carbonylation of haptoglobin in plasma from MCI and AD subjects: Role of extracellular chaperones in Alzheimer’s disease (2012) (0)
P4-178: Oxidative damage in brain from human mutant APP/PS-1 double knock-in mice as a function of age (2008) (0)
Editorial Board (2012) (0)
Water transport across red-cell membranes following reductive methylation of the major transmembrane protein, Band 3: implications to increased divalent cation membrane permeability. (1990) (0)
Editorial Board (2013) (0)
Chemical properties and hydrothermal processes on the first two directly sampled deep-sea eruptions (Invited) (2009) (0)
Redox proteomic analysis of protein expression in aging brain: role of vitagenes and modulation by acetylcarnitine (2006) (0)
Field Calibration of the δ 11 B-pH Proxy in Corals and Calcified Algae at a Shallow Hydrothermal Vent and Adjacent Coral Reef (2015) (0)
Down Syndrome as a Special Case of Oxidatively Induced Developmental Dysregulation (2014) (0)
Erythrocyte membrane skeletal protein alterations induced by polyanions: implications to the osmotic-pulse incorporation of inositol hexaphosphate. (1989) (0)
Editorial Board (2013) (0)
The effect of hematocrit on water transport across human erythrocyte membranes: a 1H-T2 NMR study. (1989) (0)
Editorial Board (2011) (0)
Cell Cycle Proteins in Brain in Mild Cognitive Impairment: Insights into Progression to Alzheimer Disease (2011) (0)
Diet and Brain Aging (2013) (0)
Oxidative modification of brain proteins in Alzheimer's disease and models thereof: role of amyloid beta-peptide (1- 42) and insights from redox proteomics (2007) (0)
Dissolved Organic Carbon Distribution in Two Hydrothermal Systems - West Mata, NE Lau Basin during an eruption event and basement fluids from sediment-buried Juan de Fuca Ridge flanks (2009) (0)
OXIDATIVE STRESS IN BRAIN AND LYMPHOCYTE MITOCHONDRIA IN ALZHEIMER'S DISEASE AND AMNESTIC MILD COGNITIVE IMPAIRMENT: TOWARD IDENTIFICATION OF PERIPHERAL BIOMARKERS IN THE PROGRESSION OF THIS DEMENTING DISORDER (2014) (0)
56 - Disturbance of Protein Oxidation/degradation Homeostasis in Down Syndrome Brain Contributes to the Development of Alzheimer-Like Dementia (2015) (0)
Oceanographic Controls on Diffuse Flow Temperature Variability at Main Endeavour Field (2015) (0)
Lithium Isotopic Composition of Intra-Oceanic Arc Hydrothermal Fluids - Initial Results From the Tonga Kermadec Arc (2007) (0)
BILIVERDIN REDUCTASE-A MEDIATES THE BENEFICIAL EFFECTS OF INTRANASAL INSULIN ADMINISTRATION ON AD PATHOLOGY IN THE BRAIN OF 3XTG-AD MICE (2017) (0)
Proteomic Analysis of Brain from an Alzheimer Disease Transgenic Mouse Model with a Third Mutation in Amyloid Precusor Protein (M631L): in Vivo Effects of the Single Methionine Residue of Aβ(142) and Relevance to Alzheimer Disease (2011) (0)
[0091]Analysis of HO-1/BVR post translational modifications as potential plasma biomarker of Alzheimer’s disease (AD) pathology (2012) (0)
Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat (2016) (0)
Explosive Deep Sea Volcanism Produces Composite Volcanoes (Stratocones) with Predominantly Diffuse Flow Hydrothermal Ecosystems (2018) (0)
Oxidative Stress Following High Dose Chemotherapy with Autologous Stem Cell Transplant (2016) (0)
Symp. 4.1Prognostic biomarkers of oxidative stress in Alzheimer’s disease (2012) (0)
Cellular stress response in aging brain: A redox proteomics approach (2006) (0)
Editorial Board (2015) (0)
P4-177: Assessing immune-related oxidative stress and proteomics in a mouse model of Alzheimer's disease (2008) (0)
Loss Of Biliverdin Reductase-A (BVR-A) Impairs Brain Energy Metabolism Favoring The Development Of Neurodegeneration: A Link Between AD And T2DM (2022) (0)
Hydrothermal exploration of the Mariana Back Arc Basin: Chemical Characterization (2016) (0)
ESR studies of transmembrane signaling processes: modulation of skeletal protein-protein interactions and their influence on the physical state of cell-surface carbohydrates in human erythrocyte membranes. (1989) (0)
43 – Biliverdin Reductase-A Inactivation Promotes Insulin Resistance in Alzheimer Disease: A New Paradigm (2015) (0)
The Nature of Sulfide Weathering in the Submarine Environment: Evidence From the Southern Explorer Ridge. (2002) (0)
P4-176: Proteomics determined glycoproteome in mild cognitive impairment, early Alzheimer's disease, and late-stage Alzheimer's disease hippocampus and inferior parietal lobule (2008) (0)
Detection of Carbonylated Proteins in 2-D SDS Page Separations (2008) (0)
SFRBM 2013 DISCOVERY AWARD LECTUREP1 - PATHOGENESIS AND PROGRESSION OF ALZHEIMER DISEASE AND POTENTIAL MECHANISMS OF CHEMOTHERAPY INDUCED COGNITIVE IMPAIRMENT: ROLES OF OXIDATIVE STRESS AND INSIGHTS FROM REDOX PROTEOMICS (2013) (0)
EPR investigations of free radical induced alterations in neocortical synaptosomal membrane protein infrastructure: Relevance to ageing and Alzheimer's disease (1993) (0)
Electron Paramagnetic Resonance Spin-Labeling Analysis of Synaptosomal Membrane Protein Oxidation (2003) (0)
Oxidative stress in Alzheimer disease and mild cognitive impairment: evidence from human data provided by redox proteomics (2015) (0)
OXIDATIVE STRESS AND THE PROGRESSION OF ALZHEIMER DISEASE: THE TRIANGLE OF DEATH FOR NEURONS ASSOCIATED WITH ALTERED GLUCOSE METABOLISM, mTOR SIGNALING, AND PROTEIN PHOSPHORYLATION (2015) (0)
Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease (2019) (0)
20 - Proteomics Insights into Molecular Mechanisms Engaged Prior to and Following Development of Alzheimer’s Disease (AD) Neuropathology in Down Syndrome (DS) Brain: Relevance to Oxidative Stress and Neuropathology of Both DS and AD (2014) (0)
HNE-mediated proinflammatory microenvironment in Acute Lymphoblastic Leukemia: Insights into the roles of extracellular vesicles and oxidative stress (2022) (0)
Editorial Board (2014) (0)
Characterization of Recently Located Methane Seeps on the Cascadia Margin (2018) (0)
Abstract 4343: Inhibition of fatty acid synthase reduces mitochondrial respiration and addiction of colorectal cancer cells to glycolysis (2014) (0)
New Insights into Oceanic Spreading Centers from Seafloor Observatories Posters (2018) (0)
Seawater carbonate chemistry and Bathymodiolus brevior shell variables near Eifuku volcano, Japan, 2009 (2009) (0)
Serum extracellular vesicles identified distinct 4-HNE targeted signatures in Alzheimer’s patients with prior cancer history (2020) (0)
Oxidative stress and mTOR in Down syndrome brain: Link to Alzheimer's dysmetabolism, neuropathology, and possible therapies (2022) (0)
Editorial Board (2012) (0)
Synergistic effect of sorafenib and fh535 combination on hepatocellular carcinoma by targeting cell bioenergetics and mitochondrial integrity (2017) (0)
5 Amyloid β-Peptide ( 1-42 ) , Oxidative Stress , and Alzheimer ’ s Disease (2006) (0)
Loss of biliverdin reductase‐a (BVR‐A) impairs beneficial effects of CNS insulin on brain energy metabolism favoring the development of Alzheimer's disease (AD) neuropathology (2020) (0)
Abstract 1119: S100A4 alters mitochondrial metabolism to promote invasion and metastasis of non-small cell lung cancer cells through upregulation of NDUFS2 (2019) (0)
Different oxidative profiles induced by over-expression of mutant and wild-type APP in HEK cells. (2009) (0)
Biliverdin reductase-A: A novel drug target for atorvastatin and relevance to statin-mediated reduced risk of developing Alzheimer’s disease (2013) (0)
Protective effect of ferulic acid ethyl ester against amyloid beta peptide (1-42)-induced oxidative stress in synaptosomes: implications for Alzheimer disease (2005) (0)
CELLULAR STRESS RESPONSE IN AGING BRAIN AND NEURODEGENERATIVE DISORDERS: EFFECT OF ACETYLCARNITINE (2006) (0)
Extracellular Vesicles, Potential Non-invasive Markers of Cancer Therapy, Induce Neurotoxicity (2020) (0)
Sub-seafloor Processes and the Composition of Diffuse Hydrothermal Fluids (2002) (0)
Editorial Board (2014) (0)
Membrane structure and function, volume 3. Edited by E. Edward Bittar, 183 pp, John Wiley & Sons, New York, NY, 1980. $22.50 (1981) (0)
Active volcanic and hydrothermal processes at NW Rota-1 submarine volcano; Mariana volcanic arc (2004) (0)
Hydrothermal activity and rift-induced tracers at Axial (Juan de Fuca Ridge): results of cruise SO-109 of RV SONNE-ROPOS (1997) (0)
Data collected from Miniature Autonomous Plume Recorders (MAPRs) deployed near the Axial Seamount on the Juan de Fuca Ridge on R/V Thomas G. Thompson TN327 in August 2015 and collected in July 2017. (2019) (0)
Reflections on Mentoring Undergraduate Research (2003) (0)
Editorial Board (2011) (0)
Non-Covalent Immobilization of Papain Onto Modified Polysulfone Membrane Using Avidin-Biotin Coupling: EPR and Kinetic Studies (1996) (0)
ABERRANT POLYUBIQUITOME PROFILE IN DOWN SYNDROME AND ALZHEIMER DISEASE BRAIN (2017) (0)
Geologic, chemical, and biologic evidence for Recent volcanism at 17.5 degrees S (1997) (0)
P4-175: Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer's disease (2008) (0)
Improvement of BVR-A Activity Ameliorates Brain Insulin Resistance in Alzheimer Disease Following Intranasal Insulin Administration (2016) (0)
CELLULAR STRESS RESPONSE (HORMESIS) IN RESPONSE TO BIOACTIVE NUTRACEUTICALS WITH RELEVANCE TO ALZHEIMER DISEASE. (2023) (0)
Redox proteomics in some age-related neurodegenerative disorders or models thereof (2006) (0)
2Chapter 3 Acetyl-l-Carnitine and Ferulic Acid Action in Aging and Neurodegenerative Diseases (2009) (0)
Oxidative Stress Links Brain Insulin Resistance and Mitochondrial Defects in Down Syndrome Brain Early in Life: Implication for Neurodegeneration (2020) (0)
Spin labeling studies of the interactions of potentially useful therapeutic agents for the treatment of Alzheimer’s disease with cytoskeletal proteins in erythrocyte ghosts and brain synaptosomal membranes (1992) (0)
Gas Chemistry of Submarine Hydrothermal Venting at Maug Caldera, Mariana Arc (2014) (0)
Enhancement of the Yu and Ledeen gas-liquid Supplementary key words N-acetylneuraminic acid . erythro- (1980) (0)
Selective reduction of oxidative stress markers in the SAMP8 mouse brain by a distinct spearmint extract with antioxidant properties. (P4.078) (2015) (0)
Ubiquitome Profile in Down Syndrome Brain: Understanding the Mechanisms of Neurodegeneration (2016) (0)
Dietary Modulation of Nitrosative Damage in Brain Aging by Vitamin D (2012) (0)
Gas Chemistry of Hydrothermal Systems of the Northern Lau Basin - New Results (2013) (0)
Quantitative proteomics analysis of phosphorylated proteins in the hippocampus of Alzheimer disease subjects (2011) (0)
Electron Spin Resonance Studies of Fatty Acidd & wxl Alterations in Membrane Fluidity in Cultured Eduthelial Cells (2003) (0)
Biological magnetic resonance: Vol. 3, edited by L. J. Berliner and J. Reuben. Plenum Press, New York, 1981. 268 pages. $35.00 ($42.00 outside U.S.A.) (1982) (0)
A (25-35) PEPTIDE DISPLAYS H 0 -LIKE REACTIVITY TOWARDS AQUEOUS FE 8+ , NITROXIDE SPIN PROBES, ibib SYNAPTOSOMAL MEMBRANE PROTEINS (2003) (0)
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome (2018) (0)
Nanoceria distribution, biotransformation, and safety/toxicity in the rat (2012) (0)
Exercise-mediated alteration of protein redox states in plasma: a possible stimulant for hormetic response (2007) (0)
Editorial Board (2017) (0)
Methods of Evaluating Protein Oxidation Induced by Ischemia/Reperfusion Injury (1997) (0)
Preface for the Special Issue of Neuromolecular Medicine in Memory of the Life and Legacy of William R. Markesbery, M.D. (2011) (0)
Blockade of glutamine synthetase enhances inflammatory response (2018) (0)
22 Lipids in Alzheimer ’ s Disease Brain (2009) (0)
Chapter 7 Insights from Proteomics into Mild Cognitive Impairment , Likely the Earliest Stage of Alzheimer ' s Disease (2013) (0)
Lipopolysaccharide impairs amyloid beta efflux from brain: altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood–brain barrier (2012) (0)
Aggregation and loss of activity of lyophilized RNase: Evidence of iron-catalyzed free radical formation and reaction with oxygen (1990) (0)
Review - Part of the Special Issue: Alzheimer's Disease - Amyloid, Tau and Beyond Statins more than cholesterol lowering agents in Alzheimer disease: Their pleiotropic functions as potential therapeutic targets (2014) (0)
Electron Spin Resonance Studies of Erythrocytes from Patients with Myotonic Muscular Dystrophy ( membrane / spin label / autosomal dominant trait (0)
4-Hydroxynonenal mediates cyclosporine promoted EBV-induced B cell transformation (2004) (0)
Oxidative Stress in Brain in Amnestic Mild Cognitive Impairment (2023) (0)
Molecular Diversity and Activity of Methanogens in the Subseafloor at Deep-Sea Hydrothermal Vents of the Pacific Ocean (Invited) (2009) (0)
Mitochondrial Dysfunction in Nervous System Injury 887 Author ' s personal copy Mitochondrial Dysfunction in Nervous System Injury (2008) (0)
Biosignal transduction mechanisms : Michiki Kasai, Tohru Yoshioka, and Hideo Suzuki (Eds.), Japan Scientific Societies Press (Tokyo) and Springer-Verlag (Berlin), 1989, 209 + xii pp., $61.60. (1990) (0)
Editorial Board (2014) (0)
44 - Insulin Resistance and Autophagy Dysfunction in Brain in the Progression of Alzheimer Disease: Role of Elevated Oxidative Stress and Link of T2DM to Increased Risk of AD (2015) (0)
Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease (2018) (0)
Editorial Board (2016) (0)
Rapid communication Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid -peptide (1-42) in a transgenic Caenorhabditis elegansmodel (2003) (0)
The preparation temperature influences the physicochemical nature and activity of nanoceria (2021) (0)
Assessment of chemotherapy-induced cognitive impairment: A prospective study of the biochemical and metabolic effects of platinum/taxane-based chemotherapy in gynecologic cancer patients. (2021) (0)
Chapter 32 SAMP 8 : A model to understand the role of oxidative stress in age-related diseases including Alzheimer ’ s disease (2012) (0)
HNE.O.5Doxorubicin-induced HNE adduction to ApoA1 in plasma leads to elevated brain-resident TNF-alpha with consequent oxidative stress, mitochondrial dysfunction, and neuronal death: Prevention by MESNA and implications for chemotherapeutic induced cognitive dysfunction (“chemobrain”) (2012) (0)
The effect of low sulfate in the Precambrian oceans on seawater-basalt reaction traced by triple oxygen and strontium isotopes (2019) (0)
The Interplay Among Oxidative Stress, Brain Insulin Resistance and AMPK Dysfunction Contribute to Neurodegeneration in Type 2 Diabetes and Alzheimer Disease (2022) (0)

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